EIF2AK2

Reference Set (71 Compounds)

C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O ZINC000003781738

ZINC000003781738 (search)

COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC ZINC000006745792

ZINC000006745792 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(Cl)c2)c2c(N)ncnc21 ZINC000095552680

ZINC000095552680 (search)

CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 ZINC000003814434

ZINC000003814434 (search)

CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 ZINC000013986815

ZINC000013986815 (search)

$CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C ZINC000003964325$

ZINC000003964325 (search)

Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)c2)c2c(N)ncnc21 ZINC000095550949

ZINC000095550949 (search)

Cn1c(Nc2ccc(C(F)(F)F)cc2)nc2cc(Oc3ccnc(-c4ncc(C(F)(F)F)[nH]4)c3)ccc21 ZINC000018710085

ZINC000018710085 (search)

Cn1cc(-c2cnc(N)c3c(-c4ccc5c(c4)CCN5C(=O)Cc4ccccc4)csc23)cn1 ZINC000095554251

ZINC000095554251 (search)

Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 ZINC000019862646

ZINC000019862646 (search)

CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 ZINC000023247639

ZINC000023247639 (search)

C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl ZINC000035902489

ZINC000035902489 (search)

C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 ZINC000001546066

ZINC000001546066 (search)

$Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 ZINC000018825344$

ZINC000018825344 (search)

Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O ZINC000011617039

ZINC000011617039 (search)

CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)N[C@H]4O ZINC000101364035

ZINC000101364035 (search)

CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21 ZINC000034285211

ZINC000034285211 (search)

CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 ZINC000036056301

ZINC000036056301 (search)

CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 ZINC000003816310

ZINC000003816310 (search)

Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 ZINC000016052569

ZINC000016052569 (search)

O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 ZINC000043201999

ZINC000043201999 (search)

CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 ZINC000021288966

ZINC000021288966 (search)

CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 ZINC000100013130

ZINC000100013130 (search)

CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1 ZINC000003816287

ZINC000003816287 (search)

Cc1cc(C)n(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1 ZINC000096285832

ZINC000096285832 (search)

O=C(O)c1ccc2c3c1cccc3c(=O)n1c3ccccc3nc21 ZINC000000009295

ZINC000000009295 (search)

COC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 ZINC000003776578

ZINC000003776578 (search)

O=C1NC(=O)c2c1c1c3ccccc3[nH]c1n1cncc21 ZINC000014559870

ZINC000014559870 (search)

O=Nc1c(-c2c(O)[nH]c3ccccc23)[nH]c2ccccc12 ZINC000018230030

ZINC000018230030 (search)

$O=C1Nc2ccccc2/C1=C1/Nc2ccccc2/C1=N\OCC[C@H](O)CO ZINC000035052138$

ZINC000035052138 (search)

Cc1[nH]c2ccccc2c1-c1ccnc(Nc2cccnc2)n1 ZINC000072108728

ZINC000072108728 (search)

Cc1[nH]c2ccc(Cl)cc2c1-c1ccnc(Nc2ccc(N3CCN(C)CC3)cc2)n1 ZINC000072109897

ZINC000072109897 (search)

N#C/C(=C1/Nc2ccccc2S1)c1ccnc(NCCc2cccnc2)n1 ZINC000096032364

ZINC000096032364 (search)

CS(=O)(=O)CCCOc1cccc2c1ccn2-c1ccnc(N[C@H]2CC[C@H](C(=O)N3CCC(O)CC3)CC2)n1 ZINC000261146269

ZINC000261146269 (search)

Cc1[nH]c2ccccc2c1-c1ccnc(Nc2ccc(F)cc2)n1 ZINC000072108837

ZINC000072108837 (search)

CCn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc21 ZINC001772820530

ZINC001772820530 (search)

NC(=O)Nc1sc(-c2ccc(F)cc2)cc1C(N)=O ZINC000003960707

ZINC000003960707 (search)

N#Cc1cnc2cnc(NCc3cccnc3)cc2c1Nc1ccc(F)c(Cl)c1 ZINC000020148981

ZINC000020148981 (search)

Cc1[nH]c2ccccc2c1-c1ccnc(Nc2cccc(Cl)c2)n1 ZINC000072109286

ZINC000072109286 (search)

