Results of Job: search_274ac860-e3b7-4c17-9524-90a455737d94

Query Target Key Target Name Description P-Value MaxTC

Icaritin

PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 8.596e-05 1.00
NANH_CLOPF nanH Sialidase 1.69e-84 0.49
TYRO_MOUSE Tyr Tyrosinase 1.664e-50 0.34
VE6_HPV16 E6 Protein E6 1.195e-49 0.32
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 5.593e-46 0.58
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 4.538e-44 0.35
DDL_HELPH ddl D-alanine--D-alanine ligase 4.538e-44 0.35
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 5.081e-44 0.46
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.743e-42 0.55
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 1.28e-40 0.32
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 5.696e-40 0.36
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 2.801e-36 0.40
NANH_VIBCH nanH Sialidase 3.221e-35 0.35
O96394_LEIAM Arginase 5.374e-35 0.35
CBS_HUMAN CBS Cystathionine beta-synthase 8.874e-34 0.34
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 2.019e-33 0.37
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.08e-31 0.40
AOFA_MOUSE Maoa Amine oxidase [flavin-containing] A 1.264e-30 0.31
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 2.586e-28 0.35
AOX_TRYBB AOX Alternative oxidase, mitochondrial 8.746e-28 0.33
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 5.245e-27 0.33
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.021e-25 0.44
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.808e-25 0.51
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.158e-24 0.30
DCOR_HUMAN ODC1 Ornithine decarboxylase 2.529e-23 0.31
LRP6_HUMAN LRP6 Low-density lipoprotein receptor-related protein 6 7.194e-22 0.29
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 6.654e-21 0.33
SYN1_BOVIN SYN1 Synapsin-1 6.654e-21 0.33
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.313e-20 0.40
PERL_BOVIN LPO Lactoperoxidase 1.024e-19 0.35
R1AB_SARS rep Replicase polyprotein 1ab 2.459e-19 0.35
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 4.43e-19 0.30
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 1.008e-18 0.40
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.648e-18 0.30
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 1.11e-16 0.37
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 8.882e-16 0.30
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 3.109e-15 0.38
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 3.442e-15 0.29
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 1.72e-13 0.29
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 3.922e-13 0.29
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.43e-12 0.59
REST_BORBU resT Telomere resolvase ResT 5.427e-12 0.29
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 6.72e-12 0.30
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 8.488e-12 0.44
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.101e-11 0.40
TF65_HUMAN RELA Transcription factor p65 2.689e-11 0.42
IL2_HUMAN IL2 Interleukin-2 3.169e-11 0.33
MDH_THETH mdh Malate dehydrogenase 4.673e-11 0.35
TYRO_HUMAN TYR Tyrosinase 8.124e-11 0.42
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.028e-10 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.028e-10 0.29
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.105e-10 0.29
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.352e-10 0.35
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 2.292e-10 0.35
XPO1_HUMAN XPO1 Exportin-1 2.316e-10 0.41
CATL2_HUMAN CTSV Cathepsin L2 2.694e-10 0.42
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.861e-09 0.50
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 7.76e-09 0.35
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 1.106e-08 0.36
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.689e-08 0.58
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.147e-08 0.47
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 4.188e-08 0.35
HSC82_YEAST HSC82 ATP-dependent molecular chaperone HSC82 5.058e-08 0.28
EGLN1_RAT Egln1 Egl nine homolog 1 5.265e-08 0.31
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 5.309e-08 0.32
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.163e-07 0.37
LGUL_HUMAN GLO1 Lactoylglutathione lyase 2.473e-07 0.35
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.905e-07 0.35
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.253e-07 0.34
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 3.692e-07 0.34
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 4.157e-07 0.47
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.173e-07 0.41
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.565e-07 0.40
ASAH1_HUMAN ASAH1 Acid ceramidase 4.734e-07 0.32
NOX4_HUMAN NOX4 NADPH oxidase 4 6.466e-07 0.38
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 8.066e-07 0.35
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 9.875e-07 0.33
B4URF0_I33A0 Neuraminidase 1.129e-06 0.49
CP19A_HUMAN CYP19A1 Aromatase 1.327e-06 0.72
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.765e-06 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.944e-06 0.40
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 4.265e-06 0.35
CAH3_HUMAN CA3 Carbonic anhydrase 3 7.331e-06 0.35
PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 8.019e-06 0.73
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 8.176e-06 0.28
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 9.92e-06 0.47

