Drd4

Reference Set (131 Compounds)

CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3 ZINC000000009073

ZINC000000009073 (search)

NCCc1ccc(O)c(O)c1 ZINC000000033882

ZINC000000033882 (search)

CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 ZINC000019796155

ZINC000019796155 (search)

c1ccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)nc1 ZINC000025427051

ZINC000025427051 (search)

Fc1ccc2[nH]c(CN3CCN(c4ccccn4)CC3)cc2c1 ZINC000013560675

ZINC000013560675 (search)

CN(CC[C@@H](Oc1ccc(C(F)(F)F)cc1)c1ccccc1)CC(=O)O ZINC000013816272

ZINC000013816272 (search)

COc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1 ZINC000028770345

ZINC000028770345 (search)

Fc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000053045062

ZINC000053045062 (search)

C=Cc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000028769047

ZINC000028769047 (search)

Fc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1 ZINC000028769079

ZINC000028769079 (search)

COc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000028771301

ZINC000028771301 (search)

Clc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000095803215

ZINC000095803215 (search)

CSc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000096901419

ZINC000096901419 (search)

CCc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000028770344

ZINC000028770344 (search)

CCCc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000028769981

ZINC000028769981 (search)

FC(F)(F)c1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 ZINC000053084151

ZINC000053084151 (search)

c1ccc(-c2ccc(N3CCN(Cc4c[nH]c5ncccc45)CC3)cc2)cc1 ZINC000028769976

ZINC000028769976 (search)

O=C(NCCN1CCN(c2noc3ccccc23)CC1)c1ccc(F)cc1 ZINC000064527531

ZINC000064527531 (search)

c1cnc(N2CCN(CCCCc3nc4ccccc4s3)CC2)nc1 ZINC000084670852

ZINC000084670852 (search)

N#Cc1cccnc1N1CCN(CCNC(=O)c2ccc(F)cc2)CC1 ZINC000064527248

ZINC000064527248 (search)

Cc1ccc(N2CCN(CCCOc3ccc(F)cc3)CC2)nc1 ZINC000169350277

ZINC000169350277 (search)

OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccc(F)cc2)CC1 ZINC000073224424

ZINC000073224424 (search)

COc1cccc(C(=O)NCCN2CCN(c3ncccc3C#N)CC2)c1 ZINC000064527542

ZINC000064527542 (search)

O=C(NCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 ZINC000056965892

ZINC000056965892 (search)

Fc1ccc(OCCCN2CCN(c3ccccn3)CC2)cc1 ZINC000001888141

ZINC000001888141 (search)

COc1cccc(C(=O)NCCN2CCN(c3noc4ccccc34)CC2)c1 ZINC000064539120

ZINC000064539120 (search)

OC1(c2ccc(Cl)cc2)CCN(CCCSc2ccc(F)cc2)CC1 ZINC000073219170

ZINC000073219170 (search)

OC1(c2ccc(Cl)cc2)CCN(CCCOc2ccc(F)cc2)CC1 ZINC000073224909

ZINC000073224909 (search)

Clc1ccc(N2CCN(Cc3cnn4ccccc34)CC2)cc1 ZINC000013438692

ZINC000013438692 (search)

Cc1ccc(N2CCN(CCNC(=O)c3ccc(F)cc3)CC2)cc1 ZINC000064527704

ZINC000064527704 (search)

O=C(NCCN1CCN(c2ccc(Cl)cn2)CC1)c1ccc(F)cc1 ZINC000064527520

ZINC000064527520 (search)

Fc1ccc(CCCCN2CCN(c3ccccn3)CC2)cc1 ZINC000001888172

ZINC000001888172 (search)

c1cnc(N2CCN(CCCc3nc4ccccc4s3)CC2)nc1 ZINC000169350288

ZINC000169350288 (search)

Clc1ccc(N2CCN(CCCCc3nc4ccccc4s3)CC2)cc1 ZINC000084724332

ZINC000084724332 (search)

Fc1ccc(OCCCN2CCN(c3ncccn3)CC2)cc1 ZINC000060992903

ZINC000060992903 (search)

c1ccc(OCCCN2CCN(c3ccccc3)CC2)cc1 ZINC000033854708

ZINC000033854708 (search)

COc1cccc(C(=O)NCCN2CCN(c3ccc(Cl)cc3)CC2)c1 ZINC000053156515

ZINC000053156515 (search)

