Hsd11b1

Reference Set (100 Compounds)

Cn1c(-c2ccccc2C(F)(F)F)nnc1C12CCC(c3nc(-c4ccc(F)cc4)no3)(CC1)CC2 ZINC000003960657

ZINC000003960657 (search)

O=C(CN1CC[C@H](C(F)(F)F)C1)NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2 ZINC000101111697

ZINC000101111697 (search)

CCS(=O)(=O)CCC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2 ZINC000043128373

ZINC000043128373 (search)

Cn1c2c(c(=O)n1-c1cccc(I)c1)[C@H]1CC[C@]2(C)C1(C)C ZINC000141795126

ZINC000141795126 (search)

C[C@H](C(=O)NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 ZINC000100066011

ZINC000100066011 (search)

Nc1c(Cl)cc(C(=O)N2C3CC4CC(C3)CC2C4)cc1Cl ZINC000036286461

ZINC000036286461 (search)

CCOC(=O)[C@H]1CC[C@@H](N(C(=O)c2cc(Cl)c(N)c(Cl)c2)C2CC2)CC1 ZINC000253951945

ZINC000253951945 (search)

Cn1c(-c2ccccc2C(F)(F)F)nnc1C12CCC(c3noc(C(C)(F)F)n3)(CC1)CC2 ZINC000060325424

ZINC000060325424 (search)

Cn1c2c(c(=O)n1-c1cc(Cl)ccc1Cl)[C@H]1CC[C@]2(C)C1(C)C ZINC000035278159

ZINC000035278159 (search)

C[C@H]1CN(c2ncccc2N)C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1 ZINC000096316656

ZINC000096316656 (search)

Nc1c(Cl)cc(C(=O)N(C2CC2)[C@H]2CC[C@@H](C(=O)N3CCCC3)CC2)cc1Cl ZINC000261071574

ZINC000261071574 (search)

Nc1c(Cl)cc(C(=O)N(C2CCCCC2)C2CC2)cc1Cl ZINC000036286482

ZINC000036286482 (search)

O=C(CN1CCN(c2ccc(C(F)(F)F)cn2)CC1)NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2 ZINC000100065976

ZINC000100065976 (search)

C[C@H]1CN(c2ccccn2)C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1 ZINC000036286426

ZINC000036286426 (search)

CN(C(=O)c1cc(Cl)c(N)c(Cl)c1)C12CC3CC(CC(C3)C1)C2 ZINC000036286455

ZINC000036286455 (search)

CC(C)(C)N1CCN(c2ccc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(C(N)=O)(C6)C5)c4ccccc43)nc2)CC1 ZINC000101676334

ZINC000101676334 (search)

CC1(C)C[C@H]2C[C@@](C)(CN2C(=O)c2cc(Cl)c(N)c(Cl)c2)C1 ZINC000101099852

ZINC000101099852 (search)

NC(=O)C12CC3C[C@@H](C1)C(NC(=O)N1CCN(c4ccc(N5CCN(S(=O)(=O)C6CC6)CC5)cn4)c4ccccc41)[C@@H](C3)C2 ZINC000101676354

ZINC000101676354 (search)

CN1CCN(C(=O)[C@H]2CC[C@@H](N(C(=O)c3cc(Cl)c(N)c(Cl)c3)C3CC3)CC2)CC1 ZINC000253731982

ZINC000253731982 (search)

CCS(=O)(=O)CC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2 ZINC000071316756

ZINC000071316756 (search)

Cn1c2c(c(=O)n1Cc1ccccc1C(F)(F)F)[C@H]1CC[C@]2(C)C1(C)C ZINC000035285346

ZINC000035285346 (search)

Cn1c2c(c(=O)n1-c1ccccc1C(F)(F)F)[C@H]1CC[C@]2(C)C1(C)C ZINC000142431365

ZINC000142431365 (search)

CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccccc2F)n1Cc1ccccc1 ZINC000035285341

ZINC000035285341 (search)

CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccc(F)cc2F)n1Cc1ccccc1 ZINC000035285343

ZINC000035285343 (search)

C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(N2CC[C@@H](O)C2)c1 ZINC000040935615

ZINC000040935615 (search)

C[C@H](C(=O)NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2)N1CCc2ccc3c(c2CC1)OCO3 ZINC000101111654

ZINC000101111654 (search)

