Results of Job: search_24ad83da-67dd-4a91-86c7-86148fe43082

Query Target Key Target Name Description P-Value MaxTC

Cycloguanil

DYR_CHICK DHFR Dihydrofolate reductase 9.283e-248 1.00
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 1.677e-96 1.00
DYR_PNECA Dihydrofolate reductase 8.289e-32 1.00
DYR_HUMAN DHFR Dihydrofolate reductase 1.11e-16 1.00
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 2.72e-14 1.00
DYR_RAT Dhfr Dihydrofolate reductase 0.03909 1.00
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.229e-127 0.68
DYR_ECOLI folA Dihydrofolate reductase 7.512e-70 0.71
Q8I1R6_PLAF7 Bifunctional dihydrofolate reductase-thymidylate synthase 3.077e-50 0.40
DYR_LACCA folA Dihydrofolate reductase 3.36e-49 0.62
DYR_BOVIN DHFR Dihydrofolate reductase 5.398e-12 0.40

Larotrectinib

NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 5.116e-154 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 1.95e-06 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 2.916e-05 1.00
ALBU_BOVIN ALB Serum albumin 3.093e-30 0.32
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 2.043e-17 0.33
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 2.087e-14 0.29
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 9.42e-09 0.36
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.137e-08 0.29
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 4.909e-08 0.64
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 2.786e-07 0.31
GYRB_MYCS2 gyrB DNA gyrase subunit B 7.955e-07 0.29
S1PR2_RAT S1pr2 Sphingosine 1-phosphate receptor 2 1.263e-06 0.32
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 4.749e-06 0.30

Vibegron

ADRB3_MACMU ADRB3 Beta-3 adrenergic receptor 2.745e-135 1.00
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.523e-48 1.00
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 8.795e-47 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.374e-37 1.00
ISPT_STRPN uppS Isoprenyl transferase 1.02e-66 0.38
ITB1_HUMAN ITGB1 Integrin beta-1 9.818e-25 0.38
ITA4_HUMAN ITGA4 Integrin alpha-4 2.591e-24 0.38
NMDE2_MOUSE Grin2b Glutamate receptor ionotropic, NMDA 2B 3.925e-17 0.30
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.585e-09 0.52
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.767e-08 0.30
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.006e-07 0.30
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 2.438e-07 0.32
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 8.182e-07 0.57
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 3.454e-06 0.34

Zanubrutinib

BTK_HUMAN BTK Tyrosine-protein kinase BTK 8.932e-132 1.00
PXL2A_HUMAN PRXL2A Peroxiredoxin-like 2A 9.086e-59 0.47
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 1.101e-30 0.35
LCK_HUMAN LCK Tyrosine-protein kinase Lck 5.89e-20 0.47
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.11e-16 0.47
TEC_HUMAN TEC Tyrosine-protein kinase Tec 1.11e-16 0.47
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 4.441e-16 0.34
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.776e-12 0.47
Q8MMZ4_PLAFA cGMP-dependent protein kinase 1.537e-11 0.28
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 1.615e-11 0.47
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.339e-09 0.47
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.744e-09 0.31
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 6.868e-09 0.33
TGM1_HUMAN TGM1 Protein-glutamine gamma-glutamyltransferase K 3.964e-08 0.33
EGFR_HUMAN EGFR Epidermal growth factor receptor 6.238e-08 0.53
Q25615_ONCVO Chitinase 2.26e-07 0.30
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 3.583e-07 0.47
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 5.914e-07 0.47
F13A_HUMAN F13A1 Coagulation factor XIII A chain 1.978e-06 0.33
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 7.867e-06 0.33

Etrasimod

W5VNF7_CANLF S1PR1 Sphingosine-1-phosphate receptor 1 4.573e-128 1.00
H9EUW9_MACMU S1PR1 Sphingosine 1-phosphate receptor 1 2.605e-107 1.00
S1PR1_RAT S1pr1 Sphingosine 1-phosphate receptor 1 3.049e-69 1.00
S1PR1_MOUSE S1pr1 Sphingosine 1-phosphate receptor 1 1.553e-60 1.00
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 7.145e-32 1.00
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.22e-16 1.00
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.107e-09 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9869 1.00
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.634e-101 0.41
FFAR1_RAT Ffar1 Free fatty acid receptor 1 2.445e-60 0.40
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 6.5e-48 0.41
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 9.424e-37 0.41
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 2.339e-36 0.41
UBA1_HUMAN UBA1 Ubiquitin-like modifier-activating enzyme 1 3.875e-36 0.29
SL9A1_HUMAN SLC9A1 Sodium/hydrogen exchanger 1 5.311e-23 0.33
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 2.247e-22 0.36
HST2_YEAST HST2 NAD-dependent protein deacetylase HST2 4.22e-20 0.32
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 6.661e-16 0.34
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.998e-15 0.35
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 7.327e-15 0.36
CP27A_HUMAN CYP27A1 Sterol 26-hydroxylase, mitochondrial 1.854e-14 0.32
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.037e-12 0.31
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 1.543e-12 0.28
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 5.251e-12 0.29
NR1H2_MOUSE Nr1h2 Oxysterols receptor LXR-beta 7.054e-11 0.32
AS3MT_HUMAN AS3MT Arsenite methyltransferase 2.194e-10 0.30
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 3.243e-09 0.78
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 8.646e-09 0.37
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 1.427e-08 0.30
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 8.788e-08 0.35
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 4.328e-07 0.31
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.031e-06 0.31
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 2.204e-06 0.36
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 5.97e-06 0.33
ANO1_HUMAN ANO1 Anoctamin-1 6.213e-06 0.29
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 8.27e-06 0.33

Gefapixant

P2RX2_HUMAN P2RX2 P2X purinoceptor 2 3.689e-125 1.00
P2RX3_RAT P2rx3 P2X purinoceptor 3 4.345e-113 1.00
P2RX3_HUMAN P2RX3 P2X purinoceptor 3 2.681e-34 1.00
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 2.283e-96 0.39
DYR_NEIGO folA Dihydrofolate reductase 5.432e-90 0.39
DYR1_ECOLX dhfrI Dihydrofolate reductase type 1 1.572e-76 0.39
DYR_LACLA folA Dihydrofolate reductase 5.544e-69 0.38
Q8Z9J9_SALTI folA Dihydrofolate reductase 9.129e-69 0.38
DRTS_PLABA Bifunctional dihydrofolate reductase-thymidylate synthase 2.777e-51 0.38
DYR_LACCA folA Dihydrofolate reductase 5.469e-45 0.39
DYR_CANAX DFR1 Dihydrofolate reductase 9.216e-39 0.36
O30463_MYCAV folA Dihydrofolate reductase 5.743e-37 0.38
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 3.327e-29 0.38
DYR_STAAW folA Dihydrofolate reductase 5.95e-29 0.30
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 1.699e-24 0.38
DYR_PNECA Dihydrofolate reductase 3.762e-24 0.38
Q81R22_BACAN dfrA Dihydrofolate reductase 6.613e-23 0.38
DYR_RAT Dhfr Dihydrofolate reductase 2.977e-20 0.36
DYR_HUMAN DHFR Dihydrofolate reductase 1.372e-17 0.38
DYR_STAAU folA Dihydrofolate reductase 1.392e-13 0.38
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 2.736e-11 0.39
Q9UUP5_PNEJI DHFR DHFR 4.735e-11 0.38
DYR_ECOLI folA Dihydrofolate reductase 2.539e-08 0.38

Filgotinib

Q5FVF5_RAT Jak1 Jak1 protein 2.9e-124 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.787e-14 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 7.916e-14 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 2.511e-13 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 5.407e-09 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 0.05918 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 0.1384 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 0.243 1.00
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.369e-178 0.36
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.143e-50 0.36
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.784e-46 0.36
O96526_LEIMA CRK3 Cdc2-related kinase 4.034e-37 0.40
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 8.233e-18 0.40
FAK1_HUMAN PTK2 Focal adhesion kinase 1 9.77e-15 0.64
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.127e-13 0.32
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 3.564e-13 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.322e-12 0.32
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 9.413e-12 0.29
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.611e-11 0.36
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 4.574e-11 0.33
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 5.731e-11 0.34
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.778e-10 0.34
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 8.971e-10 0.32
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.438e-09 0.28
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.567e-09 0.33
CDN1A_HUMAN CDKN1A Cyclin-dependent kinase inhibitor 1 7.778e-09 0.29
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 9.176e-09 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.015e-08 0.31
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.088e-08 0.32
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 2.539e-07 0.32
DRD2_MOUSE Drd2 D(2) dopamine receptor 2.99e-07 0.30
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 3.05e-07 0.28
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 3.727e-07 0.29
Q9BRH5_HUMAN DGAT1 DGAT1 protein 5.865e-07 0.30
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 7.834e-07 0.29
ALK_HUMAN ALK ALK tyrosine kinase receptor 8.164e-07 0.38
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.092e-06 0.28
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.481e-06 0.31
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 1.545e-06 0.30
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 1.703e-06 0.31
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.938e-06 0.37
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.432e-06 0.36
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 4.789e-06 0.32

Hydrocortisone_acetate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 8.667e-117 1.00
Q690N0_BOVIN PGR Progesterone receptor 1.337e-82 0.55
SHBG_HUMAN SHBG Sex hormone-binding globulin 5.382e-64 0.78
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.309e-57 0.52
CP19A_HUMAN CYP19A1 Aromatase 1.901e-48 0.44
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.393e-47 0.79
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.949e-42 0.78
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.586e-41 0.52
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.84e-39 0.40
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.311e-32 0.52
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.959e-29 0.54
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.581e-27 0.55
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.569e-24 0.43
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 3.39e-24 0.39
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 5.335e-24 0.40
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.357e-23 0.38
ANDR_RAT Ar Androgen receptor 1.736e-23 0.55
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 5.403e-20 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.09e-19 0.52
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 1.006e-17 0.28
GLNA_HUMAN GLUL Glutamine synthetase 1.11e-16 0.54
PRGR_RAT Pgr Progesterone receptor 8.882e-16 0.35
PRGR_RABIT PGR Progesterone receptor 1.554e-15 0.43
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.665e-15 0.40
GCR_RAT Nr3c1 Glucocorticoid receptor 1.11e-14 0.54
ANDR_MOUSE Ar Androgen receptor 1.564e-13 0.43
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.897e-13 0.52
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.214e-13 0.78
IL6_HUMAN IL6 Interleukin-6 3.694e-13 0.54
ERG2_YEAST ERG2 C-8 sterol isomerase 4.205e-11 0.43
ANDR_HUMAN AR Androgen receptor 1.228e-09 0.54
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.344e-08 0.67
MCR_RAT Nr3c2 Mineralocorticoid receptor 4.905e-08 0.50
TAT_HV112 tat Protein Tat 1.218e-06 0.29
CP19A_RAT Cyp19a1 Aromatase 4.018e-06 0.44

Ritlecitinib

JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 4.94e-99 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 1.807e-81 1.00
TEC_HUMAN TEC Tyrosine-protein kinase Tec 1.584e-12 1.00
TXK_HUMAN TXK Tyrosine-protein kinase TXK 3.385e-09 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 3.392e-06 1.00
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 5.715e-06 1.00
BTK_HUMAN BTK Tyrosine-protein kinase BTK 0.000546 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.625e-73 0.51
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.798e-49 0.38
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 3.774e-44 0.35
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 1.552e-35 0.42
CECR2_HUMAN CECR2 Cat eye syndrome critical region protein 2 2.234e-25 0.30
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 3.534e-23 0.32
TAF1_HUMAN TAF1 Transcription initiation factor TFIID subunit 1 2.636e-21 0.30
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.499e-18 0.32
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 3.186e-14 0.35
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 7.361e-14 0.34
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 2.724e-13 0.35
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 3.922e-13 0.29
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 6.598e-12 0.35
BRD9_HUMAN BRD9 Bromodomain-containing protein 9 9.943e-12 0.30
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 1.105e-10 0.29
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 1.476e-10 0.33
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.519e-10 0.35
DMPK_HUMAN DMPK Myotonin-protein kinase 2.781e-10 0.35
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 8.345e-10 0.35
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 2.208e-09 0.35
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 3.598e-09 0.29
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 5.266e-09 0.35
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 5.266e-09 0.35
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 7.01e-09 0.35
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 1.151e-08 0.35
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 7.486e-08 0.37
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 1.031e-07 0.29
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.031e-07 0.29
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.031e-07 0.29
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.031e-07 0.29
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 2.362e-07 0.29
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 2.8e-07 0.33
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 3.646e-07 0.51
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 4.144e-07 0.30
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 4.905e-07 0.29
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 4.905e-07 0.29
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 4.905e-07 0.29
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 4.914e-07 0.31
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 4.992e-07 0.35
EGFR_HUMAN EGFR Epidermal growth factor receptor 6.008e-07 0.39
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 7.531e-07 0.35
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 9.396e-07 0.29
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 1.242e-06 0.33
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 1.552e-06 0.33
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 2.181e-06 0.35
PB1_HUMAN PBRM1 Protein polybromo-1 2.222e-06 0.30
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 2.849e-06 0.29
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.849e-06 0.29
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 3.213e-06 0.30
SYT_YERPE thrS Threonine--tRNA ligase 3.213e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 4.596e-06 0.29
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 4.596e-06 0.29

Abrocitinib

JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 1.637e-93 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.043e-91 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 4.108e-77 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.234e-71 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.3005 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 0.9998 1.00
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 2.789e-51 0.41
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 7.687e-39 0.44
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 2.22e-16 0.41
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 9.714e-14 0.41
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 4.751e-13 0.28
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 2.079e-11 0.41
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 2.864e-11 0.41
DMPK_HUMAN DMPK Myotonin-protein kinase 4.012e-11 0.41
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 4.199e-11 0.41
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 1.289e-10 0.28
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.324e-10 0.41
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 3.81e-10 0.41
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 9.792e-10 0.41
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 9.792e-10 0.41
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.289e-09 0.41
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 4.099e-09 0.28
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 4.42e-08 0.41
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 1.149e-07 0.28
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.149e-07 0.28
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.149e-07 0.28
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.149e-07 0.28
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 2.617e-07 0.28
GRK5_HUMAN GRK5 G protein-coupled receptor kinase 5 4.281e-07 0.31
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 5.408e-07 0.28
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 5.408e-07 0.28
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 5.408e-07 0.28
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1.032e-06 0.28
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 2.109e-06 0.41
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 2.109e-06 0.41
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 3.059e-06 0.34
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 3.105e-06 0.28
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.105e-06 0.28
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 4.993e-06 0.28
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 4.993e-06 0.28
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 5.415e-06 0.29
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 6.65e-06 0.41
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 8.354e-06 0.41

Umbralisib

PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5.107e-79 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 8.184e-112 0.44
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 1.53e-78 0.43
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.9e-76 0.44
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 1.169e-70 0.44
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 6.223e-66 0.41
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1.104e-56 0.44
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 6.918e-48 0.44
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 9.292e-46 0.42
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 4.828e-39 0.44
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.818e-35 0.44
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1.839e-28 0.44
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 4.074e-25 0.44
CDPK4_PLAF7 CPK4 Calcium-dependent protein kinase 4 3.68e-20 0.32
EGFR_HUMAN EGFR Epidermal growth factor receptor 3.997e-15 0.44
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.277e-12 0.37
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 3.802e-11 0.33
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.489e-10 0.37
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.727e-10 0.43
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.818e-10 0.34
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 9.217e-10 0.30
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 3.402e-09 0.36
AVR2A_HUMAN ACVR2A Activin receptor type-2A 7.149e-09 0.30
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 7.149e-09 0.30
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 8.292e-09 0.39
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 5.975e-08 0.30
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 5.975e-08 0.30
MYO3A_HUMAN MYO3A Myosin-IIIa 5.975e-08 0.30
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 9.394e-08 0.30
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.408e-07 0.30
MYO3B_HUMAN MYO3B Myosin-IIIb 1.408e-07 0.30
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 1.408e-07 0.30
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.55e-07 0.32
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 2.996e-07 0.30
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 2.996e-07 0.30
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 2.996e-07 0.30
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 5.865e-07 0.30
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 8.732e-07 0.30
AVR2B_HUMAN ACVR2B Activin receptor type-2B 1.845e-06 0.30
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.845e-06 0.30
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 3.025e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 3.025e-06 0.30
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.025e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 4.749e-06 0.30
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 5.04e-06 0.31
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 7.185e-06 0.30
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 7.185e-06 0.30
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 7.185e-06 0.30

Hydrocortisone_succinate

GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.814e-48 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.578e-105 0.79
Q690N0_BOVIN PGR Progesterone receptor 7.105e-60 0.49
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.487e-55 0.71
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.314e-53 0.49
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.564e-39 0.49
GCR_HUMAN NR3C1 Glucocorticoid receptor 3.947e-39 0.71
CP19A_HUMAN CYP19A1 Aromatase 2.692e-34 0.40
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 9.449e-30 0.49
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.028e-26 0.50
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.073e-25 0.49
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.418e-22 0.36
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.753e-22 0.36
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.212e-22 0.41
ANDR_RAT Ar Androgen receptor 1.197e-19 0.49
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 2.499e-19 0.29
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.455e-18 0.36
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.402e-17 0.49
GCR_RAT Nr3c1 Glucocorticoid receptor 4.441e-16 0.50
GLNA_HUMAN GLUL Glutamine synthetase 1.887e-15 0.50
PRGR_RAT Pgr Progesterone receptor 8.216e-15 0.32
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.743e-14 0.36
PRGR_RABIT PGR Progesterone receptor 2.331e-14 0.38
ANDR_MOUSE Ar Androgen receptor 2.136e-12 0.41
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.637e-12 0.49
IL6_HUMAN IL6 Interleukin-6 2.682e-12 0.50
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.276e-12 0.36
MCR_HUMAN NR3C2 Mineralocorticoid receptor 6.069e-11 0.71
ERG2_YEAST ERG2 C-8 sterol isomerase 3.896e-10 0.40
ANDR_HUMAN AR Androgen receptor 2.493e-08 0.50
PPO2_AGABI PPO2 Polyphenol oxidase 2 7.934e-08 0.59
MCR_RAT Nr3c2 Mineralocorticoid receptor 1.512e-07 0.47
PRGR_HUMAN PGR Progesterone receptor 2.99e-07 0.50

Betamethasone_phosphate

GCR_HUMAN NR3C1 Glucocorticoid receptor 3.637e-45 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 0.3831 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.5947 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
ATTY_RAT Tat Tyrosine aminotransferase 2.712e-152 0.57
GCR_RAT Nr3c1 Glucocorticoid receptor 8.149e-94 0.77
Q690N0_BOVIN PGR Progesterone receptor 2.059e-54 0.77
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.441e-16 0.39
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.743e-14 0.50
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 8.319e-11 0.34
GLNA_HUMAN GLUL Glutamine synthetase 8.319e-11 0.34
IL6_HUMAN IL6 Interleukin-6 1.221e-08 0.34
MMP1_HUMAN MMP1 Interstitial collagenase 3.97e-08 0.59

