Results of Job: search_e8dc570e-cfc1-4ca2-a854-9d8e6a8d30fc

Query Target Key Target Name Description P-Value MaxTC

quercetin

AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 2.9e-124 1.00
DDL_HELPH ddl D-alanine--D-alanine ligase 2.9e-124 1.00
O96394_LEIAM Arginase 4.471e-100 1.00
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 3.073e-96 1.00
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.593e-95 1.00
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 2.562e-88 1.00
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.714e-79 1.00
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.358e-45 1.00
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 4.279e-45 1.00
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 5.18e-44 1.00
R1AB_SARS rep Replicase polyprotein 1ab 1.704e-37 1.00
MDH_THETH mdh Malate dehydrogenase 3.937e-30 1.00
PERL_BOVIN LPO Lactoperoxidase 3.937e-30 1.00
NANH_CLOPF nanH Sialidase 4.566e-29 1.00
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.301e-28 1.00
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 3.59e-28 1.00
NOX4_HUMAN NOX4 NADPH oxidase 4 1.561e-25 1.00
LGUL_HUMAN GLO1 Lactoylglutathione lyase 4.545e-24 1.00
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 9.163e-22 1.00
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 1.344e-21 1.00
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.176e-19 1.00
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.443e-18 1.00
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 3.874e-18 1.00
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 8.364e-18 1.00
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.11e-16 1.00
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 1.887e-15 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.475e-14 1.00
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 7.329e-13 1.00
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.337e-12 1.00
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.589e-12 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.392e-11 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.122e-11 1.00
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 2.255e-11 1.00
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 2.435e-11 1.00
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 6.82e-11 1.00
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 6.845e-11 1.00
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.105e-10 1.00
5NTD_RAT Nt5e 5'-nucleotidase 2.504e-10 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.172e-08 1.00
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.441e-08 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.711e-08 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.034e-07 1.00
PERM_HUMAN MPO Myeloperoxidase 1.309e-07 1.00
B4URF0_I33A0 Neuraminidase 2.531e-07 1.00
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 2.778e-07 1.00
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 6.112e-07 1.00
A4_HUMAN APP Amyloid-beta precursor protein 1.268e-06 1.00
AMPC_ECOLI ampC Beta-lactamase 2.404e-06 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.532e-05 1.00
PA21B_HUMAN PLA2G1B Phospholipase A2 0.0002226 1.00
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 0.0002684 1.00
AA1R_RAT Adora1 Adenosine receptor A1 0.0002815 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 0.0003039 1.00
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 0.0009832 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 0.0009832 1.00
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 0.001074 1.00
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 0.001483 1.00
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 0.002251 1.00
AA2AR_RAT Adora2a Adenosine receptor A2a 0.003137 1.00
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 0.005973 1.00
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 0.007685 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 0.01269 1.00
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 0.01865 1.00
TRY1_BOVIN Cationic trypsin 0.02371 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 0.02729 1.00
V2R_HUMAN AVPR2 Vasopressin V2 receptor 0.0297 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.08587 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.09505 1.00
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 0.1025 1.00
AURKB_HUMAN AURKB Aurora kinase B 0.1205 1.00
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 0.1593 1.00
BACE1_HUMAN BACE1 Beta-secretase 1 0.2119 1.00
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 0.2183 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 0.2708 1.00
ALK_HUMAN ALK ALK tyrosine kinase receptor 0.2734 1.00
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 0.4105 1.00
PIM1_HUMAN PIM1 Serine/threonine-protein kinase pim-1 0.4143 1.00
FAK1_HUMAN PTK2 Focal adhesion kinase 1 0.4508 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.5125 1.00
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 0.5833 1.00
MMP3_HUMAN MMP3 Stromelysin-1 0.5921 1.00
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 0.6409 1.00
MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.6846 1.00
MET_HUMAN MET Hepatocyte growth factor receptor 0.7762 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.8162 1.00
MMP13_HUMAN MMP13 Collagenase 3 0.8636 1.00
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 0.8909 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.9429 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 0.9795 1.00
THRB_HUMAN F2 Prothrombin 0.9968 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 0.9993 1.00
VE6_HPV16 E6 Protein E6 1.679e-112 0.76
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 2.97e-94 0.76
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 2.974e-79 0.60
TOP1_RAT Top1 DNA topoisomerase 1 2.514e-74 0.60
FAS_CHICK FASN Fatty acid synthase 3.487e-68 0.55
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.639e-59 0.72
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 4.676e-55 0.67
BGLR_RAT Gusb Beta-glucuronidase 2.038e-54 0.48
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 3.773e-53 0.67
OPRD_PIG OPRD1 Delta-type opioid receptor 1.658e-48 0.39
ARGI1_RAT Arg1 Arginase-1 1.509e-47 0.60
SYN1_BOVIN SYN1 Synapsin-1 4.792e-44 0.72
PDIA1_HUMAN P4HB Protein disulfide-isomerase 4.362e-43 0.58
CBS_HUMAN CBS Cystathionine beta-synthase 3.733e-36 0.37
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 4.527e-34 0.67
LYSC1_RAT Lyz1 Lysozyme C-1 2.939e-33 0.41
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.437e-32 0.40
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.086e-29 0.29
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 1.816e-20 0.33
PLGF_HUMAN PGF Placenta growth factor 4.473e-20 0.39
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.575e-19 0.38
Q7ZJM1_9HIV1 pol Integrase 3.817e-19 0.76
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 5.576e-19 0.30
PON1_HUMAN PON1 Serum paraoxonase/arylesterase 1 6.741e-19 0.30
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 9.981e-19 0.60
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 7.495e-18 0.41
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.038e-17 0.43
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.11e-16 0.42
SYUA_HUMAN SNCA Alpha-synuclein 2.22e-16 0.37
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.11e-15 0.60
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.22e-15 0.49
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 4.552e-15 0.72
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 4.319e-13 0.42
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.117e-12 0.76
REST_BORBU resT Telomere resolvase ResT 6.139e-12 0.29
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 7.536e-12 0.55
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.105e-11 0.41
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 3.304e-11 0.55
TERT_HUMAN TERT Telomerase reverse transcriptase 1.915e-10 0.44
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 3.547e-10 0.32
ESR2_HUMAN ESR2 Estrogen receptor beta 1.072e-09 0.48
DHPR_RAT Qdpr Dihydropteridine reductase 2.944e-09 0.31
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 4.147e-09 0.38
TAU_HUMAN MAPT Microtubule-associated protein tau 4.285e-09 0.76
DHPR_HUMAN QDPR Dihydropteridine reductase 9.718e-09 0.31
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.811e-08 0.38
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.431e-08 0.66
DPO1_THEAQ polA DNA polymerase I, thermostable 3.257e-08 0.34
TTHY_HUMAN TTR Transthyretin 9.297e-08 0.60
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.057e-07 0.60
Q43570_TOBAC NtBBF1.1 Zn finger protein 2.996e-07 0.30
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 3.025e-07 0.60
IL2_HUMAN IL2 Interleukin-2 5.605e-07 0.37
IL5_MOUSE Il5 Interleukin-5 5.605e-07 0.37
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 7.579e-07 0.39
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 8.573e-07 0.48
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 1.204e-06 0.41
ESR1_HUMAN ESR1 Estrogen receptor 1.446e-06 0.48
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 6.733e-06 0.60
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 6.783e-06 0.76

isorhamnetin

Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 6.695e-81 1.00
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.138e-66 1.00
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 1.185e-37 1.00
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.603e-27 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.674e-18 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.077e-14 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.15e-08 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.003998 1.00
VE6_HPV16 E6 Protein E6 2.638e-94 0.61
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 7.815e-90 0.72
DDL_HELPH ddl D-alanine--D-alanine ligase 7.815e-90 0.72
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 3.099e-79 0.72
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 6.697e-78 0.72
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 1.35e-76 0.61
O96394_LEIAM Arginase 3.853e-75 0.72
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 5.038e-67 0.73
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 9.123e-61 0.34
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.093e-57 0.72
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.191e-57 0.43
FAS_CHICK FASN Fatty acid synthase 1.011e-55 0.44
TOP1_RAT Top1 DNA topoisomerase 1 4.144e-54 0.43
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 1.143e-52 0.37
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.893e-50 0.72
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 1.503e-48 0.35
BGLR_RAT Gusb Beta-glucuronidase 4.197e-48 0.42
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 3.533e-46 0.58
OPRD_PIG OPRD1 Delta-type opioid receptor 5.686e-44 0.35
PDIA1_HUMAN P4HB Protein disulfide-isomerase 3.012e-41 0.55
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 8.889e-39 0.32
CBS_HUMAN CBS Cystathionine beta-synthase 1.331e-37 0.40
LRP6_HUMAN LRP6 Low-density lipoprotein receptor-related protein 6 1.627e-36 0.30
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 2.896e-35 0.58
ARGI1_RAT Arg1 Arginase-1 1.073e-34 0.43
R1AB_SARS rep Replicase polyprotein 1ab 3.316e-34 0.72
SYN1_BOVIN SYN1 Synapsin-1 3.476e-32 0.52
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.619e-32 0.72
NANH_CLOPF nanH Sialidase 5.487e-30 0.72
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.223e-29 0.58
LYSC1_RAT Lyz1 Lysozyme C-1 1.607e-29 0.37
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 4.233e-29 0.29
DHPR_HUMAN QDPR Dihydropteridine reductase 2.76e-27 0.35
LGUL_HUMAN GLO1 Lactoylglutathione lyase 3.681e-27 0.72
TLR1_MOUSE Tlr1 Toll-like receptor 1 2.665e-26 0.30
TLR2_MOUSE Tlr2 Toll-like receptor 2 2.665e-26 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.039e-25 0.72
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 2.847e-23 0.29
TAU_HUMAN MAPT Microtubule-associated protein tau 5.303e-22 0.61
MDH_THETH mdh Malate dehydrogenase 6.089e-22 0.72
PERL_BOVIN LPO Lactoperoxidase 6.089e-22 0.72
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.186e-21 0.72
NOX4_HUMAN NOX4 NADPH oxidase 4 2.863e-21 0.74
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.583e-20 0.72
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 3.355e-20 0.47
DHPR_RAT Qdpr Dihydropteridine reductase 1.037e-19 0.35
MTSI_SPISQ sssIM CPG DNA methylase 2.724e-19 0.32
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.06e-19 0.76
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 3.357e-19 0.48
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.372e-18 0.29
PLGF_HUMAN PGF Placenta growth factor 3.043e-18 0.35
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.882e-17 0.33
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.102e-17 0.38
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 1.11e-16 0.72
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 5.551e-16 0.50
Q7ZJM1_9HIV1 pol Integrase 5.551e-16 0.67
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 6.661e-16 0.72
CAH13_HUMAN CA13 Carbonic anhydrase 13 8.882e-16 0.39
ACES_RAT Ache Acetylcholinesterase 1.998e-15 0.40
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 2.776e-15 0.72
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 4.219e-15 0.35
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 6.883e-15 0.34
DCOR_HUMAN ODC1 Ornithine decarboxylase 9.215e-15 0.29
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.732e-14 0.60
A4_HUMAN APP Amyloid-beta precursor protein 1.776e-14 0.72
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.787e-14 0.72
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 3.497e-14 0.72
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 4.774e-14 0.42
Q43570_TOBAC NtBBF1.1 Zn finger protein 7.86e-14 0.31
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.215e-13 0.43
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.823e-13 0.72
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.311e-13 0.43
REST_BORBU resT Telomere resolvase ResT 2.428e-13 0.33
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.803e-13 0.72
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 3.025e-13 0.72
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 7.476e-13 0.31
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 7.555e-13 0.44
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 3.617e-12 0.72
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 2.428e-11 0.30
IL2_HUMAN IL2 Interleukin-2 2.632e-11 0.33
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 5.058e-11 0.44
CAN_CANAL NCE103 Carbonic anhydrase 8.305e-11 0.38
ESR2_HUMAN ESR2 Estrogen receptor beta 9.47e-11 0.46
ITF2_HUMAN TCF4 Transcription factor 4 1.522e-10 0.28
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.92e-10 0.32
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 2.424e-10 0.33
O96526_LEIMA CRK3 Cdc2-related kinase 2.659e-10 0.30
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.076e-10 0.72
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 3.547e-10 0.37
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.821e-10 0.61
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 8.226e-10 0.35
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.27e-09 0.72
Q49PX0_9POXV N1L N1L 1.557e-09 0.34
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.052e-09 0.72
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 3.157e-09 0.72
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 3.598e-09 0.29
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 4.61e-09 0.72
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.89e-09 0.72
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.965e-09 0.36
CAH3_HUMAN CA3 Carbonic anhydrase 3 5.095e-09 0.72
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 9.338e-09 0.72
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.035e-08 0.43
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 1.124e-08 0.60
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.806e-08 0.37
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 2.215e-08 0.72
TTHY_HUMAN TTR Transthyretin 2.223e-08 0.43
GPR35_HUMAN GPR35 G-protein coupled receptor 35 2.224e-08 0.72
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 2.995e-08 0.33
ESR1_HUMAN ESR1 Estrogen receptor 3.059e-08 0.42
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 3.257e-08 0.34
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 3.414e-08 0.72
TERT_HUMAN TERT Telomerase reverse transcriptase 3.929e-08 0.36
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 4.164e-08 0.39
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 5.032e-08 0.31
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 5.593e-08 0.72
5NTD_RAT Nt5e 5'-nucleotidase 1.271e-07 0.72
SHBG_HUMAN SHBG Sex hormone-binding globulin 5.047e-07 0.32
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 5.652e-07 0.72
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 6.995e-07 0.72
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 7.249e-07 0.37
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 9.959e-07 0.61
FOS_HUMAN FOS Proto-oncogene c-Fos 9.992e-07 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.002e-06 0.39
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.699e-06 0.61
IL5_MOUSE Il5 Interleukin-5 1.998e-06 0.34
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 2.91e-06 0.35
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 3.143e-06 0.43
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.563e-06 0.28
PERM_HUMAN MPO Myeloperoxidase 4.036e-06 0.72
DPP4_PIG DPP4 Dipeptidyl peptidase 4 4.382e-06 0.41
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 4.641e-06 0.42
B4URF0_I33A0 Neuraminidase 7.776e-06 0.72
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 7.85e-06 0.28
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 9.24e-06 0.42

acacetin

CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.563e-74 1.00
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 4.629e-39 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.588e-14 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 4.709e-12 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.153e-05 1.00
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 0.000167 1.00
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 0.0003225 1.00
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 0.005816 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.02602 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.1181 1.00
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 8.876e-94 0.53
TOP1_RAT Top1 DNA topoisomerase 1 3.871e-83 0.67
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 2.475e-77 0.67
OPRD_PIG OPRD1 Delta-type opioid receptor 2.142e-68 0.55
BGLR_RAT Gusb Beta-glucuronidase 1.205e-65 0.74
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.833e-64 0.74
ACES_RAT Ache Acetylcholinesterase 5.728e-62 0.49
VE6_HPV16 E6 Protein E6 1.097e-61 0.39
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 5.742e-59 0.54
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 3.673e-58 0.67
Q0PJ46_PLAFA LDH Lactate dehydrogenase 1.545e-57 0.40
ARGI1_RAT Arg1 Arginase-1 3.773e-53 0.67
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 1.049e-52 0.42
DDL_HELPH ddl D-alanine--D-alanine ligase 1.049e-52 0.42
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 5.901e-52 0.67
O96394_LEIAM Arginase 9.873e-51 0.42
CBS_HUMAN CBS Cystathionine beta-synthase 1.517e-50 0.73
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.857e-50 0.49
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 9.973e-49 0.39
MDHC_PIG MDH1 Malate dehydrogenase, cytoplasmic 1.108e-47 0.40
Q6VVP7_PLAFA Malate dehydrogenase 1.108e-47 0.40
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 4.585e-43 0.39
FAS_CHICK FASN Fatty acid synthase 5.166e-42 0.33
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 6.014e-38 0.74
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.86e-35 0.74
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 8.367e-34 0.42
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 7.094e-33 0.41
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 7.094e-33 0.41
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.353e-33 0.63
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.828e-31 0.39
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.909e-31 0.52
HSC82_YEAST HSC82 ATP-dependent molecular chaperone HSC82 4.54e-31 0.31
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 4.705e-31 0.74
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.468e-30 0.36
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 9.56e-30 0.74
PLGF_HUMAN PGF Placenta growth factor 4.107e-28 0.55
DPO1_THEAQ polA DNA polymerase I, thermostable 6.251e-28 0.59
AMY1A_HUMAN AMY1A Alpha-amylase 1 2.011e-27 0.53
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 4.301e-27 0.48
LYSC1_RAT Lyz1 Lysozyme C-1 5.245e-27 0.33
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 1.407e-26 0.33
ACES_ELEEL ache Acetylcholinesterase 2.684e-26 0.44
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 9.509e-26 0.74
PERL_BOVIN LPO Lactoperoxidase 4.343e-25 0.42
Q9X688_CAUVI cckA Cell cycle histidine kinase CckA 8.615e-25 0.31
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 9.908e-25 0.56
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 1.132e-24 0.30
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 1.19e-24 0.40
R1AB_SARS rep Replicase polyprotein 1ab 7.439e-24 0.55
A4_HUMAN APP Amyloid-beta precursor protein 1.112e-21 0.67
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.461e-21 0.74
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.876e-21 0.42
IL2_HUMAN IL2 Interleukin-2 2.776e-20 0.44
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 3.642e-20 0.39
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.854e-20 0.40
NOX4_HUMAN NOX4 NADPH oxidase 4 8.107e-20 0.74
ESR2_HUMAN ESR2 Estrogen receptor beta 2.035e-19 0.74
PON1_HUMAN PON1 Serum paraoxonase/arylesterase 1 2.322e-19 0.31
CALM1_HUMAN CALM1 Calmodulin-1 2.482e-19 0.39
EF1A1_HUMAN EEF1A1 Elongation factor 1-alpha 1 6.741e-19 0.30
EF1A2_HUMAN EEF1A2 Elongation factor 1-alpha 2 6.741e-19 0.30
SYN1_BOVIN SYN1 Synapsin-1 1.126e-18 0.30
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 1.016e-17 0.39
I3LTK9_PIG CEL Carboxylic ester hydrolase 4.334e-17 0.29
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 5.231e-17 0.68
REST_BORBU resT Telomere resolvase ResT 5.404e-17 0.42
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 2.22e-16 0.31
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 3.331e-16 0.67
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 7.772e-16 0.67
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 9.992e-16 0.58
ESR1_HUMAN ESR1 Estrogen receptor 2.331e-15 0.74
LGUL_HUMAN GLO1 Lactoylglutathione lyase 2.554e-15 0.67
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 5.329e-15 0.42
CAH7_HUMAN CA7 Carbonic anhydrase 7 8.993e-15 0.67
CAH3_HUMAN CA3 Carbonic anhydrase 3 9.659e-15 0.42
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.599e-14 0.47
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 2.043e-14 0.45
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 2.298e-14 0.39
CHLE_HORSE BCHE Cholinesterase 2.986e-14 0.44
P89582_9HIV2 pol Integrase 4.43e-14 0.31
AHR_HUMAN AHR Aryl hydrocarbon receptor 5.629e-14 0.39
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 6.872e-14 0.74
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 8.682e-14 0.53
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.176e-13 0.67
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 3.674e-13 0.33
MDH_THETH mdh Malate dehydrogenase 4.124e-13 0.42
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.103e-12 0.47
NANH_CLOPF nanH Sialidase 1.449e-12 0.67
Q7ZJM1_9HIV1 pol Integrase 1.708e-12 0.74
TERT_HUMAN TERT Telomerase reverse transcriptase 2.419e-12 0.59
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 2.771e-12 0.42
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 3.001e-12 0.30
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 5.569e-12 0.35
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 6.494e-12 0.51
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 1.018e-11 0.37
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.205e-11 0.43
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.423e-11 0.67
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.198e-11 0.45
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 2.51e-11 0.38
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.904e-11 0.34
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 3.732e-11 0.74
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 8.122e-11 0.42
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.117e-10 0.36
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.281e-10 0.40
FEN1_HUMAN FEN1 Flap endonuclease 1 1.284e-10 0.30
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.577e-10 0.28
ACES_HUMAN ACHE Acetylcholinesterase 1.732e-10 0.74
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.329e-10 0.74
TTHY_HUMAN TTR Transthyretin 5.029e-10 0.74
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 6.6e-10 0.31
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 8.307e-10 0.41
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.1e-09 0.47
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.202e-09 0.67
EST1_RABIT Liver carboxylesterase 1 1.311e-09 0.31
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 1.416e-09 0.42
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.752e-09 0.36
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 2.078e-09 0.55
CP19A_HUMAN CYP19A1 Aromatase 2.116e-09 0.74
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.593e-09 0.56
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 2.837e-09 0.74
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.643e-09 0.67
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.019e-09 0.31
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.313e-08 0.43
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.437e-08 0.42
DPP4_PIG DPP4 Dipeptidyl peptidase 4 1.924e-08 0.60
EGLN1_RAT Egln1 Egl nine homolog 1 3.633e-08 0.32
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 4.403e-08 0.33
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.437e-08 0.41
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 4.872e-08 0.42
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.898e-08 0.67
FACE2_HUMAN RCE1 CAAX prenyl protease 2 4.939e-08 0.38
ANDR_HUMAN AR Androgen receptor 5.124e-08 0.74
LRP6_HUMAN LRP6 Low-density lipoprotein receptor-related protein 6 5.869e-08 0.30
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 6.186e-08 0.29
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.14e-07 0.34
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.206e-07 0.67
AA1R_RAT Adora1 Adenosine receptor A1 1.282e-07 0.79
ACES_BOVIN ACHE Acetylcholinesterase 1.298e-07 0.34
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.422e-07 0.67
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.526e-07 0.38
Q43570_TOBAC NtBBF1.1 Zn finger protein 1.91e-07 0.30
FABI_ECOLI fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 2.612e-07 0.67
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.211e-07 0.42
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 3.242e-07 0.34
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.26e-07 0.42
EGFR_MOUSE Egfr Epidermal growth factor receptor 3.977e-07 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 4.192e-07 0.47
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.39e-07 0.47
PERM_HUMAN MPO Myeloperoxidase 5.48e-07 0.74
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 6.144e-07 0.50
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 7.847e-07 0.37
LUCI_PHOPY Luciferin 4-monooxygenase 9.908e-07 0.37
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.158e-06 0.42
KLK7_HUMAN KLK7 Kallikrein-7 1.242e-06 0.38
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.489e-06 0.47
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 1.567e-06 0.52
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.614e-06 0.34
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.618e-06 0.35
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 2.249e-06 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 2.366e-06 0.40
IL5_MOUSE Il5 Interleukin-5 2.417e-06 0.33
TYRO_HUMAN TYR Tyrosinase 2.862e-06 0.58
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.607e-06 0.39
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.77e-06 0.29
COMT_HUMAN COMT Catechol O-methyltransferase 3.815e-06 0.36
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 4.23e-06 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.494e-06 0.54
OXDA_MOUSE Dao D-amino-acid oxidase 5.16e-06 0.28
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 6.247e-06 0.54
SENP7_HUMAN SENP7 Sentrin-specific protease 7 6.731e-06 0.43
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 8.755e-06 0.28
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 8.851e-06 0.37
TLR1_MOUSE Tlr1 Toll-like receptor 1 9.511e-06 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 9.511e-06 0.29

