Results of Job: search_25c85398-8a45-4c76-bd36-75060013aa20

Query Target Key Target Name Description P-Value MaxTC

compound_1

A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 4.165e-140 0.75
BCR_HUMAN BCR Breakpoint cluster region protein 2.708e-82 0.47
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 8.381e-75 0.39
INSR_HUMAN INSR Insulin receptor 2.523e-67 0.39
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.824e-64 0.38
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 3.778e-61 0.75
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.623e-60 0.75
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 3.363e-60 0.32
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 4.538e-54 0.75
C3SLB7_ECOLX glmU Bifunctional protein GlmU 6.781e-53 0.34
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 2.318e-52 0.75
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.98e-51 0.75
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.14e-50 0.75
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2.884e-49 0.39
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 1.113e-46 0.39
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.217e-43 0.75
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.445e-43 0.42
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 4.868e-43 0.75
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 6.952e-42 0.59
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.355e-40 0.75
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 7.535e-36 0.35
FAK1_HUMAN PTK2 Focal adhesion kinase 1 2.002e-35 0.35
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.618e-32 0.75
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.968e-31 0.75
LCK_HUMAN LCK Tyrosine-protein kinase Lck 9.927e-30 0.75
MET_HUMAN MET Hepatocyte growth factor receptor 2.542e-29 0.37
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 9.013e-29 0.75
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 6.396e-28 0.41
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.406e-27 0.30
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.983e-26 0.75
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.177e-24 0.75
NR2C2_HUMAN NR2C2 Nuclear receptor subfamily 2 group C member 2 1.863e-24 0.30
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.794e-24 0.55
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.099e-23 0.75
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 4.933e-23 0.75
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 9.045e-23 0.32
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.037e-22 0.75
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.667e-22 0.75
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 5.756e-22 0.45
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.845e-21 0.34
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.137e-21 0.75
TAU_HUMAN MAPT Microtubule-associated protein tau 3.328e-21 0.32
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 4.201e-21 0.33
PIR_HUMAN PIR Pirin 9.32e-20 0.30
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.106e-19 0.31
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.386e-19 0.51
PRIO_SHEEP PRNP Major prion protein 4.729e-19 0.34
SHH_MOUSE Shh Sonic hedgehog protein 6.885e-19 0.42
MTSI_SPISQ sssIM CPG DNA methylase 1.174e-18 0.31
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 7.185e-18 0.75
TTK_HUMAN TTK Dual specificity protein kinase TTK 9.005e-18 0.36
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 3.123e-17 0.38
CHLE_HORSE BCHE Cholinesterase 4.86e-17 0.39
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.945e-17 0.32
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.11e-16 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.11e-16 0.42
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 2.22e-16 0.42
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 2.22e-16 0.37
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 3.331e-16 0.75
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.441e-16 0.75
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 6.661e-16 0.59
HCK_HUMAN HCK Tyrosine-protein kinase HCK 2.331e-15 0.75
CCNA1_HUMAN CCNA1 Cyclin-A1 6.328e-15 0.37
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 6.772e-15 0.28
INHBA_MOUSE Inhba Inhibin beta A chain 6.772e-15 0.28
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.044e-14 0.32
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.288e-14 0.75
AURKA_HUMAN AURKA Aurora kinase A 2.431e-14 0.34
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 1.463e-13 0.33
AURKA_MOUSE Aurka Aurora kinase A 2.416e-13 0.29
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 3.271e-13 0.30
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 3.924e-13 0.75
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 7.476e-13 0.31
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.036e-12 0.31
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 1.154e-12 0.31
ACES_ELEEL ache Acetylcholinesterase 1.373e-12 0.39
BRDT_HUMAN BRDT Bromodomain testis-specific protein 2.074e-12 0.30
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 2.431e-12 0.75
AURKB_HUMAN AURKB Aurora kinase B 2.665e-12 0.34
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 2.947e-12 0.75
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 3.726e-12 0.29
BLK_HUMAN BLK Tyrosine-protein kinase Blk 4.531e-12 0.75
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 4.89e-12 0.75
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 6.433e-12 0.75
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 6.712e-12 0.31
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 8.237e-12 0.30
CCNK_HUMAN CCNK Cyclin-K 1.046e-11 0.32
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.088e-11 0.75
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 1.163e-11 0.75
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.465e-11 0.37