CCOC(=O)CN1C[C@H](C)N(C(=O)c2cc(Cl)c(N)c(Cl)c2)[C@H](C)C1 ZINC000036286431

ZINC000036286431 (search)

COC(=O)CN(C)C(=O)[C@H]1CC[C@@H](N(C(=O)c2cc(Cl)c(N)c(Cl)c2)C2CC2)CC1 ZINC000261088291

ZINC000261088291 (search)

CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccccc2)n1Cc1ccccc1 ZINC000035285332

ZINC000035285332 (search)

CS(=O)(=O)N1CCN(c2ccc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(O)(C6)C5)c4ccccc43)nc2)CC1 ZINC000101676247

ZINC000101676247 (search)

Nc1c(Cl)cc(C(=O)N(C2CCCC2)C2CC2)cc1Cl ZINC000036286437

ZINC000036286437 (search)

CN(C)CCNC(=O)[C@H]1CC[C@@H](N(C(=O)c2cc(Cl)c(N)c(Cl)c2)C2CC2)CC1 ZINC000253862585

ZINC000253862585 (search)

CCn1c2c(c(=O)n1-c1ccccc1)[C@H]1CC[C@]2(C)C1(C)C ZINC000139780323

ZINC000139780323 (search)

CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccc(F)cc2F)n1CCc1ccccc1 ZINC000142298862

ZINC000142298862 (search)

CC(C)(C)N1CCN(c2ccc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(O)(C6)C5)c4ccccc43)nc2)CC1 ZINC000101676292

ZINC000101676292 (search)

COc1ccccc1N1C[C@H](C)N(C(=O)c2cc(Cl)c(N)c(Cl)c2)[C@H](C)C1 ZINC000036286440

ZINC000036286440 (search)

Nc1c(Cl)cc(C(=O)N(C2CC2)[C@H]2CC[C@@H](C(=O)NCC(=O)O)CC2)cc1Cl ZINC000261153316

ZINC000261153316 (search)

Cc1ccccc1-c1cccc(Cn2c(=O)c3c(n2C)[C@]2(C)CC[C@H]3C2(C)C)c1 ZINC000169353226

ZINC000169353226 (search)

O=C(NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2)N1CCN(c2ccc(N3CCN(S(=O)(=O)C4CC4)CC3)cn2)c2ccccc21 ZINC000101676315

ZINC000101676315 (search)

CC(C)n1c2c(c(=O)n1-c1ccccc1F)[C@H]1CC[C@]2(C)C1(C)C ZINC000035285337

ZINC000035285337 (search)

CCOC(=O)c1cccnc1N1C[C@H](C)N(C(=O)c2cc(Cl)c(N)c(Cl)c2)[C@H](C)C1 ZINC000036286445

ZINC000036286445 (search)

CS(=O)(=O)N1CCN(c2ccc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(C(N)=O)(C6)C5)c4ccccc43)cc2)CC1 ZINC000101676278

ZINC000101676278 (search)

CS(=O)(=O)N1CCN(c2cnc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(O)(C6)C5)c4ccccc43)nc2)CC1 ZINC000101676236

ZINC000101676236 (search)

C[C@](O)(c1ccc(C(=O)N(C2CC2)[C@H]2CC[C@](COC(N)=O)(c3cscn3)CC2)cc1)C(F)(F)F ZINC000101390124

ZINC000101390124 (search)

CC(C)(CC(=O)NC1CC1)CC(=O)NC1[C@H]2CC3C[C@H]1CC(C(N)=O)(C3)C2 ZINC000101272423

ZINC000101272423 (search)

C=CCn1c2c(c(=O)n1-c1ccccc1F)[C@H]1CC[C@]2(C)C1(C)C ZINC000141976351

ZINC000141976351 (search)

Cn1c2c(c(=O)n1-c1ccccc1Cl)[C@H]1CC[C@]2(C)C1(C)C ZINC000035285335

ZINC000035285335 (search)

C[C@@H]1CC(n2c(=O)[nH]c3ccccc32)C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1 ZINC000096272861

ZINC000096272861 (search)

C[C@@H]1CC(N2CCNC2=O)C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1 ZINC000036286466

ZINC000036286466 (search)

Nc1c(Cl)cc(C(=O)N(C2CC2)[C@H]2CC[C@@H](C(=O)NCc3ccccc3)CC2)cc1Cl ZINC000261118992

