EIF2AK3

Reference Set (91 Compounds)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(Cl)c2)c2c(N)ncnc21 ZINC000095552680

ZINC000095552680 (search)

Cc1ccccc1CC(=O)N1CCc2cc(-c3cn(C)c4ncnc(N)c34)ccc21 ZINC000095554804

ZINC000095554804 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(F)c2)c2c(N)ncnc21 ZINC000095556637

ZINC000095556637 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cc(F)cc(F)c2F)c2c(N)ncnc21 ZINC000095557278

ZINC000095557278 (search)

Cc1cccc(CC(=O)N2CCc3cc(-c4cn(C)c5ncnc(N)c45)ccc32)c1 ZINC000095557724

ZINC000095557724 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cc(F)cc(C(F)(F)F)c2)c2c(N)ncnc21 ZINC000077293197

ZINC000077293197 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)c2)c2c(N)ncnc21 ZINC000095550949

ZINC000095550949 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cc(F)ccc2F)c2c(N)ncnc21 ZINC000095557715

ZINC000095557715 (search)

COc1cccc(CC(=O)N2CCc3cc(-c4cn(C)c5ncnc(N)c45)ccc32)c1 ZINC000095553435

ZINC000095553435 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2ccccc2F)c2c(N)ncnc21 ZINC000095554599

ZINC000095554599 (search)

Nc1ncc(-c2cn[nH]c2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12 ZINC000095552277

ZINC000095552277 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2ccccc2Cl)c2c(N)ncnc21 ZINC000095556640

ZINC000095556640 (search)

Nc1ncc(-c2ccncc2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12 ZINC000095552258

ZINC000095552258 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2ccc(F)cc2)c2c(N)ncnc21 ZINC000095552687

ZINC000095552687 (search)

Nc1ncc(C2CCNCC2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12 ZINC000095556178

ZINC000095556178 (search)

Nc1ncc(-c2cccnc2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12 ZINC000095555484

ZINC000095555484 (search)

Oc1cccc2cc(Nc3c(-c4ncccn4)oc4cnccc34)ccc12 ZINC000034891450

ZINC000034891450 (search)

Cn1nc(-c2ccc3c(c2)CCN3C(=O)Cc2cc(F)ccc2F)c2c(N)ncnc21 ZINC000095552305

ZINC000095552305 (search)

Nc1ncnc2scc(-c3ccc(NC(=O)Cc4cc(F)ccc4F)cc3)c12 ZINC000095552987

ZINC000095552987 (search)

CN1CCN(Cc2cnc(-c3oc4cnccc4c3Nc3ccc4c(O)cccc4c3)nc2)CC1 ZINC000066073613

ZINC000066073613 (search)

Cc1ccc(CC(=O)N2CCc3cc(-c4cn(C)c5ncnc(N)c45)ccc32)cc1 ZINC000095554579

ZINC000095554579 (search)

O/N=C1\NCc2cc(Nc3c(-c4ncccn4)oc4cnccc34)ccc21 ZINC000066075021

ZINC000066075021 (search)

CCOC(=O)c1oc2cnccc2c1Nc1ccc2c(c1)CC/C2=N/O ZINC000101393876

ZINC000101393876 (search)

Oc1cc(Nc2c(-c3ncccn3)oc3cnccc23)ccc1Cl ZINC000064746574

ZINC000064746574 (search)

O=C(Nc1ccncn1)c1oc2cnccc2c1Nc1ccc2c(O)cccc2c1 ZINC000034891276

ZINC000034891276 (search)

CCOC(=O)c1oc2cnccc2c1Nc1ccc2c(O)cccc2c1 ZINC000034892054

ZINC000034892054 (search)

CC(C)NC(=O)c1oc2cnccc2c1Nc1ccc2c(O)cccc2c1 ZINC000034892204

ZINC000034892204 (search)

CN(C)/C=C/NC(=O)c1oc2cnccc2c1Nc1ccc2c(O)cccc2c1 ZINC000101394974

ZINC000101394974 (search)

CCc1n[nH]c2c(Cl)ccc(Nc3c(-c4ncccn4)oc4cnccc34)c12 ZINC000066078674

ZINC000066078674 (search)

CCOC(=O)c1oc2cnccc2c1Nc1ccc2c(O)c(F)ccc2c1 ZINC000034891984

ZINC000034891984 (search)