Cn1cc(-c2ccc3c(c2F)CCN3C(=O)Cc2cccc(C(F)(F)F)n2)c2c(N)ncnc21 ZINC000096285831

ZINC000096285831 (search)

$O=C1Nc2cc(Br)ccc2/C1=C1/Nc2ccccc2/C1=N\O ZINC000018128386$

ZINC000018128386 (search)

Cc1[nH]c2ccccc2c1-c1ccnc(Nc2ccc(Cl)cc2)n1 ZINC000072108729

ZINC000072108729 (search)

O=C1NCc2c1c1c3ccccc3n3c1c1c2c2ccccc2n1[C@H]1CC[C@H]3O1 ZINC000101426159

ZINC000101426159 (search)

Cc1cccc(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1 ZINC000096170461

ZINC000096170461 (search)

COc1ccc2[nH]c(C)c(-c3ccnc(NC4CCCC4)n3)c2c1 ZINC000072107061

ZINC000072107061 (search)

Cc1[nH]c2ccccc2c1-c1ccnc(Nc2ccc(F)c(F)c2)n1 ZINC000072108067

ZINC000072108067 (search)

COCCCNc1nccc(-c2c(C)[nH]c3ccccc23)n1 ZINC000072108931

ZINC000072108931 (search)

Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=S)Nc1c(F)cccc1F ZINC000012355112

ZINC000012355112 (search)

CCN(CC)C(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)cc1 ZINC000022309248

ZINC000022309248 (search)

$CSc1cccc(N/C=C2\C(=O)Nc3ccccc32)c1 ZINC000002914165$

ZINC000002914165 (search)

Cc1[nH]c2ccc(Cl)cc2c1-c1ccnc(Nc2cccc(Cl)c2)n1 ZINC000072108115

ZINC000072108115 (search)

CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]3CCCC[C@@H]3N)nc21 ZINC000002583998

ZINC000002583998 (search)

$CN1C(=O)NC(=O)/C(=C\c2c[nH]c3ccc(O)cc23)C1=O ZINC000009341556$

ZINC000009341556 (search)

COCCCNc1nccc(-c2c(C)[nH]c3ccc(Cl)cc23)n1 ZINC000072108819

ZINC000072108819 (search)

Cc1[nH]c2ccccc2c1-c1ccnc(NCCc2c[nH]c3ccccc23)n1 ZINC000072107859

ZINC000072107859 (search)

N#CCCc1ccc2c(c1)[C@H]1Nc3ccc([N+](=O)[O-])cc3[C@@H]1CC(=O)N2 ZINC000072108719

ZINC000072108719 (search)

Nc1cccc(-c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2)c1 ZINC000011757505

ZINC000011757505 (search)

O=C1NC(=O)/C(=C/c2c[nH]c3ccc(Br)cc23)N1 ZINC000013125486

ZINC000013125486 (search)

Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12 ZINC000013816313

ZINC000013816313 (search)

COc1ccc2c(c1)/C(=C/c1c[nH]cn1)C(=O)N2 ZINC000014806879

ZINC000014806879 (search)

O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3cc(Br)ccc3c21 ZINC000003991710

ZINC000003991710 (search)

Nc1[nH]nc2nc3ccccc3nc12 ZINC000005543794

ZINC000005543794 (search)

O=C(O)/C=C/c1cc(Br)c(Br)c(Br)c1Br ZINC000016052815

ZINC000016052815 (search)

Fc1ccc(Nc2nccc(-c3c(-c4ccccc4)[nH]c4ccccc34)n2)cc1 ZINC000072107084

ZINC000072107084 (search)

Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)Nc1c(F)cccc1F ZINC000013645844

ZINC000013645844 (search)

Cc1[nH]c2ccc(Cl)cc2c1-c1ccnc(NC2CCCC2)n1 ZINC000072109159

ZINC000072109159 (search)

Oc1c2ccccc2c2c3c(cccc13)N=N2 ZINC000100706870

ZINC000100706870 (search)

COC(=O)c1ccc2c(-c3ccnc(NCCO)n3)c[nH]c2c1 ZINC000072107271

ZINC000072107271 (search)

$COc1ccc2c(c1)/C(=N\NC(=O)c1cc(Br)ccc1O)C(=O)N2 ZINC000006007277$

ZINC000006007277 (search)

CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C ZINC000000602803

ZINC000000602803 (search)

Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F ZINC000003938688

ZINC000003938688 (search)