ZINC000261118992 (search)

COc1cccc(-n2c(=O)c3c(n2C)[C@]2(C)CC[C@H]3C2(C)C)c1 ZINC000141778448

ZINC000141778448 (search)

C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(N2CCN(C)CC2)c1 ZINC000040935797

ZINC000040935797 (search)

C[C@H](C(=O)NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2)N1CC(Oc2ccccc2F)C1 ZINC000101064679

ZINC000101064679 (search)

N#CC1(COc2nc(C3CC3)c(C(=O)NC3[C@H]4CC5C[C@H]3CC(O)(C5)C4)s2)CC1 ZINC000103246963

ZINC000103246963 (search)

CC(=O)N1CCN(c2ccc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(O)(C6)C5)c4ccccc43)nc2)CC1 ZINC000101676300

ZINC000101676300 (search)

Nc1c(Cl)cc(C(=O)N(C2CC2)[C@H]2CC[C@@H](C(=O)NCC3CCCCC3)CC2)cc1Cl ZINC000253684698

ZINC000253684698 (search)

COc1ccc(-c2cnc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(C(N)=O)(C6)C5)c4ccccc43)nc2)cc1 ZINC000101676216

ZINC000101676216 (search)

Cn1c2c(c(=O)n1Cc1ccccc1)[C@H]1CC[C@]2(C)C1(C)C ZINC000140234245

ZINC000140234245 (search)

C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(-n2cncn2)c1 ZINC000039290216

ZINC000039290216 (search)

CSc1nc(N2C[C@H]3[C@@H](C2)[C@@H]3C(=O)O)ccc1C(=O)NC12CC3CC(CC(C3)C1)C2 ZINC000169322464

ZINC000169322464 (search)

CC(C)(C)c1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccc(C(=O)O)cc1 ZINC000095578030

ZINC000095578030 (search)

C[C@](O)(c1ccc(C(=O)N(C2CC2)[C@H]2CC[C@](COC(N)=O)(c3ccccc3)CC2)cc1)C(F)(F)F ZINC000101390093

ZINC000101390093 (search)

CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@@](C)(C(=O)O)CC[C@]3(C)CC[C@]21C ZINC000019203131

ZINC000019203131 (search)

Cc1ccc(-n2c(=O)c3c(n2C)[C@]2(C)CC[C@H]3C2(C)C)cc1 ZINC000141743132

ZINC000141743132 (search)

COc1ccc(-c2cnc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(OC(N)=O)(C6)C5)c4ccccc43)nc2)cc1 ZINC000101676228

ZINC000101676228 (search)

CCCn1c2c(c(=O)n1-c1ccccc1F)[C@H]1CC[C@]2(C)C1(C)C ZINC000141486267

ZINC000141486267 (search)

COc1ccc(-c2cnc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(O)(C6)C5)c4ccccc43)nc2)cc1 ZINC000101676198

ZINC000101676198 (search)

C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(OC(C)(C)C(=O)O)c1 ZINC000043199704

ZINC000043199704 (search)

CS(=O)(=O)N1CCN(c2ccc(N3CCN(C(=O)NC4[C@H]5CC6C[C@H]4CC(O)(C6)C5)c4ccccc43)cc2)CC1 ZINC000101676264

ZINC000101676264 (search)

Cn1c2c(c(=O)n1-c1ccccc1)[C@@H]1CC[C@@]2(C)C1(C)C ZINC000142375537

ZINC000142375537 (search)

O=C(/C=C/c1ccccc1Br)/C=C/c1ccccc1Br ZINC000040979901

ZINC000040979901 (search)

Cn1c2c(c(=O)n1-c1ccccc1)[C@H]1CC[C@]2(C)C1(C)C ZINC000141078785

ZINC000141078785 (search)

C[C@@H]1C[C@H](n2c(=O)oc3ccccc32)CCN1C(=O)c1cc(Cl)c(N)c(Cl)c1 ZINC000036286458

ZINC000036286458 (search)

C[C@](O)(c1ccc(C(=O)N(C2CC2)[C@H]2CC[C@](COC(N)=O)(c3ccccc3F)CC2)cc1)C(F)(F)F ZINC000101390112

ZINC000101390112 (search)

O=C1/C(=C/c2ccccc2Br)CCC/C1=C\c1ccccc1Br ZINC000020115445

ZINC000020115445 (search)

