Results of Job: search_206b2ad2-fb20-45e6-b011-de4a0e335064

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 3.093e-195 0.65
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 7.342e-93 0.36
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 3.219e-86 0.49
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 2.783e-67 0.39
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.808e-61 0.33
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.164e-55 0.36
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 7.542e-51 0.32
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.248e-49 0.41
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 6.683e-42 0.33
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 9.791e-41 0.48
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.302e-39 0.32
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 6.054e-39 0.33
TLR4_MOUSE Tlr4 Toll-like receptor 4 2.586e-38 0.36
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.11e-37 0.44
VDAC2_HUMAN VDAC2 Voltage-dependent anion-selective channel protein 2 1.046e-36 0.29
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 3.875e-36 0.29
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.551e-34 0.33
PRIO_HUMAN PRNP Major prion protein 4.987e-32 0.50
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 7.742e-31 0.35
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 2.142e-30 0.30
SHH_MOUSE Shh Sonic hedgehog protein 6.077e-30 0.34
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 9.631e-30 0.38
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 9.839e-30 0.31
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 1.073e-29 0.32
AXIN2_HUMAN AXIN2 Axin-2 4.62e-29 0.29
ATS1_HUMAN ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1 7.659e-29 0.28
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 4.585e-28 0.32
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 6.144e-28 0.40
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 8.267e-27 0.32
Q38C41_TRYB2 Phosphotransferase 2.977e-24 0.39
AL5AP_RAT Alox5ap Arachidonate 5-lipoxygenase-activating protein 3.169e-24 0.30
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 3.516e-24 0.30
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.733e-24 0.32
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 9.728e-24 0.30
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.239e-23 0.49
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.333e-23 0.42
KC1D_RAT Csnk1d Casein kinase I isoform delta 1.851e-23 0.36
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 4.08e-22 0.40
TLR4_HUMAN TLR4 Toll-like receptor 4 7.973e-22 0.36
WNT3A_MOUSE Wnt3a Protein Wnt-3a 1.079e-20 0.30
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 1.22e-20 0.34
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.732e-20 0.41
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 8.212e-20 0.37
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 8.452e-20 0.47
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.531e-19 0.35
NTR2_RAT Ntsr2 Neurotensin receptor type 2 2.729e-19 0.33
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 2.752e-19 0.44
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.805e-19 0.39
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 2.912e-19 0.48
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 3.007e-19 0.32
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 6.252e-19 0.35
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 7.905e-19 0.30
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.497e-19 0.33
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.023e-18 0.49
KLK14_HUMAN KLK14 Kallikrein-14 2.139e-18 0.29
NMT2_HUMAN NMT2 Glycylpeptide N-tetradecanoyltransferase 2 3.886e-18 0.29
Q8IL11_PLAF7 M17 leucyl aminopeptidase 1.624e-17 0.38
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 2.165e-17 0.38
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.11e-16 0.47
PANC_MYCTU panC Pantothenate synthetase 1.11e-16 0.33
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.11e-16 0.32
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 2.22e-16 0.31
NDKB_HUMAN NME2 Nucleoside diphosphate kinase B 3.331e-16 0.28
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.11e-15 0.40
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.11e-15 0.35
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 1.443e-15 0.39
AA2AR_RAT Adora2a Adenosine receptor A2a 1.665e-15 0.39
MK08_RAT Mapk8 Mitogen-activated protein kinase 8 3.22e-15 0.28
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 5.218e-15 0.38
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 9.104e-15 0.35
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.643e-14 0.46
SYUA_HUMAN SNCA Alpha-synuclein 1.643e-14 0.34
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.298e-14 0.31
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 4.163e-14 0.29
PA21B_HUMAN PLA2G1B Phospholipase A2 4.441e-14 0.44
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.94e-14 0.31
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 5.007e-14 0.41
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 5.185e-14 0.34
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 9.825e-14 0.35
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.056e-13 0.34
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.383e-13 0.30
AA1R_RAT Adora1 Adenosine receptor A1 1.478e-13 0.39
GRP3_HUMAN RASGRP3 Ras guanyl-releasing protein 3 2.039e-13 0.30
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.156e-13 0.29
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 5.846e-13 0.32
MET_MOUSE Met Hepatocyte growth factor receptor 6.108e-13 0.28
STRP_STRP1 ska Streptokinase A 1.434e-12 0.41
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 2.303e-12 0.36
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 2.916e-12 0.39
SENP1_HUMAN SENP1 Sentrin-specific protease 1 6.561e-12 0.29
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.937e-11 0.35
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 5.329e-11 0.29
Q9NBA7_PLAFA Cysteine protease falcipain-3 5.329e-11 0.29
MEP50_HUMAN WDR77 Methylosome protein 50 5.815e-11 0.38
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 7.529e-11 0.38
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 8.931e-11 0.36
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 9.54e-11 0.41
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 1.079e-10 0.35
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 1.085e-10 0.31
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.105e-10 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 1.186e-10 0.30
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 1.289e-10 0.28