Dabigatran

THRB_HUMAN F2 Prothrombin 6.057e-44 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
FA10_HUMAN F10 Coagulation factor X 6.015e-13 1.00
HEPS_HUMAN HPN Serine protease hepsin 7.806e-07 1.00
PLMN_HUMAN PLG Plasminogen 3.267e-06 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 4.608e-58 0.40
Q28731_RABIT thrombin Thrombin 2.505e-39 0.64
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 6.511e-39 0.32
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 6.185e-32 0.32
Q1L4E8_MACMU Mas-related G protein-coupled receptor X1 1.3e-30 0.31
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 8.075e-29 0.30
E2QDN0_ECOLX thyA Thymidylate synthase 4.409e-21 0.29
DYR_ENTFC folA Dihydrofolate reductase 2.035e-19 0.31
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 2.004e-18 0.29
A8K2H7_HUMAN C3AR1 Complement component 3a receptor 1, isoform CRA_a 1.11e-16 0.32
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 1.454e-14 0.36
INSR_HUMAN INSR Insulin receptor 3.486e-14 0.37
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 7.139e-14 0.34
MRGX2_HUMAN MRGPRX2 Mas-related G-protein coupled receptor member X2 8.229e-13 0.31
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.173e-12 0.36
FA7_HUMAN F7 Coagulation factor VII 4.039e-12 0.33
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 5.511e-12 0.29
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 2.006e-11 0.31
FIBB_HUMAN FGB Fibrinogen beta chain 5.659e-11 0.29
ITB3_HUMAN ITGB3 Integrin beta-3 4.502e-10 0.34
GIP_HUMAN GIP Gastric inhibitory polypeptide 4.612e-10 0.29
TRY1_HUMAN PRSS1 Trypsin-1 5.814e-10 0.35
KLK1_HUMAN KLK1 Kallikrein-1 2.188e-09 0.35
RASH_HUMAN HRAS GTPase HRas 2.519e-08 0.32
DYR_MOUSE Dhfr Dihydrofolate reductase 2.574e-08 0.31
FA9_HUMAN F9 Coagulation factor IX 2.605e-08 0.31
1433G_HUMAN YWHAG 14-3-3 protein gamma 4.387e-08 0.28
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 9.47e-08 0.30
TRYP_PIG Trypsin 2.056e-07 0.35
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.12e-07 0.35
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 2.845e-07 0.31
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 2.909e-07 0.34
UROK_HUMAN PLAU Urokinase-type plasminogen activator 5.567e-07 0.35

Aprocitentan

EDNRB_HUMAN EDNRB Endothelin receptor type B 1.166e-41 1.00
EDNRA_HUMAN EDNRA Endothelin-1 receptor 3.044e-26 1.00
EDNRA_PIG EDNRA Endothelin-1 receptor 1.631e-70 0.73
EDNRA_RAT Ednra Endothelin-1 receptor 4.737e-07 0.62

Futibatinib

FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 8.018e-41 1.00
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 3.087e-07 1.00
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 3.447e-05 1.00
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 0.000214 1.00
PXL2A_HUMAN PRXL2A Peroxiredoxin-like 2A 2.342e-63 0.51
BTK_HUMAN BTK Tyrosine-protein kinase BTK 4.631e-57 0.56
HCK_HUMAN HCK Tyrosine-protein kinase HCK 5.32e-43 0.51
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.604e-35 0.60
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 4.018e-31 0.51
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 4.481e-28 0.41
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.468e-26 0.62
TEC_HUMAN TEC Tyrosine-protein kinase Tec 2.642e-24 0.51
NR2C2_HUMAN NR2C2 Nuclear receptor subfamily 2 group C member 2 1.046e-23 0.29
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 1.458e-23 0.36
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.9e-22 0.51
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 3.769e-21 0.37
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 6.856e-21 0.37
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 1.758e-19 0.39
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.981e-19 0.39
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.231e-18 0.51
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 8.086e-18 0.39
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1.11e-16 0.39
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 9.992e-16 0.39
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 3.73e-14 0.51
CSK_HUMAN CSK Tyrosine-protein kinase CSK 6.658e-12 0.51
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 1.316e-11 0.38
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.565e-11 0.51
TIE2_HUMAN TEK Angiopoietin-1 receptor 5.452e-11 0.35
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 2.367e-08 0.31
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.893e-08 0.51
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 5.245e-08 0.31
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 9.69e-08 0.51
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.011e-07 0.51
FER_HUMAN FER Tyrosine-protein kinase Fer 1.15e-07 0.51
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.884e-07 0.51
BLK_HUMAN BLK Tyrosine-protein kinase Blk 2.169e-07 0.51
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.208e-07 0.51
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 3.028e-07 0.34
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 3.312e-07 0.51
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 5.883e-07 0.51
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 2.454e-06 0.51

Avutometinib

MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 1.584e-37 1.00
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 8.703e-22 1.00
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.668e-42 0.42
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 5.626e-37 0.42
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 1.22e-31 0.36
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 1.693e-22 0.35
TRPM7_MOUSE Trpm7 Transient receptor potential cation channel subfamily M member 7 1.253e-20 0.33
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 2.048e-19 0.30
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 2.516e-19 0.36
AL1A3_HUMAN ALDH1A3 Aldehyde dehydrogenase family 1 member A3 7.772e-16 0.43
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 7.261e-14 0.42
STS_HUMAN STS Steryl-sulfatase 1.561e-11 0.38
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 4.636e-07 0.35
CHLE_HORSE BCHE Cholinesterase 1.622e-06 0.35
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 8.96e-06 0.32

Tepotinib

MET_HUMAN MET Hepatocyte growth factor receptor 1.27e-22 1.00
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 6.174e-23 0.32
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.713e-20 0.32
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 3.762e-20 0.43
FNTA_MOUSE Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.256e-19 0.32
FNTB_MOUSE Fntb Protein farnesyltransferase subunit beta 1.256e-19 0.32
CDPK4_PLAF7 CPK4 Calcium-dependent protein kinase 4 9.507e-18 0.28
GYRB_MYCTU gyrB DNA gyrase subunit B 4.039e-17 0.30
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.11e-16 0.33
GYRA_MYCTU gyrA DNA gyrase subunit A 5.551e-16 0.30
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 8.882e-16 0.35
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 2.283e-13 0.32
HRH3_RAT Hrh3 Histamine H3 receptor 1.834e-10 0.43
DUT_HUMAN DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 3.969e-10 0.32
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 9.912e-10 0.32
PGTB1_HUMAN PGGT1B Geranylgeranyl transferase type-1 subunit beta 1.201e-09 0.30
ACES_RAT Ache Acetylcholinesterase 3.281e-09 0.50
MTLR_HUMAN MLNR Motilin receptor 3.348e-09 0.40
PGTB1_BOVIN PGGT1B Geranylgeranyl transferase type-1 subunit beta 1.277e-08 0.32
FABI_STAA8 fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI 1.291e-08 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 3.771e-08 0.33
FNTB_BOVIN FNTB Protein farnesyltransferase subunit beta 3.924e-08 0.32
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 4.042e-08 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 4.59e-08 0.43
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 7.169e-08 0.39
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 7.605e-08 0.34
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 1.881e-07 0.35
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 4.055e-07 0.32
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 5.815e-07 0.28
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 2.783e-06 0.32
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 4.925e-06 0.30
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 6.368e-06 0.37
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 7.739e-06 0.30
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 7.876e-06 0.37

Hydroxystilbamidine

TRYP_PIG Trypsin 2.22e-16 1.00
MAZF_ECOLI mazF Endoribonuclease toxin MazF 5.523e-13 1.00
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 0.0001741 1.00
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 0.001097 1.00
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 0.002538 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 0.005635 1.00
STRP_STRP1 ska Streptokinase A 0.7392 1.00
KLK_PIG Glandular kallikrein 4.017e-127 0.38
ACRO_PIG ACR Acrosin 7.765e-96 0.37
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 3.379e-50 0.41
TRY1_BOVIN Cationic trypsin 1.152e-45 0.44
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 1.588e-42 0.37
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 5.166e-42 0.33
UROK_HUMAN PLAU Urokinase-type plasminogen activator 4.487e-40 0.51
THRB_BOVIN F2 Prothrombin 1.449e-32 0.44
TRY1_HUMAN PRSS1 Trypsin-1 7.411e-27 0.44
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.963e-26 0.38
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.341e-22 0.48
PLMN_HUMAN PLG Plasminogen 1.912e-22 0.51
FA10_HUMAN F10 Coagulation factor X 3.07e-22 0.44
FA10_BOVIN F10 Coagulation factor X 1.914e-17 0.37
THRB_HUMAN F2 Prothrombin 3.36e-17 0.39
S100B_RAT S100b Protein S100-B 8.882e-16 0.30
KLK1_HUMAN KLK1 Kallikrein-1 1.221e-15 0.51
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.221e-15 0.33
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 2.656e-13 0.33
TYRO_MOUSE Tyr Tyrosinase 3.235e-13 0.32
TTHY_HUMAN TTR Transthyretin 6.206e-13 0.33
HEPS_HUMAN HPN Serine protease hepsin 3.562e-12 0.37
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 6.671e-12 0.43
S100B_HUMAN S100B Protein S100-B 2.335e-11 0.33
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 5.727e-11 0.34
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.441e-10 0.33
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 3.648e-09 0.31
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 3.648e-09 0.31
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 7.049e-09 0.30
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 9.562e-09 0.43
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.584e-08 0.33
A4_HUMAN APP Amyloid-beta precursor protein 3.597e-08 0.36
BXA1_CLOBH botA Botulinum neurotoxin type A 6.592e-08 0.36
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.29e-07 0.37
CBPB1_PIG CPB1 Carboxypeptidase B 2.996e-07 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.409e-07 0.33
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 5.865e-07 0.30
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.681e-06 0.29
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 5.632e-06 0.40
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 7.334e-06 0.33

Tedizolid

AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 5.94e-14 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 0.2045 1.00
HMCS1_RAT Hmgcs1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1.509e-47 0.30
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 1.352e-41 0.36
3BHS2_HUMAN HSD3B2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 4.474e-39 0.31
KITH_VZVD TK Thymidine kinase 5.817e-28 0.29
DNK_DROME dnk Deoxynucleoside kinase 4.126e-25 0.30
HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.516e-22 0.33
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 3.545e-21 0.33
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 1.627e-19 0.30
FA10_RABIT F10 Coagulation factor X 6.345e-19 0.35
SCD5_HUMAN SCD5 Stearoyl-CoA desaturase 5 9.507e-18 0.28
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 9.59e-18 0.34
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 1.803e-17 0.38
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 4.441e-16 0.31
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 2.998e-15 0.30
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.479e-13 0.33
KNG1_HUMAN KNG1 Kininogen-1 3.786e-13 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 3.466e-12 0.42
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 9.019e-11 0.31
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 5.74e-07 0.28
KTHY_MYCTU tmk Thymidylate kinase 8.656e-07 0.30

Ivosidenib

IDHC_HUMAN IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 2.518e-12 1.00
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.577e-14 0.33

Ripretinib

PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 8.785e-10 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.552e-09 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.639e-09 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 0.03895 1.00
RASK_HUMAN KRAS GTPase KRas 1.678e-60 0.61
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 3.861e-29 0.29
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 2.374e-28 0.31
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 2.049e-21 0.38
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 7.382e-21 0.31
EPHB_MYCTO Epoxide hydrolase B 3.488e-18 0.29
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 4.43e-14 0.30
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 8.271e-14 0.37
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 8.982e-14 0.33
CDKL1_HUMAN CDKL1 Cyclin-dependent kinase-like 1 2.482e-13 0.29
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.277e-12 0.31
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.284e-12 0.31
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 6.464e-12 0.29
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 9.033e-12 0.33
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 8.006e-11 0.31
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 8.553e-11 0.39
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 3.315e-10 0.31
FER_HUMAN FER Tyrosine-protein kinase Fer 3.612e-10 0.30
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 5.388e-10 0.29
PE2R3_RAT Ptger3 Prostaglandin E2 receptor EP3 subtype 5.866e-10 0.29
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 8.708e-10 0.30
KC1G3_HUMAN CSNK1G3 Casein kinase I isoform gamma-3 9.314e-10 0.31
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 2.635e-09 0.29
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.649e-09 0.33
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 3.636e-09 0.32
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 4.407e-09 0.30
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 5.022e-09 0.61
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 5.105e-09 0.32
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 6.159e-09 0.29
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 6.31e-09 0.37
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 7.188e-09 0.31
FRK_HUMAN FRK Tyrosine-protein kinase FRK 9.246e-09 0.31
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 9.882e-09 0.29
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 9.882e-09 0.29
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 1.322e-08 0.29
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 1.723e-08 0.31
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 3.032e-08 0.29
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 3.711e-08 0.31
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 4.144e-08 0.30
MK13_HUMAN MAPK13 Mitogen-activated protein kinase 13 4.453e-08 0.31
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 7.008e-08 0.31
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 7.964e-08 0.29
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 7.964e-08 0.29
MYO3A_HUMAN MYO3A Myosin-IIIa 7.964e-08 0.29
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 7.964e-08 0.29
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 9.361e-08 0.33
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 1.215e-07 0.33
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.277e-07 0.31
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.849e-07 0.29
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.849e-07 0.29
MYO3B_HUMAN MYO3B Myosin-IIIb 1.849e-07 0.29
MINK1_HUMAN MINK1 Misshapen-like kinase 1 2.352e-07 0.31
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 2.534e-07 0.30
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.706e-07 0.61
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 3.683e-07 0.29
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 3.727e-07 0.29
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 3.884e-07 0.29
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 3.917e-07 0.30
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 4.765e-07 0.31
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 5.757e-07 0.32
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 7.731e-07 0.31
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.002e-06 0.33
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 1.046e-06 0.30
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.142e-06 0.28
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 1.314e-06 0.31
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.359e-06 0.29
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.359e-06 0.29
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 1.359e-06 0.29
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 1.359e-06 0.29
AVR2B_HUMAN ACVR2B Activin receptor type-2B 2.32e-06 0.29
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 2.32e-06 0.29
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 2.32e-06 0.29
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 2.86e-06 0.29
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 3.077e-06 0.32
AURKB_HUMAN AURKB Aurora kinase B 3.121e-06 0.34
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 3.661e-06 0.31
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.726e-06 0.31
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 3.77e-06 0.29
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.77e-06 0.29
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 4.237e-06 0.31
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 4.286e-06 0.30
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 5.193e-06 0.33
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 5.232e-06 0.30
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 5.875e-06 0.29
INSRR_HUMAN INSRR Insulin receptor-related protein 5.875e-06 0.29
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 6.773e-06 0.35
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 7.061e-06 0.31
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 7.779e-06 0.31
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 7.854e-06 0.30
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 8.656e-06 0.30
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 8.827e-06 0.29
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 8.827e-06 0.29
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 8.827e-06 0.29
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 8.827e-06 0.29

Oliceridine

OPRM_HUMAN OPRM1 Mu-type opioid receptor 5.17e-09 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.0008866 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.7799 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.9291 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9832 1.00
ICMT_HUMAN ICMT Protein-S-isoprenylcysteine O-methyltransferase 3.207e-35 0.34
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 1.654e-14 0.30

Upadacitinib

JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 3.323e-08 1.00
HGFL_HUMAN MST1 Hepatocyte growth factor-like protein 3.028e-18 0.29
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.302e-12 0.35
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 2.381e-12 0.32
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.376e-08 0.40
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 7.766e-08 0.40

Ensartinib

ALK_HUMAN ALK ALK tyrosine kinase receptor 5.694e-08 1.00
TIE2_MOUSE Tek Angiopoietin-1 receptor 3.527e-52 0.42
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 1.666e-42 0.42
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.879e-36 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 1.132e-31 0.77
BACE2_MOUSE Bace2 Beta-secretase 2 1.637e-24 0.29
RON_MOUSE Mst1r Macrophage-stimulating protein receptor 9.797e-19 0.42
Q9GSG8_AEDAE Ultraspiracle isoform-A 2.22e-16 0.31
RON_HUMAN MST1R Macrophage-stimulating protein receptor 4.219e-14 0.43
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 5.504e-13 0.42
BACE1_MOUSE Bace1 Beta-secretase 1 8.894e-12 0.29
CCR2_RAT Ccr2 C-C chemokine receptor type 2 1.482e-11 0.28
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.795e-11 0.42
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 7.11e-11 0.42
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 2.361e-10 0.42
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 2.361e-10 0.42
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 6.796e-10 0.42
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 6.796e-10 0.42
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 6.796e-10 0.42
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 7.389e-10 0.29
TAAR1_RAT Taar1 Trace amine-associated receptor 1 9.84e-10 0.30
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.74e-09 0.42
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1.74e-09 0.42
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 1.74e-09 0.42
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 4.043e-09 0.42
BACE2_HUMAN BACE2 Beta-secretase 2 8.492e-09 0.31
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 8.65e-09 0.42
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.222e-08 0.29
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 1.464e-08 0.30
BACE1_HUMAN BACE1 Beta-secretase 1 1.476e-08 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.726e-08 0.42
INSRR_HUMAN INSRR Insulin receptor-related protein 3.242e-08 0.42
MTLR_HUMAN MLNR Motilin receptor 4.499e-08 0.31
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 5.782e-08 0.42
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 5.782e-08 0.42
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.854e-08 0.42
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 1.613e-07 0.42
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 1.613e-07 0.42
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 1.613e-07 0.42
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 2.55e-07 0.42
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 2.55e-07 0.42
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 3.906e-07 0.42
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 3.906e-07 0.42
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 3.906e-07 0.42
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 4.136e-07 0.30
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.481e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.481e-07 0.29
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 5.673e-07 0.42
DMPK_HUMAN DMPK Myotonin-protein kinase 5.818e-07 0.42
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 5.818e-07 0.42
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 8.316e-07 0.29
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 8.449e-07 0.42
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.2e-06 0.42
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 1.2e-06 0.42
ACRO_HUMAN ACR Acrosin 1.439e-06 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.669e-06 0.42
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1.669e-06 0.42
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 1.669e-06 0.42
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.669e-06 0.42
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 1.669e-06 0.42
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.959e-06 0.29
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 2.278e-06 0.42
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.278e-06 0.42
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 4.041e-06 0.42
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 4.041e-06 0.42
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 4.041e-06 0.42
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 6.769e-06 0.42
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 6.769e-06 0.42
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 6.769e-06 0.42
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 8.213e-06 0.42
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 8.599e-06 0.42
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 8.599e-06 0.42

Mometasone_furoate

PRGR_HUMAN PGR Progesterone receptor 0.0006495 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.3286 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.4004 1.00
ATTY_RAT Tat Tyrosine aminotransferase 4.567e-135 0.50
GCR_RAT Nr3c1 Glucocorticoid receptor 5.799e-67 0.60
Q690N0_BOVIN PGR Progesterone receptor 7.163e-43 0.60
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.51e-34 0.60
GCR_MOUSE Nr3c1 Glucocorticoid receptor 5.252e-12 0.39
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.37e-09 0.30
GLNA_HUMAN GLUL Glutamine synthetase 1.37e-09 0.30
IL6_HUMAN IL6 Interleukin-6 1.106e-07 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 4.073e-07 0.51
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 3.082e-06 0.28