(R)-Canadine

DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.267e-66 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 7.713e-25 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.071e-14 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.462e-12 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.774e-10 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.148e-05 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.0002531 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.004161 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.02376 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.06843 1.00
VE2_HPV1 E2 Regulatory protein E2 5.166e-42 0.33
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 5.542e-39 0.37
DRD1_RAT Drd1 D(1A) dopamine receptor 2.089e-36 0.65
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 5.696e-36 0.39
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 8.207e-33 0.37
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.014e-32 0.50
TF_HUMAN F3 Tissue factor 1.146e-32 0.80
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.404e-30 0.50
ACES_ELEEL ache Acetylcholinesterase 1.296e-29 0.40
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.127e-28 0.36
CHLE_HORSE BCHE Cholinesterase 6.98e-28 0.40
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 4.465e-22 0.39
Q9XSW7_PIG Phosphodiesterase 2.139e-18 0.29
ACHA2_HUMAN CHRNA2 Neuronal acetylcholine receptor subunit alpha-2 3.143e-18 0.29
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.332e-15 0.39
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 7.583e-14 0.46
DRD2_RAT Drd2 D(2) dopamine receptor 1.35e-13 0.65
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.789e-13 0.33
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 7.268e-13 0.39
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 1.714e-12 0.34
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 2.757e-12 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 4.761e-12 0.60
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 5.582e-12 0.35
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.606e-11 0.34
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 3.688e-11 0.34
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 9.837e-11 0.34
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.084e-10 0.29
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 6.212e-10 0.34
EDNRA_HUMAN EDNRA Endothelin-1 receptor 7.943e-10 0.36
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 2.37e-09 0.33
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 5.224e-09 0.34
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.504e-09 0.79
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.592e-09 0.60
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.169e-08 0.34
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.794e-08 0.69
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 4.366e-08 0.46
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.538e-08 0.61
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.208e-08 0.61
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 6.349e-08 0.41
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.528e-07 0.46
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.749e-07 0.39
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.967e-07 0.29
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.192e-07 0.30
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.066e-07 0.42
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 4.707e-07 0.30
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 6.204e-07 0.46
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.62e-06 0.35
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 1.941e-06 0.34
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 3.65e-06 0.50
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.748e-06 0.76
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 4.022e-06 0.32
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 4.325e-06 0.31
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 5.075e-06 0.28
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.234e-06 0.31
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 8.994e-06 0.29

Mairin

DPOLB_RAT Polb DNA polymerase beta 1.131e-63 1.00
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.78e-25 1.00
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.357e-17 1.00
Q9YQ12_9HIV1 protease Protease 7.147e-06 1.00
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 0.0005651 1.00
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 0.0006262 1.00
Q77YG1_9HIV1 gag Gag polyprotein 5.585e-81 0.67
CD81_HUMAN CD81 CD81 antigen 4.556e-46 0.37
DHI2_RAT Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.092e-44 0.35
Q43445_SOYBN Methyltransferase 6.705e-36 0.28
PA2A1_ECHCA Acidic phospholipase A2 EC-I 1.78e-34 0.43
PA2B1_NAJME Basic phospholipase A2 1 1.78e-34 0.43
PA2BA_PROFL Basic phospholipase A2 PLA-A 1.78e-34 0.43
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 5.786e-27 0.53
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.875e-23 0.72
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 2.073e-22 0.43
IL1B_HUMAN IL1B Interleukin-1 beta 1.122e-17 0.34
TF65_HUMAN RELA Transcription factor p65 1.11e-16 0.75
POL_HV1H2 gag-pol Gag-Pol polyprotein 5.551e-16 0.67
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.107e-15 0.35
TF_HUMAN F3 Tissue factor 4.314e-13 0.68
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.966e-10 0.60
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.45e-09 0.36
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 7.407e-08 0.32
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 9.508e-08 0.46
DPOLB_HUMAN POLB DNA polymerase beta 4.01e-07 0.43
EST2_HUMAN CES2 Cocaine esterase 4.899e-07 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.047e-06 0.43

berberine

ACES_ELEEL ache Acetylcholinesterase 9.049e-57 1.00
CHLE_HORSE BCHE Cholinesterase 2.033e-48 1.00
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.617e-08 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.08263 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.09988 1.00
CHLE_HUMAN BCHE Cholinesterase 0.4887 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.7183 1.00
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.503e-61 0.77
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.819e-40 0.48
VE2_HPV1 E2 Regulatory protein E2 1.215e-35 0.28
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 4.212e-24 0.30
RGS17_HUMAN RGS17 Regulator of G-protein signaling 17 2.952e-20 0.32
Q9XSW7_PIG Phosphodiesterase 1.211e-18 0.30
XBP1_RAT Xbp1 X-box-binding protein 1 1.565e-14 0.32
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 6.917e-14 0.45
TF_HUMAN F3 Tissue factor 4.686e-09 0.34
Q49PX0_9POXV N1L N1L 9.971e-09 0.31
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.668e-08 0.31
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.058e-08 0.28
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.14e-07 0.35
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 3.991e-06 0.64

formononetin

IL2_HUMAN IL2 Interleukin-2 2.845e-44 1.00
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 6.806e-32 1.00
B4URF0_I33A0 Neuraminidase 0.0001828 1.00
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 5.811e-191 0.69
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.569e-45 0.67
BGLR_RAT Gusb Beta-glucuronidase 6.018e-43 0.42
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.673e-34 0.39
LYSC1_RAT Lyz1 Lysozyme C-1 1.527e-33 0.42
ESR2_HUMAN ESR2 Estrogen receptor beta 3.324e-30 0.50
HSC82_YEAST HSC82 ATP-dependent molecular chaperone HSC82 5.98e-30 0.29
ESR1_HUMAN ESR1 Estrogen receptor 1.275e-29 0.50
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.547e-28 0.35
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 3.829e-28 0.35
ESR2_RAT Esr2 Estrogen receptor beta 5.335e-27 0.33
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 6.237e-27 0.36
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 5.379e-25 0.31
VE6_HPV16 E6 Protein E6 5.379e-25 0.31
ESR1_RAT Esr1 Estrogen receptor 2.111e-24 0.33
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 2.549e-24 0.34
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 3.151e-24 0.67
CBS_HUMAN CBS Cystathionine beta-synthase 3.547e-24 0.35
Q9X688_CAUVI cckA Cell cycle histidine kinase CckA 4.377e-23 0.28
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 2.685e-22 0.34
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 9.057e-22 0.58
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.427e-21 0.50
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 2.318e-20 0.32
ESR1_MOUSE Esr1 Estrogen receptor 1.498e-19 0.33
ESR2_MOUSE Esr2 Estrogen receptor beta 1.498e-19 0.33
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.986e-19 0.33
PON1_HUMAN PON1 Serum paraoxonase/arylesterase 1 2.322e-19 0.31
MIF_HUMAN MIF Macrophage migration inhibitory factor 7.431e-19 0.46
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.96e-18 0.43
TRPM7_MOUSE Trpm7 Transient receptor potential cation channel subfamily M member 7 6.785e-18 0.28
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 1.786e-17 0.53
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.102e-17 0.38
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 5.404e-17 0.42
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 3.331e-16 0.31
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 3.331e-16 0.53
CALM1_HUMAN CALM1 Calmodulin-1 6.661e-16 0.31
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 1.887e-15 0.34
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.998e-15 0.50
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 3.331e-15 0.29
KLK7_HUMAN KLK7 Kallikrein-7 1.21e-14 0.69
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.799e-14 0.36
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 8.149e-14 0.39
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.346e-13 0.50
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 1.66e-13 0.36
IL5_MOUSE Il5 Interleukin-5 2.126e-13 0.40
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 2.157e-13 0.41
ACES_RAT Ache Acetylcholinesterase 3.159e-13 0.45
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 4.384e-13 0.38
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.128e-13 0.37
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.51e-12 0.34
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 2.757e-12 0.30
REST_BORBU resT Telomere resolvase ResT 3.217e-12 0.30
NANH_CLOPF nanH Sialidase 3.668e-12 0.37
EGLN1_RAT Egln1 Egl nine homolog 1 4.327e-12 0.34
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 6.14e-12 0.36
DPO1_THEAQ polA DNA polymerase I, thermostable 6.448e-12 0.58
BGLR_HUMAN GUSB Beta-glucuronidase 1.023e-11 0.33
FEN1_HUMAN FEN1 Flap endonuclease 1 1.327e-11 0.41
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 1.493e-11 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.765e-11 0.57
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 4.014e-11 0.39
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 1.082e-10 0.36
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.212e-10 0.31
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.663e-10 0.40
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.704e-10 0.37
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.741e-10 0.33
PERL_BOVIN LPO Lactoperoxidase 2.222e-10 0.33
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 3.371e-10 0.32
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.71e-10 0.53
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 5.293e-10 0.45
CP19A_HUMAN CYP19A1 Aromatase 6.395e-10 0.67
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 7.772e-10 0.50
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.459e-09 0.31
FACE2_HUMAN RCE1 CAAX prenyl protease 2 1.519e-09 0.33
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.553e-09 0.38
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.594e-09 0.37
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 5.775e-09 0.39
SQHC_ALIAD shc Squalene--hopene cyclase 6.075e-09 0.32
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 9.004e-09 0.43
A4_HUMAN APP Amyloid-beta precursor protein 1.432e-08 0.38
NOX4_HUMAN NOX4 NADPH oxidase 4 1.916e-08 0.39
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.143e-08 0.36
ALF_MYCTU fba Fructose-bisphosphate aldolase 2.609e-08 0.32
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 3.042e-08 0.67
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 3.152e-08 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.251e-08 0.43
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 4.239e-08 0.30
Q43570_TOBAC NtBBF1.1 Zn finger protein 4.403e-08 0.33
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 4.675e-08 0.28
SCAF_HHV11 UL26 Capsid scaffolding protein 5.7e-08 0.30
Q5J463_SALCH tem-1 Beta-lactamase 6.37e-08 0.32
SMO_MOUSE Smo Smoothened homolog 7.286e-08 0.40
TTHY_HUMAN TTR Transthyretin 1.614e-07 0.44
LUCI_PHOPY Luciferin 4-monooxygenase 1.731e-07 0.44
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 2.175e-07 0.50
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.522e-07 0.67
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 2.645e-07 0.28
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.756e-07 0.60
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 3.306e-07 0.50
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 3.884e-07 0.29
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 4.769e-07 0.32
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 4.858e-07 0.31
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 5.533e-07 0.28
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 6.036e-07 0.33
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 6.147e-07 0.47
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 8.937e-07 0.35
EST1_RABIT Liver carboxylesterase 1 1.033e-06 0.31
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 1.635e-06 0.43
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.723e-06 0.34
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 2.14e-06 0.40
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.456e-06 0.33
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.53e-06 0.35
CETP_RABIT CETP Cholesteryl ester transfer protein 2.931e-06 0.45
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 3.035e-06 0.38
TYRO_HUMAN TYR Tyrosinase 3.148e-06 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.21e-06 0.32
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 3.242e-06 0.33
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.439e-06 0.35
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.725e-06 0.36
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 7.367e-06 0.40
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 7.77e-06 0.28
CAH9_HUMAN CA9 Carbonic anhydrase 9 8.583e-06 0.39
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 8.755e-06 0.28

palmatine

ACES_ELEEL ache Acetylcholinesterase 5.362e-41 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.003082 1.00
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 2.033e-50 0.33
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 7.22e-48 0.58
CHLE_HORSE BCHE Cholinesterase 2.01e-31 0.75
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 6.387e-28 0.50
TBB5_HUMAN TUBB Tubulin beta chain 2.826e-24 0.30
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.887e-15 0.50
Q49PX0_9POXV N1L N1L 1.058e-09 0.35
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.521e-08 0.28
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.08e-07 0.35
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.228e-07 0.75
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.685e-07 0.32
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 9.524e-07 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.611e-06 0.30

baicalein

XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 3.15e-30 1.00
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 3.937e-30 1.00
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.735e-26 1.00
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 8.438e-15 1.00
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 2.276e-14 1.00
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.387e-14 1.00
Q7ZJM1_9HIV1 pol Integrase 5.082e-12 1.00
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 1.776e-10 1.00
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.53e-09 1.00
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.523e-07 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0006982 1.00
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.234e-136 0.71
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.097e-86 0.78
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.015e-62 0.45
TOP1_RAT Top1 DNA topoisomerase 1 9.005e-60 0.48
I3LTK9_PIG CEL Carboxylic ester hydrolase 7.9e-59 0.40
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 5.682e-54 0.69
VE6_HPV16 E6 Protein E6 4.512e-52 0.34
OPRD_PIG OPRD1 Delta-type opioid receptor 3.077e-50 0.40
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 5.933e-50 0.34
ACES_RAT Ache Acetylcholinesterase 3.789e-48 0.41
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 7.589e-47 0.71
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 2.521e-45 0.63
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 6.889e-43 0.34
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 9.763e-42 0.48
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 2.281e-40 0.32
DDL_HELPH ddl D-alanine--D-alanine ligase 2.281e-40 0.32
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.307e-39 0.78
FGR_RAT Fgr Tyrosine-protein kinase Fgr 4.474e-39 0.31
LYN_RAT Lyn Tyrosine-protein kinase Lyn 4.474e-39 0.31
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 2.255e-38 0.48
ARGI1_RAT Arg1 Arginase-1 2.696e-38 0.48
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 6.308e-38 0.54
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.634e-36 0.45
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 4.997e-36 0.48
NQO1_RAT Nqo1 NAD(P)H dehydrogenase [quinone] 1 9.362e-36 0.28
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 6.722e-35 0.43
BGLR_RAT Gusb Beta-glucuronidase 3.92e-33 0.54
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 5.697e-31 0.30
SYN1_BOVIN SYN1 Synapsin-1 1.372e-27 0.44
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 5.827e-26 0.32
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.258e-25 0.31
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 6.884e-24 0.76
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 1.572e-23 0.31
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.307e-23 0.44
COMT_HUMAN COMT Catechol O-methyltransferase 2.017e-22 0.32
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 3.756e-21 0.54
R1AB_SARS rep Replicase polyprotein 1ab 4.993e-21 0.40
PLGF_HUMAN PGF Placenta growth factor 8.931e-21 0.40
POLI_HUMAN POLI DNA polymerase iota 1.802e-19 0.31
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 6.208e-19 0.31
O96394_LEIAM Arginase 7.192e-19 0.34
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.026e-18 0.47
ACES_ELEEL ache Acetylcholinesterase 3.061e-18 0.38
PON1_HUMAN PON1 Serum paraoxonase/arylesterase 1 4.879e-18 0.29
DOPO_HUMAN DBH Dopamine beta-hydroxylase 3.302e-17 0.34
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 3.927e-17 0.31
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 2.22e-16 0.31
POLH_HUMAN POLH DNA polymerase eta 3.331e-16 0.31
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.11e-15 0.35
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.554e-15 0.42
P89582_9HIV2 pol Integrase 1.776e-15 0.34
NANH_CLOPF nanH Sialidase 3.22e-15 0.48
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 8.549e-15 0.45
CALM1_HUMAN CALM1 Calmodulin-1 1.388e-14 0.54
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.565e-14 0.48
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.732e-14 0.61
COMT_RAT Comt Catechol O-methyltransferase 2.931e-14 0.32
Q72874_9HIV1 pol Pol polyprotein 3.819e-14 0.47
DPO1_THEAQ polA DNA polymerase I, thermostable 6.672e-14 0.41
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 7.072e-14 0.54
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.391e-13 0.54
LYAM1_HUMAN SELL L-selectin 1.663e-13 0.30
CBS_HUMAN CBS Cystathionine beta-synthase 2.829e-13 0.36
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 5.338e-13 0.28
TLR1_MOUSE Tlr1 Toll-like receptor 1 8.059e-13 0.39
TLR2_MOUSE Tlr2 Toll-like receptor 2 8.059e-13 0.39
CSK21_RAT Csnk2a1 Casein kinase II subunit alpha 1.191e-12 0.31
CSK2B_RAT Csnk2b Casein kinase II subunit beta 1.191e-12 0.31
REST_BORBU resT Telomere resolvase ResT 2.334e-12 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.417e-12 0.40
LGUL_HUMAN GLO1 Lactoylglutathione lyase 5.679e-12 0.48
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 6.918e-12 0.43
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 7.469e-12 0.48
KSYK_RAT Syk Tyrosine-protein kinase SYK 1.659e-11 0.31
NOX4_HUMAN NOX4 NADPH oxidase 4 1.777e-11 0.54
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.181e-11 0.53
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 4.757e-11 0.30
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 5.639e-11 0.55
TERT_HUMAN TERT Telomerase reverse transcriptase 1.172e-10 0.41
TNNC1_HUMAN TNNC1 Troponin C, slow skeletal and cardiac muscles 1.794e-10 0.39
TNNI3_HUMAN TNNI3 Troponin I, cardiac muscle 1.794e-10 0.39
TNNT2_HUMAN TNNT2 Troponin T, cardiac muscle 1.794e-10 0.39
MDH_THETH mdh Malate dehydrogenase 3.547e-10 0.32
PERL_BOVIN LPO Lactoperoxidase 3.547e-10 0.32
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 4.15e-10 0.54
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 6.988e-10 0.31
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.285e-09 0.31
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.52e-09 0.32
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.76e-09 0.30
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 2.944e-09 0.31
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 3.745e-09 0.54
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 8.374e-09 0.43
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 1.287e-08 0.32
Q49PX0_9POXV N1L N1L 1.709e-08 0.30
DCOR_HUMAN ODC1 Ornithine decarboxylase 2.148e-08 0.31
GPR35_HUMAN GPR35 G-protein coupled receptor 35 2.315e-08 0.48
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 4.168e-08 0.30
Q5J463_SALCH tem-1 Beta-lactamase 4.188e-08 0.35
ANDR_HUMAN AR Androgen receptor 6.403e-08 0.69
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 6.665e-08 0.31
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 8.63e-08 0.29
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 1.079e-07 0.62
DPP4_PIG DPP4 Dipeptidyl peptidase 4 1.132e-07 0.56
DRD2_RAT Drd2 D(2) dopamine receptor 1.392e-07 0.40
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 1.491e-07 0.54
LYAM3_HUMAN SELP P-selectin 1.584e-07 0.30
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 1.788e-07 0.32
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 2.115e-07 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.137e-07 0.31
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 2.137e-07 0.36
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 2.265e-07 0.38
TTHY_HUMAN TTR Transthyretin 2.302e-07 0.54
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 4.268e-07 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 4.535e-07 0.40
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 4.905e-07 0.29
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.092e-07 0.34
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.054e-06 0.32
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.132e-06 0.44
CHLE_HORSE BCHE Cholinesterase 1.153e-06 0.35
IL2_HUMAN IL2 Interleukin-2 1.962e-06 0.34
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 2.231e-06 0.56
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 2.322e-06 0.35
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 2.357e-06 0.40
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.437e-06 0.30
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 2.65e-06 0.31
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.686e-06 0.32
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.168e-06 0.28
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 3.168e-06 0.28
DPOL_VACCW POL DNA polymerase 4.23e-06 0.30
OXDA_HUMAN DAO D-amino-acid oxidase 4.888e-06 0.33
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 5.091e-06 0.28
A4_HUMAN APP Amyloid-beta precursor protein 5.351e-06 0.48
SL9A1_HUMAN SLC9A1 Sodium/hydrogen exchanger 1 6.012e-06 0.35
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 6.116e-06 0.48