Clc1ccc(N2CCN(CCCOc3ccccc3)CC2)cc1 ZINC000073220413

ZINC000073220413 (search)

Fc1ccc(SCCCN2CCN(c3ccccn3)CC2)cc1 ZINC000073222863

ZINC000073222863 (search)

O=C1c2ccc(F)cc2C[C@@H]1CCN1CCN(c2ccc(Cl)cc2)CC1 ZINC000169350269

ZINC000169350269 (search)

Fc1ccc(CCCCN2CCN(c3ncccn3)CC2)cc1 ZINC000082158461

ZINC000082158461 (search)

O=C(CCCN1CCN(c2ncccn2)CC1)c1ccc(F)cc1 ZINC000013730842

ZINC000013730842 (search)

Fc1ccc(OCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 ZINC000073239729

ZINC000073239729 (search)

Fc1ccc(OCCCN2CCN(c3ccccc3)CC2)cc1 ZINC000033886091

ZINC000033886091 (search)

Fc1ccc(CCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 ZINC000073240518

ZINC000073240518 (search)

Fc1ccc(SCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 ZINC000073239724

ZINC000073239724 (search)

OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCSc1ccc(F)cc1 ZINC000299829856

ZINC000299829856 (search)

COc1cccc(C(=O)NCCN2CCN(c3ccc(C)cc3)CC2)c1 ZINC000013492651

ZINC000013492651 (search)

OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCCc1ccc(F)cc1 ZINC000073199171

ZINC000073199171 (search)

O[C@]1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCCc1ccc(F)cc1 ZINC000254136483

ZINC000254136483 (search)

Fc1ccc(OCCCN2CCC(c3ccc(Cl)cc3)CC2)cc1 ZINC000073239717

ZINC000073239717 (search)

O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 ZINC000000537822

ZINC000000537822 (search)

COc1cccc(C(=O)NCCN2CCN(c3ccc(Cl)cn3)CC2)c1 ZINC000027650357

ZINC000027650357 (search)

O=C(CCCN1[C@H]2CC[C@H]1CC(O)(c1ccc(Cl)cc1)C2)c1ccc(F)cc1 ZINC000101023321

ZINC000101023321 (search)

FC(F)(F)c1ccc(OCCCN2CCN(c3ccccn3)CC2)cc1 ZINC000169350276

ZINC000169350276 (search)

[O-][S@@+](CCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 ZINC000169349071

ZINC000169349071 (search)

Fc1ccc2c(c1)C[C@@H](CCN1CCN(c3ccc(Cl)cc3)CC1)C2 ZINC000169350274

ZINC000169350274 (search)

Oc1cc2c(cc1O)[C@H]1c3ccccc3CN[C@@H]1CC2 ZINC000025758512

ZINC000025758512 (search)

O=C(CCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 ZINC000028394173

ZINC000028394173 (search)

Cc1ccc(N2CCN(CCCSc3ccc(F)cc3)CC2)nc1 ZINC000169350278

ZINC000169350278 (search)

Fc1ccc(SCCCN2CCN(c3ncccn3)CC2)cc1 ZINC000082158462

ZINC000082158462 (search)

Cc1ccc(N2CCN(CCCCc3ccc(F)cc3)CC2)nc1 ZINC000169350279

ZINC000169350279 (search)

OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCSc1ccccc1F ZINC000299831510

ZINC000299831510 (search)

OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCSc1cccc(F)c1 ZINC000299831545

ZINC000299831545 (search)

Clc1ccc(N2CCCN(CCCCc3nc4ccccc4s3)CC2)cc1 ZINC000073200409

ZINC000073200409 (search)

Clc1ccc(N2CCN(CCCCc3nc4ccccc4o3)CC2)cc1 ZINC000169350281

ZINC000169350281 (search)

Clc1ccc(N2CCN(CCCc3nc4ccccc4s3)CC2)cc1 ZINC000084670345

ZINC000084670345 (search)

Fc1ccc(SCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 ZINC000082155610

ZINC000082155610 (search)

N#Cc1ccc(N2CCN(CCNC(=O)c3ccc(F)cc3)CC2)cc1 ZINC000064503527

ZINC000064503527 (search)

[O-][S@+](CCCN1CCC(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 ZINC000073239720

ZINC000073239720 (search)