Estramustine_phosphate

PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 0.004607 1.00
STS_HUMAN STS Steryl-sulfatase 9.934e-136 0.52
Q95MF8_PIG Sulfotransferase 2.018e-63 0.36
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 9.938e-57 0.41
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.962e-56 0.48
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 2.78e-51 0.36
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.478e-35 0.39
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 2.597e-33 0.43
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 2.99e-29 0.38
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.237e-26 0.43
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 1.611e-26 0.43
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.07e-23 0.38
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 7.345e-19 0.43
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.606e-17 0.53
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.119e-17 0.43
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 3.331e-17 0.43
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.11e-16 0.43
ESR1_MOUSE Esr1 Estrogen receptor 2.311e-13 0.43
ESR2_MOUSE Esr2 Estrogen receptor beta 2.311e-13 0.43
ESR1_HUMAN ESR1 Estrogen receptor 5.126e-13 0.44
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 3.637e-12 0.31
ESR1_RAT Esr1 Estrogen receptor 1.081e-10 0.59
Q690N0_BOVIN PGR Progesterone receptor 7.363e-10 0.43
ESR2_HUMAN ESR2 Estrogen receptor beta 1.522e-09 0.44
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.879e-09 0.43
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.841e-07 0.30
CP19A_HUMAN CYP19A1 Aromatase 3.61e-07 0.39
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.583e-06 0.48
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.06e-06 0.43
ANDR_RAT Ar Androgen receptor 4.056e-06 0.43

Avapritinib

PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 0.04408 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 0.3381 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 0.3884 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.488e-10 0.36
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.987e-06 0.38
SMO_MOUSE Smo Smoothened homolog 3.186e-06 0.31

Tovorafenib

BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 0.9826 1.00
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.379e-06 0.28

Avexitide

NTR2_HUMAN NTSR2 Neurotensin receptor type 2 2.516e-217 0.47
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 7.568e-181 0.51
MC5R_MOUSE Mc5r Melanocortin receptor 5 4.013e-156 0.42
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 5.784e-150 0.45
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 9.716e-148 0.52
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.089e-144 0.51
CD36_RAT Cd36 Platelet glycoprotein 4 1.696e-142 0.42
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 1.743e-123 0.43
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 2.181e-123 0.42
MC4R_MOUSE Mc4r Melanocortin receptor 4 1.109e-113 0.42
NTR1_RAT Ntsr1 Neurotensin receptor type 1 5.416e-113 0.45
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 6.311e-112 0.43
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 6.976e-110 0.45
FURIN_HUMAN FURIN Furin 2.638e-108 0.36
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 7.728e-106 0.41
EDNRB_RAT Ednrb Endothelin receptor type B 7.237e-104 0.49
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.736e-102 0.47
MC3R_MOUSE Mc3r Melanocortin receptor 3 5.255e-101 0.42
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 1.402e-100 0.42
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.499e-99 0.41
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 8.971e-91 0.39
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 1.804e-89 0.35
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 2.003e-86 0.36
OPRM_RAT Oprm1 Mu-type opioid receptor 3.033e-86 0.47
RENI_RAT Ren1 Renin 4.577e-86 0.38
KISSR_HUMAN KISS1R KiSS-1 receptor 3.087e-84 0.45
CBX7_HUMAN CBX7 Chromobox protein homolog 7 4.122e-84 0.36
SORT_HUMAN SORT1 Sortilin 5.803e-84 0.45
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 5.81e-83 0.33
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1.369e-81 0.39
NK2R_MESAU TACR2 Substance-K receptor 6.051e-79 0.45
MC3R_HUMAN MC3R Melanocortin receptor 3 4.461e-76 0.41
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.393e-73 0.45
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 2.277e-72 0.36
O57585_DANRE oprd1a Opioid receptor homologue 2.277e-72 0.36
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.717e-70 0.47
OPRD_RAT Oprd1 Delta-type opioid receptor 7.301e-69 0.44
BXA1_CLOBH botA Botulinum neurotoxin type A 1.63e-68 0.40
GRPR_RAT Grpr Gastrin-releasing peptide receptor 8.855e-68 0.47
SURA_ECOLI surA Chaperone SurA 2.657e-66 0.53
OPRM_CAVPO OPRM1 Mu-type opioid receptor 9.408e-66 0.47
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.678e-65 0.36
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 5.516e-64 0.52
NK2R_RAT Tacr2 Substance-K receptor 5.388e-63 0.47
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 5.239e-62 0.41
NK1R_CAVPO TACR1 Substance-P receptor 3.877e-59 0.47
MC4R_HUMAN MC4R Melanocortin receptor 4 4.391e-59 0.41
Q8I6Z5_PLAF7 Plasmepsin V 1.088e-58 0.35
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 7.023e-57 0.37
RENI1_MOUSE Ren1 Renin-1 1.401e-53 0.33
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 2.429e-53 0.40
PRO_HTL1A gag-pro Gag-Pro polyprotein 7.99e-52 0.40
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 8.317e-52 0.46
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 2.261e-50 0.33
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 1.007e-49 0.36
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 1.02e-49 0.31
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.517e-47 0.35
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 1.974e-47 0.38
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 6.761e-46 0.31
OPRX_MOUSE Oprl1 Nociceptin receptor 2.272e-44 0.34
EDNRA_PIG EDNRA Endothelin-1 receptor 1.563e-43 0.40
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 2.543e-43 0.35
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 2.543e-43 0.35
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.724e-43 0.36
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 2.641e-42 0.31
CBX8_HUMAN CBX8 Chromobox protein homolog 8 3.24e-42 0.31
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 9.759e-42 0.39
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 2.649e-40 0.37
NK3R_CAVPO TACR3 Neuromedin-K receptor 4.878e-40 0.39
NMBR_RAT Nmbr Neuromedin-B receptor 9.208e-39 0.48
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 3.638e-38 0.40
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 6.923e-38 0.40
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 9.255e-38 0.35
NK1R_RAT Tacr1 Substance-P receptor 2.837e-37 0.46
Q5D7U5_CHICK OXTR Oxytocin-like receptor 3.913e-37 0.29
A4HSF7_LEIIN TRYR Trypanothione reductase 4.621e-37 0.46
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.994e-37 0.46
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 3.066e-36 0.36
CBX5_HUMAN CBX5 Chromobox protein homolog 5 1.097e-35 0.28
MMP11_MOUSE Mmp11 Stromelysin-3 8.167e-35 0.30
FSHR_RAT Fshr Follicle-stimulating hormone receptor 2.093e-34 0.43
NK3R_RAT Tacr3 Neuromedin-K receptor 1.307e-33 0.47
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.147e-33 0.49
KLK3_HUMAN KLK3 Prostate-specific antigen 3.996e-33 0.32
NRP1_RAT Nrp1 Neuropilin-1 1.532e-31 0.52
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 3.057e-30 0.37
CATE_HUMAN CTSE Cathepsin E 1.793e-29 0.37
HEPS_HUMAN HPN Serine protease hepsin 4.278e-28 0.37
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 8.494e-28 0.46
PAPA1_CARPA Papain 4.422e-27 0.44
ANPRC_HUMAN NPR3 Atrial natriuretic peptide receptor 3 1.034e-26 0.36
A3EZI9_9HEPC NS3 Genome polyprotein 1.116e-25 0.36
RENI_HUMAN REN Renin 2.124e-25 0.44
TR10A_HUMAN TNFRSF10A Tumor necrosis factor receptor superfamily member 10A 6.98e-25 0.31
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 8.943e-25 0.30
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 2.398e-23 0.29
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 3.308e-23 0.28
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 3.62e-23 0.39
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.974e-23 0.41
PEPA_PIG PGA Pepsin A 5.897e-23 0.40
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 9.165e-23 0.34
AMPN_HUMAN ANPEP Aminopeptidase N 1.705e-22 0.40
NK3R_HUMAN TACR3 Neuromedin-K receptor 2.171e-22 0.41
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 3.565e-22 0.41
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 5.108e-22 0.51
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 5.386e-22 0.35
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 7.982e-22 0.35
CASPA_HUMAN CASP10 Caspase-10 9.904e-22 0.38
CFAB_HUMAN CFB Complement factor B 1.293e-21 0.34
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 4.76e-21 0.42
OPRM_MOUSE Oprm1 Mu-type opioid receptor 7.498e-20 0.42
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 8.357e-20 0.32
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 1.249e-19 0.51
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 2.013e-19 0.31
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 2.018e-19 0.34
VM1B1_BOTAS Snake venom metalloproteinase BaP1 2.322e-19 0.31
IDE_HUMAN IDE Insulin-degrading enzyme 4.764e-19 0.37
Q9ERC0_RAT Npy2r Neuropeptide Y receptor Y2 6.158e-19 0.30
ST14_MOUSE St14 Suppressor of tumorigenicity 14 protein homolog 8.69e-19 0.28
OPRD_HUMAN OPRD1 Delta-type opioid receptor 9.963e-19 0.53
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.504e-18 0.34
PEPC_HUMAN PGC Gastricsin 2.251e-18 0.29
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 2.781e-18 0.44
POLG_WNV Genome polyprotein 3.326e-18 0.31
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 5.53e-18 0.28
GRIA1_RAT Gria1 Glutamate receptor 1 7.466e-18 0.32
OXYR_MOUSE Oxtr Oxytocin receptor 1.045e-17 0.28
ELAS_PSEAE lasB Elastase 1.416e-17 0.31
TRY1_BOVIN Cationic trypsin 1.99e-17 0.34
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 4.394e-17 0.36
O07911_STAAU agrC AgrC 4.541e-17 0.34
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.11e-16 0.53
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.22e-16 0.40
OPRK_RAT Oprk1 Kappa-type opioid receptor 4.441e-16 0.42
Q72874_9HIV1 pol Pol polyprotein 5.551e-16 0.45
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 9.992e-16 0.48
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.998e-15 0.46
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 2.109e-15 0.32
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 2.22e-15 0.34
CCNA2_HUMAN CCNA2 Cyclin-A2 2.442e-15 0.45
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 2.887e-15 0.29
CATD_HUMAN CTSD Cathepsin D 3.109e-15 0.37
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 3.442e-15 0.36
MMP11_HUMAN MMP11 Stromelysin-3 7.438e-15 0.28
CATD_BOVIN CTSD Cathepsin D 1.665e-14 0.34
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 3.997e-14 0.31
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 6.517e-14 0.38
Q95PM0_TRYBR rhodesain Cysteine protease 2.047e-13 0.33
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 2.389e-13 0.41
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 2.395e-13 0.41
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 7.051e-13 0.36
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.041e-12 0.30
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.215e-12 0.30
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.816e-12 0.51
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 3.059e-12 0.45
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 3.497e-12 0.30
ECE1_RAT Ece1 Endothelin-converting enzyme 1 3.938e-12 0.34
THRB_HUMAN F2 Prothrombin 4.25e-12 0.37
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 8.168e-12 0.36
AGRA_STAAU agrA Accessory gene regulator protein A 8.344e-12 0.29
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.321e-11 0.41
V2R_PIG AVPR2 Vasopressin V2 receptor 1.402e-11 0.29
CASP4_HUMAN CASP4 Caspase-4 6.408e-11 0.38
CMA1_HUMAN CMA1 Chymase 7.377e-11 0.37
CTRC_HUMAN CTRC Chymotrypsin-C 8.348e-11 0.37
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 9.356e-11 0.31
GRAB_HUMAN GZMB Granzyme B 9.661e-11 0.29
CTRA_BOVIN Chymotrypsinogen A 1.083e-10 0.32
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.757e-10 0.44
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.912e-10 0.45
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.912e-10 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.302e-10 0.34
NMBR_HUMAN NMBR Neuromedin-B receptor 2.499e-10 0.46
PRSS8_HUMAN PRSS8 Prostasin 3.752e-10 0.29
PRTN3_HUMAN PRTN3 Myeloblastin 3.829e-10 0.31
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 5.123e-10 0.34
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 5.722e-10 0.31
CASP9_HUMAN CASP9 Caspase-9 6.311e-10 0.38
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 6.967e-10 0.39
OPRX_HUMAN OPRL1 Nociceptin receptor 4.732e-09 0.40
ANPRA_HUMAN NPR1 Atrial natriuretic peptide receptor 1 4.926e-09 0.30
ACE_HUMAN ACE Angiotensin-converting enzyme 6.215e-09 0.48
PAR1_HUMAN F2R Proteinase-activated receptor 1 6.549e-09 0.38
CATB_HUMAN CTSB Cathepsin B 1.031e-08 0.46
NK2R_RABIT TACR2 Substance-K receptor 1.27e-08 0.45
Q4U254_9ENTO protease Protease 1.546e-08 0.42
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 2.671e-08 0.45
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.724e-08 0.41
D2K2A8_9HEPC NS4A Non-structural protein 4A 3.026e-08 0.36
AMPL_HUMAN LAP3 Cytosol aminopeptidase 3.369e-08 0.34
Q82323_9DELA Protease 3.392e-08 0.40
LEP_ECOLI lepB Signal peptidase I 9.314e-08 0.30
BACE1_HUMAN BACE1 Beta-secretase 1 9.64e-08 0.42
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 1.044e-07 0.33
Q9YQ12_9HIV1 protease Protease 1.067e-07 0.40
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 1.087e-07 0.28
NK2R_HUMAN TACR2 Substance-K receptor 1.548e-07 0.48
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 1.663e-07 0.32
MEN1_HUMAN MEN1 Menin 1.667e-07 0.48
CASP5_HUMAN CASP5 Caspase-5 1.698e-07 0.38
CATG_HUMAN CTSG Cathepsin G 1.983e-07 0.32
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 3.005e-07 0.30
MC5R_HUMAN MC5R Melanocortin receptor 5 3.209e-07 0.39
MMP8_HUMAN MMP8 Neutrophil collagenase 3.961e-07 0.32
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 4.479e-07 0.32
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 4.959e-07 0.31
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 6.18e-07 0.34
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 8.417e-07 0.30
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 8.54e-07 0.38
Q82134_9DELA prt Protease 9.488e-07 0.40
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.93e-06 0.32
OXYR_HUMAN OXTR Oxytocin receptor 2.211e-06 0.31
V2R_HUMAN AVPR2 Vasopressin V2 receptor 2.31e-06 0.33
RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 3.231e-06 0.28
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 3.431e-06 0.29
UR2R_RAT Uts2r Urotensin-2 receptor 4.683e-06 0.38
CATL1_HUMAN CTSL Cathepsin L1 8.223e-06 0.36

Piflufolastat_F_18

FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 4.857e-166 0.75
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 3.141e-141 0.39
DYR_MOUSE Dhfr Dihydrofolate reductase 8.945e-141 0.41
GLUC_HUMAN GCG Glucagon 8.223e-131 0.35
TYSY_MOUSE Tyms Thymidylate synthase 4.278e-127 0.36
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.782e-96 0.45
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 2.857e-88 0.35
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 7.473e-84 0.34
FOLR1_HUMAN FOLR1 Folate receptor alpha 2.827e-80 0.39
TYSY_HUMAN TYMS Thymidylate synthase 3.795e-79 0.36
FOLR2_HUMAN FOLR2 Folate receptor beta 2.87e-75 0.39
Q9I056_PSEAE cpg2 Carboxypeptidase G2 7.381e-72 0.34
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 4.067e-69 0.35
DYR_LACCA folA Dihydrofolate reductase 9.49e-69 0.39
S19A1_HUMAN SLC19A1 Reduced folate transporter 1.324e-67 0.35
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.424e-62 0.37
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 1.138e-60 0.45
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 8.674e-58 0.36
DYR_HUMAN DHFR Dihydrofolate reductase 5.521e-55 0.41
DYR_ENTFC folA Dihydrofolate reductase 6.396e-54 0.36
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 1.839e-51 0.35
GGH_HUMAN GGH Gamma-glutamyl hydrolase 2.936e-51 0.34
E2QDN0_ECOLX thyA Thymidylate synthase 9.051e-44 0.33
TYSY_LACCA thyA Thymidylate synthase 2.494e-42 0.41
GLR_HUMAN GCGR Glucagon receptor 4.141e-39 0.35
FOLC_ECOLI folC Dihydrofolate synthase/folylpolyglutamate synthase 5.748e-39 0.31
TYSY_RAT Tyms Thymidylate synthase 2.146e-38 0.33
MTDC_HUMAN MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 4.754e-38 0.30
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.789e-36 0.41
METH_HUMAN MTR Methionine synthase 1.253e-35 0.29
E2R517_CANLF GCGR Glucagon receptor 1.71e-35 0.28
DLG4_HUMAN DLG4 Disks large homolog 4 3.049e-34 0.30
HMGB1_HUMAN HMGB1 High mobility group protein B1 2.3e-28 0.35
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 4.869e-24 0.33
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.608e-23 0.38
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 4.377e-23 0.28
EGLN2_HUMAN EGLN2 Egl nine homolog 2 9.733e-21 0.35
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.253e-20 0.33
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 3.497e-20 0.39
C3SWJ7_ECOLX thyA Thymidylate synthase 7.816e-20 0.35
COMT_PIG COMT Catechol O-methyltransferase 1.254e-19 0.33
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 1.387e-19 0.30
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 1.608e-19 0.31
DYR_CHICK DHFR Dihydrofolate reductase 3.283e-19 0.35
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 3.304e-19 0.37
DYR_RAT Dhfr Dihydrofolate reductase 1.661e-18 0.39
LIPL_HUMAN LPL Lipoprotein lipase 6.556e-18 0.28
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 4.426e-17 0.37
LY96_HUMAN LY96 Lymphocyte antigen 96 1.11e-16 0.32
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.11e-16 0.33
DRD1_PIG DRD1 D(1A) dopamine receptor 6.106e-15 0.46
HPPD_RAT Hpd 4-hydroxyphenylpyruvate dioxygenase 1.743e-14 0.32
THAS_RAT Tbxas1 Thromboxane-A synthase 1.578e-13 0.36
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 3.294e-13 0.30
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 4.865e-13 0.35
DYR_MYCTU folA Dihydrofolate reductase 6.275e-13 0.35
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 6.938e-13 0.35
DYR_BOVIN DHFR Dihydrofolate reductase 1.511e-11 0.35
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 1.78e-11 0.31
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.758e-11 0.39
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 9.024e-11 0.31
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.469e-10 0.38
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 1.609e-10 0.33
Q81R22_BACAN dfrA Dihydrofolate reductase 1.995e-10 0.38
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 2.131e-10 0.30
CBPB2_HUMAN CPB2 Carboxypeptidase B2 2.147e-10 0.36
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 2.415e-10 0.42
CFAB_HUMAN CFB Complement factor B 2.717e-10 0.31
ENTK_HUMAN TMPRSS15 Enteropeptidase 3.837e-10 0.32
Q6DMN0_TOXGO CPL Cathepsin L 4.084e-10 0.29
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 4.888e-10 0.29
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 5.259e-10 0.38
CASP1_HUMAN CASP1 Caspase-1 7.737e-10 0.35
FURIN_HUMAN FURIN Furin 8.537e-10 0.34
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 9.852e-10 0.28
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.06e-09 0.34
HDAC9_HUMAN HDAC9 Histone deacetylase 9 6.58e-09 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 7.623e-09 0.38
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.037e-08 0.37
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.043e-08 0.29
GLR_RAT Gcgr Glucagon receptor 1.28e-08 0.31
DYR_PNECA Dihydrofolate reductase 2.888e-08 0.35
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 3.182e-08 0.30
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 5.123e-08 0.37
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 5.357e-08 0.36
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.858e-08 0.33
EGLN1_HUMAN EGLN1 Egl nine homolog 1 9.65e-08 0.31
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 9.981e-08 0.31
GLR_MOUSE Gcgr Glucagon receptor 1.041e-07 0.31
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 2.825e-07 0.35
CAH2_HUMAN CA2 Carbonic anhydrase 2 6.552e-07 0.42
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.608e-07 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 9.054e-07 0.31
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 9.298e-07 0.30
Q9YQ30_9PLVG HIV-1 protease HIV-1 protease 1.019e-06 0.29
HDAC1_RAT Hdac1 Histone deacetylase 1 1.175e-06 0.32
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.77e-06 0.29
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 2.957e-06 0.34
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.06e-06 0.44
MMP12_HUMAN MMP12 Macrophage metalloelastase 4.164e-06 0.35
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 4.38e-06 0.34
NEP_RABIT MME Neprilysin 4.768e-06 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.009e-06 0.37
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 5.061e-06 0.34
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.638e-06 0.41
DRD3_HUMAN DRD3 D(3) dopamine receptor 7.255e-06 0.46
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 7.906e-06 0.36
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 8.304e-06 0.31
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 8.573e-06 0.33