DFV

CP19A_HUMAN CYP19A1 Aromatase 3.22e-15 1.00
B4URF0_I33A0 Neuraminidase 1.559e-06 1.00
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 8.41e-73 0.54
G6PD_YEAST ZWF1 Glucose-6-phosphate 1-dehydrogenase 3.253e-63 0.32
PLGF_HUMAN PGF Placenta growth factor 2.309e-52 0.42
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 6.904e-46 0.32
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 8.881e-46 0.35
ESR2_HUMAN ESR2 Estrogen receptor beta 2.147e-42 0.52
FUT4_HUMAN FUT4 Alpha-(1,3)-fucosyltransferase 4 2.427e-38 0.30
Q8I2S7_PLAF7 3-oxoacyl-[acyl-carrier-protein] reductase 2.427e-38 0.30
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 3.89e-38 0.32
ESR1_HUMAN ESR1 Estrogen receptor 1.664e-35 0.52
6PGD_HUMAN PGD 6-phosphogluconate dehydrogenase, decarboxylating 5.629e-33 0.32
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 1.079e-28 0.35
LYSC1_RAT Lyz1 Lysozyme C-1 2.258e-25 0.31
SIAT6_HUMAN ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.132e-24 0.30
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.847e-23 0.29
VE6_HPV16 E6 Protein E6 2.847e-23 0.29
O96394_LEIAM Arginase 2.531e-21 0.38
BGLR_RAT Gusb Beta-glucuronidase 1.193e-19 0.31
SECA1_STAA8 secA1 Protein translocase subunit SecA 1 3.691e-19 0.30
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 4.11e-19 0.30
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.08e-18 0.33
FTSZ_ECOLI ftsZ Cell division protein FtsZ 5.368e-18 0.34
ESR1_RAT Esr1 Estrogen receptor 2.908e-17 0.41
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 3.867e-17 0.42
KLK2_HUMAN KLK2 Kallikrein-2 2.22e-16 0.41
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 5.551e-16 0.31
AOFA_MOUSE Maoa Amine oxidase [flavin-containing] A 3.331e-15 0.29
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 4.441e-15 0.29
ACES_RAT Ache Acetylcholinesterase 7.216e-15 0.73
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 6.672e-14 0.30
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.442e-13 0.64
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 3.959e-13 0.32
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 4.735e-13 0.32
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 5.131e-13 0.33
DPOLB_RAT Polb DNA polymerase beta 5.378e-13 0.34
PPO2_AGABI PPO2 Polyphenol oxidase 2 6.368e-13 0.55
CBS_HUMAN CBS Cystathionine beta-synthase 4.037e-12 0.33
TYRO_MOUSE Tyr Tyrosinase 4.251e-12 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 6.858e-11 0.56
MTSI_SPISQ sssIM CPG DNA methylase 1.076e-09 0.30
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 6e-09 0.35
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 6.447e-09 0.33
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 3.314e-08 0.35
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.031e-07 0.29
ERG1_RAT Sqle Squalene monooxygenase 1.05e-07 0.30
TYRO_HUMAN TYR Tyrosinase 9.277e-07 0.35
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 1.6e-06 0.35
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 2.484e-06 0.35
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 4.596e-06 0.29
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 5.189e-06 0.30
CAH3_HUMAN CA3 Carbonic anhydrase 3 6.976e-06 0.38

(2S)-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8,8-dimethyl-2,3-dihydropyrano[2,3-f]chromen-4-one

PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 9.062e-11 1.00
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.191e-94 0.61
TYRO_MOUSE Tyr Tyrosinase 1.138e-52 0.38
NANH_CLOPF nanH Sialidase 4.121e-42 0.52
NANH_VIBCH nanH Sialidase 7.348e-34 0.33
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 1.201e-31 0.31
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 8.421e-24 0.46
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.695e-19 0.46
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 4.226e-19 0.30
FTSZ_ECOLI ftsZ Cell division protein FtsZ 3.055e-17 0.33
TYRO_HUMAN TYR Tyrosinase 2.72e-14 0.39
KLK2_HUMAN KLK2 Kallikrein-2 3.049e-13 0.33
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 2.203e-12 0.46
PPO2_AGABI PPO2 Polyphenol oxidase 2 8.644e-12 0.54
CP19A_HUMAN CYP19A1 Aromatase 2.912e-10 0.61
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.426e-09 0.70
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 4.307e-09 0.43
DPOLL_HUMAN POLL DNA polymerase lambda 5.818e-09 0.32
B4URF0_I33A0 Neuraminidase 1.362e-08 0.70
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 8.101e-08 0.70
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 2.147e-06 0.31
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 3.824e-06 0.28

epiberberine

SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 0.0005651 1.00
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 0.0006262 1.00
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.604e-48 0.60
ACES_ELEEL ache Acetylcholinesterase 4.695e-41 0.70
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 7.214e-39 0.45
CHLE_HORSE BCHE Cholinesterase 6.746e-33 0.70
RGS17_HUMAN RGS17 Regulator of G-protein signaling 17 2.652e-24 0.39
XBP1_RAT Xbp1 X-box-binding protein 1 1.565e-14 0.32
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 6.917e-14 0.45
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.668e-08 0.31
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.804e-06 0.70

beta-sitosterol

THRB_HUMAN F2 Prothrombin 0.9968 1.00
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 7.597e-103 0.73
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.865e-83 0.68
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 2.131e-74 0.70
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 5.687e-68 0.36
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.897e-67 0.56
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.972e-66 0.53
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 7.968e-66 0.39
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.668e-61 0.48
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.954e-57 0.72
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 3.773e-56 0.70
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.189e-55 0.73
VDR_RAT Vdr Vitamin D3 receptor 2.627e-51 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.811e-45 0.56
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 9.387e-45 0.48
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 2.371e-42 0.37
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 4.226e-42 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 6.366e-40 0.33
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.586e-40 0.54
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 3.269e-39 0.49
VDR_PIG VDR Vitamin D3 receptor 4.754e-38 0.30
VTDB_HUMAN GC Vitamin D-binding protein 4.754e-38 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 3.987e-37 0.60
VDRA_DANRE vdra Vitamin D3 receptor A 4.291e-37 0.30
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 8.297e-37 0.29
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.283e-36 0.46
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.654e-34 0.54
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.303e-33 0.45
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.964e-30 0.38
VDR_HUMAN VDR Vitamin D3 receptor 2.132e-29 0.41
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.063e-28 0.38
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.532e-26 0.58
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 6.795e-26 0.32
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 9.144e-26 0.79
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.436e-24 0.36
VDR_CHICK VDR Vitamin D3 receptor 2.922e-23 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 4.462e-21 0.43
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.832e-20 0.54
VDR_BOVIN VDR Vitamin D3 receptor 4.921e-20 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 3.237e-19 0.41
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.344e-18 0.36
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.698e-18 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 1.11e-16 0.49
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.22e-16 0.54
ECR_DROME EcR Ecdysone receptor 2.22e-16 0.30
ANDR_HUMAN AR Androgen receptor 5.551e-16 0.49
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.661e-16 0.31
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.663e-15 0.51
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7.438e-15 0.44
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.176e-14 0.70
REST_BORBU resT Telomere resolvase ResT 2.798e-14 0.35
ABCBB_HUMAN ABCB11 Bile salt export pump 3.186e-14 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.619e-14 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 8.215e-13 0.53
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.559e-12 0.53
ESR1_HUMAN ESR1 Estrogen receptor 3.32e-12 0.49
ANDR_RAT Ar Androgen receptor 4.219e-12 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.066e-12 0.53
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.066e-12 0.53
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.462e-11 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.274e-11 0.38
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 5.969e-11 0.53
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 5.969e-11 0.53
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.149e-11 0.53
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.365e-10 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.376e-10 0.53
SHH_MOUSE Shh Sonic hedgehog protein 3.63e-10 0.60
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.601e-10 0.56
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.373e-10 0.53
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.349e-09 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.37e-09 0.30
CP19A_HUMAN CYP19A1 Aromatase 2.019e-09 0.53
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.225e-09 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.152e-09 0.29
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.722e-09 0.66
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.109e-09 0.53
GLI1_HUMAN GLI1 Zinc finger protein GLI1 9.718e-09 0.31
DPOLB_RAT Polb DNA polymerase beta 2.644e-08 0.41
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 8.146e-08 0.74
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.17e-08 0.32
ANDR_MOUSE Ar Androgen receptor 1.124e-07 0.32
Q690N0_BOVIN PGR Progesterone receptor 1.742e-07 0.32
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.895e-07 0.29
SHH_HUMAN SHH Sonic hedgehog protein 5.577e-07 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 5.849e-07 0.35
RORG_HUMAN RORC Nuclear receptor ROR-gamma 7.332e-07 0.79
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.611e-06 0.29
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 7.896e-06 0.48

sitosterol

THRB_HUMAN F2 Prothrombin 0.9968 1.00
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 7.597e-103 0.73
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.865e-83 0.68
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 2.131e-74 0.70
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 5.687e-68 0.36
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.897e-67 0.56
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.972e-66 0.53
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 7.968e-66 0.39
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.668e-61 0.48
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.954e-57 0.72
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 3.773e-56 0.70
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.189e-55 0.73
VDR_RAT Vdr Vitamin D3 receptor 2.627e-51 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.811e-45 0.56
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 9.387e-45 0.48
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 2.371e-42 0.37
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 4.226e-42 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 6.366e-40 0.33
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.586e-40 0.54
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 3.269e-39 0.49
VDR_PIG VDR Vitamin D3 receptor 4.754e-38 0.30
VTDB_HUMAN GC Vitamin D-binding protein 4.754e-38 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 3.987e-37 0.60
VDRA_DANRE vdra Vitamin D3 receptor A 4.291e-37 0.30
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 8.297e-37 0.29
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.283e-36 0.46
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.654e-34 0.54
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.303e-33 0.45
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.964e-30 0.38
VDR_HUMAN VDR Vitamin D3 receptor 2.132e-29 0.41
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.063e-28 0.38
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.532e-26 0.58
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 6.795e-26 0.32
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 9.144e-26 0.79
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.436e-24 0.36
VDR_CHICK VDR Vitamin D3 receptor 2.922e-23 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 4.462e-21 0.43
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.832e-20 0.54
VDR_BOVIN VDR Vitamin D3 receptor 4.921e-20 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 3.237e-19 0.41
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.344e-18 0.36
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.698e-18 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 1.11e-16 0.49
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.22e-16 0.54
ECR_DROME EcR Ecdysone receptor 2.22e-16 0.30
ANDR_HUMAN AR Androgen receptor 5.551e-16 0.49
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.661e-16 0.31
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.663e-15 0.51
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7.438e-15 0.44
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.176e-14 0.70
REST_BORBU resT Telomere resolvase ResT 2.798e-14 0.35
ABCBB_HUMAN ABCB11 Bile salt export pump 3.186e-14 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.619e-14 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 8.215e-13 0.53
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.559e-12 0.53
ESR1_HUMAN ESR1 Estrogen receptor 3.32e-12 0.49
ANDR_RAT Ar Androgen receptor 4.219e-12 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.066e-12 0.53
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.066e-12 0.53
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.462e-11 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.274e-11 0.38
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 5.969e-11 0.53
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 5.969e-11 0.53
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.149e-11 0.53
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.365e-10 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.376e-10 0.53
SHH_MOUSE Shh Sonic hedgehog protein 3.63e-10 0.60
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.601e-10 0.56
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.373e-10 0.53
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.349e-09 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.37e-09 0.30
CP19A_HUMAN CYP19A1 Aromatase 2.019e-09 0.53
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.225e-09 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.152e-09 0.29
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.722e-09 0.66
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.109e-09 0.53
GLI1_HUMAN GLI1 Zinc finger protein GLI1 9.718e-09 0.31
DPOLB_RAT Polb DNA polymerase beta 2.644e-08 0.41
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 8.146e-08 0.74
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.17e-08 0.32
ANDR_MOUSE Ar Androgen receptor 1.124e-07 0.32
Q690N0_BOVIN PGR Progesterone receptor 1.742e-07 0.32
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.895e-07 0.29
SHH_HUMAN SHH Sonic hedgehog protein 5.577e-07 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 5.849e-07 0.35
RORG_HUMAN RORC Nuclear receptor ROR-gamma 7.332e-07 0.79
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.611e-06 0.29
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 7.896e-06 0.48

Daidzein-4,7-diglucoside

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.993e-177 0.59
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 1.705e-152 0.90
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 1.519e-72 0.38
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.414e-62 0.42
IL2_HUMAN IL2 Interleukin-2 4.488e-61 0.90
FAS_CHICK FASN Fatty acid synthase 5.676e-58 0.46
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 2.013e-50 0.36
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 6.701e-50 0.40
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 2.299e-48 0.38
B4EH87_BURCJ Lectin 2.565e-47 0.59
GOB1_BRUMA Trehalose-phosphatase 3.453e-43 0.34
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 3.453e-43 0.34
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 5.569e-40 0.36
RASN_HUMAN NRAS GTPase NRas 7.528e-39 0.31
PDIA1_HUMAN P4HB Protein disulfide-isomerase 6.838e-35 0.48
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 9.701e-35 0.35
TOP1_MOUSE Top1 DNA topoisomerase 1 4.446e-32 0.29
O96394_LEIAM Arginase 4.015e-31 0.48
ADOK_MYCTO adoK Adenosine kinase 4.573e-31 0.34
TYRO_HUMAN TYR Tyrosinase 7.244e-31 0.47
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 2.221e-29 0.90
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.966e-27 0.90
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 2.859e-26 0.32
CD22_HUMAN CD22 B-cell receptor CD22 2.018e-23 0.29
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 7.819e-23 0.38
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 7.563e-20 0.32
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.733e-19 0.32
FGF1_HUMAN FGF1 Fibroblast growth factor 1 7.046e-18 0.31
IL5_MOUSE Il5 Interleukin-5 3.322e-17 0.69
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.11e-16 0.35
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.776e-14 0.31
GDE_RABIT AGL Glycogen debranching enzyme 9.504e-14 0.30
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 8.451e-13 0.30
LEG9_HUMAN LGALS9 Galectin-9 1.116e-12 0.31
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.129e-11 0.48
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.464e-11 0.35
CAH12_HUMAN CA12 Carbonic anhydrase 12 4.365e-11 0.59
LEG3_HUMAN LGALS3 Galectin-3 1.209e-10 0.31
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.238e-10 0.31
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 5.069e-10 0.39
KLK7_HUMAN KLK7 Kallikrein-7 6.946e-10 0.41
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.133e-09 0.39
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 2.947e-09 0.35
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.355e-09 0.59
CD22_MOUSE Cd22 B-cell receptor CD22 4.864e-09 0.28
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.512e-08 0.28
SQHC_ALIAD shc Squalene--hopene cyclase 1.574e-08 0.31
LYAG_RAT Gaa Lysosomal alpha-glucosidase 2.051e-08 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.447e-08 0.48
RASH_HUMAN HRAS GTPase HRas 3.753e-08 0.30
IL6_HUMAN IL6 Interleukin-6 6.918e-08 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 8.247e-08 0.44
TOP1_HUMAN TOP1 DNA topoisomerase 1 1.037e-07 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.381e-07 0.34
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.702e-07 0.43
CAH4_HUMAN CA4 Carbonic anhydrase 4 2.389e-07 0.48
ACES_RAT Ache Acetylcholinesterase 3.234e-07 0.34
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.357e-07 0.59
CDD_MOUSE Cda Cytidine deaminase 4.905e-07 0.29
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 5.351e-07 0.48
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.482e-06 0.44
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 3.584e-06 0.48
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 5.091e-06 0.28
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 5.596e-06 0.48
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 8.821e-06 0.29
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 9.682e-06 0.29
CETP_RABIT CETP Cholesteryl ester transfer protein 9.841e-06 0.41