Hypoxanthine

Q8T9Z7_PLAFA PNP Purine nucleoside phosphorylase 1.697e-112 0.37
PNPH_HUMAN PNP Purine nucleoside phosphorylase 1.77e-78 0.37
PNPH_RAT Pnp Purine nucleoside phosphorylase 6.448e-50 0.57
GUAD_HUMAN GDA Guanine deaminase 7.348e-43 0.47
5HT3C_HUMAN HTR3C 5-hydroxytryptamine receptor 3C 3.458e-38 0.30
5HT3E_HUMAN HTR3E 5-hydroxytryptamine receptor 3E 3.458e-38 0.30
MTIP_PSEAE S-methyl-5'-thioinosine phosphorylase 1.041e-36 0.31
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 2.091e-33 0.37
PNPH_BOVIN PNP Purine nucleoside phosphorylase 2.179e-27 0.46
AA1R_CAVPO ADORA1 Adenosine receptor A1 1.343e-19 0.42
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 2.326e-17 0.38
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 6.661e-16 0.30
AA2BR_RAT Adora2b Adenosine receptor A2b 1.416e-13 0.33
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 2.511e-10 0.38
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 4.434e-09 0.30
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 1.215e-08 0.32
XDH_RAT Xdh Xanthine dehydrogenase/oxidase 2.784e-08 0.45
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 7.649e-07 0.38
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 1.231e-06 0.38

Hydroxyquercitrin

O96394_LEIAM Arginase 2.528e-79 0.79
FAS_CHICK FASN Fatty acid synthase 3.249e-72 0.58
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 6.143e-62 0.46
CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 1.565e-58 0.30
PDIA1_HUMAN P4HB Protein disulfide-isomerase 2.284e-57 0.79
AK1CL_MOUSE Akr1c21 Aldo-keto reductase family 1 member C21 3.404e-56 0.45
DDL_HELPH ddl D-alanine--D-alanine ligase 3.404e-56 0.45
VE6_HPV16 E6 Protein E6 2.387e-52 0.35
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 6.669e-49 0.46
FPS_FUJSV V-FPS Tyrosine-protein kinase transforming protein Fps 4.538e-44 0.35
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.55e-43 0.45
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.06e-41 0.34
TOP1_RAT Top1 DNA topoisomerase 1 4.694e-40 0.32
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.877e-39 0.79
SYN1_BOVIN SYN1 Synapsin-1 1.021e-36 0.60
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 5.069e-36 0.45
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 2.397e-35 0.45
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.61e-32 0.35
NANH_CLOPF nanH Sialidase 2.217e-26 0.45
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 3.656e-26 0.32
ARGI1_RAT Arg1 Arginase-1 9.218e-26 0.32
PPAC_BOVIN ACP1 Low molecular weight phosphotyrosine protein phosphatase 6.731e-25 0.31
IL2_HUMAN IL2 Interleukin-2 4.713e-24 0.42
R1AB_SARS rep Replicase polyprotein 1ab 1.499e-21 0.45
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.382e-20 0.67
AMY1A_HUMAN AMY1A Alpha-amylase 1 5.368e-18 0.34
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.11e-16 0.45
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.11e-16 0.46
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 4.441e-16 0.31
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 5.551e-16 0.49
CBS_HUMAN CBS Cystathionine beta-synthase 6.661e-16 0.44
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 6.661e-16 0.45
B4EH87_BURCJ Lectin 7.772e-16 0.30
NOX4_HUMAN NOX4 NADPH oxidase 4 1.776e-15 0.59
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 5.551e-15 0.51
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 9.437e-15 0.46
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.821e-14 0.45
MDH_THETH mdh Malate dehydrogenase 6.106e-14 0.45
PERL_BOVIN LPO Lactoperoxidase 6.106e-14 0.45
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 4.657e-13 0.45
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 3.713e-12 0.79
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 5.908e-12 0.45
LGUL_HUMAN GLO1 Lactoylglutathione lyase 9.399e-12 0.45
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 8.4e-11 0.32
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.052e-10 0.35
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 1.639e-10 0.45
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 2.98e-10 0.32
CP2C8_HUMAN CYP2C8 Cytochrome P450 2C8 3.603e-10 0.45
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 3.761e-10 0.45
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 4.715e-10 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 5.156e-10 0.79
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 2.227e-09 0.60
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 2.365e-09 0.64
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.656e-09 0.79
Q7ZJM1_9HIV1 pol Integrase 4.026e-09 0.60
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 4.264e-09 0.45
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 8.171e-09 0.79
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 1.568e-08 0.45
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 3.243e-08 0.30
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 5.662e-08 0.34
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 6.408e-08 0.36
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 9.472e-08 0.35
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.186e-07 0.67
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 2.398e-07 0.47
IL5_MOUSE Il5 Interleukin-5 1.44e-06 0.35
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.453e-06 0.45
TERT_HUMAN TERT Telomerase reverse transcriptase 2.818e-06 0.36
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 4.237e-06 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 5.987e-06 0.45
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 6.911e-06 0.45

