Results of Job: search_066a6189-0c6d-424e-9f10-b0b98651a41e

Query Target Key Target Name Description P-Value MaxTC

Fludarabine

AA1R_RAT Adora1 Adenosine receptor A1 2.571e-281 1.00
AA2AR_RAT Adora2a Adenosine receptor A2a 3.698e-190 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 8.575e-163 1.00
HSF1_MOUSE Hsf1 Heat shock factor protein 1 0.001637 1.00
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 6.654e-195 0.58
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 4.166e-183 0.45
ADK_TOXGO AK Adenosine kinase 6.362e-173 0.68
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 2.228e-172 0.44
AA3R_RAT Adora3 Adenosine receptor A3 1.915e-171 0.74
ADOK_MYCTO adoK Adenosine kinase 1.881e-162 0.41
SAHH_HUMAN AHCY Adenosylhomocysteinase 5.732e-156 0.57
AA1R_CHICK ADORA1 Adenosine receptor A1 2.279e-148 0.54
C3SIU2_ECOLX metJ Met repressor 7.216e-137 0.43
AA1R_RABIT ADORA1 Adenosine receptor A1 5.832e-136 0.44
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 1.119e-134 0.41
AA3R_RABIT ADORA3 Adenosine receptor A3 1.152e-133 0.44
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 8.567e-130 0.51
AA1R_HUMAN ADORA1 Adenosine receptor A1 3.097e-128 0.74
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.435e-123 0.44
AA1R_CAVPO ADORA1 Adenosine receptor A1 3.094e-123 0.74
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 1.852e-117 0.63
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 9.384e-117 0.35
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 5.094e-115 0.35
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 2.516e-113 0.52
SAHH_RAT Ahcy Adenosylhomocysteinase 3.563e-112 0.47
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.354e-104 0.74
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 5.06e-104 0.50
P2RY1_RAT P2ry1 P2Y purinoceptor 1 1.974e-102 0.49
CDD_MOUSE Cda Cytidine deaminase 4.317e-102 0.50
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 2.13e-97 0.49
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 2.355e-96 0.44
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 9.689e-91 0.35
SAHH_MOUSE Ahcy Adenosylhomocysteinase 1.56e-90 0.47
SAHH_PLAF7 Adenosylhomocysteinase 1.045e-89 0.60
ADK_HUMAN ADK Adenosine kinase 4.491e-88 0.68
SPEE_HUMAN SRM Spermidine synthase 3.642e-84 0.43
CDD_HUMAN CDA Cytidine deaminase 2.86e-81 0.42
Q99MI5_RAT LOC100912604 Spermidine synthase 2.849e-76 0.43
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 1.92e-73 0.45
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 1.025e-71 0.46
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 1.296e-71 0.40
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 2.512e-71 0.74
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 2.855e-71 0.44
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 1.113e-70 0.40
RASK_HUMAN KRAS GTPase KRas 5.524e-69 0.37
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 9.404e-69 0.50
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 8.622e-67 0.46
P96884_MYCTO birA BirA bifunctional protein 1.823e-66 0.36
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 3.864e-66 0.43
NADK_HUMAN NADK NAD kinase 4.632e-66 0.46
FUT6_HUMAN FUT6 Alpha-(1,3)-fucosyltransferase 6 8.838e-66 0.31
SPSY_HUMAN SMS Spermine synthase 3.14e-65 0.42
PQSA_PSEAE pqsA Anthranilate--CoA ligase 6.042e-65 0.41
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 3.478e-64 0.41
ADA_MOUSE Ada Adenosine deaminase 8.556e-64 0.42
NADK1_LISMF nadK1 NAD kinase 1 1.697e-63 0.51
NADK_STAAC nadK NAD kinase 1.697e-63 0.51
SAHH2_HUMAN AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 2.952e-61 0.33
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 4.937e-60 0.40
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 6.114e-60 0.38
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 1.225e-59 0.48
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 1.225e-59 0.48
KTHY_HUMAN DTYMK Thymidylate kinase 5.233e-57 0.34
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 6.313e-57 0.48
P2RX5_RAT P2rx5 P2X purinoceptor 5 2.408e-56 0.48
P2RX6_RAT P2rx6 P2X purinoceptor 6 2.408e-56 0.48
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 1.011e-55 0.44
WALK_STAAU walK Sensor protein kinase WalK 1.011e-55 0.44
ENPL_PIG HSP90B1 Endoplasmin 1.696e-55 0.44
SYS_ECOLI serS Serine--tRNA ligase 2.558e-55 0.44
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 6.547e-55 0.47
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 7.269e-55 0.44
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 7.269e-55 0.44
P2RY4_RAT P2ry4 P2Y purinoceptor 4 8.631e-55 0.46
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 1.331e-54 0.39
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 1.573e-54 0.43
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 2.735e-54 0.43
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.634e-53 0.64
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1.668e-53 0.43
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 3.656e-53 0.39
ADA_BOVIN ADA Adenosine deaminase 1.157e-52 0.62
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 4.819e-52 0.35
SYD_ECOLI aspS Aspartate--tRNA ligase 2.789e-51 0.41
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 8.778e-51 0.34
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 1.398e-50 0.40
ADCY2_RAT Adcy2 Adenylate cyclase type 2 3.839e-50 0.44
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 1.017e-49 0.34
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 1.017e-49 0.34
PANE_ECOLI panE 2-dehydropantoate 2-reductase 5.443e-49 0.31
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 7.227e-49 0.39
ENTE_ECOLI entE Enterobactin synthase component E 8.02e-49 0.31
SYY_ECOLI tyrS Tyrosine--tRNA ligase 5.765e-48 0.38
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 3.01e-47 0.44
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 9.288e-47 0.37
Q4VQ11_PIG Adenosine receptor A1 1.187e-44 0.55
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 3.774e-44 0.35
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 1.756e-43 0.35
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 3.711e-42 0.36
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.732e-41 0.68
Q8TA74_HEMPU Ryanodine receptor 3.934e-40 0.33
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 9.023e-39 0.48
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 1.089e-38 0.33
POLG_POL1M Genome polyprotein 4.536e-38 0.30
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 6.303e-38 0.43
S28A2_RAT Slc28a2 Sodium/nucleoside cotransporter 2 2.333e-36 0.29
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 2.619e-36 0.42
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 3.788e-36 0.38
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3.875e-36 0.29
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 6.36e-36 0.36
ENTP1_BOVIN ENTPD1 Ectonucleoside triphosphate diphosphohydrolase 1 1.71e-35 0.28
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 2.005e-34 0.63
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 2.601e-34 0.43
SYL_ECOLI leuS Leucine--tRNA ligase 5.293e-34 0.42
ADA_HUMAN ADA Adenosine deaminase 4.958e-33 0.60
Q9HX69_PSEAE rocR RocR 5.95e-33 0.34
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 7.448e-33 0.42
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 5.025e-32 0.33
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 5.025e-32 0.33
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.118e-31 0.36
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 1.512e-30 0.28
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 4.851e-30 0.39
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 5.015e-30 0.48
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 2.986e-29 0.48
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1.385e-28 0.44
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 2.3e-28 0.35
PUR6_CHICK AIRC Multifunctional protein ADE2 4.874e-28 0.34
AMPD1_RABIT AMPD1 AMP deaminase 1 7.994e-28 0.34
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 2.247e-27 0.34
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 8.491e-27 0.45
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 9.136e-27 0.74
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 1.182e-26 0.42
AA2AR_MOUSE Adora2a Adenosine receptor A2a 1.283e-26 0.30
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 1.646e-26 0.35
P2RX4_RAT P2rx4 P2X purinoceptor 4 4.81e-26 0.48
AA1R_BOVIN ADORA1 Adenosine receptor A1 7.719e-26 0.74
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.453e-25 0.49
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 3.051e-25 0.34
SYI_ECOLI ileS Isoleucine--tRNA ligase 4.411e-25 0.40
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 5.693e-25 0.45
BPL1_HUMAN HLCS Biotin--protein ligase 1.533e-24 0.35
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 2.52e-24 0.48
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 3.022e-24 0.39
PANC_MYCTU panC Pantothenate synthetase 3.943e-24 0.44
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 5.682e-24 0.44
Q3ZDS5_9HEPC NS5B 1.069e-23 0.29
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 1.114e-23 0.29
KITH_RAT Tk1 Thymidine kinase, cytosolic 1.551e-22 0.36
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.666e-22 0.47
P2RX1_RAT P2rx1 P2X purinoceptor 1 6.553e-22 0.46
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 8.283e-22 0.51
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 2.303e-21 0.51
KITH_VZVD TK Thymidine kinase 3.057e-21 0.32
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 6.242e-20 0.33
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 2.375e-18 0.29
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 4.377e-18 0.45
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 1.243e-17 0.44
B4EH87_BURCJ Lectin 1.11e-16 0.32
5NTD_HUMAN NT5E 5'-nucleotidase 2.22e-16 0.47
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 9.992e-16 0.33
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 1.11e-15 0.35
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 1.221e-15 0.41
OGA_HUMAN OGA Protein O-GlcNAcase 5.884e-15 0.32
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 2.542e-14 0.44
AA1R_MOUSE Adora1 Adenosine receptor A1 2.931e-14 0.53
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 4.874e-14 0.42
KITH_HUMAN TK1 Thymidine kinase, cytosolic 5.551e-14 0.33
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 5.74e-14 0.48
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.239e-13 0.41
OGA_RAT Oga Protein O-GlcNAcase 3.084e-13 0.29
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 3.427e-13 0.42
CD69_HUMAN CD69 Early activation antigen CD69 3.773e-13 0.32
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.773e-13 0.32
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 4.547e-13 0.35
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 4.751e-13 0.42
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 6.268e-13 0.38
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 7.736e-13 0.32
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 1.146e-12 0.40
CCNK_HUMAN CCNK Cyclin-K 1.714e-12 0.34
AA3R_MOUSE Adora3 Adenosine receptor A3 2.783e-12 0.31
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 4.94e-12 0.44
P2RX2_RAT P2rx2 P2X purinoceptor 2 1.161e-11 0.48
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.246e-11 0.45
ADK_RAT Adk Adenosine kinase 1.399e-11 0.55
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 6.023e-11 0.29
E1BN64_BOVIN PDE3B Phosphodiesterase 3.596e-10 0.34
LEG1_HUMAN LGALS1 Galectin-1 5.371e-10 0.28
TYPH_HUMAN TYMP Thymidine phosphorylase 5.714e-10 0.34
INMT_HUMAN INMT Indolethylamine N-methyltransferase 6.069e-10 0.44
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 9.827e-10 0.39
DCPS_HUMAN DCPS m7GpppX diphosphatase 1.145e-09 0.41
DPOLB_HUMAN POLB DNA polymerase beta 1.165e-09 0.31
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.707e-09 0.32
5NTD_RAT Nt5e 5'-nucleotidase 1.778e-09 0.47
P2Y12_RAT P2ry12 P2Y purinoceptor 12 5.797e-09 0.48
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.315e-08 0.44
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 1.557e-08 0.39
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.138e-08 0.33
SYT_YERPE thrS Threonine--tRNA ligase 3.442e-08 0.41
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 3.495e-08 0.47
LEG3_HUMAN LGALS3 Galectin-3 5.537e-08 0.28
EZH2_HUMAN EZH2 Histone-lysine N-methyltransferase EZH2 5.666e-08 0.44
ENPL_CANLF HSP90B1 Endoplasmin 7.105e-08 0.44
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.123e-07 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.689e-07 0.34
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 2.815e-07 0.45
LUCI_AQULA Luciferin 4-monooxygenase 4.503e-07 0.35
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 4.858e-07 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.266e-07 0.34
DNLJ_STAAU ligA DNA ligase 5.605e-07 0.64
PNPH_HUMAN PNP Purine nucleoside phosphorylase 7.44e-07 0.43
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.292e-06 0.45
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 2.098e-06 0.44
Q56950_YERPE ybtE Salicyl-AMP ligase YbtE 3.423e-06 0.40
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 3.629e-06 0.68
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 4.003e-06 0.30
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 4.055e-06 0.44

Irbesartan

AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 5.541e-277 1.00
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 1.544e-126 1.00
EDNRA_HUMAN EDNRA Endothelin-1 receptor 7.059e-07 1.00
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 1.213e-218 0.52
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 2.061e-201 0.56
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 4.588e-139 0.51
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 6.249e-66 0.45
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.138e-54 0.62
A8K2H7_HUMAN C3AR1 Complement component 3a receptor 1, isoform CRA_a 2.643e-49 0.33
GHSR_PIG GHSR Growth hormone secretagogue receptor type 1 1.225e-37 0.30
GPVI_HUMAN GP6 Platelet glycoprotein VI 1.201e-30 0.38
ACATN_HUMAN SLC33A1 Acetyl-coenzyme A transporter 1 3.896e-22 0.31
POLI_HUMAN POLI DNA polymerase iota 6.155e-22 0.35
AGTR1_CAVPO AGTR1 Type-1 angiotensin II receptor 6.809e-21 0.51
POLK_HUMAN POLK DNA polymerase kappa 3.22e-14 0.35
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.901e-13 0.29
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 4.598e-12 0.33
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 2.254e-09 0.33
ACES_RAT Ache Acetylcholinesterase 2.638e-08 0.71
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.827e-06 0.28

Fluvastatin

HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.782e-259 1.00
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.021e-213 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.2713 1.00
HMDH_MOUSE Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.917e-64 0.41
HMDH_PIG HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.765e-28 0.45
FABP4_RAT Fabp4 Fatty acid-binding protein, adipocyte 2.847e-23 0.29
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.664e-15 0.45
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 3.099e-12 0.45
AK1A1_HUMAN AKR1A1 Aldo-keto reductase family 1 member A1 1.38e-09 0.32
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 2.567e-07 0.30
CENPE_HUMAN CENPE Centromere-associated protein E 3.098e-07 0.31
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 3.431e-07 0.32
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 1.074e-06 0.34
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.363e-06 0.30
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.827e-06 0.29
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 4.204e-06 0.31
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.596e-06 0.29
APJ_HUMAN APLNR Apelin receptor 6.947e-06 0.30

Rosuvastatin

HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.473e-253 1.00
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 9.2e-194 1.00
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 3.215e-07 1.00
HMDH_MOUSE Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.156e-62 0.41
HMDH_PIG HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.025e-20 0.33
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 4.877e-07 0.33

Ketoconazole

CP21A_HUMAN CYP21A2 Steroid 21-hydroxylase 5.862e-248 1.00
CP11A_RAT Cyp11a1 Cholesterol side-chain cleavage enzyme, mitochondrial 2.335e-181 1.00
CP7A1_RAT Cyp7a1 Cytochrome P450 7A1 2.335e-181 1.00
CP3A5_HUMAN CYP3A5 Cytochrome P450 3A5 2.9e-124 1.00
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 8.86e-120 1.00
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 8.54e-64 1.00
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 1.466e-51 1.00
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.937e-30 1.00
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.599e-23 1.00
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.176e-19 1.00
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 2.026e-18 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.992e-16 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 8.327e-15 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 3.771e-13 1.00
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 4.222e-09 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.934e-08 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 9.221e-07 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.282e-06 1.00
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 0.0001102 1.00
CP19A_HUMAN CYP19A1 Aromatase 0.0001338 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0003946 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.0009778 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 0.001409 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.005765 1.00
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 0.0206 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.04806 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.05954 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.09618 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.6236 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.7193 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.8309 1.00
HMOX1_RAT Hmox1 Heme oxygenase 1 5.899e-120 0.50
CP51A_ASPFU cyp51A 14-alpha sterol demethylase Cyp51A 5.265e-54 0.56
Q96W81_ASPFM cyp51B 14-alpha sterol demethylase 7.03e-45 0.56
HMOX2_RAT Hmox2 Heme oxygenase 2 3.025e-43 0.50
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 9.916e-38 0.32
HMOX1_HUMAN HMOX1 Heme oxygenase 1 1.476e-29 0.37
CP121_MYCTU cyp121 Mycocyclosin synthase 3.317e-24 0.30
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 1.673e-23 0.29
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 1.104e-19 0.30
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 1.11e-15 0.30
ALK_HUMAN ALK ALK tyrosine kinase receptor 7.216e-15 0.36
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 3.4e-12 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.609e-09 0.30
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 6.591e-08 0.31
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.78e-07 0.32
FA10_HUMAN F10 Coagulation factor X 2.933e-07 0.35
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 4.259e-07 0.34
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 2.042e-06 0.39
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 4.993e-06 0.30
THAS_RAT Tbxas1 Thromboxane-A synthase 7.971e-06 0.32

Mycophenolic_acid

IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 5.392e-245 1.00
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 7.761e-170 1.00
IMDH_CRYNJ Inosine-5'-monophosphate dehydrogenase 3.59e-28 1.00
AOX_TRYBB AOX Alternative oxidase, mitochondrial 4.836e-47 0.38
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 2.659e-10 0.30
NANH_CLOPF nanH Sialidase 4.677e-09 0.32
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 4.633e-08 0.30
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 3.629e-07 0.29
ACPM_BOVIN NDUFAB1 Acyl carrier protein, mitochondrial 9.331e-07 0.30
NDUV1_BOVIN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 9.331e-07 0.30

Topotecan

TOP1_HUMAN TOP1 DNA topoisomerase 1 7.262e-233 1.00
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.937e-30 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
GLF_MYCTU glf UDP-galactopyranose mutase 9.259e-14 1.00
O40947_HHV8 ORF 73 1.702e-08 1.00
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 8.415e-05 1.00
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 0.00132 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 0.003241 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.392e-17 0.53
TOP1_MOUSE Top1 DNA topoisomerase 1 4.627e-17 0.66
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 5.031e-10 0.34

Novobiocin

GYRB_ECOLI gyrB DNA gyrase subunit B 1.975e-222 1.00
C3SLN2_ECOLX gyrB DNA gyrase subunit B 3.29e-75 1.00
Q47245_ECOLX gyrA DNA gyrase subunit A 1.089e-50 1.00
GYRB_MYCS2 gyrB DNA gyrase subunit B 9.163e-22 1.00
C3SLN3_ECOLX gyrB DNA gyrase subunit B 8.882e-16 1.00
GYRB_STRPN gyrB DNA gyrase subunit B 9.469e-13 1.00
Q7X1P7_STREE parE DNA topoisomerase (ATP-hydrolyzing) 9.469e-13 1.00
GYRA_STAAU gyrA DNA gyrase subunit A 4.783e-07 1.00
GYRB_MYCSM gyrB DNA gyrase subunit B 9.294e-06 1.00
GYRB_STAAU gyrB DNA gyrase subunit B 0.0002197 1.00
NANH_VIBCH nanH Sialidase 7.229e-31 0.32
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 9.096e-25 0.30
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 1.11e-16 0.73
DCOR_HUMAN ODC1 Ornithine decarboxylase 9.573e-08 0.29
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 2.917e-07 0.36
NANH_CLOPF nanH Sialidase 6.445e-07 0.32

Atorvastatin

HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 8.256e-222 1.00
HMDH_PIG HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.121e-61 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.472e-31 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9174 1.00
HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.93e-263 0.72
HMDH_MOUSE Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.788e-49 0.32
CCR3_MACFA CCR3 C-C chemokine receptor type 3 7.142e-37 0.29
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.116e-25 0.34
PRIO_SHEEP PRNP Major prion protein 3.192e-24 0.31
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 3.392e-21 0.76
MMP3_HUMAN MMP3 Stromelysin-1 4.996e-15 0.37
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 4.744e-13 0.32
APJ_HUMAN APLNR Apelin receptor 4.948e-11 0.30
Q6DMN0_TOXGO CPL Cathepsin L 2.659e-10 0.30
GALR1_RAT Galr1 Galanin receptor type 1 4.325e-10 0.29
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.13e-10 0.31
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.202e-09 0.34
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 2.355e-09 0.31
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 2.563e-09 0.30
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 3.244e-09 0.28
VE1_HPV11 E1 Replication protein E1 5.158e-09 0.31
ITB7_HUMAN ITGB7 Integrin beta-7 1.742e-08 0.32
MMP2_HUMAN MMP2 72 kDa type IV collagenase 2.33e-08 0.37
CASP1_MOUSE Casp1 Caspase-1 4.167e-08 0.35
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.703e-07 0.31
MMP1_HUMAN MMP1 Interstitial collagenase 2.191e-07 0.37
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.729e-07 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.729e-07 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.864e-07 0.30
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.221e-07 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 6.705e-07 0.31
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.499e-06 0.29
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 3.31e-06 0.28
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 3.488e-06 0.29
ANO1_HUMAN ANO1 Anoctamin-1 5.635e-06 0.30

Atazanavir

Q72874_9HIV1 pol Pol polyprotein 1.179e-184 1.00
Q9YQ12_9HIV1 protease Protease 1.724e-147 1.00
O90781_9PLVG HIV-1 protease HIV-1 protease 2.72e-133 1.00
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 1.266e-14 1.00
Q82134_9DELA prt Protease 1.317e-146 0.36
POL_HV1A2 gag-pol Gag-Pol polyprotein 1.699e-100 0.32
Q82323_9DELA Protease 1.263e-94 0.31
PLM1_PLAFA Plasmepsin-1 1.952e-74 0.40
RENI_HUMAN REN Renin 7.092e-62 0.38
CATL1_BOVIN CTSL Cathepsin L1 1.079e-58 0.36
PRO_HTL1A gag-pro Gag-Pro polyprotein 2.921e-54 0.31
CATD_HUMAN CTSD Cathepsin D 1.146e-46 0.58
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 3.331e-45 0.37
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 3.331e-45 0.37
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 3.331e-45 0.37
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 3.331e-45 0.37
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 3.331e-45 0.37
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 3.331e-45 0.37
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 3.331e-45 0.37
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 3.331e-45 0.37
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 3.331e-45 0.37
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 3.331e-45 0.37
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 3.331e-45 0.37
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 3.331e-45 0.37
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 3.331e-45 0.37
PLM2_PLAFA Plasmepsin-2 1.529e-44 0.40
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 9.438e-44 0.37
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 5.23e-37 0.37
CANX_CHICK Calpain-1 catalytic subunit 1.71e-35 0.28
PEPA_PIG PGA Pepsin A 3.294e-34 0.40
PEPC_HUMAN PGC Gastricsin 6.359e-32 0.40
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 3.612e-31 0.37
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 8.778e-31 0.37
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 7.189e-30 0.37
CATD_BOVIN CTSD Cathepsin D 8.551e-30 0.40
PEPT1_DERPT DERP1 Peptidase 1 1.17e-24 0.32
CARP_YEAST PEP4 Saccharopepsin 1.535e-24 0.30
PAPA1_CARPA Papain 6.042e-24 0.36
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.165e-23 0.32
UROK_RAT Plau Urokinase-type plasminogen activator 5.225e-23 0.28
Q3HTL5_PLAFA fp2B Falcipain 2B 7.318e-23 0.28
KLK5_HUMAN KLK5 Kallikrein-5 1.209e-21 0.39
Q4U254_9ENTO protease Protease 2.868e-21 0.40
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 6.747e-21 0.31
P88142_9HIV2 pol Pol polyprotein 2.843e-19 0.29
RENI_RAT Ren1 Renin 5.229e-19 0.34
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.022e-18 0.31
NK3R_CAVPO TACR3 Neuromedin-K receptor 9.992e-16 0.31
BACE1_HUMAN BACE1 Beta-secretase 1 1.221e-15 0.37
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.044e-14 0.34
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 1.377e-14 0.32
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.587e-14 0.37
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.188e-13 0.29
UROK_MOUSE Plau Urokinase-type plasminogen activator 5.476e-13 0.28
CATF_HUMAN CTSF Cathepsin F 4.07e-12 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.822e-11 0.35
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 5.617e-11 0.33
RENI1_MOUSE Ren1 Renin-1 9.872e-11 0.29
CATB_HUMAN CTSB Cathepsin B 2.347e-10 0.37
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 5.06e-10 0.43
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 5.06e-10 0.43
NICA_HUMAN NCSTN Nicastrin 5.06e-10 0.43
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 5.109e-10 0.43
PSN2_HUMAN PSEN2 Presenilin-2 5.256e-10 0.43
CARP_RHICH Rhizopuspepsin 6.811e-10 0.31
POL_HV1BR gag-pol Gag-Pol polyprotein 9.521e-10 0.30
MMP3_HUMAN MMP3 Stromelysin-1 1.181e-09 0.32
GLNA_HUMAN GLUL Glutamine synthetase 1.206e-09 0.30
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.206e-09 0.30
PSN1_HUMAN PSEN1 Presenilin-1 1.265e-09 0.43
ECE1_RAT Ece1 Endothelin-converting enzyme 1 4.329e-09 0.29
NEP_HUMAN MME Neprilysin 8.465e-09 0.31
CATE_HUMAN CTSE Cathepsin E 8.732e-09 0.40
BACE2_HUMAN BACE2 Beta-secretase 2 8.769e-09 0.30
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 9.565e-09 0.38
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.877e-08 0.30
NK2R_MESAU TACR2 Substance-K receptor 1.994e-08 0.30
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 7.772e-08 0.32
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.436e-07 0.33
CYSP_TRYCR Cruzipain 2.418e-07 0.32
Q95PM0_TRYBR rhodesain Cysteine protease 3.229e-07 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 2.535e-06 0.32
NK3R_RAT Tacr3 Neuromedin-K receptor 3.536e-06 0.30
MMP2_HUMAN MMP2 72 kDa type IV collagenase 3.923e-06 0.31
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 7.219e-06 0.32
CAN1_RAT Capn1 Calpain-1 catalytic subunit 8.684e-06 0.28
Q9JN24_ECOLX def Peptide deformylase 9.831e-06 0.32

Rifampin

RPOB_MYCTU rpoB DNA-directed RNA polymerase subunit beta 2.207e-176 1.00
SO1B3_HUMAN SLCO1B3 Solute carrier organic anion transporter family member 1B3 8.085e-104 1.00
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 1.454e-74 1.00
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.301e-08 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.06e-05 1.00
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 0.0002138 1.00
CASP1_HUMAN CASP1 Caspase-1 0.03466 1.00
STRP_STRP1 ska Streptokinase A 0.2233 1.00
POL_WMSV pol Gag-Pol polyprotein 2.078e-188 0.74
DPOLB_MOUSE Polb DNA polymerase beta 2.775e-114 0.64
SO2B1_HUMAN SLCO2B1 Solute carrier organic anion transporter family member 2B1 1.192e-88 0.71
ABCBB_RAT Abcb11 Bile salt export pump 5.089e-28 0.71
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.22e-16 0.71
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.632e-14 0.71

Gabapentin

O77773_PIG Voltage-dependent calcium channel alpha-2 delta subunit 1.904e-173 1.00
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.996e-24 1.00
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.337e-10 1.00
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.18e-05 1.00

Exemestane

CP19A_HUMAN CYP19A1 Aromatase 4.148e-147 1.00
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.563e-66 0.44
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.044e-56 0.44
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.83e-48 0.44
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 4.211e-44 0.41
SHBG_HUMAN SHBG Sex hormone-binding globulin 9.725e-41 0.44
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.089e-29 0.39
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 2.388e-29 0.39
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 1.908e-25 0.31
Q690N0_BOVIN PGR Progesterone receptor 3.679e-25 0.38
SHBG_RAT Shbg Sex hormone-binding globulin 3.794e-24 0.30
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.519e-23 0.36
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 1.803e-22 0.36
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.717e-21 0.39
STS_HUMAN STS Steryl-sulfatase 1.351e-20 0.38
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.426e-19 0.32
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.556e-18 0.28
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 7.542e-18 0.37
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 3.081e-17 0.39
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.73e-14 0.30
ANDR_RAT Ar Androgen receptor 9.914e-14 0.44
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.905e-13 0.39
ERG2_YEAST ERG2 C-8 sterol isomerase 3.635e-12 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.296e-11 0.39
GLNA_HUMAN GLUL Glutamine synthetase 2.795e-10 0.32
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.43e-10 0.39
IL6_HUMAN IL6 Interleukin-6 3.167e-08 0.32
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.067e-07 0.36
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.732e-06 0.30
GCR_MOUSE Nr3c1 Glucocorticoid receptor 5.203e-06 0.32
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 5.807e-06 0.44

Isoprenaline

ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 6.57e-146 1.00
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.054e-77 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.492e-77 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.179e-74 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.057e-74 1.00
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 6.054e-63 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.619e-53 1.00
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.078e-51 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.219e-49 1.00
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 6.524e-44 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.116e-36 1.00
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 6.953e-35 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.375e-10 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.04189 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.1061 1.00
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 3.487e-68 0.55
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 3.487e-68 0.55
Q06347_9HIV2 reverse transcriptase Reverse transcriptase 1.431e-47 0.38
ADRB3_MOUSE Adrb3 Beta-3 adrenergic receptor 1.122e-42 0.34
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 3.682e-30 0.29
Q39829_SOYBN Lipoxygenase 3.022e-24 0.39
H9TVJ1_CHISP TyR1 3.516e-24 0.30
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 1.444e-23 0.29
G3HDX1_CRIGR Alpha-1B adrenergic receptor 2.751e-21 0.41
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.808e-18 0.39
TYRO_HUMAN TYR Tyrosinase 2.22e-15 0.33
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 8.66e-15 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.464e-14 0.69
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.335e-13 0.31
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 2.583e-13 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.167e-13 0.42
RNH1_HUMAN RNASEH1 Ribonuclease H1 8.722e-13 0.38
COMT_PIG COMT Catechol O-methyltransferase 3.598e-09 0.29
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 4.34e-09 0.69
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 6.365e-09 0.30
Q49PX0_9POXV N1L N1L 1.083e-08 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 9.872e-08 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.427e-07 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.639e-06 0.39
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 7.376e-06 0.39

Metyrapone

C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 3.018e-134 1.00
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 4.449e-17 1.00
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 9.598e-08 1.00
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.321e-05 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.0001345 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.236e-55 0.42
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.127e-33 0.40
CP19A_RAT Cyp19a1 Aromatase 4.899e-30 0.45
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.279e-21 0.43
KLK14_HUMAN KLK14 Kallikrein-14 5.19e-19 0.30
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 3.59e-17 0.34
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 7.438e-15 0.34
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 1.033e-14 0.37
ACES_ANOGA Ace Acetylcholinesterase 1.332e-14 0.38
ABCC9_HUMAN ABCC9 ATP-binding cassette sub-family C member 9 8.149e-14 0.32
CYSP_PLAFA Trophozoite cysteine proteinase 5.411e-13 0.38
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.315e-12 0.31
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 1.132e-11 0.33
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 1.717e-11 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 5.76e-11 0.33
FA12_HUMAN F12 Coagulation factor XII 7.21e-11 0.32
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.738e-10 0.39
O96526_LEIMA CRK3 Cdc2-related kinase 5.162e-10 0.29
PPO1_AGABI PPO1 Polyphenol oxidase 1 1.582e-09 0.30
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.416e-09 0.31
TA2R_RAT Tbxa2r Thromboxane A2 receptor 3.419e-09 0.36
POLG_HCV77 Genome polyprotein 4.037e-09 0.33
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 5.722e-09 0.36
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 3.189e-08 0.29
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 6.992e-08 0.32
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 1.193e-07 0.28
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.362e-07 0.29
PGLD_CAMJE pglD UDP-N-acetylbacillosamine N-acetyltransferase 4.061e-07 0.29
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 5.858e-07 0.38
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 6.554e-07 0.32
MIP_LEGPN mip Outer membrane protein MIP 1.166e-06 0.28
KLK5_HUMAN KLK5 Kallikrein-5 1.385e-06 0.30
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.694e-06 0.30
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 1.944e-06 0.28
Q76129_9HIV1 gag Structural capsid protein 2.548e-06 0.33
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.587e-06 0.36
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.678e-06 0.48
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 4.23e-06 0.30

Orlistat

ABD12_HUMAN ABHD12 Lysophosphatidylserine lipase ABHD12 2.9e-124 1.00
ABHGA_HUMAN ABHD16A Phosphatidylserine lipase ABHD16A 2.9e-124 1.00
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.195e-113 1.00
LIPP_HUMAN PNLIP Pancreatic triacylglycerol lipase 5.121e-61 1.00
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 5.442e-43 1.00
DGLB_HUMAN DAGLB Sn1-specific diacylglycerol lipase beta 2.191e-35 1.00
DGLA_MOUSE Dagla Sn1-specific diacylglycerol lipase alpha 1.645e-26 1.00
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.584e-12 1.00
FAS_HUMAN FASN Fatty acid synthase 1.242e-05 1.00
CNR1_HUMAN CNR1 Cannabinoid receptor 1 0.00449 1.00
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 0.004684 1.00
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 0.008309 1.00
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 8.016e-45 0.35
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.258e-27 0.36
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 4.774e-25 0.36
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 6.474e-25 0.31
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 7.84e-23 0.31
ACPM_BOVIN NDUFAB1 Acyl carrier protein, mitochondrial 1.438e-21 0.32
NDUV1_BOVIN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 1.438e-21 0.32
CLPP_STAA8 clpP ATP-dependent Clp protease proteolytic subunit 3.983e-19 0.30
ACLY_RAT Acly ATP-citrate synthase 2.22e-16 0.35
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 2.22e-16 0.36
KPCA_RAT Prkca Protein kinase C alpha type 3.22e-15 0.31
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 8.66e-14 0.34
Q6UB75_PIG Group VII phospholipase A2 2.562e-13 0.29
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.106e-12 0.36
LASR_PSEAE lasR Transcriptional activator protein LasR 3.244e-12 0.30
TRAR_RHIRD traR Transcriptional activator protein TraR 6.013e-11 0.28
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 9.638e-11 0.34
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.416e-10 0.29
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 2.783e-10 0.29
LUXR_ALIFS luxR Transcriptional activator protein LuxR 6.396e-10 0.28
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.175e-08 0.36
CATB_BOVIN CTSB Cathepsin B 2.357e-08 0.29
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 7.748e-08 0.32
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.664e-07 0.29
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.645e-07 0.28
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 6.83e-07 0.29
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 1.239e-06 0.34