3'-Methoxydaidzein

ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 2.099e-165 0.55
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 3.096e-89 0.35
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.5e-53 0.50
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.422e-47 0.30
BGLR_RAT Gusb Beta-glucuronidase 1.271e-43 0.42
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 3.834e-41 0.48
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.386e-39 0.42
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.265e-38 0.71
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 1.102e-37 0.30
DDL_HELPH ddl D-alanine--D-alanine ligase 1.102e-37 0.30
TOP1_RAT Top1 DNA topoisomerase 1 1.609e-35 0.28
IL2_HUMAN IL2 Interleukin-2 3.089e-35 0.71
LYSC1_RAT Lyz1 Lysozyme C-1 8.367e-34 0.42
DHPR_HUMAN QDPR Dihydropteridine reductase 1.55e-28 0.38
ESR2_HUMAN ESR2 Estrogen receptor beta 2.225e-27 0.52
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.266e-26 0.36
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.486e-25 0.31
VE6_HPV16 E6 Protein E6 1.486e-25 0.31
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 3.479e-25 0.34
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 8.146e-25 0.35
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.744e-24 0.54
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.962e-24 0.30
NANH_CLOPF nanH Sialidase 5.296e-24 0.51
ESR1_HUMAN ESR1 Estrogen receptor 2.596e-23 0.47
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 2.847e-23 0.29
ARGI1_RAT Arg1 Arginase-1 7.04e-23 0.28
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 8.429e-23 0.36
TAU_HUMAN MAPT Microtubule-associated protein tau 1.254e-22 0.38
LGUL_HUMAN GLO1 Lactoylglutathione lyase 6.294e-22 0.34
MTSI_SPISQ sssIM CPG DNA methylase 2.01e-21 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.137e-20 0.47
DHPR_RAT Qdpr Dihydropteridine reductase 2.074e-20 0.38
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 5.615e-20 0.39
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 7.707e-20 0.36
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.97e-18 0.38
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 2.123e-18 0.34
A4_HUMAN APP Amyloid-beta precursor protein 3.461e-17 0.38
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 4.27e-17 0.37
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.11e-16 0.31
IL5_MOUSE Il5 Interleukin-5 1.11e-16 0.34
O96394_LEIAM Arginase 1.11e-16 0.30
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.22e-16 0.38
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 4.441e-16 0.42
TTHY_HUMAN TTR Transthyretin 1.221e-15 0.44
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.443e-15 0.32
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 4.219e-15 0.47
NANH_VIBCH nanH Sialidase 7.105e-15 0.28
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 7.438e-15 0.28
Q43570_TOBAC NtBBF1.1 Zn finger protein 2.021e-14 0.31
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 2.243e-14 0.43
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.72e-14 0.48
NOX4_HUMAN NOX4 NADPH oxidase 4 4.874e-14 0.42
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 8.415e-14 0.34
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.311e-13 0.43
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 2.428e-13 0.33
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 4.797e-13 0.39
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 6.35e-13 0.50
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.825e-13 0.34
ACES_RAT Ache Acetylcholinesterase 1.671e-12 0.48
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.812e-12 0.39
CAH13_HUMAN CA13 Carbonic anhydrase 13 6.636e-12 0.36
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 8.416e-12 0.34
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 1.118e-11 0.48
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.437e-11 0.31
BGLR_HUMAN GUSB Beta-glucuronidase 1.738e-11 0.32
ESR2_RAT Esr2 Estrogen receptor beta 1.843e-11 0.34
Q5J463_SALCH tem-1 Beta-lactamase 1.904e-11 0.33
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 2.43e-11 0.30
CBS_HUMAN CBS Cystathionine beta-synthase 3.542e-11 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.959e-11 0.50
ESR1_MOUSE Esr1 Estrogen receptor 9.183e-11 0.34
ESR2_MOUSE Esr2 Estrogen receptor beta 9.183e-11 0.34
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 9.456e-11 0.47
ESR1_RAT Esr1 Estrogen receptor 2.196e-10 0.34
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.711e-10 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 6.955e-10 0.46
CAH13_MOUSE Ca13 Carbonic anhydrase 13 7.59e-10 0.32
CAN_CANAL NCE103 Carbonic anhydrase 9.003e-10 0.32
O96526_LEIMA CRK3 Cdc2-related kinase 1.012e-09 0.28
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.045e-09 0.28
MDH_THETH mdh Malate dehydrogenase 1.543e-09 0.30
PERL_BOVIN LPO Lactoperoxidase 1.543e-09 0.30
Q49PX0_9POXV N1L N1L 1.557e-09 0.34
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.833e-09 0.43
MIF_HUMAN MIF Macrophage migration inhibitory factor 2.003e-09 0.52
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 2.246e-09 0.40
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.766e-09 0.32
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 4.307e-09 0.46
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.702e-09 0.47
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 5.995e-09 0.30
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 6.115e-09 0.33
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 7.245e-09 0.35
CCNA2_HUMAN CCNA2 Cyclin-A2 8.582e-09 0.39
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 9.729e-09 0.47
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.347e-08 0.34
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.465e-08 0.31
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.467e-08 0.47
SMO_MOUSE Smo Smoothened homolog 1.52e-08 0.45
KLK7_HUMAN KLK7 Kallikrein-7 1.754e-08 0.61
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.948e-08 0.47
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.035e-08 0.50
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 2.257e-08 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.324e-08 0.35
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.545e-08 0.38
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.666e-08 0.32
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.929e-08 0.29
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 3.233e-08 0.37
HSP82_YEAST HSP82 ATP-dependent molecular chaperone HSP82 4.633e-08 0.30
FACE2_HUMAN RCE1 CAAX prenyl protease 2 5.976e-08 0.38
Q932Y6_PSEAI bla(tem-2) Beta-lactamase 7.511e-08 0.47
CAH6_HUMAN CA6 Carbonic anhydrase 6 8.677e-08 0.35
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.031e-07 0.29
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.179e-07 0.54
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.475e-07 0.50
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.489e-07 0.47
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.519e-07 0.34
PDIA1_HUMAN P4HB Protein disulfide-isomerase 3.637e-07 0.35
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 4.072e-07 0.33
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 4.56e-07 0.35
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.815e-07 0.30
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 5.124e-07 0.30
FOS_HUMAN FOS Proto-oncogene c-Fos 5.744e-07 0.34
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 6.934e-07 0.33
Q7ZJM1_9HIV1 pol Integrase 9.272e-07 0.47
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.14e-06 0.29
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.683e-06 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.563e-06 0.28
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.98e-06 0.31
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 4.865e-06 0.29
GLR_RAT Gcgr Glucagon receptor 6.069e-06 0.39
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 6.425e-06 0.30
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 6.773e-06 0.38
DPO1_THEAQ polA DNA polymerase I, thermostable 7.559e-06 0.43
CAH9_HUMAN CA9 Carbonic anhydrase 9 7.637e-06 0.36

Calycosin

ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 3.197e-165 0.55
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.468e-54 0.50
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.422e-47 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.261e-44 0.71
BGLR_RAT Gusb Beta-glucuronidase 1.271e-43 0.42
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 3.818e-38 0.38
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 1.102e-37 0.30
DDL_HELPH ddl D-alanine--D-alanine ligase 1.102e-37 0.30
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.52e-37 0.38
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 4.377e-37 0.34
IL2_HUMAN IL2 Interleukin-2 7.482e-37 0.71
TOP1_RAT Top1 DNA topoisomerase 1 1.609e-35 0.28
LYSC1_RAT Lyz1 Lysozyme C-1 8.367e-34 0.42
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 8.669e-26 0.37
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.486e-25 0.31
VE6_HPV16 E6 Protein E6 1.486e-25 0.31
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 3.479e-25 0.34
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.962e-24 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 5.325e-24 0.47
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 2.847e-23 0.29
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 6.02e-23 0.36
ARGI1_RAT Arg1 Arginase-1 7.04e-23 0.28
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 5.912e-22 0.54
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.049e-21 0.35
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 6.65e-21 0.47
ESR1_HUMAN ESR1 Estrogen receptor 2.835e-20 0.47
NANH_CLOPF nanH Sialidase 5.779e-19 0.41
IL5_MOUSE Il5 Interleukin-5 1.324e-17 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.92e-17 0.37
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.11e-16 0.31
O96394_LEIAM Arginase 1.11e-16 0.30
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 2.22e-16 0.32
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.331e-16 0.38
NANH_VIBCH nanH Sialidase 8.882e-16 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.887e-15 0.36
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 7.438e-15 0.28
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 2.243e-14 0.43
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.311e-13 0.43
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 2.428e-13 0.33
Q43570_TOBAC NtBBF1.1 Zn finger protein 2.566e-13 0.29
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.588e-13 0.38
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 6.35e-13 0.50
ACES_RAT Ache Acetylcholinesterase 1.828e-12 0.48
NOX4_HUMAN NOX4 NADPH oxidase 4 2.536e-12 0.42
Q5J463_SALCH tem-1 Beta-lactamase 5.893e-12 0.35
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 6.299e-12 0.36
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 6.321e-12 0.45
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 1.615e-11 0.45
TTHY_HUMAN TTR Transthyretin 1.64e-11 0.44
ESR2_RAT Esr2 Estrogen receptor beta 1.843e-11 0.34
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 2.43e-11 0.30
ESR1_MOUSE Esr1 Estrogen receptor 9.183e-11 0.34
ESR2_MOUSE Esr2 Estrogen receptor beta 9.183e-11 0.34
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 9.456e-11 0.47
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 1.115e-10 0.32
CBS_HUMAN CBS Cystathionine beta-synthase 1.522e-10 0.28
ESR1_RAT Esr1 Estrogen receptor 2.196e-10 0.34
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.368e-10 0.30
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.711e-10 0.32
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.661e-10 0.29
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 7.379e-10 0.42
MDH_THETH mdh Malate dehydrogenase 1.543e-09 0.30
PERL_BOVIN LPO Lactoperoxidase 1.543e-09 0.30
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.772e-09 0.29
MTSI_SPISQ sssIM CPG DNA methylase 2.184e-09 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 2.474e-09 0.35
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 4.765e-09 0.30
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 5.258e-09 0.46
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 5.995e-09 0.30
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 6.111e-09 0.47
PPO2_AGABI PPO2 Polyphenol oxidase 2 6.272e-09 0.33
BGLR_HUMAN GUSB Beta-glucuronidase 8.189e-09 0.40
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 9.546e-09 0.47
KLK7_HUMAN KLK7 Kallikrein-7 1.754e-08 0.61
DHPR_RAT Qdpr Dihydropteridine reductase 1.813e-08 0.28
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 2.257e-08 0.31
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.321e-08 0.47
SMO_MOUSE Smo Smoothened homolog 2.345e-08 0.43
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.929e-08 0.29
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.063e-08 0.42
A3KMY8_BOVIN GUSB Beta-glucuronidase 3.901e-08 0.40
CAH13_HUMAN CA13 Carbonic anhydrase 13 4.26e-08 0.37
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 4.302e-08 0.40
HSP82_YEAST HSP82 ATP-dependent molecular chaperone HSP82 4.633e-08 0.30
MIF_HUMAN MIF Macrophage migration inhibitory factor 4.758e-08 0.52
DHPR_HUMAN QDPR Dihydropteridine reductase 5.363e-08 0.28
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.79e-07 0.47
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 4.072e-07 0.33
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 5.04e-07 0.34
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 5.124e-07 0.30
Q7ZJM1_9HIV1 pol Integrase 6.333e-07 0.47
HCK_HUMAN HCK Tyrosine-protein kinase HCK 6.383e-07 0.35
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.02e-07 0.54
CCNA2_HUMAN CCNA2 Cyclin-A2 7.229e-07 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 8.856e-07 0.44
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.037e-06 0.34
Q932Y6_PSEAI bla(tem-2) Beta-lactamase 1.045e-06 0.47
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.14e-06 0.29
TAU_HUMAN MAPT Microtubule-associated protein tau 1.211e-06 0.33
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.214e-06 0.50
LGUL_HUMAN GLO1 Lactoylglutathione lyase 2.092e-06 0.30
R1AB_SARS rep Replicase polyprotein 1ab 2.426e-06 0.32
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.683e-06 0.30
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.568e-06 0.50
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 4.605e-06 0.34
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 6.425e-06 0.30
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 6.773e-06 0.38
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 6.791e-06 0.50
DPO1_THEAQ polA DNA polymerase I, thermostable 7.559e-06 0.43
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 7.986e-06 0.36
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 8.874e-06 0.33

Moupinamide

SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 2.345e-128 0.49
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.837e-72 0.38
A4_HUMAN APP Amyloid-beta precursor protein 7.368e-58 0.61
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 4.559e-57 0.35
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 8.863e-52 0.43
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 5.752e-51 0.35
MTSI_SPISQ sssIM CPG DNA methylase 3.05e-49 0.66
TAU_HUMAN MAPT Microtubule-associated protein tau 6.358e-47 0.57
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 2.566e-45 0.32
FOXO1_HUMAN FOXO1 Forkhead box protein O1 4.407e-45 0.36
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 3.103e-43 0.46
PACR_RAT Adcyap1r1 Pituitary adenylate cyclase-activating polypeptide type I receptor 2.281e-40 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.609e-40 0.48
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 2.638e-40 0.37
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.329e-37 0.42
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.254e-36 0.39
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 3.875e-36 0.29
SCMU_MYCTU Secreted chorismate mutase 6.705e-36 0.28
TYTR_CRIFA TPR Trypanothione reductase 7.62e-36 0.28
MMP2_RAT Mmp2 72 kDa type IV collagenase 1.097e-35 0.28
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.699e-35 0.41
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 3.403e-35 0.37
ACES_ELEEL ache Acetylcholinesterase 5.711e-34 0.60
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.57e-33 0.61
HDAC1_HUMAN HDAC1 Histone deacetylase 1 3.954e-32 0.67
LGUL_HUMAN GLO1 Lactoylglutathione lyase 6.986e-32 0.61
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 2.606e-31 0.61
SPRE_HUMAN SPR Sepiapterin reductase 8.924e-31 0.36
CHLE_HORSE BCHE Cholinesterase 1.303e-30 0.55
NANA_STREE nanA Sialidase A 1.679e-30 0.34
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.692e-30 0.37
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.74e-29 0.50
Q7ZJM1_9HIV1 pol Integrase 6.488e-29 0.57
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.083e-26 0.39
DYN1_HUMAN DNM1 Dynamin-1 3.775e-26 0.34
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.653e-26 0.66
CAH6_HUMAN CA6 Carbonic anhydrase 6 5.161e-26 0.67
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 8.157e-26 0.67
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.245e-26 0.42
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.765e-25 0.48
MYOC_HUMAN MYOC Myocilin 4.179e-25 0.31
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 7.302e-25 0.67
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.999e-25 0.40
STXA_SHIDY stxA Shiga toxin subunit A 9.547e-25 0.32
1433S_HUMAN SFN 14-3-3 protein sigma 1.342e-24 0.30
POLG_CXB3N Genome polyprotein 1.438e-24 0.34
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.411e-24 0.50
H9TVJ1_CHISP TyR1 3.169e-24 0.30
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.293e-24 0.61
CAH13_MOUSE Ca13 Carbonic anhydrase 13 8.934e-24 0.67
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.303e-23 0.48
CHLE_HUMAN BCHE Cholinesterase 1.406e-23 0.55
CYSP_PLAFA Trophozoite cysteine proteinase 1.511e-23 0.37
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.512e-23 0.39
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 1.662e-23 0.42
CAN_CANAL NCE103 Carbonic anhydrase 1.937e-23 0.42
CAH14_HUMAN CA14 Carbonic anhydrase 14 8.54e-23 0.67
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.004e-22 0.61
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.021e-22 0.50
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.158e-22 0.42
MMP1_HUMAN MMP1 Interstitial collagenase 2.338e-22 0.60
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 1.452e-21 0.35
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.604e-21 0.55
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 2.269e-21 0.43
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.748e-21 0.42
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.399e-21 0.67
HDAC6_HUMAN HDAC6 Histone deacetylase 6 7.28e-21 0.67
HDA11_HUMAN HDAC11 Histone deacetylase 11 9.672e-21 0.38
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 6.701e-20 0.30
HDAC9_HUMAN HDAC9 Histone deacetylase 9 1.256e-19 0.38
MMP2_HUMAN MMP2 72 kDa type IV collagenase 3.232e-19 0.60
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.325e-19 0.39
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 8.07e-19 0.30
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 8.175e-19 0.36
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 4.453e-18 0.30
TTHY_HUMAN TTR Transthyretin 5.412e-18 0.55
Q49PX0_9POXV N1L N1L 2.9e-17 0.32
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.116e-17 0.52
DHPR_HUMAN QDPR Dihydropteridine reductase 1.11e-16 0.31
HPSE_HUMAN HPSE Heparanase 1.11e-16 0.34
FOS_HUMAN FOS Proto-oncogene c-Fos 2.22e-16 0.61
PA_I000X PA Polymerase acidic protein 4.441e-16 0.31
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 7.772e-16 0.33
ACES_HUMAN ACHE Acetylcholinesterase 9.992e-16 0.55
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 9.992e-16 0.49
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 1.221e-15 0.30
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 1.221e-15 0.30
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 1.221e-15 0.30
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 1.221e-15 0.30
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 1.221e-15 0.30
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 1.221e-15 0.30
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 1.221e-15 0.30
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 1.221e-15 0.30
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 1.221e-15 0.30
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 1.221e-15 0.30
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 1.221e-15 0.30
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 1.221e-15 0.30
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 1.221e-15 0.30
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 1.221e-15 0.30
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 1.221e-15 0.30
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 1.221e-15 0.30
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 1.221e-15 0.30
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 1.221e-15 0.30
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 1.221e-15 0.30
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 1.221e-15 0.30
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 1.221e-15 0.30
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 1.221e-15 0.30
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 1.221e-15 0.30
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 1.221e-15 0.30
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 1.221e-15 0.30
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 1.221e-15 0.30
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 1.221e-15 0.30
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 1.221e-15 0.30
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 1.221e-15 0.30
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 1.221e-15 0.30
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 1.221e-15 0.30
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 1.221e-15 0.30
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 1.221e-15 0.30
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 1.221e-15 0.30
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 1.221e-15 0.30
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 1.221e-15 0.30
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 1.221e-15 0.30
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 1.221e-15 0.30
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 1.221e-15 0.30
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 1.221e-15 0.30
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1.221e-15 0.30
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.221e-15 0.30
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 1.221e-15 0.30
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 1.221e-15 0.30
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 1.221e-15 0.30
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 1.221e-15 0.30
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 1.221e-15 0.30
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 1.221e-15 0.30
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.554e-15 0.38
BACE1_HUMAN BACE1 Beta-secretase 1 1.665e-15 0.61
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.776e-15 0.64
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.998e-15 0.29
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.665e-15 0.38
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 5.329e-15 0.43
EGFR_MOUSE Egfr Epidermal growth factor receptor 5.773e-15 0.33
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 8.327e-15 0.61
BKRB2_CAVPO BDKRB2 B2 bradykinin receptor 1.044e-14 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.099e-14 0.39
JUN_HUMAN JUN Transcription factor AP-1 1.243e-14 0.52
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.421e-14 0.34
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 1.465e-14 0.35
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 1.676e-14 0.32
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 5.129e-14 0.36
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 5.851e-14 0.34
Q9XYC7_PLAFA HDAC1 Histone deacetylase 7.55e-14 0.32
HDAC5_HUMAN HDAC5 Histone deacetylase 5 7.772e-14 0.35
Q25270_LEIDO beta-tubulin Beta-tubulin 9.193e-14 0.35
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.352e-13 0.34
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 4.967e-13 0.28
ADCY1_BOVIN ADCY1 Adenylate cyclase type 1 7.169e-13 0.31
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 1.25e-12 0.44
ESR1_HUMAN ESR1 Estrogen receptor 1.872e-12 0.39
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.016e-12 0.61
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 2.048e-12 0.49
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.481e-12 0.67
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.534e-12 0.33
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 3.497e-12 0.30
ABCBB_RAT Abcb11 Bile salt export pump 4.33e-12 0.29
ACES_TETCF ache Acetylcholinesterase 5.566e-12 0.36
HDAC4_HUMAN HDAC4 Histone deacetylase 4 7.611e-12 0.35
HDAC7_HUMAN HDAC7 Histone deacetylase 7 7.72e-12 0.32
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.376e-11 0.67
MIF_HUMAN MIF Macrophage migration inhibitory factor 1.639e-11 0.37
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.908e-11 0.30
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.948e-11 0.41
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 2.13e-11 0.34
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.308e-11 0.61
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.334e-11 0.35
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.691e-11 0.53
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 4.793e-11 0.34
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 5.156e-11 0.66
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 6.815e-11 0.42
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 6.95e-11 0.61
EP300_HUMAN EP300 Histone acetyltransferase p300 9.339e-11 0.61
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.007e-10 0.61
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.336e-10 0.28
LAT_MYCTU lat Probable L-lysine-epsilon aminotransferase 1.396e-10 0.31
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.781e-10 0.44
TF65_HUMAN RELA Transcription factor p65 1.986e-10 0.40
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.56e-10 0.35
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.608e-10 0.46
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 2.683e-10 0.33
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.795e-10 0.32
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 3.238e-10 0.30
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.54e-10 0.61
CAH13_HUMAN CA13 Carbonic anhydrase 13 4.795e-10 0.61
AGAL_HUMAN GLA Alpha-galactosidase A 5.219e-10 0.31
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 8.811e-10 0.28
CAH15_MOUSE Ca15 Carbonic anhydrase 15 9.196e-10 0.61
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.951e-10 0.38
GLR_HUMAN GCGR Glucagon receptor 1.004e-09 0.42
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 1.012e-09 0.28
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 1.062e-09 0.34
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.133e-09 0.61
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.37e-09 0.30
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 1.487e-09 0.31
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.692e-09 0.30
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.725e-09 0.40
LYAG_RAT Gaa Lysosomal alpha-glucosidase 1.998e-09 0.36
B4URF0_I33A0 Neuraminidase 2.185e-09 0.34
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 2.441e-09 0.44
DHPR_RAT Qdpr Dihydropteridine reductase 2.795e-09 0.31
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 3.26e-09 0.30
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 3.446e-09 0.33
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 3.759e-09 0.35
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 4.311e-09 0.38
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 5.781e-09 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 7.417e-09 0.29
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 8.019e-09 0.61
MET_HUMAN MET Hepatocyte growth factor receptor 8.48e-09 0.64
GLR_RAT Gcgr Glucagon receptor 9.988e-09 0.31
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.215e-08 0.41
NR1H4_HUMAN NR1H4 Bile acid receptor 1.535e-08 0.36
CALM1_HUMAN CALM1 Calmodulin-1 2.128e-08 0.30
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 2.295e-08 0.34
PERM_HUMAN MPO Myeloperoxidase 3.199e-08 0.39
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 4.633e-08 0.30
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 5.282e-08 0.53
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.174e-08 0.29
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 7.127e-08 0.29
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 7.559e-08 0.42
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.258e-07 0.33
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 1.291e-07 0.28
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.682e-07 0.38
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.706e-07 0.51
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.315e-07 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 2.38e-07 0.30
BKRB2_HUMAN BDKRB2 B2 bradykinin receptor 2.483e-07 0.31
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.612e-07 0.35
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 2.624e-07 0.43
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.836e-07 0.33
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 3.349e-07 0.61
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 3.903e-07 0.30
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.098e-07 0.30
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 5.164e-07 0.42
CNR2_HUMAN CNR2 Cannabinoid receptor 2 5.489e-07 0.71
ADCY1_HUMAN ADCY1 Adenylate cyclase type 1 5.7e-07 0.31
HDAC1_MOUSE Hdac1 Histone deacetylase 1 6.122e-07 0.39
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 6.436e-07 0.47
O49150_SOLTU Lipoxygenase 7.49e-07 0.34
HSF1_MOUSE Hsf1 Heat shock factor protein 1 7.759e-07 0.44
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 8.426e-07 0.42
TLR4_MOUSE Tlr4 Toll-like receptor 4 8.627e-07 0.61
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 9.132e-07 0.37
HDAC3_HUMAN HDAC3 Histone deacetylase 3 9.277e-07 0.38
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 9.501e-07 0.31
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.012e-06 0.42
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.012e-06 0.37
MIP_LEGPN mip Outer membrane protein MIP 1.023e-06 0.28
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 1.075e-06 0.37
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.182e-06 0.29
NRAM_I77AB Neuraminidase 1.287e-06 0.61
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 1.313e-06 0.37
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 1.337e-06 0.39
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.444e-06 0.40
Q932Y6_PSEAI bla(tem-2) Beta-lactamase 1.477e-06 0.66
LYAM2_HUMAN SELE E-selectin 1.516e-06 0.32
Q9ZTP8_MAIZE hd1b Histone deacetylase 1.676e-06 0.31
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.807e-06 0.39
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 2.207e-06 0.36
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.409e-06 0.29
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.532e-06 0.55
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 2.703e-06 0.33
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 2.703e-06 0.33
PTGES_HUMAN PTGES Prostaglandin E synthase 2.728e-06 0.61
C3SLB7_ECOLX glmU Bifunctional protein GlmU 2.845e-06 0.30
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 2.974e-06 0.32
LSHR_HUMAN LHCGR Lutropin-choriogonadotropic hormone receptor 3.64e-06 0.29
TYTR_TRYCR TPR Trypanothione reductase 3.976e-06 0.47
TLR9_HUMAN TLR9 Toll-like receptor 9 4.228e-06 0.66
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 4.899e-06 0.34
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 5.709e-06 0.55
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.956e-06 0.33
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 7.364e-06 0.41
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 7.652e-06 0.28
LUCI_PHOPY Luciferin 4-monooxygenase 7.661e-06 0.34
TF_HUMAN F3 Tissue factor 7.816e-06 0.61
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 9.518e-06 0.33