Dexamethasone_acetate

ATTY_RAT Tat Tyrosine aminotransferase 5.182e-156 0.59
GCR_RAT Nr3c1 Glucocorticoid receptor 7.467e-100 0.79
Q690N0_BOVIN PGR Progesterone receptor 1.525e-58 0.79
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.287e-47 0.79
GCR_MOUSE Nr3c1 Glucocorticoid receptor 5.879e-25 0.55
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.913e-22 0.40
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.673e-11 0.35
GLNA_HUMAN GLUL Glutamine synthetase 4.673e-11 0.35
IL6_HUMAN IL6 Interleukin-6 7.759e-09 0.35
MMP1_HUMAN MMP1 Interstitial collagenase 2.549e-08 0.61
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.826e-06 0.29

Lypressin

NTR2_HUMAN NTSR2 Neurotensin receptor type 2 5.616e-138 0.38
V2R_PIG AVPR2 Vasopressin V2 receptor 8.984e-135 0.57
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 6.724e-106 0.38
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 2.551e-103 0.38
NTR1_RAT Ntsr1 Neurotensin receptor type 1 7.879e-103 0.39
OPRM_RAT Oprm1 Mu-type opioid receptor 2.626e-99 0.44
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 6.764e-95 0.33
OPRD_RAT Oprd1 Delta-type opioid receptor 1.167e-86 0.44
PRSS8_HUMAN PRSS8 Prostasin 1.706e-82 0.36
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.51e-81 0.44
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.671e-79 0.82
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 1.82e-77 0.37
V2R_BOVIN AVPR2 Vasopressin V2 receptor 7.322e-76 0.49
Q5D7U5_CHICK OXTR Oxytocin-like receptor 3.931e-75 0.60
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.521e-73 0.44
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.558e-68 0.52
SORT_HUMAN SORT1 Sortilin 5.615e-67 0.36
OXYR_HUMAN OXTR Oxytocin receptor 2.594e-61 0.78
SSR5_RAT Sstr5 Somatostatin receptor type 5 6.582e-59 0.34
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.165e-58 0.39
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 5.256e-58 0.38
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.3e-57 0.39
F1SH20_PIG TRHDE Uncharacterized protein 2.716e-52 0.32
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 5.652e-52 0.34
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 7.591e-50 0.37
IDE_MOUSE Ide Insulin-degrading enzyme 1.225e-49 0.31
TRY1_BOVIN Cationic trypsin 1.667e-47 0.38
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 2.518e-45 0.82
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.141e-44 0.37
V2R_HUMAN AVPR2 Vasopressin V2 receptor 4.062e-43 0.82
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 3.643e-40 0.32
SURA_ECOLI surA Chaperone SurA 1.302e-39 0.31
UR2R_RAT Uts2r Urotensin-2 receptor 2.575e-38 0.46
MC4R_MOUSE Mc4r Melanocortin receptor 4 1.413e-34 0.36
OXYR_MOUSE Oxtr Oxytocin receptor 3.221e-34 0.55
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 4.539e-32 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 1.167e-31 0.46
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.729e-31 0.34
ITA3_HUMAN ITGA3 Integrin alpha-3 8.172e-31 0.35
THRB_HUMAN F2 Prothrombin 2.081e-30 0.39
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.662e-29 0.38
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.31e-29 0.34
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.285e-28 0.35
A4HSF7_LEIIN TRYR Trypanothione reductase 1.52e-28 0.35
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 3.334e-28 0.28
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 8.825e-28 0.42
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.812e-27 0.37
ITA5_HUMAN ITGA5 Integrin alpha-5 2.164e-27 0.35
MC3R_MOUSE Mc3r Melanocortin receptor 3 8.786e-26 0.35
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.212e-25 0.36
FSHR_RAT Fshr Follicle-stimulating hormone receptor 6.589e-25 0.31
NK2R_MESAU TACR2 Substance-K receptor 1.468e-24 0.32
ITAV_HUMAN ITGAV Integrin alpha-V 4.093e-24 0.37
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 5.679e-24 0.39
V1AR_RAT Avpr1a Vasopressin V1a receptor 6.574e-24 0.82
NRP1_RAT Nrp1 Neuropilin-1 1.442e-23 0.31
IDE_HUMAN IDE Insulin-degrading enzyme 5.002e-23 0.33
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 6.116e-23 0.28
TRY3_HUMAN PRSS3 Trypsin-3 2.833e-22 0.32
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 6.147e-22 0.32
ACE_HUMAN ACE Angiotensin-converting enzyme 1.507e-21 0.40
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 2.119e-21 0.41
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 4.524e-21 0.39
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 5.059e-21 0.35
ITB3_HUMAN ITGB3 Integrin beta-3 8.953e-21 0.37
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 9.071e-21 0.35
RENI_RAT Ren1 Renin 1.037e-20 0.31
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.274e-20 0.29
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.94e-20 0.39
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.006e-19 0.70
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 3.412e-19 0.30
OXYR_RAT Oxtr Oxytocin receptor 5.809e-19 0.70
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.098e-18 0.39
NK1R_CAVPO TACR1 Substance-P receptor 1.18e-18 0.39
NK2R_RAT Tacr2 Substance-K receptor 1.464e-18 0.37
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 1.834e-18 0.31
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 2.139e-18 0.29
ITB5_HUMAN ITGB5 Integrin beta-5 4.72e-18 0.35
LGMN_HUMAN LGMN Legumain 5.592e-18 0.32
ACE_RABIT ACE Angiotensin-converting enzyme 5.665e-18 0.36
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 8.104e-18 0.28
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 9.148e-18 0.42
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.157e-17 0.36
NK2R_RABIT TACR2 Substance-K receptor 2.592e-17 0.30
NK1R_RAT Tacr1 Substance-P receptor 2.679e-17 0.41
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 1.11e-16 0.32
O07911_STAAU agrC AgrC 7.772e-16 0.30
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 8.882e-16 0.31
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.998e-15 0.38
PLMN_HUMAN PLG Plasminogen 2.109e-15 0.38
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 2.22e-15 0.35
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.553e-15 0.32
AMPL_HUMAN LAP3 Cytosol aminopeptidase 7.772e-15 0.31
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 3.242e-14 0.35
O57585_DANRE oprd1a Opioid receptor homologue 3.242e-14 0.35
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 5.74e-14 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 7.039e-14 0.37
TRY1_HUMAN PRSS1 Trypsin-1 1.292e-13 0.32
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 2.559e-13 0.46
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 3.3e-13 0.35
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 5.125e-13 0.28
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 5.125e-13 0.28
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 6.387e-13 0.35
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.222e-12 0.37
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 1.446e-12 0.41
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.018e-12 0.32
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 2.885e-12 0.40
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 3.497e-12 0.30
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 3.702e-12 0.29
MC5R_MOUSE Mc5r Melanocortin receptor 5 3.986e-12 0.33
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 4.171e-12 0.33
AGRA_STAAU agrA Accessory gene regulator protein A 4.446e-12 0.29
PRTN3_HUMAN PRTN3 Myeloblastin 5.897e-12 0.38
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.5e-11 0.42
MC4R_HUMAN MC4R Melanocortin receptor 4 1.59e-11 0.36
ITB1_HUMAN ITGB1 Integrin beta-1 1.11e-10 0.35
Q91H74_9FLAV Genome polyprotein 2.29e-10 0.31
ITB6_HUMAN ITGB6 Integrin beta-6 2.526e-10 0.35
V2R_RAT Avpr2 Vasopressin V2 receptor 2.861e-10 0.70
FA10_BOVIN F10 Coagulation factor X 2.9e-10 0.32
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 3.533e-10 0.30
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 4.254e-10 0.37
TAT_HV1H2 tat Protein Tat 4.884e-10 0.29
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 8.949e-10 0.31
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.089e-09 0.31
NK3R_RAT Tacr3 Neuromedin-K receptor 1.663e-09 0.37
GRIA1_HUMAN GRIA1 Glutamate receptor 1 6.9e-09 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.949e-09 0.31
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 8.229e-09 0.34
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 8.661e-09 0.33
NK3R_CAVPO TACR3 Neuromedin-K receptor 2.007e-08 0.31
NTR2_RAT Ntsr2 Neurotensin receptor type 2 2.205e-08 0.32
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 5.571e-08 0.33
MC3R_HUMAN MC3R Melanocortin receptor 3 6.088e-08 0.32
MEN1_HUMAN MEN1 Menin 6.291e-08 0.33
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 8.97e-08 0.32
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.084e-07 0.37
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 1.218e-07 0.34
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 1.267e-07 0.34
Q9R297_RAT Mlnr Motilin receptor 1.511e-07 0.29
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 1.679e-07 0.34
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.87e-07 0.31
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.938e-07 0.40
PLMN_RAT Plg Plasminogen 2.032e-07 0.30
RENI_HUMAN REN Renin 2.137e-07 0.34
CATG_HUMAN CTSG Cathepsin G 4.263e-07 0.29
ACE_MOUSE Ace Angiotensin-converting enzyme 5.622e-07 0.28
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 7.595e-07 0.33
KLK5_HUMAN KLK5 Kallikrein-5 1.102e-06 0.31
ADAM8_HUMAN ADAM8 Disintegrin and metalloproteinase domain-containing protein 8 1.414e-06 0.29
Q9S446_STAAU srtA Class A sortase SrtA 2.621e-06 0.32
Q82323_9DELA Protease 2.726e-06 0.30
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 4.251e-06 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 5.274e-06 0.35
TPA_HUMAN PLAT Tissue-type plasminogen activator 5.52e-06 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.755e-06 0.32

Dexamethasone_metasulfobenzoate

ATTY_RAT Tat Tyrosine aminotransferase 1.009e-136 0.51
GCR_RAT Nr3c1 Glucocorticoid receptor 1.399e-83 0.66
Q690N0_BOVIN PGR Progesterone receptor 1.885e-45 0.66
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.824e-41 0.73
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.112e-13 0.47
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.05e-10 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.274e-09 0.30
GLNA_HUMAN GLUL Glutamine synthetase 1.274e-09 0.30
IL6_HUMAN IL6 Interleukin-6 1.044e-07 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 3.365e-07 0.52

Nicotinamide_riboside

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 8.853e-118 0.37
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 8.007e-76 0.40
PANE_ECOLI panE 2-dehydropantoate 2-reductase 3.241e-65 0.41
CDD_MOUSE Cda Cytidine deaminase 2.993e-56 0.37
LEG9_HUMAN LGALS9 Galectin-9 4.711e-48 0.37
CDD_HUMAN CDA Cytidine deaminase 3.591e-39 0.37
ALDH2_RAT Aldh2 Aldehyde dehydrogenase, mitochondrial 2.222e-36 0.29
RASN_HUMAN NRAS GTPase NRas 1.215e-35 0.28
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 4.567e-35 0.31
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 3.2e-33 0.34
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.006e-31 0.33
B4EH87_BURCJ Lectin 3.983e-31 0.33
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.454e-27 0.37
MANBA_HUMAN MANBA Beta-mannosidase 1.481e-26 0.33
ADA_MOUSE Ada Adenosine deaminase 1.669e-26 0.33
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 1.351e-25 0.37
LEG3_HUMAN LGALS3 Galectin-3 1.86e-23 0.37
AL1A7_RAT Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 2e-23 0.29
LEG1_HUMAN LGALS1 Galectin-1 1.057e-22 0.37
KITH_VZVD TK Thymidine kinase 3.93e-20 0.31
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 1.202e-19 0.38
HXK2_HUMAN HK2 Hexokinase-2 1.11e-16 0.37
FGF1_HUMAN FGF1 Fibroblast growth factor 1 2.22e-16 0.28
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 3.331e-16 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 6.661e-16 0.34
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 8.882e-16 0.30
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 1.221e-15 0.29
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 2.998e-15 0.38
HXK1_HUMAN HK1 Hexokinase-1 3.442e-15 0.37
AA1R_CHICK ADORA1 Adenosine receptor A1 6.75e-14 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.225e-13 0.28
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.539e-12 0.36
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.701e-12 0.36
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 5.427e-12 0.29
CD69_HUMAN CD69 Early activation antigen CD69 1.196e-11 0.28
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.627e-10 0.36
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.009e-09 0.28
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.469e-09 0.31
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 3.838e-09 0.30
CAH2_HUMAN CA2 Carbonic anhydrase 2 8.278e-09 0.36
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 8.292e-09 0.29
ADK_HUMAN ADK Adenosine kinase 1.707e-08 0.36
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 6.82e-08 0.31
ADA_HUMAN ADA Adenosine deaminase 1.634e-06 0.29
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.123e-06 0.30
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 5.176e-06 0.36
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 5.619e-06 0.30
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 7.031e-06 0.36

Mavacamten

GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.678e-117 0.37
ACE_MOUSE Ace Angiotensin-converting enzyme 5.076e-40 0.31
KCNB2_HUMAN KCNB2 Potassium voltage-gated channel subfamily B member 2 4.749e-37 0.29
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 9.719e-24 0.29
IDHC_HUMAN IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 7.825e-22 0.34
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 3.184e-20 0.32
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.758e-19 0.31
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.152e-18 0.31
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 4.308e-18 0.36
DPO3_BACSU polC DNA polymerase III PolC-type 1.172e-17 0.30
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.11e-16 0.33
LDHB_HUMAN LDHB L-lactate dehydrogenase B chain 8.549e-15 0.32
CALM_BOVIN CALM Calmodulin 8.327e-12 0.32
LDHA_HUMAN LDHA L-lactate dehydrogenase A chain 2.408e-10 0.34
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 3.484e-10 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.284e-09 0.33
AA2BR_MOUSE Adora2b Adenosine receptor A2b 2.988e-09 0.29
VE1_HPV11 E1 Replication protein E1 1.429e-08 0.30
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 3.532e-08 0.36
PA_I34A1 PA Polymerase acidic protein 6.472e-08 0.33
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.387e-08 0.29
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 1.034e-07 0.32
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 1.386e-07 0.36
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 4.733e-07 0.32
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 5.904e-07 0.32
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 9.1e-07 0.36
OXDA_MOUSE Dao D-amino-acid oxidase 1.093e-06 0.32
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.328e-06 0.30
PEPT1_DERPT DERP1 Peptidase 1 1.657e-06 0.29
DUT_HUMAN DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 2.709e-06 0.30
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 3.073e-06 0.30
SCAF_HCMVA UL80 Capsid scaffolding protein 3.904e-06 0.33
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 6.109e-06 0.31
CBPA1_BOVIN CPA1 Carboxypeptidase A1 9.178e-06 0.30