Ouabain

AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 2.9e-124 1.00
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 5.128e-114 1.00
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 5.128e-114 1.00
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 2.326e-91 1.00
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 1.133e-82 1.00
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 2.714e-79 1.00
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.879e-12 1.00
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 7.033e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
NOTC1_MOUSE Notch1 Neurogenic locus notch homolog protein 1 5.745e-80 0.46
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 4.439e-78 0.47
AT1A1_HUMAN ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1.207e-69 0.44
AT1A1_PIG ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 2.457e-54 0.34
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 8.579e-52 0.47
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 1.289e-19 0.44
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 3.331e-16 0.39
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 6.747e-11 0.42
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.052e-06 0.72

Isotretinoin

RABP1_CHICK CRABP1 Cellular retinoic acid-binding protein 1 1.617e-112 1.00
RARA_MOUSE Rara Retinoic acid receptor alpha 9.843e-97 1.00
RARG_MOUSE Rarg Retinoic acid receptor gamma 2.904e-90 1.00
RARB_MOUSE Rarb Retinoic acid receptor beta 4.049e-78 1.00
RXRG_HUMAN RXRG Retinoic acid receptor RXR-gamma 4.529e-66 1.00
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 2.416e-65 1.00
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 2.12e-64 1.00
RXRB_HUMAN RXRB Retinoic acid receptor RXR-beta 1.093e-59 1.00
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 1.555e-57 1.00
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 3.893e-53 1.00
RXRA_RAT Rxra Retinoic acid receptor RXR-alpha 1.786e-51 1.00
RARG_HUMAN RARG Retinoic acid receptor gamma 2.933e-51 1.00
RARB_HUMAN RARB Retinoic acid receptor beta 3.165e-36 1.00
RARA_HUMAN RARA Retinoic acid receptor alpha 1.624e-32 1.00
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 1.415e-08 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 0.07802 1.00
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 0.1022 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.4773 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 0.9551 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.9676 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9869 1.00
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 0.9941 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
RABP2_MOUSE Crabp2 Cellular retinoic acid-binding protein 2 3.946e-107 0.53
RABP1_MOUSE Crabp1 Cellular retinoic acid-binding protein 1 6.766e-102 0.53
LACB_BOVIN LGB Beta-lactoglobulin 4.875e-97 0.70
LANC2_HUMAN LANCL2 LanC-like protein 2 1.28e-40 0.32
RET4_HUMAN RBP4 Retinol-binding protein 4 2.22e-16 0.71
ABAH3_ARATH CYP707A3 Abscisic acid 8'-hydroxylase 3 4.441e-16 0.31
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 6.162e-14 0.54
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 8.822e-09 0.55

Formoterol

ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.731e-111 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.051e-95 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 4.342e-58 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.401e-57 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.515e-28 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.001997 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.3117 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.6326 1.00
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.447e-78 0.62
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.36e-60 0.41
ADRB3_MOUSE Adrb3 Beta-3 adrenergic receptor 5.227e-54 0.43
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 3.705e-44 0.41
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.254e-41 0.41
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 2.133e-25 0.31
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 1.139e-24 0.33
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 1.139e-24 0.33
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 1.139e-24 0.33
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 1.139e-24 0.33
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 1.139e-24 0.33
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 1.139e-24 0.33
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 1.139e-24 0.33
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 1.139e-24 0.33
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 1.139e-24 0.33
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 1.139e-24 0.33
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 1.139e-24 0.33
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 1.139e-24 0.33
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 1.139e-24 0.33
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 6.968e-24 0.33
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 8.631e-22 0.49
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 3.142e-20 0.33
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 3.122e-19 0.31
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.63e-17 0.33
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.11e-16 0.45
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.11e-16 0.33
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 2.22e-16 0.33
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.551e-16 0.30
Q49PX0_9POXV N1L N1L 8.882e-16 0.29
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 1.554e-15 0.29
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 1.554e-15 0.29
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 1.554e-15 0.29
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 1.554e-15 0.29
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 1.554e-15 0.29
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 1.554e-15 0.29
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 1.554e-15 0.29
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 1.554e-15 0.29
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 1.554e-15 0.29
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 1.554e-15 0.29
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 1.554e-15 0.29
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 1.554e-15 0.29
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 1.554e-15 0.29
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 1.554e-15 0.29
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 1.554e-15 0.29
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 1.554e-15 0.29
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 1.554e-15 0.29
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 1.554e-15 0.29
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 1.554e-15 0.29
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 1.554e-15 0.29
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 1.554e-15 0.29
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 1.554e-15 0.29
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 1.554e-15 0.29
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 1.554e-15 0.29
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 1.554e-15 0.29
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 1.554e-15 0.29
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 1.554e-15 0.29
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 1.554e-15 0.29
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 1.554e-15 0.29
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 1.554e-15 0.29
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 1.554e-15 0.29
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 1.554e-15 0.29
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 1.554e-15 0.29
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 1.554e-15 0.29
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 1.554e-15 0.29
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 1.554e-15 0.29
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 1.554e-15 0.29
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 1.554e-15 0.29
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 1.554e-15 0.29
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 1.554e-15 0.29
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1.554e-15 0.29
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.554e-15 0.29
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 1.554e-15 0.29
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 1.554e-15 0.29
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 1.554e-15 0.29
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 1.554e-15 0.29
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 1.554e-15 0.29
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 1.554e-15 0.29
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.287e-14 0.49
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 4.33e-12 0.29
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.062e-10 0.34
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 3.866e-10 0.29
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 1.449e-09 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.201e-09 0.45
CALM1_HUMAN CALM1 Calmodulin-1 2.572e-08 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.485e-08 0.31
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 7.314e-08 0.33
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 1.016e-07 0.38
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.031e-07 0.29
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.031e-07 0.29
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.103e-07 0.32
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 3.037e-07 0.30
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 4.926e-07 0.32
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.198e-06 0.55
O97467_PLAFA ht1 Hexose transporter 1 2.026e-06 0.48
O61059_LEIME LmGT2 Glucose transporter 2.247e-06 0.48
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 4.742e-06 0.48
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.373e-06 0.32

Cromoglicic_acid

GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.089e-102 1.00
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 1.863e-97 1.00
GPR35_HUMAN GPR35 G-protein coupled receptor 35 7.098e-39 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 4.145e-56 0.37
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 4.722e-46 0.32
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 1.023e-37 0.30
MDHC_PIG MDH1 Malate dehydrogenase, cytoplasmic 2.563e-36 0.30
Q6VVP7_PLAFA Malate dehydrogenase 2.563e-36 0.30
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 8.333e-36 0.28
Q0PJ46_PLAFA LDH Lactate dehydrogenase 3.18e-30 0.30
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 3.645e-30 0.46
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 2.235e-29 0.36
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 6.439e-27 0.31
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 9.327e-27 0.36
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 3.384e-25 0.33
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.305e-24 0.36
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.897e-24 0.36
KMO_PSEFL kmo Kynurenine 3-monooxygenase 9.719e-24 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.059e-23 0.51
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 6.902e-20 0.37
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.11e-16 0.34
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.331e-16 0.34
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 6.661e-16 0.31
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 2.109e-15 0.33
MMP13_BOVIN MMP13 Collagenase 3 8.105e-15 0.30
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 1.132e-14 0.32
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.54e-14 0.33
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.324e-13 0.46
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 3.878e-13 0.30
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.368e-12 0.30
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.017e-10 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.017e-10 0.29
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.089e-10 0.32
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.748e-10 0.33
PA2GF_HUMAN PLA2G2F Group IIF secretory phospholipase A2 7.549e-10 0.31
GALR2_RAT Galr2 Galanin receptor type 2 8.811e-10 0.28
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.421e-09 0.38
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.76e-09 0.30
Q9JLY8_RAT Ccr1 C-C motif chemokine receptor 1 6.225e-09 0.29
ACES_RAT Ache Acetylcholinesterase 6.458e-09 0.35
MCR_HUMAN NR3C2 Mineralocorticoid receptor 6.618e-09 0.34
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 9.028e-09 0.28
DCOR_HUMAN ODC1 Ornithine decarboxylase 3.793e-08 0.30
MAP1_ECOLI map Methionine aminopeptidase 9.666e-08 0.33
PA21B_MOUSE Pla2g1b Phospholipase A2 1.523e-07 0.31
PA2GE_HUMAN PLA2G2E Group IIE secretory phospholipase A2 1.523e-07 0.31
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 3.071e-07 0.31
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 8.227e-07 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.488e-06 0.30
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 3.292e-06 0.31
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.36e-06 0.30
KMO_HUMAN KMO Kynurenine 3-monooxygenase 9.305e-06 0.31

Clobetasol_propionate

GCR_RAT Nr3c1 Glucocorticoid receptor 3.799e-102 1.00
Q690N0_BOVIN PGR Progesterone receptor 2.765e-58 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 4.746e-43 1.00
ANDR_RAT Ar Androgen receptor 5.254e-06 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.2004 1.00
ATTY_RAT Tat Tyrosine aminotransferase 5.266e-180 0.68
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.42e-14 0.51
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.264e-11 0.37
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.221e-10 0.32
GLNA_HUMAN GLUL Glutamine synthetase 3.221e-10 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 1.08e-09 0.71
IL6_HUMAN IL6 Interleukin-6 3.541e-08 0.32

Doxorubicin

S10A4_HUMAN S100A4 Protein S100-A4 6.956e-99 1.00
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 3.545e-55 1.00
1433G_HUMAN YWHAG 14-3-3 protein gamma 4.48e-49 1.00
O40947_HHV8 ORF 73 2.985e-30 1.00
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 4.419e-25 1.00
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.136e-18 1.00
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 4.222e-09 1.00
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 4.062e-07 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.13e-06 1.00
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.828e-06 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 4.104e-05 1.00
Q7ZJM1_9HIV1 pol Integrase 0.0007536 1.00
MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.0152 1.00
A3EZI9_9HEPC NS3 Genome polyprotein 0.0322 1.00
STRP_STRP1 ska Streptokinase A 0.5042 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.7112 1.00
AURKA_HUMAN AURKA Aurora kinase A 0.944 1.00
FANCF_HUMAN FANCF Fanconi anemia group F protein 3.245e-74 0.59
CHIO_HUMAN CHN2 Beta-chimaerin 1.249e-65 0.52
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 8.105e-15 0.28
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 3.761e-09 0.88
VP16_HHV11 Tegument protein VP16 6.051e-06 0.64

Albuterol

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.146e-86 1.00
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 5.019e-94 0.72
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.179e-60 0.46
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 6.007e-52 0.48
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 5.023e-46 0.37
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 5.023e-46 0.37
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 9.011e-45 0.65
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.986e-40 0.45
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.69e-35 0.45
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.152e-31 0.45
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 2.277e-23 0.37
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.482e-21 0.47
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.581e-20 0.45
G3HDX1_CRIGR Alpha-1B adrenergic receptor 5.806e-19 0.36
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.643e-12 0.45
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.601e-11 0.37
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 9.543e-11 0.45
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.443e-08 0.40

Nitrendipine

CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.128e-81 1.00
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 4.214e-65 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 5.724e-13 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.081e-12 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 3.216e-12 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.208e-09 1.00
AA1R_RAT Adora1 Adenosine receptor A1 2.278e-07 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.5879 1.00
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.118e-276 0.85
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 5.597e-227 0.85
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.845e-167 0.70
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 7.204e-103 0.54
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 4.289e-84 0.37
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 3.392e-75 0.41
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.469e-60 0.63
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 2.297e-55 0.69
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 4.757e-55 0.53
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 4.716e-46 0.45
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 5.025e-46 0.77
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.318e-35 0.63
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 4.329e-30 0.33
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.428e-29 0.63
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.574e-28 0.76
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 1.74e-27 0.31
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 3.583e-27 0.53
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 6.129e-26 0.44
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 7.264e-26 0.31
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 2.185e-25 0.31
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.571e-24 0.63
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 1.742e-23 0.31
GLO2_RAT Hagh Hydroxyacylglutathione hydrolase, mitochondrial 3.915e-23 0.28
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 3.725e-22 0.42
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 9.025e-22 0.31
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 1.845e-21 0.31
ACRO_PIG ACR Acrosin 2.241e-21 0.34
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 8.182e-21 0.29
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.058e-20 0.39
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 2.065e-20 0.53
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 3.493e-20 0.81
Q01HZ7_ORYSA OSIGBa0132E09-OSIGBa0108L24.11 Glutamine synthetase 1.608e-19 0.31
TGM2_CAVCU TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.72e-19 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 9.101e-19 0.63
KPCA_MOUSE Prkca Protein kinase C alpha type 1.681e-18 0.33
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 2.778e-18 0.35
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 2.962e-17 0.31
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.11e-16 0.63
GRP3_HUMAN RASGRP3 Ras guanyl-releasing protein 3 2.22e-16 0.31
ACES_HUMAN ACHE Acetylcholinesterase 3.331e-16 0.58
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 8.882e-16 0.35
Q03732_HBV HBcAg Capsid protein 1.665e-15 0.30
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.998e-15 0.29
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.863e-14 0.63
THAS_RAT Tbxas1 Thromboxane-A synthase 5.218e-14 0.38
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 6.684e-14 0.33
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 6.717e-14 0.33
RORA_HUMAN RORA Nuclear receptor ROR-alpha 8.149e-14 0.37
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 8.893e-14 0.34
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 9.17e-14 0.35
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 2.538e-13 0.32
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.302e-12 0.40
TYTR_TRYBB TPR Trypanothione reductase 1.431e-12 0.36
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 3.533e-12 0.33
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 3.751e-12 0.35
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 6.237e-12 0.32
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 9.7e-12 0.29
DYR_STAAW folA Dihydrofolate reductase 3.177e-11 0.33
KMO_RAT Kmo Kynurenine 3-monooxygenase 4.451e-11 0.34
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 1.635e-10 0.31
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 1.647e-10 0.28
NORA_STAAU norA Quinolone resistance protein NorA 2.286e-10 0.38
AROK_HELPY aroK Shikimate kinase 2.795e-10 0.32
PTN5_HUMAN PTPN5 Tyrosine-protein phosphatase non-receptor type 5 3.023e-10 0.30
Q8IL32_PLAF7 Heat shock protein 90, putative 5.863e-10 0.44
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 6.247e-10 0.31
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 8.603e-10 0.34
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.912e-09 0.34
AROQ_STRCO aroQ 3-dehydroquinate dehydratase 2.15e-09 0.29
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 2.433e-09 0.31
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 6.854e-09 0.32
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 8.532e-09 0.35
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 9.772e-09 0.38
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.908e-08 0.40
AROQ_MYCTU aroQ 3-dehydroquinate dehydratase 3.537e-08 0.33
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 4.082e-08 0.44
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 4.21e-08 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 4.992e-08 0.69
DNAB_MYCTU dnaB Replicative DNA helicase 1.005e-07 0.35
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.074e-07 0.40
ACES_ELEEL ache Acetylcholinesterase 1.112e-07 0.58
MRP2_HUMAN ABCC2 Canalicular multispecific organic anion transporter 1 1.227e-07 0.28
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.345e-07 0.34
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.374e-07 0.63
ANDR_HUMAN AR Androgen receptor 1.833e-07 0.76
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.897e-07 0.51
AA3R_RAT Adora3 Adenosine receptor A3 1.925e-07 0.39
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.041e-07 0.30
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.271e-07 0.69
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.35e-07 0.37
GSTM2_HUMAN GSTM2 Glutathione S-transferase Mu 2 2.533e-07 0.29
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 2.853e-07 0.31
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 3.191e-07 0.46
SENP1_HUMAN SENP1 Sentrin-specific protease 1 3.409e-07 0.33
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.1e-07 0.53
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 4.358e-07 0.34
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.905e-07 0.29
WDR5_HUMAN WDR5 WD repeat-containing protein 5 5.208e-07 0.30
Q8ST54_TRYCR HK Phosphotransferase 5.369e-07 0.31
RECA_MYCTU recA Protein RecA 5.77e-07 0.38
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 6.06e-07 0.69
COLA_CLOPE colA Collagenase ColA 1.109e-06 0.31
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 1.123e-06 0.31
EIS_MYCTU eis N-acetyltransferase Eis 1.277e-06 0.29
BGAL_ECOLX lacZ Beta-galactosidase 1.779e-06 0.37
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.839e-06 0.32
PRGR_HUMAN PGR Progesterone receptor 2.381e-06 0.76
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 2.86e-06 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.948e-06 0.34
AGP1_YEAST AGP1 General amino acid permease AGP1 3.186e-06 0.31
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 3.205e-06 0.31
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.587e-06 0.44
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 3.707e-06 0.37
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.819e-06 0.38
LMP1_EBVB9 LMP1 Latent membrane protein 1 3.909e-06 0.29
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.346e-06 0.30
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 4.354e-06 0.32
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 4.368e-06 0.33
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 4.765e-06 0.36
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 4.963e-06 0.31
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 5.555e-06 0.31
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 5.692e-06 0.33
MMP13_MOUSE Mmp13 Collagenase 3 6.573e-06 0.29
H9B8T9_CAPHI CTSB Cathepsin B 6.644e-06 0.35
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 6.844e-06 0.28
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 7.006e-06 0.34
CAH2_BOVIN CA2 Carbonic anhydrase 2 7.387e-06 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 9.208e-06 0.33

Sertraline

Q9WTR4_RAT Slc6a2 Transporter 7.078e-80 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 4.973e-60 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 9.576e-53 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.577e-49 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.737e-43 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 6.454e-41 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0002947 1.00
Q63380_RAT NET Transporter 0.0003039 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.002173 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.006662 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.007417 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.04204 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.06183 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.08091 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.1002 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
MC5R_HUMAN MC5R Melanocortin receptor 5 0.1414 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.4144 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.5554 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.704 1.00
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 1.046e-73 0.39
SC6A4_MACMU SLC6A4 Sodium-dependent serotonin transporter 3.13e-63 0.33
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 9.927e-59 0.39
F1LNR9_RAT Slc6a2 Transporter 2.843e-54 0.31
Q7JHP9_MACMU SLC6A3 Transporter 2.623e-51 0.33
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 3.57e-28 0.32
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 4.226e-09 0.28
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.178e-07 0.28
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.422e-07 0.35

Dopamine

ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 2.714e-79 1.00
AA2BR_RAT Adora2b Adenosine receptor A2b 1.129e-29 1.00
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.71e-20 1.00
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.153e-18 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 4.053e-12 1.00
DRD1_RAT Drd1 D(1A) dopamine receptor 1.706e-09 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.613e-06 1.00
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.207e-06 1.00
DRD4_RAT Drd4 D(4) dopamine receptor 3.343e-05 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 4.328e-05 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 0.0004562 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 0.0004943 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.009094 1.00
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 0.03059 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 0.03386 1.00
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 0.04875 1.00
DRD3_RAT Drd3 D(3) dopamine receptor 0.05768 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.1363 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.4124 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.4405 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.4419 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.9675 1.00
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 1.854e-64 0.33
TAAR5_HUMAN TAAR5 Trace amine-associated receptor 5 1.42e-57 0.46
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 4.065e-55 0.41
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 4.065e-55 0.41
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 1.259e-52 0.42
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 1.259e-52 0.42
TYTR_CRIFA TPR Trypanothione reductase 1.67e-51 0.41
H9TVJ1_CHISP TyR1 8.759e-45 0.56
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 5.166e-42 0.33
TY3H_RAT Th Tyrosine 3-monooxygenase 7.528e-39 0.31
Q39829_SOYBN Lipoxygenase 6.793e-30 0.48
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.369e-29 0.46
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 7.238e-29 0.67
HMGB1_HUMAN HMGB1 High mobility group protein B1 3.516e-24 0.30
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.019e-23 0.37
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.221e-22 0.62
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.239e-21 0.48
PA_I000X PA Polymerase acidic protein 2.199e-19 0.37
TY3H_HUMAN TH Tyrosine 3-monooxygenase 2.322e-19 0.31
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 4.042e-18 0.33
GRPE_ECOLI grpE Protein GrpE 4.879e-18 0.29
SYN1_BOVIN SYN1 Synapsin-1 4.879e-18 0.29
Q7ZJM1_9HIV1 pol Integrase 6.859e-18 0.46
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 9.992e-16 0.34
SYUA_HUMAN SNCA Alpha-synuclein 9.992e-16 0.44
TYRO_MOUSE Tyr Tyrosinase 7.772e-15 0.37
NANA_STREE nanA Sialidase A 1.688e-14 0.43
TTHY_HUMAN TTR Transthyretin 1.943e-14 0.48
TAAR1_RAT Taar1 Trace amine-associated receptor 1 3.686e-14 0.53
1433G_HUMAN YWHAG 14-3-3 protein gamma 4.952e-14 0.52
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.036e-13 0.48
EZRI_HUMAN EZR Ezrin 1.463e-13 0.33
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.071e-13 0.34
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.701e-13 0.29
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 2.111e-12 0.30
Q2PCB5_DICLA ca Carbonic anhydrase 2.492e-12 0.33
IBP3_HUMAN IGFBP3 Insulin-like growth factor-binding protein 3 5.158e-12 0.35
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.056e-11 0.42
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.406e-11 0.36
CAN_CANAL NCE103 Carbonic anhydrase 2.841e-11 0.34
FABI_ECOLI fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 3.616e-11 0.33
DOPO_RAT Dbh Dopamine beta-hydroxylase 7.17e-11 0.37
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 9.933e-11 0.39
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.648e-10 0.42
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.892e-10 0.41
CAH6_HUMAN CA6 Carbonic anhydrase 6 6.58e-10 0.41
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 7.529e-10 0.33
COMT_PIG COMT Catechol O-methyltransferase 9.414e-10 0.31
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.005e-09 0.37
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.347e-09 0.50
TYRO_HUMAN TYR Tyrosinase 1.526e-09 0.33
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 2.121e-09 0.42
DHPR_RAT Qdpr Dihydropteridine reductase 2.44e-09 0.31
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.213e-09 0.31
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 3.598e-09 0.29
Q49PX0_9POXV N1L N1L 4.483e-09 0.32
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 4.493e-09 0.42
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 5.218e-09 0.41
Q8Z9J9_SALTI folA Dihydrofolate reductase 7.474e-09 0.39
DHPR_HUMAN QDPR Dihydropteridine reductase 8.147e-09 0.31
Q9BEG3_BOVIN 5-lipoxygenase 9.794e-09 0.48
FOS_HUMAN FOS Proto-oncogene c-Fos 1.519e-08 0.48
CAN_YEAST NCE103 Carbonic anhydrase 2.253e-08 0.29
C0IX24_STYPI CA2 Carbonic anhydrase 4.751e-08 0.29
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 4.751e-08 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 6.565e-08 0.41
CAH15_MOUSE Ca15 Carbonic anhydrase 15 8.188e-08 0.41
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 8.788e-08 0.48
B2V8E3_SULSY Carbonate dehydratase 9.319e-08 0.29
B5SU02_STYPI CA Alpha carbonic anhydrase 9.319e-08 0.29
Q31FD6_HYDCU Carbonic anhydrase, alpha family 9.319e-08 0.29
POLG_DEN2P Genome polyprotein 9.381e-08 0.33
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 9.481e-08 0.32
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.374e-07 0.48
A6YCJ1_9METZ Astrosclerin-3 2.287e-07 0.29
MIF_HUMAN MIF Macrophage migration inhibitory factor 3.024e-07 0.55
CAH3_BOVIN CA3 Carbonic anhydrase 3 3.814e-07 0.30
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.423e-07 0.39
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 7.646e-07 0.42
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 8.045e-07 0.33
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 9.677e-07 0.48
MEX5_CAEEL mex-5 Zinc finger protein mex-5 9.842e-07 0.48
CYNT_HELPY cynT Carbonic anhydrase 1.007e-06 0.29
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.223e-06 0.41
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.291e-06 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.991e-06 0.41
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 2.292e-06 0.41
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.528e-06 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.607e-06 0.33
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.304e-06 0.41
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.618e-06 0.41
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 6.155e-06 0.45
O49150_SOLTU Lipoxygenase 7.112e-06 0.29
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 7.924e-06 0.48
CAH_METTE Carbonic anhydrase 8.558e-06 0.28

Ketoprofen

S22A7_RAT Slc22a7 Solute carrier family 22 member 7 2.714e-79 1.00
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 5.168e-45 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.285e-42 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.54e-33 1.00
IL8_HUMAN CXCL8 Interleukin-8 3.726e-25 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 2.45e-22 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.341e-19 1.00
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 0.0001184 1.00
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.076e-121 0.38
EST1_RABIT Liver carboxylesterase 1 5.794e-54 0.38
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 5.507e-53 0.47
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.245e-52 0.32
GLI1_HUMAN GLI1 Zinc finger protein GLI1 4.999e-51 0.54
ACE_MOUSE Ace Angiotensin-converting enzyme 2.38e-41 0.33
KYNU_RAT Kynu Kynureninase 2.85e-39 0.31
EST2_HUMAN CES2 Cocaine esterase 1.695e-36 0.40
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 2.111e-36 0.30
ACER2_HUMAN ACER2 Alkaline ceramidase 2 3.875e-36 0.29
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 3.875e-36 0.29
BLAB_BACCE Metallo-beta-lactamase type 2 9.015e-35 0.39
FNTA_YEAST RAM2 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.387e-31 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.516e-30 0.32
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 2.394e-28 0.31
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 8.009e-28 0.34
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 1.803e-27 0.31
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 6.358e-27 0.31
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.439e-25 0.47
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 1.487e-23 0.31
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 4.943e-23 0.47
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 1.204e-22 0.39
EST1_HUMAN CES1 Liver carboxylesterase 1 1.602e-21 0.40
HELD_ECOLI helD DNA helicase IV 3.642e-20 0.39
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.983e-20 0.38
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 1.823e-19 0.31
MANR_PSEPU mdlA Mandelate racemase 9.803e-19 0.30
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 4.879e-18 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 5.233e-18 0.38
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 7.865e-18 0.39
PA_I000X PA Polymerase acidic protein 5.295e-17 0.32
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 5.551e-16 0.31
PPAP_HUMAN ACP3 Prostatic acid phosphatase 7.772e-16 0.31
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.665e-15 0.44
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 6.328e-15 0.28
KYNU_HUMAN KYNU Kynureninase 3.153e-14 0.31
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 3.697e-14 0.33
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.34e-13 0.37
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 2.056e-13 0.36
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.643e-13 0.39
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.71e-13 0.49
NEP_MOUSE Mme Neprilysin 5.338e-13 0.28
BLA2_BACCE blm Metallo-beta-lactamase type 2 6.675e-13 0.39
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.229e-13 0.31
KMO_RAT Kmo Kynurenine 3-monooxygenase 9.082e-13 0.33
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.776e-12 0.38
PDS_SYNE7 pds 15-cis-phytoene desaturase 4.607e-12 0.29
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 7.882e-12 0.37
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 9.7e-12 0.29
T1QYY3_9HIV1 int Integrase 1.92e-11 0.31
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.309e-11 0.69
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 7.049e-11 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 8.01e-11 0.46
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.415e-10 0.28
PPO1_AGABI PPO1 Polyphenol oxidase 1 4.323e-10 0.32
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.776e-10 0.37
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 5.086e-10 0.31
HDAC1_MOUSE Hdac1 Histone deacetylase 1 5.865e-10 0.36
S100B_HUMAN S100B Protein S100-B 6.171e-10 0.29
Q6DMN0_TOXGO CPL Cathepsin L 7.541e-10 0.29
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 8.646e-10 0.35
RHOA_HUMAN RHOA Transforming protein RhoA 1.179e-09 0.30
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 1.322e-09 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.835e-09 0.41
SL9A2_HUMAN SLC9A2 Sodium/hydrogen exchanger 2 1.863e-09 0.30
VE1_HPV11 E1 Replication protein E1 1.972e-09 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.44e-09 0.31
BLAB_AERHY cphA Metallo-beta-lactamase type 2 3.598e-09 0.29
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.63e-09 0.31
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 5.565e-09 0.33
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.036e-08 0.37
ALBU_BOVIN ALB Serum albumin 1.071e-08 0.39
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.189e-08 0.31
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 1.202e-08 0.36
ACES_ANOGA Ace Acetylcholinesterase 1.223e-08 0.31
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 2.206e-08 0.39
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 2.898e-08 0.34
THIO_HUMAN TXN Thioredoxin 2.929e-08 0.29
Q49PX0_9POXV N1L N1L 4.79e-08 0.28
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 4.951e-08 0.28
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 5.56e-08 0.36
PA_I34A1 PA Polymerase acidic protein 7.753e-08 0.32
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 9.381e-08 0.33
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 9.433e-08 0.30
STS_HUMAN STS Steryl-sulfatase 9.732e-08 0.41
CBPB1_PIG CPB1 Carboxypeptidase B 1.264e-07 0.31
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 1.404e-07 0.36
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.198e-07 0.30
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.222e-07 0.31
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.861e-07 0.31
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 2.869e-07 0.28
NR1H4_MOUSE Nr1h4 Bile acid receptor 3.189e-07 0.35
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 4.337e-07 0.47
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 6.783e-07 0.35
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 7.354e-07 0.40
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 8.058e-07 0.29
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 8.227e-07 0.29
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 8.419e-07 0.33
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 9.482e-07 0.31
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 9.822e-07 0.33
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.052e-06 0.37
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 1.171e-06 0.31
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.823e-06 0.30
OXDA_MOUSE Dao D-amino-acid oxidase 2.252e-06 0.30
PRIO_SHEEP PRNP Major prion protein 3.272e-06 0.28
AGP1_YEAST AGP1 General amino acid permease AGP1 3.285e-06 0.30
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 3.575e-06 0.29
LIPS_RAT Lipe Hormone-sensitive lipase 4.197e-06 0.42
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 4.409e-06 0.39
NEP_HUMAN MME Neprilysin 4.517e-06 0.33
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 4.67e-06 0.31
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 5.177e-06 0.31
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 5.7e-06 0.28
AMPN_HUMAN ANPEP Aminopeptidase N 5.799e-06 0.40
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 6.568e-06 0.29
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 7.112e-06 0.29
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 7.873e-06 0.34
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.876e-06 0.30

Fluocinonide

Q690N0_BOVIN PGR Progesterone receptor 5.351e-72 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.614e-36 1.00
ATTY_RAT Tat Tyrosine aminotransferase 1.864e-97 0.36
GCR_RAT Nr3c1 Glucocorticoid receptor 8.522e-81 0.67
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.865e-10 0.60

Etidronic_acid

B1LRJ1_ECOSM traI Type IV secretion-like conjugative transfer relaxase protein TraI 4.448e-70 1.00
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.487e-37 0.36
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 4.395e-28 0.41
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 2.38e-23 0.31
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 1.045e-13 0.35
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.716e-10 0.35
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 2.795e-09 0.31
Q8ST54_TRYCR HK Phosphotransferase 1.02e-07 0.35

Ramelteon

MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.671e-67 1.00
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.272e-62 1.00
MTR1B_CHICK Melatonin receptor type 1B 2.265e-45 0.40
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 4.657e-35 0.55
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.182e-26 0.42
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.014e-25 0.42
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.607e-20 0.42
SL9A5_HUMAN SLC9A5 Sodium/hydrogen exchanger 5 4.43e-14 0.31
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 6.459e-12 0.32
SL9A2_HUMAN SLC9A2 Sodium/hydrogen exchanger 2 8.149e-10 0.31
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 8.491e-09 0.29
E3UJZ5_SPOLI Ecdysone receptor 1.454e-07 0.30

Physostigmine

CHLE_HUMAN BCHE Cholinesterase 6.515e-63 1.00
ACES_HUMAN ACHE Acetylcholinesterase 5.9e-58 1.00
ACES_TETCF ache Acetylcholinesterase 7.652e-23 1.00
ACES_ELEEL ache Acetylcholinesterase 8.192e-07 1.00
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 0.0001488 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.4816 1.00
CHLE_MOUSE Bche Cholinesterase 2.831e-174 0.70
Q9JKC1_RAT Bche Carboxylic ester hydrolase 4.917e-51 0.74
ACES_MOUSE Ache Acetylcholinesterase 1.573e-26 0.70
ACES_RAT Ache Acetylcholinesterase 2.177e-21 0.75
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 2.442e-15 0.29
CHLE_HORSE BCHE Cholinesterase 5.148e-12 0.34
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 7.306e-11 0.29
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 7.306e-11 0.29
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 7.538e-11 0.33
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 1.245e-10 0.33
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.848e-09 0.53
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.201e-07 0.53
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.913e-07 0.53

