Results of Job: search_0acad39c-e0bd-433b-9a51-dbbcaf97d74f

Query Target Key Target Name Description P-Value MaxTC

compound_1

EGFR_HUMAN EGFR Epidermal growth factor receptor 3.821e-224 0.49
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 4.29e-210 0.49
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 8.303e-137 0.37
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 5.405e-118 0.39
AURKA_HUMAN AURKA Aurora kinase A 1.742e-111 0.49
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.963e-110 0.44
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.535e-104 0.49
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.969e-89 0.38
AURKB_HUMAN AURKB Aurora kinase B 6.807e-72 0.46
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.996e-71 0.45
SHH_MOUSE Shh Sonic hedgehog protein 5.247e-62 0.40
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 4.002e-58 0.33
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.171e-53 0.45
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 3.861e-51 0.39
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 8.701e-49 0.39
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.2e-47 0.33
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 1.094e-46 0.29
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.396e-46 0.32
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.826e-45 0.34
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 2.597e-44 0.35
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.509e-42 0.40
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 8.965e-42 0.37
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 8.432e-41 0.32
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.918e-39 0.40
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 3.236e-37 0.32
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 2.58e-35 0.39
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 5.964e-33 0.37
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 6.793e-33 0.37
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.394e-31 0.33
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 4.731e-29 0.32
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 9.717e-29 0.33
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 3.595e-26 0.32
LCK_HUMAN LCK Tyrosine-protein kinase Lck 5.662e-26 0.46
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 6.056e-26 0.38
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 8.187e-26 0.38
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.078e-25 0.35
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 1.361e-25 0.33
TPOR_HUMAN MPL Thrombopoietin receptor 1.316e-24 0.33
AUKBA_XENLA aurkb-a Aurora kinase B-A 9.748e-24 0.38
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.53e-23 0.30
ENL_HUMAN MLLT1 Protein ENL 2.117e-23 0.29
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.714e-23 0.33
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.594e-21 0.41
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 5.124e-20 0.33
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.12e-19 0.33
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 4.69e-19 0.35
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.499e-18 0.31
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 2.446e-18 0.29
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 2.446e-18 0.29
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 2.451e-18 0.33
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.115e-18 0.46
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 1.006e-17 0.28
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.478e-17 0.32
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 2.533e-17 0.33
HPSE_HUMAN HPSE Heparanase 2.802e-17 0.35
LUCI_RENRE Coelenterazine h 2-monooxygenase 1.11e-16 0.31
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.11e-16 0.37
CTRO_HUMAN CIT Citron Rho-interacting kinase 2.22e-16 0.33
MET_HUMAN MET Hepatocyte growth factor receptor 2.22e-16 0.38
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.22e-16 0.39
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 3.331e-16 0.31
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 3.331e-16 0.33
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.331e-16 0.37
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 5.551e-16 0.35
PTGES_HUMAN PTGES Prostaglandin E synthase 9.992e-16 0.33
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 9.992e-16 0.35
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 4.33e-15 0.37
BKRB2_CAVPO BDKRB2 B2 bradykinin receptor 4.996e-15 0.33
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 6.772e-15 0.36
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.388e-14 0.33
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 1.577e-14 0.29
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 3.597e-14 0.33
OPRX_HUMAN OPRL1 Nociceptin receptor 3.941e-14 0.39
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 6.206e-14 0.35
SMO_HUMAN SMO Smoothened homolog 7.96e-14 0.40
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.167e-13 0.40
AURKA_MOUSE Aurka Aurora kinase A 1.426e-13 0.30
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1.502e-13 0.33
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.608e-13 0.33
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 1.704e-13 0.29
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 3.684e-13 0.36
INSR_HUMAN INSR Insulin receptor 3.908e-13 0.41
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 5.06e-13 0.37
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 5.6e-13 0.35
PRIO_SHEEP PRNP Major prion protein 1.319e-12 0.32
PSBA_SPIOL psbA Photosystem II protein D1 1.849e-12 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.889e-12 0.41
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.917e-12 0.32
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 2.246e-12 0.30
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 2.325e-12 0.33
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 2.903e-12 0.33
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 3.45e-12 0.31
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.171e-12 0.39
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 4.437e-12 0.33
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 4.673e-12 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 7.885e-12 0.33
HCK_HUMAN HCK Tyrosine-protein kinase HCK 8.401e-12 0.33
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 8.472e-12 0.33
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.372e-11 0.36
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.578e-11 0.33
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 1.852e-11 0.33
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.437e-11 0.35
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 3.398e-11 0.31
RXFP1_HUMAN RXFP1 Relaxin receptor 1 3.474e-11 0.31
BKRB2_HUMAN BDKRB2 B2 bradykinin receptor 3.48e-11 0.33
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 4.238e-11 0.38
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 4.248e-11 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 4.515e-11 0.32
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 5.907e-11 0.29
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 6.433e-11 0.32
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 6.502e-11 0.33
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 6.626e-11 0.29