C[C@@H]1CC(n2c(=O)oc3ccccc32)C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1 ZINC000036286463

ZINC000036286463 (search)

O=C1N=C(NC23C[C@@H]4CC2C[C@H](C4)C3)SC12CCCC2 ZINC000100404270

ZINC000100404270 (search)

Nc1c(Cl)cc(C(=O)N2CCCN(Cc3ccccc3)CCC2)cc1Cl ZINC000036286476

ZINC000036286476 (search)

C[C@](O)(c1ccc(C(=O)N(C2CC2)[C@H]2CC[C@](COC(N)=O)(c3ccccn3)CC2)cc1)C(F)(F)F ZINC000101390119

ZINC000101390119 (search)

O=C(/C=C/c1ccc(F)cc1)/C=C/c1ccc(F)cc1 ZINC000001081487

ZINC000001081487 (search)

C[C@](O)(c1ccc(C(=O)N(C2CC2)[C@H]2CC[C@](O)(C3CC3)CC2)cc1)C(F)(F)F ZINC000101176322

ZINC000101176322 (search)

O=S1(=O)N=C(NC2CCCCC2)O[C@H]2CCCC[C@H]21 ZINC000096273925

ZINC000096273925 (search)

CS(=O)(=O)NCCC(=O)N1CCC(c2cc(C(=O)N3CCC[C@H]4CCCC[C@H]43)cs2)CC1 ZINC000165357211

ZINC000165357211 (search)

COc1cc(/C=C/C(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O ZINC000006483730

ZINC000006483730 (search)

C[C@H](NC1=NC(=O)[C@](C)(C(C)(C)O)S1)c1ccc(F)cc1 ZINC000039205342

ZINC000039205342 (search)

O=C1/C(=C/c2cccc(Br)c2)CC/C1=C\c1cccc(Br)c1 ZINC000004547071

ZINC000004547071 (search)

COc1ccc(-c2cnc(N3CCN(C(=O)N4CC[C@H](c5cn[nH]c5)C4)c4ccccc43)nc2)cc1 ZINC000071318227

ZINC000071318227 (search)

O=C1/C(=C/c2ccc(O)cc2)CCC/C1=C\c1ccc(O)cc1 ZINC000004603546

ZINC000004603546 (search)

CC(C)(CC(=O)NC1CC1)CC(=O)NC1[C@H]2CC3C[C@H]1CC(O)(C3)C2 ZINC000101272381

ZINC000101272381 (search)

O=C(/C=C/c1ccc(O)cc1)/C=C/c1ccc(O)cc1 ZINC000006092599

ZINC000006092599 (search)

O=C1/C(=C/c2ccc(F)cc2)CCC/C1=C\c1ccc(F)cc1 ZINC000004482197

ZINC000004482197 (search)

O=S1(=O)N=C(NC2CCCCC2)O[C@@H]2CCCC[C@H]21 ZINC000096273924

ZINC000096273924 (search)

O=C1/C(=C/c2ccccc2Br)CC/C1=C\c1ccccc1Br ZINC000020115441

ZINC000020115441 (search)

Nc1c(Cl)cc(C(=O)N2C[C@H]3C[C@H]2CN(Cc2ccccc2)C3)cc1Cl ZINC000101071991

ZINC000101071991 (search)

O=C1/C(=C/c2ccc(F)cc2)CC/C1=C\c1ccc(F)cc1 ZINC000004482199

ZINC000004482199 (search)

COc1cc(/C=C/C(=O)/C=C(O)/C=C/c2ccc(O)c(OC)c2)ccc1O ZINC000100067274

ZINC000100067274 (search)

CCCSc1nc(N2CCC[C@@H](CC(=O)O)C2)ccc1C(=O)NC1CCCCC1 ZINC000095575356

ZINC000095575356 (search)

CN(C)CCCOc1ccc(/C=C2\CC/C(=C\c3ccc(OCCCN(C)C)cc3)C2=O)cc1 ZINC000029128204

ZINC000029128204 (search)

COc1ccc(N2C(=O)C(C)(C)[C@@H]2c2ccccc2OC)cc1 ZINC000169324238

ZINC000169324238 (search)

CCOc1ccc(/C=C/C(=O)/C=C/c2ccc(OCC)cc2)cc1 ZINC000000028155

ZINC000000028155 (search)