Glycopyrronium

ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.8e-62 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.07e-45 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.716e-41 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.126e-18 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.331e-16 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.071e-63 0.37
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.081e-57 0.47
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 3.311e-51 0.47
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 8.414e-45 0.36
Q8WMX0_BOVIN Muscarinic receptor M1 9.733e-45 0.34
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.691e-39 0.47
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 3.243e-25 0.43
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 4.214e-22 0.31
ABHDB_HUMAN ABHD11 Protein ABHD11 6.556e-18 0.28
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 9.84e-18 0.34
Q8WSF8_APLCA Soluble acetylcholine receptor 5.75e-13 0.29
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.32e-10 0.47
MEN1_HUMAN MEN1 Menin 1.477e-10 0.32
ACHP_LYMST Acetylcholine-binding protein 2.421e-09 0.30
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.083e-08 0.43
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.929e-06 0.38

Probenecid

S22A8_RAT Slc22a8 Solute carrier family 22 member 8 5.121e-61 1.00
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 6.524e-44 1.00
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.735e-32 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.328e-28 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.892e-28 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.074e-24 1.00
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.774e-19 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.218e-15 1.00
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 5.892e-188 0.67
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.208e-141 0.39
MEP1B_HUMAN MEP1B Meprin A subunit beta 3.882e-81 0.46
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.074e-71 0.39
Q1A7N1_CANLF TRPM8 Transient receptor potential M8 protein 7.466e-62 0.51
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.567e-54 0.44
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 4.183e-42 0.38
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.151e-37 0.37
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 3.097e-35 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 3.719e-35 0.40
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.134e-30 0.56
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.653e-27 0.69
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 3.382e-25 0.37
AL1A1_RAT Aldh1a1 Retinal dehydrogenase 1 5.379e-25 0.31
COLA_CLOPE colA Collagenase ColA 1.153e-24 0.41
Q2PCB5_DICLA ca Carbonic anhydrase 1.166e-23 0.36
DYN2_RAT Dnm2 Dynamin-2 2.847e-23 0.29
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 5.518e-23 0.28
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 2.144e-22 0.39
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.151e-22 0.38
EST1_RABIT Liver carboxylesterase 1 1.134e-21 0.37
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.239e-21 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.367e-21 0.38
VE1_HPV11 E1 Replication protein E1 1.433e-20 0.32
MMP8_HUMAN MMP8 Neutrophil collagenase 1.776e-20 0.43
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 1.779e-20 0.38
LIMK2_HUMAN LIMK2 LIM domain kinase 2 1.267e-19 0.38
O90781_9PLVG HIV-1 protease HIV-1 protease 1.114e-18 0.33
KAT8_HUMAN KAT8 Histone acetyltransferase KAT8 2.375e-18 0.29
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.204e-18 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.035e-17 0.47
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 2.084e-17 0.29
CAH2_BOVIN CA2 Carbonic anhydrase 2 2.505e-17 0.47
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 2.812e-17 0.37
RARG_HUMAN RARG Retinoic acid receptor gamma 1.11e-16 0.37
VCAM1_HUMAN VCAM1 Vascular cell adhesion protein 1 1.11e-16 0.45
RXRB_HUMAN RXRB Retinoic acid receptor RXR-beta 2.22e-16 0.35
RXRG_HUMAN RXRG Retinoic acid receptor RXR-gamma 3.331e-16 0.35
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 4.441e-16 0.35
MMP3_HUMAN MMP3 Stromelysin-1 6.661e-16 0.38
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 6.661e-16 0.43
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 8.882e-16 0.30
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 8.882e-16 0.35
CYNT_HELPY cynT Carbonic anhydrase 4.219e-15 0.47
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 5.107e-15 0.31
Q9JN24_ECOLX def Peptide deformylase 6.772e-15 0.33
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 8.438e-15 0.38
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 3.364e-14 0.32
CAH4_BOVIN CA4 Carbonic anhydrase 4 6.872e-14 0.47
M2_I72A8 M Matrix protein 2 8.826e-14 0.32
MMP2_HUMAN MMP2 72 kDa type IV collagenase 1.235e-13 0.43
MMP1_HUMAN MMP1 Interstitial collagenase 3.763e-13 0.43
RARA_HUMAN RARA Retinoic acid receptor alpha 1.029e-12 0.38
EST2_HUMAN CES2 Cocaine esterase 1.47e-12 0.37
O49150_SOLTU Lipoxygenase 2.937e-12 0.33
MMP12_MOUSE Mmp12 Macrophage metalloelastase 2.95e-12 0.29
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.187e-12 0.37
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 3.31e-12 0.31
NEUR3_HUMAN NEU3 Sialidase-3 5.581e-12 0.30
ECR_BOMMO EcR Ecdysone receptor 8.252e-12 0.33
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.335e-11 0.33
THA_HUMAN THRA Thyroid hormone receptor alpha 2.897e-11 0.40
THB_HUMAN THRB Thyroid hormone receptor beta 3.245e-11 0.40
C0IX24_STYPI CA2 Carbonic anhydrase 1.134e-10 0.47
Q9YQ12_9HIV1 protease Protease 1.242e-10 0.36
B5SU02_STYPI CA Alpha carbonic anhydrase 2.812e-10 0.47
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.495e-10 0.47
MCLN3_HUMAN MCOLN3 Mucolipin-3 8.49e-10 0.56
RORG_HUMAN RORC Nuclear receptor ROR-gamma 1.09e-09 0.39
MMP13_HUMAN MMP13 Collagenase 3 2.187e-09 0.38
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 3.794e-09 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 6.653e-09 0.38
STS_HUMAN STS Steryl-sulfatase 7.773e-09 0.34
CAS1_ARATH CAS1 Cycloartenol synthase 1.176e-08 0.32
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.455e-08 0.37
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.709e-08 0.30
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.736e-08 0.31
ESR1_HUMAN ESR1 Estrogen receptor 2.02e-08 0.45
MMP7_HUMAN MMP7 Matrilysin 2.209e-08 0.38
RARG_MOUSE Rarg Retinoic acid receptor gamma 2.211e-08 0.35
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 2.26e-08 0.31
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 3.279e-08 0.38
EST1_HUMAN CES1 Liver carboxylesterase 1 4.117e-08 0.37
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.649e-08 0.47
RARB_MOUSE Rarb Retinoic acid receptor beta 4.856e-08 0.35
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 5.111e-08 0.30
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.28e-08 0.38
TYTR_TRYBB TPR Trypanothione reductase 5.6e-08 0.41
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 6.367e-08 0.38
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 7.347e-08 0.31
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.443e-07 0.51
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.486e-07 0.45
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.995e-07 0.29
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.856e-07 0.47
RARA_MOUSE Rara Retinoic acid receptor alpha 3.313e-07 0.35
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.904e-07 0.47
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.24e-07 0.33
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.047e-07 0.31
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 6.933e-07 0.47
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 8.227e-07 0.29
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 8.577e-07 0.35
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 1.032e-06 0.38
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.044e-06 0.47
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.058e-06 0.47
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.237e-06 0.37
P53_HUMAN TP53 Cellular tumor antigen p53 1.71e-06 0.38
B2V8E3_SULSY Carbonate dehydratase 1.816e-06 0.47
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.816e-06 0.47
A6YCJ1_9METZ Astrosclerin-3 3.799e-06 0.47
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 4.23e-06 0.30
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 4.519e-06 0.35
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.964e-06 0.35
Q6FTL6_CANGA NCE103 Carbonic anhydrase 5.167e-06 0.47
Q8MWR1_SPOFR USP Ultraspiracle protein 5.552e-06 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 5.552e-06 0.30
EDNRB_PIG EDNRB Endothelin receptor type B 5.881e-06 0.35

Oxybutynin

ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.717e-51 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.953e-51 1.00
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 4.734e-49 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 6.65e-49 1.00
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.338e-48 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 7.308e-47 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 8.109e-22 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.772e-16 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 5.382e-10 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.563e-05 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.006597 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.2601 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.3252 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.5156 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.8821 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9594 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.9887 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.986e-102 0.53
Q8WMX0_BOVIN Muscarinic receptor M1 2.223e-58 0.39
ABHDB_HUMAN ABHD11 Protein ABHD11 4.955e-20 0.32
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 2.22e-16 0.31
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.071e-11 0.29
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 8.247e-11 0.29
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 8.086e-10 0.42
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.594e-08 0.30
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.847e-08 0.31
MEN1_HUMAN MEN1 Menin 8.66e-08 0.31
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 2.676e-06 0.32

Leflunomide

PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.59e-50 1.00
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 1.012e-43 1.00
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.554e-15 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0001305 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.01118 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.6815 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.9383 1.00
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 3.553e-126 0.41
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.556e-112 0.39
APOB_HUMAN APOB Apolipoprotein B-100 4.892e-109 0.37
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 6.311e-93 0.51
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 1.593e-92 0.37
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 9.678e-75 0.44
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 8.533e-68 0.56
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 3.113e-57 0.51
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 2.387e-51 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 6.514e-49 0.52
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 8.516e-47 0.36
RXFP2_HUMAN RXFP2 Relaxin receptor 2 3.2e-43 0.40
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.482e-42 0.52
S20A2_HUMAN SLC20A2 Sodium-dependent phosphate transporter 2 8.37e-41 0.32
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 1.845e-39 0.34
STIM2_HUMAN STIM2 Stromal interaction molecule 2 2.83e-38 0.30
SRPK1_MOUSE Srpk1 SRSF protein kinase 1 6.694e-38 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.657e-35 0.36
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 4.514e-34 0.29
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 1.471e-32 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.044e-32 0.49
PTGES_CANLF PTGES Prostaglandin E synthase 1.396e-31 0.31
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 7.146e-31 0.46
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.091e-30 0.52
EHMT2_MOUSE Ehmt2 Histone-lysine N-methyltransferase EHMT2 1.955e-30 0.38
SHH_MOUSE Shh Sonic hedgehog protein 4.693e-30 0.38
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 9.904e-29 0.46
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 1.33e-27 0.34
Q25615_ONCVO Chitinase 1.361e-27 0.33
S20A1_HUMAN SLC20A1 Sodium-dependent phosphate transporter 1 3.081e-26 0.32
JUN_HUMAN JUN Transcription factor AP-1 4.941e-26 0.42
PSBA_MARPO psbA Photosystem II protein D1 1.952e-25 0.50
PTGES_HUMAN PTGES Prostaglandin E synthase 7.305e-25 0.42
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 4.908e-24 0.40
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 8.894e-24 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.122e-23 0.49
SMO_MOUSE Smo Smoothened homolog 2.205e-23 0.37
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.911e-22 0.36
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 8.909e-22 0.44
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 3.379e-21 0.34
PSBA_SPIOL psbA Photosystem II protein D1 3.608e-21 0.50
LCK_HUMAN LCK Tyrosine-protein kinase Lck 6.125e-21 0.42
TIE2_HUMAN TEK Angiopoietin-1 receptor 8.448e-21 0.36
SORT_HUMAN SORT1 Sortilin 2.532e-20 0.38
LIPL_HUMAN LPL Lipoprotein lipase 6.697e-20 0.32
ACRO_HUMAN ACR Acrosin 8.345e-20 0.35
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.784e-19 0.46
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 7.04e-19 0.35
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.374e-18 0.52
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 3.66e-18 0.32
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 5.442e-18 0.35
SMO_HUMAN SMO Smoothened homolog 7.12e-18 0.37
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 7.856e-18 0.45
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 9.058e-18 0.35
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 1.152e-17 0.35
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.469e-17 0.52
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.562e-17 0.38
PRIO_SHEEP PRNP Major prion protein 1.828e-17 0.30
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.11e-16 0.38
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 9.992e-16 0.38
HDAC4_HUMAN HDAC4 Histone deacetylase 4 1.11e-15 0.38
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 2.109e-15 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 3.109e-15 0.38
ANO1_HUMAN ANO1 Anoctamin-1 3.775e-15 0.36
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.33e-15 0.41
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 5.107e-15 0.38
BLK_HUMAN BLK Tyrosine-protein kinase Blk 5.329e-15 0.34
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.377e-14 0.35
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.821e-14 0.37
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.165e-14 0.32
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.165e-14 0.32
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 3.164e-14 0.33
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 7.602e-13 0.31
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.883e-12 0.46
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 6.418e-12 0.43
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.505e-12 0.42
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.062e-11 0.38
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.332e-11 0.32
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 2.4e-11 0.43
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 2.533e-11 0.29
FA12_HUMAN F12 Coagulation factor XII 3.443e-11 0.32
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 3.897e-11 0.38
DPEP1_HUMAN DPEP1 Dipeptidase 1 6.626e-11 0.29
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 8.191e-11 0.37
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 8.223e-11 0.34
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.076e-10 0.36
ELOV6_MOUSE Elovl6 Elongation of very long chain fatty acids protein 6 2.131e-10 0.30
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 4.894e-10 0.52
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 5.051e-10 0.32
TRPC3_HUMAN TRPC3 Short transient receptor potential channel 3 6.99e-10 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 7.272e-10 0.36
PYRD_PLAF7 Dihydroorotate dehydrogenase (quinone), mitochondrial 1.087e-09 0.29
ELOV3_HUMAN ELOVL3 Elongation of very long chain fatty acids protein 3 1.117e-09 0.30
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.162e-09 0.33
TPA_HUMAN PLAT Tissue-type plasminogen activator 1.185e-09 0.34
AURKA_HUMAN AURKA Aurora kinase A 1.543e-09 0.41
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 1.646e-09 0.32
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 2.596e-09 0.39
BACE2_RAT Bace2 Beta-secretase 2 3.598e-09 0.29
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 3.779e-09 0.34
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.854e-09 0.34
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 5.415e-09 0.31
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 6.379e-09 0.39
BTK_HUMAN BTK Tyrosine-protein kinase BTK 9.341e-09 0.41
PANC_MYCTU panC Pantothenate synthetase 1.031e-08 0.33
ECR_AEDAE EcR Ecdysone receptor 1.594e-08 0.30
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 1.606e-08 0.40
AURKB_HUMAN AURKB Aurora kinase B 1.685e-08 0.43
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 2.079e-08 0.34
TEC_HUMAN TEC Tyrosine-protein kinase Tec 2.257e-08 0.34
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.269e-08 0.31
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 2.337e-08 0.32
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 2.638e-08 0.31
TYSY_ECOLI thyA Thymidylate synthase 3.456e-08 0.38
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 4.699e-08 0.32
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 5.476e-08 0.32
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 5.536e-08 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 5.544e-08 0.36
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 6.378e-08 0.30
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 6.536e-08 0.32
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 6.571e-08 0.32
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 8.238e-08 0.29
BACE2_HUMAN BACE2 Beta-secretase 2 9.764e-08 0.33
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 1.132e-07 0.31
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.172e-07 0.52
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.191e-07 0.32
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.323e-07 0.38
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.49e-07 0.32
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.514e-07 0.32
TRAR_RHIRD traR Transcriptional activator protein TraR 1.747e-07 0.28
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.868e-07 0.32
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 3.273e-07 0.32
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.311e-07 0.44
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.513e-07 0.29
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.642e-07 0.31
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 4.595e-07 0.32
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 5.651e-07 0.31
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 6.337e-07 0.30
BACE1_HUMAN BACE1 Beta-secretase 1 6.895e-07 0.37
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 7.681e-07 0.32
EST2_HUMAN CES2 Cocaine esterase 7.784e-07 0.35
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 8.055e-07 0.48
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 8.463e-07 0.31
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 8.525e-07 0.30
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 9.396e-07 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 9.434e-07 0.31
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.061e-06 0.32
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.263e-06 0.32
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1.382e-06 0.32
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.397e-06 0.39
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.552e-06 0.31
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.599e-06 0.33
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 1.641e-06 0.31
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.732e-06 0.30
XBP1_HUMAN XBP1 X-box-binding protein 1 2.111e-06 0.40
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.415e-06 0.39
Q8MWR1_SPOFR USP Ultraspiracle protein 2.536e-06 0.32
Q8MWR2_SPOFR EcR Ecdysteroid receptor 2.536e-06 0.32
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 2.554e-06 0.29
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.849e-06 0.29
SCAF_HCMVA UL80 Capsid scaffolding protein 2.969e-06 0.33
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 3.098e-06 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.272e-06 0.28
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 3.3e-06 0.32
TXK_HUMAN TXK Tyrosine-protein kinase TXK 3.445e-06 0.34
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 4.354e-06 0.32
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.857e-06 0.35
LUCI_AQULA Luciferin 4-monooxygenase 5.02e-06 0.29
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 5.212e-06 0.34
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 5.885e-06 0.32
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 6.195e-06 0.32
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 6.294e-06 0.33
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 6.433e-06 0.29
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 6.83e-06 0.48
FER_HUMAN FER Tyrosine-protein kinase Fer 6.89e-06 0.29
V2R_RAT Avpr2 Vasopressin V2 receptor 7.345e-06 0.31
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 8.465e-06 0.34
KC1G3_HUMAN CSNK1G3 Casein kinase I isoform gamma-3 9.092e-06 0.30
IL2_HUMAN IL2 Interleukin-2 9.348e-06 0.30
UROK_HUMAN PLAU Urokinase-type plasminogen activator 9.956e-06 0.40

Emedastine

HRH1_CAVPO HRH1 Histamine H1 receptor 2.348e-48 1.00
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 4.348e-71 0.38
HMOX2_RAT Hmox2 Heme oxygenase 2 9.74e-66 0.35
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.325e-65 0.38
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 4.107e-56 0.32
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 1.958e-41 0.41
HRH4_HUMAN HRH4 Histamine H4 receptor 6.429e-28 0.43
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 4.267e-26 0.52
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 6.757e-23 0.37
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 5.223e-20 0.38
SOS1_HUMAN SOS1 Son of sevenless homolog 1 1.193e-19 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 2.455e-18 0.62
RENI_MACMU REN Renin 7.773e-18 0.28
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.174e-17 0.45
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 8.737e-14 0.36
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.606e-12 0.31
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.484e-12 0.43
CHKA_HUMAN CHKA Choline kinase alpha 4.487e-12 0.31
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.582e-12 0.52
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 8.356e-12 0.29
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 5.341e-10 0.32
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.4e-09 0.32
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 2.217e-09 0.36
HRH4_RAT Hrh4 Histamine H4 receptor 3.582e-09 0.30
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.518e-08 0.30
O97467_PLAFA ht1 Hexose transporter 1 7.386e-08 0.34
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.42e-07 0.43
HRH2_HUMAN HRH2 Histamine H2 receptor 2.458e-07 0.30
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 2.614e-07 0.37
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.078e-07 0.34
O61059_LEIME LmGT2 Glucose transporter 4.596e-07 0.34
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.297e-06 0.52
PRIO_MESAU PRNP Major prion protein 2.185e-06 0.29
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.64e-06 0.34

Ibuprofen

S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.446e-45 1.00
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 6.524e-44 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.065e-38 1.00
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.735e-32 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.076e-32 1.00
IL8_HUMAN CXCL8 Interleukin-8 3.184e-24 1.00
ALBU_BOVIN ALB Serum albumin 6.843e-21 1.00
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 4.197e-20 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.11e-16 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 2.22e-16 1.00
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 2.387e-14 1.00
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 2.662e-06 1.00
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 0.000121 1.00
CBPA1_HUMAN CPA1 Carboxypeptidase A1 7.528e-93 0.36
NEP_RABIT MME Neprilysin 2.649e-85 0.38
NEP_MOUSE Mme Neprilysin 2.35e-77 0.38
NEP_HUMAN MME Neprilysin 2.361e-75 0.38
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 2.905e-72 0.40
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 4.531e-67 0.38
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.353e-63 0.37
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 4.188e-60 0.45
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.078e-59 0.50
NEP_RAT Mme Neprilysin 5.989e-58 0.41
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 3.105e-52 0.29
ACE_MOUSE Ace Angiotensin-converting enzyme 1.194e-49 0.34
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.009e-49 0.35
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.828e-48 0.37
AMPB_MOUSE Rnpep Aminopeptidase B 1.697e-47 0.38
AMPL_BOVIN LAP3 Cytosol aminopeptidase 1.697e-47 0.38
AMPB_RAT Rnpep Aminopeptidase B 4.268e-47 0.38
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 5.665e-42 0.35
AMPN_PIG ANPEP Aminopeptidase N 1.008e-40 0.38
NEP_PIG MME Neprilysin 6.619e-40 0.35
TY3H_RAT Th Tyrosine 3-monooxygenase 4.474e-39 0.31
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 8.864e-38 0.33
ACE_HUMAN ACE Angiotensin-converting enzyme 7.636e-37 0.38
Q99P97_RAT Histone deacetylase 6 3.875e-36 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.013e-36 0.35
MURI_LACFE murI Glutamate racemase 9.362e-36 0.28
AMPB_HUMAN RNPEP Aminopeptidase B 1.117e-35 0.37
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.396e-35 0.36
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 4.974e-33 0.35
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 8.015e-32 0.39
AMP1_PLAFQ M1 family aminopeptidase 5.804e-28 0.38
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 2.449e-27 0.33
BLAB_BACCE Metallo-beta-lactamase type 2 6.161e-27 0.30
MMP8_RAT Mmp8 Neutrophil collagenase 1.61e-26 0.30
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.318e-24 0.40
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 1.409e-23 0.38
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 1.479e-23 0.34
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.431e-23 0.46
HDAC1_RAT Hdac1 Histone deacetylase 1 1.111e-22 0.29
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.5e-20 0.36
ACE_RAT Ace Angiotensin-converting enzyme 8.171e-20 0.37
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.193e-19 0.31
DPP2_RAT Dpp7 Dipeptidyl peptidase 2 1.225e-19 0.31
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 1.481e-19 0.30
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.551e-19 0.38
TY3H_HUMAN TH Tyrosine 3-monooxygenase 1.802e-19 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 2.653e-19 0.38
Q39829_SOYBN Lipoxygenase 3.122e-19 0.31
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.753e-18 0.29
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 4.879e-18 0.29
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 6.298e-18 0.46
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 6.791e-18 0.29
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.262e-17 0.29
HELD_ECOLI helD DNA helicase IV 4.11e-17 0.33
NK1R_RAT Tacr1 Substance-P receptor 2.22e-16 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 8.882e-16 0.64
AMPX_VIBPR Bacterial leucyl aminopeptidase 2.887e-15 0.38
MDM4_HUMAN MDM4 Protein Mdm4 3.553e-15 0.33
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 3.664e-15 0.30
CSK_HUMAN CSK Tyrosine-protein kinase CSK 6.217e-15 0.41
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 4.641e-14 0.36
AMPN_MOUSE Anpep Aminopeptidase N 7.239e-14 0.38
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 7.55e-14 0.30
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 1.372e-13 0.30
BLA2_BACCE blm Metallo-beta-lactamase type 2 4.522e-13 0.38
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 4.773e-13 0.40
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 6.587e-13 0.32
ACE_RABIT ACE Angiotensin-converting enzyme 7.325e-13 0.36
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 7.834e-13 0.31
THER_BACTH npr Thermolysin 2.446e-12 0.38
MMP9_RAT Mmp9 Matrix metalloproteinase-9 1.1e-11 0.30
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 3.646e-11 0.29
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 5.513e-11 0.30
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 9.768e-11 0.31
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 2.659e-10 0.30
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 5.02e-10 0.33
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.019e-09 0.33
CBPB1_HUMAN CPB1 Carboxypeptidase B 1.124e-09 0.36
CBPB2_HUMAN CPB2 Carboxypeptidase B2 1.628e-09 0.37
ANF_HUMAN NPPA Natriuretic peptides A 2.37e-09 0.33
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 2.852e-09 0.37
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.641e-09 0.38
MMP8_HUMAN MMP8 Neutrophil collagenase 1.116e-08 0.33
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.344e-08 0.58
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.082e-08 0.31
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 3.377e-08 0.29
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 4.248e-08 0.33
GLI1_HUMAN GLI1 Zinc finger protein GLI1 4.675e-08 0.28
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 8.205e-08 0.32
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 8.23e-08 0.31
ESR2_RAT Esr2 Estrogen receptor beta 1.56e-07 0.32
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.746e-07 0.31
CBPB1_PIG CPB1 Carboxypeptidase B 3.447e-07 0.29
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 3.995e-07 0.31
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 4.173e-07 0.42
ECE1_RAT Ece1 Endothelin-converting enzyme 1 4.485e-07 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 6.122e-07 0.48
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 6.707e-07 0.29
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 7.208e-07 0.30
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 9.746e-07 0.33
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 1.213e-06 0.33
Q72874_9HIV1 pol Pol polyprotein 1.279e-06 0.34
NR1H4_MOUSE Nr1h4 Bile acid receptor 1.544e-06 0.31
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.692e-06 0.33
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.877e-06 0.49
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.185e-06 0.29
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 2.218e-06 0.33
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.91e-06 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.851e-06 0.38
MMP2_HUMAN MMP2 72 kDa type IV collagenase 5.093e-06 0.38
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 5.724e-06 0.33
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 8.279e-06 0.28

Rivastigmine

Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 8.717e-45 1.00
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.199e-18 1.00
CHLE_HORSE BCHE Cholinesterase 2.661e-11 1.00
ACES_BOVIN ACHE Acetylcholinesterase 1.422e-10 1.00
CHLE_MOUSE Bche Cholinesterase 1.679e-09 1.00
ACES_RAT Ache Acetylcholinesterase 1.377e-08 1.00
ACES_MOUSE Ache Acetylcholinesterase 0.0005085 1.00
PA2A1_NAJMO Acidic phospholipase A2 CM-I 1.102e-37 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.835e-31 0.31
PDS_SYNE7 pds 15-cis-phytoene desaturase 4.752e-26 0.35
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 6.106e-15 0.28
ACES_HUMAN ACHE Acetylcholinesterase 3.908e-14 0.74
CHLE_HUMAN BCHE Cholinesterase 6.761e-14 0.66
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 3.365e-13 0.54
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.199e-12 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.888e-12 0.40
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.097e-11 0.34
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.447e-11 0.54
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.878e-11 0.29
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 1.369e-10 0.28
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 1.369e-10 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.474e-09 0.34
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 3.825e-09 0.33
AOC3_HUMAN AOC3 Membrane primary amine oxidase 4.478e-08 0.37
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 3.222e-07 0.34
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.42e-06 0.32
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.53e-06 0.30
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 3.909e-06 0.31
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.084e-06 0.32

Procainamide

S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 6.524e-44 1.00
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.123e-34 1.00
ACES_BOVIN ACHE Acetylcholinesterase 0.005207 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.007228 1.00
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 7.414e-66 0.43
CBX8_HUMAN CBX8 Chromobox protein homolog 8 3.441e-56 0.31
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 3.068e-53 0.31
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 6.753e-45 0.31
ECR_CHITE EcR Ecdysone receptor 5.166e-42 0.33
ECR_HELVI EcR Ecdysone receptor 5.166e-42 0.33
O45117_CHITE USP-1 Ultraspiracle 5.166e-42 0.33
Q6IVK1_PLOIN USP 5.166e-42 0.33
Q6RVD3_PLOIN Ecdysone receptor 5.166e-42 0.33
Q7SIF6_HELVI Gene regulation protein 5.166e-42 0.33
Q8I1M8_CHISP CsUSP Ultraspiracle 5.166e-42 0.33
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 5.166e-42 0.33
Q962I5_LUCCU Ultraspiracle protein 5.166e-42 0.33
USP_CHOFU USP Protein ultraspiracle homolog 5.166e-42 0.33
CBX7_HUMAN CBX7 Chromobox protein homolog 7 5.259e-39 0.31
CBX5_HUMAN CBX5 Chromobox protein homolog 5 7.142e-37 0.29
CBX2_HUMAN CBX2 Chromobox protein homolog 2 1.332e-36 0.29
CBX6_HUMAN CBX6 Chromobox protein homolog 6 1.332e-36 0.29
CDY1_HUMAN CDY1; CDY1B Testis-specific chromodomain protein Y 1 1.332e-36 0.29
CDYL_HUMAN CDYL Chromodomain Y-like protein 1.332e-36 0.29
COMT_PIG COMT Catechol O-methyltransferase 7.88e-31 0.36
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 4.433e-30 0.47
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.736e-28 0.52
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.793e-27 0.33
HDAC6_HUMAN HDAC6 Histone deacetylase 6 5.007e-27 0.52
Q8WMX0_BOVIN Muscarinic receptor M1 6.226e-27 0.35
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 4.811e-26 0.59
ECR_BOMMO EcR Ecdysone receptor 6.605e-26 0.34
USP_DROME usp Protein ultraspiracle 1.178e-25 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.238e-25 0.36
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 2.987e-23 0.33
E3UJZ5_SPOLI Ecdysone receptor 2.791e-22 0.33
PRP4_HUMAN PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 1.571e-21 0.34
ECR_DROME EcR Ecdysone receptor 4.749e-21 0.33
Q4W6C8_LEPDE LdUSP Ultraspiracle 6.654e-21 0.33
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 6.654e-21 0.33
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 9.092e-21 0.33
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 8.065e-20 0.38
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 8.068e-20 0.53
CLPP_STAA8 clpP ATP-dependent Clp protease proteolytic subunit 9.056e-18 0.28
Q9GSG8_AEDAE Ultraspiracle isoform-A 1.882e-17 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.547e-17 0.51
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.11e-16 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.11e-16 0.48
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.11e-16 0.68
NR1H4_HUMAN NR1H4 Bile acid receptor 2.22e-16 0.39
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 3.331e-16 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.331e-16 0.33
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 1.221e-15 0.34
STK3_MOUSE Stk3 Serine/threonine-protein kinase 3 1.221e-15 0.34
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.443e-15 0.52
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 2.998e-15 0.34
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 3.997e-15 0.42
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.216e-15 0.50
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 1.699e-14 0.39
DRD1_PIG DRD1 D(1A) dopamine receptor 2.265e-14 0.45
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.52e-14 0.35
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.787e-14 0.39
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 5.851e-14 0.34
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 6.928e-14 0.36
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.055e-13 0.51
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 8.378e-13 0.33
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 1.51e-12 0.34
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.512e-12 0.32
HDAC4_HUMAN HDAC4 Histone deacetylase 4 2.659e-12 0.52
THAS_RAT Tbxas1 Thromboxane-A synthase 3.805e-12 0.33
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 4.114e-12 0.30
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.184e-12 0.60
ERG2_YEAST ERG2 C-8 sterol isomerase 1.149e-11 0.33
DPO1_THEAQ polA DNA polymerase I, thermostable 1.308e-11 0.31
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.884e-11 0.58
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 3.66e-11 0.35
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.805e-11 0.60
CAH2_BOVIN CA2 Carbonic anhydrase 2 3.979e-11 0.34
H9B8T9_CAPHI CTSB Cathepsin B 5.418e-11 0.34
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 7.128e-11 0.34
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 7.128e-11 0.34
Q8MWR1_SPOFR USP Ultraspiracle protein 7.356e-11 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 7.356e-11 0.30
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.05e-10 0.33
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 1.105e-10 0.29
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 1.182e-10 0.31
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.229e-10 0.50
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.314e-10 0.40
ECR_LUCCU EcR Ecdysone receptor 1.441e-10 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.69e-10 0.43
ACES_MOUSE Ache Acetylcholinesterase 1.957e-10 0.35
GLUC_HUMAN GCG Glucagon 2.065e-10 0.30
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.351e-10 0.33
GPR4_MOUSE Gpr4 G-protein coupled receptor 4 3.34e-10 0.30
DLK1_HUMAN DLK1 Protein delta homolog 1 3.399e-10 0.34
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 3.399e-10 0.34
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 3.622e-10 0.37
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 4.715e-10 0.32
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 5.67e-10 0.33
TERT_HUMAN TERT Telomerase reverse transcriptase 8.151e-10 0.39
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 1.08e-09 0.38
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 1.278e-09 0.34
GPR4_RAT Gpr4 G-protein coupled receptor 4 1.692e-09 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.952e-09 0.29
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.947e-09 0.41
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 3.086e-09 0.34
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 3.536e-09 0.34
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 4e-09 0.34
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 4e-09 0.34
MYO3A_HUMAN MYO3A Myosin-IIIa 4e-09 0.34
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 4e-09 0.34
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 4e-09 0.34
NDKB_HUMAN NME2 Nucleoside diphosphate kinase B 6.78e-09 0.30
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 6.78e-09 0.30
HDAC9_HUMAN HDAC9 Histone deacetylase 9 1.012e-08 0.33
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 1.081e-08 0.34
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.081e-08 0.34
MYO3B_HUMAN MYO3B Myosin-IIIb 1.081e-08 0.34
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.107e-08 0.34
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 2.415e-08 0.35
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 2.599e-08 0.34
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 2.599e-08 0.34
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 2.599e-08 0.34
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 2.599e-08 0.34
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 2.599e-08 0.34
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.04e-08 0.47
VDR_HUMAN VDR Vitamin D3 receptor 3.58e-08 0.37
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.776e-08 0.47
STXA_SHIDY stxA Shiga toxin subunit A 3.985e-08 0.29
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 5.667e-08 0.34
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 5.667e-08 0.34
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 5.667e-08 0.34
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 5.886e-08 0.35
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 6.413e-08 0.30
CYNT_HELPY cynT Carbonic anhydrase 7.908e-08 0.36
HDAC2_HUMAN HDAC2 Histone deacetylase 2 8.949e-08 0.38
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 9.79e-08 0.37
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 1.14e-07 0.34
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 1.14e-07 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.142e-07 0.44
HDAC1_RAT Hdac1 Histone deacetylase 1 1.379e-07 0.37
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.512e-07 0.56
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.755e-07 0.38
O77240_CHOFU EcR Ecdysone receptor isoform A 1.848e-07 0.33
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 2.142e-07 0.34
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 2.142e-07 0.34
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.142e-07 0.34
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 2.142e-07 0.34
PRIO_SHEEP PRNP Major prion protein 2.485e-07 0.34
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 3.205e-07 0.29
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.445e-07 0.36
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 3.8e-07 0.34
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 3.8e-07 0.34
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.8e-07 0.34
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.847e-07 0.34
KLF5_HUMAN KLF5 Krueppel-like factor 5 4.157e-07 0.31
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 5.227e-07 0.32
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 5.445e-07 0.35
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.467e-07 0.37
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 6.072e-07 0.31
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 6.412e-07 0.34
INSRR_HUMAN INSRR Insulin receptor-related protein 6.412e-07 0.34
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 6.412e-07 0.34
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 6.412e-07 0.34
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 6.412e-07 0.34
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 6.83e-07 0.37
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 7.161e-07 0.38
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.036e-06 0.34
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.036e-06 0.34
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 1.036e-06 0.34
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 1.036e-06 0.34
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 1.036e-06 0.34
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.093e-06 0.37
CAH4_BOVIN CA4 Carbonic anhydrase 4 1.265e-06 0.50
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.401e-06 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.489e-06 0.36
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.504e-06 0.29
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.613e-06 0.34
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.613e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 1.716e-06 0.32
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.044e-06 0.32
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.297e-06 0.47
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.429e-06 0.34
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 2.429e-06 0.34
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 2.429e-06 0.34
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 2.429e-06 0.34
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.429e-06 0.34
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.878e-06 0.45
DRD4_RAT Drd4 D(4) dopamine receptor 3.086e-06 0.33
GALR1_HUMAN GALR1 Galanin receptor type 1 3.144e-06 0.35
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 3.469e-06 0.30
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 3.553e-06 0.34
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 3.553e-06 0.34
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 3.553e-06 0.34
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 3.553e-06 0.34
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.062e-06 0.34
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 5.062e-06 0.34
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 5.062e-06 0.34
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 5.062e-06 0.34
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 5.062e-06 0.34
CATG_HUMAN CTSG Cathepsin G 6.078e-06 0.35
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 6.14e-06 0.34
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 7.048e-06 0.34
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 7.048e-06 0.34
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 7.896e-06 0.29
PLD1_RAT Pld1 Phospholipase D1 8.558e-06 0.28
PI2R_HUMAN PTGIR Prostacyclin receptor 9.081e-06 0.38
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 9.61e-06 0.34
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 9.61e-06 0.34
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 9.61e-06 0.34