FA5_HUMAN F5 Coagulation factor V 8.739e-11 0.29
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 9.175e-11 0.38
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 1.203e-10 0.30
Q9Z1J7_RAT Slc1a5 Amino acid transporter 1.415e-10 0.31
PTGES_CANLF PTGES Prostaglandin E synthase 1.539e-10 0.28
DMPK_HUMAN DMPK Myotonin-protein kinase 1.866e-10 0.33
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 2.504e-10 0.39
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 2.715e-10 0.33
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.987e-10 0.28
PCKGC_HUMAN PCK1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 3.101e-10 0.28
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 3.322e-10 0.33
SCAF_HCMVA UL80 Capsid scaffolding protein 5.638e-10 0.37
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 7.91e-10 0.33
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8.145e-10 0.33
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.02e-09 0.32
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.246e-09 0.37
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 1.292e-09 0.32
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.419e-09 0.36
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.537e-09 0.33
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 2.261e-09 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.993e-09 0.40
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 3.723e-09 0.33
SYUA_HUMAN SNCA Alpha-synuclein 3.912e-09 0.31
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 4.038e-09 0.30
PCKGC_RAT Pck1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.864e-09 0.28
GAK_HUMAN GAK Cyclin-G-associated kinase 4.993e-09 0.33
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 5.747e-09 0.35
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 6.793e-09 0.33
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 6.89e-09 0.29
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 8.048e-09 0.29
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.005e-08 0.40
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 1.082e-08 0.29
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 1.124e-08 0.33
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.344e-08 0.30
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.526e-08 0.38
LIMK1_RAT Limk1 LIM domain kinase 1 1.751e-08 0.28
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.064e-08 0.32
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 2.84e-08 0.33
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.882e-08 0.33
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 3.013e-08 0.41
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 3.102e-08 0.34
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 3.436e-08 0.29
CYB_PIG MT-CYB Cytochrome b 3.585e-08 0.29
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 3.899e-08 0.34
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 6.612e-08 0.33
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 6.637e-08 0.29
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 7.347e-08 0.31
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 7.347e-08 0.31
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 8.472e-08 0.31
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 8.854e-08 0.32
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.098e-07 0.31
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.109e-07 0.33
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 1.144e-07 0.28
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.224e-07 0.33
IL6_HUMAN IL6 Interleukin-6 1.255e-07 0.30
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.744e-07 0.32
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.892e-07 0.35
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.947e-07 0.29
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.058e-07 0.34
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 2.234e-07 0.30
O61059_LEIME LmGT2 Glucose transporter 2.365e-07 0.35
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 2.48e-07 0.33
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 2.62e-07 0.33
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.666e-07 0.35
BTK_HUMAN BTK Tyrosine-protein kinase BTK 3.052e-07 0.38
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 3.983e-07 0.29
EGFR_MOUSE Egfr Epidermal growth factor receptor 4.514e-07 0.29
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.284e-07 0.30
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 6.072e-07 0.31
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 6.423e-07 0.29
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 6.489e-07 0.33
HDAC6_HUMAN HDAC6 Histone deacetylase 6 6.76e-07 0.41
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 7.457e-07 0.37
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 7.518e-07 0.29
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 8.392e-07 0.33
AURKC_HUMAN AURKC Aurora kinase C 8.446e-07 0.33
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 9.529e-07 0.33
O97467_PLAFA ht1 Hexose transporter 1 1.107e-06 0.35
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.289e-06 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.507e-06 0.30
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 1.79e-06 0.33
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 2.006e-06 0.29
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2.156e-06 0.28
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.381e-06 0.37
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 2.495e-06 0.32
P2RX3_HUMAN P2RX3 P2X purinoceptor 3 3.021e-06 0.37
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.163e-06 0.33
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.208e-06 0.35
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 3.278e-06 0.29
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 3.43e-06 0.40
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 3.816e-06 0.33
RON_HUMAN MST1R Macrophage-stimulating protein receptor 4.636e-06 0.33
INSRR_HUMAN INSRR Insulin receptor-related protein 5.133e-06 0.29
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 5.133e-06 0.29
SKN1_CAEEL skn-1 Protein skinhead-1 5.188e-06 0.36
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 5.358e-06 0.33
Q76129_9HIV1 gag Structural capsid protein 5.471e-06 0.29
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 5.598e-06 0.38
NR1H4_HUMAN NR1H4 Bile acid receptor 5.787e-06 0.31
FRK_HUMAN FRK Tyrosine-protein kinase FRK 5.956e-06 0.33
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 6.128e-06 0.30
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 6.2e-06 0.37
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 6.49e-06 0.29
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 6.573e-06 0.38
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 7.497e-06 0.33
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 8.066e-06 0.33
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 8.07e-06 0.37
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 8.64e-06 0.35
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 8.752e-06 0.34
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 9.449e-06 0.31
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 9.761e-06 0.33
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 9.822e-06 0.31