Results of Job: search_1e9f6251-f655-42a0-8c4c-7478656a5329

Query Target Key Target Name Description P-Value MaxTC

compound_1

DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 2.884e-92 0.77
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 8.146e-88 0.72
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.938e-77 0.75
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 7.398e-73 0.58
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.731e-70 0.59
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 6.262e-69 0.37
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 7.218e-66 0.41
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.563e-64 0.51
VDR_RAT Vdr Vitamin D3 receptor 2.72e-61 0.34
CP125_MYCTU cyp125 Steroid C26-monooxygenase 2.316e-60 0.76
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 5.213e-59 0.74
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.539e-58 0.77
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.716e-49 0.40
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 4.247e-49 0.51
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.246e-47 0.57
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.144e-45 0.59
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 4.868e-44 0.39
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 1.129e-41 0.53
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.882e-41 0.35
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.964e-40 0.57
VDR_PIG VDR Vitamin D3 receptor 1.921e-39 0.31
VTDB_HUMAN GC Vitamin D-binding protein 1.921e-39 0.31
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 8.437e-39 0.63
VDRA_DANRE vdra Vitamin D3 receptor A 1.876e-38 0.31
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.634e-36 0.45
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 3.875e-36 0.29
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 5.926e-33 0.47
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.209e-29 0.38
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.16e-28 0.40
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.824e-27 0.60
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.052e-26 0.83
VDR_HUMAN VDR Vitamin D3 receptor 1.414e-26 0.42
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 2.384e-26 0.38
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 1.382e-25 0.32
VDR_CHICK VDR Vitamin D3 receptor 4.256e-24 0.31
ERG2_YEAST ERG2 C-8 sterol isomerase 1.828e-21 0.42
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.886e-21 0.57
NR1H4_HUMAN NR1H4 Bile acid receptor 4.326e-20 0.42
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 3.119e-19 0.37
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.122e-19 0.31
ESR2_HUMAN ESR2 Estrogen receptor beta 2.568e-18 0.52
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 3.956e-18 0.30
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 6.556e-18 0.28
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 7.773e-18 0.28
ANDR_HUMAN AR Androgen receptor 1.785e-17 0.52
ECR_DROME EcR Ecdysone receptor 5.288e-17 0.32
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.22e-16 0.56
RORA_HUMAN RORA Nuclear receptor ROR-alpha 9.992e-16 0.53
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 4.33e-15 0.74
REST_BORBU resT Telomere resolvase ResT 7.105e-15 0.37
ABCBB_HUMAN ABCB11 Bile salt export pump 9.104e-15 0.36
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 9.881e-15 0.31
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.621e-14 0.33
ANDR_RAT Ar Androgen receptor 2.52e-14 0.35
ESR1_HUMAN ESR1 Estrogen receptor 4.685e-13 0.52
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 9.012e-13 0.53
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.707e-12 0.53
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.387e-12 0.46
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.525e-12 0.53
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.525e-12 0.53
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.589e-11 0.53
SHH_MOUSE Shh Sonic hedgehog protein 1.934e-11 0.63
CP19A_HUMAN CYP19A1 Aromatase 6.443e-11 0.58
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 6.457e-11 0.53
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 6.457e-11 0.53
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.883e-11 0.53
VDR_BOVIN VDR Vitamin D3 receptor 1.068e-10 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.366e-10 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.485e-10 0.53
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.763e-10 0.38
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.793e-10 0.57
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 5.881e-10 0.35
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.98e-10 0.53
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.114e-09 0.33
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.37e-09 0.30
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.863e-09 0.30
GLI1_HUMAN GLI1 Zinc finger protein GLI1 4.926e-09 0.32
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.633e-09 0.53
FGF1_HUMAN FGF1 Fibroblast growth factor 1 8.815e-09 0.29
DPOLB_RAT Polb DNA polymerase beta 1.197e-08 0.42
ANDR_MOUSE Ar Androgen receptor 7.635e-08 0.33
Q690N0_BOVIN PGR Progesterone receptor 8.694e-08 0.33
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 9.412e-08 0.30
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.052e-07 0.74
RORG_HUMAN RORC Nuclear receptor ROR-gamma 3.219e-07 0.83
SHH_HUMAN SHH Sonic hedgehog protein 3.277e-07 0.32
HRH3_RAT Hrh3 Histamine H3 receptor 8.224e-07 0.35
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.312e-06 0.52
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.507e-06 0.30
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 3.029e-06 0.38
IL2_HUMAN IL2 Interleukin-2 4.27e-06 0.32
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 4.931e-06 0.50
CEGT_HUMAN UGCG Ceramide glucosyltransferase 8.694e-06 0.50