Hydroquinone

H9TVJ1_CHISP TyR1 4.303e-67 0.44
O87171_SPHPI lsdA Dioxygenase 3.773e-53 0.33
SSDH_HUMAN ALDH5A1 Succinate-semialdehyde dehydrogenase, mitochondrial 3.077e-50 0.40
Q2PCB5_DICLA ca Carbonic anhydrase 2.881e-45 0.50
ESR2_HUMAN ESR2 Estrogen receptor beta 7.795e-35 0.57
ESR1_HUMAN ESR1 Estrogen receptor 1.561e-32 0.73
GABT_HUMAN ABAT 4-aminobutyrate aminotransferase, mitochondrial 3.098e-32 0.40
ESR1_MOUSE Esr1 Estrogen receptor 7.174e-27 0.30
ESR2_MOUSE Esr2 Estrogen receptor beta 7.174e-27 0.30
Q86PR3_AEDAE SCP-2 Sterol carrier protein 2 5.379e-25 0.31
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.786e-23 0.62
MYG_HUMAN MB Myoglobin 7.967e-22 0.42
ESR2_RAT Esr2 Estrogen receptor beta 2.03e-20 0.32
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.72e-19 0.38
DHPR_RAT Qdpr Dihydropteridine reductase 9.801e-19 0.35
DHPR_HUMAN QDPR Dihydropteridine reductase 1.209e-17 0.35
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.11e-16 0.39
TYSY_ENTFA thyA Thymidylate synthase 4.441e-15 0.29
ESR1_RAT Esr1 Estrogen receptor 3.54e-12 0.30
A4_HUMAN APP Amyloid-beta precursor protein 1.483e-11 0.47
MTSI_SPISQ sssIM CPG DNA methylase 1.859e-11 0.36
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 4.49e-11 0.42
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 5.227e-11 0.47
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.412e-11 0.35
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.441e-10 0.33
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.98e-10 0.50
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.407e-10 0.50
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 3.283e-10 0.36
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 1.52e-09 0.32
CAH3_BOVIN CA3 Carbonic anhydrase 3 1.663e-09 0.42
TYRO_HUMAN TYR Tyrosinase 4.723e-09 0.50
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 6.379e-09 0.50
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 6.971e-09 0.38
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 7.824e-09 0.42
DOPO_RAT Dbh Dopamine beta-hydroxylase 1.322e-08 0.29
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.964e-08 0.36
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 3.137e-08 0.42
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 3.82e-08 0.32
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.194e-08 0.47
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 5.7e-08 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.784e-08 0.50
SHBG_HUMAN SHBG Sex hormone-binding globulin 7.058e-08 0.38
CAH14_HUMAN CA14 Carbonic anhydrase 14 8.78e-08 0.50
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.031e-07 0.29
TTHY_HUMAN TTR Transthyretin 1.534e-07 0.42
Q43570_TOBAC NtBBF1.1 Zn finger protein 3.629e-07 0.29
AHR_RABIT AHR Aryl hydrocarbon receptor 4.838e-07 0.42
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.521e-07 0.31
CAN_CANAL NCE103 Carbonic anhydrase 6.041e-07 0.47
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 6.072e-07 0.31
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 6.838e-07 0.32
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 7.451e-07 0.36
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.051e-07 0.44
CAH6_HUMAN CA6 Carbonic anhydrase 6 9.103e-07 0.50
H9B8T9_CAPHI CTSB Cathepsin B 1.003e-06 0.40
A0A060INS8_CAPHI CTSH Cathepsin H 2.015e-06 0.40
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 2.257e-06 0.44
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 3.458e-06 0.50
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 7.112e-06 0.29
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 9.449e-06 0.31