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 2.19e-10 0.32
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 3.414e-10 0.38
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 3.67e-10 0.32
ACES_BOVIN ACHE Acetylcholinesterase 5.556e-10 0.32
MC4R_HUMAN MC4R Melanocortin receptor 4 7.23e-10 0.37
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 8.436e-10 0.31
H9B8T9_CAPHI CTSB Cathepsin B 1.081e-09 0.31
TYTR_TRYCR TPR Trypanothione reductase 1.192e-09 0.35
KLK7_HUMAN KLK7 Kallikrein-7 1.348e-09 0.42
ANDR_MOUSE Ar Androgen receptor 1.354e-09 0.29
V1BR_RAT Avpr1b Vasopressin V1b receptor 2.627e-09 0.32
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 2.92e-09 0.32
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 4.609e-09 0.32
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 5.977e-09 0.38
DYR_HUMAN DHFR Dihydrofolate reductase 6.065e-09 0.33
CNR1_HUMAN CNR1 Cannabinoid receptor 1 6.539e-09 0.36
RCE1_YEAST RCE1 CAAX prenyl protease 2 7.463e-09 0.35
PERM_HUMAN MPO Myeloperoxidase 7.471e-09 0.32
KLF5_HUMAN KLF5 Krueppel-like factor 5 7.476e-09 0.32
EGLN2_HUMAN EGLN2 Egl nine homolog 2 1.089e-08 0.31
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.183e-08 0.29
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.237e-08 0.34
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.884e-08 0.39
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 1.965e-08 0.32
GRIA1_RAT Gria1 Glutamate receptor 1 1.987e-08 0.37
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.408e-08 0.31
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.855e-08 0.32
CHLE_HUMAN BCHE Cholinesterase 2.882e-08 0.37
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3.394e-08 0.31
RASH_HUMAN HRAS GTPase HRas 3.506e-08 0.30
TSPO_RAT Tspo Translocator protein 4.068e-08 0.35
AA1R_BOVIN ADORA1 Adenosine receptor A1 4.831e-08 0.40
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 6.171e-08 0.40
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 7.005e-08 0.34
ACES_HUMAN ACHE Acetylcholinesterase 7.633e-08 0.37
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 8.171e-08 0.38
PPGB_HUMAN CTSA Lysosomal protective protein 8.381e-08 0.31
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 1.156e-07 0.30
JUN_HUMAN JUN Transcription factor AP-1 1.169e-07 0.36
BGLR_HUMAN GUSB Beta-glucuronidase 1.217e-07 0.30
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.317e-07 0.31
E3UJZ5_SPOLI Ecdysone receptor 1.379e-07 0.30
LUCI_PHOPY Luciferin 4-monooxygenase 1.412e-07 0.41
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 1.412e-07 0.30
RECA_MYCTU recA Protein RecA 1.475e-07 0.35
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.531e-07 0.29
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 1.542e-07 0.32
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.654e-07 0.51
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.722e-07 0.32
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.864e-07 0.35
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 1.953e-07 0.32
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.305e-07 0.34
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.322e-07 0.46
CHLE_HORSE BCHE Cholinesterase 2.33e-07 0.37
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 2.745e-07 0.32
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.824e-07 0.28
ACES_ELEEL ache Acetylcholinesterase 3.305e-07 0.37
EGLN1_HUMAN EGLN1 Egl nine homolog 1 3.465e-07 0.33
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 3.647e-07 0.32
TSHR_HUMAN TSHR Thyrotropin receptor 3.709e-07 0.30
PRIO_SHEEP PRNP Major prion protein 4.114e-07 0.33
MMP13_HUMAN MMP13 Collagenase 3 4.191e-07 0.36
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.987e-07 0.34
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5e-07 0.35
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 6.517e-07 0.33
XBP1_HUMAN XBP1 X-box-binding protein 1 7.004e-07 0.37
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.237e-07 0.38
HRP1_PLAFA Histidine-rich protein PFHRP-II 7.622e-07 0.36
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 8.195e-07 0.34
LIPS_RAT Lipe Hormone-sensitive lipase 8.726e-07 0.35
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.011e-06 0.31
CCKAR_RAT Cckar Cholecystokinin receptor type A 1.159e-06 0.37
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 1.162e-06 0.34
LUCI_AQULA Luciferin 4-monooxygenase 1.203e-06 0.33
FA10_HUMAN F10 Coagulation factor X 1.334e-06 0.34
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 1.364e-06 0.39
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 1.398e-06 0.32
HSF1_MOUSE Hsf1 Heat shock factor protein 1 1.551e-06 0.38
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.567e-06 0.30
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.597e-06 0.36
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 1.648e-06 0.32
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 1.788e-06 0.30
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 1.924e-06 0.35
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 2.032e-06 0.29
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 2.035e-06 0.34
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 2.175e-06 0.31
KLK5_HUMAN KLK5 Kallikrein-5 2.185e-06 0.29
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.363e-06 0.30
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.423e-06 0.31
GLR_HUMAN GCGR Glucagon receptor 2.873e-06 0.32
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.103e-06 0.33
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.326e-06 0.32
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.483e-06 0.32
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 3.52e-06 0.31
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 3.924e-06 0.34
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 4.075e-06 0.28
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 4.496e-06 0.32
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 4.749e-06 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.869e-06 0.34
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.19e-06 0.35
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 5.59e-06 0.32
Q8MWR1_SPOFR USP Ultraspiracle protein 5.668e-06 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 5.668e-06 0.30
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 6.395e-06 0.33
Q76353_9HIV1 Integrase 7.059e-06 0.43
AGP1_YEAST AGP1 General amino acid permease AGP1 7.705e-06 0.28
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 7.73e-06 0.31
ECR_BOMMO EcR Ecdysone receptor 9.176e-06 0.30
HRH3_HUMAN HRH3 Histamine H3 receptor 9.961e-06 0.39