Solriamfetol

NEP_RABIT MME Neprilysin 2.784e-116 0.38
AMPN_PIG ANPEP Aminopeptidase N 3.366e-114 0.50
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.66e-88 0.42
AMPL_PIG LAP3 Cytosol aminopeptidase 1.855e-86 0.40
NEP_RAT Mme Neprilysin 1.855e-86 0.41
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 4.695e-80 0.40
AMPN_HUMAN ANPEP Aminopeptidase N 1.494e-76 0.46
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.499e-76 0.44
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 9.689e-75 0.42
AMP1_PLAFQ M1 family aminopeptidase 1.744e-74 0.39
NEP_MOUSE Mme Neprilysin 3.384e-73 0.41
AMPB_RAT Rnpep Aminopeptidase B 3.677e-73 0.40
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 3.911e-73 0.40
AMPL_HUMAN LAP3 Cytosol aminopeptidase 1.734e-70 0.46
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 4.987e-68 0.47
NK1R_RAT Tacr1 Substance-P receptor 1.948e-65 0.56
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 8.825e-65 0.47
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.28e-64 0.48
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 7.054e-63 0.37
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 5.913e-62 0.37
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.042e-61 0.40
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.132e-61 0.32
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.597e-57 0.35
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.505e-57 0.34
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 9.047e-57 0.34
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 3.154e-56 0.35
KLK8_HUMAN KLK8 Kallikrein-8 4.397e-54 0.34
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.862e-53 0.44
KYNU_HUMAN KYNU Kynureninase 8.119e-52 0.31
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 9.365e-52 0.32
GLT_PYRHO Glutamate transporter homolog 1.67e-51 0.41
PAPA1_CARPA Papain 4.945e-51 0.38
NEP_HUMAN MME Neprilysin 1.105e-50 0.40
CATL1_BOVIN CTSL Cathepsin L1 6.726e-50 0.38
THER_BACTH npr Thermolysin 7.914e-50 0.40
KLK4_HUMAN KLK4 Kallikrein-4 1.272e-49 0.34
Q72874_9HIV1 pol Pol polyprotein 4.586e-48 0.40
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.037e-47 0.38
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 1.47e-47 0.41
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.968e-46 0.34
AMPB_MOUSE Rnpep Aminopeptidase B 1.634e-45 0.36
AMPL_BOVIN LAP3 Cytosol aminopeptidase 1.634e-45 0.36
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.159e-45 0.58
Q99P97_RAT Histone deacetylase 6 1.389e-44 0.35
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.202e-43 0.36
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.264e-41 0.41
CANX_CHICK Calpain-1 catalytic subunit 3.192e-41 0.33
MURI_LACFE murI Glutamate racemase 4.048e-41 0.33
TY3H_RAT Th Tyrosine 3-monooxygenase 4.673e-41 0.33
OPRM_RAT Oprm1 Mu-type opioid receptor 1.842e-39 0.47
CATB_RAT Ctsb Cathepsin B 3.665e-39 0.31
KLK2_HUMAN KLK2 Kallikrein-2 2.101e-37 0.34
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 2.435e-37 0.30
POLG_HRV14 Genome polyprotein 2.707e-37 0.30
Q6IE76_BOVIN FDFT1 FDFT1 protein 1.046e-36 0.29
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 3.729e-36 0.35
SPLB_STAAU splB Serine protease SplB 3.875e-36 0.29
Q8ILP4_PLAF7 Pantothenate kinase, putative 8.333e-36 0.28
CATH_RAT Ctsh Pro-cathepsin H 8.572e-36 0.30
CATJ_RAT Ctsj Cathepsin J 8.572e-36 0.30
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.338e-33 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.875e-33 0.47
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.951e-33 0.40
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.841e-33 0.40
OPRD_RAT Oprd1 Delta-type opioid receptor 7.229e-33 0.39
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.028e-30 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.146e-30 0.41
NEP_PIG MME Neprilysin 6.583e-30 0.31
CATC_RAT Ctsc Dipeptidyl peptidase 1 8.649e-30 0.30
NK3R_CAVPO TACR3 Neuromedin-K receptor 1.014e-29 0.38
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 1.108e-29 0.35
ACE_HUMAN ACE Angiotensin-converting enzyme 1.411e-29 0.38
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 1.427e-29 0.29
CYSP_TRYCR Cruzipain 3.94e-29 0.38
MCA2_TRYBB MCA2 Metacaspase 6.416e-29 0.32
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 8.115e-29 0.32
CATL1_HUMAN CTSL Cathepsin L1 1.257e-28 0.38
KLK1_HUMAN KLK1 Kallikrein-1 1.266e-28 0.33
NK2R_MESAU TACR2 Substance-K receptor 1.334e-28 0.34
AMPB_HUMAN RNPEP Aminopeptidase B 2.597e-28 0.41
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 3.921e-28 0.32
PHLC_BACCE plc Phospholipase C 5.847e-28 0.29
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 7.58e-28 0.34
CATB_BOVIN CTSB Cathepsin B 8.254e-28 0.33
ACE_MOUSE Ace Angiotensin-converting enzyme 1.477e-27 0.32
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.697e-27 0.34
UROK_RAT Plau Urokinase-type plasminogen activator 1.567e-26 0.33
Q3HTL5_PLAFA fp2B Falcipain 2B 1.669e-26 0.33
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 2.173e-26 0.33
PEPA1_PENJA Penicillopepsin-1 2.983e-26 0.30
OPRM_CAVPO OPRM1 Mu-type opioid receptor 7.035e-26 0.38
MMP8_RAT Mmp8 Neutrophil collagenase 7.328e-26 0.29
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 8.039e-26 0.40
BLAB_BACCE Metallo-beta-lactamase type 2 1.914e-25 0.29
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.958e-25 0.39
CATB_HUMAN CTSB Cathepsin B 4.752e-25 0.38
BLA1_STEMA Metallo-beta-lactamase L1 type 3 8.513e-25 0.33
HPGDS_MOUSE Hpgds Hematopoietic prostaglandin D synthase 1.132e-24 0.30
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.547e-24 0.33
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 1.725e-24 0.33
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 2.426e-24 0.36
OPRD_MOUSE Oprd1 Delta-type opioid receptor 4.214e-24 0.38
CATZ_RAT Ctsz Cathepsin Z 5.245e-24 0.30
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 6.243e-24 0.29
Q9NBD4_PLAFA Cysteine protease falcipain-2 7.498e-24 0.29
HDAC1_RAT Hdac1 Histone deacetylase 1 1.079e-23 0.31
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 1.313e-23 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 4.712e-23 0.40
Q43014_PRUAV Beta-glucosidase 4.989e-23 0.28
HISX_BRUSU hisD Histidinol dehydrogenase 1.177e-22 0.34
ACE_RAT Ace Angiotensin-converting enzyme 1.229e-22 0.36
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.371e-22 0.40
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 6.042e-22 0.31
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 2.046e-21 0.31
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.184e-21 0.40
KLKB1_HUMAN KLKB1 Plasma kallikrein 2.4e-21 0.33
HISX_ECOLI hisD Histidinol dehydrogenase 2.491e-21 0.34
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 2.751e-21 0.41
TAT_HV1H2 tat Protein Tat 3.433e-21 0.34
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 5.63e-21 0.29
Q6RY99_RAT Tetraspanin 1.445e-20 0.29
TY3H_HUMAN TH Tyrosine 3-monooxygenase 1.948e-20 0.33
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.396e-20 0.37
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 1.007e-19 0.31
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 1.145e-19 0.31
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.623e-19 0.47
Q4U254_9ENTO protease Protease 3.374e-19 0.34
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 4.378e-19 0.29
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 4.378e-19 0.29
Q9Z1J7_RAT Slc1a5 Amino acid transporter 4.607e-19 0.29
CSK_HUMAN CSK Tyrosine-protein kinase CSK 6.893e-19 0.32
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 8.22e-19 0.36
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.262e-18 0.34
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.468e-18 0.36
PA_I34A1 PA Polymerase acidic protein 1.477e-18 0.34
MMP9_RAT Mmp9 Matrix metalloproteinase-9 1.636e-18 0.29
ECE1_RAT Ece1 Endothelin-converting enzyme 1 2.162e-18 0.34
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 2.265e-18 0.36
CMA1_HUMAN CMA1 Chymase 3.662e-18 0.38
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 4.879e-18 0.29
GRIA2_RAT Gria2 Glutamate receptor 2 6.02e-18 0.37
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 7.502e-18 0.28
LY96_HUMAN LY96 Lymphocyte antigen 96 8.756e-18 0.34
CATK_RABIT CTSK Cathepsin K 9.909e-18 0.32
GRIA3_RAT Gria3 Glutamate receptor 3 9.995e-18 0.33
PA_I000X PA Polymerase acidic protein 1.882e-17 0.33
ASAH1_HUMAN ASAH1 Acid ceramidase 2.118e-17 0.31
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.22e-16 0.33
CATH_HUMAN CTSH Pro-cathepsin H 2.22e-16 0.31
CTRA_BOVIN Chymotrypsinogen A 2.22e-16 0.36
EST1_RABIT Liver carboxylesterase 1 2.22e-16 0.34
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.22e-16 0.31
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 3.331e-16 0.38
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 4.441e-16 0.34
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 6.661e-16 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.772e-16 0.32
NK1R_CAVPO TACR1 Substance-P receptor 1.11e-15 0.36
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.332e-15 0.33
GRIA4_RAT Gria4 Glutamate receptor 4 1.554e-15 0.33
FURIN_HUMAN FURIN Furin 1.776e-15 0.33
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 2.998e-15 0.31
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 3.442e-15 0.33
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 3.775e-15 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 4.885e-15 0.48
UROK_MOUSE Plau Urokinase-type plasminogen activator 6.328e-15 0.33
CATK_HUMAN CTSK Cathepsin K 9.215e-15 0.38
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.199e-14 0.36
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.532e-14 0.50
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 4.163e-14 0.33
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 4.263e-14 0.39
MGLL_RAT Mgll Monoglyceride lipase 5.107e-14 0.33
CATG_HUMAN CTSG Cathepsin G 6.473e-14 0.31
BLA2_BACCE blm Metallo-beta-lactamase type 2 8.094e-14 0.44
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 9.504e-14 0.30
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.448e-13 0.37
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.463e-13 0.33
MMP1_HUMAN MMP1 Interstitial collagenase 1.648e-13 0.37
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 1.884e-13 0.29
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 1.884e-13 0.29
AMPN_MOUSE Anpep Aminopeptidase N 2.602e-13 0.36
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 2.862e-13 0.29
KLK5_HUMAN KLK5 Kallikrein-5 3.426e-13 0.33
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.776e-13 0.38
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 3.922e-13 0.29
PA2GF_MOUSE Pla2g2f Group IIF secretory phospholipase A2 3.922e-13 0.29
MDM4_HUMAN MDM4 Protein Mdm4 3.963e-13 0.35
TYRO_HUMAN TYR Tyrosinase 4.915e-13 0.34
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 5.123e-13 0.30
BODG_PSESK Gamma-butyrobetaine dioxygenase 5.125e-13 0.28
Q6FTL6_CANGA NCE103 Carbonic anhydrase 6.639e-13 0.31
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 7.058e-13 0.29
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 1.69e-12 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.168e-12 0.42
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.501e-12 0.33
GRIA1_RAT Gria1 Glutamate receptor 1 3.801e-12 0.33
PA2GD_MOUSE Pla2g2d Group IID secretory phospholipase A2 9.7e-12 0.29
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 1.226e-11 0.35
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.228e-11 0.39
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 1.343e-11 0.34
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.559e-11 0.37
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 1.676e-11 0.31
ACE_RABIT ACE Angiotensin-converting enzyme 1.965e-11 0.38
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 2.335e-11 0.33
A5A4K8_RABIT MLNR Motilin receptor 2.353e-11 0.32
O31048_PORGN DPP IV Dipeptidyl peptidase IV 3.524e-11 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.863e-11 0.34
KPCI_HUMAN PRKCI Protein kinase C iota type 7.9e-11 0.33
SSPA_STAAU sspA Glutamyl endopeptidase 8.878e-11 0.29
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 9.696e-11 0.36
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 9.914e-11 0.38
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.019e-10 0.32
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.061e-10 0.38
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 1.105e-10 0.29
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.72e-10 0.37
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 2.079e-10 0.42
PGTB1_BOVIN PGGT1B Geranylgeranyl transferase type-1 subunit beta 2.264e-10 0.35
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.659e-10 0.30
NK3R_HUMAN TACR3 Neuromedin-K receptor 3.922e-10 0.38
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 3.929e-10 0.41
P2RX4_RAT P2rx4 P2X purinoceptor 4 4.066e-10 0.34
MMP2_HUMAN MMP2 72 kDa type IV collagenase 4.071e-10 0.36
GALR2_RAT Galr2 Galanin receptor type 2 4.398e-10 0.29
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.692e-10 0.35
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 4.705e-10 0.33
Q7ZJM1_9HIV1 pol Integrase 5.682e-10 0.31
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 6.557e-10 0.33
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 7.541e-10 0.29
MMP3_HUMAN MMP3 Stromelysin-1 8.356e-10 0.35
UROK_HUMAN PLAU Urokinase-type plasminogen activator 8.384e-10 0.38
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 9.181e-10 0.28
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 9.414e-10 0.31
ELAS_PSEAE lasB Elastase 1.094e-09 0.34
CAN_CANAL NCE103 Carbonic anhydrase 2.315e-09 0.31
O07911_STAAU agrC AgrC 3.277e-09 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.278e-09 0.30
PA2GF_HUMAN PLA2G2F Group IIF secretory phospholipase A2 3.598e-09 0.29
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 3.598e-09 0.29
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.784e-09 0.37
CATS_HUMAN CTSS Cathepsin S 5.015e-09 0.38
GRIA1_HUMAN GRIA1 Glutamate receptor 1 6.578e-09 0.30
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 7.167e-09 0.33
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 7.167e-09 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 7.167e-09 0.33
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 9.968e-09 0.31
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.047e-08 0.36
TRY1_HUMAN PRSS1 Trypsin-1 1.25e-08 0.33
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 1.254e-08 0.29
MC4R_MOUSE Mc4r Melanocortin receptor 4 1.436e-08 0.32
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 1.607e-08 0.28
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.655e-08 0.32
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.881e-08 0.33
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.881e-08 0.33
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 1.881e-08 0.33
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.881e-08 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 1.971e-08 0.38
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.609e-08 0.33
IL2RA_MOUSE Il2ra Interleukin-2 receptor subunit alpha 3.032e-08 0.29
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.782e-08 0.30
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 4.257e-08 0.37
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 4.403e-08 0.33
Q9YQ12_9HIV1 protease Protease 4.446e-08 0.35
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 4.539e-08 0.37
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.661e-08 0.41
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 4.714e-08 0.37
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 4.778e-08 0.32
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 5.975e-08 0.30
SEPR_HUMAN FAP Prolyl endopeptidase FAP 6.479e-08 0.37
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 6.59e-08 0.35
MMP8_HUMAN MMP8 Neutrophil collagenase 6.971e-08 0.39
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 7.139e-08 0.40
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 7.347e-08 0.31
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 8.953e-08 0.36
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 9.381e-08 0.33
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.022e-07 0.33
PA2GE_MOUSE Pla2g2e Group IIE secretory phospholipase A2 1.031e-07 0.29
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.141e-07 0.36
THRB_HUMAN F2 Prothrombin 1.152e-07 0.37
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.761e-07 0.32
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.848e-07 0.33
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 1.848e-07 0.33
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 1.848e-07 0.33
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 1.986e-07 0.30
CTRB_BOVIN Chymotrypsinogen B 2.077e-07 0.29
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 2.38e-07 0.30
NK1R_HUMAN TACR1 Substance-P receptor 2.62e-07 0.47
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 2.651e-07 0.30
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.205e-07 0.29
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 3.211e-07 0.32
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 3.409e-07 0.33
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 3.814e-07 0.30
PLMN_RAT Plg Plasminogen 3.963e-07 0.29
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 4.293e-07 0.34
PA21B_MOUSE Pla2g1b Phospholipase A2 4.905e-07 0.29
PA2GE_HUMAN PLA2G2E Group IIE secretory phospholipase A2 4.905e-07 0.29
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 5.052e-07 0.32
DPP4_PIG DPP4 Dipeptidyl peptidase 4 5.342e-07 0.36
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 5.944e-07 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 7.458e-07 0.31
ALBU_BOVIN ALB Serum albumin 8.676e-07 0.30
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 8.979e-07 0.33
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 9.396e-07 0.29
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 9.875e-07 0.33
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 9.875e-07 0.33
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 9.875e-07 0.33
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.037e-06 0.31
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.14e-06 0.29
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 1.147e-06 0.31
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.195e-06 0.29
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.195e-06 0.29
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.195e-06 0.29
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.195e-06 0.29
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.195e-06 0.29
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.195e-06 0.29
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.195e-06 0.29
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.195e-06 0.29
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.195e-06 0.29
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.195e-06 0.29
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.195e-06 0.29
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.195e-06 0.29
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.195e-06 0.29
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.195e-06 0.29
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.195e-06 0.29
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.195e-06 0.29
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.195e-06 0.29
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.195e-06 0.29
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.358e-06 0.30
ADA_HUMAN ADA Adenosine deaminase 1.389e-06 0.29
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.45e-06 0.30
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 1.507e-06 0.30
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 1.573e-06 0.29
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.574e-06 0.33
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 1.574e-06 0.33
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 1.574e-06 0.33
EST2_HUMAN CES2 Cocaine esterase 1.652e-06 0.32
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 1.698e-06 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.228e-06 0.33
OPRX_CAVPO OPRL1 Nociceptin receptor 2.32e-06 0.29
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.399e-06 0.30
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 2.417e-06 0.33
H9B8T9_CAPHI CTSB Cathepsin B 2.701e-06 0.37
FNTB_BOVIN FNTB Protein farnesyltransferase subunit beta 3.584e-06 0.31
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 3.596e-06 0.33
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 3.596e-06 0.33
CATC_HUMAN CTSC Dipeptidyl peptidase 1 3.675e-06 0.40
AOFB_RAT Maob Amine oxidase [flavin-containing] B 4.108e-06 0.40
A5H660_SCHMA HDAC8 Histone deacetylase 8 4.184e-06 0.35
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 4.735e-06 0.41
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.16e-06 0.28
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 5.201e-06 0.33
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 7.334e-06 0.33
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 7.334e-06 0.33
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 7.334e-06 0.33
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 7.334e-06 0.33
FEN1_HUMAN FEN1 Flap endonuclease 1 7.626e-06 0.31
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 8.196e-06 0.30
CASP3_HUMAN CASP3 Caspase-3 9.208e-06 0.35
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 9.211e-06 0.31
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 9.43e-06 0.32
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 9.531e-06 0.33
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 9.622e-06 0.33

Hydrocortisone_phosphate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.961e-109 0.77
Q690N0_BOVIN PGR Progesterone receptor 2.921e-62 0.51
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.229e-59 0.75
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.328e-55 0.51
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.826e-44 0.75
GCR_HUMAN NR3C1 Glucocorticoid receptor 8.555e-42 0.75
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.134e-40 0.51
CP19A_HUMAN CYP19A1 Aromatase 1.937e-39 0.42
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.452e-31 0.51
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 8.994e-29 0.37
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.795e-28 0.52
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 2.241e-25 0.51
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.138e-23 0.42
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.61e-23 0.38
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 4.722e-23 0.37
ANDR_RAT Ar Androgen receptor 1.048e-19 0.51
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.574e-19 0.30
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.753e-19 0.37
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.624e-18 0.51
GLNA_HUMAN GLUL Glutamine synthetase 4.441e-16 0.52
PRGR_RAT Pgr Progesterone receptor 2.22e-15 0.34
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.662e-15 0.38
PRGR_RABIT PGR Progesterone receptor 1.432e-14 0.40
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 8.3e-13 0.51
IL6_HUMAN IL6 Interleukin-6 8.449e-13 0.52
ANDR_MOUSE Ar Androgen receptor 9.683e-13 0.42
GCR_RAT Nr3c1 Glucocorticoid receptor 1.888e-12 0.52
MCR_HUMAN NR3C2 Mineralocorticoid receptor 9.088e-12 0.75
ERG2_YEAST ERG2 C-8 sterol isomerase 1.499e-10 0.42
ANDR_HUMAN AR Androgen receptor 2.728e-08 0.52
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.683e-08 0.62
MCR_RAT Nr3c2 Mineralocorticoid receptor 7.842e-08 0.49

