Results of Job: search_088092ab-7043-4daa-88cd-1dc8d4ed8557

Query Target Key Target Name Description P-Value MaxTC

Triflupromazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.171e-176 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.331e-15 1.00
CHLE_HORSE BCHE Cholinesterase 3.433e-05 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 5.124e-05 1.00
PRIO_MOUSE Prnp Major prion protein 1.027e-86 0.70
LYSC1_RAT Lyz1 Lysozyme C-1 3.773e-53 0.67
TYTR_TRYCR TPR Trypanothione reductase 1.691e-52 0.70
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 5.116e-50 0.70
CALM_BOVIN CALM Calmodulin 6.46e-48 0.70
BGLR_RAT Gusb Beta-glucuronidase 5.837e-41 0.67
EBPL_HUMAN EBPL Emopamil-binding protein-like 5.837e-41 0.67
UTS2_RAT Uts2 Urotensin-2 3.56e-37 0.29
CALM1_HUMAN CALM1 Calmodulin-1 7.776e-36 0.70
Q76129_9HIV1 gag Structural capsid protein 7.263e-29 0.34
KCMA1_RAT Kcnma1 Calcium-activated potassium channel subunit alpha-1 3.331e-16 0.31
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.441e-16 0.71
Q9QXI6_MOUSE Slc5a1 SGLT1 protein 5.551e-16 0.35
HRH1_HUMAN HRH1 Histamine H1 receptor 4.974e-14 0.71
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 6.128e-14 0.70
NOX1_HUMAN NOX1 NADPH oxidase 1 1.178e-13 0.43
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.583e-13 0.46
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.872e-12 0.70
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 3.935e-12 0.33
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 6.269e-12 0.35
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.594e-11 0.33
HRH1_RAT Hrh1 Histamine H1 receptor 1.895e-11 0.71
HRH2_HUMAN HRH2 Histamine H2 receptor 6.389e-11 0.71
DRD5_HUMAN DRD5 D(1B) dopamine receptor 8.194e-11 0.70
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 1.302e-10 0.46
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 2.59e-10 0.36
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 5.42e-10 0.31
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 1.317e-09 0.40
PRIO_HUMAN PRNP Major prion protein 1.647e-09 0.71
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.009e-09 0.71
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.367e-09 0.71
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 2.614e-09 0.35
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.015e-09 0.71
ERG2_YEAST ERG2 C-8 sterol isomerase 1.006e-08 0.67
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.545e-08 0.71
WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.819e-08 0.67
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 2.554e-08 0.67
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.74e-08 0.71
TYTR_TRYBB TPR Trypanothione reductase 6.041e-08 0.46
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.255e-07 0.71
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.346e-07 0.30
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.779e-07 0.67
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.012e-07 0.71
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.176e-07 0.70
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 3.788e-07 0.33
CHLE_HUMAN BCHE Cholinesterase 6.629e-07 0.38
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.03e-06 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.63e-06 0.71
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.794e-06 0.71

Dextrothyroxine

SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 5.121e-61 1.00
NR1H4_HUMAN NR1H4 Bile acid receptor 0.01822 1.00
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 1.574e-157 0.74
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 4.563e-92 0.70
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 2.373e-69 0.38
TY3H_RAT Th Tyrosine 3-monooxygenase 7.025e-67 0.53
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.633e-55 0.41
Q9Z1J7_RAT Slc1a5 Amino acid transporter 3.543e-50 0.32
THB_RAT Thrb Thyroid hormone receptor beta 3.63e-49 0.74
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.123e-45 0.31
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 5.383e-44 0.33
MURI_LACFE murI Glutamate racemase 1.841e-40 0.32
BHMT2_HUMAN BHMT2 S-methylmethionine--homocysteine S-methyltransferase BHMT2 7.142e-37 0.29
KYNU_RAT Kynu Kynureninase 1.775e-36 0.29
GRM4_MOUSE Grm4 Metabotropic glutamate receptor 4 2.095e-36 0.29
THA_HUMAN THRA Thyroid hormone receptor alpha 1.251e-35 0.74
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 2.885e-35 0.37
TY3H_HUMAN TH Tyrosine 3-monooxygenase 4.962e-33 0.53
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 1.606e-32 0.32
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 4.945e-31 0.31
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 1.449e-29 0.33
THB_HUMAN THRB Thyroid hormone receptor beta 3.825e-29 0.74
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 4.301e-21 0.31
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 3.156e-20 0.31
GRIA2_RAT Gria2 Glutamate receptor 2 2.358e-19 0.39
GRIA1_MOUSE Gria1 Glutamate receptor 1 1.523e-18 0.29
GRIA3_RAT Gria3 Glutamate receptor 3 2.618e-18 0.35
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 7.502e-18 0.28
NEP_MOUSE Mme Neprilysin 2.431e-14 0.31
GLN1B_ECOLI glnA Glutamine synthetase 3.153e-14 0.31
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.87e-13 0.34
NOS2_RAT Nos2 Nitric oxide synthase, inducible 2.173e-13 0.29
KYNU_HUMAN KYNU Kynureninase 2.986e-13 0.29
GRIA3_HUMAN GRIA3 Glutamate receptor 3 5.423e-13 0.29
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 9.167e-13 0.31
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 3.302e-12 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 1.089e-11 0.31
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 1.538e-11 0.33
GRIA4_RAT Gria4 Glutamate receptor 4 7.056e-11 0.33
GRIA1_HUMAN GRIA1 Glutamate receptor 1 2.341e-09 0.33
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 3.061e-09 0.54
CSK_HUMAN CSK Tyrosine-protein kinase CSK 5.326e-09 0.53
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.367e-09 0.30
GRIA1_RAT Gria1 Glutamate receptor 1 2.444e-08 0.35
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.441e-07 0.29
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 4.973e-07 0.31
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 8.903e-07 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 5.096e-06 0.31
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 6.545e-06 0.36
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 7.112e-06 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 8.536e-06 0.29

