Results of Job: search_2cb700cd-c4c6-4f56-80bb-8d6468fd2889

Query Target Key Target Name Description P-Value MaxTC

compound_1

PRIO_SHEEP PRNP Major prion protein 2.919e-83 0.47
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 1.326e-70 0.37
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 3.507e-63 0.39
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.219e-61 0.49
BACE2_MOUSE Bace2 Beta-secretase 2 4.829e-49 0.31
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 1.136e-43 0.43
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 3.01e-43 0.39
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.814e-42 0.49
LUCI_AQULA Luciferin 4-monooxygenase 4.696e-42 0.36
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 1.368e-41 0.39
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 1.143e-39 0.42
HCN2_HUMAN HCN2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 3.104e-39 0.31
HCN3_HUMAN HCN3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 3.104e-39 0.31
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 8.338e-39 0.35
SYK_HUMAN KARS1 Lysine--tRNA ligase 1.114e-37 0.42
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 3.747e-35 0.51
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 6.575e-33 0.41
ACVR1_HUMAN ACVR1 Activin receptor type-1 4.929e-29 0.42
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 5.636e-29 0.37
BMP4_MOUSE Bmp4 Bone morphogenetic protein 4 1.665e-28 0.34
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 2.28e-28 0.36
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 4.726e-28 0.34
ACVR1_MOUSE Acvr1 Activin receptor type-1 2.325e-27 0.34
BACE1_MOUSE Bace1 Beta-secretase 1 7.719e-27 0.31
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 1.981e-26 0.41
FSHR_RAT Fshr Follicle-stimulating hormone receptor 5.827e-26 0.32
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.572e-25 0.35
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.325e-25 0.38
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 2.834e-24 0.44
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 6.57e-23 0.32
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 9.128e-22 0.31
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 6.756e-21 0.34
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 1.335e-20 0.32
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 4.236e-19 0.34
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 6.741e-19 0.30
KHK_HUMAN KHK Ketohexokinase 9.207e-19 0.36
CCNA1_HUMAN CCNA1 Cyclin-A1 1.022e-18 0.36
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.719e-18 0.35
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 7.329e-18 0.34
C3SLB7_ECOLX glmU Bifunctional protein GlmU 9.803e-18 0.32
CCNA2_HUMAN CCNA2 Cyclin-A2 1.135e-17 0.39
AURKA_HUMAN AURKA Aurora kinase A 3.757e-17 0.38
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.11e-16 0.40
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.11e-16 0.35
CATK_RABIT CTSK Cathepsin K 2.22e-16 0.40
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 4.441e-16 0.36
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.551e-16 0.30
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 1.11e-15 0.34
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 1.665e-15 0.34
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.776e-15 0.36
O97467_PLAFA ht1 Hexose transporter 1 2.109e-15 0.47
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 2.998e-15 0.36
O61059_LEIME LmGT2 Glucose transporter 1.565e-14 0.47
ALK_HUMAN ALK ALK tyrosine kinase receptor 2.232e-14 0.34
ISPT_STRPN uppS Isoprenyl transferase 2.409e-14 0.32
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 4.186e-14 0.33
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 1.864e-13 0.39
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.372e-13 0.34
V2R_RAT Avpr2 Vasopressin V2 receptor 7.578e-13 0.30
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 1.016e-12 0.33
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.431e-12 0.36
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.731e-12 0.31
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.516e-12 0.33
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 2.757e-12 0.30
ACV1B_HUMAN ACVR1B Activin receptor type-1B 2.845e-12 0.34
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 3.043e-12 0.40
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 4.269e-12 0.37
AUKBB_XENLA aurkb-b Aurora kinase B-B 1.119e-11 0.28
SMO_HUMAN SMO Smoothened homolog 1.155e-11 0.39
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 1.722e-11 0.35
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.76e-11 0.44
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.813e-11 0.38
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.497e-11 0.40
O96526_LEIMA CRK3 Cdc2-related kinase 4.289e-11 0.33
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.911e-11 0.41
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 6.518e-11 0.33
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.791e-11 0.44
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 8.903e-11 0.42
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 1.381e-10 0.37
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.396e-10 0.44
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 1.897e-10 0.41
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.513e-10 0.40
YES_HUMAN YES1 Tyrosine-protein kinase Yes 3.053e-10 0.34
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.507e-10 0.29
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 4.164e-10 0.34
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 4.639e-10 0.40
HCK_HUMAN HCK Tyrosine-protein kinase HCK 1.003e-09 0.35
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 1.343e-09 0.33
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 1.427e-09 0.31
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 1.56e-09 0.42
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.654e-09 0.38
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.21e-09 0.35
BACE2_RAT Bace2 Beta-secretase 2 4.515e-09 0.28
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 5.012e-09 0.34
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 6.13e-09 0.42
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 6.765e-09 0.35
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 8.618e-09 0.34
V2R_HUMAN AVPR2 Vasopressin V2 receptor 1.511e-08 0.31
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.703e-08 0.30
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.884e-08 0.36
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 1.922e-08 0.33
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 1.922e-08 0.33
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 2.357e-08 0.30
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.505e-08 0.37
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.748e-08 0.35
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.77e-08 0.35
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 3.26e-08 0.32
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 3.624e-08 0.34
REV1_HUMAN REV1 DNA repair protein REV1 3.632e-08 0.30
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.904e-08 0.31
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 5.03e-08 0.38
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 5.503e-08 0.40
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 6.334e-08 0.36
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 6.77e-08 0.33
BACE1_HUMAN BACE1 Beta-secretase 1 7.31e-08 0.39
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 9.135e-08 0.30
FAK1_HUMAN PTK2 Focal adhesion kinase 1 9.725e-08 0.39
RCOR1_HUMAN RCOR1 REST corepressor 1 1.057e-07 0.31
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.086e-07 0.37
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.324e-07 0.38
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.383e-07 0.36
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.404e-07 0.33
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.405e-07 0.33
Q25615_ONCVO Chitinase 2.271e-07 0.31
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 3.341e-07 0.32
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 3.647e-07 0.32
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 4.27e-07 0.32
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 4.756e-07 0.30
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 4.8e-07 0.29
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 4.806e-07 0.33
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 5.762e-07 0.40
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 8.09e-07 0.32
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 8.502e-07 0.33
HDAC1_HUMAN HDAC1 Histone deacetylase 1 9.008e-07 0.44
SMO_MOUSE Smo Smoothened homolog 9.18e-07 0.38
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 9.77e-07 0.33
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.293e-06 0.32
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.368e-06 0.37
FA10_HUMAN F10 Coagulation factor X 1.597e-06 0.43
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 1.943e-06 0.36
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 2.01e-06 0.33
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.243e-06 0.41
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 2.247e-06 0.35
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.602e-06 0.39
ASIC3_HUMAN ASIC3 Acid-sensing ion channel 3 3.75e-06 0.41
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 3.882e-06 0.31
INCE_HUMAN INCENP Inner centromere protein 5.293e-06 0.32
AURKB_HUMAN AURKB Aurora kinase B 6.274e-06 0.33
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 7.923e-06 0.42
PIM3_HUMAN PIM3 Serine/threonine-protein kinase pim-3 8.19e-06 0.39
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 8.402e-06 0.31
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 8.574e-06 0.31
CCNH_HUMAN CCNH Cyclin-H 8.635e-06 0.36