kaempferol

VE6_HPV16 E6 Protein E6 1.656e-118 0.75
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 7.496e-99 0.78
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 1.375e-97 0.78
DDL_HELPH ddl D-alanine--D-alanine ligase 1.375e-97 0.78
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 2.025e-93 0.75
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.407e-81 0.78
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.364e-79 0.78
O96394_LEIAM Arginase 1.438e-79 0.78
BGLR_RAT Gusb Beta-glucuronidase 1.975e-63 0.57
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.462e-62 0.78
TOP1_RAT Top1 DNA topoisomerase 1 9.005e-60 0.48
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 9.919e-60 0.44
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.099e-59 0.75
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 5.492e-59 0.75
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 6.135e-58 0.81
FAS_CHICK FASN Fatty acid synthase 4.562e-54 0.43
OPRD_PIG OPRD1 Delta-type opioid receptor 1.947e-53 0.43
CBS_HUMAN CBS Cystathionine beta-synthase 9.017e-51 0.45
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.491e-50 0.81
ESR1_MOUSE Esr1 Estrogen receptor 7.987e-47 0.34
ESR2_MOUSE Esr2 Estrogen receptor beta 7.987e-47 0.34
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 5.513e-45 0.30
PDIA1_HUMAN P4HB Protein disulfide-isomerase 6.101e-41 0.52
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.632e-39 0.78
ARGI1_RAT Arg1 Arginase-1 2.696e-38 0.48
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 3.17e-38 0.75
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 4.6e-38 0.81
LYSC1_RAT Lyz1 Lysozyme C-1 2.422e-37 0.47
SYN1_BOVIN SYN1 Synapsin-1 8.499e-34 0.55
R1AB_SARS rep Replicase polyprotein 1ab 2.327e-32 0.78
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 4.522e-28 0.45
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 6.232e-27 0.78
NANH_CLOPF nanH Sialidase 9.989e-27 0.78
ESR2_HUMAN ESR2 Estrogen receptor beta 2.751e-25 0.57
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 7.143e-25 0.31
MDH_THETH mdh Malate dehydrogenase 8.712e-24 0.78
PERL_BOVIN LPO Lactoperoxidase 8.712e-24 0.78
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.704e-23 0.45
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 3.005e-22 0.78
PLGF_HUMAN PGF Placenta growth factor 4.553e-22 0.43
NOX4_HUMAN NOX4 NADPH oxidase 4 1.895e-21 0.78
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 2.329e-21 0.34
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.132e-20 0.78
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 6.256e-20 0.78
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.72e-19 0.31
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 9.51e-19 0.78
PON1_HUMAN PON1 Serum paraoxonase/arylesterase 1 4.879e-18 0.29
ESR2_RAT Esr2 Estrogen receptor beta 9.645e-18 0.34
ESR1_HUMAN ESR1 Estrogen receptor 1.205e-17 0.57
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.517e-17 0.44
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 3.205e-17 0.78
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 4.608e-17 0.81
Q7ZJM1_9HIV1 pol Integrase 3.331e-16 0.75
ESR1_RAT Esr1 Estrogen receptor 4.441e-16 0.34
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 6.661e-16 0.48
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 8.882e-16 0.51
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 8.882e-16 0.78
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.331e-15 0.78
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.254e-14 0.78
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 3.031e-14 0.44
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.259e-13 0.78
CAH4_HUMAN CA4 Carbonic anhydrase 4 5.188e-13 0.81
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 9.615e-13 0.47
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.4e-12 0.39
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.729e-12 0.81
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 3.704e-12 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.361e-12 0.75
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 8.019e-12 0.78
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.323e-11 0.78
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.746e-11 0.68
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 3.464e-11 0.43
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 4.071e-11 0.75
IL2_HUMAN IL2 Interleukin-2 8.063e-11 0.30
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.441e-10 0.33
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 1.574e-10 0.78
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.882e-10 0.81
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 2.158e-10 0.41
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 5.138e-10 0.43
GPR35_HUMAN GPR35 G-protein coupled receptor 35 8.369e-10 0.78
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 8.542e-10 0.78
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.079e-09 0.57
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.397e-09 0.43
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.424e-09 0.78
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 4.692e-09 0.78
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 7.87e-09 0.37
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 9.095e-09 0.78
DPO1_THEAQ polA DNA polymerase I, thermostable 1.833e-08 0.35
Q43570_TOBAC NtBBF1.1 Zn finger protein 2.917e-08 0.34
5NTD_RAT Nt5e 5'-nucleotidase 3.124e-08 0.78
CALM1_HUMAN CALM1 Calmodulin-1 3.985e-08 0.29
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 4.803e-08 0.57
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 6.488e-08 0.33
TTHY_HUMAN TTR Transthyretin 1.271e-07 0.57
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.436e-07 0.57
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.756e-07 0.43
PERM_HUMAN MPO Myeloperoxidase 1.932e-07 0.78
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.337e-07 0.78
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 4.123e-07 0.78
GBB1_HUMAN GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 4.707e-07 0.30
GBG2_HUMAN GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 4.707e-07 0.30
CAH3_HUMAN CA3 Carbonic anhydrase 3 6.477e-07 0.78
IL5_MOUSE Il5 Interleukin-5 8.366e-07 0.36
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.07e-06 0.45
TAU_HUMAN MAPT Microtubule-associated protein tau 1.459e-06 0.75
B4URF0_I33A0 Neuraminidase 1.47e-06 0.78
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.943e-06 0.78
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.155e-06 0.56
TERT_HUMAN TERT Telomerase reverse transcriptase 3.593e-06 0.36
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 3.841e-06 0.38
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 4.158e-06 0.81
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 5.119e-06 0.78
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.779e-06 0.81
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 6.116e-06 0.48
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 7.158e-06 0.57
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 7.568e-06 0.75
DPP4_PIG DPP4 Dipeptidyl peptidase 4 8.017e-06 0.40

wogonin

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 8.274e-112 0.67
I3LTK9_PIG CEL Carboxylic ester hydrolase 3.341e-95 0.45
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 5.824e-84 0.62
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.299e-54 0.74
OPRD_PIG OPRD1 Delta-type opioid receptor 6.114e-52 0.41
ACES_RAT Ache Acetylcholinesterase 2.695e-48 0.40
TOP1_RAT Top1 DNA topoisomerase 1 7.497e-47 0.37
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 9.172e-47 0.31
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 9.466e-46 0.62
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.015e-44 0.64
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 2.682e-42 0.53
A6H249_FLAPJ pop Prolyl oligopeptidase family protein 3.56e-37 0.29
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 8.317e-35 0.49
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.101e-31 0.54
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.147e-30 0.38
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.147e-30 0.38
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 1.849e-30 0.38
ARGI1_RAT Arg1 Arginase-1 4.406e-30 0.37
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 2.482e-27 0.50
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.771e-26 0.60
BGLR_RAT Gusb Beta-glucuronidase 6.439e-26 0.42
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 9.592e-25 0.62
CCNO_HUMAN CCNO Cyclin-O 9.719e-24 0.29
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 2.457e-22 0.36
PLGF_HUMAN PGF Placenta growth factor 1.833e-21 0.41
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.135e-20 0.37
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 1.167e-20 0.37
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.745e-20 0.29
AMY1A_HUMAN AMY1A Alpha-amylase 1 8.872e-20 0.38
PERL_BOVIN LPO Lactoperoxidase 8.96e-20 0.35
ACES_ELEEL ache Acetylcholinesterase 1.561e-19 0.40
CDC2H_PLAF7 CRK2 Cell division control protein 2 homolog 3.055e-19 0.37
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 3.592e-19 0.48
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 1.708e-18 0.30
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.721e-18 0.49
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.11e-16 0.37
CBS_HUMAN CBS Cystathionine beta-synthase 1.11e-16 0.47
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 1.11e-16 0.31
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.11e-16 0.37
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 1.11e-16 0.37
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.887e-15 0.50
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 3.886e-15 0.29
REST_BORBU resT Telomere resolvase ResT 5.662e-15 0.37
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 8.549e-15 0.38
Q72874_9HIV1 pol Pol polyprotein 1.865e-14 0.44
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.463e-13 0.33
TERT_HUMAN TERT Telomerase reverse transcriptase 2.595e-13 0.43
CCNT1_HUMAN CCNT1 Cyclin-T1 2.97e-13 0.52
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 5.008e-13 0.38
P89582_9HIV2 pol Integrase 5.125e-13 0.28
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 5.466e-13 0.55
CALM1_HUMAN CALM1 Calmodulin-1 2.846e-12 0.45
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 4.245e-12 0.50
DPO1_THEAQ polA DNA polymerase I, thermostable 4.459e-12 0.33
NANH_CLOPF nanH Sialidase 4.466e-12 0.37
AHR_HUMAN AHR Aryl hydrocarbon receptor 8.33e-12 0.45
CCNA2_HUMAN CCNA2 Cyclin-A2 9.283e-12 0.52
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 1.274e-11 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.761e-11 0.37
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.691e-11 0.45
AVR2A_HUMAN ACVR2A Activin receptor type-2A 6.813e-11 0.37
CCNK_HUMAN CCNK Cyclin-K 6.878e-11 0.29
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 7.581e-11 0.42
DCOR_HUMAN ODC1 Ornithine decarboxylase 4.059e-10 0.38
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 4.56e-10 0.55
NANA_STREE nanA Sialidase A 4.884e-10 0.29
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 8.495e-10 0.35
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 9.605e-10 0.37
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 9.605e-10 0.37
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.317e-09 0.52
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.37e-09 0.33
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 2.793e-09 0.37
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 2.793e-09 0.37
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.793e-09 0.37
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 2.793e-09 0.37
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 4.354e-09 0.38
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 7.154e-09 0.37
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 7.418e-09 0.46
NOX4_HUMAN NOX4 NADPH oxidase 4 7.605e-09 0.42
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 7.65e-09 0.29
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 1.811e-08 0.42
CHLE_HORSE BCHE Cholinesterase 3.04e-08 0.39
ESR2_HUMAN ESR2 Estrogen receptor beta 3.446e-08 0.46
CAH13_HUMAN CA13 Carbonic anhydrase 13 3.45e-08 0.38
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 3.495e-08 0.37
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 4.055e-08 0.55
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.238e-08 0.37
DOPO_HUMAN DBH Dopamine beta-hydroxylase 4.633e-08 0.30
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 4.657e-08 0.48
AVR2B_HUMAN ACVR2B Activin receptor type-2B 6.878e-08 0.37
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 6.878e-08 0.37
COMT_HUMAN COMT Catechol O-methyltransferase 1.07e-07 0.29
Q5J463_SALCH tem-1 Beta-lactamase 1.08e-07 0.31
EGLN1_RAT Egln1 Egl nine homolog 1 1.194e-07 0.29
BGLR_HUMAN GUSB Beta-glucuronidase 1.203e-07 0.31
CATL2_HUMAN CTSV Cathepsin L2 1.295e-07 0.41
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.426e-07 0.38
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.523e-07 0.31
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.609e-07 0.50
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 1.991e-07 0.46
DPP4_PIG DPP4 Dipeptidyl peptidase 4 2.22e-07 0.53
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 2.229e-07 0.37
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 2.28e-07 0.50
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 2.737e-07 0.41
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 3.731e-07 0.37
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 3.731e-07 0.37
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 3.884e-07 0.29
DRD2_RAT Drd2 D(2) dopamine receptor 4.161e-07 0.36
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 4.402e-07 0.37
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 5.996e-07 0.37
A3KMY8_BOVIN GUSB Beta-glucuronidase 7.329e-07 0.31
ANDR_HUMAN AR Androgen receptor 7.345e-07 0.53
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 7.516e-07 0.33
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 9.301e-07 0.37
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.14e-06 0.29
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.244e-06 0.50
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.275e-06 0.38
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.391e-06 0.53
ACVR1_HUMAN ACVR1 Activin receptor type-1 1.647e-06 0.37
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.968e-06 0.54
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 2.044e-06 0.37
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 2.103e-06 0.38
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 2.756e-06 0.31
CCNH_HUMAN CCNH Cyclin-H 2.765e-06 0.38
DMPK_HUMAN DMPK Myotonin-protein kinase 2.915e-06 0.37
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 3.277e-06 0.37
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 3.781e-06 0.33
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 4.064e-06 0.37
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 4.183e-06 0.54
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.671e-06 0.51
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 4.824e-06 0.31
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 5.121e-06 0.42
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 5.553e-06 0.37
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 5.553e-06 0.37
SL9A1_HUMAN SLC9A1 Sodium/hydrogen exchanger 1 6.274e-06 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.289e-06 0.50
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 6.581e-06 0.30
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 6.854e-06 0.51
COMT_RAT Comt Catechol O-methyltransferase 6.888e-06 0.29
TTHY_HUMAN TTR Transthyretin 7.409e-06 0.42
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 7.451e-06 0.37
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 7.451e-06 0.37
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 7.451e-06 0.37
AA1R_RAT Adora1 Adenosine receptor A1 7.486e-06 0.53
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 9.058e-06 0.42
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 9.104e-06 0.34
TLR1_MOUSE Tlr1 Toll-like receptor 1 9.511e-06 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 9.511e-06 0.29
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 9.833e-06 0.37
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 9.833e-06 0.37
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 9.833e-06 0.37
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 9.833e-06 0.37