Selegiline

AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.666e-40 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.441e-16 1.00
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 5.337e-11 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.1002 1.00
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 3.855e-54 0.30
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 7.539e-41 0.42
NEP_MOUSE Mme Neprilysin 2.249e-39 0.31
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 4.094e-35 0.68
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.719e-31 0.33
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 2.535e-29 0.29
AMPB_RAT Rnpep Aminopeptidase B 1.191e-26 0.31
AMPB_HUMAN RNPEP Aminopeptidase B 9.044e-21 0.29
Q39829_SOYBN Lipoxygenase 8.104e-18 0.28
NEP_RABIT MME Neprilysin 1.064e-17 0.33
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 5.234e-17 0.74
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.22e-16 0.31
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 4.441e-16 0.40
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.01e-14 0.30
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 2.601e-12 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.292e-12 0.59
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.715e-10 0.40
DRD2_CHLAE DRD2 D(2) dopamine receptor 5.481e-10 0.30
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 6.74e-10 0.56
MMP8_RAT Mmp8 Neutrophil collagenase 4.316e-09 0.28
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.322e-08 0.29
CATL1_BOVIN CTSL Cathepsin L1 1.536e-08 0.29
Q49PX0_9POXV N1L N1L 2.006e-08 0.30
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.181e-08 0.30
PAPA1_CARPA Papain 4.531e-08 0.30
AOC3_HUMAN AOC3 Membrane primary amine oxidase 8.119e-08 0.34
NEP_RAT Mme Neprilysin 1.088e-07 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 1.221e-07 0.29
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.278e-07 0.33
ACE_MOUSE Ace Angiotensin-converting enzyme 4.905e-07 0.29
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 9.493e-07 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.479e-06 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 2.044e-06 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.185e-06 0.29

Letrozole

CP19A_HUMAN CYP19A1 Aromatase 3.912e-40 1.00
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 9.782e-11 1.00
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 6.6e-09 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.7785 1.00
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 3.042e-41 0.31
CP19A_RAT Cyp19a1 Aromatase 2.015e-33 0.66
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 1.605e-25 0.55
PGTB1_HUMAN PGGT1B Geranylgeranyl transferase type-1 subunit beta 7.55e-15 0.33
EGLN2_HUMAN EGLN2 Egl nine homolog 2 1.263e-11 0.35
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 1.189e-08 0.31
MGLL_RAT Mgll Monoglyceride lipase 1.377e-07 0.32
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 1.41e-07 0.31
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 4.858e-07 0.31
STS_HUMAN STS Steryl-sulfatase 6.431e-07 0.57
GRIA3_HUMAN GRIA3 Glutamate receptor 3 7.045e-07 0.29
MGLL_MOUSE Mgll Monoglyceride lipase 3.01e-06 0.32
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 3.572e-06 0.30
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.495e-06 0.33
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 7.884e-06 0.31
C11B2_MOUSE Cyp11b2 Cytochrome P450 11B2, mitochondrial 7.884e-06 0.31
FNTA_MOUSE Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 8.8e-06 0.32
FNTB_MOUSE Fntb Protein farnesyltransferase subunit beta 8.8e-06 0.32

Glyburide

ABCBB_RAT Abcb11 Bile salt export pump 4.629e-39 1.00
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 3.416e-35 1.00
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 3.59e-28 1.00
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.419e-25 1.00
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 4.222e-09 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 3.915e-06 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.079e-05 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.42e-05 1.00
ABCC9_HUMAN ABCC9 ATP-binding cassette sub-family C member 9 1.449e-05 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0001176 1.00
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 0.000323 1.00
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 2.448e-93 0.69
TA2R_MOUSE Tbxa2r Thromboxane A2 receptor 6.743e-82 0.32
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 1.993e-76 0.51
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 7.227e-75 0.55
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.96e-71 0.35
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.219e-56 0.35
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.983e-54 0.55
DRD2_CANLF DRD2 D(2) dopamine receptor 2.433e-48 0.38
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 3.727e-40 0.32
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 7.304e-40 0.36
CNR1_HUMAN CNR1 Cannabinoid receptor 1 1.233e-37 0.38
SCNNA_MOUSE Scnn1a Amiloride-sensitive sodium channel subunit alpha 1.833e-36 0.31
TA2R_RAT Tbxa2r Thromboxane A2 receptor 1.137e-34 0.38
PSBA_SPIOL psbA Photosystem II protein D1 1.737e-34 0.32
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 6.287e-32 0.35
CRFR2_HUMAN CRHR2 Corticotropin-releasing factor receptor 2 6.018e-31 0.29
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 1.282e-30 0.43
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.849e-30 0.34
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 1.52e-28 0.35
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 2.134e-27 0.35
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 2.688e-27 0.35
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.03e-26 0.36
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.686e-26 0.41
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 2.093e-26 0.35
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.017e-25 0.40
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 4.804e-24 0.39
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 5.78e-24 0.42
MSHB_MYCTU mshB 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 6.794e-23 0.28
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.234e-22 0.43
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 7.333e-21 0.35
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.673e-20 0.42
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 2.494e-20 0.39
MIP_LEGPN mip Outer membrane protein MIP 5.434e-20 0.32
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 3.485e-19 0.38
DRD1_BOVIN DRD1 D(1A) dopamine receptor 6.844e-19 0.35
DRD3_RAT Drd3 D(3) dopamine receptor 9.307e-19 0.34
DRD2_RAT Drd2 D(2) dopamine receptor 2.225e-18 0.42
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 3.803e-18 0.41
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 4.879e-18 0.29
UHRF1_HUMAN UHRF1 E3 ubiquitin-protein ligase UHRF1 6.229e-18 0.28
DPOL_HHV6U U38 DNA polymerase catalytic subunit 6.934e-18 0.37
LYAM3_HUMAN SELP P-selectin 2.799e-17 0.32
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 3.323e-17 0.37
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 3.444e-17 0.34
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.11e-16 0.38
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 2.22e-16 0.30
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 3.331e-16 0.34
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 7.772e-16 0.33
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.109e-15 0.38
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 7.327e-15 0.36
SYUA_HUMAN SNCA Alpha-synuclein 8.216e-15 0.35
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.932e-14 0.31
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 2.598e-14 0.33
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.63e-14 0.40
MCLN3_HUMAN MCOLN3 Mucolipin-3 9.126e-14 0.37
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.695e-13 0.48
RNT1_ASPOR rntA Guanyl-specific ribonuclease T1 3.333e-13 0.29
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 4.803e-13 0.38
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 6.488e-13 0.31
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 6.861e-13 0.32
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 9.057e-13 0.42
CAH2_HUMAN CA2 Carbonic anhydrase 2 9.995e-13 0.48
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 2.317e-12 0.29
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 2.358e-12 0.34
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.573e-12 0.31
EZRI_HUMAN EZR Ezrin 7.163e-12 0.29
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 1.115e-11 0.38
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 1.115e-11 0.38
NICA_HUMAN NCSTN Nicastrin 1.115e-11 0.38
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 1.128e-11 0.38
PSN2_HUMAN PSEN2 Presenilin-2 1.165e-11 0.38
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.354e-11 0.38
MC5R_HUMAN MC5R Melanocortin receptor 5 1.418e-11 0.39
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 1.697e-11 0.37
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 2.94e-11 0.32
PSN1_HUMAN PSEN1 Presenilin-1 3.207e-11 0.38
FA10_HUMAN F10 Coagulation factor X 3.325e-11 0.43
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 3.562e-11 0.34
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.516e-11 0.38
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 8.675e-11 0.39
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.577e-10 0.28
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 2.769e-10 0.32
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 3.936e-10 0.33
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.522e-10 0.48
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 5.343e-10 0.33
UBCP1_HUMAN UBLCP1 Ubiquitin-like domain-containing CTD phosphatase 1 5.982e-10 0.29
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 9.219e-10 0.34
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 1.147e-09 0.31
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.191e-09 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.214e-09 0.36
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.242e-09 0.36
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.245e-09 0.47
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 1.286e-09 0.32
ITB7_HUMAN ITGB7 Integrin beta-7 1.4e-09 0.33
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.929e-09 0.39
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 3.589e-09 0.30
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 4.069e-09 0.63
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 5.225e-09 0.28
A6YCJ1_9METZ Astrosclerin-3 5.706e-09 0.38
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 6.634e-09 0.30
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 6.828e-09 0.36
CAN_CANAL NCE103 Carbonic anhydrase 7.021e-09 0.38
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 8.057e-09 0.40
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.192e-08 0.29
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.271e-08 0.33
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 1.409e-08 0.40
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 2e-08 0.28
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 2.076e-08 0.37
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 2.487e-08 0.32
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.521e-08 0.47
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.79e-08 0.38
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.156e-08 0.34
CAH2_BOVIN CA2 Carbonic anhydrase 2 3.253e-08 0.31
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.33e-08 0.41
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.775e-08 0.35
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.849e-08 0.48
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 4.403e-08 0.38
CYNT_HELPY cynT Carbonic anhydrase 4.406e-08 0.38
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.751e-08 0.44
ARBK1_BOVIN GRK2 Beta-adrenergic receptor kinase 1 5.32e-08 0.29
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 6.796e-08 0.35
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 6.937e-08 0.31
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 7.324e-08 0.33
LTC4S_HUMAN LTC4S Leukotriene C4 synthase 8.383e-08 0.34
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.092e-07 0.42
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.11e-07 0.33
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 1.12e-07 0.33
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.14e-07 0.33
B2CL1_HUMAN BCL2L1 Bcl-2-like protein 1 1.439e-07 0.35
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.505e-07 0.36
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.669e-07 0.32
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 1.702e-07 0.32
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 3.25e-07 0.41
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 3.326e-07 0.37
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 3.822e-07 0.37
MMP3_HUMAN MMP3 Stromelysin-1 4.277e-07 0.36
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 5.421e-07 0.36
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 5.488e-07 0.30
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 6.072e-07 0.29
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 7.761e-07 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 7.868e-07 0.39
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 9.753e-07 0.38
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 1.016e-06 0.28
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.024e-06 0.38
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.093e-06 0.33
APOB_HUMAN APOB Apolipoprotein B-100 1.175e-06 0.33
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 1.21e-06 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.227e-06 0.32
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.249e-06 0.36
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.354e-06 0.35
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.428e-06 0.35
CRFR1_HUMAN CRHR1 Corticotropin-releasing factor receptor 1 1.536e-06 0.31
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 1.71e-06 0.38
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.043e-06 0.31
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 2.094e-06 0.29
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 2.241e-06 0.39
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.392e-06 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 2.635e-06 0.34
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.861e-06 0.38
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 3.786e-06 0.32
CETP_HUMAN CETP Cholesteryl ester transfer protein 3.937e-06 0.34
Q5TU56_ANOGA 1272966 Carbonic anhydrase 4.541e-06 0.38
Q03732_HBV HBcAg Capsid protein 5.603e-06 0.31
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 5.947e-06 0.32
MC3R_HUMAN MC3R Melanocortin receptor 3 6.039e-06 0.38
CXL10_HUMAN CXCL10 C-X-C motif chemokine 10 6.327e-06 0.29
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 7.067e-06 0.31
CAN_YEAST NCE103 Carbonic anhydrase 7.962e-06 0.38

Pimozide

SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.935e-37 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.407e-31 1.00
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.937e-30 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.306e-25 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 3.406e-23 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.21e-18 1.00
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.088e-13 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.11e-12 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.201e-10 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.367e-08 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.12e-08 1.00
WDR48_HUMAN WDR48 WD repeat-containing protein 48 2.882e-08 1.00
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 4.014e-08 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.143e-07 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.21e-07 1.00
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.466e-07 1.00
XBP1_HUMAN XBP1 X-box-binding protein 1 0.000332 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.008377 1.00
HRH4_HUMAN HRH4 Histamine H4 receptor 0.1211 1.00
PLD1_RAT Pld1 Phospholipase D1 2.215e-171 0.61
PLD1_HUMAN PLD1 Phospholipase D1 4.217e-161 0.61
PLD2_HUMAN PLD2 Phospholipase D2 1.966e-152 0.61
CCR3_RAT Ccr3 C-C chemokine receptor type 3 3.889e-81 0.36
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 4.901e-69 0.36
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 3.849e-58 0.52
OPRX_HUMAN OPRL1 Nociceptin receptor 9.145e-51 0.59
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 6.551e-49 0.42
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.862e-44 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.061e-42 0.38
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.926e-41 0.40
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.681e-41 0.39
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 4.633e-40 0.38
O19067_PIG N-methyl-D-aspartate receptor 1.474e-39 0.31
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.333e-36 0.39
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.973e-35 0.49
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 6.228e-35 0.51
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.969e-33 0.66
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.495e-29 0.70
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.714e-28 0.41
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 2.609e-26 0.32
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.929e-25 0.49
DRD2_RAT Drd2 D(2) dopamine receptor 6.172e-25 0.58
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 8.057e-25 0.66
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.941e-24 0.46
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 3.516e-24 0.30
US28_HCMVA US28 G-protein coupled receptor homolog US28 2.944e-23 0.34
CALCA_RAT Calca Calcitonin gene-related peptide 1 4.989e-23 0.28
DRD4_RAT Drd4 D(4) dopamine receptor 1.678e-22 0.43
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.097e-22 0.45
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.254e-21 0.39
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.093e-21 0.49
DRD5_HUMAN DRD5 D(1B) dopamine receptor 5.275e-21 0.45
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.999e-20 0.44
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 2.021e-20 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.18e-19 0.67
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.344e-19 0.49
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 3.539e-19 0.36
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.933e-19 0.37
Q63380_RAT NET Transporter 1.667e-18 0.37
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.643e-18 0.61
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 4.486e-18 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 9.911e-18 0.70
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.11e-16 0.53
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 1.11e-16 0.48
Q9WTR4_RAT Slc6a2 Transporter 1.11e-16 0.37
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.11e-16 0.41
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.22e-16 0.61
HRH3_CAVPO HRH3 Histamine H3 receptor 3.331e-16 0.48
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.882e-16 0.39
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.421e-14 0.58
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.465e-14 0.70
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.577e-14 0.70
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.919e-14 0.36
HRH1_HUMAN HRH1 Histamine H1 receptor 3.941e-14 0.58
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 7.006e-14 0.49
DRD3_CHLAE DRD3 D(3) dopamine receptor 7.605e-14 0.51
CASB_RAT Csn2 Beta-casein 1.242e-13 0.30
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.922e-13 0.29
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 8.911e-13 0.36
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 9.552e-13 0.34
NK2R_HUMAN TACR2 Substance-K receptor 1.032e-12 0.51
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.228e-12 0.61
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.278e-12 0.39
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.28e-12 0.53
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.292e-12 0.70
HRH2_HUMAN HRH2 Histamine H2 receptor 1.389e-12 0.45
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.26e-12 0.49
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.548e-12 0.58
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 4.959e-12 0.29
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 5.012e-12 0.31
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.115e-12 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 8.017e-12 0.29
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 8.521e-12 0.39
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.141e-11 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.357e-11 0.53
HRH1_CAVPO HRH1 Histamine H1 receptor 7.257e-11 0.45
DRD5_RAT Drd5 D(1B) dopamine receptor 8.853e-11 0.32
MC4R_HUMAN MC4R Melanocortin receptor 4 1.695e-10 0.34
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.805e-10 0.48
DRD1_RAT Drd1 D(1A) dopamine receptor 2.336e-10 0.38
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.35e-10 0.48
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.791e-10 0.39
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 2.876e-10 0.49
RMLC_MYCTO rmlC dTDP-4-dehydrorhamnose 3,5-epimerase 3.238e-10 0.30
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 5.454e-10 0.58
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 6.557e-10 0.33
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 9.979e-10 0.33
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.103e-09 0.58
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 1.153e-09 0.43
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.28e-09 0.50
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 3.219e-09 0.58
DRD2_CHLAE DRD2 D(2) dopamine receptor 8.733e-09 0.51
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 2.359e-08 0.41
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 2.799e-08 0.49
CATS_HUMAN CTSS Cathepsin S 3.204e-08 0.43
LEF_BACAN lef Lethal factor 6.502e-08 0.32
ACHP_LYMST Acetylcholine-binding protein 8.736e-08 0.30
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 8.812e-08 0.33
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 1.155e-07 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.055e-07 0.29
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 5.094e-07 0.32
PAX8_HUMAN PAX8 Paired box protein Pax-8 7.028e-07 0.44
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.045e-07 0.37
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 7.436e-07 0.58
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 8.263e-07 0.58
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.056e-06 0.31
NK1R_HUMAN TACR1 Substance-P receptor 1.075e-06 0.45
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.578e-06 0.37
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.699e-06 0.36
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.051e-06 0.49
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 2.71e-06 0.49
RAMP1_HUMAN RAMP1 Receptor activity-modifying protein 1 3.37e-06 0.38
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.91e-06 0.29
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 3.974e-06 0.49
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 4.204e-06 0.33
OXDA_PIG DAO D-amino-acid oxidase 4.387e-06 0.31
HRH1_RAT Hrh1 Histamine H1 receptor 5.606e-06 0.32
DRD1_MOUSE Drd1 D(1A) dopamine receptor 7.11e-06 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 7.564e-06 0.58

Primaquine

PERL_BOVIN LPO Lactoperoxidase 3.937e-30 1.00
CASP6_HUMAN CASP6 Caspase-6 1.925e-06 1.00
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 3.75e-06 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 6.485e-06 1.00
PERM_HUMAN MPO Myeloperoxidase 0.0001999 1.00
RECA_MYCTU recA Protein RecA 0.0004927 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.0008604 1.00
CASP7_HUMAN CASP7 Caspase-7 0.003257 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.501 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.5147 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.9982 1.00
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.968e-41 0.48
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 3.824e-40 0.32
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 2.776e-23 0.37
HASP_HUMAN HASPIN Serine/threonine-protein kinase haspin 1.08e-21 0.31
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 4.416e-20 0.45
RBP_CHICK Riboflavin-binding protein 5.429e-20 0.32
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 9.187e-18 0.33
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 5.474e-17 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 2.22e-16 0.37
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.101e-11 0.44
HRP1_PLAFA Histidine-rich protein PFHRP-II 7.18e-10 0.66
PDE4A_HUMAN PDE4A cAMP-specific 3',5'-cyclic phosphodiesterase 4A 1.486e-07 0.37
TF65_HUMAN RELA Transcription factor p65 2.636e-07 0.45
PLM1_PLAFA Plasmepsin-1 3.894e-07 0.43
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 7.633e-07 0.32
S10A4_HUMAN S100A4 Protein S100-A4 7.758e-07 0.46
BXA1_CLOBO botA Botulinum neurotoxin type A 9.613e-07 0.33
DYR1_ECOLX dhfrI Dihydrofolate reductase type 1 2.577e-06 0.33
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 3.126e-06 0.60
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 6.855e-06 0.37
STABP_HUMAN STAMBP STAM-binding protein 8.994e-06 0.29

Ethinylestradiol

ESR1_HUMAN ESR1 Estrogen receptor 7.447e-30 1.00
ESR2_HUMAN ESR2 Estrogen receptor beta 7.779e-23 1.00
STS_HUMAN STS Steryl-sulfatase 8.26e-161 0.72
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.416e-77 0.59
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 4.08e-74 0.58
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.663e-67 0.70
Q95MF8_PIG Sulfotransferase 2.087e-63 0.38
Q690N0_BOVIN PGR Progesterone receptor 1.921e-56 0.58
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.304e-39 0.60
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.466e-35 0.58
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.375e-31 0.58
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 8.807e-28 0.44
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 3.507e-26 0.42
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 1.116e-25 0.41
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 9.841e-25 0.30
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 8.089e-24 0.29
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 7.049e-23 0.58
ANDR_RAT Ar Androgen receptor 1.194e-21 0.76
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.648e-18 0.36
ESR1_MOUSE Esr1 Estrogen receptor 1.024e-17 0.58
ESR2_MOUSE Esr2 Estrogen receptor beta 1.024e-17 0.58
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.11e-16 0.42
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.665e-15 0.58
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.776e-15 0.56
PRGR_RAT Pgr Progesterone receptor 7.039e-14 0.30
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.802e-13 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.54e-12 0.58
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 7.904e-12 0.38
NK1R_RAT Tacr1 Substance-P receptor 2.54e-11 0.37
ESR1_RAT Esr1 Estrogen receptor 1.401e-09 0.58
PRGR_RABIT PGR Progesterone receptor 1.955e-09 0.30
CP19A_HUMAN CYP19A1 Aromatase 2.603e-09 0.58
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.148e-08 0.58
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 2.007e-07 0.58
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 5.369e-07 0.31
ESR2_RAT Esr2 Estrogen receptor beta 6.144e-07 0.58
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.471e-06 0.58
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 3.597e-06 0.58
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.78e-06 0.48
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 5.529e-06 0.42

Gatifloxacin

PARC_STAAU parC DNA topoisomerase 4 subunit A 1.664e-29 1.00
GYRA_MYCTU gyrA DNA gyrase subunit A 1.664e-25 1.00
STRP_STRP1 ska Streptokinase A 4.132e-06 1.00
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 0.002244 1.00
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 0.03202 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 0.132 1.00
Q47245_ECOLX gyrA DNA gyrase subunit A 1.15e-84 0.72
ACEA_MYCTU icl Isocitrate lyase 2.127e-81 0.59
C3SLN2_ECOLX gyrB DNA gyrase subunit B 2.815e-73 0.72
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 2.789e-51 0.41
GLYCP_NIPAV G Glycoprotein G 7.602e-32 0.32
GYRA_STAAU gyrA DNA gyrase subunit A 4.628e-29 0.73
DPO3_BACSU polC DNA polymerase III PolC-type 3.548e-26 0.49
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 8.827e-20 0.38
DPO1_THEAQ polA DNA polymerase I, thermostable 9.295e-19 0.39
GYRB_STAAU gyrB DNA gyrase subunit B 2.575e-17 0.73
GYRA_ECOLI gyrA DNA gyrase subunit A 1.965e-14 0.73
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.273e-12 0.44
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.859e-09 0.41
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.02e-08 0.44
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 1.129e-07 0.28
PARE_STAAU parE DNA topoisomerase 4 subunit B 1.806e-07 0.51
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 1.474e-06 0.31

Norfloxacin

PARC_STAAU parC DNA topoisomerase 4 subunit A 1.517e-27 1.00
ACEA_MYCTU icl Isocitrate lyase 3.75e-92 0.67
GLYCP_NIPAV G Glycoprotein G 1.039e-84 0.49
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 3.352e-80 0.64
Q47245_ECOLX gyrA DNA gyrase subunit A 2.092e-68 0.67
C3SLN2_ECOLX gyrB DNA gyrase subunit B 3.181e-59 0.67
DPO3_BACSU polC DNA polymerase III PolC-type 1.856e-30 0.51
Q76353_9HIV1 Integrase 7.934e-30 0.43
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 4.184e-19 0.42
Q7ZJM1_9HIV1 pol Integrase 9.992e-16 0.43
DPO1_THEAQ polA DNA polymerase I, thermostable 2.442e-15 0.31
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.548e-11 0.36
PARE_STAAU parE DNA topoisomerase 4 subunit B 1.358e-09 0.67
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2.37e-09 0.33
1433G_HUMAN YWHAG 14-3-3 protein gamma 3.044e-09 0.33
GYRA_ECOLI gyrA DNA gyrase subunit A 6.847e-08 0.67
GYRA_MYCTU gyrA DNA gyrase subunit A 2.395e-07 0.38
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.977e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.977e-07 0.29
GYRA_STAAU gyrA DNA gyrase subunit A 7.07e-07 0.67
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.806e-06 0.33
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 1.921e-06 0.33
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 4.472e-06 0.65
STRP_STRP1 ska Streptokinase A 5.623e-06 0.60
BRPF1_HUMAN BRPF1 Peregrin 8.684e-06 0.33

Pilocarpine

ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.773e-24 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 7.261e-14 1.00
ACM1_MOUSE Chrm1 Muscarinic acetylcholine receptor M1 4.142e-12 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.782e-11 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
CPXA_PSEPU camC Camphor 5-monooxygenase 8.882e-16 0.30

Hydrochlorothiazide

Q5TU56_ANOGA 1272966 Carbonic anhydrase 8.948e-24 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 7.836e-22 1.00
B2V8E3_SULSY Carbonate dehydratase 4.354e-17 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 4.354e-17 1.00
A6YCJ1_9METZ Astrosclerin-3 3.331e-16 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.413e-11 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.727e-11 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.707e-21 0.36
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.032e-14 0.35
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 5.04e-14 0.57
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.426e-13 0.57
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 6.43e-12 0.57
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.041e-11 0.36
GRIA2_RAT Gria2 Glutamate receptor 2 2.76e-09 0.51
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.925e-09 0.57
CAH12_HUMAN CA12 Carbonic anhydrase 12 6.484e-09 0.72
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.95e-08 0.57
CAH7_HUMAN CA7 Carbonic anhydrase 7 6.819e-08 0.58
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.797e-07 0.72
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.698e-07 0.57
CAH_METTE Carbonic anhydrase 9.875e-07 0.33

Diphenhydramine

SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 8.714e-23 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.776e-14 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 3.74e-11 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.053e-11 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.485e-09 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.45e-09 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.993e-07 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.788e-07 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 8.835e-07 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.842e-07 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.063e-06 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 6.014e-06 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0001981 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.006402 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.01635 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.01933 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.03291 1.00
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.006e-73 0.35
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.405e-62 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.14e-60 0.63
Q5TIX5_MYCSM atpE ATP synthase subunit c 1.291e-51 0.28
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 9.276e-47 0.59
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 1.802e-46 0.33
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 6.994e-36 0.35
ATPL_BACP3 atpE ATP synthase subunit c 1.377e-35 0.28
CALM_BOVIN CALM Calmodulin 1.425e-21 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.238e-20 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.839e-20 0.33
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.194e-18 0.73
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.11e-16 0.42
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.776e-15 0.34
Q9WTR4_RAT Slc6a2 Transporter 2.809e-14 0.40
ERG7_PNECA ERG7 Lanosterol synthase 2.986e-13 0.29
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 4.657e-13 0.30
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 8.923e-10 0.33
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 1.628e-09 0.29
ATP6_MYCTU atpB ATP synthase subunit a 4.765e-09 0.30
ATPA_MYCTU atpA ATP synthase subunit alpha 4.765e-09 0.30
ATPB_MYCTU atpD ATP synthase subunit beta 4.765e-09 0.30
ATPE_MYCTU atpC ATP synthase epsilon chain 4.765e-09 0.30
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 4.765e-09 0.30
ATPF_MYCTU atpF ATP synthase subunit b 4.765e-09 0.30
ATPG_MYCTU atpG ATP synthase gamma chain 4.765e-09 0.30
ATPL_MYCTU atpE ATP synthase subunit c 4.765e-09 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 7.882e-09 0.42
CALM1_HUMAN CALM1 Calmodulin-1 8.846e-09 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.143e-08 0.33
HRH1_RAT Hrh1 Histamine H1 receptor 1.954e-08 0.73
HRH1_HUMAN HRH1 Histamine H1 receptor 4.046e-08 0.73
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 7.551e-08 0.44
ACHP_LYMST Acetylcholine-binding protein 7.612e-07 0.39
NORA_STAAU norA Quinolone resistance protein NorA 1.606e-06 0.31
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.681e-06 0.29
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.835e-06 0.34
HRH2_HUMAN HRH2 Histamine H2 receptor 2.888e-06 0.73
Q63380_RAT NET Transporter 3.271e-06 0.34
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.358e-06 0.50
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 4.269e-06 0.42
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.982e-06 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 7.812e-06 0.41

Tolterodine

ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 4.197e-20 1.00
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.805e-11 1.00
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 6.422e-08 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 6.444e-07 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.073e-05 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.051e-05 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.0194 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.03858 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 0.07089 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.1848 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.2346 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9985 1.00
PPO1_AGABI PPO1 Polyphenol oxidase 1 6.686e-21 0.38
CALM_BOVIN CALM Calmodulin 2.506e-11 0.30
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 1.566e-08 0.28
GLI1_HUMAN GLI1 Zinc finger protein GLI1 2.287e-08 0.30
Q49PX0_9POXV N1L N1L 2.8e-08 0.29
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 9.833e-08 0.32
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.213e-06 0.28
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7.434e-06 0.30

Diphenoxylate

KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 3.251e-19 1.00
NK2R_MOUSE Tacr2 Substance-K receptor 1.024e-62 0.33
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.129e-49 0.45
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 7.133e-46 0.44
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 3.026e-44 0.32
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.738e-40 0.45
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 3.175e-37 0.54
DCMC_MOUSE Mlycd Malonyl-CoA decarboxylase, mitochondrial 6.2e-28 0.32
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 2.847e-23 0.29
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.655e-21 0.53
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.101e-20 0.38
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.306e-20 0.44
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.125e-17 0.38
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 2.22e-16 0.30
HRH2_HUMAN HRH2 Histamine H2 receptor 6.661e-16 0.38
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 3.109e-15 0.38
NK2R_BOVIN TACR2 Substance-K receptor 3.664e-15 0.29
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 7.105e-15 0.28
HRH1_HUMAN HRH1 Histamine H1 receptor 7.327e-15 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.437e-15 0.44
MEN1_HUMAN MEN1 Menin 2.132e-14 0.31
CALM_BOVIN CALM Calmodulin 7.816e-14 0.38
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.359e-13 0.33
NK1R_HUMAN TACR1 Substance-P receptor 3.023e-13 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.763e-13 0.53
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.075e-12 0.44
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.628e-12 0.29
NK1R_CAVPO TACR1 Substance-P receptor 6.225e-12 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.514e-11 0.42
NK2R_HUMAN TACR2 Substance-K receptor 2.161e-11 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.979e-11 0.42
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.442e-11 0.42
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 8.4e-11 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 9.632e-11 0.38
VACHT_TETCF Vesicular acetylcholine transporter 1.553e-10 0.34
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.716e-10 0.44
Q63380_RAT NET Transporter 1.992e-10 0.43
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.79e-10 0.30
OPRX_HUMAN OPRL1 Nociceptin receptor 4.968e-10 0.40
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.516e-10 0.61
NK2R_RAT Tacr2 Substance-K receptor 9.031e-10 0.32
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.012e-09 0.28
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.275e-09 0.41
NK1R_MERUN TACR1 Substance-P receptor 3.634e-09 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.547e-09 0.41
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 5.671e-09 0.44
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.606e-08 0.30
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 3.153e-08 0.33
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 5.519e-08 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 9.578e-08 0.29
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.072e-07 0.32
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.676e-07 0.34
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 3.436e-07 0.31
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 3.738e-07 0.31
TSHR_HUMAN TSHR Thyrotropin receptor 3.808e-07 0.30
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 6.465e-07 0.30
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 8.335e-07 0.30
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 8.443e-07 0.40
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.204e-06 0.29
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.535e-06 0.30
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.171e-06 0.30
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.057e-06 0.49
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.258e-06 0.32