Nitazoxanide

ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 0.04967 1.00
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 8.059e-46 0.35
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 2.784e-39 0.38
OGA_RAT Oga Protein O-GlcNAcase 6.048e-38 0.29
CFAD_RAT Cfd Complement factor D 1.609e-35 0.28
STIM1_RAT Stim1 Stromal interaction molecule 1 1.292e-30 0.36
MAP1_YEAST MAP1 Methionine aminopeptidase 1 2.825e-29 0.41
MAP1_ECOLI map Methionine aminopeptidase 1.493e-27 0.44
STIM1_HUMAN STIM1 Stromal interaction molecule 1 9.495e-20 0.36
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 1.762e-19 0.36
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.915e-18 0.30
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 5.905e-18 0.36
STXA_SHIDY stxA Shiga toxin subunit A 1.11e-16 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.331e-16 0.31
SENP8_HUMAN SENP8 Sentrin-specific protease 8 3.109e-15 0.36
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 4.885e-15 0.33
SENP6_HUMAN SENP6 Sentrin-specific protease 6 6.356e-13 0.36
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 1.615e-12 0.48
MITF_HUMAN MITF Microphthalmia-associated transcription factor 7.15e-12 0.38
CASP6_HUMAN CASP6 Caspase-6 7.225e-12 0.50
CCNK_HUMAN CCNK Cyclin-K 1.615e-11 0.31
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 2.617e-11 0.32
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 4.959e-11 0.30
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 1.447e-10 0.32
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.261e-10 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 5.662e-10 0.38
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 6.557e-10 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.236e-08 0.35
METC_ECOLI metC Cystathionine beta-lyase MetC 1.106e-07 0.30
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.248e-07 0.33
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.992e-07 0.50
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 2.442e-07 0.48
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 4.044e-07 0.34
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 5.06e-07 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 5.199e-07 0.35
LUCI_PHOPY Luciferin 4-monooxygenase 5.294e-07 0.49
BRPF1_HUMAN BRPF1 Peregrin 5.352e-07 0.30
WDR5_HUMAN WDR5 WD repeat-containing protein 5 5.767e-07 0.30
Q9BRH5_HUMAN DGAT1 DGAT1 protein 7.834e-07 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 8.184e-07 0.36
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.634e-06 0.29
HXK4_HUMAN GCK Hexokinase-4 2.196e-06 0.33
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 2.212e-06 0.42
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.386e-06 0.31
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 5.411e-06 0.29
LUCI_AQULA Luciferin 4-monooxygenase 8.558e-06 0.28
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 9.397e-06 0.34

Acetyldigitoxin

NOTC1_MOUSE Notch1 Neurogenic locus notch homolog protein 1 2.318e-149 0.82
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 6.531e-132 0.84
AT1A1_HUMAN ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 8.051e-105 0.68
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 3.153e-96 0.68
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 4.497e-87 0.68
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 2.514e-79 0.84
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 1.75e-60 0.58
AT1A1_PIG ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 8.076e-55 0.37
AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 6.121e-54 0.43
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 3.47e-45 0.68
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 3.47e-45 0.68
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 1.375e-34 0.43
IF4A1_MOUSE Eif4a1 Eukaryotic initiation factor 4A-I 2.496e-31 0.32
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 3.002e-30 0.68
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 5.688e-18 0.47
PAX8_HUMAN PAX8 Paired box protein Pax-8 2.436e-08 0.80
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.115e-06 0.43