Supraene

A7L861_PIG SQLE Squalene epoxidase 7.654e-102 0.74
LSS_RAT Lss Lanosterol synthase 1.413e-87 0.47
ERG1_HUMAN SQLE Squalene monooxygenase 6.108e-80 0.74
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 2.827e-77 0.55
AOX_TRYBB AOX Alternative oxidase, mitochondrial 1.142e-66 0.41
FDFT_YEAST ERG9 Squalene synthase 2.742e-57 0.46
FDFT_RAT Fdft1 Squalene synthase 2.14e-56 0.62
ERG7_CANAL ERG7 Lanosterol synthase 4.815e-52 0.41
STE14_YEAST STE14 Protein-S-isoprenylcysteine O-methyltransferase 1.081e-42 0.53
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.61e-39 0.41
ERG1_RAT Sqle Squalene monooxygenase 1.151e-35 0.81
FNTA_YEAST RAM2 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 3.019e-31 0.31
ERG7_PNECA ERG7 Lanosterol synthase 5.283e-27 0.33
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 3.214e-24 0.33
LSS_HUMAN LSS Lanosterol synthase 3.45e-23 0.47
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 7.972e-21 0.41
PA2_APIME Phospholipase A2 2.382e-20 0.33
AOFA_MOUSE Maoa Amine oxidase [flavin-containing] A 7.888e-18 0.34
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 4.441e-16 0.41
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 6.291e-12 0.59
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 3.447e-11 0.59
BT3A1_HUMAN BTN3A1 Butyrophilin subfamily 3 member A1 3.542e-11 0.30
ICMT_HUMAN ICMT Protein-S-isoprenylcysteine O-methyltransferase 1.179e-09 0.57
ERG7_YEAST ERG7 Lanosterol synthase 8.357e-09 0.33
FNTB_BOVIN FNTB Protein farnesyltransferase subunit beta 2.576e-08 0.53
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 5.351e-07 0.32
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 5.526e-07 0.53
FDFT_HUMAN FDFT1 Squalene synthase 3.202e-06 0.55

5,7,4'-trihydroxy-6-methoxyflavanone

T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 1.845e-100 0.80
G6PD_YEAST ZWF1 Glucose-6-phosphate 1-dehydrogenase 1.213e-58 0.30
TYRO_MOUSE Tyr Tyrosinase 4.251e-43 0.42
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 4.474e-40 0.31
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.084e-35 0.32
FUT4_HUMAN FUT4 Alpha-(1,3)-fucosyltransferase 4 1.377e-35 0.28
Q8I2S7_PLAF7 3-oxoacyl-[acyl-carrier-protein] reductase 1.377e-35 0.28
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 8.208e-35 0.30
O96394_LEIAM Arginase 7.42e-34 0.31
DCOR_HUMAN ODC1 Ornithine decarboxylase 2.62e-33 0.36
PLGF_HUMAN PGF Placenta growth factor 7.421e-32 0.34
6PGD_HUMAN PGD 6-phosphogluconate dehydrogenase, decarboxylating 1.29e-30 0.30
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 5.843e-29 0.30
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 3.637e-25 0.31
SIAT6_HUMAN ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6.377e-23 0.28
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 7.474e-19 0.36
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 9.056e-18 0.28
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 9.84e-18 0.34
FTSZ_ECOLI ftsZ Cell division protein FtsZ 1.072e-17 0.34
KLK2_HUMAN KLK2 Kallikrein-2 1.11e-16 0.42
ACES_RAT Ache Acetylcholinesterase 2.22e-16 0.64
CBS_HUMAN CBS Cystathionine beta-synthase 4.108e-15 0.41
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.144e-14 0.39
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.376e-14 0.62
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.719e-13 0.34
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 6.108e-13 0.28
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.792e-12 0.46
DPOLB_RAT Polb DNA polymerase beta 7.133e-12 0.32
CP19A_HUMAN CYP19A1 Aromatase 9.613e-12 0.57
ITF2_HUMAN TCF4 Transcription factor 4 4.543e-11 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 6.323e-11 0.54
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.332e-10 0.34
ESR1_HUMAN ESR1 Estrogen receptor 3.281e-10 0.61
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 3.757e-10 0.30
MTSI_SPISQ sssIM CPG DNA methylase 4.864e-09 0.28
IL6_HUMAN IL6 Interleukin-6 4.372e-08 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 5.142e-08 0.46
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 6.548e-08 0.31
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 2.921e-07 0.31
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.887e-07 0.59
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 4.59e-07 0.31
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 7.516e-07 0.33
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.118e-06 0.54
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.791e-06 0.38
TYRO_HUMAN TYR Tyrosinase 2.359e-06 0.30
B4URF0_I33A0 Neuraminidase 5.071e-06 0.52
R1AB_SARS rep Replicase polyprotein 1ab 7.752e-06 0.57
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 8.709e-06 0.31

naringenin

T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 7.08e-96 0.74
PLGF_HUMAN PGF Placenta growth factor 5.895e-72 0.45
G6PD_YEAST ZWF1 Glucose-6-phosphate 1-dehydrogenase 3.724e-70 0.36
Q8IDJ8_PLAF7 Lysine--tRNA ligase 1.126e-61 0.31
O96394_LEIAM Arginase 7.987e-43 0.42
FUT4_HUMAN FUT4 Alpha-(1,3)-fucosyltransferase 4 9.523e-43 0.34
Q8I2S7_PLAF7 3-oxoacyl-[acyl-carrier-protein] reductase 9.523e-43 0.34
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 9.441e-42 0.32
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.001e-41 0.36
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.373e-41 0.36
BGLR_RAT Gusb Beta-glucuronidase 1.518e-38 0.33
OPRD_PIG OPRD1 Delta-type opioid receptor 2.707e-37 0.30
TYRO_MOUSE Tyr Tyrosinase 3.056e-37 0.37
6PGD_HUMAN PGD 6-phosphogluconate dehydrogenase, decarboxylating 1.469e-36 0.36
SIAT6_HUMAN ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.79e-27 0.34
CBS_HUMAN CBS Cystathionine beta-synthase 8.375e-27 0.47
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 3.343e-26 0.32
LYSC1_RAT Lyz1 Lysozyme C-1 2.158e-24 0.30
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 2.196e-23 0.45
KLK2_HUMAN KLK2 Kallikrein-2 9.059e-23 0.57
DCOR_HUMAN ODC1 Ornithine decarboxylase 4.004e-22 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 2.212e-21 0.63
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 2.917e-21 0.34
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 9.561e-20 0.43
FTSZ_ECOLI ftsZ Cell division protein FtsZ 1.245e-19 0.38
SECA1_STAA8 secA1 Protein translocase subunit SecA 1 2.139e-18 0.29
VKOR1_BOVIN VKORC1 Vitamin K epoxide reductase complex subunit 1 4.879e-18 0.29
ESR1_HUMAN ESR1 Estrogen receptor 4.378e-17 0.63
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.22e-16 0.82
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 4.441e-16 0.31
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 1.887e-15 0.34
ACES_RAT Ache Acetylcholinesterase 2.998e-15 0.61
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.998e-14 0.36
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.431e-14 0.31
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 5.287e-13 0.34
DPOLB_RAT Polb DNA polymerase beta 1.221e-12 0.33
CP19A_HUMAN CYP19A1 Aromatase 1.529e-12 0.82
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.561e-12 0.38
ERG1_RAT Sqle Squalene monooxygenase 3.152e-12 0.34
REST_BORBU resT Telomere resolvase ResT 6.736e-12 0.29
MTSI_SPISQ sssIM CPG DNA methylase 9.638e-11 0.34
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.35e-10 0.72
ESR1_RAT Esr1 Estrogen receptor 2.351e-10 0.36
R1AB_SARS rep Replicase polyprotein 1ab 1.098e-09 0.69
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.242e-09 0.45
CAH3_HUMAN CA3 Carbonic anhydrase 3 5.265e-09 0.42
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 3.244e-08 0.32
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 1.541e-07 0.32
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.745e-07 0.30
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 4.561e-07 0.50
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.706e-07 0.61
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.392e-06 0.42
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 5.293e-06 0.32
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 5.445e-06 0.53
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 7.896e-06 0.29

Lupiwighteone

NANH_CLOPF nanH Sialidase 1.371e-90 0.75
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 1.302e-69 0.48
NANH_VIBCH nanH Sialidase 4.115e-47 0.33
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 3.651e-44 0.41
BGLR_RAT Gusb Beta-glucuronidase 1.239e-42 0.40
OPRD_PIG OPRD1 Delta-type opioid receptor 3.56e-37 0.29
PLCG1_RAT Plcg1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 7.142e-37 0.29
TYRO_MOUSE Tyr Tyrosinase 6.034e-36 0.32
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.059e-32 0.53
LYSC1_RAT Lyz1 Lysozyme C-1 6.125e-32 0.40
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 6.303e-30 0.43
AOX_TRYBB AOX Alternative oxidase, mitochondrial 6.841e-29 0.35
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 3.672e-23 0.50
IL2_HUMAN IL2 Interleukin-2 8.237e-23 0.38
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.049e-20 0.45
PLGF_HUMAN PGF Placenta growth factor 1.665e-15 0.29
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 1.665e-15 0.43
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 6.328e-15 0.41
IL5_MOUSE Il5 Interleukin-5 2.555e-13 0.38
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 7.413e-13 0.75
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.051e-12 0.31
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 3.431e-12 0.30
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 8.108e-12 0.35
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.431e-11 0.42
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 5.278e-11 0.42
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 5.412e-11 0.35
FEN1_HUMAN FEN1 Flap endonuclease 1 1.441e-10 0.30
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 4.372e-10 0.30
TYRO_HUMAN TYR Tyrosinase 4.639e-10 0.36
ACES_RAT Ache Acetylcholinesterase 8.441e-10 0.40
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 2.902e-09 0.60
XPO1_HUMAN XPO1 Exportin-1 6.978e-09 0.32
CATL2_HUMAN CTSV Cathepsin L2 1.433e-08 0.45
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 1.91e-07 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.126e-07 0.42
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.017e-07 0.50
TF65_HUMAN RELA Transcription factor p65 5.769e-07 0.42
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 7.711e-07 0.33
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.928e-07 0.31
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.028e-06 0.42
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 1.334e-06 0.41
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 2.147e-06 0.33
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 9.085e-06 0.50

5,7,4'-Trihydroxy-8-methoxyflavone

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 7.546e-90 0.53
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 5.033e-76 0.58
OPRD_PIG OPRD1 Delta-type opioid receptor 7.341e-65 0.52
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 6.871e-60 0.79
TOP1_RAT Top1 DNA topoisomerase 1 9.185e-54 0.43
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.997e-51 0.54
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 2.43e-41 0.43
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.68e-40 0.43
ACES_RAT Ache Acetylcholinesterase 1.222e-39 0.46
I3LTK9_PIG CEL Carboxylic ester hydrolase 2.868e-37 0.34
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 2.973e-37 0.49
A6H249_FLAPJ pop Prolyl oligopeptidase family protein 3.56e-37 0.29
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 8.858e-37 0.29
DDL_HELPH ddl D-alanine--D-alanine ligase 8.858e-37 0.29
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.026e-35 0.43
ARGI1_RAT Arg1 Arginase-1 1.78e-34 0.43
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 6.918e-34 0.42
BGLR_RAT Gusb Beta-glucuronidase 1.147e-33 0.55
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 4.294e-32 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 8.271e-30 0.55
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 9.002e-30 0.55
CBS_HUMAN CBS Cystathionine beta-synthase 4.582e-29 0.52
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.52e-28 0.35
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 1.52e-28 0.35
PLGF_HUMAN PGF Placenta growth factor 1.101e-26 0.52
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.526e-26 0.38
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 8.088e-26 0.64
AMY1A_HUMAN AMY1A Alpha-amylase 1 9.23e-26 0.50
ESR2_HUMAN ESR2 Estrogen receptor beta 1.513e-24 0.58
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 1.114e-23 0.29
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 4.633e-23 0.28
VE6_HPV16 E6 Protein E6 4.633e-23 0.28
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 7.04e-23 0.28
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 9.978e-22 0.59
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.573e-21 0.54
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 6.654e-21 0.33
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 3.95e-19 0.33
PERL_BOVIN LPO Lactoperoxidase 6.456e-19 0.33
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 5.07e-18 0.37
ESR1_HUMAN ESR1 Estrogen receptor 9.757e-18 0.55
ESR1_MOUSE Esr1 Estrogen receptor 1.254e-17 0.29
ESR2_MOUSE Esr2 Estrogen receptor beta 1.254e-17 0.29
CDC2H_PLAF7 CRK2 Cell division control protein 2 homolog 3.332e-17 0.33
DPO1_THEAQ polA DNA polymerase I, thermostable 4.749e-17 0.38
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 4.752e-17 0.42
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.22e-16 0.55
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 5.551e-16 0.43
NANH_CLOPF nanH Sialidase 1.554e-15 0.43
TERT_HUMAN TERT Telomerase reverse transcriptase 3.775e-15 0.53
REST_BORBU resT Telomere resolvase ResT 5.662e-15 0.37
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 5.662e-15 0.33
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 6.106e-15 0.28
NOX4_HUMAN NOX4 NADPH oxidase 4 8.449e-14 0.55
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.343e-13 0.29
ACES_ELEEL ache Acetylcholinesterase 2.59e-13 0.48
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 2.904e-13 0.34
P89582_9HIV2 pol Integrase 5.125e-13 0.28
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.875e-12 0.50
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.997e-12 0.29
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 5.253e-12 0.55
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 6.155e-12 0.38
IL2_HUMAN IL2 Interleukin-2 9.161e-12 0.33
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 1.998e-11 0.34
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 7.306e-11 0.29
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 9.42e-11 0.39
CALM1_HUMAN CALM1 Calmodulin-1 9.42e-11 0.39
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 1.116e-10 0.29
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 1.131e-10 0.44
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 2.017e-10 0.33
CCNT1_HUMAN CCNT1 Cyclin-T1 3.491e-10 0.52
NANA_STREE nanA Sialidase A 4.884e-10 0.29
AVR2A_HUMAN ACVR2A Activin receptor type-2A 8.973e-10 0.33
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.067e-09 0.36
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.105e-09 0.55
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.423e-09 0.43
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.752e-09 0.36
MDH_THETH mdh Malate dehydrogenase 2.533e-09 0.29
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.599e-09 0.38
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 2.853e-09 0.55
DPP4_PIG DPP4 Dipeptidyl peptidase 4 3.758e-09 0.67
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 5.929e-09 0.52
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 9.469e-09 0.33
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 9.469e-09 0.33
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 9.523e-09 0.29
O96394_LEIAM Arginase 9.523e-09 0.29
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 1.176e-08 0.55
CCNA2_HUMAN CCNA2 Cyclin-A2 1.338e-08 0.52
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 2.45e-08 0.33
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 2.45e-08 0.33
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.45e-08 0.33
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 2.45e-08 0.33
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 3.007e-08 0.68
R1AB_SARS rep Replicase polyprotein 1ab 4.445e-08 0.52
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 5.664e-08 0.33
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.95e-08 0.54
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 6.995e-08 0.29
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 7.044e-08 0.33
CAH7_HUMAN CA7 Carbonic anhydrase 7 7.616e-08 0.43
LGUL_HUMAN GLO1 Lactoylglutathione lyase 8.328e-08 0.43
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 1.148e-07 0.55
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.3e-07 0.38
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 1.394e-07 0.33
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.548e-07 0.67
A4_HUMAN APP Amyloid-beta precursor protein 1.569e-07 0.46
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.089e-07 0.33
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 2.282e-07 0.54
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 2.328e-07 0.33
AVR2B_HUMAN ACVR2B Activin receptor type-2B 4.255e-07 0.33
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 4.255e-07 0.33
TTHY_HUMAN TTR Transthyretin 4.26e-07 0.55
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.38e-07 0.35
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 5.001e-07 0.34
AHR_HUMAN AHR Aryl hydrocarbon receptor 5.41e-07 0.33
ESR2_RAT Esr2 Estrogen receptor beta 6.623e-07 0.29
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 7.308e-07 0.29
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 7.667e-07 0.55
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 1.214e-06 0.33
Q7ZJM1_9HIV1 pol Integrase 1.296e-06 0.55
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.303e-06 0.30
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.858e-06 0.28
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.921e-06 0.33
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.921e-06 0.33
ANDR_HUMAN AR Androgen receptor 2.135e-06 0.55
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 2.208e-06 0.68
ESR1_RAT Esr1 Estrogen receptor 2.826e-06 0.29
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 2.933e-06 0.33
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 3.627e-06 0.49
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 3.677e-06 0.29
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 4.338e-06 0.33
CHLE_HORSE BCHE Cholinesterase 6.683e-06 0.40
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 7.008e-06 0.38
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 8.755e-06 0.33
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 9.7e-06 0.35

5,2'-Dihydroxy-6,7,8-trimethoxyflavone

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 5.733e-87 0.52
I3LTK9_PIG CEL Carboxylic ester hydrolase 9.116e-67 0.38
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.434e-63 0.59
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.377e-49 0.67
OPRD_PIG OPRD1 Delta-type opioid receptor 1.122e-42 0.34
TOP1_RAT Top1 DNA topoisomerase 1 9.952e-40 0.31
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.088e-39 0.50
FGR_RAT Fgr Tyrosine-protein kinase Fgr 1.225e-37 0.30
LYN_RAT Lyn Tyrosine-protein kinase Lyn 1.225e-37 0.30
A6H249_FLAPJ pop Prolyl oligopeptidase family protein 1.775e-36 0.29
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 5.271e-29 0.31
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 5.876e-28 0.35
ACES_RAT Ache Acetylcholinesterase 2.179e-26 0.37
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 3.656e-26 0.32
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 5.085e-26 0.32
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 5.085e-26 0.32
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 9.952e-26 0.42
ARGI1_RAT Arg1 Arginase-1 1.486e-25 0.31
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 4.834e-23 0.30
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.42e-22 0.51
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 1.475e-20 0.33
BGLR_RAT Gusb Beta-glucuronidase 1.617e-20 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.739e-19 0.47
CDC2H_PLAF7 CRK2 Cell division control protein 2 homolog 5.806e-19 0.36
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 7.916e-19 0.31
POLI_HUMAN POLI DNA polymerase iota 9.052e-19 0.30
PLGF_HUMAN PGF Placenta growth factor 1.015e-17 0.34
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.872e-17 0.43
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.11e-16 0.32
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 2.22e-16 0.36
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.11e-15 0.39
POLH_HUMAN POLH DNA polymerase eta 1.11e-15 0.30
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.998e-15 0.31
P89582_9HIV2 pol Integrase 6.55e-15 0.33
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 6.772e-15 0.29
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1.388e-14 0.38
CBS_HUMAN CBS Cystathionine beta-synthase 2.598e-14 0.39
CSK21_RAT Csnk2a1 Casein kinase II subunit alpha 3.325e-12 0.30
CSK2B_RAT Csnk2b Casein kinase II subunit beta 3.325e-12 0.30
REST_BORBU resT Telomere resolvase ResT 5.06e-12 0.29
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 6.983e-12 0.37
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.018e-11 0.37
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 1.859e-11 0.36
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.811e-11 0.41
TLR1_MOUSE Tlr1 Toll-like receptor 1 3.326e-11 0.31
TLR2_MOUSE Tlr2 Toll-like receptor 2 3.326e-11 0.31
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 3.839e-11 0.30
KSYK_RAT Syk Tyrosine-protein kinase SYK 4.196e-11 0.30
AVR2A_HUMAN ACVR2A Activin receptor type-2A 9.696e-11 0.36
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.103e-10 0.36
CATL2_HUMAN CTSV Cathepsin L2 1.414e-10 0.40
DCOR_HUMAN ODC1 Ornithine decarboxylase 6.093e-10 0.38
AHR_HUMAN AHR Aryl hydrocarbon receptor 8.133e-10 0.43
TAT_HV1H2 tat Protein Tat 8.811e-10 0.28
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.314e-09 0.36
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.314e-09 0.36
TERT_HUMAN TERT Telomerase reverse transcriptase 1.335e-09 0.40
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.104e-09 0.37
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 3.085e-09 0.36
CALM1_HUMAN CALM1 Calmodulin-1 3.465e-09 0.33
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 3.76e-09 0.36
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 3.76e-09 0.36
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 3.76e-09 0.36
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 3.76e-09 0.36
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 6.138e-09 0.30
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 6.712e-09 0.36
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 9.496e-09 0.36
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.357e-08 0.37
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.947e-08 0.36
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 4.531e-08 0.36
O40947_HHV8 ORF 73 5.132e-08 0.34
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 5.25e-08 0.39
AVR2B_HUMAN ACVR2B Activin receptor type-2B 8.826e-08 0.36
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 8.826e-08 0.36
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.031e-07 0.29
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.113e-07 0.31
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.238e-07 0.30
IL6_HUMAN IL6 Interleukin-6 1.849e-07 0.29
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 2.811e-07 0.36
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 3.349e-07 0.36
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 4.231e-07 0.30
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 4.669e-07 0.36
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 4.669e-07 0.36
TNNC1_HUMAN TNNC1 Troponin C, slow skeletal and cardiac muscles 4.813e-07 0.33
TNNI3_HUMAN TNNI3 Troponin I, cardiac muscle 4.813e-07 0.33
TNNT2_HUMAN TNNT2 Troponin T, cardiac muscle 4.813e-07 0.33
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.982e-07 0.37
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 5.258e-07 0.43
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.479e-07 0.37
GBB1_HUMAN GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 5.972e-07 0.30
GBG2_HUMAN GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 5.972e-07 0.30
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 6.984e-07 0.33
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 7.451e-07 0.36
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 8.343e-07 0.38
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 8.43e-07 0.34
TTHY_HUMAN TTR Transthyretin 9.454e-07 0.33
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 1.148e-06 0.36
DPP4_PIG DPP4 Dipeptidyl peptidase 4 1.163e-06 0.46
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.482e-06 0.29
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.513e-06 0.56
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.664e-06 0.32
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.837e-06 0.31
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 2.077e-06 0.36
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.134e-06 0.30
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 2.494e-06 0.36
DMPK_HUMAN DMPK Myotonin-protein kinase 3.538e-06 0.36
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 4.005e-06 0.55
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 4.272e-06 0.34
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 4.296e-06 0.30
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 4.909e-06 0.36
NOX4_HUMAN NOX4 NADPH oxidase 4 6.15e-06 0.33
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 6.677e-06 0.36
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 6.677e-06 0.36
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 8.858e-06 0.37
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 8.92e-06 0.36
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8.92e-06 0.36
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 8.92e-06 0.36
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 9.936e-06 0.36