Tegaserod

5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.11e-16 1.00
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 4.723e-07 1.00
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 3.678e-06 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 8.513e-05 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0002544 1.00
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 0.0002847 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.007956 1.00
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 0.05302 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 0.06322 1.00
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.605e-48 0.44
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.684e-42 0.44
PA2A1_NAJMO Acidic phospholipase A2 CM-I 1.023e-37 0.30
SPRE_HUMAN SPR Sepiapterin reductase 2.072e-28 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.4e-26 0.38
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 7.018e-21 0.30
ASAH1_RAT Asah1 Acid ceramidase 5.226e-19 0.31
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 5.976e-18 0.33
ENV_MMTVG env Envelope glycoprotein gp70 1.11e-16 0.31
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 3.331e-16 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.665e-15 0.42
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 5.551e-15 0.33
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 5.773e-15 0.34
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 1.055e-14 0.33
GAG_AVIER gag Gag polyprotein 2.232e-14 0.31
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 1.293e-13 0.33
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.888e-13 0.38
MTR1B_CHICK Melatonin receptor type 1B 2.551e-13 0.29
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 5.472e-12 0.34
CHLE_HUMAN BCHE Cholinesterase 1.793e-11 0.38
KI20A_HUMAN KIF20A Kinesin-like protein KIF20A 8.853e-11 0.32
ACES_HUMAN ACHE Acetylcholinesterase 1.056e-10 0.38
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 3.598e-10 0.33
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 4.983e-10 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.759e-09 0.42
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.11e-09 0.46
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 4.765e-09 0.34
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.763e-09 0.39
TLR4_HUMAN TLR4 Toll-like receptor 4 1.111e-08 0.37
BGLR_HUMAN GUSB Beta-glucuronidase 1.421e-08 0.33
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.67e-08 0.40
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.226e-08 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 7.127e-08 0.29
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.772e-08 0.39
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 9.553e-08 0.55
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.124e-07 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.024e-07 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.513e-07 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 5.694e-07 0.38
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.914e-07 0.32
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 7.857e-07 0.43
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.537e-06 0.29
PAO1_MAIZE MPAO1 Polyamine oxidase 1 1.661e-06 0.35
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 1.869e-06 0.31
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.39e-06 0.37
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 5.99e-06 0.29
SYUA_HUMAN SNCA Alpha-synuclein 8.473e-06 0.32
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 9.275e-06 0.33
HDAC2_HUMAN HDAC2 Histone deacetylase 2 9.762e-06 0.41
TLR1_MOUSE Tlr1 Toll-like receptor 1 9.817e-06 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 9.817e-06 0.29

Levocabastine

NTR2_RAT Ntsr2 Neurotensin receptor type 2 3.331e-16 1.00
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 7.994e-66 0.34
Q6P1E0_MOUSE Syk Tyrosine-protein kinase 3.822e-30 0.33
OPRX_RAT Oprl1 Nociceptin receptor 2.595e-21 0.31
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 2.33e-19 0.34
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 4.655e-18 0.37
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 6.514e-13 0.36
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 7.248e-13 0.36
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.472e-12 0.36
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.518e-12 0.36
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 4.631e-11 0.41
VACHT_TETCF Vesicular acetylcholine transporter 7.764e-11 0.35
OPRX_HUMAN OPRL1 Nociceptin receptor 9.648e-11 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.195e-10 0.32
NK1R_HUMAN TACR1 Substance-P receptor 3.721e-10 0.37
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 5.289e-10 0.31
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.836e-10 0.36
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.06e-09 0.32
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.381e-08 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.315e-07 0.35
NK3R_HUMAN TACR3 Neuromedin-K receptor 5.013e-07 0.35
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 5.904e-07 0.28
OPRD_HUMAN OPRD1 Delta-type opioid receptor 7.17e-07 0.38
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 1.649e-06 0.35
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 2.448e-06 0.39

Bethanechol

Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 8.882e-16 1.00
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 0.008404 1.00
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 4.474e-39 0.31

Trichlormethiazide

CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.221e-15 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.775e-15 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 2.655e-13 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.509e-10 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.003e-08 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.005e-08 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.212e-08 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.047e-06 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.785e-06 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.173e-05 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 0.0002305 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.188e-21 0.36
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.11e-16 0.57
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.443e-15 0.57
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.278e-11 0.36
B2V8E3_SULSY Carbonate dehydratase 2.228e-11 0.57
Q31FD6_HYDCU Carbonic anhydrase, alpha family 2.228e-11 0.57
A6YCJ1_9METZ Astrosclerin-3 8.558e-11 0.57
CAH4_BOVIN CA4 Carbonic anhydrase 4 6.356e-07 0.33
GRIA2_RAT Gria2 Glutamate receptor 2 1.05e-06 0.56
CAH_METTE Carbonic anhydrase 3.285e-06 0.30
ACE_RAT Ace Angiotensin-converting enzyme 3.546e-06 0.45

Cinacalcet

CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.109e-15 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 6.82e-11 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.01414 1.00
CASR_RAT Casr Extracellular calcium-sensing receptor 2.466e-98 0.44
GPR52_HUMAN GPR52 G-protein coupled receptor 52 3.953e-83 0.35
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 4.449e-37 0.29
PDS_SYNE7 pds 15-cis-phytoene desaturase 6.322e-36 0.38
DEF_STAAM def Peptide deformylase 8.577e-24 0.50
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.11e-16 0.34
CP51_SORBI CYP51 Obtusifoliol 14-alpha demethylase 3.331e-16 0.31
PPAP_HUMAN ACP3 Prostatic acid phosphatase 8.882e-16 0.33
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.221e-15 0.34
CCL2_HUMAN CCL2 C-C motif chemokine 2 4.219e-15 0.37
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 3.086e-14 0.32
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 5.075e-12 0.33
MRGX2_HUMAN MRGPRX2 Mas-related G-protein coupled receptor member X2 5.743e-12 0.29
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 9.758e-12 0.30
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 1.349e-11 0.29
CRTM_STAAU crtM 4,4'-diapophytoene synthase 1.58e-11 0.35
T1QYY3_9HIV1 int Integrase 7.655e-11 0.29
PETD_SPIOL petD Cytochrome b6-f complex subunit 4 1.819e-10 0.36
Q63380_RAT NET Transporter 3.938e-10 0.34
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.349e-10 0.60
NK1R_HUMAN TACR1 Substance-P receptor 2.899e-09 0.40
SHH_MOUSE Shh Sonic hedgehog protein 3.257e-09 0.36
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 4.96e-09 0.29
PSBA_MARPO psbA Photosystem II protein D1 5.048e-09 0.28
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 6.645e-09 0.32
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 2.02e-08 0.33
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.595e-08 0.35
RXFP1_HUMAN RXFP1 Relaxin receptor 1 2.719e-08 0.34
PANK1_HUMAN PANK1 Pantothenate kinase 1 4.951e-08 0.28
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 6.844e-08 0.35
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.178e-07 0.28
SCYD_MAGO7 SDH1 Scytalone dehydratase 1.987e-07 0.35
OXDA_MOUSE Dao D-amino-acid oxidase 2.137e-07 0.36
ACOD_HUMAN SCD Acyl-CoA desaturase 2.166e-07 0.32
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 2.27e-07 0.32
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 2.358e-07 0.31
KCNN2_RAT Kcnn2 Small conductance calcium-activated potassium channel protein 2 2.68e-07 0.28
PANK3_HUMAN PANK3 Pantothenate kinase 3 2.869e-07 0.28
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 3.977e-07 0.39
SUCR1_HUMAN SUCNR1 Succinate receptor 1 8.177e-07 0.33
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 9.709e-07 0.31
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 2.2e-06 0.32
IDE_HUMAN IDE Insulin-degrading enzyme 3.77e-06 0.46
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 4.384e-06 0.30
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 7.823e-06 0.29
STABP_HUMAN STAMBP STAM-binding protein 8.994e-06 0.29

Benzocaine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.343e-14 1.00
DCOR_MOUSE Odc1 Ornithine decarboxylase 1.69e-91 0.41
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 1.235e-67 0.36
ACRO_HUMAN ACR Acrosin 8.458e-55 0.50
PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 2.422e-46 0.37
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 7.618e-39 0.44
ECR_CHITE EcR Ecdysone receptor 1.947e-38 0.30
ECR_HELVI EcR Ecdysone receptor 1.947e-38 0.30
O45117_CHITE USP-1 Ultraspiracle 1.947e-38 0.30
Q6IVK1_PLOIN USP 1.947e-38 0.30
Q6RVD3_PLOIN Ecdysone receptor 1.947e-38 0.30
Q7SIF6_HELVI Gene regulation protein 1.947e-38 0.30
Q8I1M8_CHISP CsUSP Ultraspiracle 1.947e-38 0.30
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 1.947e-38 0.30
Q962I5_LUCCU Ultraspiracle protein 1.947e-38 0.30
USP_CHOFU USP Protein ultraspiracle homolog 1.947e-38 0.30
MAX_HUMAN MAX Protein max 8.333e-36 0.28
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 1.038e-35 0.36
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.488e-33 0.44
Q4Q5W4_LEIMA Putative squalene synthase 5.014e-28 0.46
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 9.991e-27 0.44
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 1.098e-26 0.31
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.666e-26 0.38
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 1.669e-26 0.33
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 2.424e-26 0.38
BGAL_ASPNG lacA Beta-galactosidase 9.719e-24 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.023e-22 0.39
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 1.313e-22 0.35
EST1_RABIT Liver carboxylesterase 1 9.926e-20 0.36
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 1.109e-19 0.33
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.98e-19 0.31
Q4W6C8_LEPDE LdUSP Ultraspiracle 3.691e-19 0.30
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 3.691e-19 0.30
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 5.777e-19 0.42
ERG1_RAT Sqle Squalene monooxygenase 2.375e-18 0.52
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.793e-17 0.70
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 4.126e-17 0.56
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.11e-16 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.11e-16 0.36
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 2.22e-16 0.31
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 3.331e-16 0.49
Q31945_CHEAL Chloroplast thylakoid membrane protein (psbA) 3.331e-16 0.31
Q9GSG8_AEDAE Ultraspiracle isoform-A 5.551e-16 0.30
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.443e-15 0.42
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 3.331e-15 0.59
GATA4_MOUSE Gata4 Transcription factor GATA-4 5.884e-15 0.33
LOXL4_HUMAN LOXL4 Lysyl oxidase homolog 4 5.884e-15 0.28
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 5.884e-15 0.33
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 7.105e-15 0.33
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 7.105e-15 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 8.438e-15 0.35
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.721e-14 0.56
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 2.753e-14 0.31
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 3.086e-14 0.42
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 3.486e-14 0.37
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 7.627e-14 0.41
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.463e-13 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.841e-13 0.53
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.905e-13 0.32
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 3.595e-13 0.45
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.17e-12 0.32
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 1.789e-12 0.38
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.274e-12 0.39
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 4.258e-12 0.41
SENP1_HUMAN SENP1 Sentrin-specific protease 1 4.299e-12 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.411e-12 0.70
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 6.966e-12 0.29
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.16e-12 0.35
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 9.7e-12 0.29
TDT_HUMAN DNTT DNA nucleotidylexotransferase 9.7e-12 0.29
E3UJZ5_SPOLI Ecdysone receptor 1.688e-11 0.31
RARB_HUMAN RARB Retinoic acid receptor beta 1.842e-11 0.44
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.909e-11 0.47
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.92e-11 0.31
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.424e-11 0.37
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 2.943e-11 0.30
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.761e-11 0.46
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 4.003e-11 0.38
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 4.786e-11 0.42
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.491e-11 0.40
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.004e-10 0.43
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.068e-10 0.31
RS27_HUMAN RPS27 40S ribosomal protein S27 1.369e-10 0.28
STS_HUMAN STS Steryl-sulfatase 1.898e-10 0.39
H9B8T9_CAPHI CTSB Cathepsin B 1.999e-10 0.34
RARA_HUMAN RARA Retinoic acid receptor alpha 2.17e-10 0.44
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.53e-10 0.33
ELNE_HUMAN ELANE Neutrophil elastase 3.968e-10 0.39
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 4.057e-10 0.31
EST2_HUMAN CES2 Cocaine esterase 5.276e-10 0.36
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 5.42e-10 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 5.618e-10 0.35
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 7.019e-10 0.38
TLR4_HUMAN TLR4 Toll-like receptor 4 7.789e-10 0.31
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 8.044e-10 0.32
CAH12_HUMAN CA12 Carbonic anhydrase 12 9.76e-10 0.70
ECR_LUCCU EcR Ecdysone receptor 1.021e-09 0.30
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 1.106e-09 0.38
DHPS_ECOLI folP Dihydropteroate synthase 1.273e-09 0.38
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 1.415e-09 0.31
GSTM2_HUMAN GSTM2 Glutathione S-transferase Mu 2 1.603e-09 0.39
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.76e-09 0.30
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 2.37e-09 0.33
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.158e-09 0.42
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.66e-09 0.70
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 4.438e-09 0.28
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 5.97e-09 0.50
TRY1_HUMAN PRSS1 Trypsin-1 7.712e-09 0.50
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 8.426e-09 0.45
DNAB_MYCTU dnaB Replicative DNA helicase 9.731e-09 0.42
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.369e-08 0.39
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.403e-08 0.46
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.428e-08 0.30
Q8IL32_PLAF7 Heat shock protein 90, putative 1.757e-08 0.56
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.892e-08 0.70
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.959e-08 0.45
RECA_MYCTU recA Protein RecA 2.326e-08 0.43
LUCI_PHOPY Luciferin 4-monooxygenase 2.571e-08 0.37
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.666e-08 0.70
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 3.649e-08 0.33
ACES_HUMAN ACHE Acetylcholinesterase 3.997e-08 0.42
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 4.221e-08 0.35
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 4.531e-08 0.36
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 5.3e-08 0.35
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.524e-08 0.45
MGLL_RAT Mgll Monoglyceride lipase 7.272e-08 0.35
CAH13_MOUSE Ca13 Carbonic anhydrase 13 7.631e-08 0.36
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.031e-07 0.36
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.129e-07 0.34
STRP_STRP1 ska Streptokinase A 1.25e-07 0.44
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.494e-07 0.37
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.532e-07 0.42
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.558e-07 0.32
XBP1_HUMAN XBP1 X-box-binding protein 1 1.6e-07 0.33
VGFR1_MOUSE Flt1 Vascular endothelial growth factor receptor 1 2.193e-07 0.29
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.869e-07 0.28
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.1e-07 0.42
PLMN_RAT Plg Plasminogen 3.351e-07 0.30
ACRO_PIG ACR Acrosin 3.537e-07 0.35
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 4.172e-07 0.56
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 4.268e-07 0.29
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 4.38e-07 0.35
CLAT_RAT Chat Choline O-acetyltransferase 4.905e-07 0.29
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 5.1e-07 0.35
ODP2_MYCTU dlaT Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 5.174e-07 0.29
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 6.027e-07 0.31
BGAL_HUMAN GLB1 Beta-galactosidase 7.045e-07 0.29
O77240_CHOFU EcR Ecdysone receptor isoform A 7.091e-07 0.30
TLR4_MOUSE Tlr4 Toll-like receptor 4 7.619e-07 0.32
TLR1_MOUSE Tlr1 Toll-like receptor 1 8.801e-07 0.35
TLR2_MOUSE Tlr2 Toll-like receptor 2 8.801e-07 0.35
5NTD_HUMAN NT5E 5'-nucleotidase 9.433e-07 0.32
GYRB_MYCSM gyrB DNA gyrase subunit B 1.27e-06 0.31
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.294e-06 0.33
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 1.334e-06 0.33
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.346e-06 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.367e-06 0.41
CP19A_HUMAN CYP19A1 Aromatase 1.467e-06 0.45
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.618e-06 0.43
DYR_PNECA Dihydrofolate reductase 1.635e-06 0.38
EST1_HUMAN CES1 Liver carboxylesterase 1 1.799e-06 0.36
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.849e-06 0.31
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.977e-06 0.29
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 2.001e-06 0.33
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.099e-06 0.36
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.26e-06 0.29
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 2.392e-06 0.43
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.849e-06 0.29
PRTN3_HUMAN PRTN3 Myeloblastin 3.161e-06 0.35
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.025e-06 0.46
FA10_BOVIN F10 Coagulation factor X 4.282e-06 0.29
ECR_BOMMO EcR Ecdysone receptor 5.117e-06 0.31
CAH_METTE Carbonic anhydrase 5.875e-06 0.29
LUCI_AQULA Luciferin 4-monooxygenase 6.235e-06 0.29
Q91H74_9FLAV Genome polyprotein 6.965e-06 0.32
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 7.229e-06 0.39
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.69e-06 0.29
LYOX_HUMAN LOX Protein-lysine 6-oxidase 7.85e-06 0.28
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 7.864e-06 0.39
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 8.196e-06 0.37
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 9.511e-06 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 9.702e-06 0.33

Sibutramine

SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.079e-13 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.601e-12 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 7.576e-09 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.399e-14 0.32
CHKA_HUMAN CHKA Choline kinase alpha 1.794e-07 0.30
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 9.908e-07 0.35
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.03e-06 0.29

Iloprost

PI2R_HUMAN PTGIR Prostacyclin receptor 2.531e-13 1.00
PI2R_RAT Ptgir Prostacyclin receptor 1.337e-10 1.00
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 0.01054 1.00
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 7.498e-54 0.35
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.397e-51 0.35
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 7.381e-50 0.35
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 2.707e-42 0.35
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 9.324e-40 0.35
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 6.782e-33 0.35
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.199e-22 0.35
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.285e-21 0.35
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 6.721e-21 0.46
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 3.075e-19 0.35
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.22e-16 0.35
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 3.463e-12 0.35
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 6.598e-12 0.35
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 5.38e-09 0.44
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 7.713e-08 0.35
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 3.352e-07 0.35

Promethazine

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.846e-13 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.137e-12 1.00
PRIO_HUMAN PRNP Major prion protein 2.339e-10 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 3.455e-10 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.748e-08 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.288e-07 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.162e-06 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.228e-06 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 2.493e-06 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 6.366e-06 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.201e-06 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.199e-05 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.149e-05 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 9.404e-05 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.000286 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0008228 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.0008278 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.001881 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.002498 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.003145 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.0114 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.01811 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.03528 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.04376 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.05157 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.235 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.3245 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.3304 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.082e-117 0.51
PRIO_MOUSE Prnp Major prion protein 1.573e-54 0.43
TYTR_TRYCR TPR Trypanothione reductase 1.328e-35 0.43
CALM_BOVIN CALM Calmodulin 3.712e-27 0.43
LYSC1_RAT Lyz1 Lysozyme C-1 1.567e-26 0.33
CHLE_HUMAN BCHE Cholinesterase 3.655e-26 0.74
ITAM_HUMAN ITGAM Integrin alpha-M 4.502e-26 0.32
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.689e-22 0.43
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.83e-21 0.33
BGLR_RAT Gusb Beta-glucuronidase 1.541e-20 0.33
EBPL_HUMAN EBPL Emopamil-binding protein-like 1.541e-20 0.33
CALM1_HUMAN CALM1 Calmodulin-1 2.189e-20 0.43
NOX1_HUMAN NOX1 NADPH oxidase 1 6.414e-20 0.39
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 1.183e-13 0.38
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 8.628e-12 0.38
DEF_STAAM def Peptide deformylase 5.278e-11 0.30
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 2.8e-08 0.29
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 4.702e-08 0.43
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.161e-07 0.31
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 4.404e-07 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.702e-06 0.43
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 4.877e-06 0.31

Felodipine

AA3R_HUMAN ADORA3 Adenosine receptor A3 8.023e-12 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 7.394e-09 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.335e-08 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 2.811e-05 1.00
NR1H4_HUMAN NR1H4 Bile acid receptor 0.02329 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 7.504e-195 0.78
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.275e-136 0.58
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 7.258e-114 0.58
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 1.15e-73 0.39
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 7.788e-70 0.51
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.303e-64 0.40
Q03732_HBV HBcAg Capsid protein 1.081e-57 0.40
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.279e-56 0.61
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 7.075e-48 0.61
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 2.376e-46 0.46
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 4.448e-41 0.61
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 1.688e-39 0.53
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.106e-36 0.60
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.152e-36 0.37
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 1.039e-35 0.37
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 5.395e-30 0.37
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 2.995e-26 0.51
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.329e-18 0.61
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.979e-18 0.33
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.22e-16 0.42
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.054e-14 0.43
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 4.331e-13 0.37
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 5.245e-13 0.32
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.196e-11 0.28
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 5.033e-11 0.43
ACES_HUMAN ACHE Acetylcholinesterase 1.905e-10 0.39
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.354e-10 0.61
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 2.549e-10 0.51
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 3.469e-10 0.34
Q7JHP9_MACMU SLC6A3 Transporter 6.262e-10 0.29
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 6.554e-10 0.31
SC6A4_MACMU SLC6A4 Sodium-dependent serotonin transporter 9.563e-10 0.29
DPOLB_HUMAN POLB DNA polymerase beta 2.639e-09 0.29
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 3.598e-09 0.29
ENPL_HUMAN HSP90B1 Endoplasmin 9.602e-09 0.30
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.226e-08 0.38
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 8.004e-08 0.41
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.016e-07 0.35
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 2.199e-07 0.39
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.541e-07 0.29
THAS_RAT Tbxas1 Thromboxane-A synthase 3.048e-07 0.31
ILVB_ARATH ALS Acetolactate synthase, chloroplastic 3.451e-07 0.30
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 4.905e-07 0.29
AA1R_RAT Adora1 Adenosine receptor A1 7.582e-07 0.53
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.028e-06 0.34
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.474e-06 0.34
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.495e-06 0.61
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1.742e-06 0.30
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.999e-06 0.31
TLR4_MOUSE Tlr4 Toll-like receptor 4 2.4e-06 0.28
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 2.784e-06 0.58
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.059e-06 0.35
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.135e-06 0.61
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.037e-06 0.28
CLK3_HUMAN CLK3 Dual specificity protein kinase CLK3 8.815e-06 0.32
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 9.214e-06 0.34

Butenafine

ACES_HUMAN ACHE Acetylcholinesterase 1.357e-09 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.008e-06 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.000169 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.005645 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.04808 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.0516 1.00
INAR1_HUMAN IFNAR1 Interferon alpha/beta receptor 1 4.048e-41 0.33
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.864e-39 0.33
CRTN_STAA3 crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 3.409e-38 0.33
CRTN_STAAW crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 8.872e-32 0.33
CRTN_STAAE crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 2.61e-31 0.48
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 2.272e-28 0.43
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.824e-20 0.33
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.284e-19 0.37
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.663e-19 0.40
ERG1_HUMAN SQLE Squalene monooxygenase 2.22e-16 0.49
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 6.661e-16 0.33
FTSZ_ECOLI ftsZ Cell division protein FtsZ 1.665e-15 0.29
FTSZ_STAAU ftsZ Cell division protein FtsZ 1.665e-15 0.29
CHIT1_HUMAN CHIT1 Chitotriosidase-1 1.119e-11 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.457e-11 0.30
CHIA_MOUSE Chia Acidic mammalian chitinase 1.291e-10 0.30
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.807e-09 0.38
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 1.878e-08 0.40
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.288e-08 0.31
CHIT1_MOUSE Chit1 Chitotriosidase-1 1.197e-07 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 3.89e-07 0.40
EST1_PIG Liver carboxylesterase 7.646e-07 0.33
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.63e-06 0.31
CHIA_HUMAN CHIA Acidic mammalian chitinase 9.348e-06 0.30

Memantine

NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.508e-07 1.00
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 0.04154 1.00
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 0.1267 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
M2_I000F M Matrix protein 2 8.087e-23 0.45
M2_I72A8 M Matrix protein 2 3.338e-07 0.45

Tioconazole

CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 6.871e-07 1.00
CP121_MYCTU cyp121 Mycocyclosin synthase 1.141e-56 0.71
CP11A_RAT Cyp11a1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.494e-51 0.28
CP7A1_RAT Cyp7a1 Cytochrome P450 7A1 1.494e-51 0.28
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 2.025e-46 0.56
THAS_RAT Tbxas1 Thromboxane-A synthase 4.157e-39 0.37
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 2.622e-36 0.71
CP3A5_HUMAN CYP3A5 Cytochrome P450 3A5 1.522e-35 0.28
HMOX1_RAT Hmox1 Heme oxygenase 1 1.665e-31 0.37
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 8.627e-31 0.38
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 8.148e-29 0.38
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 5.001e-28 0.71
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 1.627e-25 0.28
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 8.319e-24 0.38
CP21A_HUMAN CYP21A2 Steroid 21-hydroxylase 1.165e-23 0.29
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.149e-21 0.71
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 1.337e-18 0.71
HMOX2_RAT Hmox2 Heme oxygenase 2 1.528e-18 0.37
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.853e-18 0.28
CPXA_PSEPU camC Camphor 5-monooxygenase 1.332e-15 0.30
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 3.886e-15 0.71
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.651e-13 0.36
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 3.703e-12 0.33
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.347e-10 0.36
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 1.675e-09 0.71
CP19A_HUMAN CYP19A1 Aromatase 5.759e-09 0.50
Q690N0_BOVIN PGR Progesterone receptor 1.146e-08 0.71
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.619e-08 0.71
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 6.997e-07 0.36
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 3.104e-06 0.38
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.652e-06 0.28
Q8IL32_PLAF7 Heat shock protein 90, putative 8.519e-06 0.78

Levobupivacaine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 6.945e-07 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.8363 1.00
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 3.364e-119 0.43
KCNQ1_HUMAN KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.701e-59 0.34
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 1.632e-53 0.36
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 1.914e-53 0.32
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 8.283e-48 0.30
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 3.059e-43 0.37
PAG_BACAN pagA Protective antigen 3.897e-43 0.32
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 6.023e-42 0.31
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 9.56e-39 0.35
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 1.947e-38 0.30
PPCE_PIG PREP Prolyl endopeptidase 1.03e-36 0.32
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 1.179e-34 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.001e-29 0.42
OPRX_MOUSE Oprl1 Nociceptin receptor 1.053e-29 0.37
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.171e-26 0.36
PPCE_BOVIN PREP Prolyl endopeptidase 3.393e-26 0.29
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 3.138e-25 0.31
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.384e-24 0.36
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 2.883e-24 0.62
KCNQ5_HUMAN KCNQ5 Potassium voltage-gated channel subfamily KQT member 5 7.498e-24 0.29
GLUPH_PLAF7 Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase 1.069e-23 0.29
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 1.288e-23 0.39
CHLE_MOUSE Bche Cholinesterase 1.673e-23 0.29
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 5.888e-22 0.34
O96526_LEIMA CRK3 Cdc2-related kinase 4.191e-19 0.29
CNR2_HUMAN CNR2 Cannabinoid receptor 2 8.797e-19 0.40
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 1.753e-18 0.29
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 5.286e-17 0.31
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.11e-15 0.30
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 2.887e-15 0.33
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 4.996e-15 0.32
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.021e-14 0.35
ACES_MOUSE Ache Acetylcholinesterase 2.032e-14 0.33
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 2.098e-14 0.34
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 6.384e-14 0.38
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.173e-13 0.39
Q9BRH5_HUMAN DGAT1 DGAT1 protein 6.344e-13 0.29
PPCE_RAT Prep Prolyl endopeptidase 1.197e-12 0.31
AA2BR_RAT Adora2b Adenosine receptor A2b 1.446e-12 0.29
DRD2_RAT Drd2 D(2) dopamine receptor 1.757e-12 0.41
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 4.251e-12 0.30
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 4.251e-12 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.883e-11 0.38
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 3.122e-11 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 4.806e-11 0.34
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 5.24e-11 0.30
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 7.435e-11 0.32
PPCE_MOUSE Prep Prolyl endopeptidase 1.105e-10 0.29
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.217e-10 0.36
TRY3_HUMAN PRSS3 Trypsin-3 1.675e-10 0.28
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.932e-10 0.35
OPRM_RAT Oprm1 Mu-type opioid receptor 2.826e-10 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.212e-10 0.32
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 5.051e-10 0.31
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.406e-09 0.32
OX2R_HUMAN HCRTR2 Orexin receptor type 2 1.483e-09 0.35
LEF_BACAN lef Lethal factor 1.507e-09 0.32
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.26e-09 0.31
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 3.618e-09 0.31
CNR2_RAT Cnr2 Cannabinoid receptor 2 4.306e-09 0.32
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 4.757e-09 0.41
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 5.362e-09 0.30
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 1.361e-08 0.29
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.42e-08 0.35
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.721e-08 0.35
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.765e-08 0.39
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 2.54e-08 0.31
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 3.024e-08 0.32
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 3.574e-08 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 4.216e-08 0.38
CNR1_HUMAN CNR1 Cannabinoid receptor 1 4.625e-08 0.39
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 7.48e-08 0.38
CNR1_RAT Cnr1 Cannabinoid receptor 1 8.389e-08 0.32
Q865E1_MACMU HRH3 Histamine receptor H3 1.065e-07 0.29
REV1_HUMAN REV1 DNA repair protein REV1 1.162e-07 0.28
OPRD_RAT Oprd1 Delta-type opioid receptor 2.883e-07 0.33
SPHK2_HUMAN SPHK2 Sphingosine kinase 2 3.098e-07 0.32
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 3.266e-07 0.31
MMP7_HUMAN MMP7 Matrilysin 6.891e-07 0.32
PRIO_MESAU PRNP Major prion protein 7.167e-07 0.32
TERT_HUMAN TERT Telomerase reverse transcriptase 8.486e-07 0.33
LUXR_ALIFS luxR Transcriptional activator protein LuxR 9.067e-07 0.28
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.173e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 1.27e-06 0.33
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.62e-06 0.31
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.827e-06 0.40
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.078e-06 0.34
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.509e-06 0.32
ITA4_HUMAN ITGA4 Integrin alpha-4 2.51e-06 0.34
PANC_MYCTU panC Pantothenate synthetase 2.533e-06 0.30
CATK_HUMAN CTSK Cathepsin K 2.689e-06 0.40
LCK_HUMAN LCK Tyrosine-protein kinase Lck 3.134e-06 0.36
LDLR_HUMAN LDLR Low-density lipoprotein receptor 3.409e-06 0.28
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 3.741e-06 0.30
CCR5_MACFA CCR5 C-C chemokine receptor type 5 4.596e-06 0.29
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 5.98e-06 0.33
CPNS1_PIG CAPNS1 Calpain small subunit 1 6.015e-06 0.31
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 6.575e-06 0.32
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 7.112e-06 0.29
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 8.028e-06 0.31
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 8.069e-06 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.092e-06 0.36
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 8.855e-06 0.33
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 9.479e-06 0.34

Edrophonium

ACES_BOVIN ACHE Acetylcholinesterase 1.589e-06 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.004097 1.00
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.527e-34 0.33
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 1.778e-21 0.34
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 9.803e-19 0.30
G3HDX1_CRIGR Alpha-1B adrenergic receptor 6.876e-18 0.34
5HT5A_RAT Htr5a 5-hydroxytryptamine receptor 5A 1.033e-17 0.34
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.11e-16 0.38
Q2PCB5_DICLA ca Carbonic anhydrase 5.551e-16 0.44
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.599e-14 0.37
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 8.649e-14 0.37
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 2.335e-11 0.33
PPO1_AGABI PPO1 Polyphenol oxidase 1 1.645e-09 0.30
SPRE_HUMAN SPR Sepiapterin reductase 1.106e-08 0.33
CHLE_MOUSE Bche Cholinesterase 2.434e-08 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.631e-07 0.29
O49150_SOLTU Lipoxygenase 8.09e-06 0.28

Frovatriptan

5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 3.181e-06 1.00
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.141e-05 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.003529 1.00
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 2.736e-78 0.48
RB_HUMAN RB1 Retinoblastoma-associated protein 1.238e-61 0.39
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 4.087e-56 0.36
NNMT_MOUSE Nnmt Nicotinamide N-methyltransferase 2.281e-40 0.32
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 1.736e-25 0.44
GPVI_HUMAN GP6 Platelet glycoprotein VI 2.158e-24 0.30
FAAH2_HUMAN FAAH2 Fatty-acid amide hydrolase 2 2.847e-23 0.29
HST2_YEAST HST2 NAD-dependent protein deacetylase HST2 1.242e-22 0.36
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.367e-21 0.33
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 1.11e-16 0.32
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 9.215e-15 0.44
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 4.735e-13 0.32
TYRO_MOUSE Tyr Tyrosinase 1.88e-12 0.30
CCNC_HUMAN CCNC Cyclin-C 3.078e-11 0.38
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.039e-10 0.35
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.049e-10 0.30
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 4.047e-10 0.39
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.231e-09 0.34
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1.386e-09 0.39
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 5.494e-09 0.32
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.496e-08 0.34
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 6.86e-08 0.34
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 1.508e-07 0.29
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 1.663e-07 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 3.083e-07 0.28
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 3.74e-07 0.38
MTR1B_CHICK Melatonin receptor type 1B 4.339e-07 0.29
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.148e-06 0.34
GRM1_RAT Grm1 Metabotropic glutamate receptor 1 3.894e-06 0.36