Dotatate

SSR5_RAT Sstr5 Somatostatin receptor type 5 5.708e-107 0.65
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 2.62e-101 0.67
CD36_RAT Cd36 Platelet glycoprotein 4 6.847e-99 0.34
NK2R_RABIT TACR2 Substance-K receptor 5.544e-93 0.35
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.987e-88 0.41
MC3R_HUMAN MC3R Melanocortin receptor 3 2.065e-83 0.38
EDNRA_PIG EDNRA Endothelin-1 receptor 1.418e-79 0.42
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 2.146e-78 0.65
V2R_PIG AVPR2 Vasopressin V2 receptor 5.987e-78 0.36
OPRM_RAT Oprm1 Mu-type opioid receptor 6.044e-74 0.61
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 2.449e-70 0.36
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.818e-69 0.45
OPRM_CAVPO OPRM1 Mu-type opioid receptor 8.818e-68 0.45
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 6.695e-67 0.33
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.017e-65 0.36
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.447e-65 0.35
OPRD_RAT Oprd1 Delta-type opioid receptor 3.341e-65 0.58
O07911_STAAU agrC AgrC 3.557e-65 0.40
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.28e-61 0.35
EDNRA_MOUSE Ednra Endothelin-1 receptor 4.012e-61 0.36
NK2R_MESAU TACR2 Substance-K receptor 8.955e-59 0.39
MC4R_HUMAN MC4R Melanocortin receptor 4 1.289e-54 0.44
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 1.181e-52 0.67
UR2R_RAT Uts2r Urotensin-2 receptor 1.93e-52 0.62
V2R_BOVIN AVPR2 Vasopressin V2 receptor 2.589e-49 0.33
NK2R_HUMAN TACR2 Substance-K receptor 2.401e-48 0.41
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 7.072e-48 0.46
GRPR_RAT Grpr Gastrin-releasing peptide receptor 4.591e-47 0.34
MC4R_MOUSE Mc4r Melanocortin receptor 4 9.107e-47 0.36
SURA_ECOLI surA Chaperone SurA 3.859e-43 0.34
NK2R_RAT Tacr2 Substance-K receptor 1.508e-42 0.36
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 4.894e-42 0.34
Q5D7U5_CHICK OXTR Oxytocin-like receptor 9.796e-42 0.33
OXYR_HUMAN OXTR Oxytocin receptor 9.204e-40 0.39
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 2.294e-39 0.39
NTR1_RAT Ntsr1 Neurotensin receptor type 1 3e-39 0.32
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 5.284e-39 0.33
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1.393e-38 0.29
EDNRB_RAT Ednrb Endothelin receptor type B 7.25e-38 0.34
PSB6_YEAST PRE7 Proteasome subunit beta type-6 1.059e-37 0.30
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 1.114e-37 0.33
CADH2_HUMAN CDH2 Cadherin-2 1.917e-37 0.30
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.493e-37 0.36
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 1.482e-36 0.67
KISSR_HUMAN KISS1R KiSS-1 receptor 1.576e-36 0.32
GRIA1_RAT Gria1 Glutamate receptor 1 1.035e-35 0.29
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.208e-35 0.31
MC5R_HUMAN MC5R Melanocortin receptor 5 1.658e-33 0.38
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.923e-33 0.35
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 4.56e-32 0.34
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 1.744e-31 0.67
MC3R_MOUSE Mc3r Melanocortin receptor 3 4.021e-31 0.36
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.154e-30 0.67
NK1R_CAVPO TACR1 Substance-P receptor 6.237e-30 0.35
NK3R_RAT Tacr3 Neuromedin-K receptor 7.23e-30 0.35
NK1R_RAT Tacr1 Substance-P receptor 1.174e-29 0.34
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.545e-29 0.36
NK1R_MOUSE Tacr1 Substance-P receptor 2.533e-29 0.29
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.776e-29 0.37
OXYR_RAT Oxtr Oxytocin receptor 3.429e-27 0.43
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 4.795e-27 0.34
FSHR_RAT Fshr Follicle-stimulating hormone receptor 1.792e-26 0.33
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 8.29e-25 0.33
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.307e-24 0.33
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 3.403e-24 0.36
CELA1_PIG CELA1 Chymotrypsin-like elastase family member 1 5.448e-24 0.29
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 5.478e-24 0.42
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.572e-23 0.38
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.136e-23 0.42
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 4.478e-23 0.40
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 5.889e-23 0.28
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1e-22 0.38
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 1.394e-22 0.38
V2R_RAT Avpr2 Vasopressin V2 receptor 4.448e-22 0.43
NK1R_HUMAN TACR1 Substance-P receptor 2.478e-21 0.46
V2R_HUMAN AVPR2 Vasopressin V2 receptor 3.356e-21 0.36
NEP_RABIT MME Neprilysin 2.395e-20 0.33
V1AR_RAT Avpr1a Vasopressin V1a receptor 3.302e-20 0.43
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.865e-20 0.40
ACE_RAT Ace Angiotensin-converting enzyme 3.424e-19 0.33
TYRO_HUMAN TYR Tyrosinase 4.573e-19 0.33
PSB5_YEAST PRE2 Proteasome subunit beta type-5 8.429e-19 0.30
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 1.039e-18 0.30
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 1.263e-18 0.39
OXYR_MOUSE Oxtr Oxytocin receptor 3.334e-18 0.29
ELAS_PSEAE lasB Elastase 6.555e-18 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 8.516e-18 0.35
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 9.837e-18 0.40
OPRK_RAT Oprk1 Kappa-type opioid receptor 3.327e-17 0.35
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.11e-16 0.56
EDNRA_HUMAN EDNRA Endothelin-1 receptor 9.992e-16 0.36
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 3.22e-15 0.33
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 7.661e-15 0.28
NMBR_HUMAN NMBR Neuromedin-B receptor 1.477e-14 0.31
ENV_HV1H2 env Envelope glycoprotein gp160 1.267e-13 0.30
GRIA1_HUMAN GRIA1 Glutamate receptor 1 2.185e-13 0.32
HDAC5_MOUSE Hdac5 Histone deacetylase 5 2.311e-13 0.29
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.462e-13 0.32
AGRA_STAAU agrA Accessory gene regulator protein A 2.77e-13 0.33
OPRM_MOUSE Oprm1 Mu-type opioid receptor 4.229e-13 0.38
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 7.762e-13 0.39
NRP1_RAT Nrp1 Neuropilin-1 1.064e-12 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.228e-12 0.40
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.287e-12 0.30
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 5.02e-12 0.34
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 3.382e-11 0.31
CHIB_SERMA chiB Chitinase B 1.458e-10 0.35
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.498e-10 0.45
V1BR_RAT Avpr1b Vasopressin V1b receptor 6.015e-10 0.33
TAT_HV1H2 tat Protein Tat 7.541e-10 0.29
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 8.956e-10 0.31
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.018e-09 0.34
RENI_RAT Ren1 Renin 2.432e-09 0.36
MMP8_RAT Mmp8 Neutrophil collagenase 4.226e-09 0.28
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 5.864e-09 0.30
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.088e-08 0.31
ITA3_HUMAN ITGA3 Integrin alpha-3 1.409e-08 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.55e-08 0.28
RENI_HUMAN REN Renin 1.697e-08 0.39
ITA5_HUMAN ITGA5 Integrin alpha-5 3.461e-08 0.33
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.126e-08 0.33
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 6.786e-08 0.32
ACE_HUMAN ACE Angiotensin-converting enzyme 9.311e-08 0.34
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.02e-07 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.1e-07 0.30
ECE1_RAT Ece1 Endothelin-converting enzyme 1 8.77e-07 0.28
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.009e-06 0.32
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 1.236e-06 0.31
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.385e-06 0.31
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 2.838e-06 0.34
CBPB2_HUMAN CPB2 Carboxypeptidase B2 2.904e-06 0.38
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 4.648e-06 0.34
HDAC6_MOUSE Hdac6 Histone deacetylase 6 7.488e-06 0.29
ITB6_HUMAN ITGB6 Integrin beta-6 7.783e-06 0.33
HDA11_HUMAN HDAC11 Histone deacetylase 11 8.157e-06 0.33
Q91H74_9FLAV Genome polyprotein 9.014e-06 0.31

Vamorolone

ATTY_RAT Tat Tyrosine aminotransferase 5.661e-105 0.39
GCR_RAT Nr3c1 Glucocorticoid receptor 1.835e-43 0.56
Q690N0_BOVIN PGR Progesterone receptor 1.102e-36 0.56
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.47e-30 0.40
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.528e-25 0.56
GCR_MOUSE Nr3c1 Glucocorticoid receptor 5.228e-17 0.40
NOS2_RAT Nos2 Nitric oxide synthase, inducible 7.316e-14 0.30
CP19A_HUMAN CYP19A1 Aromatase 4.78e-13 0.38
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.321e-12 0.40
GLNA_HUMAN GLUL Glutamine synthetase 1.321e-12 0.40
IL6_HUMAN IL6 Interleukin-6 4.698e-10 0.40
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.782e-09 0.33
CASP5_HUMAN CASP5 Caspase-5 3.119e-08 0.42
CASP4_HUMAN CASP4 Caspase-4 3.778e-07 0.42

Cefamandole_nafate

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 6.843e-103 0.78
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.204e-63 0.78
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.987e-56 0.78
B2ZTR6_ACIBA Beta-lactamase 6.849e-43 0.39
D6NSM8_ACIBA ampC Beta-lactamase 6.849e-43 0.39
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.205e-33 0.41
A2RP81_CITFR blaPER-2 Beta-lactamase 2.46e-26 0.31
CMA1_HUMAN CMA1 Chymase 4.722e-23 0.42
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.077e-22 0.41
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 5.788e-20 0.38
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 2.942e-13 0.46
BLAC_STAAU blaZ Beta-lactamase 2.999e-13 0.36
CATL1_RAT Ctsl Cathepsin L1 2.162e-10 0.32
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 6.367e-09 0.41
STRP_STRP1 ska Streptokinase A 7.322e-09 0.67
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 9.129e-09 0.35
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.94e-07 0.56
AMPC_PSEAE ampC Beta-lactamase 6.842e-06 0.32

Hydrocortisone_butyrate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.283e-101 0.67
Q690N0_BOVIN PGR Progesterone receptor 6.347e-69 0.43
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 5.103e-59 0.54
SHBG_HUMAN SHBG Sex hormone-binding globulin 9.438e-56 0.67
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.459e-44 0.37
CP19A_HUMAN CYP19A1 Aromatase 5.737e-44 0.41
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.215e-40 0.54
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 7.232e-38 0.31
GCR_HUMAN NR3C1 Glucocorticoid receptor 8.48e-38 0.67
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.499e-37 0.67
ATTY_RAT Tat Tyrosine aminotransferase 3.662e-32 0.30
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 4.821e-32 0.54
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.147e-27 0.37
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.257e-26 0.47
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.727e-25 0.49
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.825e-23 0.43
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 7.008e-23 0.37
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.353e-21 0.34
ANDR_RAT Ar Androgen receptor 2.706e-20 0.49
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.183e-18 0.54
GCR_RAT Nr3c1 Glucocorticoid receptor 3.702e-17 0.47
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.876e-14 0.36
GLNA_HUMAN GLUL Glutamine synthetase 1.876e-14 0.47
PRGR_RAT Pgr Progesterone receptor 2.975e-14 0.31
PRGR_RABIT PGR Progesterone receptor 1.582e-13 0.39
ANDR_MOUSE Ar Androgen receptor 3.04e-13 0.43
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.79e-13 0.54
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.67e-12 0.67
IL6_HUMAN IL6 Interleukin-6 1.655e-11 0.47
ERG2_YEAST ERG2 C-8 sterol isomerase 2.859e-10 0.41
ANDR_HUMAN AR Androgen receptor 1.092e-09 0.67
MCR_RAT Nr3c2 Mineralocorticoid receptor 3.069e-08 0.51
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.778e-07 0.60

Hydrocortisone_valerate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.541e-100 0.66
Q690N0_BOVIN PGR Progesterone receptor 3.711e-65 0.43
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.339e-58 0.53
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.351e-55 0.66
CP19A_HUMAN CYP19A1 Aromatase 7.122e-46 0.43
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.888e-40 0.53
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.134e-37 0.37
GCR_HUMAN NR3C1 Glucocorticoid receptor 5.658e-37 0.66
GCR_MOUSE Nr3c1 Glucocorticoid receptor 7.995e-37 0.66
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.315e-31 0.53
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.591e-25 0.46
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.15e-24 0.49
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.342e-23 0.37
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.879e-23 0.43
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.418e-22 0.36
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.329e-21 0.34
ANDR_RAT Ar Androgen receptor 4.028e-20 0.49
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 7.799e-20 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.111e-18 0.53
ATTY_RAT Tat Tyrosine aminotransferase 2.792e-17 0.32
GCR_RAT Nr3c1 Glucocorticoid receptor 3.765e-17 0.46
GLNA_HUMAN GLUL Glutamine synthetase 2.864e-14 0.46
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.32e-14 0.36
PRGR_RAT Pgr Progesterone receptor 4.43e-14 0.31
ANDR_MOUSE Ar Androgen receptor 3.129e-13 0.43
PRGR_RABIT PGR Progesterone receptor 3.363e-13 0.38
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.142e-13 0.53
MCR_HUMAN NR3C2 Mineralocorticoid receptor 5.27e-12 0.66
IL6_HUMAN IL6 Interleukin-6 2.312e-11 0.46
ANDR_HUMAN AR Androgen receptor 7.538e-11 0.66
ERG2_YEAST ERG2 C-8 sterol isomerase 2.216e-10 0.42
MCR_RAT Nr3c2 Mineralocorticoid receptor 3.892e-08 0.51
PRGR_HUMAN PGR Progesterone receptor 8.517e-08 0.46
PPO2_AGABI PPO2 Polyphenol oxidase 2 7.188e-07 0.59

Hydrocortisone_cypionate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.628e-97 0.76
Q690N0_BOVIN PGR Progesterone receptor 1.009e-54 0.46
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.756e-53 0.68
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.687e-51 0.47
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.417e-44 0.81
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.331e-37 0.47
GCR_HUMAN NR3C1 Glucocorticoid receptor 6.479e-37 0.68
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.308e-28 0.47
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.105e-25 0.48
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 2.609e-24 0.47
CP19A_HUMAN CYP19A1 Aromatase 1.174e-23 0.38
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 8.429e-23 0.36
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.427e-21 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 8.154e-21 0.39
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.064e-18 0.28
ANDR_RAT Ar Androgen receptor 9.421e-18 0.47
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.11e-16 0.47
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.996e-15 0.35
PRGR_RAT Pgr Progesterone receptor 5.329e-15 0.33
GLNA_HUMAN GLUL Glutamine synthetase 7.105e-15 0.48
PRGR_RABIT PGR Progesterone receptor 3.642e-14 0.37
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 6.661e-14 0.35
GCR_RAT Nr3c1 Glucocorticoid receptor 5.076e-12 0.48
ANDR_MOUSE Ar Androgen receptor 6.102e-12 0.39
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.64e-12 0.47
IL6_HUMAN IL6 Interleukin-6 7.762e-12 0.48
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.366e-11 0.35
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.166e-10 0.68
ERG2_YEAST ERG2 C-8 sterol isomerase 9.377e-10 0.38
ANDR_HUMAN AR Androgen receptor 1.438e-07 0.48
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.605e-07 0.57
MCR_RAT Nr3c2 Mineralocorticoid receptor 2.773e-07 0.45

Avacopan

A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 5.042e-97 0.32
RHOA_HUMAN RHOA Transforming protein RhoA 8.068e-62 0.33
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 3.047e-37 0.37
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.788e-30 0.39
ENV_HV1Y2 env Envelope glycoprotein gp160 2.902e-22 0.32
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 1.322e-21 0.30
SFRP1_HUMAN SFRP1 Secreted frizzled-related protein 1 5.691e-18 0.30
APOB_HUMAN APOB Apolipoprotein B-100 1.195e-17 0.30
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.11e-16 0.36
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 6.883e-15 0.31
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 1.879e-11 0.31
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 7.483e-11 0.29
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 9.093e-11 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.352e-10 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 2.764e-10 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 7.566e-10 0.35
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.236e-09 0.36
OX1R_HUMAN HCRTR1 Orexin receptor type 1 4.071e-09 0.36
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.317e-08 0.35
EED_HUMAN EED Polycomb protein EED 1.6e-07 0.30
RORB_HUMAN RORB Nuclear receptor ROR-beta 2.559e-07 0.30
OX2R_HUMAN HCRTR2 Orexin receptor type 2 3.843e-07 0.36
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 8.148e-07 0.29
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 9.999e-07 0.33
PRIO_MESAU PRNP Major prion protein 1.894e-06 0.29
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.957e-06 0.31
OX1R_RAT Hcrtr1 Orexin receptor type 1 2.718e-06 0.32
RORA_HUMAN RORA Nuclear receptor ROR-alpha 3.408e-06 0.30
CFAD_HUMAN CFD Complement factor D 9.818e-06 0.31

Cefiderocol

PBPA_PSEAE mrcA Penicillin-binding protein 1A 5.482e-96 0.43
Q83TT7_ECOLX ampC AmpC 2.512e-59 0.43
B2ZTR6_ACIBA Beta-lactamase 2.614e-56 0.49
D6NSM8_ACIBA ampC Beta-lactamase 2.614e-56 0.49
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 4.409e-54 0.49
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.073e-34 0.43
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.965e-33 0.49
Q3S5C3_SALNE sugE Efflux transporter 8.394e-27 0.43
Q48435_KLEPN bla LAT-2 Beta-lactamase 8.394e-27 0.43
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.087e-26 0.49
A2RP81_CITFR blaPER-2 Beta-lactamase 2.075e-19 0.43
AMPC_CITFR ampC Beta-lactamase 7.998e-13 0.31
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 8.396e-11 0.44
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 9.316e-10 0.45

Chloramphenicol_palmitate

P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 2.271e-95 0.33
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 8.003e-83 0.33
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 1.645e-73 0.37
TLR2_HUMAN TLR2 Toll-like receptor 2 1.076e-68 0.36
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 3.555e-63 0.33
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 9.171e-56 0.37
ACER2_HUMAN ACER2 Alkaline ceramidase 2 2.088e-47 0.38
NSMA_RAT Smpd2 Sphingomyelin phosphodiesterase 2 2.451e-47 0.32
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 6.03e-46 0.32
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 5.166e-42 0.33
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 1.096e-40 0.32
CERT_HUMAN CERT1 Ceramide transfer protein 1.474e-39 0.31
DPOLM_HUMAN POLM DNA-directed DNA/RNA polymerase mu 1.023e-37 0.30
PA2A1_NAJMO Acidic phospholipase A2 CM-I 1.023e-37 0.30
TDT_BOVIN DNTT DNA nucleotidylexotransferase 1.023e-37 0.30
NSMA_HUMAN SMPD2 Sphingomyelin phosphodiesterase 2 2.041e-30 0.38
POLI_MOUSE Poli DNA polymerase iota 2.826e-24 0.30
GLO2_RAT Hagh Hydroxyacylglutathione hydrolase, mitochondrial 8.089e-24 0.29
PPM1A_HUMAN PPM1A Protein phosphatase 1A 2.063e-23 0.29
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 1.141e-21 0.37
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 5.403e-20 0.33
KPCL_MOUSE Prkch Protein kinase C eta type 6.95e-19 0.36
POLH_HUMAN POLH DNA polymerase eta 9.992e-16 0.30
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 6.306e-14 0.33
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.875e-13 0.35
CEGT_HUMAN UGCG Ceramide glucosyltransferase 3.71e-13 0.38
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 5.834e-13 0.37
POLK_HUMAN POLK DNA polymerase kappa 3.144e-12 0.30
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 2.214e-11 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.783e-11 0.30
KPCA_BOVIN PRKCA Protein kinase C alpha type 5.597e-11 0.36
MEP2_YEAST MEP2 Ammonium transporter MEP2 1.068e-10 0.31
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 1.847e-10 0.37
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 4.884e-10 0.29
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 2.027e-09 0.33
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.241e-08 0.32
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 1.464e-08 0.30
DPOLL_HUMAN POLL DNA polymerase lambda 1.867e-08 0.30
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 5.549e-08 0.30
ASAH1_HUMAN ASAH1 Acid ceramidase 8.662e-08 0.61
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 9.002e-08 0.29
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 1.39e-07 0.28
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 1.582e-07 0.31
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.806e-07 0.30
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 6.964e-07 0.31
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 8.637e-07 0.31
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 9.396e-07 0.29
COLA_CLOPE colA Collagenase ColA 1.681e-06 0.29
KPCA_MOUSE Prkca Protein kinase C alpha type 1.983e-06 0.40
MGLL_MOUSE Mgll Monoglyceride lipase 2.445e-06 0.35
DPOLB_RAT Polb DNA polymerase beta 2.653e-06 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.099e-06 0.36

