Results of Job: search_1951a0be-d9d3-4785-810e-8dc540700428

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 1.551e-139 0.55
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 2.38e-90 0.48
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.767e-81 0.36
C3SLB7_ECOLX glmU Bifunctional protein GlmU 2.023e-77 0.42
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 3.095e-64 0.39
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 6.61e-63 0.35
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.745e-57 0.38
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 1.089e-50 0.32
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.009e-50 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 4.71e-43 0.39
Q8IL11_PLAF7 M17 leucyl aminopeptidase 2.423e-40 0.41
TLR4_MOUSE Tlr4 Toll-like receptor 4 4.836e-39 0.36
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.938e-38 0.39
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 2.46e-37 0.42
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 7.222e-36 0.32
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.493e-35 0.40
SHH_MOUSE Shh Sonic hedgehog protein 5.863e-33 0.34
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.758e-32 0.31
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.951e-31 0.33
PRIO_HUMAN PRNP Major prion protein 7.441e-31 0.37
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 4.952e-30 0.39
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 4.953e-29 0.39
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.256e-29 0.38
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 1.581e-28 0.29
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 2.132e-27 0.40
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.168e-25 0.32
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 1.246e-25 0.32
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.392e-24 0.37
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 7.095e-24 0.37
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.409e-23 0.38
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.424e-23 0.34
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.338e-22 0.36
TLR4_HUMAN TLR4 Toll-like receptor 4 2.156e-22 0.36
ATM_HUMAN ATM Serine-protein kinase ATM 9.738e-22 0.33
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 5.165e-21 0.30
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 5.679e-21 0.30
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 9.663e-21 0.29
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.878e-20 0.33
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 3.762e-20 0.32
KC1D_RAT Csnk1d Casein kinase I isoform delta 5.209e-20 0.37
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 5.661e-20 0.37
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 6.628e-20 0.38
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.005e-19 0.35
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 8.139e-19 0.34
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.448e-18 0.45
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.651e-18 0.34
PRIO_SHEEP PRNP Major prion protein 2.077e-18 0.32
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.066e-18 0.31
LIPL_HUMAN LPL Lipoprotein lipase 3.809e-18 0.29
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 5.694e-18 0.45
O31272_9GAMM imiS Beta-lactamase 1.316e-17 0.29
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 3.41e-17 0.43
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.11e-16 0.39
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 2.22e-16 0.34
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 6.661e-16 0.31
PANK1_HUMAN PANK1 Pantothenate kinase 1 9.992e-16 0.30
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.443e-15 0.43
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.665e-15 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.665e-15 0.29
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 2.22e-15 0.33
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.664e-15 0.42
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.661e-15 0.35
HPSE_HUMAN HPSE Heparanase 1.787e-14 0.34
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 2.154e-14 0.29
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.354e-14 0.39
TSHR_HUMAN TSHR Thyrotropin receptor 4.841e-14 0.32
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 7.516e-14 0.44
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 8.66e-14 0.32
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 2.151e-13 0.32
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.156e-13 0.33
Q9NBA7_PLAFA Cysteine protease falcipain-3 2.23e-13 0.36
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 2.788e-13 0.29
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 3.451e-13 0.32
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.284e-13 0.34
MET_MOUSE Met Hepatocyte growth factor receptor 5.222e-13 0.28
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 5.397e-13 0.34
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 6.057e-13 0.30
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 7.558e-13 0.36
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.276e-12 0.38
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.189e-12 0.38
AURKA_HUMAN AURKA Aurora kinase A 3.248e-12 0.42
SMO_MOUSE Smo Smoothened homolog 6.616e-12 0.35
PA21B_HUMAN PLA2G1B Phospholipase A2 6.657e-12 0.44
RON_HUMAN MST1R Macrophage-stimulating protein receptor 7.431e-12 0.37
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.488e-11 0.37
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.435e-11 0.30
FA7_HUMAN F7 Coagulation factor VII 3.168e-11 0.35