Benzylpenicillin

STRP_STRP1 ska Streptokinase A 1.076e-05 1.00
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 0.0001565 1.00
O60989_PLAVI Aspartic protease PM4 3.022e-68 0.29
BLAC_BACLI penP Beta-lactamase 1.184e-58 0.32
BLAB_BACCE Metallo-beta-lactamase type 2 1.212e-57 0.51
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 1.297e-48 0.32
A1E3K9_ECOLX blaSCO-1 Beta-lactamase 2.919e-48 0.32
A8RR46_BACCS bcl1 Beta-lactamase 2.919e-48 0.32
D2SSQ3_PSEAI Beta-lactamase 2.919e-48 0.32
Q3SAW3_PSEAI bla(BEL1) Beta-lactamase 2.919e-48 0.32
BLA1_KLEPN bla Beta-lactamase SHV-1 2.601e-47 0.31
AMPC_CITFR ampC Beta-lactamase 1.753e-46 0.31
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 6.892e-42 0.52
D5HSX5_9GAMM blaPER-6 Beta-lactamase 1.841e-40 0.32
Q0VTR6_ACIPI adc-14 Beta-lactamase 1.841e-40 0.32
Q0VTR8_ACIPI adc-16 Beta-lactamase 1.841e-40 0.32
Q7X575_ECOLX SHV-11 Beta-lactamase 1.841e-40 0.32
Q53729_STAAU PBP2 Penicillin-binding protein 2 3.824e-40 0.32
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 4.823e-39 0.39
BLA5_KLEPN bla Beta-lactamase SHV-5 5.748e-39 0.31
NEP_RAT Mme Neprilysin 3.544e-38 0.33
A2RP81_CITFR blaPER-2 Beta-lactamase 2.799e-37 0.56
D1MIX9_PSEAI blaGES-13 Beta-lactamase 3.286e-37 0.32
Q9Y006_PLAFA hap HAP protein 9.406e-37 0.29
A0ZX81_KLEPN blaSHV-72 Beta-lactamase 7.101e-36 0.28
A4KCT8_9ENTR BlaGIL-1 Beta-lactamase 7.101e-36 0.28
AMPC_MORMO ampC Beta-lactamase 7.101e-36 0.28
B8R6A5_9BURK penB1 Beta-lactamase 7.101e-36 0.28
BLKPC_KLEPN bla Carbapenem-hydrolyzing beta-lactamase KPC 7.101e-36 0.28
BLO1_ECOLX bla Beta-lactamase OXA-1 7.101e-36 0.28
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 7.101e-36 0.28
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 7.101e-36 0.28
Q2XPY6_SALET blaCTX-M-53 Beta-lactamase 7.101e-36 0.28
Q50H31_BRAPL oxa-63 Class D beta-lactamase 7.101e-36 0.28
Q670S6_PSELU Beta-lactamase 7.101e-36 0.28
Q6GWS8_ECOLX blaTEM-125 Beta-lactamase 7.101e-36 0.28
Q6JP75_SERFO Beta-lactamase 7.101e-36 0.28
Q9EXV5_ECOLX blaUOE-1 Beta-lactamase 7.101e-36 0.28
BLAC_STAAU blaZ Beta-lactamase 2.074e-35 0.42
Q3S5C3_SALNE sugE Efflux transporter 2.547e-32 0.52
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.547e-32 0.52
AMPC_ECOLI ampC Beta-lactamase 1.565e-28 0.52
ACE_RAT Ace Angiotensin-converting enzyme 1.864e-27 0.33
TRAR_RHIRD traR Transcriptional activator protein TraR 4.145e-27 0.37
PLM2_PLAFA Plasmepsin-2 1.061e-24 0.31
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 1.038e-23 0.30
PPME1_HUMAN PPME1 Protein phosphatase methylesterase 1 1.239e-23 0.29
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 7.991e-23 0.33
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 3.271e-20 0.34
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 9.185e-20 0.32
ACE_HUMAN ACE Angiotensin-converting enzyme 2.28e-18 0.32
RORG_HUMAN RORC Nuclear receptor ROR-gamma 3.041e-18 0.34
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.767e-18 0.38
Q9IP65_HCMV US28 G protein-coupled receptor 1.015e-17 0.34
LASR_PSEAE lasR Transcriptional activator protein LasR 1.044e-17 0.37
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 2.813e-17 0.35
ACE_RABIT ACE Angiotensin-converting enzyme 1.443e-15 0.32
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.443e-15 0.35
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 1.776e-15 0.32
Q72874_9HIV1 pol Pol polyprotein 2.22e-15 0.56
LUXR_ALIFS luxR Transcriptional activator protein LuxR 2.554e-14 0.35
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 5.584e-14 0.30
ISPT_STRPN uppS Isoprenyl transferase 2.289e-13 0.29
CHIB1_ASPFM chiB1 Endochitinase B1 3.922e-13 0.29
Q46991_ENTCL imiA Beta-lactamase 4.846e-13 0.28
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.193e-12 0.34
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.624e-12 0.34
THRB_RAT F2 Prothrombin 1.861e-12 0.30
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 2.492e-12 0.33
IL6RB_HUMAN IL6ST Interleukin-6 receptor subunit beta 3.144e-12 0.30
BLAB_BACFG ccrA Metallo-beta-lactamase type 2 3.526e-12 0.30
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 4.931e-12 0.32
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 1.303e-11 0.31
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 5.041e-11 0.35
AMPC_PSEAE ampC Beta-lactamase 1.013e-10 0.30
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.419e-10 0.29
BLA1_ECOLX bla Beta-lactamase SHV-1 1.484e-10 0.32
CATL1_RAT Ctsl Cathepsin L1 1.659e-10 0.33
MGLL_RAT Mgll Monoglyceride lipase 2.294e-10 0.29
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 2.739e-10 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.589e-10 0.34
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 5.539e-10 0.30
CHIA_SERMA chiA Chitinase A 7.541e-10 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.185e-09 0.32
NEP_HUMAN MME Neprilysin 1.273e-09 0.31
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.319e-09 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.324e-09 0.29
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.37e-09 0.30
AMPC_ENTCL ampC Beta-lactamase 1.449e-09 0.33
ELNE_HUMAN ELANE Neutrophil elastase 1.596e-09 0.59
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.089e-09 0.31
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 2.256e-09 0.29
FUCO_HUMAN FUCA1 Tissue alpha-L-fucosidase 2.753e-09 0.31
PRO_HTL1A gag-pro Gag-Pro polyprotein 3.315e-09 0.28
B4URF0_I33A0 Neuraminidase 6.706e-09 0.35
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 2.267e-08 0.30
KLK6_HUMAN KLK6 Kallikrein-6 2.696e-08 0.29
AMP1_PLAFQ M1 family aminopeptidase 4.466e-08 0.29
TRY1_HUMAN PRSS1 Trypsin-1 5.242e-08 0.30
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 9.862e-08 0.33
Q38C41_TRYB2 Phosphotransferase 1.067e-07 0.33
DEF_STAAM def Peptide deformylase 1.391e-07 0.30
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.968e-07 0.35
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 5.13e-07 0.28
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.01e-06 0.30
THRB_HUMAN F2 Prothrombin 1.419e-06 0.32
Q9YQ12_9HIV1 protease Protease 1.889e-06 0.31
OPRX_CAVPO OPRL1 Nociceptin receptor 2.369e-06 0.29
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 2.488e-06 0.30
Q6W9J1_ENTCL blaTEM-1 Beta-lactamase 3.133e-06 0.28
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 4.926e-06 0.32
H9B8T9_CAPHI CTSB Cathepsin B 6.119e-06 0.35
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.552e-06 0.29
GPR39_HUMAN GPR39 G-protein coupled receptor 39 9.622e-06 0.32
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 9.954e-06 0.31

Acetophenazine

ANDR_RAT Ar Androgen receptor 4.41e-05 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 5.807e-143 0.71
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.247e-74 0.43
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.852e-71 0.65
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.051e-69 0.33
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 7.6e-60 0.32
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 1.355e-57 0.30
PRIO_MOUSE Prnp Major prion protein 4.562e-54 0.43
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.557e-52 0.65
DRD1_PIG DRD1 D(1A) dopamine receptor 1.856e-52 0.34
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.335e-51 0.71
TYTR_TRYCR TPR Trypanothione reductase 2.916e-47 0.43
DRD5_RAT Drd5 D(1B) dopamine receptor 8.21e-47 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.057e-44 0.43
LYSC1_RAT Lyz1 Lysozyme C-1 3.904e-44 0.55
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.124e-44 0.65
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.362e-43 0.65
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.289e-43 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 4.374e-39 0.55
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.827e-37 0.29
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.46e-37 0.71
CALM_BOVIN CALM Calmodulin 8.647e-35 0.55
BGLR_RAT Gusb Beta-glucuronidase 4.812e-34 0.55
EBPL_HUMAN EBPL Emopamil-binding protein-like 4.812e-34 0.55
DRD3_RAT Drd3 D(3) dopamine receptor 1.347e-33 0.34
NOX1_HUMAN NOX1 NADPH oxidase 1 8.273e-31 0.56
CHLE_HUMAN BCHE Cholinesterase 6.789e-28 0.41
HRH1_HUMAN HRH1 Histamine H1 receptor 6.85e-28 0.65
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.463e-26 0.29
CALM1_HUMAN CALM1 Calmodulin-1 4.57e-26 0.55
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.978e-24 0.65
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.239e-20 0.65
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.425e-20 0.40
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.868e-20 0.65
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 6.698e-20 0.36
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.692e-19 0.30
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.396e-18 0.65
DRD4_RAT Drd4 D(4) dopamine receptor 1.986e-18 0.32
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.715e-18 0.65
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.18e-17 0.36
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.11e-16 0.65
ERG2_YEAST ERG2 C-8 sterol isomerase 1.11e-16 0.55
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.22e-16 0.36
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 2.22e-16 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.331e-16 0.65
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.772e-16 0.65
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.772e-16 0.59
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 8.882e-16 0.30
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.44e-15 0.32
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.243e-14 0.65
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.642e-14 0.55
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.186e-14 0.78
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 4.197e-14 0.30
DRD1_RAT Drd1 D(1A) dopamine receptor 6.184e-14 0.43
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 1.751e-13 0.37
HRH2_HUMAN HRH2 Histamine H2 receptor 2.214e-13 0.65
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 3.372e-13 0.30
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 1.385e-12 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.983e-12 0.65
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 2.393e-12 0.31
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 2.443e-12 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.876e-12 0.65
CHLE_HORSE BCHE Cholinesterase 7.721e-12 0.51
DRD2_BOVIN DRD2 D(2) dopamine receptor 8.775e-12 0.43
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.059e-11 0.32
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.444e-11 0.29
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.633e-11 0.36
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 4.884e-11 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 6.574e-11 0.31
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.657e-10 0.32
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 2.303e-10 0.37
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 2.367e-10 0.31
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 6.439e-10 0.29
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.254e-09 0.31
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.284e-09 0.65
HRH1_RAT Hrh1 Histamine H1 receptor 1.09e-08 0.42
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.126e-08 0.65
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.17e-08 0.39
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.352e-08 0.65
PRIO_HUMAN PRNP Major prion protein 2.656e-08 0.66
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.866e-08 0.65
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 5.438e-08 0.43
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.905e-08 0.65
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 9.041e-08 0.65
DEF_STAAM def Peptide deformylase 9.226e-08 0.31
ACES_ELEEL ache Acetylcholinesterase 9.842e-08 0.36
WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.088e-07 0.55
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.479e-07 0.55
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.689e-07 0.65
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.995e-07 0.29
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.984e-07 0.65
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 6.994e-07 0.30
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.281e-06 0.38
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.846e-06 0.50
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.846e-06 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.91e-06 0.43
ACES_HUMAN ACHE Acetylcholinesterase 3.135e-06 0.40
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.143e-06 0.32
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.823e-06 0.44
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 4.352e-06 0.37
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 7.946e-06 0.32
HRH1_CAVPO HRH1 Histamine H1 receptor 9.131e-06 0.43
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 9.673e-06 0.32

Cytarabine

NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 7.735e-05 1.00
LMP1_EBVB9 LMP1 Latent membrane protein 1 0.0002068 1.00
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 3.483e-213 0.46
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 5.452e-204 0.55
ADOK_MYCTO adoK Adenosine kinase 2.579e-170 0.47
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 5.23e-158 0.49
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.125e-150 0.41
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 2.934e-145 0.43
ADK_TOXGO AK Adenosine kinase 2.701e-137 0.45
AA1R_RAT Adora1 Adenosine receptor A1 1.648e-129 0.49
CDD_MOUSE Cda Cytidine deaminase 1.287e-121 0.60
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 3.151e-118 0.35
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 3.948e-104 0.38
CDD_HUMAN CDA Cytidine deaminase 4.354e-102 0.60
AA1R_CHICK ADORA1 Adenosine receptor A1 9.841e-100 0.39
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 1.747e-90 0.35
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 5.255e-86 0.39
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 7.825e-85 0.71
AA2AR_RAT Adora2a Adenosine receptor A2a 1.589e-83 0.48
ADK_HUMAN ADK Adenosine kinase 2.657e-81 0.53
AA1R_CAVPO ADORA1 Adenosine receptor A1 7.951e-75 0.49
KITH_VZVD TK Thymidine kinase 2.936e-74 0.40
P2RY1_RAT P2ry1 P2Y purinoceptor 1 2.333e-71 0.33
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.878e-70 0.97
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 1.994e-70 0.31
PUR6_CHICK AIRC Multifunctional protein ADE2 6.705e-70 0.35
ISPE_ECOLI ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1.447e-64 0.52
AA3R_RABIT ADORA3 Adenosine receptor A3 1.891e-63 0.31
P2RY4_RAT P2ry4 P2Y purinoceptor 4 9.485e-62 0.36
AA1R_RABIT ADORA1 Adenosine receptor A1 3.81e-61 0.31
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 3.004e-60 0.54
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 6.876e-59 0.46
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.139e-58 0.45
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 2.392e-58 0.32
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 6.04e-58 0.43
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.913e-55 0.44
KITH_VZVO TK Thymidine kinase 3.161e-53 0.37
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 3.188e-51 0.30
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.238e-49 0.30
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 3.57e-49 0.33
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 3.969e-49 0.33
NADK_HUMAN NADK NAD kinase 1.053e-48 0.31
ADA_MOUSE Ada Adenosine deaminase 2.758e-48 0.60
AA1R_HUMAN ADORA1 Adenosine receptor A1 2.984e-48 0.45
ENTE_ECOLI entE Enterobactin synthase component E 1.425e-46 0.29
POLG_POL1M Genome polyprotein 9.43e-46 0.36
P2RY2_RAT P2ry2 P2Y purinoceptor 2 2.199e-45 0.36
B4EH87_BURCJ Lectin 2.267e-45 0.33
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.657e-45 0.32
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 3.054e-45 0.28
C3SIU2_ECOLX metJ Met repressor 5.091e-43 0.31
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 5.166e-42 0.33
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 5.166e-42 0.33
NADK1_LISMF nadK1 NAD kinase 1 5.166e-42 0.33
NADK_STAAC nadK NAD kinase 5.166e-42 0.33
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 9.794e-42 0.35
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 9.519e-41 0.32
WALK_STAAU walK Sensor protein kinase WalK 9.519e-41 0.32
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.464e-40 0.32
GGTA1_BOVIN GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 1.972e-40 0.32
Q8KHJ3_NEIME lgtC Alpha 1,4 galactosyltransferase 1.972e-40 0.32
Q8T6J6_PLAFA ompdc Orotidine 5'-monophosphate decarboxylase 5.881e-40 0.32
P2RX5_RAT P2rx5 P2X purinoceptor 5 9.213e-40 0.33
P2RX6_RAT P2rx6 P2X purinoceptor 6 9.213e-40 0.33
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 3.809e-39 0.32
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 7.445e-39 0.45
AA3R_RAT Adora3 Adenosine receptor A3 1.743e-38 0.45
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 6.694e-38 0.30
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 7.11e-38 0.33
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 1.023e-37 0.30
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 1.023e-37 0.30
SYS_ECOLI serS Serine--tRNA ligase 7.142e-37 0.29
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.187e-36 0.33
S28A2_RAT Slc28a2 Sodium/nucleoside cotransporter 2 1.332e-36 0.29
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 6.705e-36 0.28
KITH_RAT Tk1 Thymidine kinase, cytosolic 1.852e-35 0.29
RASK_HUMAN KRAS GTPase KRas 2.339e-35 0.29
TOP1_HUMAN TOP1 DNA topoisomerase 1 1.443e-34 0.35
ADA_BOVIN ADA Adenosine deaminase 7.278e-33 0.47
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 7.496e-33 0.35
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.19e-32 0.45
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 8.221e-30 0.29
P2RY6_RAT P2ry6 P2Y purinoceptor 6 1.109e-29 0.37
SPEE_HUMAN SRM Spermidine synthase 2.535e-29 0.29
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 1.079e-28 0.35
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 1.775e-27 0.32
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 2.798e-25 0.33
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 3.865e-25 0.31
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 3.865e-25 0.31
SAHH_HUMAN AHCY Adenosylhomocysteinase 4.086e-25 0.47
ADA_HUMAN ADA Adenosine deaminase 5.663e-25 0.47
AMPD1_RABIT AMPD1 AMP deaminase 1 6.731e-25 0.31
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 9.841e-25 0.30
DPOLB_HUMAN POLB DNA polymerase beta 1.478e-24 0.44
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 2.64e-24 0.32
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 6.243e-24 0.29
PQSA_PSEAE pqsA Anthranilate--CoA ligase 2e-23 0.29
SPSY_HUMAN SMS Spermine synthase 2.847e-23 0.29
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 5.518e-23 0.28
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 7.318e-23 0.28
MRAY_ECOLI mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 3.88e-22 0.35
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 2.722e-21 0.33
A3RLP8_CHV1 UL23 Thymidine kinase 1.202e-20 0.29
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.995e-20 0.37
GLCM_BOVIN GBA Lysosomal acid glucosylceramidase 3.801e-20 0.32
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 3.97e-20 0.44
KITH_HUMAN TK1 Thymidine kinase, cytosolic 4.068e-20 0.38
Q4VQ11_PIG Adenosine receptor A1 1.858e-19 0.39
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 1.523e-18 0.29
P2RX4_RAT P2rx4 P2X purinoceptor 4 1.704e-18 0.33
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 3.299e-18 0.45
MRAY_BACSU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 3.809e-18 0.29
Q99MI5_RAT LOC100912604 Spermidine synthase 4.879e-18 0.29
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 6.375e-18 0.28
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 6.375e-18 0.28
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 8.104e-18 0.28
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1.976e-17 0.30
P2RX1_RAT P2rx1 P2X purinoceptor 1 2.201e-17 0.35
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 3.113e-17 0.35
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 3.774e-17 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.331e-16 0.34
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 8.882e-16 0.30
V5TFZ2_9FLAV Nonstructural protein 5 1.11e-15 0.43
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 2.22e-15 0.40
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.554e-15 0.53
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.887e-15 0.33
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 5.551e-15 0.28
O39930_9HEPC NS5b RNA-directed RNA polymerase 6.106e-15 0.45
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 9.548e-15 0.40
P2RY2_MOUSE P2ry2 P2Y purinoceptor 2 1.321e-14 0.36
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 2.165e-14 0.33
CD69_HUMAN CD69 Early activation antigen CD69 3.12e-14 0.35
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.12e-14 0.35
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 7.383e-14 0.42
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 1.003e-13 0.64
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1.141e-13 0.37
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 1.308e-13 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.011e-12 0.39
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 1.4e-12 0.31
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 1.88e-12 0.30
SAHH_RAT Ahcy Adenosylhomocysteinase 4.323e-12 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 5.121e-12 0.40
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.129e-11 0.34
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.322e-11 0.39
CCNK_HUMAN CCNK Cyclin-K 2.506e-11 0.30
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 3.989e-11 0.30
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 5.816e-11 0.34
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 7.356e-11 0.34
ADCY2_RAT Adcy2 Adenylate cyclase type 2 1.336e-10 0.28
ADK_RAT Adk Adenosine kinase 7.982e-10 0.35
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 8.149e-10 0.31
AA1R_BOVIN ADORA1 Adenosine receptor A1 8.882e-10 0.45
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.371e-09 0.40
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 1.399e-09 0.55
DCPS_HUMAN DCPS m7GpppX diphosphatase 3.999e-09 0.35
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 5.941e-09 0.34
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 1.026e-08 0.40
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.07e-08 0.41
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.258e-08 0.43
KITH_HHV1S TK Thymidine kinase 1.374e-08 0.40
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.536e-08 0.28
P2RX2_RAT P2rx2 P2X purinoceptor 2 1.543e-08 0.33
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 1.867e-08 0.30
OGA_HUMAN OGA Protein O-GlcNAcase 2.515e-08 0.30
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.742e-08 0.40
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 4.179e-08 0.28
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 5.884e-08 0.31
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 5.984e-08 0.43
TYPH_HUMAN TYMP Thymidine phosphorylase 1.244e-07 0.38
PNPH_HUMAN PNP Purine nucleoside phosphorylase 1.308e-07 0.45
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 1.714e-07 0.46
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 2.617e-07 0.28
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 4.107e-07 0.37
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 4.559e-07 0.29
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 5.06e-07 0.30
INMT_HUMAN INMT Indolethylamine N-methyltransferase 5.06e-07 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.533e-07 0.28
5NTD_RAT Nt5e 5'-nucleotidase 6.744e-07 0.32
5NTD_HUMAN NT5E 5'-nucleotidase 9.234e-07 0.32
LEG9_HUMAN LGALS9 Galectin-9 9.412e-07 0.30
P2Y12_RAT P2ry12 P2Y purinoceptor 12 1.62e-06 0.33
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 1.851e-06 0.32
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 2.064e-06 0.30
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.242e-06 0.32
ADCY5_RAT Adcy5 Adenylate cyclase type 5 3.073e-06 0.30
ENPL_CANLF HSP90B1 Endoplasmin 6.365e-06 0.32
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.551e-06 0.32
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 9.329e-06 0.31

Abacavir

Q72547_9HIV1 pol Reverse transcriptase/RNaseH 0.0002722 1.00
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 0.09494 1.00
Q4VQ11_PIG Adenosine receptor A1 4.883e-95 0.42
AA1R_RAT Adora1 Adenosine receptor A1 1.318e-92 0.57
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 5.058e-72 0.45
SAHH_PLAF7 Adenosylhomocysteinase 2.085e-62 0.44
AA2AR_RAT Adora2a Adenosine receptor A2a 1.526e-55 0.45
AA1R_CAVPO ADORA1 Adenosine receptor A1 5.605e-52 0.42
AA3R_HUMAN ADORA3 Adenosine receptor A3 7.554e-50 0.45
AA1R_HUMAN ADORA1 Adenosine receptor A1 4.601e-48 0.45
AA1R_CHICK ADORA1 Adenosine receptor A1 1.601e-43 0.38
ADCY2_RAT Adcy2 Adenylate cyclase type 2 2.215e-38 0.39
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 7.73e-31 0.45
AA3R_RAT Adora3 Adenosine receptor A3 1.334e-29 0.42
ADA_MOUSE Ada Adenosine deaminase 5.245e-27 0.33
ADCY5_RAT Adcy5 Adenylate cyclase type 5 3.168e-25 0.38
AA1R_BOVIN ADORA1 Adenosine receptor A1 7.912e-25 0.42
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 1.302e-21 0.39
SAHH_HUMAN AHCY Adenosylhomocysteinase 2.345e-21 0.34
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 3.536e-20 0.38
ADA_BOVIN ADA Adenosine deaminase 4.39e-19 0.36
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 1.372e-18 0.29
C3SIU2_ECOLX metJ Met repressor 2.22e-16 0.30
Q6R7Z5_9TRYP Cathepsin B-like cysteine protease 3.331e-16 0.40
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 5.707e-14 0.37
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.207e-13 0.38
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.953e-12 0.45
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 4.241e-12 0.36
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 4.351e-12 0.34
SAHH_MOUSE Ahcy Adenosylhomocysteinase 9.395e-12 0.32
STAT3_MOUSE Stat3 Signal transducer and activator of transcription 3 9.99e-12 0.32
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 3.753e-11 0.36
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 3.753e-11 0.36
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.061e-10 0.38
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 1.295e-10 0.28
DPOLB_HUMAN POLB DNA polymerase beta 5.962e-10 0.31
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 2.801e-08 0.33
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 3.646e-08 0.29
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 1.244e-07 0.38
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 5.278e-07 0.28
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 9.968e-07 0.38
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 1.108e-06 0.36
5NTD_HUMAN NT5E 5'-nucleotidase 1.263e-06 0.32
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1.717e-06 0.31
ADA_HUMAN ADA Adenosine deaminase 1.761e-06 0.29
AA3R_RABIT ADORA3 Adenosine receptor A3 3.531e-06 0.28
AA1R_RABIT ADORA1 Adenosine receptor A1 5.652e-06 0.28
AA1R_MOUSE Adora1 Adenosine receptor A1 9.107e-06 0.42

Amlexanox

GPR35_HUMAN GPR35 G-protein coupled receptor 35 0.0008578 1.00
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 0.03813 1.00
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 0.05133 1.00
UCHL1_HUMAN UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 2.741e-45 0.30
Q06347_9HIV2 reverse transcriptase Reverse transcriptase 3.568e-41 0.33
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 5.471e-18 0.29
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.331e-16 0.33
CAH3_HUMAN CA3 Carbonic anhydrase 3 7.917e-13 0.32
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.586e-12 0.33
RNH1_HUMAN RNASEH1 Ribonuclease H1 3.836e-11 0.33
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.476e-06 0.33
PTPRF_HUMAN PTPRF Receptor-type tyrosine-protein phosphatase F 2.049e-06 0.32
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 2.226e-06 0.31
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 3.462e-06 0.33

Oxaprozin

PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 0.0009126 1.00
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 3.155e-54 0.43
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 2.122e-41 0.37
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 9.57e-40 0.37
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 6.214e-38 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 1.555e-33 0.33
FFAR1_RAT Ffar1 Free fatty acid receptor 1 1.948e-27 0.33
LT4R2_HUMAN LTB4R2 Leukotriene B4 receptor 2 3.252e-27 0.31
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.274e-25 0.35
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 2.08e-24 0.33
BLAB_SERMA Metallo-beta-lactamase type 2 1.444e-23 0.29
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 2.674e-23 0.50
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.886e-23 0.35
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 4.898e-23 0.35
FAAH2_HUMAN FAAH2 Fatty-acid amide hydrolase 2 7.04e-23 0.28
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 8.65e-23 0.40
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 1.579e-20 0.40
MGLL_RAT Mgll Monoglyceride lipase 4.739e-20 0.31
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 5.429e-20 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 6.095e-19 0.35
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 9.444e-19 0.44
GBRA1_MOUSE Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.126e-18 0.30
NEP_RAT Mme Neprilysin 2.142e-18 0.33
PI2R_HUMAN PTGIR Prostacyclin receptor 5.311e-18 0.39
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 6.9e-18 0.33
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 8.907e-18 0.37
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 2.22e-16 0.50
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.22e-16 0.31
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 7.772e-16 0.30
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 7.381e-13 0.33
REST_BORBU resT Telomere resolvase ResT 2.757e-12 0.30
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.077e-11 0.33
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.555e-11 0.35
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.856e-11 0.41
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 5.554e-11 0.33
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 8.244e-11 0.33
TSPO_RAT Tspo Translocator protein 2.108e-10 0.32
DPP2_RAT Dpp7 Dipeptidyl peptidase 2 3.022e-10 0.30
MMP10_HUMAN MMP10 Stromelysin-2 1.045e-09 0.31
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 1.713e-09 0.30
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 3.055e-09 0.29
Q962Y6_SCHMA TGR Thioredoxin glutathione reductase 3.984e-09 0.33
MTP_BOVIN MTTP Microsomal triglyceride transfer protein large subunit 7.453e-09 0.37
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 8.14e-09 0.41
ANF_HUMAN NPPA Natriuretic peptides A 3.118e-08 0.29
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.396e-07 0.30
PI2R_RAT Ptgir Prostacyclin receptor 1.396e-07 0.35
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.7e-07 0.33
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 3.059e-07 0.37
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 3.563e-07 0.32
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 4.847e-07 0.30
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 7.054e-07 0.33
LPAR1_RAT Lpar1 Lysophosphatidic acid receptor 1 9.396e-07 0.29
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.473e-06 0.31
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 2.239e-06 0.32
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 2.409e-06 0.29
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 2.798e-06 0.34
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 3.052e-06 0.31
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.572e-06 0.30
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 4.586e-06 0.30
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 4.705e-06 0.33
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 5.06e-06 0.38
AA3R_RAT Adora3 Adenosine receptor A3 5.221e-06 0.31
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 5.734e-06 0.29
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.925e-06 0.35
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 6.402e-06 0.30
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 8.187e-06 0.29
RHOA_HUMAN RHOA Transforming protein RhoA 9.1e-06 0.33

Azlocillin

STRP_STRP1 ska Streptokinase A 0.001039 1.00
Q82134_9DELA prt Protease 1.223e-115 0.31
Q82323_9DELA Protease 1.849e-76 0.30
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 3.143e-69 0.32
PRO_HTL1A gag-pro Gag-Pro polyprotein 8.42e-41 0.31
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 3.392e-34 0.42
A2RP81_CITFR blaPER-2 Beta-lactamase 5.735e-34 0.77
BLAB_BACCE Metallo-beta-lactamase type 2 1.214e-32 0.37
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.172e-30 0.34
Q3S5C3_SALNE sugE Efflux transporter 2.03e-26 0.42
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.03e-26 0.42
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.158e-24 0.30
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 8.603e-22 0.32
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 7.228e-20 0.35
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.11e-16 0.31
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.687e-14 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.941e-12 0.35
AMPC_CITFR ampC Beta-lactamase 8.289e-12 0.29
BLAC_BACLI penP Beta-lactamase 8.289e-12 0.29
CATL1_RAT Ctsl Cathepsin L1 4.615e-11 0.35
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.367e-09 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 6.425e-08 0.30
AMPC_ECOLI ampC Beta-lactamase 4.107e-07 0.39
TF2AA_HUMAN GTF2A1 Transcription initiation factor IIA subunit 1 8.09e-06 0.28

Perhexiline

FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.01089 1.00
GPR55_HUMAN GPR55 G-protein coupled receptor 55 0.02848 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.08099 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.4304 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.5947 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.7812 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1 1.00
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 2.22e-16 0.32
Q6RY99_RAT Tetraspanin 4.393e-11 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.778e-08 0.33
PNMT_BOVIN PNMT Phenylethanolamine N-methyltransferase 2.466e-08 0.30
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.289e-07 0.33
M2_I000F M Matrix protein 2 6.705e-07 0.31

Busulfan

MMP9_HUMAN MMP9 Matrix metalloproteinase-9 0.789 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 8.061e-12 0.48
CAH13_MOUSE Ca13 Carbonic anhydrase 13 5.518e-11 0.48
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 6.192e-06 0.48
CAH6_HUMAN CA6 Carbonic anhydrase 6 9.562e-06 0.48

Praziquantel

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.9921 1.00
Q962Y6_SCHMA TGR Thioredoxin glutathione reductase 8.153e-41 0.54
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 3.784e-38 0.34
A8PUY1_MALGO LIP1, secretory lipase (Family 3) 4.265e-38 0.30
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.768e-27 0.32
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 6.835e-25 0.32
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.486e-23 0.37
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.569e-23 0.30
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.794e-22 0.42
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.659e-21 0.42
PPCE_BOVIN PREP Prolyl endopeptidase 2.765e-18 0.31
CARP2_CANAX SAP2 Candidapepsin-2 6.092e-18 0.29
GPC6A_MOUSE Gprc6a G-protein coupled receptor family C group 6 member A 6.375e-18 0.28
Q1HEC0_RAT Acetyl-Coenzyme A carboxylase 2 8.52e-18 0.28
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 1.11e-16 0.32
PPCE_HUMAN PREP Prolyl endopeptidase 2.22e-16 0.32
VACHT_TETCF Vesicular acetylcholine transporter 1.443e-15 0.40
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.166e-14 0.40
TP53B_HUMAN TP53BP1 TP53-binding protein 1 2.343e-13 0.29
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 2.898e-13 0.32
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.393e-13 0.35
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.014e-13 0.39
PRIO_MESAU PRNP Major prion protein 2.337e-12 0.31
V1AR_RAT Avpr1a Vasopressin V1a receptor 3.034e-12 0.32
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.113e-12 0.39
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 8.604e-12 0.39
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.1e-11 0.35
Q6RY99_RAT Tetraspanin 4.073e-11 0.30
ACE_HUMAN ACE Angiotensin-converting enzyme 5.099e-11 0.31
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.143e-11 0.35
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.587e-10 0.37
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.641e-10 0.40
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 3.886e-10 0.39
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.943e-09 0.34
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.534e-09 0.31
Q5TKS5_STAAU fabI Enoyl-ACP reductase 2.822e-09 0.29
ACHA6_HUMAN CHRNA6 Neuronal acetylcholine receptor subunit alpha-6 4.756e-09 0.35
ACHB3_HUMAN CHRNB3 Neuronal acetylcholine receptor subunit beta-3 4.756e-09 0.35
SEPR_HUMAN FAP Prolyl endopeptidase FAP 6.48e-09 0.32
HRH1_RAT Hrh1 Histamine H1 receptor 1.296e-08 0.35
PPCE_PIG PREP Prolyl endopeptidase 1.681e-08 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 1.702e-08 0.29
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.703e-08 0.28
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 4.239e-08 0.30
PPCE_RAT Prep Prolyl endopeptidase 6.281e-08 0.30
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 7.415e-08 0.38
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.625e-08 0.38
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.336e-07 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.547e-07 0.30
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 5.118e-07 0.39
ACE_RABIT ACE Angiotensin-converting enzyme 5.631e-07 0.32
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 5.847e-07 0.40
THER_BACTH npr Thermolysin 7.908e-07 0.28
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 9.103e-07 0.42
DGAT2_HUMAN DGAT2 Diacylglycerol O-acyltransferase 2 1.452e-06 0.31
MEP50_HUMAN WDR77 Methylosome protein 50 1.611e-06 0.32
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.882e-06 0.32
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.975e-06 0.40
OPRX_HUMAN OPRL1 Nociceptin receptor 1.985e-06 0.38
Q25270_LEIDO beta-tubulin Beta-tubulin 2.849e-06 0.29
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.136e-06 0.29
DRD2_BOVIN DRD2 D(2) dopamine receptor 3.181e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 3.186e-06 0.31
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 4.907e-06 0.37
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 5.895e-06 0.29
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 8.522e-06 0.32
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 9.59e-06 0.32