dihydrooroxylin A

T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 3.018e-84 0.66
TYRO_MOUSE Tyr Tyrosinase 4.251e-43 0.42
FUT4_HUMAN FUT4 Alpha-(1,3)-fucosyltransferase 4 1.377e-35 0.28
Q8I2S7_PLAF7 3-oxoacyl-[acyl-carrier-protein] reductase 1.377e-35 0.28
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 2.546e-34 0.39
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 2.748e-33 0.28
DCOR_HUMAN ODC1 Ornithine decarboxylase 4.99e-32 0.34
NAC1_HUMAN SLC8A1 Sodium/calcium exchanger 1 1.197e-30 0.30
G6PD_YEAST ZWF1 Glucose-6-phosphate 1-dehydrogenase 7.066e-29 0.28
E1BKU0_BOVIN ADORA2A Adenosine receptor A2 5.245e-24 0.30
SIAT6_HUMAN ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6.377e-23 0.28
FTSZ_ECOLI ftsZ Cell division protein FtsZ 7.249e-22 0.42
VKOR1_BOVIN VKORC1 Vitamin K epoxide reductase complex subunit 1 1.048e-19 0.31
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 5.861e-18 0.35
ACES_RAT Ache Acetylcholinesterase 5.918e-18 0.54
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 9.056e-18 0.28
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 2.715e-17 0.28
O96394_LEIAM Arginase 1.11e-16 0.29
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 4.441e-16 0.31
1A15_ARATH ACS5 1-aminocyclopropane-1-carboxylate synthase 5 9.992e-16 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.554e-15 0.62
6PGD_HUMAN PGD 6-phosphogluconate dehydrogenase, decarboxylating 2.998e-15 0.28
CP19A_HUMAN CYP19A1 Aromatase 7.883e-15 0.62
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.144e-14 0.39
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.921e-14 0.28
KLK2_HUMAN KLK2 Kallikrein-2 2.598e-14 0.35
DRD1_CARAU D(1) dopamine receptor 3.575e-14 0.36
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 3.612e-13 0.32
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 6.108e-13 0.28
CBS_HUMAN CBS Cystathionine beta-synthase 1.043e-12 0.34
LX15B_HUMAN ALOX15B Arachidonate 15-lipoxygenase B 1.196e-11 0.28
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 1.286e-11 0.34
ITF2_HUMAN TCF4 Transcription factor 4 4.543e-11 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 6.538e-10 0.29
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 7.541e-10 0.29
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 9.098e-10 0.54
MTSI_SPISQ sssIM CPG DNA methylase 4.864e-09 0.28
IL6_HUMAN IL6 Interleukin-6 1.414e-08 0.34
Q49PX0_9POXV N1L N1L 3.985e-08 0.29
DRD1_RAT Drd1 D(1A) dopamine receptor 5.297e-08 0.36
BGLR_HUMAN GUSB Beta-glucuronidase 6.166e-08 0.31
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 8.015e-08 0.34
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 1.031e-07 0.29
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.087e-07 0.37
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 2.925e-07 0.28
A3KMY8_BOVIN GUSB Beta-glucuronidase 4.041e-07 0.31
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 7.12e-07 0.69
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.13e-06 0.41
CATL2_HUMAN CTSV Cathepsin L2 1.316e-06 0.30
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.611e-06 0.30
BXA1_CLOBH botA Botulinum neurotoxin type A 2.07e-06 0.28
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 3.562e-06 0.28
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 8.404e-06 0.28
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 9.213e-06 0.32

5,7,2',6'-Tetrahydroxyflavone

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 4.459e-80 0.41
TOP1_RAT Top1 DNA topoisomerase 1 5.64e-80 0.64
BGLR_RAT Gusb Beta-glucuronidase 6.43e-69 0.72
OPRD_PIG OPRD1 Delta-type opioid receptor 7.174e-69 0.55
VE6_HPV16 E6 Protein E6 1.329e-67 0.44
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 9.214e-65 0.64
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 3.411e-57 0.50
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 2.089e-55 0.64
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 7.566e-52 0.41
DDL_HELPH ddl D-alanine--D-alanine ligase 7.566e-52 0.41
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 2.325e-51 0.41
ARGI1_RAT Arg1 Arginase-1 3.87e-51 0.64
O96394_LEIAM Arginase 6.573e-48 0.41
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.366e-43 0.41
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.632e-42 0.64
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.773e-41 0.72
FAS_CHICK FASN Fatty acid synthase 4.265e-38 0.30
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.615e-35 0.44
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.094e-35 0.72
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 6.719e-34 0.72
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.939e-33 0.41
LYSC1_RAT Lyz1 Lysozyme C-1 6e-33 0.41
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 3.098e-32 0.40
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 3.098e-32 0.40
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 3.838e-30 0.45
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 1.127e-29 0.37
PLGF_HUMAN PGF Placenta growth factor 2.639e-28 0.55
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 1.79e-27 0.34
CBS_HUMAN CBS Cystathionine beta-synthase 9.695e-27 0.46
AMY1A_HUMAN AMY1A Alpha-amylase 1 9.23e-26 0.50
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 4.754e-23 0.58
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 7.309e-23 0.44
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 7.766e-22 0.35
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.173e-18 0.72
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 3.661e-18 0.68
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.177e-17 0.72
NOX4_HUMAN NOX4 NADPH oxidase 4 1.197e-17 0.72
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.385e-17 0.64
PDIA1_HUMAN P4HB Protein disulfide-isomerase 3.331e-16 0.33
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 1.11e-15 0.30
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.332e-15 0.33
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.554e-15 0.41
LGUL_HUMAN GLO1 Lactoylglutathione lyase 3.22e-15 0.64
AHR_HUMAN AHR Aryl hydrocarbon receptor 6.772e-15 0.43
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 7.438e-15 0.47
ACES_RAT Ache Acetylcholinesterase 1.099e-14 0.36
P89582_9HIV2 pol Integrase 1.421e-14 0.32
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.954e-14 0.47
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.587e-14 0.41
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 5.437e-13 0.72
MDH_THETH mdh Malate dehydrogenase 6.6e-13 0.41
PERL_BOVIN LPO Lactoperoxidase 6.6e-13 0.41
NANH_CLOPF nanH Sialidase 1.411e-12 0.64
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.991e-12 0.72
ESR2_HUMAN ESR2 Estrogen receptor beta 2.01e-12 0.72
R1AB_SARS rep Replicase polyprotein 1ab 3.912e-12 0.55
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 4.298e-12 0.41
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 5.097e-12 0.41
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 7.627e-12 0.72
REST_BORBU resT Telomere resolvase ResT 1.23e-11 0.28
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.598e-11 0.72
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 2.079e-11 0.44
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 3.608e-11 0.72
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 5.158e-11 0.47
TLR1_MOUSE Tlr1 Toll-like receptor 1 6.542e-11 0.30
TLR2_MOUSE Tlr2 Toll-like receptor 2 6.542e-11 0.30
DPO1_THEAQ polA DNA polymerase I, thermostable 6.599e-11 0.45
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.352e-10 0.40
CALM1_HUMAN CALM1 Calmodulin-1 1.702e-10 0.38
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.049e-10 0.30
Q7ZJM1_9HIV1 pol Integrase 2.498e-10 0.72
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 4.256e-10 0.64
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 4.839e-10 0.72
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 6.251e-10 0.72
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 7.04e-10 0.47
TTHY_HUMAN TTR Transthyretin 1.04e-09 0.72
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.715e-09 0.36
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.805e-09 0.55
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 1.982e-09 0.41
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.937e-08 0.41
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 4.525e-08 0.50
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 5.369e-08 0.32
Q5J463_SALCH tem-1 Beta-lactamase 6.164e-08 0.33
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 6.224e-08 0.40
CAH4_HUMAN CA4 Carbonic anhydrase 4 8.846e-08 0.64
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 9.416e-08 0.64
Q43570_TOBAC NtBBF1.1 Zn finger protein 1.003e-07 0.32
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.046e-07 0.42
ESR1_HUMAN ESR1 Estrogen receptor 2.735e-07 0.72
ANDR_HUMAN AR Androgen receptor 2.972e-07 0.72
TYRO_HUMAN TYR Tyrosinase 3.489e-07 0.68
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.82e-07 0.47
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 5.095e-07 0.31
IL2_HUMAN IL2 Interleukin-2 6.624e-07 0.37
GPR35_HUMAN GPR35 G-protein coupled receptor 35 6.991e-07 0.64
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 9.539e-07 0.72
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 9.786e-07 0.36
PERM_HUMAN MPO Myeloperoxidase 1.011e-06 0.72
ULA1_HUMAN NAE1 NEDD8-activating enzyme E1 regulatory subunit 1.485e-06 0.52
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 1.501e-06 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.06e-06 0.59
DPP4_PIG DPP4 Dipeptidyl peptidase 4 2.562e-06 0.44
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 2.73e-06 0.64
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.845e-06 0.64
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.129e-06 0.33
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.134e-06 0.64
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 3.346e-06 0.29
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.906e-06 0.64

5,8,2'-Trihydroxy-7-methoxyflavone

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.751e-75 0.43
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.178e-66 0.66
OPRD_PIG OPRD1 Delta-type opioid receptor 2.199e-45 0.36
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.039e-42 0.67
TOP1_RAT Top1 DNA topoisomerase 1 9.952e-40 0.31
FGR_RAT Fgr Tyrosine-protein kinase Fgr 1.225e-37 0.30
LYN_RAT Lyn Tyrosine-protein kinase Lyn 1.225e-37 0.30
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.219e-33 0.39
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.219e-33 0.39
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 4.61e-32 0.42
ACES_RAT Ache Acetylcholinesterase 7.385e-32 0.40
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 3.968e-31 0.30
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 1.275e-29 0.37
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 1.71e-28 0.37
I3LTK9_PIG CEL Carboxylic ester hydrolase 1.943e-27 0.33
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 4.502e-26 0.32
ARGI1_RAT Arg1 Arginase-1 1.486e-25 0.31
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.12e-24 0.45
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.212e-24 0.30
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 4.212e-24 0.30
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 7.117e-24 0.31
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 2.07e-23 0.38
CDC2H_PLAF7 CRK2 Cell division control protein 2 homolog 4.358e-21 0.41
BGLR_RAT Gusb Beta-glucuronidase 1.617e-20 0.33
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 3.829e-20 0.34
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.446e-19 0.53
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 5.736e-19 0.43
PLGF_HUMAN PGF Placenta growth factor 8.175e-19 0.36
POLI_HUMAN POLI DNA polymerase iota 9.052e-19 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.388e-18 0.45
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 2.51e-18 0.41
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.11e-16 0.32
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 3.331e-16 0.42
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.11e-15 0.39
POLH_HUMAN POLH DNA polymerase eta 1.11e-15 0.30
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.998e-15 0.31
CBS_HUMAN CBS Cystathionine beta-synthase 4.441e-15 0.41
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 6.772e-15 0.29
NANH_CLOPF nanH Sialidase 2.598e-14 0.34
P89582_9HIV2 pol Integrase 7.883e-14 0.30
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 9.837e-14 0.37
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 1.044e-12 0.41
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.624e-12 0.31
CSK21_RAT Csnk2a1 Casein kinase II subunit alpha 3.325e-12 0.30
CSK2B_RAT Csnk2b Casein kinase II subunit beta 3.325e-12 0.30
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 4.298e-12 0.41
REST_BORBU resT Telomere resolvase ResT 5.06e-12 0.29
AVR2A_HUMAN ACVR2A Activin receptor type-2A 6.597e-12 0.41
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.018e-11 0.37
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.783e-11 0.32
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.811e-11 0.41
KSYK_RAT Syk Tyrosine-protein kinase SYK 4.196e-11 0.30
CAH13_HUMAN CA13 Carbonic anhydrase 13 4.869e-11 0.43
FIBB_HUMAN FGB Fibrinogen beta chain 5.659e-11 0.29
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.209e-10 0.41
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.209e-10 0.41
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.309e-10 0.28
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.901e-10 0.43
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 2.211e-10 0.41
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 3.907e-10 0.41
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 3.907e-10 0.41
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 3.907e-10 0.41
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 3.907e-10 0.41
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 5.576e-10 0.41
DCOR_HUMAN ODC1 Ornithine decarboxylase 6.093e-10 0.38
NANA_STREE nanA Sialidase A 7.541e-10 0.29
CCNT1_HUMAN CCNT1 Cyclin-T1 1.015e-09 0.42
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 1.098e-09 0.41
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.699e-09 0.39
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 6.138e-09 0.30
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 6.276e-09 0.41
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 8.719e-09 0.29
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.147e-08 0.41
CCNA2_HUMAN CCNA2 Cyclin-A2 1.157e-08 0.42
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 1.298e-08 0.42
AVR2B_HUMAN ACVR2B Activin receptor type-2B 1.32e-08 0.41
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.32e-08 0.41
TERT_HUMAN TERT Telomerase reverse transcriptase 1.326e-08 0.45
Q49PX0_9POXV N1L N1L 1.528e-08 0.30
ACES_ELEEL ache Acetylcholinesterase 1.819e-08 0.33
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 2.064e-08 0.37
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.383e-08 0.43
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 2.903e-08 0.30
O40947_HHV8 ORF 73 3.842e-08 0.37
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 3.938e-08 0.35
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 4.803e-08 0.41
LUCI_RENRE Coelenterazine h 2-monooxygenase 5.058e-08 0.28
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 8.456e-08 0.41
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 8.456e-08 0.41
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.031e-07 0.29
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.238e-07 0.30
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.424e-07 0.41
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.306e-07 0.41
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 3.321e-07 0.29
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.23e-07 0.37
Q43570_TOBAC NtBBF1.1 Zn finger protein 4.268e-07 0.29
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.474e-07 0.41
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 5.681e-07 0.42
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 6.497e-07 0.50
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 7.441e-07 0.30
DMPK_HUMAN DMPK Myotonin-protein kinase 8.08e-07 0.41
TTHY_HUMAN TTR Transthyretin 8.749e-07 0.33
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 9.298e-07 0.30
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 9.433e-07 0.32
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.02e-06 0.33
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 1.164e-06 0.41
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.191e-06 0.41
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.64e-06 0.41
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 1.64e-06 0.41
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.914e-06 0.36
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 2.264e-06 0.41
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.264e-06 0.41
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 2.264e-06 0.41
Q7ZJM1_9HIV1 pol Integrase 2.696e-06 0.37
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.069e-06 0.41
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 3.069e-06 0.41
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 3.069e-06 0.41
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 3.069e-06 0.41
NOX4_HUMAN NOX4 NADPH oxidase 4 3.397e-06 0.34
ANDR_HUMAN AR Androgen receptor 4.023e-06 0.46
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 4.093e-06 0.41
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 4.296e-06 0.30
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.586e-06 0.30
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 4.677e-06 0.39
ESR2_HUMAN ESR2 Estrogen receptor beta 5.131e-06 0.36
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 5.375e-06 0.41
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 5.375e-06 0.41
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 5.7e-06 0.28
DPP4_PIG DPP4 Dipeptidyl peptidase 4 6.182e-06 0.40
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 6.602e-06 0.42
AHR_HUMAN AHR Aryl hydrocarbon receptor 6.764e-06 0.46
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 7.503e-06 0.29
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 8.858e-06 0.37
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 8.903e-06 0.41
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 8.903e-06 0.41

