PRKAB1

Reference Set (104 Compounds)

CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O ZINC000101595683

ZINC000101595683 (search)

CCn1c2cc(Cl)c(O)cc2c(=O)c2c(=O)o[nH]c21 ZINC000100413014

ZINC000100413014 (search)

Cn1ccc2cc(-c3cc4[nH]c(Oc5cccc(P(=O)(O)O)c5)nc4cc3Cl)ccc21 ZINC000068203291

ZINC000068203291 (search)

Cc1ccc(Oc2nc3nc(-c4ccc(N5CCCC5)cc4)c(Cl)cc3[nH]2)cc1C(=O)O ZINC000143078735

ZINC000143078735 (search)

Cc1ccc(Oc2nc3cc(-c4ccc(-c5ccccc5O)cc4)c(Cl)cc3[nH]2)cc1C(=O)O ZINC000299860692

ZINC000299860692 (search)

COc1ccc(-c2nc3cc(-c4ccc(N5CCCC5)cc4)c(Cl)cc3[nH]2)c(P(=O)(O)O)c1 ZINC000299861744

ZINC000299861744 (search)

Cc1ccc(Oc2nc3cc(-c4ccc(N5CCOCC5)cc4)c(Cl)cc3[nH]2)cc1P(=O)(O)O ZINC000068203302

ZINC000068203302 (search)

O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(-c4ccccc4O)cc3)cc12 ZINC000205302951

ZINC000205302951 (search)

O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(C4(O)CCC4)cc3)cc12 ZINC000205126451

ZINC000205126451 (search)

Cc1ccc(Oc2nc3cc(-c4ccc5c(ccn5C)c4)c(Cl)cc3[nH]2)cc1C(=O)O ZINC000095921139

ZINC000095921139 (search)

CS(=O)(=O)Nc1ccc(-c2ccc(-c3nc4[nH]c(O[C@@H]5CO[C@@H]6[C@H](O)CO[C@H]56)nc4cc3Cl)cc2)c(F)c1 ZINC001772599212

ZINC001772599212 (search)

CC(C)(O)c1ccc(-c2cc3nc(O[C@H]4CO[C@H](CO)[C@@H](O)C4)[nH]c3cc2Cl)cc1 ZINC001772637813

ZINC001772637813 (search)

O=C(O)C1CCC(Oc2nc3c(F)c(-c4ccc5c(ccn5C5CC5)c4)c(F)cc3[nH]2)CC1 ZINC000072316438

ZINC000072316438 (search)

N#Cc1ccc(-c2ccc(-c3nc4nc(O[C@@H]5CO[C@@H]6[C@H](O)CO[C@H]56)[nH]c4cc3Cl)cc2)c(F)c1 ZINC000220840952

ZINC000220840952 (search)

O=C(O)c1c[nH]c2cc(F)c(-c3ccc([C@@H]4CCCCO4)cc3)c(F)c12 ZINC000205355065

ZINC000205355065 (search)

COc1nc(N(C)C)ccc1-c1cc2c(C(=O)O)c[nH]c2cc1Cl ZINC000205355131

ZINC000205355131 (search)

Cc1ccc(Oc2nc3cc(Cl)c(C#Cc4ccccc4)cc3[nH]2)cc1C(=O)O ZINC000200490804

ZINC000200490804 (search)

Cc1ccc(Oc2nc3cc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3[nH]2)cc1C(=O)O ZINC000139295078

ZINC000139295078 (search)

O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc(C4(O)CCC4)cc3)cc12 ZINC000216021864

ZINC000216021864 (search)

Cc1ccc(Oc2nc3cc(-c4ccc(-c5cc[nH]n5)cc4)c(Cl)cc3[nH]2)cc1C(=O)O ZINC000145085998

ZINC000145085998 (search)

Oc1cccc(O)c1-c1ccc(-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)cc1 ZINC001772646860

ZINC001772646860 (search)

O=C(O)CSc1nc2cc(-c3ccc(-c4ccccc4O)cc3)c(Cl)cc2[nH]1 ZINC000118481070

ZINC000118481070 (search)

O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc([C@H]4CCCCO4)cc3)cc12 ZINC000205355149

ZINC000205355149 (search)

O=C(O)c1cc(Oc2nc3cc(C#Cc4ccccc4)c(Cl)cc3[nH]2)ccc1Cl ZINC001772587591

ZINC001772587591 (search)

CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@@H]3CC[C@]12C ZINC000253387933

ZINC000253387933 (search)

O=C(O)[C@H]1C[C@H]1COc1nc2c(F)c(-c3ccc(-c4ccccc4)cc3)c(F)cc2[nH]1 ZINC000072316449

ZINC000072316449 (search)

O=C(O)c1c[nH]c2cc(F)c(-c3ccc(C4(O)CCC4)cc3)c(F)c12 ZINC000205351903

ZINC000205351903 (search)

O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCN4CCOCC4)cc3)cc12 ZINC000205302853

ZINC000205302853 (search)

O=C(O)c1cccc(Sc2nc3cc(-c4ccc(-c5ccccc5O)cc4)c(Cl)cc3[nH]2)c1 ZINC001772574899

ZINC001772574899 (search)

O=C(O)c1cc(Oc2nc3cc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3[nH]2)ccc1Cl ZINC001772654040

ZINC001772654040 (search)

Cc1cc(-c2c(O)[nH]c3cc(Cl)c(-c4ccc(N(C)C)cc4)cc3c2=O)on1 ZINC001772592257

ZINC001772592257 (search)

O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCO)cc3)cc12 ZINC000205306187

ZINC000205306187 (search)

O=C(O)c1c[nH]c2cc(F)c(-c3ccc(C4(O)CCC4)cc3)cc12 ZINC000205351869

ZINC000205351869 (search)

N#Cc1cc2[nH]cc(C(=O)O)c2cc1-c1ccc(C2(O)CCC2)cc1 ZINC000216007128

ZINC000216007128 (search)

O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(CO)cc3)cc12 ZINC000216005316

ZINC000216005316 (search)

COCCOc1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1 ZINC000205299451

ZINC000205299451 (search)

Cn1ccc2cc(-c3cc4nc(SCP(=O)(O)O)[nH]c4cc3Cl)ccc21 ZINC000068207113

ZINC000068207113 (search)

O=C(O)c1cccc(Oc2nc3cc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3[nH]2)c1 ZINC000149841602

ZINC000149841602 (search)

O=C(O)c1c[nH]c2cc(F)c(-c3ccc([C@H]4CCCCO4)cc3)c(F)c12 ZINC000205355082

ZINC000205355082 (search)

N#Cc1c(O)[nH]c2sc(Cl)c(-c3ccc(-c4ccccc4O)cc3)c2c1=O ZINC000036424742

ZINC000036424742 (search)

COc1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1 ZINC000205299531

ZINC000205299531 (search)

O=C(O)COc1nc2cc(Cl)c(C#Cc3ccc(CO)cc3)cc2[nH]1 ZINC000141982841

ZINC000141982841 (search)

CC1(C)C(=O)N([C@H]2CCc3c(O)cccc32)c2nc(Nc3ccccc3)ncc21 ZINC000165569889

ZINC000165569889 (search)

O=C(O)CSc1nc2cc(-c3ccc(-c4ccccc4)cc3)c(Cl)cc2[nH]1 ZINC000118479463

ZINC000118479463 (search)

O=P(O)(O)CSc1nc2cc(-c3ccc(-c4ccc(F)cc4F)cc3)c(Cl)cc2[nH]1 ZINC000299870958

ZINC000299870958 (search)

O=C(O)CSc1nc2cc(C#Cc3ccccc3)c(Cl)cc2[nH]1 ZINC000118483541

ZINC000118483541 (search)

CN(C)c1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cn1 ZINC001772604103

ZINC001772604103 (search)

$Cc1cc(-c2ccc(/C=C3\S/C(=N\c4ccc(Cl)c(C(=O)O)c4)NC3=O)o2)c([N+](=O)[O-])cc1C ZINC000013549354$

ZINC000013549354 (search)

COc1ccc(-c2cc3c(C(=O)O)n[nH]c3cc2Cl)cc1 ZINC000216021077

ZINC000216021077 (search)

N#Cc1c(O)c2c(-c3ccc(-c4ccccc4O)cc3)csc2[nH]c1=O ZINC000019862631

ZINC000019862631 (search)

COc1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)c(OC)n1 ZINC001772590457

ZINC001772590457 (search)