Melphalan

CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 1.484e-134 0.38
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.515e-75 0.42
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.271e-74 0.39
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 5.137e-65 0.42
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 9.602e-60 0.54
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 4.51e-57 0.39
TY3H_RAT Th Tyrosine 3-monooxygenase 2.106e-55 0.44
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.304e-54 0.30
KYNU_HUMAN KYNU Kynureninase 1.241e-52 0.33
MURI_LACFE murI Glutamate racemase 1.083e-43 0.35
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 6.658e-42 0.38
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 1.381e-38 0.31
GRIA1_MOUSE Gria1 Glutamate receptor 1 1.339e-37 0.32
GLO2_BOVIN HAGH Hydroxyacylglutathione hydrolase, mitochondrial 5.953e-37 0.29
KYNU_RAT Kynu Kynureninase 3.875e-36 0.29
GRIA2_RAT Gria2 Glutamate receptor 2 8.518e-35 0.39
AMPB_RAT Rnpep Aminopeptidase B 1.743e-34 0.32
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 3.635e-32 0.34
NK1R_RAT Tacr1 Substance-P receptor 5.063e-32 0.41
GRIA3_HUMAN GRIA3 Glutamate receptor 3 2.086e-31 0.30
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.627e-31 0.30
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 9.384e-30 0.38
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 1.607e-29 0.37
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 3.323e-29 0.31
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.542e-27 0.32
TY3H_HUMAN TH Tyrosine 3-monooxygenase 1.963e-27 0.44
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.881e-27 0.34
GRIK5_RAT Grik5 Glutamate receptor ionotropic, kainate 5 4.653e-27 0.31
CSK_HUMAN CSK Tyrosine-protein kinase CSK 2.025e-26 0.40
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 6.915e-26 0.30
GRIA1_HUMAN GRIA1 Glutamate receptor 1 1.496e-24 0.35
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 2.683e-24 0.33
GLO2_HUMAN HAGH Hydroxyacylglutathione hydrolase, mitochondrial 8.657e-24 0.29
AMPL_PIG LAP3 Cytosol aminopeptidase 1.02e-23 0.28
AMPB_HUMAN RNPEP Aminopeptidase B 1.256e-23 0.34
B9V8S1_XENLA grik2.L Ionotropic glutamate receptor subunit GluR6(Q) 2.847e-23 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 2.94e-23 0.33
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 7.903e-22 0.35
GRIA3_RAT Gria3 Glutamate receptor 3 2.532e-21 0.33
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 6.654e-21 0.33
LGUL_YEAST GLO1 Lactoylglutathione lyase 2.958e-20 0.28
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.602e-19 0.39
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.126e-18 0.30
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 9.056e-18 0.28
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 9.264e-18 0.35
NEP_MOUSE Mme Neprilysin 1.11e-16 0.37
LY96_HUMAN LY96 Lymphocyte antigen 96 3.331e-16 0.31
GRIA1_RAT Gria1 Glutamate receptor 1 7.772e-16 0.33
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 5.329e-15 0.29
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 7.55e-15 0.33
GRIA4_RAT Gria4 Glutamate receptor 4 7.772e-15 0.29
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 2.209e-14 0.31
SEPR_HUMAN FAP Prolyl endopeptidase FAP 7.649e-14 0.32
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.068e-13 0.35
GRIA2_HUMAN GRIA2 Glutamate receptor 2 2.985e-13 0.35
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 8.741e-13 0.35
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 8.845e-13 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.011e-12 0.35
AMPN_PIG ANPEP Aminopeptidase N 3.175e-12 0.35
GRIA4_HUMAN GRIA4 Glutamate receptor 4 3.691e-12 0.35
RASH_HUMAN HRAS GTPase HRas 4.657e-12 0.31
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 5.257e-12 0.33
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 2.037e-11 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.111e-11 0.33
AMPN_HUMAN ANPEP Aminopeptidase N 1.767e-10 0.34
Q9Z1J7_RAT Slc1a5 Amino acid transporter 1.087e-09 0.28
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.463e-09 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 7.065e-09 0.35
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.106e-08 0.33
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.96e-08 0.29
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.238e-07 0.30
THB_RAT Thrb Thyroid hormone receptor beta 1.277e-07 0.34
ALBU_BOVIN ALB Serum albumin 2.648e-07 0.33
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 3.122e-07 0.32
OPRM_RAT Oprm1 Mu-type opioid receptor 3.634e-07 0.40
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 3.81e-07 0.40
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 4.816e-07 0.33
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 7.646e-07 0.35
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 8.564e-07 0.30
OPRD_RAT Oprd1 Delta-type opioid receptor 9.84e-07 0.40
NEP_HUMAN MME Neprilysin 1.386e-06 0.30
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.823e-06 0.35
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.837e-06 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.938e-06 0.32
OPRX_CAVPO OPRL1 Nociceptin receptor 2.587e-06 0.29
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 7.294e-06 0.30
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 9.591e-06 0.29

Melatonin

MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.377e-314 0.83
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.725e-283 0.76
SYUA_HUMAN SNCA Alpha-synuclein 4.972e-152 0.58
SPRE_HUMAN SPR Sepiapterin reductase 3.358e-120 0.57
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 7.432e-120 0.43
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 4.216e-115 0.68
MTR1B_CHICK Melatonin receptor type 1B 2.986e-95 0.42
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 2.415e-86 0.32
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.575e-84 0.69
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 5.077e-71 0.54
PERM_HUMAN MPO Myeloperoxidase 3.023e-65 0.48
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 2.342e-60 0.53
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.604e-54 0.32
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 4.078e-52 0.33
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.819e-45 0.57
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 3.689e-43 0.36
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.906e-37 0.56
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 4.202e-34 0.45
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.095e-33 0.36
NMBR_HUMAN NMBR Neuromedin-B receptor 1.467e-33 0.41
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 9.732e-32 0.31
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.415e-31 0.36
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.892e-31 0.41
CHLE_HUMAN BCHE Cholinesterase 7.13e-31 0.59
KI20A_HUMAN KIF20A Kinesin-like protein KIF20A 4.992e-30 0.34
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.462e-30 0.71
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 3.276e-29 0.31
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.794e-28 0.41
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 6.038e-28 0.41
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 9.356e-28 0.36
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 9.779e-28 0.45
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.161e-27 0.52
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.824e-26 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 3.01e-26 0.31
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 7.533e-26 0.41
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 8.932e-26 0.55
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.14e-25 0.53
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 2.058e-25 0.52
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.898e-25 0.39
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.697e-25 0.54
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 7.256e-25 0.44
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 7.498e-25 0.44
ACES_HUMAN ACHE Acetylcholinesterase 3.567e-24 0.60
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.953e-24 0.56
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.109e-23 0.33
ACES_BOVIN ACHE Acetylcholinesterase 2.315e-22 0.49
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 2.54e-22 0.55
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.447e-20 0.64
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.979e-20 0.69
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.322e-19 0.31
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.503e-19 0.35
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 3.278e-19 0.31
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.302e-19 0.37
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 5.329e-19 0.30
NK2R_RAT Tacr2 Substance-K receptor 8.99e-19 0.38
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 1.406e-18 0.36
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 9.771e-18 0.28
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.168e-17 0.42
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 1.469e-17 0.40
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.577e-17 0.31
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.482e-17 0.49
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 2.607e-17 0.40
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.911e-17 0.60
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.11e-16 0.42
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.22e-16 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.772e-16 0.35
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 1.665e-15 0.33
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 2.109e-15 0.29
THA_HUMAN THRA Thyroid hormone receptor alpha 3.664e-15 0.36
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 9.326e-15 0.29
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.044e-14 0.31
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.876e-14 0.31
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.898e-14 0.40
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.964e-14 0.56
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 3.586e-14 0.67
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.474e-14 0.62
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 8.671e-14 0.52
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.112e-13 0.40
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.152e-13 0.56
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 3.232e-13 0.52
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 3.773e-13 0.32
DPOL_HHV11 DNA polymerase catalytic subunit 4.846e-13 0.28
DPOL_VZVD DNA polymerase catalytic subunit 4.846e-13 0.28
Q9JN24_ECOLX def Peptide deformylase 1.749e-12 0.62
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.897e-12 0.53
THB_HUMAN THRB Thyroid hormone receptor beta 2.17e-12 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.277e-12 0.71
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.517e-12 0.33
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 4.659e-12 0.41
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 9.593e-12 0.33
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.17e-11 0.28
TYTR_TRYCR TPR Trypanothione reductase 1.38e-11 0.61
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.99e-11 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.235e-11 0.57
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.821e-11 0.36
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 3.126e-11 0.30
TAU_HUMAN MAPT Microtubule-associated protein tau 8.329e-11 0.39
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 8.569e-11 0.40
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 9.301e-11 0.32
EST1_RABIT Liver carboxylesterase 1 2.244e-10 0.33
TSHR_HUMAN TSHR Thyrotropin receptor 3.175e-10 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 3.544e-10 0.46
CLK3_HUMAN CLK3 Dual specificity protein kinase CLK3 7.739e-10 0.45
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 8.38e-10 0.45
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 8.404e-10 0.37
DRD2_RAT Drd2 D(2) dopamine receptor 8.982e-10 0.49
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.24e-09 0.36
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.251e-09 0.65
MTSI_SPISQ sssIM CPG DNA methylase 1.37e-09 0.30
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 2.119e-09 0.34
ERM_STREE erm rRNA adenine N-6-methyltransferase 2.494e-09 0.29
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 3.598e-09 0.29
NK1R_HUMAN TACR1 Substance-P receptor 4.402e-09 0.40
KPYK_STAAR pyk Pyruvate kinase 4.526e-09 0.33
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.578e-09 0.39
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 5.398e-09 0.32
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 6.11e-09 0.65
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.237e-09 0.29
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.238e-08 0.47
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.395e-08 0.29
CHLE_HORSE BCHE Cholinesterase 1.724e-08 0.57
BAZ2A_HUMAN BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 2.819e-08 0.29
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 3.505e-08 0.29
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 3.887e-08 0.40
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 3.961e-08 0.36
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.985e-08 0.29
ACES_ELEEL ache Acetylcholinesterase 5.572e-08 0.57
Q7ZJM1_9HIV1 pol Integrase 5.656e-08 0.33
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 6.405e-08 0.36
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 7.169e-08 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.544e-08 0.34
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 7.964e-08 0.29
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 8.616e-08 0.36
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.022e-07 0.32
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 1.098e-07 0.36
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.101e-07 0.30
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.162e-07 0.28
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.272e-07 0.45
GPR84_HUMAN GPR84 G-protein coupled receptor 84 1.363e-07 0.60
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1.488e-07 0.29
STE24_YEAST STE24 CAAX prenyl protease 1 1.805e-07 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.895e-07 0.51
ECE1_RAT Ece1 Endothelin-converting enzyme 1 4.034e-07 0.30
Q9WTR4_RAT Slc6a2 Transporter 5.135e-07 0.52
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 6.172e-07 0.34
HDAC6_HUMAN HDAC6 Histone deacetylase 6 8.215e-07 0.36
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 9.518e-07 0.38
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.005e-06 0.46
NEP_RABIT MME Neprilysin 1.102e-06 0.34
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.102e-06 0.30
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.205e-06 0.33
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.223e-06 0.63
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.24e-06 0.29
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.709e-06 0.30
RYR2_HUMAN RYR2 Ryanodine receptor 2 1.939e-06 0.32
OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.036e-06 0.47
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 2.609e-06 0.45
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.754e-06 0.52
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.57e-06 0.52
GRIA1_RAT Gria1 Glutamate receptor 1 3.894e-06 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.411e-06 0.29
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 6.368e-06 0.36
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 7.02e-06 0.41
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.631e-06 0.34
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 8.023e-06 0.34
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 8.152e-06 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.209e-06 0.37
DRD3_HUMAN DRD3 D(3) dopamine receptor 8.94e-06 0.52
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 9.662e-06 0.31

Ganciclovir

HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 7.957e-188 0.58
PNPH_HUMAN PNP Purine nucleoside phosphorylase 2.257e-103 0.56
Q9HX69_PSEAE rocR RocR 6.398e-75 0.38
RASK_HUMAN KRAS GTPase KRas 2.244e-63 0.34
UL97_HCMVA UL97 Serine/threonine protein kinase UL97 3.645e-57 0.46
XGPT_ECOLI gpt Xanthine phosphoribosyltransferase 8.585e-57 0.45
Q6L709_HHV2 TK Thymidine kinase 8.238e-53 0.41
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 5.105e-49 0.34
PNPH_MOUSE Pnp Purine nucleoside phosphorylase 1.006e-46 0.47
HGPRT_MYCTU hpt Hypoxanthine-guanine phosphoribosyltransferase 2.649e-45 0.36
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 3.161e-44 0.54
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 3.161e-44 0.54
O54050_RHOCA xdhA Xanthine dehydrogenase 9.952e-40 0.31
X5EH84_STAAU folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 7.474e-39 0.36
KITH_HHV1 TK Thymidine kinase 1.425e-38 0.61
KITH_HHV1S TK Thymidine kinase 4.839e-38 0.41
PNPH_RAT Pnp Purine nucleoside phosphorylase 1.051e-32 0.52
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 1.863e-32 0.54
PNPH_BOVIN PNP Purine nucleoside phosphorylase 2.297e-30 0.48
Q3ZDS5_9HEPC NS5B 4.721e-28 0.35
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 1.322e-27 0.35
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 6.343e-22 0.31
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 6.966e-18 0.46
SAHH_HUMAN AHCY Adenosylhomocysteinase 3.553e-15 0.33
KITH_HUMAN TK1 Thymidine kinase, cytosolic 2.542e-14 0.60
DPOLB_HUMAN POLB DNA polymerase beta 1.722e-13 0.48
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 6.526e-13 0.38
UPP1_MOUSE Upp1 Uridine phosphorylase 1 8.981e-13 0.35
SAHH_RAT Ahcy Adenosylhomocysteinase 1.457e-12 0.33
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 3.945e-12 0.38
DPO3A_BACSU dnaE DNA polymerase III subunit alpha 5.199e-12 0.34
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 5.25e-12 0.38
DHPS_ECOLI folP Dihydropteroate synthase 6.647e-12 0.32
A3RLP8_CHV1 UL23 Thymidine kinase 1.215e-11 0.31
E1BN64_BOVIN PDE3B Phosphodiesterase 7.529e-11 0.37
O39930_9HEPC NS5b RNA-directed RNA polymerase 2.054e-08 0.35
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.699e-06 0.48

Dihydrotachysterol

VDR_HUMAN VDR Vitamin D3 receptor 1.444e-181 0.54
VDR_RAT Vdr Vitamin D3 receptor 6.259e-157 0.44
VDR_BOVIN VDR Vitamin D3 receptor 4.192e-104 0.42
VDR_CHICK VDR Vitamin D3 receptor 1.844e-87 0.41
VDRA_DANRE vdra Vitamin D3 receptor A 3.256e-73 0.41
VDR_PIG VDR Vitamin D3 receptor 6.625e-51 0.41
VTDB_HUMAN GC Vitamin D-binding protein 6.625e-51 0.41
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.915e-34 0.45
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 1.335e-19 0.31
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 7.022e-12 0.38
NR1H4_MOUSE Nr1h4 Bile acid receptor 4.32e-08 0.39
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 8.356e-07 0.39

Carphenazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.212e-139 0.68
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 6.225e-68 0.42
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.496e-62 0.63
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.036e-59 0.32
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 2.439e-58 0.31
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 2.151e-57 0.30
PRIO_MOUSE Prnp Major prion protein 2.703e-52 0.42
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.258e-49 0.31
TYTR_TRYCR TPR Trypanothione reductase 3.124e-46 0.46
DRD5_RAT Drd5 D(1B) dopamine receptor 3.322e-46 0.30
DRD1_PIG DRD1 D(1A) dopamine receptor 5.003e-45 0.33
LYSC1_RAT Lyz1 Lysozyme C-1 1.081e-42 0.53
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.903e-42 0.63
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.525e-42 0.63
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.832e-41 0.68
HRH1_HUMAN HRH1 Histamine H1 receptor 2.668e-37 0.63
DRD4_HUMAN DRD4 D(4) dopamine receptor 8.869e-37 0.63
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.848e-35 0.42
CALM_BOVIN CALM Calmodulin 1.174e-33 0.53
BGLR_RAT Gusb Beta-glucuronidase 6.151e-33 0.53
EBPL_HUMAN EBPL Emopamil-binding protein-like 6.151e-33 0.53
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 8.378e-33 0.68
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.946e-32 0.35
DRD2_RAT Drd2 D(2) dopamine receptor 8.887e-32 0.53
DRD4_RAT Drd4 D(4) dopamine receptor 1.99e-25 0.33
DRD3_RAT Drd3 D(3) dopamine receptor 2.859e-25 0.33
CALM1_HUMAN CALM1 Calmodulin-1 3.184e-25 0.53
CHLE_HUMAN BCHE Cholinesterase 4.244e-23 0.42
HRH2_HUMAN HRH2 Histamine H2 receptor 6.928e-19 0.63
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.148e-18 0.63
NOX1_HUMAN NOX1 NADPH oxidase 1 4.807e-18 0.43
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 6.964e-18 0.63
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.07e-17 0.35
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.743e-17 0.63
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.007e-17 0.43
ERG2_YEAST ERG2 C-8 sterol isomerase 2.22e-16 0.53
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.882e-16 0.63
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.221e-15 0.63
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.221e-15 0.57
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.554e-15 0.31
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.998e-15 0.63
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.554e-14 0.63
HRH3_RAT Hrh3 Histamine H3 receptor 3.131e-14 0.37
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.852e-14 0.53
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.54e-14 0.68
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 6.35e-14 0.31
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 7.616e-14 0.38
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.295e-13 0.35
DRD1_RAT Drd1 D(1A) dopamine receptor 3.205e-13 0.42
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.7e-13 0.63
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 6.64e-13 0.63
DRD1_HUMAN DRD1 D(1A) dopamine receptor 9.038e-13 0.63
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 1.064e-12 0.31
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.1e-12 0.35
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.838e-12 0.35
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 7.591e-12 0.29
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.107e-11 0.31
CHLE_HORSE BCHE Cholinesterase 2.682e-11 0.49
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 2.99e-11 0.32
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.261e-11 0.63
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 6.352e-11 0.35
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 7.792e-10 0.30
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.03e-09 0.31
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.803e-09 0.63
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 3.923e-09 0.63
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 7.297e-09 0.29
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.054e-08 0.40
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.09e-08 0.29
HRH1_RAT Hrh1 Histamine H1 receptor 1.501e-08 0.40
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.537e-08 0.63
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.825e-08 0.29
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 2.939e-08 0.30
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.063e-08 0.63
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 3.283e-08 0.29
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 4.845e-08 0.63
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 6.986e-08 0.43
PRIO_HUMAN PRNP Major prion protein 7.427e-08 0.53
DEF_STAAM def Peptide deformylase 8.746e-08 0.32
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 9.502e-08 0.42
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 9.548e-08 0.31
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.118e-07 0.63
WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.824e-07 0.53
DRD2_BOVIN DRD2 D(2) dopamine receptor 2.348e-07 0.42
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 2.43e-07 0.29
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 2.456e-07 0.53
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 2.843e-07 0.28
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 8.98e-07 0.31
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.052e-06 0.63
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.626e-06 0.38
ACES_RAT Ache Acetylcholinesterase 1.758e-06 0.32
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.33e-06 0.30
ACES_HUMAN ACHE Acetylcholinesterase 2.886e-06 0.41
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.971e-06 0.42
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 4.223e-06 0.31
ACES_ELEEL ache Acetylcholinesterase 4.848e-06 0.32
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 5.561e-06 0.42
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 7.106e-06 0.30
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 7.516e-06 0.30

Telithromycin

A5A4K8_RABIT MLNR Motilin receptor 3.791e-138 0.43
Q9XYC7_PLAFA HDAC1 Histone deacetylase 3.028e-37 0.52
ABCBB_HUMAN ABCB11 Bile salt export pump 5.329e-15 0.37
HDAC8_HUMAN HDAC8 Histone deacetylase 8 3.244e-13 0.55
MTLR_HUMAN MLNR Motilin receptor 1.778e-11 0.43
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 4.687e-11 0.51
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.962e-06 0.55
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 2.83e-06 0.55

Balsalazide

GLUC_HUMAN GCG Glucagon 2.998e-136 0.36
GLR_HUMAN GCGR Glucagon receptor 9.462e-92 0.36
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 7.93e-74 0.33
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 1.147e-49 0.36
GLR_RAT Gcgr Glucagon receptor 2.573e-48 0.31
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 1.697e-47 0.38
E2R517_CANLF GCGR Glucagon receptor 3.104e-39 0.31
GIPR_RAT Gipr Gastric inhibitory polypeptide receptor 9.698e-37 0.31
COMT_PIG COMT Catechol O-methyltransferase 3.815e-34 0.41
GLR_MOUSE Gcgr Glucagon receptor 1.746e-32 0.31
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.578e-28 0.33
POLG_CXB3N Genome polyprotein 3.105e-26 0.31
EGLN2_HUMAN EGLN2 Egl nine homolog 2 3.195e-21 0.38
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 7.533e-21 0.45
CO9_HUMAN C9 Complement component C9 3.462e-20 0.32
POLI_HUMAN POLI DNA polymerase iota 3.462e-20 0.32
DYN2_HUMAN DNM2 Dynamin-2 2.552e-18 0.35
POL_RSVP gag-pol Gag-Pol polyprotein 3.488e-18 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 3.934e-18 0.30
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 1.11e-16 0.32
POLH_HUMAN POLH DNA polymerase eta 1.11e-16 0.32
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.11e-16 0.50
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 5.551e-16 0.35
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 9.992e-16 0.32
EGLN1_HUMAN EGLN1 Egl nine homolog 1 1.932e-14 0.35
EGFR_MOUSE Egfr Epidermal growth factor receptor 1.307e-13 0.30
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.372e-13 0.30
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 1.861e-13 0.41
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.805e-12 0.30
AROB_ECOLI aroB 3-dehydroquinate synthase 7.616e-12 0.29
Q2PCB5_DICLA ca Carbonic anhydrase 8.327e-12 0.32
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 1.754e-11 0.31
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.828e-11 0.35
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.335e-11 0.33
ITB3_HUMAN ITGB3 Integrin beta-3 3.128e-11 0.41
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 1.002e-10 0.34
P2RX1_RAT P2rx1 P2X purinoceptor 1 1.96e-10 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 6.022e-10 0.34
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.85e-10 0.50
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.045e-09 0.28
ITA2_HUMAN ITGA2 Integrin alpha-2 1.124e-09 0.38
LYAM1_HUMAN SELL L-selectin 2.905e-09 0.30
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 7.368e-09 0.34
POLG_DEN2P Genome polyprotein 1.092e-08 0.38
CASP2_HUMAN CASP2 Caspase-2 1.429e-08 0.35
NEP_RAT Mme Neprilysin 1.479e-08 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 1.958e-08 0.33
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.148e-08 0.31
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 8.947e-08 0.32
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.291e-07 0.30
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.362e-07 0.29
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 3.805e-07 0.33
Q38C41_TRYB2 Phosphotransferase 4.174e-07 0.29
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.243e-07 0.31
MIP_LEGPN mip Outer membrane protein MIP 1.122e-06 0.28
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.368e-06 0.49
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.876e-06 0.30
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.939e-06 0.31
HDAC1_RAT Hdac1 Histone deacetylase 1 3.346e-06 0.29
O49150_SOLTU Lipoxygenase 4.23e-06 0.30
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 4.959e-06 0.32
THB_HUMAN THRB Thyroid hormone receptor beta 4.988e-06 0.30
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.484e-06 0.36

Arbutamine

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.227e-130 0.61
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.202e-126 0.56
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.161e-113 0.61
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 4.752e-103 0.53
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 9.143e-68 0.48
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.58e-61 0.48
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 1.112e-59 0.35
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.14e-54 0.55
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 9.185e-54 0.43
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 9.185e-54 0.43
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 5.937e-51 0.48
H9TVJ1_CHISP TyR1 1.127e-50 0.33
TYTR_CRIFA TPR Trypanothione reductase 2.856e-49 0.39
GRIA1_RAT Gria1 Glutamate receptor 1 9.638e-47 0.31
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.599e-46 0.48
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 4.236e-33 0.39
GRIA1_HUMAN GRIA1 Glutamate receptor 1 7.704e-29 0.32
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 8.092e-26 0.32
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 5.257e-25 0.39
NANA_STREE nanA Sialidase A 6.246e-22 0.34
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.933e-21 0.55
Q39829_SOYBN Lipoxygenase 1.446e-19 0.31
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.687e-19 0.50
G3HDX1_CRIGR Alpha-1B adrenergic receptor 1.882e-17 0.33
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.11e-16 0.32
PA_I000X PA Polymerase acidic protein 1.887e-15 0.29
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.998e-15 0.32
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 4.441e-15 0.36
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.144e-14 0.48
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.354e-14 0.29
POLG_CXB3N Genome polyprotein 4.219e-14 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 5.118e-14 0.32
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.661e-14 0.34
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.261e-12 0.32
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.182e-12 0.40
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.546e-11 0.49
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 3.173e-10 0.30
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 4.337e-10 0.54
TAT_HV1H2 tat Protein Tat 8.972e-10 0.28
AK1A1_HUMAN AKR1A1 Aldo-keto reductase family 1 member A1 1.498e-09 0.32
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 2.902e-09 0.49
COMT_PIG COMT Catechol O-methyltransferase 3.598e-09 0.29
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.643e-08 0.48
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.047e-08 0.48
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.925e-07 0.35
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.788e-07 0.30
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 2.8e-07 0.49
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.905e-07 0.29
ESR2_RAT Esr2 Estrogen receptor beta 5.231e-07 0.29
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 7.476e-07 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.099e-06 0.45
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.848e-06 0.50
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.361e-06 0.30
LEF_BACAN lef Lethal factor 3.918e-06 0.33
DPOLB_RAT Polb DNA polymerase beta 4.596e-06 0.29
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 5.525e-06 0.30
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 5.525e-06 0.30

Tocainide

PAG_BACAN pagA Protective antigen 1.874e-126 0.42
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 2.801e-54 0.44
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.733e-47 0.54
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 7.545e-40 0.32
SYL_STAA8 leuS Leucine--tRNA ligase 2.85e-39 0.31
AMPB_MOUSE Rnpep Aminopeptidase B 3.875e-36 0.29
AMPL_BOVIN LAP3 Cytosol aminopeptidase 3.875e-36 0.29
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 5.781e-35 0.37
LEF_BACAN lef Lethal factor 1.733e-29 0.42
SYL_ECOLI leuS Leucine--tRNA ligase 2.901e-25 0.31
AMPN_MOUSE Anpep Aminopeptidase N 9.044e-21 0.29
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.098e-20 0.40
AMPN_PIG ANPEP Aminopeptidase N 4.669e-19 0.50
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 4.879e-18 0.29
CATH_RAT Ctsh Pro-cathepsin H 6.785e-18 0.28
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.553e-17 0.32
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 4.345e-17 0.36
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 4.583e-17 0.33
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.22e-16 0.39
SHH_MOUSE Shh Sonic hedgehog protein 4.441e-16 0.35
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.11e-15 0.30
IL8_HUMAN CXCL8 Interleukin-8 1.443e-15 0.48
AGP1_YEAST AGP1 General amino acid permease AGP1 2.331e-15 0.53
NEP_MOUSE Mme Neprilysin 7.55e-15 0.33
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.166e-14 0.29
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 6.439e-14 0.45
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.492e-13 0.30
AMPB_RAT Rnpep Aminopeptidase B 1.898e-13 0.29
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.63e-12 0.33
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 2.315e-12 0.33
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 4.534e-12 0.34
AMPN_HUMAN ANPEP Aminopeptidase N 9.079e-12 0.50
AMPX_VIBPR Bacterial leucyl aminopeptidase 9.7e-12 0.29
NK1R_RAT Tacr1 Substance-P receptor 2.351e-11 0.33
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 4.705e-11 0.44
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 5.915e-11 0.33
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 4.884e-10 0.29
METC_ECOLI metC Cystathionine beta-lyase MetC 2.055e-09 0.38
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 2.663e-09 0.31
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 5.054e-09 0.33
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 6.837e-08 0.33
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 7.387e-08 0.29
ACRO_HUMAN ACR Acrosin 7.582e-08 0.35
AMPL_HUMAN LAP3 Cytosol aminopeptidase 9.851e-08 0.30
ROCK2_RAT Rock2 Rho-associated protein kinase 2 1.238e-07 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.631e-07 0.29
REV_HV1H2 rev Protein Rev 2.362e-07 0.29
CSK_HUMAN CSK Tyrosine-protein kinase CSK 2.41e-07 0.32
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.42e-07 0.39
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.905e-07 0.29
UREA_CANEN Urease 5.93e-07 0.31
BLA2_BACCE blm Metallo-beta-lactamase type 2 2.859e-06 0.31
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 3.908e-06 0.37
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.974e-06 0.33

Deslanoside

AT1A1_HUMAN ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 2.463e-122 0.79
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 8.134e-111 0.79
NOTC1_MOUSE Notch1 Neurogenic locus notch homolog protein 1 5.279e-104 0.58
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 2.902e-100 0.79
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 5.385e-89 0.79
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 8.129e-75 0.65
AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 3.253e-58 0.46
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 7.167e-52 0.79
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 7.167e-52 0.79
AT1A1_PIG ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1.009e-46 0.29
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 2.636e-37 0.46
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 1.366e-36 0.31
LEG4_HUMAN LGALS4 Galectin-4 5.046e-36 0.30
LEG8_HUMAN LGALS8 Galectin-8 5.046e-36 0.30
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 4.504e-35 0.79
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 9.36e-26 0.44
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 1.128e-12 0.35
TYRO_HUMAN TYR Tyrosinase 1.032e-11 0.29
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.69e-08 0.28
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.76e-07 0.88
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.1e-06 0.46
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 2.659e-06 0.79
IL2_HUMAN IL2 Interleukin-2 3.059e-06 0.33
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 4.532e-06 0.79