Clc1ccc(Nc2c(-c3ncccn3)oc3cnccc23)c2cn[nH]c12 ZINC000066079408

ZINC000066079408 (search)

Cc1cc(Nc2c(-c3ncccn3)oc3cnccc23)c2cn[nH]c2c1Cl ZINC000066074453

ZINC000066074453 (search)

OCCCc1n[nH]c2c(Cl)ccc(Nc3c(-c4ncccn4)oc4cnccc34)c12 ZINC000066078677

ZINC000066078677 (search)

CCOC(=O)c1oc2cnccc2c1Nc1ccc(Cl)c(O)c1 ZINC000066073614

ZINC000066073614 (search)

O=C(Nc1ncccn1)c1oc2cnccc2c1Nc1ccc(Cl)c(O)c1 ZINC000066073616

ZINC000066073616 (search)

O=C1CCc2cc(Nc3c(-c4ncccn4)oc4cnccc34)ccc21 ZINC000034891451

ZINC000034891451 (search)

CC(C)NC(=O)c1oc2cnccc2c1Nc1ccc(Cl)c(O)c1 ZINC000066073615

ZINC000066073615 (search)

Cc1ccc(Nc2c(-c3ncccn3)oc3cnccc23)c2cn[nH]c12 ZINC000066074451

ZINC000066074451 (search)

c1cnc(-c2oc3cnccc3c2Nc2ccc3c(c2)Cc2c[nH]nc2-3)nc1 ZINC000066075028

ZINC000066075028 (search)

CC(C)NC(=O)c1oc2cnccc2c1Nc1ccc2c(c1)CN/C2=N\O ZINC000066074373

ZINC000066074373 (search)

NCCCc1n[nH]c2c(Cl)ccc(Nc3c(-c4ncccn4)oc4cnccc34)c12 ZINC000066078675

ZINC000066078675 (search)

Clc1cc(Nc2c(-c3ncccn3)oc3cnccc23)c2cn[nH]c2c1 ZINC000066079410

ZINC000066079410 (search)

c1cnc(-c2oc3cnccc3c2Nc2cccc3[nH]ncc23)nc1 ZINC000066165807

ZINC000066165807 (search)

Fc1ccc(Nc2c(-c3ncccn3)oc3cnccc23)c2cn[nH]c12 ZINC000066074452

ZINC000066074452 (search)

CC(C)NC(=O)c1oc2cnccc2c1Nc1ccc(Cl)c2[nH]ncc12 ZINC000066074450

ZINC000066074450 (search)

CN/C=C/NC(=O)c1oc2cnccc2c1Nc1ccc2c(c1)Cc1c[nH]nc1-2 ZINC000101395024

ZINC000101395024 (search)

CCOC(=O)c1oc2cnccc2c1Nc1cnc2ccccc2c1 ZINC000066098481

ZINC000066098481 (search)

CCOC(=O)c1oc2cnccc2c1Nc1ccc2c(c1)CCC2=O ZINC000066075018

ZINC000066075018 (search)

CC(C)NC(=O)c1oc2cnccc2c1Nc1ccc2c(c1)Cc1c[nH]nc1-2 ZINC000066075023

ZINC000066075023 (search)

CCOC(=O)c1oc2cnccc2c1Nc1ccc2c(N)cccc2c1 ZINC000034891982

ZINC000034891982 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3cc(F)ccc3F)c2cc1OC ZINC000299830572

ZINC000299830572 (search)

Cn1cc(-c2ccc3c(c2F)CCN3C(=O)Cc2cccc(C(F)(F)F)n2)c2c(N)ncnc21 ZINC000096285831

ZINC000096285831 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)n2)c2c(N)ncnc21 ZINC000096285834

ZINC000096285834 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3c(C)[nH]c4cc(F)ccc34)c2cc1OC ZINC000299836449

ZINC000299836449 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3c(C)[nH]c4ccccc34)c2cc1OC ZINC000219437901

ZINC000219437901 (search)

Cc1cccc(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1 ZINC000096170461

ZINC000096170461 (search)

Cn1cc(-c2ccc3c(c2)CCN3CC(=O)c2cc(F)cc(C(F)(F)F)c2)c2c(N)ncnc21 ZINC000097974823

ZINC000097974823 (search)

COc1cc2ncnc(Nc3ccc4c(c3F)CCN4C(=O)Cc3c(C)[nH]c4ccccc34)c2cc1OC ZINC000219438016

ZINC000219438016 (search)