A4_HUMAN APP Amyloid-beta precursor protein 1.821e-11 0.32
CAH15_MOUSE Ca15 Carbonic anhydrase 15 2.046e-11 0.75
SMO_HUMAN SMO Smoothened homolog 2.199e-11 0.33
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 3.806e-11 0.35
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 6.122e-11 0.42
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 6.878e-11 0.29
CAH6_HUMAN CA6 Carbonic anhydrase 6 7.382e-11 0.75
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 8.239e-11 0.42
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 1.351e-10 0.28
BKRB2_CAVPO BDKRB2 B2 bradykinin receptor 1.75e-10 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.842e-10 0.34
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.072e-10 0.42
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 2.225e-10 0.32
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 2.872e-10 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 3.612e-10 0.36
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 4.398e-10 0.29
CAH3_HUMAN CA3 Carbonic anhydrase 3 5.451e-10 0.75
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 5.915e-10 0.31
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 6.517e-10 0.34
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 6.92e-10 0.59
HSF1_HUMAN HSF1 Heat shock factor protein 1 9.89e-10 0.30
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 2.194e-09 0.75
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 6.117e-09 0.31
SYK_HUMAN KARS1 Lysine--tRNA ligase 6.254e-09 0.29
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 6.82e-09 0.42
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 8.412e-09 0.35
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 8.736e-09 0.31
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.035e-08 0.75
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.432e-08 0.36
YES_HUMAN YES1 Tyrosine-protein kinase Yes 2.011e-08 0.59
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 2.5e-08 0.29
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 2.888e-08 0.75
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 3.024e-08 0.37
CHLE_HUMAN BCHE Cholinesterase 3.259e-08 0.39
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 3.936e-08 0.36
O97467_PLAFA ht1 Hexose transporter 1 3.974e-08 0.35
O61059_LEIME LmGT2 Glucose transporter 4.569e-08 0.35
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 4.801e-08 0.40
CCNC_HUMAN CCNC Cyclin-C 4.837e-08 0.31
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 6.126e-08 0.31
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 7.382e-08 0.35
MYO3A_HUMAN MYO3A Myosin-IIIa 7.387e-08 0.29
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 9.112e-08 0.32
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 1.104e-07 0.28
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 1.107e-07 0.31
FRK_HUMAN FRK Tyrosine-protein kinase FRK 1.171e-07 0.75
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 1.25e-07 0.30
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 1.25e-07 0.30
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 1.301e-07 0.32
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 1.321e-07 0.36
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.671e-07 0.34
MYO3B_HUMAN MYO3B Myosin-IIIb 1.721e-07 0.29
GAK_HUMAN GAK Cyclin-G-associated kinase 1.773e-07 0.75
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.921e-07 0.34
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 2.014e-07 0.42
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 2.331e-07 0.42
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 2.677e-07 0.32
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 2.723e-07 0.75
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 3.137e-07 0.28
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 3.499e-07 0.75
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 3.629e-07 0.29
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.687e-07 0.32
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 5.757e-07 0.75
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 7.045e-07 0.29
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 7.045e-07 0.29
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 8.139e-07 0.35
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 8.879e-07 0.32
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 9.973e-07 0.28
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.183e-06 0.30
BKRB2_HUMAN BDKRB2 B2 bradykinin receptor 1.338e-06 0.30
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.492e-06 0.31
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.5e-06 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.571e-06 0.30
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1.578e-06 0.33
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 1.748e-06 0.30
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 2.109e-06 0.42
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.774e-06 0.35
NK2R_MOUSE Tacr2 Substance-K receptor 3.095e-06 0.31
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 3.18e-06 0.32
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 3.324e-06 0.33
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 3.753e-06 0.42
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.596e-06 0.29
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 4.962e-06 0.31
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 5.277e-06 0.31
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 5.28e-06 0.45
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 5.549e-06 0.42
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 6.306e-06 0.42
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 6.507e-06 0.75
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.726e-06 0.32
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 9.1e-06 0.33
ACES_HUMAN ACHE Acetylcholinesterase 9.936e-06 0.39