Nc1nc(-c2ccc(-n3c(Cl)cc4[nH]c(=O)n(-c5cccc(C(=O)O)c5)c(=O)c43)cc2)cs1 ZINC000201992672

ZINC000201992672 (search)

$CC(C)/C(=C1\C(=O)N(Cc2cccc(C(=O)O)c2)c2ccccc21)c1ccc(C(F)(F)F)cc1 ZINC000116195810$

ZINC000116195810 (search)

O=C(O)c1cccc(Sc2nc3cc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3[nH]2)c1 ZINC000200490931

ZINC000200490931 (search)

O=C(O)c1cc(N2CCOC2=O)cc(N2C(=O)[C@@]3(C[C@@H]3c3ccc(Cl)cc3)c3ccccc32)c1 ZINC000117674153

ZINC000117674153 (search)

$O=C1/C(=C(\c2ccccc2)c2ccc(Cl)cc2)c2ccccc2N1Cc1ccccc1 ZINC000096270358$

ZINC000096270358 (search)

COc1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cn1 ZINC001772609513

ZINC001772609513 (search)

$O=C(O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccc(Cl)cc3)c3ccccc32)c1 ZINC000096270368$

ZINC000096270368 (search)

O=C(c1ccc2c(c1)C1(CC1)C[C@@H](c1cc(F)ccc1Br)N2)N1CCOCC1 ZINC000112993869

ZINC000112993869 (search)

$O=C(O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccc(Cl)cc3)c3c(F)cccc32)c1 ZINC000116194983$

ZINC000116194983 (search)

O=C(O)c1ccc2c(c1)C1(CC1)C[C@@H](c1cc(Cl)ccc1F)N2 ZINC000148023811

ZINC000148023811 (search)

CC[C@@]1(C)C[C@H](c2ccc(F)c(Cl)c2)Nc2ccc(C(=O)O)nc21 ZINC000112987416

ZINC000112987416 (search)

$O=C1/C(=C/c2ccccn2)CNC/C1=C\c1ccccn1 ZINC000035000883$

ZINC000035000883 (search)

$C(=N/c1cnc2ccccc2c1)\c1ccc2ccccc2n1 ZINC000022910127$

ZINC000022910127 (search)

$O=C(O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccccc3Cl)c3ccccc32)c1 ZINC000096270367$

ZINC000096270367 (search)

CN(C)CCC1CCN(C(=O)c2cccc(N3C(=O)[C@]4(C[C@@H]4c4ccc(Cl)cc4)c4ccccc43)c2)CC1 ZINC000299863637

ZINC000299863637 (search)

$CN1C/C(=C\c2ccccn2)C(=O)/C(=C/c2ccccn2)C1 ZINC000033340364$

ZINC000033340364 (search)

O=C(O)c1csc(Sc2nc3cc(Cl)c(Cl)cc3[nH]2)n1 ZINC001772598202

ZINC001772598202 (search)

O=C(O)Cc1cccc(Sc2nc3cc(Cl)c(Cl)cc3[nH]2)c1 ZINC001772646089

ZINC001772646089 (search)

$O=C(O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3cccnc3)c3ccccc32)c1 ZINC000096270364$

ZINC000096270364 (search)

O=C(O)c1cccc(CN2C(=O)/C(=C/c3ccc(-c4cccc([N+](=O)[O-])c4)o3)c3ccccc32)c1 ZINC000096270371

ZINC000096270371 (search)

COc1ccc(-c2ccc3[nH]nc(C(=O)O)c3c2)cc1 ZINC001772608500

ZINC001772608500 (search)

O=C(O)CSc1nc2cc(Cl)c(Cl)cc2[nH]1 ZINC000001596749

ZINC000001596749 (search)

CC(C)c1ccc(/C(=C2/C(=O)N(Cc3cccc(C(=O)O)c3)c3ccccc32)c2ccccc2)cc1 ZINC000096270366

ZINC000096270366 (search)

$CC(C)NC(=O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccc(Cl)cc3)c3ccccc32)c1 ZINC000096270359$

ZINC000096270359 (search)

O=C(O)c1cccc(CN2C(=O)/C(=C(/c3ccc(Cl)cc3)C3CCCCC3)c3ccccc32)c1 ZINC000096270362

ZINC000096270362 (search)

O=C(O)c1cccc(CN2C(=O)/C(=C/c3ccc(-c4ccc(F)c(Cl)c4)o3)c3ccccc32)c1 ZINC000096270370