CNc1ncc2ccc(Oc3cc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)ccc3C)cc2n1 ZINC000299867635

ZINC000299867635 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3c(C)[nH]c4c(F)cccc34)c2cc1OC ZINC000299819629

ZINC000299819629 (search)

Cc1cc(C)n(CC(=O)N2CCc3cc(-c4cn(C)c5ncnc(N)c45)ccc32)n1 ZINC000096285833

ZINC000096285833 (search)

Cc1nc(N)c2c(-c3ccc4c(c3)CCN4CC(=O)c3cc(F)cc(C(F)(F)F)c3)cn(C)c2n1 ZINC000299865876

ZINC000299865876 (search)

Cc1cccc(CC(=O)N2CCc3cc(-c4cn(C)c5ncnc(N)c45)ccc32)n1 ZINC000096285835

ZINC000096285835 (search)

Cc1cc(C)n(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1 ZINC000096285832

ZINC000096285832 (search)

CNc1ncc2ccc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1 ZINC000299854907

ZINC000299854907 (search)

CNc1ncc2ccc(Oc3cc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)ccc3N)cc2n1 ZINC000299862154

ZINC000299862154 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cn3c(C)cc4ccc(F)cc43)c2cc1OC ZINC000219452948

ZINC000219452948 (search)

Cc1nc2ccc(-c3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2s1 ZINC000299857398

ZINC000299857398 (search)

CNc1ncc2c(F)cc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1 ZINC000299862879

ZINC000299862879 (search)

COc1cc2nccc(Oc3ccc(NC(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)nc3)c2cc1OC ZINC000299867093

ZINC000299867093 (search)

CNc1ncc2ccc(Oc3cc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)ccc3Cl)cc2n1 ZINC000299864060

ZINC000299864060 (search)

Cc1ncc2ccc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1 ZINC000299871607

ZINC000299871607 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3c[nH]c4ccccc34)c2cc1OC ZINC000299819604

ZINC000299819604 (search)

Cc1ccc2cc(-c3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)ccc2n1 ZINC000223063193

ZINC000223063193 (search)

Cc1ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c(N)c1-c1ccc2nc(CF)sc2c1 ZINC000299863045

ZINC000299863045 (search)

CNc1ncc2c(Cl)cc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1 ZINC000299864586

ZINC000299864586 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cn3ccc4ccccc43)c2cc1OC ZINC000299838881

ZINC000299838881 (search)

CNc1nc2ccc(-c3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2s1 ZINC000223063093

ZINC000223063093 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3coc4ccccc34)c2cc1OC ZINC000299835053

ZINC000299835053 (search)

Cc1ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c(N)c1-c1ccc2nc(N)sc2c1 ZINC000299860341

ZINC000299860341 (search)

Cc1ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c(N)c1-c1ccc2nc(C(F)F)sc2c1 ZINC000299868919

ZINC000299868919 (search)

Cc1ccnn1CC(=O)N1CCc2cc(-c3cn(C)c4ncnc(N)c34)ccc21 ZINC000096285836

ZINC000096285836 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2ccccn2)c2c(N)ncnc21 ZINC000096285840

ZINC000096285840 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccnc2)c2c(N)ncnc21 ZINC000096285839

ZINC000096285839 (search)

CNc1ncc2cc(-c3c(C)ccc(C(=O)Nc4ccc(OC)c(C(F)(F)F)c4)c3N)ccc2n1 ZINC000223062923

ZINC000223062923 (search)

COc1cc2nccc(Oc3ccc(NC(=O)c4c(-c5ccncc5)n(C)n(-c5ccccc5)c4=O)nc3)c2cc1OC ZINC000113299168

ZINC000113299168 (search)

Cc1ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c(N)c1-c1ccc2nc(C(F)(F)F)sc2c1 ZINC000299858538

ZINC000299858538 (search)

Cc1ccn(CC(=O)N2CCc3cc(-c4cn(C)c5ncnc(N)c45)ccc32)n1 ZINC000096285837

ZINC000096285837 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2ccncc2)c2c(N)ncnc21 ZINC000096285838

ZINC000096285838 (search)

Cc1nc2cc(-c3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)ccc2s1 ZINC000299859214

ZINC000299859214 (search)

COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3ccn(C)n3)c2cc1OC ZINC000299841047

ZINC000299841047 (search)