Sulfamethoxazole

PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 7.136e-112 0.53
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 4.931e-111 0.53
BRD4_MOUSE Brd4 Bromodomain-containing protein 4 2.148e-58 0.37
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 5.385e-56 0.37
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.015e-47 0.32
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 3.5e-45 0.30
LN28A_MOUSE Lin28a Protein lin-28 homolog A 8.416e-44 0.35
Q56D22_MACMU HSD11B1 Hydroxysteroid 11-beta dehydrogenase 1 1.353e-43 0.35
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 1.738e-37 0.30
CYNT_HELPY cynT Carbonic anhydrase 1.885e-32 0.41
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 6.242e-32 0.38
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.466e-31 0.45
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 1.631e-31 0.33
SC5A7_RAT Slc5a7 High affinity choline transporter 1 5.179e-28 0.35
Q81VW8_BACAN folP Dihydropteroate synthase 1.282e-27 0.48
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 2.735e-27 0.45
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 5.351e-27 0.59
C0IX24_STYPI CA2 Carbonic anhydrase 8.134e-27 0.41
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 1.079e-26 0.38
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 2.022e-26 0.39
B2V8E3_SULSY Carbonate dehydratase 8.55e-26 0.41
B5SU02_STYPI CA Alpha carbonic anhydrase 8.55e-26 0.41
Q31FD6_HYDCU Carbonic anhydrase, alpha family 8.55e-26 0.41
A6YCJ1_9METZ Astrosclerin-3 1.957e-24 0.41
EDNRA_HUMAN EDNRA Endothelin-1 receptor 7.598e-24 0.43
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.654e-23 0.36
EDNRA_RAT Ednra Endothelin-1 receptor 6.281e-22 0.59
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 9.759e-22 0.41
Q5XX84_CANLF HSD11B1 11-beta-hydroxysteroid dehydrogenase type 1 1.126e-21 0.35
ARY2_MOUSE Nat2 Arylamine N-acetyltransferase 2 2.233e-21 0.35
KMO_RAT Kmo Kynurenine 3-monooxygenase 3.518e-21 0.36
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.247e-20 0.37
FFAR4_RAT Ffar4 Free fatty acid receptor 4 1.145e-19 0.38
CAN_YEAST NCE103 Carbonic anhydrase 2.344e-19 0.41
ARY1_HUMAN NAT1 Arylamine N-acetyltransferase 1 4.171e-19 0.35
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 4.887e-19 0.39
CAH_METTE Carbonic anhydrase 7.902e-19 0.36
Q548M1_ECOLX groL 60 kDa chaperonin 1.132e-17 0.40
Q7BGE6_ECOLX groES 10 kDa chaperonin 1.132e-17 0.40
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.407e-17 0.45
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 4.805e-17 0.41
METC_ECOLI metC Cystathionine beta-lyase MetC 5.551e-16 0.36
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.885e-15 0.41
CAH15_MOUSE Ca15 Carbonic anhydrase 15 7.883e-15 0.36
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.216e-15 0.41
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.331e-14 0.45
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 4.94e-14 0.36
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 6.495e-14 0.36
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 8.66e-14 0.37
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.14e-13 0.44
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 1.339e-11 0.32
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 1.96e-11 0.38
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.62e-11 0.47
CAH2_HUMAN CA2 Carbonic anhydrase 2 8.523e-11 0.46
CAN_CANAL NCE103 Carbonic anhydrase 1.089e-10 0.41
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 1.26e-10 0.30
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 2.873e-10 0.35
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.87e-09 0.45
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.983e-09 0.41
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.406e-09 0.29
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.837e-09 0.55
BRD3_HUMAN BRD3 Bromodomain-containing protein 3 4.947e-09 0.38
EDNRB_HUMAN EDNRB Endothelin receptor type B 7.436e-09 0.41
HDAC4_HUMAN HDAC4 Histone deacetylase 4 1.116e-08 0.35
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.685e-08 0.41
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.951e-08 0.47
BRPF1_HUMAN BRPF1 Peregrin 3.218e-08 0.30
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 4.191e-08 0.37
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.714e-07 0.30
5NTD_HUMAN NT5E 5'-nucleotidase 2.741e-07 0.35
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 4.296e-07 0.30
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 6.571e-07 0.30
POLG_DEN2P Genome polyprotein 1.198e-06 0.28
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.252e-06 0.41
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.302e-06 0.35
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 1.557e-06 0.35
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.629e-06 0.30
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 2.936e-06 0.49
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 4.706e-06 0.35
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.132e-06 0.41
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 8.181e-06 0.35
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 8.239e-06 0.49
CAH3_HUMAN CA3 Carbonic anhydrase 3 8.804e-06 0.36

Glipizide

HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.034e-109 0.47
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 6.134e-76 0.47
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.786e-50 0.35
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 3.582e-45 0.30
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 1.857e-33 0.42
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.156e-29 0.47
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.403e-25 0.41
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 8.436e-25 0.47
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 4.406e-24 0.59
ABCBB_RAT Abcb11 Bile salt export pump 1.539e-23 0.59
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 1.17e-22 0.36
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 5.211e-21 0.34
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.989e-18 0.48
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.687e-17 0.59
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.22e-16 0.38
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.331e-16 0.48
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 5.551e-16 0.34
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.22e-15 0.59
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 5.329e-15 0.41
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.015e-13 0.37
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 4.482e-13 0.32
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 7.399e-13 0.32
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.964e-12 0.40
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 2.223e-12 0.37
ADA17_MOUSE Adam17 Disintegrin and metalloproteinase domain-containing protein 17 2.847e-12 0.30
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.525e-12 0.48
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 4.181e-12 0.30
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 8.04e-12 0.30
CNR2_HUMAN CNR2 Cannabinoid receptor 2 8.762e-12 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 9.469e-12 0.37
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.216e-11 0.30
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.389e-11 0.33
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.571e-11 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.996e-11 0.34
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 7.526e-11 0.29
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 8.353e-11 0.40
NMT1_HUMAN NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1.439e-10 0.32
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.85e-10 0.33
CPNS1_PIG CAPNS1 Calpain small subunit 1 3.026e-10 0.28
CAH12_HUMAN CA12 Carbonic anhydrase 12 4.303e-10 0.48
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 5.554e-10 0.35
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 8.499e-10 0.34
ERG_HUMAN ERG Transcriptional regulator ERG 1.072e-09 0.28
PANC_MYCTU panC Pantothenate synthetase 6.08e-09 0.36
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.404e-09 0.34
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.414e-08 0.40
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.494e-08 0.34
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.552e-08 0.34
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 4.612e-08 0.40
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.581e-07 0.42
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.599e-07 0.33
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.033e-07 0.34
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 2.649e-07 0.32
GRM1_RAT Grm1 Metabotropic glutamate receptor 1 5.722e-07 0.38
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 6.005e-07 0.38
QPCTL_HUMAN QPCTL Glutaminyl-peptide cyclotransferase-like protein 7.32e-07 0.32
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 8.676e-07 0.31
MMP3_HUMAN MMP3 Stromelysin-1 8.932e-07 0.34
PRIO_MESAU PRNP Major prion protein 2.028e-06 0.29

Thalidomide

IKZF1_HUMAN IKZF1 DNA-binding protein Ikaros 6.329e-101 0.74
CRBN_HUMAN CRBN Protein cereblon 9.321e-84 0.74
A4TVL0_9PROT Cereblon isoform 4 1.239e-23 0.29
CCG8_HUMAN CACNG8 Voltage-dependent calcium channel gamma-8 subunit 2.22e-15 0.29
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 1.099e-14 0.33
AGRA_STAAU agrA Accessory gene regulator protein A 5.427e-12 0.29

Cefditoren

PBPA_PSEAE mrcA Penicillin-binding protein 1A 7.137e-86 0.40
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 7.44e-74 0.65
B2ZTR6_ACIBA Beta-lactamase 1.481e-64 0.65
D6NSM8_ACIBA ampC Beta-lactamase 1.481e-64 0.65
Q83TT7_ECOLX ampC AmpC 3.15e-58 0.40
Q7DHH4_STAAU mecA MecA 5.341e-50 0.40
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.447e-45 0.65
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.268e-41 0.65
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.376e-32 0.40
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.335e-27 0.34
Q3S5C3_SALNE sugE Efflux transporter 3.477e-25 0.40
Q48435_KLEPN bla LAT-2 Beta-lactamase 3.477e-25 0.40
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.44e-18 0.34
A2RP81_CITFR blaPER-2 Beta-lactamase 2.987e-18 0.40
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.866e-17 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.109e-15 0.63
AMPC_CITFR ampC Beta-lactamase 2.573e-13 0.33
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 3.404e-13 0.62
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.069e-06 0.63
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 9.675e-06 0.62

Lomefloxacin

ACEA_MYCTU icl Isocitrate lyase 1.75e-83 0.56
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.633e-65 0.52
Q47245_ECOLX gyrA DNA gyrase subunit A 1.652e-65 0.46
C3SLN2_ECOLX gyrB DNA gyrase subunit B 1.016e-56 0.46
GLYCP_NIPAV G Glycoprotein G 2.371e-32 0.32
DPO3_BACSU polC DNA polymerase III PolC-type 3.122e-26 0.46
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 3.362e-22 0.40
PARC_STAAU parC DNA topoisomerase 4 subunit A 4.747e-21 0.62
DPO1_THEAQ polA DNA polymerase I, thermostable 3.126e-19 0.39
GYRA_MYCTU gyrA DNA gyrase subunit A 1.11e-16 0.62
GYRA_STAAU gyrA DNA gyrase subunit A 3.553e-15 0.47
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 8.386e-12 0.43
GYRA_ECOLI gyrA DNA gyrase subunit A 4.195e-11 0.47
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.337e-10 0.33
GYRB_STAAU gyrB DNA gyrase subunit B 1.147e-08 0.47
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.838e-08 0.43
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.848e-07 0.33
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 1.556e-06 0.30
Q76353_9HIV1 Integrase 2.343e-06 0.33
STRP_STRP1 ska Streptokinase A 3.499e-06 0.62
PARE_STAAU parE DNA topoisomerase 4 subunit B 4.525e-06 0.40

Nandrolone_phenpropionate

S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.756e-79 0.40
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.864e-59 0.40
TAT_HV112 tat Protein Tat 3.326e-44 0.35
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 9.538e-41 0.35
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 2.983e-40 0.34
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.962e-32 0.43
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 8.173e-30 0.36
Q690N0_BOVIN PGR Progesterone receptor 2.541e-29 0.43
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.161e-25 0.35
F1Q298_CANLF NR3C1 Glucocorticoid receptor 9.841e-25 0.30
GCR_PIG NR3C1 Glucocorticoid receptor 9.841e-25 0.30
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.776e-24 0.35
PRGR_RABIT PGR Progesterone receptor 8.344e-22 0.48
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 3.889e-21 0.34
PRGR_RAT Pgr Progesterone receptor 1.479e-19 0.43
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 6.109e-18 0.28
CP19A_HUMAN CYP19A1 Aromatase 8.636e-18 0.46
ANDR_RAT Ar Androgen receptor 6.661e-16 0.49
STS_HUMAN STS Steryl-sulfatase 1.821e-14 0.35
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 6.806e-14 0.30
ANDR_HUMAN AR Androgen receptor 9.348e-14 0.49
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.69e-13 0.34
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 3.469e-13 0.28
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.334e-12 0.31
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.457e-11 0.29
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 5.268e-11 0.35
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.774e-11 0.34
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.068e-10 0.31
PRGR_HUMAN PGR Progesterone receptor 2.376e-10 0.47
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 6.756e-10 0.31
ANDR_MOUSE Ar Androgen receptor 1.019e-09 0.49
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.724e-09 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.649e-09 0.49
ERG2_YEAST ERG2 C-8 sterol isomerase 6.848e-09 0.34
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 7.856e-09 0.29
Q4QYD9_RAT Heat sensitive channel TRPV3 9.651e-09 0.29
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.633e-08 0.34
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.324e-08 0.34
BLA1_ECOLX bla Beta-lactamase SHV-1 8.386e-08 0.33
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 9.038e-08 0.35
MGLL_RAT Mgll Monoglyceride lipase 3.902e-07 0.30
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.63e-07 0.40
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 9.501e-07 0.31
AMPC_ECOLI ampC Beta-lactamase 2.72e-06 0.35

Cyclopentolate

AMYP_RAT Amy2 Pancreatic alpha-amylase 1.021e-73 0.40
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.278e-64 0.35
UR2R_HUMAN UTS2R Urotensin-2 receptor 4.081e-29 0.33
BLAB_BACCE Metallo-beta-lactamase type 2 7.085e-27 0.30
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 4.551e-26 0.35
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 9.504e-18 0.34
Q8WMX0_BOVIN Muscarinic receptor M1 1.11e-16 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.22e-16 0.50
OPRX_HUMAN OPRL1 Nociceptin receptor 9.992e-16 0.37
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 5.196e-14 0.29
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 8.671e-14 0.42
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.775e-12 0.33
Q63380_RAT NET Transporter 1.834e-12 0.40
AOC3_HUMAN AOC3 Membrane primary amine oxidase 3.622e-12 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.734e-12 0.76
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 6.471e-12 0.33
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 6.733e-12 0.29
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 8.441e-12 0.76
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.827e-11 0.76
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 3.972e-11 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.352e-10 0.40
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.932e-10 0.50
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.21e-10 0.44
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.717e-10 0.36
Q9WTR4_RAT Slc6a2 Transporter 8.745e-10 0.50
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.072e-09 0.76
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.167e-09 0.33
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 9.001e-09 0.42
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4.214e-08 0.29
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 4.633e-08 0.30
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 5.134e-08 0.33
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 6.887e-08 0.37
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.062e-07 0.36
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.402e-07 0.34
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 2.543e-07 0.30
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 2.645e-07 0.28
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.843e-07 0.36
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.696e-07 0.44
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 5.194e-07 0.44
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 6.44e-07 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 9.333e-07 0.30
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.266e-06 0.30
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.489e-06 0.29
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.809e-06 0.37
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.463e-06 0.43
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.476e-06 0.42
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 2.558e-06 0.29
PI2R_HUMAN PTGIR Prostacyclin receptor 2.736e-06 0.34
BLA2_BACCE blm Metallo-beta-lactamase type 2 3.572e-06 0.30
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 3.609e-06 0.35
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 4.596e-06 0.29

Phylloquinone

GSHR_PLAF7 GR3 Glutathione reductase 5.258e-64 0.42
TYTR_TRYCR TPR Trypanothione reductase 4.376e-40 0.39
VKOR1_BOVIN VKORC1 Vitamin K epoxide reductase complex subunit 1 1.431e-33 0.54
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 8.847e-28 0.53
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 4.676e-18 0.42
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 9.897e-07 0.33
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.477e-06 0.28
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 3.637e-06 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 6.279e-06 0.29

Deserpidine

S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.228e-63 0.30
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 5.692e-51 0.64
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.036e-43 0.84
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 8.977e-33 0.84
GPVI_HUMAN GP6 Platelet glycoprotein VI 2.847e-23 0.29
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.388e-21 0.84
TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 2.116e-20 0.36
Q25270_LEIDO beta-tubulin Beta-tubulin 3.757e-18 0.30
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.581e-17 0.64
TLR4_HUMAN TLR4 Toll-like receptor 4 4.387e-17 0.32
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 4.33e-15 0.31
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.144e-14 0.84
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 3.854e-13 0.64
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.148e-13 0.64
DRD1_HUMAN DRD1 D(1A) dopamine receptor 6.292e-13 0.34
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.117e-12 0.34
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.686e-12 0.64
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 5.561e-12 0.64
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 4.487e-11 0.30
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 7.648e-11 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.268e-09 0.33
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.629e-09 0.31
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 9.822e-09 0.84
NORA_STAAU norA Quinolone resistance protein NorA 1.262e-08 0.84
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.88e-08 0.30
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.368e-08 0.31
Q49PX0_9POXV N1L N1L 4.468e-08 0.28
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 5.897e-08 0.31
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 6.537e-08 0.64
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 1.003e-07 0.32
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.163e-07 0.31
TF_HUMAN F3 Tissue factor 1.257e-07 0.33
AA2BR_RAT Adora2b Adenosine receptor A2b 2.725e-07 0.64
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 5.262e-07 0.49
PLD1_RAT Pld1 Phospholipase D1 8.498e-07 0.34
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 8.874e-07 0.64
MIP_LEGPN mip Outer membrane protein MIP 1.08e-06 0.28
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.239e-06 0.32
KLK7_HUMAN KLK7 Kallikrein-7 2.783e-06 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.927e-06 0.35
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 4.267e-06 0.64
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.455e-06 0.30
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 5.988e-06 0.30
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 9.349e-06 0.29

Trilostane

TAT_HV112 tat Protein Tat 1.552e-59 0.52
Q95MF8_PIG Sulfotransferase 8.646e-56 0.32
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.354e-44 0.38
SHBG_RAT Shbg Sex hormone-binding globulin 1.275e-29 0.37
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.153e-26 0.38
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.956e-21 0.31
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 6.654e-21 0.33
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.369e-20 0.33
ANDR_RAT Ar Androgen receptor 1.11e-16 0.40
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.221e-15 0.35
CP19A_HUMAN CYP19A1 Aromatase 1.271e-13 0.42
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 2.315e-13 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 3.909e-13 0.37
Q690N0_BOVIN PGR Progesterone receptor 2.078e-12 0.37
ANDR_HUMAN AR Androgen receptor 1.877e-11 0.37
ESR1_MOUSE Esr1 Estrogen receptor 2.049e-10 0.33
ESR2_MOUSE Esr2 Estrogen receptor beta 2.049e-10 0.33
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 6.146e-10 0.30
ESR1_HUMAN ESR1 Estrogen receptor 3.086e-09 0.37
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.3e-07 0.33
ANDR_MOUSE Ar Androgen receptor 3.407e-06 0.37
MCR_RAT Nr3c2 Mineralocorticoid receptor 4.431e-06 0.37

Capecitabine

ADK_HUMAN ADK Adenosine kinase 1.547e-58 0.47
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 9.496e-54 0.43
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 1.622e-52 0.35
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 4.756e-47 0.35
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 2.325e-39 0.34
POLG_POL1M Genome polyprotein 1.674e-38 0.30
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 8.648e-35 0.33
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 7.235e-32 0.31
ASAH1_RAT Asah1 Acid ceramidase 7.951e-30 0.30
KITH_VZVO TK Thymidine kinase 1.208e-27 0.34
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 1.282e-24 0.29
FTSZ_MYCTU ftsZ Cell division protein FtsZ 1.529e-23 0.29
ADA_MOUSE Ada Adenosine deaminase 4.185e-23 0.28
MRAY_BACSU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 2.576e-18 0.29
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 3.72e-18 0.29
AA3R_RAT Adora3 Adenosine receptor A3 2.22e-16 0.32
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.998e-15 0.33
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 5.218e-14 0.29
ENV_HV1H2 env Envelope glycoprotein gp160 3.922e-13 0.29
P2RY1_RAT P2ry1 P2Y purinoceptor 1 5.476e-13 0.28
AA1R_RAT Adora1 Adenosine receptor A1 1.629e-12 0.36
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 3.346e-11 0.31
AA2AR_RAT Adora2a Adenosine receptor A2a 3.93e-10 0.36
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 5.866e-10 0.29
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 2.343e-09 0.29
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.851e-09 0.29
RASK_HUMAN KRAS GTPase KRas 3.431e-09 0.28
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 4.536e-09 0.31
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 3.37e-08 0.29
ASAH1_HUMAN ASAH1 Acid ceramidase 5.356e-07 0.30
CDD_MOUSE Cda Cytidine deaminase 5.464e-07 0.28
CDD_HUMAN CDA Cytidine deaminase 3.133e-06 0.28
ADK_RAT Adk Adenosine kinase 4.506e-06 0.33
P2RX1_RAT P2rx1 P2X purinoceptor 1 5.131e-06 0.31
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 6.008e-06 0.30
C3SIU2_ECOLX metJ Met repressor 7.607e-06 0.28

Vigabatrin

FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 4.369e-55 0.38
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 5.166e-42 0.33
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.166e-42 0.33
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 1.921e-39 0.31
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.814e-38 0.35
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 3.875e-36 0.29
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 4.231e-31 0.40
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 5.899e-31 0.46
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 7.011e-29 0.35
GGH_HUMAN GGH Gamma-glutamyl hydrolase 9.393e-28 0.34
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 6.243e-24 0.29
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 3.462e-20 0.32
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 7.563e-20 0.32
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 3.122e-19 0.31
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 9.056e-18 0.28
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.882e-17 0.33
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 3.331e-16 0.37
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.221e-15 0.30
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 5.018e-14 0.32
Q9I056_PSEAE cpg2 Carboxypeptidase G2 7.55e-14 0.30
GLN1B_ECOLI glnA Glutamine synthetase 1.704e-13 0.29
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 5.528e-12 0.31
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 2.335e-11 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.335e-11 0.33
Q6RY99_RAT Tetraspanin 4.757e-11 0.30
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 1.517e-10 0.31
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 4.123e-10 0.31
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 1.709e-08 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.403e-08 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.323e-07 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 2.554e-07 0.32
DCOR_RAT Odc1 Ornithine decarboxylase 2.994e-07 0.28
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 3.888e-07 0.32
Q6UB75_PIG Group VII phospholipase A2 4.905e-07 0.29
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 5.944e-07 0.33
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 6.637e-07 0.32
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 8.358e-07 0.30
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 8.358e-07 0.30
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 9.875e-07 0.33
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 1.166e-06 0.34
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.643e-06 0.34
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.923e-06 0.32
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 5.201e-06 0.33
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 5.237e-06 0.31
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 6.801e-06 0.30

Streptomycin

AMYP_HUMAN AMY2A Pancreatic alpha-amylase 5.433e-55 0.33
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 2.417e-52 0.36
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 5.879e-29 0.28
CHIT_YEAST CTS1 Endochitinase 1.208e-27 0.34
MAG_HUMAN MAG Myelin-associated glycoprotein 4.796e-23 0.32
LEG4_HUMAN LGALS4 Galectin-4 3.983e-19 0.30
LEG8_HUMAN LGALS8 Galectin-8 3.983e-19 0.30
FGF1_HUMAN FGF1 Fibroblast growth factor 1 2.22e-16 0.29
CD69_HUMAN CD69 Early activation antigen CD69 6.661e-16 0.39
AMY1A_HUMAN AMY1A Alpha-amylase 1 8.882e-16 0.30
P94451_GEOSE Alpha-amylase 9.504e-14 0.30
LEG3_HUMAN LGALS3 Galectin-3 1.99e-13 0.31
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.029e-13 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 9.639e-10 0.29
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 7.799e-08 0.29
LEF_BACAN lef Lethal factor 4.362e-07 0.40
CHIA_HUMAN CHIA Acidic mammalian chitinase 1.763e-06 0.34
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 3.897e-06 0.28
CHIB_SERMA chiB Chitinase B 5.491e-06 0.34

Minocycline

MDFA_ECOLI mdfA Multidrug transporter MdfA 2.106e-45 0.47

Ethinamate

G3P_RABIT GAPDH Glyceraldehyde-3-phosphate dehydrogenase 3.43e-44 0.31

Amoxicillin

S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.313e-42 0.53
BLAB_BACCE Metallo-beta-lactamase type 2 9.34e-38 0.43
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 3.04e-35 0.44
Q3S5C3_SALNE sugE Efflux transporter 3.19e-27 0.44
Q48435_KLEPN bla LAT-2 Beta-lactamase 3.19e-27 0.44
A2RP81_CITFR blaPER-2 Beta-lactamase 5.55e-23 0.51
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 5.295e-17 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.331e-15 0.53
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.225e-12 0.53
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 3.72e-12 0.31
AMPC_ECOLI ampC Beta-lactamase 6.333e-12 0.49
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.508e-10 0.28
Q82134_9DELA prt Protease 2.07e-10 0.29
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.19e-09 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.702e-09 0.32
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.008e-09 0.31
OPRD_RAT Oprd1 Delta-type opioid receptor 1.454e-07 0.32
OPRM_CAVPO OPRM1 Mu-type opioid receptor 4.471e-07 0.31
OPRX_CAVPO OPRL1 Nociceptin receptor 3.531e-06 0.28
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.608e-06 0.30

Azathioprine

5HT3C_HUMAN HTR3C 5-hydroxytryptamine receptor 3C 5.166e-42 0.33
5HT3E_HUMAN HTR3E 5-hydroxytryptamine receptor 3E 5.166e-42 0.33
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.882e-17 0.33
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 5.388e-09 0.46
SOAT1_MOUSE Soat1 Sterol O-acyltransferase 1 8.882e-08 0.33
RT109_YEAST RTT109 Histone acetyltransferase RTT109 9.052e-07 0.46

Cyclacillin

BLAB_BACCE Metallo-beta-lactamase type 2 1.346e-40 0.46
D5HSX5_9GAMM blaPER-6 Beta-lactamase 5.06e-39 0.31
Q0VTR6_ACIPI adc-14 Beta-lactamase 5.06e-39 0.31
Q0VTR8_ACIPI adc-16 Beta-lactamase 5.06e-39 0.31
Q7X575_ECOLX SHV-11 Beta-lactamase 5.06e-39 0.31
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 5.293e-34 0.42
Q3S5C3_SALNE sugE Efflux transporter 2.856e-26 0.42
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.856e-26 0.42
A1E3K9_ECOLX blaSCO-1 Beta-lactamase 4.179e-25 0.31
A8RR46_BACCS bcl1 Beta-lactamase 4.179e-25 0.31
D2SSQ3_PSEAI Beta-lactamase 4.179e-25 0.31
Q3SAW3_PSEAI bla(BEL1) Beta-lactamase 4.179e-25 0.31
AMPC_CITFR ampC Beta-lactamase 5.514e-23 0.29
BLAC_BACLI penP Beta-lactamase 5.514e-23 0.29
A2RP81_CITFR blaPER-2 Beta-lactamase 1.609e-20 0.46
D1MIX9_PSEAI blaGES-13 Beta-lactamase 1.913e-19 0.31
AMPC_ENTCL ampC Beta-lactamase 1.066e-14 0.32
AMPC_ECOLI ampC Beta-lactamase 3.976e-12 0.50

Hydroxyurea

Q0PXQ5_HELPX ureB Urease subunit beta 3.824e-40 0.32
AMPX_VIBPR Bacterial leucyl aminopeptidase 4.008e-23 0.29
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 4.707e-07 0.30

Clonazepam

NCLX_HUMAN SLC8B1 Mitochondrial sodium/calcium exchanger protein 1.071e-38 0.31
NCAP_I33A0 NP Nucleoprotein 1.42e-25 0.32
S27A2_HUMAN SLC27A2 Very long-chain acyl-CoA synthetase 1.685e-24 0.30
SYUA_HUMAN SNCA Alpha-synuclein 2.457e-21 0.40
PGH1_RABIT PTGS1 Prostaglandin G/H synthase 1 2.788e-21 0.35
PGH2_RABIT PTGS2 Prostaglandin G/H synthase 2 6.551e-20 0.35
CCG8_HUMAN CACNG8 Voltage-dependent calcium channel gamma-8 subunit 3.331e-15 0.29
HPPD_RAT Hpd 4-hydroxyphenylpyruvate dioxygenase 1.01e-14 0.32
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.642e-14 0.41
TAU_HUMAN MAPT Microtubule-associated protein tau 1.849e-13 0.37
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 1.364e-12 0.43
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.545e-12 0.37
I23O2_HUMAN IDO2 Indoleamine 2,3-dioxygenase 2 8.819e-12 0.32
CASP4_HUMAN CASP4 Caspase-4 6.665e-11 0.36
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 1.369e-10 0.28
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 1.667e-10 0.48
TAT_HV112 tat Protein Tat 2.873e-10 0.47
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 4.569e-10 0.29
CASP9_HUMAN CASP9 Caspase-9 6.539e-10 0.36
H9B8T9_CAPHI CTSB Cathepsin B 1.379e-09 0.30
A0A060INS8_CAPHI CTSH Cathepsin H 3.825e-09 0.30
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 1.563e-08 0.43
OXDA_PIG DAO D-amino-acid oxidase 2.026e-08 0.30
KPCG_RAT Prkcg Protein kinase C gamma type 5.758e-08 0.32
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.199e-07 0.28
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.393e-07 0.41
CAH11_HUMAN CA11 Carbonic anhydrase-related protein 11 2.22e-07 0.30
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 2.38e-07 0.30
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 1.244e-06 0.28
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 2.859e-06 0.31
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 7.718e-06 0.38
Q8MWR1_SPOFR USP Ultraspiracle protein 8.152e-06 0.29
Q8MWR2_SPOFR EcR Ecdysteroid receptor 8.152e-06 0.29

Fenofibrate

FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.028e-36 0.67
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 4.527e-34 0.67
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 4.45e-30 0.43
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 3.799e-29 0.43
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.448e-28 0.43
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 5.475e-25 0.43
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 7.953e-20 0.38
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 2.147e-19 0.43
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 3.008e-18 0.38
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.878e-17 0.39
EST1_RABIT Liver carboxylesterase 1 5.407e-14 0.35
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.826e-12 0.45
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.971e-11 0.51
XPO1_HUMAN XPO1 Exportin-1 1.253e-09 0.36
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 1.483e-09 0.35
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 1.307e-08 0.43
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.589e-08 0.30
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 4.751e-08 0.43
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.84e-07 0.31
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.955e-07 0.34
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.24e-07 0.42
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 3.556e-07 0.38
EST2_HUMAN CES2 Cocaine esterase 4.23e-07 0.35
LSS_RAT Lss Lanosterol synthase 4.587e-07 0.38
THB_RAT Thrb Thyroid hormone receptor beta 5.354e-07 0.30
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.349e-06 0.34
ELNE_HUMAN ELANE Neutrophil elastase 2.138e-06 0.56
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 2.475e-06 0.32
ECR_BOMMO EcR Ecdysone receptor 6.129e-06 0.31
Q8MWR1_SPOFR USP Ultraspiracle protein 6.947e-06 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 6.947e-06 0.30
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 7.112e-06 0.29
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 7.724e-06 0.34
USP_DROME usp Protein ultraspiracle 9.449e-06 0.31

Lubiprostone

SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 1.088e-32 0.41
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.228e-27 0.41
PPM1A_HUMAN PPM1A Protein phosphatase 1A 4.212e-24 0.30
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.159e-20 0.41
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.393e-17 0.41
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 6.328e-15 0.41
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 7.55e-15 0.41
TRAR_RHIRD traR Transcriptional activator protein TraR 4.201e-11 0.29
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.923e-10 0.30
LUXR_ALIFS luxR Transcriptional activator protein LuxR 4.629e-10 0.29
PI2R_HUMAN PTGIR Prostacyclin receptor 5.886e-10 0.41
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 5.075e-09 0.36
LASR_PSEAE lasR Transcriptional activator protein LasR 2.226e-08 0.29
O07911_STAAU agrC AgrC 3.985e-08 0.29
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.105e-07 0.29
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 1.146e-06 0.37
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.842e-06 0.41
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.859e-06 0.31
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 7.112e-06 0.29

Auranofin

CAH12_HUMAN CA12 Carbonic anhydrase 12 1.076e-27 0.50
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.536e-26 0.50
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.893e-23 0.41
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.16e-20 0.50
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 3.333e-19 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.317e-18 0.50
AMY1A_HUMAN AMY1A Alpha-amylase 1 4.441e-16 0.31
Q194T1_9INFA Neuraminidase 5.884e-15 0.28
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 7.263e-07 0.41
CAH13_HUMAN CA13 Carbonic anhydrase 13 8.06e-07 0.41
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.202e-06 0.41
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 7.67e-06 0.41

Isosorbide_mononitrate

GSHR_HUMAN GSR Glutathione reductase, mitochondrial 2.633e-27 0.50

Guanfacine

S100B_HUMAN S100B Protein S100-B 3.382e-26 0.46
1433S_HUMAN SFN 14-3-3 protein sigma 5.379e-25 0.31
IL8_HUMAN CXCL8 Interleukin-8 3.041e-19 0.36
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 2.22e-16 0.33
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 4.441e-15 0.35
CBPB1_PIG CPB1 Carboxypeptidase B 1.246e-13 0.30
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 4.66e-13 0.30
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 1.729e-12 0.41
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 7.616e-12 0.29
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 1.275e-11 0.28
H9B8T9_CAPHI CTSB Cathepsin B 1.939e-11 0.39
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.884e-11 0.36
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 1.559e-10 0.31
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 3.051e-10 0.36
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.906e-10 0.32
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 1.591e-09 0.36
TTHY_HUMAN TTR Transthyretin 1.814e-09 0.36
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.4e-09 0.29
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 4.055e-09 0.35
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 8.206e-09 0.29
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.275e-08 0.46
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 6.665e-08 0.31
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 2.137e-07 0.36
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.955e-07 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 9.514e-07 0.36
NISCH_HUMAN NISCH Nischarin 1.304e-06 0.57
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.365e-06 0.31
CAN_CANAL NCE103 Carbonic anhydrase 2.103e-06 0.32
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 3.403e-06 0.32
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 3.403e-06 0.32
FEN1_HUMAN FEN1 Flap endonuclease 1 4.046e-06 0.36
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.96e-06 0.40
BLA2_BACCE blm Metallo-beta-lactamase type 2 5.327e-06 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 8.27e-06 0.36

Mercaptopurine

GUAD_HUMAN GDA Guanine deaminase 1.141e-24 0.39
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 3.763e-19 0.33
AA1R_CAVPO ADORA1 Adenosine receptor A1 2.22e-16 0.39

Echothiophate

DXS_ECO27 dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.248e-24 0.30
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 4.43e-19 0.30

Dimenhydrinate

SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.693e-20 0.37
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 3.22e-15 0.35
AA1R_RAT Adora1 Adenosine receptor A1 4.208e-14 0.41
AA1R_BOVIN ADORA1 Adenosine receptor A1 8.157e-13 0.41
AA2AR_RAT Adora2a Adenosine receptor A2a 1.578e-11 0.36
A3RLP8_CHV1 UL23 Thymidine kinase 2.083e-11 0.31
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 2.35e-11 0.41
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.569e-08 0.35
HRH1_CAVPO HRH1 Histamine H1 receptor 2.004e-08 0.50
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.036e-08 0.34
REV1_HUMAN REV1 DNA repair protein REV1 1.138e-07 0.28
PERM_HUMAN MPO Myeloperoxidase 2.184e-07 0.31
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 3.433e-07 0.50
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.006e-07 0.35
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 7.563e-06 0.32

Methyl_aminolevulinate

PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 2.343e-14 0.36
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 1.511e-10 0.31
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.884e-09 0.33
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.192e-07 0.32
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.379e-06 0.36
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.476e-06 0.36
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.845e-06 0.30
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 3.253e-06 0.30

Pentolinium

BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 2.3e-09 0.56
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 6.072e-07 0.31

Flucytosine

OXDA_RAT Dao D-amino-acid oxidase 1.623e-08 0.36
OXDA_PIG DAO D-amino-acid oxidase 1.3e-06 0.36

Oxamniquine

A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.423e-07 0.31
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.692e-06 0.30