ZINC000096270370 (search)

$O=C(O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccc(F)c(Cl)c3)c3ccccc32)c1 ZINC000096270369$

ZINC000096270369 (search)

O=C(O)CCc1nc2cc(-c3ccc(-c4ccccc4)cc3)c(Cl)cc2[nH]1 ZINC000118480887

ZINC000118480887 (search)

O=C(O)c1cccc(Sc2nc3cc(Cl)c(Cl)cc3[nH]2)c1 ZINC001772619278

ZINC001772619278 (search)

$O=C(O)c1cccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccccc3OC(F)(F)F)c3ccccc32)c1 ZINC000096270365$

ZINC000096270365 (search)

O=C(O)CCc1nc2cc(-c3ccccc3)c(Cl)cc2[nH]1 ZINC000118481886

ZINC000118481886 (search)

O=C(O)c1ccccc1Sc1nc2cc(Cl)c(Cl)cc2[nH]1 ZINC001772572128

ZINC001772572128 (search)

O=C(O)CCSc1nc2cc(Cl)c(Cl)cc2[nH]1 ZINC000212950118

ZINC000212950118 (search)

$O=C(O)c1ccc(CN2C(=O)/C(=C(\c3ccccc3)c3ccc(Cl)cc3)c3ccccc32)nc1 ZINC000096270360$

ZINC000096270360 (search)

$CC(C)/C(=C1\C(=O)N(Cc2cccc(C(=O)O)c2)c2ccccc21)c1ccc(Cl)cc1 ZINC000096270363$

ZINC000096270363 (search)

$CN1C/C(=C\c2ccccn2)C(=O)[C@@H](Cc2ccccn2)C1 ZINC000095586371$

ZINC000095586371 (search)

$CN1C/C(=C\c2ccccn2)C(=O)[C@H](Cc2ccccn2)C1 ZINC000095591932$

ZINC000095591932 (search)

CSc1ccccc1Nc1nc(N2CCN(C3CCNCC3)CC2)nc2c(NCC3CC3)ncnc12 ZINC000084654286

ZINC000084654286 (search)

c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)ccn1 ZINC000013829435

ZINC000013829435 (search)

c1ccc2c(-c3cnn4cc(-c5ccc(OCCN6CCOCC6)cc5)cnc34)ccnc2c1 ZINC000062260294

ZINC000062260294 (search)

c1ccc(-c2cnn3cc(-c4ccc(N5CCNCC5)cc4)cnc23)cc1 ZINC000096927001

ZINC000096927001 (search)

CN(C)CCCOc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 ZINC000062260296

ZINC000062260296 (search)

c1ccc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)cc1 ZINC000013819807

ZINC000013819807 (search)

c1cc(N2CCOCC2)ccc1-c1cnc2c(-c3cn[nH]c3)cnn2c1 ZINC000096270778

ZINC000096270778 (search)

COc1ccc(-c2cnc3c(-c4cn[nH]c4)cnn3c2)cc1 ZINC000096270775

ZINC000096270775 (search)

c1cc(N2CCNCC2)ccc1-c1cnc2c(-c3cn[nH]c3)cnn2c1 ZINC000096270776

ZINC000096270776 (search)

O=C(O)c1c[nH]c2ccc(-c3ccc(-c4c(O)cccc4O)cc3)cc12 ZINC000217119160

ZINC000217119160 (search)

CN1CCN(c2ccc(-c3cnc4c(-c5ccnc6ccccc56)cnn4c3)cc2)CC1 ZINC000096270777

ZINC000096270777 (search)

c1ccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1 ZINC000040880920

ZINC000040880920 (search)

N#Cc1ncc2nc1OCCCCOc1cc(NCc3cncs3)c(Cl)cc1NC(=O)N2 ZINC000028963230

ZINC000028963230 (search)

c1cc(-c2cnn3cc(-c4ccc(N5CCNCC5)cc4)cnc23)c2cccnc2c1 ZINC000096173500

ZINC000096173500 (search)

c1ccc2c(-c3cnn4cc(-c5ccc(N6CCOCC6)cc5)cnc34)ccnc2c1 ZINC000096270779

ZINC000096270779 (search)

COc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 ZINC000040401756

ZINC000040401756 (search)