Ceftobiprole_medocaril

Q7DHH4_STAAU mecA MecA 5.399e-87 0.70
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 3.899e-38 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.198e-23 0.35
B2ZTR6_ACIBA Beta-lactamase 3.807e-22 0.35
D6NSM8_ACIBA ampC Beta-lactamase 3.807e-22 0.35
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.509e-19 0.35
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.246e-10 0.42
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 9.755e-08 0.35

Drostanolone_propionate

G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 8.41e-84 0.36
TAT_HV112 tat Protein Tat 7.724e-60 0.39
ANDR_RAT Ar Androgen receptor 5.589e-51 0.53
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.939e-49 0.34
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.469e-44 0.34
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.942e-39 0.41
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.545e-36 0.41
SHBG_RAT Shbg Sex hormone-binding globulin 9.108e-33 0.41
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.021e-29 0.34
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 5.245e-27 0.33
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 7.397e-22 0.29
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.464e-21 0.34
NMDE3_HUMAN GRIN2C Glutamate receptor ionotropic, NMDA 2C 3.27e-21 0.34
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.357e-20 0.32
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 5.176e-20 0.31
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.829e-19 0.30
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.211e-18 0.30
NMDE4_HUMAN GRIN2D Glutamate receptor ionotropic, NMDA 2D 1.045e-17 0.34
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 2.22e-16 0.31
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.776e-15 0.35
ANDR_MOUSE Ar Androgen receptor 5.773e-15 0.53
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.831e-14 0.30
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 7.017e-14 0.34
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 7.128e-14 0.41
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 7.572e-14 0.34
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 8.726e-14 0.33
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.665e-13 0.34
REST_BORBU resT Telomere resolvase ResT 5.245e-13 0.32
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.506e-12 0.33
Q690N0_BOVIN PGR Progesterone receptor 1.085e-11 0.41
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 1.437e-11 0.28
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 7.782e-11 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.72e-09 0.29
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 5.304e-09 0.34
LICH_HUMAN LIPA Lysosomal acid lipase/cholesteryl ester hydrolase 1.846e-08 0.30
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.881e-08 0.33
ECR_DROME EcR Ecdysone receptor 2.543e-08 0.29
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 6.612e-08 0.33
ERG2_YEAST ERG2 C-8 sterol isomerase 1.345e-07 0.29
PRGR_RABIT PGR Progesterone receptor 1.76e-07 0.41
MCR_RAT Nr3c2 Mineralocorticoid receptor 1.143e-06 0.41
DPOLB_RAT Polb DNA polymerase beta 1.347e-06 0.31
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 2.091e-06 0.35
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.369e-06 0.29

Prednisolone_tebutate

ATTY_RAT Tat Tyrosine aminotransferase 4.649e-83 0.32
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 7.097e-70 0.73
GCR_MOUSE Nr3c1 Glucocorticoid receptor 4.617e-44 0.73
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.234e-43 0.73
Q690N0_BOVIN PGR Progesterone receptor 2.349e-41 0.45
GCR_RAT Nr3c1 Glucocorticoid receptor 2.322e-37 0.73
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.586e-26 0.51
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.38e-22 0.73
GLNA_HUMAN GLUL Glutamine synthetase 4.38e-22 0.73
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.111e-20 0.33
IL6_HUMAN IL6 Interleukin-6 1.651e-17 0.73
CP19A_HUMAN CYP19A1 Aromatase 2.22e-16 0.43
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.886e-15 0.33
PRGR_RAT Pgr Progesterone receptor 2.975e-14 0.31
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.372e-13 0.30
PRGR_RABIT PGR Progesterone receptor 1.048e-09 0.31
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 9.513e-09 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.929e-08 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.943e-07 0.33
ANDR_RAT Ar Androgen receptor 7.137e-07 0.45
PPO2_AGABI PPO2 Polyphenol oxidase 2 7.653e-07 0.45

Hydrocortisone_probutate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.166e-82 0.61
Q690N0_BOVIN PGR Progesterone receptor 4.54e-58 0.41
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.687e-51 0.47
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.366e-47 0.56
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.061e-37 0.47
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.152e-35 0.64
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.122e-31 0.56
CP19A_HUMAN CYP19A1 Aromatase 2.845e-29 0.38
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.308e-28 0.47
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 4.937e-24 0.47
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.725e-23 0.39
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.049e-21 0.35
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.071e-21 0.35
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.427e-21 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.695e-21 0.45
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3.494e-19 0.30
ANDR_RAT Ar Androgen receptor 1.217e-18 0.47
GCR_RAT Nr3c1 Glucocorticoid receptor 1.78e-18 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.11e-16 0.47
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.465e-14 0.35
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.841e-14 0.36
PRGR_RAT Pgr Progesterone receptor 1.372e-13 0.30
PRGR_RABIT PGR Progesterone receptor 3.383e-13 0.37
ANDR_MOUSE Ar Androgen receptor 9.583e-13 0.45
GLNA_HUMAN GLUL Glutamine synthetase 3.708e-12 0.39
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.64e-12 0.47
MCR_HUMAN NR3C2 Mineralocorticoid receptor 6.67e-10 0.56
ERG2_YEAST ERG2 C-8 sterol isomerase 9.377e-10 0.38
IL6_HUMAN IL6 Interleukin-6 1.058e-09 0.39
MCR_RAT Nr3c2 Mineralocorticoid receptor 2.773e-07 0.45
ANDR_HUMAN AR Androgen receptor 4.102e-07 0.58
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.335e-06 0.57

Prednisolone_phosphate

ATTY_RAT Tat Tyrosine aminotransferase 9.609e-82 0.31
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.101e-75 0.75
Q690N0_BOVIN PGR Progesterone receptor 2.11e-48 0.46
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.4e-45 0.75
GCR_MOUSE Nr3c1 Glucocorticoid receptor 7.717e-43 0.75
GCR_RAT Nr3c1 Glucocorticoid receptor 5.962e-35 0.75
SHBG_HUMAN SHBG Sex hormone-binding globulin 4.575e-33 0.52
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 8.541e-23 0.75
GLNA_HUMAN GLUL Glutamine synthetase 8.541e-23 0.75
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.735e-22 0.34
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.654e-21 0.33
CP19A_HUMAN CYP19A1 Aromatase 1.659e-20 0.47
IL6_HUMAN IL6 Interleukin-6 4.566e-18 0.75
NOS2_RAT Nos2 Nitric oxide synthase, inducible 6.517e-14 0.30
PRGR_RAT Pgr Progesterone receptor 7.316e-14 0.30
PRGR_RABIT PGR Progesterone receptor 1.311e-09 0.32
ANDR_RAT Ar Androgen receptor 1.634e-09 0.46
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.881e-08 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.409e-07 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.027e-07 0.46
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 9.272e-07 0.33

Racephedrine

GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 4.734e-79 0.36
ACER2_HUMAN ACER2 Alkaline ceramidase 2 7.865e-58 0.46
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.067e-46 0.36
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.651e-34 0.37
BLAB_BACCE Metallo-beta-lactamase type 2 1.643e-33 0.38
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.874e-33 0.39
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 2.026e-28 0.35
ACE_MOUSE Ace Angiotensin-converting enzyme 6.284e-27 0.31
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.034e-26 0.37
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.427e-23 0.48
NSMA_HUMAN SMPD2 Sphingomyelin phosphodiesterase 2 4.633e-23 0.28
MANR_PSEPU mdlA Mandelate racemase 3.381e-22 0.35
EST1_RABIT Liver carboxylesterase 1 6.989e-22 0.32
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 6.586e-18 0.29
G3HDX1_CRIGR Alpha-1B adrenergic receptor 5.295e-17 0.32
MA2A1_HUMAN MAN2A1 Alpha-mannosidase 2 1.11e-16 0.32
MA1B1_HUMAN MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 3.331e-16 0.32
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.332e-15 0.39
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 7.994e-15 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.652e-14 0.33
CALM_BOVIN CALM Calmodulin 5.228e-13 0.35
EST2_HUMAN CES2 Cocaine esterase 6.251e-13 0.39
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 1.508e-11 0.28
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.436e-10 0.44
PPO1_AGABI PPO1 Polyphenol oxidase 1 1.441e-10 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.532e-10 0.39
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.779e-10 0.47
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 5.982e-10 0.29
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 7.2e-10 0.31
BLAB_AERHY cphA Metallo-beta-lactamase type 2 1.645e-09 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.614e-09 0.35
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 2.734e-09 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.598e-09 0.29
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.084e-08 0.43
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.964e-08 0.47
EST1_HUMAN CES1 Liver carboxylesterase 1 2.377e-08 0.39
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.189e-08 0.29
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.301e-08 0.29
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 4.433e-08 0.68
NK1R_RAT Tacr1 Substance-P receptor 5.388e-08 0.29
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.468e-07 0.38
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 3.614e-07 0.56
Q9WTR4_RAT Slc6a2 Transporter 5.476e-07 0.47
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 5.775e-07 0.34
SCYD_MAGO7 SDH1 Scytalone dehydratase 7.535e-07 0.31
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.834e-07 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.071e-06 0.30
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.085e-06 0.50
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.864e-06 0.32
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.003e-06 0.33
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 4.107e-06 0.28
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.553e-06 0.39
OXDA_MOUSE Dao D-amino-acid oxidase 5.379e-06 0.28

Loteprednol

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.665e-78 0.73
ATTY_RAT Tat Tyrosine aminotransferase 2.324e-64 0.30
Q690N0_BOVIN PGR Progesterone receptor 4.013e-60 0.48
GCR_RAT Nr3c1 Glucocorticoid receptor 1.81e-47 0.73
GCR_HUMAN NR3C1 Glucocorticoid receptor 4.443e-43 0.73
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.168e-42 0.73
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 4.009e-39 0.35
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.181e-37 0.50
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.122e-31 0.73
CP19A_HUMAN CYP19A1 Aromatase 1.533e-27 0.44
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.151e-22 0.35
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.311e-22 0.35
GLNA_HUMAN GLUL Glutamine synthetase 3.575e-22 0.73
IL6_HUMAN IL6 Interleukin-6 1.407e-17 0.73
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.998e-15 0.36
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.987e-14 0.32
PRGR_RAT Pgr Progesterone receptor 2.132e-14 0.32
PRGR_RABIT PGR Progesterone receptor 2.742e-13 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.744e-13 0.35
ANDR_RAT Ar Androgen receptor 1.446e-12 0.48
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.41e-09 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 6.955e-08 0.30
ANDR_MOUSE Ar Androgen receptor 1.425e-07 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.556e-07 0.48
TAT_HV112 tat Protein Tat 1.03e-06 0.30
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.781e-06 0.73

Dordaviprone

BRS3_RAT Brs3 Bombesin receptor subtype-3 2.496e-78 0.35
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 2.18e-21 0.35
NOX5_HUMAN NOX5 NADPH oxidase 5 3.416e-18 0.30
ACES_MOUSE Ache Acetylcholinesterase 1.11e-16 0.32
CY24B_HUMAN CYBB Cytochrome b-245 heavy chain 4.885e-15 0.30
BLAN_ENTCL nmcA Imipenem-hydrolyzing beta-lactamase 1.033e-14 0.30
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 4.617e-11 0.32
ACES_ANOGA Ace Acetylcholinesterase 4.62e-09 0.32
BLAB_BACFG ccrA Metallo-beta-lactamase type 2 1.368e-08 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.805e-08 0.32
AMYP_PIG AMY2 Pancreatic alpha-amylase 5.06e-07 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 6.792e-07 0.30
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 9.521e-07 0.32
ACES_ELEEL ache Acetylcholinesterase 1.029e-06 0.36
NOX1_HUMAN NOX1 NADPH oxidase 1 1.46e-06 0.30
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 7.174e-06 0.32

Chromium_nicotinate

THAS_HUMAN TBXAS1 Thromboxane-A synthase 2.029e-74 0.44
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.111e-61 0.49
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 1.512e-50 0.41
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.007e-41 0.47
D3ZDM7_RAT Ddo D-aspartate oxidase 3.875e-36 0.29
OXDD_MOUSE Ddo D-aspartate oxidase 3.875e-36 0.29
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 3.875e-36 0.29
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 5.412e-32 0.32
EST1_RABIT Liver carboxylesterase 1 1.523e-28 0.33
TA2R_RAT Tbxa2r Thromboxane A2 receptor 3.205e-23 0.40
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.954e-22 0.40
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 3.937e-22 0.45
KLK14_HUMAN KLK14 Kallikrein-14 1.193e-19 0.31
FA12_HUMAN F12 Coagulation factor XII 8.258e-19 0.36
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 2.882e-18 0.40
OXDD_HUMAN DDO D-aspartate oxidase 4.879e-18 0.29
CP2B6_HUMAN CYP2B6 Cytochrome P450 2B6 8.104e-18 0.28
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 8.104e-18 0.28
PPO1_AGABI PPO1 Polyphenol oxidase 1 9.273e-18 0.29
PA_I000X PA Polymerase acidic protein 1.882e-17 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.955e-17 0.42
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 4.441e-16 0.40
EST2_HUMAN CES2 Cocaine esterase 1.11e-15 0.33
ISPH_AQUAE ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1.443e-15 0.30
CYSP_PLAFA Trophozoite cysteine proteinase 1.261e-13 0.40
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 1.781e-13 0.49
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 2.726e-13 0.38
KLK5_HUMAN KLK5 Kallikrein-5 7.666e-13 0.31
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 8.432e-13 0.35
CP19A_RAT Cyp19a1 Aromatase 9.438e-13 0.32
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 1.272e-12 0.49
LDLR_HUMAN LDLR Low-density lipoprotein receptor 4.323e-12 0.29
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.384e-11 0.35
O96526_LEIMA CRK3 Cdc2-related kinase 2.659e-10 0.30
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.866e-10 0.37
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 3.238e-10 0.30
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.131e-10 0.49
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 2.44e-09 0.31
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.63e-09 0.41
EST1_HUMAN CES1 Liver carboxylesterase 1 3.275e-09 0.33
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 1.322e-08 0.29
KLK7_HUMAN KLK7 Kallikrein-7 1.522e-08 0.31
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.849e-08 0.35
AOC3_BOVIN AOC3 Membrane primary amine oxidase 1.914e-08 0.32
POLG_HCV77 Genome polyprotein 2.702e-08 0.35
PA_I34A1 PA Polymerase acidic protein 4.898e-08 0.33
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 5.335e-08 0.39
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 5.773e-08 0.33
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 7.261e-08 0.36
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 7.762e-08 0.29
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.473e-07 0.35
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 1.986e-07 0.30
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 2.68e-07 0.28
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 4.587e-07 0.31
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.047e-07 0.31
HDAC1_HUMAN HDAC1 Histone deacetylase 1 6.221e-07 0.45
MIP_LEGPN mip Outer membrane protein MIP 8.358e-07 0.29
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 9.875e-07 0.33
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.669e-06 0.29
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.689e-06 0.30
A9XFY4_MUSDO nAChRalpha5 Nicotinic acetylcholine receptor alpha 5 subunit 4.241e-06 0.29
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 7.099e-06 0.49
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 7.928e-06 0.42

Imetelstat

KTHY_HUMAN DTYMK Thymidylate kinase 1.863e-72 0.43
SNAT_SHEEP AANAT Serotonin N-acetyltransferase 3.876e-69 0.32
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 1.473e-60 0.38
RASK_HUMAN KRAS GTPase KRas 2.252e-56 0.32
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 1.886e-55 0.36
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 1.886e-55 0.36
FUT6_HUMAN FUT6 Alpha-(1,3)-fucosyltransferase 6 5.813e-53 0.31
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 1.603e-47 0.30
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 9.246e-45 0.37
C3SIU2_ECOLX metJ Met repressor 2.214e-43 0.31
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 5.672e-43 0.30
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 1.233e-42 0.31
DPOD1_HUMAN POLD1 DNA polymerase delta catalytic subunit 3.458e-38 0.30
HGPRT_MYCTU hpt Hypoxanthine-guanine phosphoribosyltransferase 8.523e-37 0.29
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 1.644e-36 0.29
D3ZGQ2_RAT Tk2 Thymidine kinase 2 1.034e-35 0.28
DPOLB_HUMAN POLB DNA polymerase beta 5.542e-34 0.37
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 6.139e-31 0.30
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 5.521e-30 0.42
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.924e-29 0.33
NMT_YEAST NMT1 Glycylpeptide N-tetradecanoyltransferase 3.851e-29 0.36
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 2.628e-25 0.34
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 1.106e-24 0.30
Q3ZDS5_9HEPC NS5B 1.248e-24 0.30
KITH_RAT Tk1 Thymidine kinase, cytosolic 8.315e-23 0.36
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 2.067e-21 0.31
BPL1_HUMAN HLCS Biotin--protein ligase 5.128e-21 0.30
DPOL_HHV1K DNA polymerase catalytic subunit 4.884e-19 0.30
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 9.258e-19 0.30
SYI_ECOLI ileS Isoleucine--tRNA ligase 1.033e-17 0.28
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 1.11e-16 0.38
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 1.11e-16 0.32
Q9HX69_PSEAE rocR RocR 9.992e-16 0.30
KTHY_MYCTU tmk Thymidylate kinase 2.665e-15 0.33
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 5.662e-15 0.28
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 7.105e-15 0.32
DPOL_HHV11 DNA polymerase catalytic subunit 7.55e-14 0.30
DPOL_VZVD DNA polymerase catalytic subunit 7.55e-14 0.30
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.565e-13 0.29
TYSY_LACCA thyA Thymidylate synthase 2.338e-13 0.32
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 2.908e-13 0.29
DNK_DROME dnk Deoxynucleoside kinase 8.357e-13 0.29
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.043e-11 0.28
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 1.063e-11 0.28
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.17e-11 0.30
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.327e-10 0.31
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 5.515e-10 0.31
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 7.2e-10 0.31
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 1.863e-08 0.32
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 4.668e-08 0.32
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 6.944e-08 0.28
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.219e-07 0.29
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 2.469e-07 0.31
5NTD_HUMAN NT5E 5'-nucleotidase 2.845e-06 0.30
ADCY5_RAT Adcy5 Adenylate cyclase type 5 2.999e-06 0.30
CLAT_HUMAN CHAT Choline O-acetyltransferase 4.1e-06 0.32
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 4.427e-06 0.34
P2RX1_RAT P2rx1 P2X purinoceptor 1 7.169e-06 0.31

Sodium_phosphate_dibasic

B1LRJ1_ECOSM traI Type IV secretion-like conjugative transfer relaxase protein TraI 4.734e-71 0.40
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 9.7e-12 0.29