Palmidin A

Q9BEG3_BOVIN 5-lipoxygenase 9.139e-75 0.43
AL1A7_RAT Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 1.914e-62 0.47
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 1.662e-50 0.36
ALDH2_RAT Aldh2 Aldehyde dehydrogenase, mitochondrial 7.545e-40 0.32
AGRA_STAAU agrA Accessory gene regulator protein A 1.481e-31 0.46
ACLY_HUMAN ACLY ATP-citrate synthase 4.866e-13 0.32
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 1.018e-08 0.29
TP4A3_HUMAN PTP4A3 Protein tyrosine phosphatase type IVA 3 1.658e-08 0.42

rivularin

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.159e-69 0.42
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.598e-55 0.45
KCNB1_HUMAN KCNB1 Potassium voltage-gated channel subfamily B member 1 9.962e-53 0.35
ACES_RAT Ache Acetylcholinesterase 1.896e-48 0.41
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 7.395e-44 0.67
OPRD_PIG OPRD1 Delta-type opioid receptor 2.269e-41 0.33
TOP1_RAT Top1 DNA topoisomerase 1 2.427e-38 0.30
PRKDC_MOUSE Prkdc DNA-dependent protein kinase catalytic subunit 1.079e-28 0.35
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 4.204e-27 0.44
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.468e-25 0.67
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 4.692e-25 0.40
ARGI1_RAT Arg1 Arginase-1 1.132e-24 0.30
RMLD_MYCTU rmlD dTDP-4-dehydrorhamnose reductase 1.839e-23 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.718e-23 0.46
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 2.847e-23 0.29
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 2.847e-23 0.29
KS6A2_MOUSE Rps6ka2 Ribosomal protein S6 kinase alpha-2 1.95e-20 0.32
BGLR_RAT Gusb Beta-glucuronidase 8.656e-20 0.31
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.466e-19 0.31
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 7.793e-19 0.31
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.242e-17 0.41
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 1.882e-17 0.33
PLGF_HUMAN PGF Placenta growth factor 3.422e-17 0.33
CDC2H_PLAF7 CRK2 Cell division control protein 2 homolog 2.22e-16 0.31
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 2.22e-16 0.43
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 2.22e-16 0.50
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 6.661e-16 0.30
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 3.775e-15 0.38
AMY1A_HUMAN AMY1A Alpha-amylase 1 4.441e-15 0.29
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.921e-14 0.56
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 2.298e-14 0.31
CBS_HUMAN CBS Cystathionine beta-synthase 6.672e-14 0.38
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1e-12 0.33
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.151e-12 0.44
REST_BORBU resT Telomere resolvase ResT 1.761e-12 0.31
ACES_ELEEL ache Acetylcholinesterase 3.198e-12 0.37
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.11e-11 0.35
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.11e-11 0.35
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 5.659e-11 0.29
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 3.274e-10 0.32
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 5.219e-10 0.31
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 6.655e-10 0.31
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 7.414e-10 0.31
CATL2_HUMAN CTSV Cathepsin L2 1.462e-09 0.45
AVR2A_HUMAN ACVR2A Activin receptor type-2A 2.18e-09 0.31
Q49PX0_9POXV N1L N1L 2.37e-09 0.33
Q9BEG3_BOVIN 5-lipoxygenase 2.391e-09 0.33
I3LTK9_PIG CEL Carboxylic ester hydrolase 3.049e-09 0.32
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 7.102e-09 0.31
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 7.31e-09 0.35
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 1.512e-08 0.28
TERT_HUMAN TERT Telomerase reverse transcriptase 1.614e-08 0.41
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 2.082e-08 0.31
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 2.082e-08 0.31
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 3.485e-08 0.31
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 3.793e-08 0.30
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 4.448e-08 0.41
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 5.175e-08 0.31
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 5.175e-08 0.31
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 5.175e-08 0.31
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 5.175e-08 0.31
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 6.118e-08 0.41
MRP2_HUMAN ABCC2 Canalicular multispecific organic anion transporter 1 6.729e-08 0.29
ANDR_HUMAN AR Androgen receptor 7.072e-08 0.43
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 1.155e-07 0.31
NOX4_HUMAN NOX4 NADPH oxidase 4 1.542e-07 0.31
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 2.137e-07 0.31
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.252e-07 0.38
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 4.472e-07 0.31
ACVR1_HUMAN ACVR1 Activin receptor type-1 4.866e-07 0.33
NANH_CLOPF nanH Sialidase 4.974e-07 0.31
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 5.196e-07 0.39
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 5.385e-07 0.32
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.436e-07 0.44
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.473e-07 0.54
ESR2_HUMAN ESR2 Estrogen receptor beta 5.962e-07 0.39
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 6.578e-07 0.32
AVR2B_HUMAN ACVR2B Activin receptor type-2B 7.97e-07 0.31
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 7.97e-07 0.31
CCNT1_HUMAN CCNT1 Cyclin-T1 9.995e-07 0.33
TTHY_HUMAN TTR Transthyretin 1.034e-06 0.31
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 1.077e-06 0.33
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 1.342e-06 0.41
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 2.175e-06 0.31
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 2.322e-06 0.36
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 2.847e-06 0.33
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 2.895e-06 0.36
DPP4_PIG DPP4 Dipeptidyl peptidase 4 2.921e-06 0.44
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 3.377e-06 0.31
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 3.377e-06 0.31
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 4.458e-06 0.32
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 4.478e-06 0.30
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 5.065e-06 0.31
FACE2_HUMAN RCE1 CAAX prenyl protease 2 5.329e-06 0.34
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 6.293e-06 0.33
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 7.112e-06 0.29
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 7.371e-06 0.31

Jaranol

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.618e-68 0.41
VE6_HPV16 E6 Protein E6 3.453e-67 0.44
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 6.213e-67 0.60
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 9.322e-63 0.62
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 7.356e-62 0.46
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.705e-60 0.57
O96394_LEIAM Arginase 1.719e-58 0.44
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.144e-57 0.64
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 3.573e-55 0.44
DDL_HELPH ddl D-alanine--D-alanine ligase 3.573e-55 0.44
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 1.121e-54 0.37
CBS_HUMAN CBS Cystathionine beta-synthase 9.569e-53 0.45
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 6.24e-52 0.50
FAS_CHICK FASN Fatty acid synthase 8.345e-52 0.41
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 3.027e-51 0.41
BGLR_RAT Gusb Beta-glucuronidase 7.659e-47 0.44
TOP1_RAT Top1 DNA topoisomerase 1 5.739e-46 0.37
Q0PJ46_PLAFA LDH Lactate dehydrogenase 1.748e-45 0.30
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.068e-43 0.62
OPRD_PIG OPRD1 Delta-type opioid receptor 1.122e-42 0.34
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.21e-41 0.78
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 3.718e-41 0.44
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.094e-39 0.49
MDHC_PIG MDH1 Malate dehydrogenase, cytoplasmic 2.459e-37 0.30
Q6VVP7_PLAFA Malate dehydrogenase 2.459e-37 0.30
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 3.788e-36 0.38
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.259e-35 0.44
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 3.548e-35 0.44
ACES_RAT Ache Acetylcholinesterase 9.672e-32 0.40
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 2.917e-31 0.61
ARGI1_RAT Arg1 Arginase-1 1.607e-29 0.37
IL2_HUMAN IL2 Interleukin-2 9.044e-29 0.42
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 6.993e-28 0.44
LYSC1_RAT Lyz1 Lysozyme C-1 1.669e-26 0.33
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 5.085e-26 0.32
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 5.373e-26 0.40
R1AB_SARS rep Replicase polyprotein 1ab 1.837e-25 0.44
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.975e-23 0.47
PERL_BOVIN LPO Lactoperoxidase 4.13e-23 0.44
SYN1_BOVIN SYN1 Synapsin-1 7.843e-23 0.37
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.206e-22 0.44
ITF2_HUMAN TCF4 Transcription factor 4 2.532e-22 0.31
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.041e-22 0.44
AMY1A_HUMAN AMY1A Alpha-amylase 1 8.931e-21 0.40
ESR2_HUMAN ESR2 Estrogen receptor beta 3.664e-20 0.58
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 6.172e-20 0.50
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 1.433e-19 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.821e-19 0.69
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 3.333e-19 0.31
NANH_CLOPF nanH Sialidase 3.504e-19 0.44
NOX4_HUMAN NOX4 NADPH oxidase 4 3.733e-19 0.81
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.904e-19 0.47
REST_BORBU resT Telomere resolvase ResT 8.23e-19 0.47
PLGF_HUMAN PGF Placenta growth factor 1.015e-17 0.34
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.281e-17 0.50
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 4.441e-16 0.44
ESR1_HUMAN ESR1 Estrogen receptor 4.441e-16 0.58
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 5.551e-16 0.51
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 6.661e-16 0.90
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 9.992e-16 0.37
DPO1_THEAQ polA DNA polymerase I, thermostable 1.11e-15 0.33
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 3.442e-15 0.33
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 6.883e-15 0.41
EGFR_MOUSE Egfr Epidermal growth factor receptor 3.098e-14 0.31
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 5.085e-14 0.44
MDH_THETH mdh Malate dehydrogenase 1.068e-13 0.44
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.343e-13 0.50
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.187e-13 0.44
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.382e-13 0.37
CAH4_HUMAN CA4 Carbonic anhydrase 4 6.922e-13 0.50
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 6.928e-13 0.62
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 7.849e-13 0.44
LGUL_HUMAN GLO1 Lactoylglutathione lyase 9.97e-13 0.44
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 2.492e-12 0.33
Q7ZJM1_9HIV1 pol Integrase 3.034e-12 0.44
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.577e-12 0.34
ANO1_HUMAN ANO1 Anoctamin-1 3.639e-12 0.35
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 6.039e-12 0.38
CAH3_HUMAN CA3 Carbonic anhydrase 3 7.247e-12 0.44
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 1.082e-11 0.44
TERT_HUMAN TERT Telomerase reverse transcriptase 2.949e-11 0.40
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 9.976e-11 0.31
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 2.525e-10 0.44
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.811e-10 0.83
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 5.036e-10 0.31
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 5.378e-10 0.44
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 5.529e-10 0.31
CAH13_HUMAN CA13 Carbonic anhydrase 13 5.924e-10 0.33
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 7.129e-10 0.44
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.76e-09 0.30
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 2.292e-09 0.33
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 3.465e-09 0.33
ESR1_MOUSE Esr1 Estrogen receptor 3.598e-09 0.29
ESR2_MOUSE Esr2 Estrogen receptor beta 3.598e-09 0.29
CP19A_HUMAN CYP19A1 Aromatase 4.967e-09 0.46
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 5.686e-09 0.64
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 6.085e-09 0.44
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 8.331e-09 0.40
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 8.546e-09 0.56
STXA_SHIDY stxA Shiga toxin subunit A 9.257e-09 0.31
CALM1_HUMAN CALM1 Calmodulin-1 1.528e-08 0.30
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.593e-08 0.50
A4_HUMAN APP Amyloid-beta precursor protein 2.098e-08 0.47
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 2.178e-08 0.30
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.185e-08 0.44
FACE2_HUMAN RCE1 CAAX prenyl protease 2 2.686e-08 0.37
AA1R_RAT Adora1 Adenosine receptor A1 3.207e-08 0.67
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.364e-08 0.41
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 4.468e-08 0.44
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 5.02e-08 0.50
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 5.596e-08 0.40
LRP6_HUMAN LRP6 Low-density lipoprotein receptor-related protein 6 7.387e-08 0.29
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 9.968e-08 0.41
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.365e-07 0.28
DPP4_PIG DPP4 Dipeptidyl peptidase 4 1.937e-07 0.52
ACES_ELEEL ache Acetylcholinesterase 2.986e-07 0.44
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 5.819e-07 0.41
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.14e-06 0.29
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.416e-06 0.44
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.174e-06 0.44
SMO_MOUSE Smo Smoothened homolog 2.195e-06 0.32
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 2.77e-06 0.44
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.36e-06 0.30
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 3.435e-06 0.44
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 4.272e-06 0.34
GPR35_HUMAN GPR35 G-protein coupled receptor 35 5.145e-06 0.44
TTHY_HUMAN TTR Transthyretin 5.998e-06 0.44
IL5_MOUSE Il5 Interleukin-5 6.262e-06 0.31
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 8.629e-06 0.44
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 8.636e-06 0.52
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 8.918e-06 0.30
CAH6_HUMAN CA6 Carbonic anhydrase 6 9.846e-06 0.44

Glycyrol

NANH_CLOPF nanH Sialidase 5.865e-68 0.53
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.901e-60 0.34
TYRO_MOUSE Tyr Tyrosinase 2.248e-45 0.30
A6H249_FLAPJ pop Prolyl oligopeptidase family protein 1.973e-43 0.34
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 8.191e-41 0.36
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 3.293e-40 0.41
NQO1_RAT Nqo1 NAD(P)H dehydrogenase [quinone] 1 3.543e-39 0.31
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.588e-38 0.39
NANH_VIBCH nanH Sialidase 3.554e-36 0.39
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.647e-35 0.39
AOX_TRYBB AOX Alternative oxidase, mitochondrial 3.491e-26 0.30
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 6.102e-25 0.34
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.239e-23 0.29
VE6_HPV16 E6 Protein E6 1.239e-23 0.29
TRPM7_MOUSE Trpm7 Transient receptor potential cation channel subfamily M member 7 8.154e-22 0.35
REST_BORBU resT Telomere resolvase ResT 2.85e-20 0.51
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 2.257e-19 0.35
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 4.372e-18 0.33
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 6.976e-18 0.31
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 8.222e-18 0.29
ESR1_HUMAN ESR1 Estrogen receptor 1.776e-17 0.51
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 3.136e-17 0.36
AOFA_MOUSE Maoa Amine oxidase [flavin-containing] A 1.11e-16 0.32
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.22e-16 0.32
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 5.551e-16 0.35
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 2.665e-15 0.29
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 2.776e-15 0.35
ESR2_HUMAN ESR2 Estrogen receptor beta 5.551e-15 0.51
TYRO_HUMAN TYR Tyrosinase 1.288e-14 0.42
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 3.408e-14 0.31
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 2.122e-13 0.34
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 3.886e-13 0.51
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 2.111e-12 0.30
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 2.955e-12 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.258e-11 0.38
MIF_HUMAN MIF Macrophage migration inhibitory factor 1.214e-09 0.32
TF65_HUMAN RELA Transcription factor p65 1.391e-09 0.48
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.634e-09 0.53
XPO1_HUMAN XPO1 Exportin-1 3.267e-09 0.37
IMDH_CRYNJ Inosine-5'-monophosphate dehydrogenase 4.923e-09 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.015e-08 0.45
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 2.399e-08 0.39
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 2.899e-08 0.51
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.629e-08 0.60
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 6.461e-08 0.39
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 7.964e-08 0.29
CATL2_HUMAN CTSV Cathepsin L2 9.941e-08 0.37
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 2.347e-07 0.48
Q5J463_SALCH tem-1 Beta-lactamase 2.408e-07 0.29
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 2.436e-07 0.35
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.521e-07 0.33
ESR2_RAT Esr2 Estrogen receptor beta 2.713e-07 0.31
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 1.012e-06 0.30
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.192e-06 0.48
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1.221e-06 0.31
ESR1_RAT Esr1 Estrogen receptor 1.263e-06 0.31
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.83e-06 0.31
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 2.205e-06 0.33
IL2_HUMAN IL2 Interleukin-2 3.6e-06 0.32
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 3.777e-06 0.42
CAH13_HUMAN CA13 Carbonic anhydrase 13 3.798e-06 0.30
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 4.103e-06 0.48
PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 4.636e-06 0.45
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 6.261e-06 0.53
NOX4_HUMAN NOX4 NADPH oxidase 4 8.751e-06 0.33
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 8.956e-06 0.29

berberrubine

Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.489e-56 0.71
ACES_ELEEL ache Acetylcholinesterase 6.229e-52 0.80
CHLE_HORSE BCHE Cholinesterase 5.427e-44 0.80
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.699e-40 0.54
RGS17_HUMAN RGS17 Regulator of G-protein signaling 17 1.193e-19 0.31
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.11e-16 0.54
XBP1_RAT Xbp1 X-box-binding protein 1 3.963e-14 0.31
TF_HUMAN F3 Tissue factor 2.635e-09 0.40
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 4.291e-08 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.577e-07 0.80
DRD1_HUMAN DRD1 D(1A) dopamine receptor 7.973e-06 0.40

coptisine

Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.669e-46 0.58
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.352e-39 0.50
ACES_ELEEL ache Acetylcholinesterase 6.074e-38 0.68
CHLE_HORSE BCHE Cholinesterase 5.117e-31 0.68
RGS17_HUMAN RGS17 Regulator of G-protein signaling 17 5.863e-27 0.43
XBP1_RAT Xbp1 X-box-binding protein 1 5.777e-19 0.42
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.887e-15 0.50
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 6.439e-10 0.29
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.132e-07 0.68

Medicarpin

NANH_VIBCH nanH Sialidase 1.051e-43 0.56
NANH_CLOPF nanH Sialidase 9.162e-41 0.77
SECA1_STAA8 secA1 Protein translocase subunit SecA 1 8.275e-39 0.34
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 2.648e-33 0.34
ESR2_HUMAN ESR2 Estrogen receptor beta 4.04e-25 0.42
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.907e-24 0.33
ESR1_HUMAN ESR1 Estrogen receptor 2.658e-23 0.42
FFAR1_RAT Ffar1 Free fatty acid receptor 1 8.16e-18 0.36
5HT5A_RAT Htr5a 5-hydroxytryptamine receptor 5A 1.776e-15 0.30
TYRO_HUMAN TYR Tyrosinase 4.43e-14 0.40
CBS_HUMAN CBS Cystathionine beta-synthase 6.406e-14 0.38
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 6.672e-14 0.30
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.463e-13 0.33
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 2.665e-11 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 7.834e-11 0.34
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 3.509e-10 0.32
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.215e-10 0.36
ANDR_MOUSE Ar Androgen receptor 9.586e-10 0.31
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.431e-09 0.39
OPRX_RAT Oprl1 Nociceptin receptor 8.081e-09 0.35
EDNRB_PIG EDNRB Endothelin receptor type B 1.947e-08 0.32
Q49PX0_9POXV N1L N1L 2.422e-08 0.29
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 5.243e-08 0.37
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 6.944e-08 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.648e-08 0.37
NPCL1_RAT Npc1l1 NPC1-like intracellular cholesterol transporter 1 1.031e-07 0.29
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 1.511e-07 0.29
ESR1_RAT Esr1 Estrogen receptor 3.476e-07 0.34
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.565e-07 0.30
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 5.944e-07 0.33
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 7.692e-07 0.36
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.655e-06 0.29
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 2.089e-06 0.40
Q25270_LEIDO beta-tubulin Beta-tubulin 3.168e-06 0.28
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 5.02e-06 0.29
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 7.562e-06 0.32

Inermine

SECA1_STAA8 secA1 Protein translocase subunit SecA 1 6.218e-38 0.33
NANH_CLOPF nanH Sialidase 1.631e-34 0.78
NANH_VIBCH nanH Sialidase 1.227e-28 0.56
ESR1_RAT Esr1 Estrogen receptor 1.796e-10 0.36
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 1.045e-09 0.28
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.099e-08 0.33
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 7.711e-07 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 1.917e-06 0.42

Berlambine

GPR84_HUMAN GPR84 G-protein coupled receptor 84 8.129e-38 0.35
VE2_HPV1 E2 Regulatory protein E2 2.222e-36 0.29
ACES_ELEEL ache Acetylcholinesterase 6.754e-35 0.48
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.886e-34 0.41
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.313e-32 0.37
CHLE_HORSE BCHE Cholinesterase 1.081e-31 0.48
XBP1_RAT Xbp1 X-box-binding protein 1 1.507e-29 0.67
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.7e-12 0.37
TF_HUMAN F3 Tissue factor 5.311e-12 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.657e-11 0.34
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.669e-11 0.38
ITF2_HUMAN TCF4 Transcription factor 4 1.105e-10 0.29
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 6.291e-10 0.37
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 6.538e-10 0.29
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 3.576e-09 0.29
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.743e-08 0.32
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 3.548e-08 0.29
MK01_RAT Mapk1 Mitogen-activated protein kinase 1 3.985e-08 0.29
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.504e-07 0.30
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.445e-07 0.42
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.731e-07 0.42
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 7.518e-07 0.29
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 9.125e-07 0.39
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 1.263e-06 0.36
EDNRB_HUMAN EDNRB Endothelin receptor type B 2.263e-06 0.38
AVR2B_HUMAN ACVR2B Activin receptor type-2B 2.611e-06 0.29

Worenine

Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.864e-31 0.42
ACES_ELEEL ache Acetylcholinesterase 1.92e-26 0.46
CHLE_HORSE BCHE Cholinesterase 5.835e-22 0.46
RGS17_HUMAN RGS17 Regulator of G-protein signaling 17 2.917e-21 0.34
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 6.721e-21 0.34
XBP1_RAT Xbp1 X-box-binding protein 1 3.042e-14 0.31

5,7,2,5-tetrahydroxy-8,6-dimethoxyflavone

PPME1_HUMAN PPME1 Protein phosphatase methylesterase 1 1.62e-24 0.30
NK1R_MOUSE Tacr1 Substance-P receptor 7.105e-15 0.28

Obacunone

NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 2.887e-15 0.56
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 2.947e-08 0.39