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 4.39e-11 0.36
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 4.449e-11 0.34
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 5.189e-11 0.36
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.631e-11 0.34
A5H660_SCHMA HDAC8 Histone deacetylase 8 7.791e-11 0.30
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 8.927e-11 0.45
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.204e-10 0.30
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.397e-10 0.33
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 5.866e-10 0.33
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 7.012e-10 0.33
CHLE_HUMAN BCHE Cholinesterase 8.165e-10 0.31
S100B_HUMAN S100B Protein S100-B 9.638e-10 0.28
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 1.007e-09 0.35
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 1.129e-09 0.34
ACES_ELEEL ache Acetylcholinesterase 1.165e-09 0.33
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.292e-09 0.38
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.45e-09 0.29
AURKB_HUMAN AURKB Aurora kinase B 1.679e-09 0.42
MEP50_HUMAN WDR77 Methylosome protein 50 1.896e-09 0.32
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.309e-09 0.34
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.371e-09 0.32
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 2.992e-09 0.35
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 3.164e-09 0.32
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 4.708e-09 0.33
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 5.927e-09 0.38
HDAC1_MOUSE Hdac1 Histone deacetylase 1 7.397e-09 0.30
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.028e-08 0.35
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.136e-08 0.32
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.764e-08 0.33
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.906e-08 0.39
DRD1_PIG DRD1 D(1A) dopamine receptor 1.933e-08 0.30
HSF1_MOUSE Hsf1 Heat shock factor protein 1 2.289e-08 0.41
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 2.987e-08 0.29
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 3.426e-08 0.37
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 4.045e-08 0.34
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 6.242e-08 0.33
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 7.612e-08 0.36
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 7.677e-08 0.33
ACES_TETCF ache Acetylcholinesterase 8.277e-08 0.31
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 9.06e-08 0.43
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 1.113e-07 0.36
KISSR_HUMAN KISS1R KiSS-1 receptor 1.185e-07 0.32
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.327e-07 0.40
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 1.328e-07 0.30
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.557e-07 0.33
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.798e-07 0.31
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.89e-07 0.38
ACES_HUMAN ACHE Acetylcholinesterase 2.046e-07 0.32
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.386e-07 0.34
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.575e-07 0.28
RECA_MYCTU recA Protein RecA 3.52e-07 0.39
TERT_HUMAN TERT Telomerase reverse transcriptase 4.012e-07 0.30
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 4.395e-07 0.30
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 5.11e-07 0.28
XBP1_HUMAN XBP1 X-box-binding protein 1 5.265e-07 0.36
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 6.245e-07 0.33
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 7.849e-07 0.29
CTNB1_HUMAN CTNNB1 Catenin beta-1 8.855e-07 0.34
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 1.106e-06 0.28
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.246e-06 0.38
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.358e-06 0.30
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.375e-06 0.38
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.595e-06 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.598e-06 0.33
KLK7_HUMAN KLK7 Kallikrein-7 1.761e-06 0.38
SMO_HUMAN SMO Smoothened homolog 1.787e-06 0.30
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.09e-06 0.31
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 2.188e-06 0.35
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 2.344e-06 0.30
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.769e-06 0.41
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.18e-06 0.37
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 3.244e-06 0.30
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.272e-06 0.28
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 3.279e-06 0.33
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 3.422e-06 0.31
KHK_HUMAN KHK Ketohexokinase 3.523e-06 0.31
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 3.815e-06 0.32
DPOL_VACCW POL DNA polymerase 4.125e-06 0.30
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.173e-06 0.38
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 4.734e-06 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.118e-06 0.37
DNAB_MYCTU dnaB Replicative DNA helicase 5.444e-06 0.39
TNFA_HUMAN TNF Tumor necrosis factor 6.204e-06 0.34
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.299e-06 0.32
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.584e-06 0.32
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 7.529e-06 0.36
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 8.162e-06 0.34
HDAC6_HUMAN HDAC6 Histone deacetylase 6 8.848e-06 0.32
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 9.225e-06 0.31