Prednisone_acetate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 7.503e-70 0.54
Q690N0_BOVIN PGR Progesterone receptor 9.99e-58 0.39
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.093e-34 0.54
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.613e-31 0.51
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.387e-30 0.78
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 8.455e-26 0.54
GCR_RAT Nr3c1 Glucocorticoid receptor 4.86e-23 0.54
CP19A_HUMAN CYP19A1 Aromatase 2.868e-21 0.46
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 2.139e-18 0.29
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 4.879e-18 0.29
GLNA_HUMAN GLUL Glutamine synthetase 1.11e-16 0.54
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.266e-14 0.32
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.581e-13 0.29
PRGR_RAT Pgr Progesterone receptor 1.842e-13 0.29
PRGR_RABIT PGR Progesterone receptor 2.719e-13 0.32
IL6_HUMAN IL6 Interleukin-6 3.694e-13 0.54
ANDR_RAT Ar Androgen receptor 5.229e-12 0.39
ATTY_RAT Tat Tyrosine aminotransferase 7.48e-09 0.29
ANDR_MOUSE Ar Androgen receptor 1.383e-07 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 7.696e-07 0.32
PPO2_AGABI PPO2 Polyphenol oxidase 2 9.369e-07 0.50
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.064e-06 0.29

Gestonorone_caproate

Q690N0_BOVIN PGR Progesterone receptor 1.055e-66 0.56
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.755e-44 0.38
PRGR_RAT Pgr Progesterone receptor 2.943e-37 0.55
SHBG_HUMAN SHBG Sex hormone-binding globulin 8.189e-35 0.52
F1Q298_CANLF NR3C1 Glucocorticoid receptor 5.245e-27 0.33
GCR_PIG NR3C1 Glucocorticoid receptor 5.245e-27 0.33
GCR_MOUSE Nr3c1 Glucocorticoid receptor 4.913e-25 0.32
PRGR_RABIT PGR Progesterone receptor 7.719e-24 0.54
ANDR_RAT Ar Androgen receptor 1.445e-22 0.56
PRGR_HUMAN PGR Progesterone receptor 1.028e-21 0.52
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.372e-18 0.29
ANDR_HUMAN AR Androgen receptor 1.41e-18 0.51
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.131e-18 0.31
DHB7_HUMAN HSD17B7 3-keto-steroid reductase 1.006e-17 0.28
CP19A_HUMAN CYP19A1 Aromatase 7.772e-16 0.46
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.221e-14 0.31
ANDR_MOUSE Ar Androgen receptor 2.175e-11 0.44
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.647e-10 0.56
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 1.072e-09 0.28
STS_HUMAN STS Steryl-sulfatase 2.617e-09 0.32
GLNA_HUMAN GLUL Glutamine synthetase 5.122e-09 0.28
MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.229e-08 0.51
ERG2_YEAST ERG2 C-8 sterol isomerase 5.137e-08 0.31
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.22e-07 0.30
IL6_HUMAN IL6 Interleukin-6 3.118e-07 0.28
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.119e-06 0.31
GCR_RAT Nr3c1 Glucocorticoid receptor 1.152e-06 0.33
LSS_RAT Lss Lanosterol synthase 3.601e-06 0.29
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.336e-06 0.36
PPO2_AGABI PPO2 Polyphenol oxidase 2 8.625e-06 0.36

Segesterone_acetate

Q690N0_BOVIN PGR Progesterone receptor 1.211e-65 0.62
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.661e-53 0.38
PRGR_RAT Pgr Progesterone receptor 1.672e-50 0.56
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.729e-42 0.52
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.989e-37 0.31
F1Q298_CANLF NR3C1 Glucocorticoid receptor 1.737e-25 0.31
GCR_PIG NR3C1 Glucocorticoid receptor 1.737e-25 0.31
PRGR_RABIT PGR Progesterone receptor 5.273e-25 0.55
SHBG_RAT Shbg Sex hormone-binding globulin 5.889e-23 0.28
ANDR_RAT Ar Androgen receptor 1.649e-22 0.62
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.195e-22 0.34
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 6.524e-20 0.29
PRGR_HUMAN PGR Progesterone receptor 5.551e-16 0.52
ANDR_HUMAN AR Androgen receptor 8.882e-16 0.52
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 5.72e-13 0.34
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.792e-12 0.52
ANDR_MOUSE Ar Androgen receptor 8.216e-11 0.38
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.027e-10 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.035e-10 0.34
GCR_MOUSE Nr3c1 Glucocorticoid receptor 4.506e-10 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.999e-09 0.34
ERG2_YEAST ERG2 C-8 sterol isomerase 2.612e-08 0.34
CP19A_HUMAN CYP19A1 Aromatase 3.007e-08 0.52
GCR_HUMAN NR3C1 Glucocorticoid receptor 4.089e-07 0.62

Paramethasone_acetate

ATTY_RAT Tat Tyrosine aminotransferase 1.181e-64 0.30
Q690N0_BOVIN PGR Progesterone receptor 3.585e-41 0.55
GCR_RAT Nr3c1 Glucocorticoid receptor 3.552e-39 0.42
GCR_HUMAN NR3C1 Glucocorticoid receptor 5.191e-32 0.55
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.11e-16 0.38
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.323e-12 0.39
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.732e-12 0.38
GLNA_HUMAN GLUL Glutamine synthetase 7.732e-12 0.38
IL6_HUMAN IL6 Interleukin-6 1.886e-09 0.38

Eslicarbazepine

TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 1.304e-60 0.33
AMPX_VIBPR Bacterial leucyl aminopeptidase 2.786e-28 0.40
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 8.534e-26 0.41
ACE_RABIT ACE Angiotensin-converting enzyme 2.292e-22 0.38
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 4.078e-22 0.41
PPCE_MOUSE Prep Prolyl endopeptidase 1.453e-20 0.29
Q8IM16_PLAF7 Plasmepsin IV 9.771e-18 0.28
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.541e-17 0.30
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.554e-15 0.32
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 1.492e-13 0.30
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.025e-13 0.41
ACE_RAT Ace Angiotensin-converting enzyme 3.983e-12 0.42
Q6RY99_RAT Tetraspanin 1.309e-11 0.31
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.433e-10 0.33
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.303e-09 0.34
PGH1_RABIT PTGS1 Prostaglandin G/H synthase 1 1.543e-09 0.30
PGH2_RABIT PTGS2 Prostaglandin G/H synthase 2 5.995e-09 0.30
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 8.515e-09 0.29
VACHT_TETCF Vesicular acetylcholine transporter 2.272e-08 0.31
DEF_STAAM def Peptide deformylase 9.551e-08 0.31
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 2.764e-07 0.30
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 3.209e-06 0.33
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 3.32e-06 0.33
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 3.377e-06 0.33
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 4.01e-06 0.29
NOTUM_MOUSE Notum Palmitoleoyl-protein carboxylesterase NOTUM 6.028e-06 0.31

Daridorexant

OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.651e-53 0.44
OX1R_HUMAN HCRTR1 Orexin receptor type 1 3.091e-50 0.44
OX1R_MOUSE Hcrtr1 Orexin receptor type 1 1.777e-24 0.30
OX2R_MOUSE Hcrtr2 Orexin receptor type 2 1.777e-24 0.30
OX1R_RAT Hcrtr1 Orexin receptor type 1 5.697e-18 0.38
OX2R_RAT Hcrtr2 Orexin receptor type 2 7.216e-15 0.42
HSC82_YEAST HSC82 ATP-dependent molecular chaperone HSC82 2.637e-08 0.29
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 1.698e-06 0.31
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.764e-06 0.29
NOX5_HUMAN NOX5 NADPH oxidase 5 2.849e-06 0.29
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 8.14e-06 0.31

Deutivacaftor

CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 2.567e-51 0.85
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 1.329e-37 0.30
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 3.299e-36 0.29
BGLR_HUMAN GUSB Beta-glucuronidase 1.615e-32 0.33
NMBR_HUMAN NMBR Neuromedin-B receptor 1.06e-28 0.32
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.519e-26 0.32
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 4.705e-26 0.32
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.836e-24 0.32
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 4.216e-24 0.32
NMBR_RAT Nmbr Neuromedin-B receptor 7.007e-24 0.29
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 2.466e-21 0.32
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 3.625e-19 0.32
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 5.684e-19 0.29
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 6.791e-19 0.32
AAKB2_HUMAN PRKAB2 5'-AMP-activated protein kinase subunit beta-2 3.615e-18 0.29
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 5.729e-18 0.39
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 1.006e-17 0.28
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.11e-16 0.30
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 5.107e-15 0.30
DPOL_HHV11 DNA polymerase catalytic subunit 4.907e-14 0.31
DPOL_VZVD DNA polymerase catalytic subunit 4.907e-14 0.31
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 1.581e-13 0.29
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 9.921e-13 0.31
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 3.845e-11 0.29
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 2.417e-10 0.29
KI20A_HUMAN KIF20A Kinesin-like protein KIF20A 1.012e-09 0.28
MMP8_RAT Mmp8 Neutrophil collagenase 1.147e-09 0.30
MTSI_SPISQ sssIM CPG DNA methylase 3.598e-09 0.29
ELAS_PSEAE lasB Elastase 5.216e-09 0.30
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 1.176e-08 0.36
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.185e-08 0.32
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 1.452e-07 0.29
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.92e-07 0.39
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 5.458e-07 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 6.149e-07 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 6.33e-07 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.897e-07 0.29
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.383e-07 0.29
ECE1_RAT Ece1 Endothelin-converting enzyme 1 7.416e-07 0.29
AA1R_BOVIN ADORA1 Adenosine receptor A1 1.026e-06 0.31
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 2.08e-06 0.39
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 3.101e-06 0.29
MMP8_HUMAN MMP8 Neutrophil collagenase 3.436e-06 0.30
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 4.865e-06 0.29
NEP_RABIT MME Neprilysin 6.982e-06 0.29

Chlorphenesin_carbamate

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.301e-51 0.46
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.049e-39 0.35
D3W065_CHRVL cviR CviR transcriptional regulator 5.06e-39 0.31
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 5.351e-37 0.29
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.154e-30 0.44
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.155e-29 0.46
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.2e-25 0.40
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 2.248e-24 0.41
ACRO_PIG ACR Acrosin 1.004e-23 0.40
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 2.196e-23 0.30
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 4.757e-23 0.30
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.739e-22 0.28
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.242e-20 0.41
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.179e-20 0.36
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 4.399e-20 0.32
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.345e-20 0.46
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 8.108e-18 0.30
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.326e-17 0.41
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 5.551e-16 0.30
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.887e-15 0.36
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 2.887e-15 0.29
FTSZ_STAAU ftsZ Cell division protein FtsZ 5.884e-15 0.28
PTPRE_HUMAN PTPRE Receptor-type tyrosine-protein phosphatase epsilon 7.438e-15 0.28
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 4.086e-14 0.31
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 6.761e-14 0.31
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 2.415e-13 0.33
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 3.055e-13 0.45
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.022e-12 0.44
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 5.179e-12 0.29
DYR_MYCTU folA Dihydrofolate reductase 7.71e-12 0.32
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.217e-11 0.40
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.92e-11 0.31
ACRO_HUMAN ACR Acrosin 1.166e-10 0.39
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 1.511e-10 0.31
S100B_HUMAN S100B Protein S100-B 4.535e-10 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 6.017e-10 0.31
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 7.236e-10 0.33
EST1_RABIT Liver carboxylesterase 1 8.117e-10 0.32
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.138e-09 0.48
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.247e-09 0.29
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.613e-09 0.38
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 5.284e-09 0.32
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 6.293e-09 0.37
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 7.191e-09 0.32
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 7.204e-09 0.48
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 1.709e-08 0.29
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 2.353e-08 0.32
KLK_PIG Glandular kallikrein 3.22e-08 0.33
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 6.47e-08 0.33
TAU_HUMAN MAPT Microtubule-associated protein tau 7.752e-08 0.33
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 8.47e-08 0.35
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 9.144e-08 0.29
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 1.199e-07 0.28
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.502e-07 0.31
CCNC_HUMAN CCNC Cyclin-C 2.811e-07 0.34
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 3.771e-07 0.29
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 4.668e-07 0.36
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 6.322e-07 0.28
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 7.274e-07 0.33
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 8.292e-07 0.33
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 9.903e-07 0.29
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 1.057e-06 0.41
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 1.362e-06 0.33
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 1.949e-06 0.31
GP183_MOUSE Gpr183 G-protein coupled receptor 183 2.798e-06 0.34
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 3.043e-06 0.48
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 3.301e-06 0.40
MEP50_HUMAN WDR77 Methylosome protein 50 8.679e-06 0.33
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 8.925e-06 0.39
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 9.971e-06 0.33

Chromium_gluconate

Q9GRG6_9TRYP 6pgl 6-phosphogluconolactonase 3.453e-43 0.34
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 3.875e-36 0.29
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 7.518e-07 0.29

Methylprednisolone_hemisuccinate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.017e-40 0.51
AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 1.557e-37 0.30
Q690N0_BOVIN PGR Progesterone receptor 1.067e-34 0.42
GCR_MOUSE Nr3c1 Glucocorticoid receptor 5.123e-32 0.60
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.091e-26 0.72
GCR_RAT Nr3c1 Glucocorticoid receptor 1.037e-24 0.51
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 3.69e-24 0.30
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.221e-15 0.51
GLNA_HUMAN GLUL Glutamine synthetase 1.221e-15 0.51
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.581e-13 0.39
IL6_HUMAN IL6 Interleukin-6 1.864e-12 0.51
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 3.581e-12 0.30
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 4.487e-11 0.30
CP19A_HUMAN CYP19A1 Aromatase 9.08e-09 0.40
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 6.746e-06 0.30
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 6.746e-06 0.30

Edetate_disodium_anhydrous

CAH4_BOVIN CA4 Carbonic anhydrase 4 4.887e-37 0.41
CAH4_HUMAN CA4 Carbonic anhydrase 4 9.702e-24 0.40
PURA2_HUMAN ADSS2 Adenylosuccinate synthetase isozyme 2 3.462e-20 0.32
CAH1_HUMAN CA1 Carbonic anhydrase 1 6.328e-15 0.41
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.221e-13 0.41
MVD1_HUMAN MVD Diphosphomevalonate decarboxylase 1.339e-11 0.28
AROA_ECOLI aroA 3-phosphoshikimate 1-carboxyvinyltransferase 4.441e-11 0.33

Methylprednisolone_aceponate

AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 1.264e-35 0.28
Q690N0_BOVIN PGR Progesterone receptor 2.736e-33 0.40
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.314e-23 0.41
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 6.037e-23 0.28
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.368e-22 0.41
GCR_RAT Nr3c1 Glucocorticoid receptor 1.74e-19 0.41
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.772e-16 0.59
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.132e-12 0.41
GLNA_HUMAN GLUL Glutamine synthetase 1.132e-12 0.41
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 1.399e-11 0.28
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 1.539e-10 0.28
IL6_HUMAN IL6 Interleukin-6 4.161e-10 0.41
CP19A_HUMAN CYP19A1 Aromatase 1.184e-08 0.40
ATTY_RAT Tat Tyrosine aminotransferase 1.585e-08 0.28
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.806e-07 0.39

Diloxanide_furoate

POLG_HRV16 Genome polyprotein 1.888e-35 0.44
Q3Y5H1_9GAMC 3C-like protease 1.122e-27 0.42
ENTK_HUMAN TMPRSS15 Enteropeptidase 4.712e-18 0.32
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.093e-17 0.35
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 2.298e-14 0.37
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 2.482e-13 0.29
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 3.922e-13 0.29
R1A_SARS Replicase polyprotein 1a 4.305e-12 0.47
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.105e-10 0.29
TRY1_HUMAN PRSS1 Trypsin-1 9.712e-07 0.32
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.959e-06 0.29
LIPS_HUMAN LIPE Hormone-sensitive lipase 2.498e-06 0.35
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 5.37e-06 0.32
DNAB_MYCTU dnaB Replicative DNA helicase 6.849e-06 0.49

Voxelotor

SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 4.588e-33 0.31

Omidenepag_isopropyl

T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 6.708e-30 0.37
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 2.058e-20 0.47
MMP2_MOUSE Mmp2 72 kDa type IV collagenase 5.429e-20 0.32
MMP9_MOUSE Mmp9 Matrix metalloproteinase-9 5.429e-20 0.32
AMP1_PLAFQ M1 family aminopeptidase 1.421e-18 0.31
MMP25_HUMAN MMP25 Matrix metalloproteinase-25 4.011e-10 0.32
MMP13_RAT Mmp13 Collagenase 3 4.208e-08 0.32
Q8IL11_PLAF7 M17 leucyl aminopeptidase 5.982e-08 0.32
MMP12_MOUSE Mmp12 Macrophage metalloelastase 3.732e-07 0.32
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 2.414e-06 0.36
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.765e-06 0.32

Flortaucipir_F-18

NFAC1_HUMAN NFATC1 Nuclear factor of activated T-cells, cytoplasmic 1 6.124e-26 0.39
T23O_RAT Tdo2 Tryptophan 2,3-dioxygenase 1.801e-20 0.29
KAT8_HUMAN KAT8 Histone acetyltransferase KAT8 3.143e-18 0.29
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 9.992e-16 0.51
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 5.004e-13 0.31
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 5.699e-11 0.29
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 1.52e-09 0.32
GBRA6_RAT Gabra6 Gamma-aminobutyric acid receptor subunit alpha-6 1.582e-09 0.30
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 2.056e-09 0.34
Q25615_ONCVO Chitinase 1.09e-08 0.42
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 2.734e-07 0.36
Q8MMZ8_EIMTE cGMP-dependent protein kinase 3.615e-07 0.31
CSK2B_HUMAN CSNK2B Casein kinase II subunit beta 6.653e-07 0.36
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 9.839e-07 0.33
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 2.726e-06 0.30
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.727e-06 0.39
MK14_RAT Mapk14 Mitogen-activated protein kinase 14 4.51e-06 0.29
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 6.003e-06 0.37

Oxyphenisatin_acetate

ERR3_MOUSE Esrrg Estrogen-related receptor gamma 5.273e-25 0.32
PSB5_YEAST PRE2 Proteasome subunit beta type-5 7.563e-20 0.32
MCR_RAT Nr3c2 Mineralocorticoid receptor 3.587e-17 0.28
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.713e-10 0.32
WNT3A_MOUSE Wnt3a Protein Wnt-3a 2.744e-09 0.37
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.77e-06 0.37

Chromic_nitrate

G3P_RABIT GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.318e-21 0.42
MURA_ECOLI murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4.197e-14 0.38

Diroximel_fumarate

GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 6.654e-21 0.33
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 7.054e-18 0.40
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 2.659e-10 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.861e-09 0.40
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 6.492e-06 0.41

Remdesivir

POLG_HCVBK Genome polyprotein 2.511e-19 0.43
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 3.488e-18 0.29
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 1.431e-10 0.50

Chromous_sulfate

Q9HVB9_PSEAE Carbonic anhydrase 6.741e-19 0.30
CAH_METTE Carbonic anhydrase 3.933e-06 0.30

Potassium_sulfate

Q9HVB9_PSEAE Carbonic anhydrase 6.741e-19 0.30
CAH_METTE Carbonic anhydrase 3.933e-06 0.30

Menadiol_diphosphate

STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 7.438e-14 0.32
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 2.075e-09 0.32
TLR1_MOUSE Tlr1 Toll-like receptor 1 7.185e-06 0.30
TLR2_MOUSE Tlr2 Toll-like receptor 2 7.185e-06 0.30

Ferrous_glycine_sulfate

CAH_METTE Carbonic anhydrase 9.875e-07 0.33