O=C1c2ccccc2C[C@@H]1CCN1CCN(c2ccc(Cl)cc2)CC1 ZINC000169350271

ZINC000169350271 (search)

O=C1c2ccc(F)cc2C[C@H]1CCN1CCCN(c2ccc(Cl)cc2)CC1 ZINC000073199172

ZINC000073199172 (search)

Fc1ccc(SCCCN2CCC(c3ccc(Cl)cc3)CC2)cc1 ZINC000073239714

ZINC000073239714 (search)

CCCCN1CCC(COC(=O)c2cc(Cl)c(NC)c3c2OCCO3)CC1 ZINC000064548813

ZINC000064548813 (search)

O=C(CCCN1CCC(c2ccccc2)CC1)c1nc2ccccc2s1 ZINC000084723103

ZINC000084723103 (search)

OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCOc1ccc(F)cc1 ZINC000082149909

ZINC000082149909 (search)

O[C@@]1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCOc1ccc(F)cc1 ZINC000254111036

ZINC000254111036 (search)

Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1 ZINC000052957434

ZINC000052957434 (search)

O=C(CCCN1CCN(c2ncccn2)CC1)c1nc2ccccc2s1 ZINC000084670849

ZINC000084670849 (search)

COc1cccc(C(=O)NCCN2CCN(c3ccc(C#N)cc3)CC2)c1 ZINC000064527924

ZINC000064527924 (search)

c1ccc2c(c1)CCN(CCCCc1nc3ccccc3s1)C2 ZINC000084670854

ZINC000084670854 (search)

Clc1ccc(N2CCN(CCCc3cc4ccccc4o3)CC2)cc1 ZINC000169350284

ZINC000169350284 (search)

Fc1ccc(SCCCN2CCN(c3ccc(C(F)(F)F)cc3)CC2)cc1 ZINC000073239727

ZINC000073239727 (search)

O=C(CCCCN1CCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1 ZINC000084714700

ZINC000084714700 (search)

O=C(CCCCN1CCN(c2ccccc2)CC1)c1nc2ccccc2s1 ZINC000084706553

ZINC000084706553 (search)

Fc1ccc(OCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 ZINC000073199173

ZINC000073199173 (search)

Fc1ccc(CCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 ZINC000073197118

ZINC000073197118 (search)

O=C(CCCN1CCCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1 ZINC000082151621

ZINC000082151621 (search)

OC1(c2ccc(Cl)cc2)CCN(CCCCc2nc3ccccc3s2)CC1 ZINC000084725875

ZINC000084725875 (search)

c1ccc2c(c1)CN(CCCCc1nc3ccccc3s1)C2 ZINC000084724324

ZINC000084724324 (search)

Clc1ccc(N2CCN(CCCc3nc4ccccc4o3)CC2)cc1 ZINC000169350445

ZINC000169350445 (search)

O=C(CCCCN1CCC2(CC1)C(=O)NCN2c1ccccc1)c1nc2ccccc2s1 ZINC000084713688

ZINC000084713688 (search)

O=C(CCCCN1CCC(c2ccccc2)CC1)c1nc2ccccc2s1 ZINC000084706624

ZINC000084706624 (search)

Clc1ccc(N2CCCN(CCCc3cc4ccccc4o3)CC2)cc1 ZINC000169350287

ZINC000169350287 (search)

Clc1ccc(N2CCN(CCCCCc3nc4ccccc4o3)CC2)cc1 ZINC000169350280

ZINC000169350280 (search)

Clc1ccc(N2CCN(CCc3cc4ccccc4o3)CC2)cc1 ZINC000169350283

ZINC000169350283 (search)

CCCCN1CCC(COC(=O)c2cc(F)c(N)c3c2OCCO3)CC1 ZINC000064548828

ZINC000064548828 (search)

O=C(CCCN1CCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1 ZINC000084713683

ZINC000084713683 (search)

O=C(CCCCN1CCN(c2ncccn2)CC1)c1nc2ccccc2s1 ZINC000084714702

ZINC000084714702 (search)

Clc1ccc(N2CCCN(CCCc3nc4ccccc4s3)CC2)cc1 ZINC000073200411

ZINC000073200411 (search)

O[C@]1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCCc1nc2ccccc2s1 ZINC000254136494

ZINC000254136494 (search)

O=C(CCCCN1[C@H]2CC[C@@H]1C[C@@](O)(c1ccc(Cl)cc1)C2)c1nc2ccccc2s1 ZINC000254136488

ZINC000254136488 (search)

O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1 ZINC000084669756

ZINC000084669756 (search)

O=C(CCCCN1CCCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1 ZINC000082151618

ZINC000082151618 (search)

CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 ZINC000064548966

ZINC000064548966 (search)

Clc1ccc(N2CCN(CCc3nc4ccccc4o3)CC2)cc1 ZINC000169350282

ZINC000169350282 (search)

O=C(CCCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1)c1nc2ccccc2s1 ZINC000084670850

ZINC000084670850 (search)

Clc1ccc(N2C[C@H]3C[C@@H]2CN3CCCc2cc3ccccc3o2)cc1 ZINC000169350285

ZINC000169350285 (search)

COc1ccc(N2CCN(CC[C@H]3OCCc4ccccc43)CC2)cc1 ZINC000003812551

ZINC000003812551 (search)

COc1ccc(N2CCN(CC[C@@H]3OCCc4ccccc43)CC2)cc1 ZINC000004618051

ZINC000004618051 (search)

Fc1ccc(N2CCN(CC[C@H]3OCCc4ccccc43)CC2)cc1 ZINC000003812549

ZINC000003812549 (search)

NS(=O)(=O)c1ccc(N2CCN(CC[C@@H]3OCCc4ccccc43)CC2)cc1 ZINC000003812548

ZINC000003812548 (search)

Oc1ccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)nc1 ZINC000033996286

ZINC000033996286 (search)

Cc1ccc2c(c1)C(N1CCN(C)CC1)=Nc1cccnc1N2 ZINC000053151333

ZINC000053151333 (search)

COc1cc2c(cc1OC)[C@H](CCN1CCN(c3ccc(F)cc3)CC1)OCC2 ZINC000013756581

ZINC000013756581 (search)

Cc1cccc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 ZINC000035075419

ZINC000035075419 (search)

Cc1cccc(C(=O)NCN2CCC(c3cccc[n+]3[O-])CC2)c1 ZINC000035075418

ZINC000035075418 (search)

Cc1cc(F)ccc1NC(=O)CN1CCC(c2cccc[n+]2[O-])CC1 ZINC000035075422

ZINC000035075422 (search)

NS(=O)(=O)c1ccc(N2CCN(CC[C@H]3OCCc4ccccc43)CC2)cc1 ZINC000005162669

ZINC000005162669 (search)

COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 ZINC000003917109

ZINC000003917109 (search)

O=C(NCCCCN1CCN2c3ccccc3CC[C@H]2C1)c1ccc2ccccc2c1 ZINC000001554005

ZINC000001554005 (search)

O=C(CCCN1CCN2c3ccccc3CC[C@H]2C1)c1ccc(F)cc1 ZINC000005162674

ZINC000005162674 (search)

COc1cccc2c1N1CCN(CCCCNC(=O)c3ccc4ccccc4c3)C[C@H]1CC2 ZINC000013643297

ZINC000013643297 (search)

COc1cccc2cc(C(=O)NCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)oc12 ZINC000013492671

ZINC000013492671 (search)

O=C(NCCCCN1CCN2c3ccccc3CC[C@@H]2C1)c1ccc2ccccc2c1 ZINC000003988538

ZINC000003988538 (search)

COc1cccc2c1CC[C@@H]1CN(CCCCNC(=O)c3ccc4ccccc4c3)CCN21 ZINC000013643282

ZINC000013643282 (search)

COc1cccc2c1CC[C@H]1CN(CCCCNC(=O)c3ccc4ccccc4c3)CCN21 ZINC000013643284

ZINC000013643284 (search)

COc1c(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)ccc2ccccc12 ZINC000013492664

ZINC000013492664 (search)

COc1ccc2c(c1)N1CCN(CCCCNC(=O)c3ccc4ccccc4c3)C[C@@H]1CC2 ZINC000013643295

ZINC000013643295 (search)

COc1ccc2c(c1)N1CCN(CCCCNC(=O)c3ccc4ccccc4c3)C[C@H]1CC2 ZINC000013643293

ZINC000013643293 (search)

N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C(N)=O)cc5c4)CC3)c2c1 ZINC000001542113

ZINC000001542113 (search)