Results of Job: search_2dc43943-0971-42c8-87c0-d0a2de91921d

Query Target Key Target Name Description P-Value MaxTC

Aliskiren

RENI_CALJA REN Renin 0 1.00
Q7M3D2_RABIT Renin 2.9e-124 1.00
RENI_HUMAN REN Renin 1.436e-107 1.00
RENI_MACFA REN Renin 1.293e-78 1.00
RENI_MACMU REN Renin 5.121e-61 1.00
RENI1_MOUSE Ren1 Renin-1 2.191e-35 1.00
RENI_RAT Ren1 Renin 7.772e-16 1.00
Q9YQ12_9HIV1 protease Protease 0.01497 1.00
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 4.998e-35 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.965e-25 0.32
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 1.002e-10 0.31
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 1.002e-10 0.31
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 1.002e-10 0.31
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 1.002e-10 0.31
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 1.002e-10 0.31
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 1.002e-10 0.31
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 1.002e-10 0.31
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 1.002e-10 0.31
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 1.002e-10 0.31
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 1.002e-10 0.31
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 1.002e-10 0.31
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 1.002e-10 0.31
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 1.002e-10 0.31
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.761e-10 0.30
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 2.163e-10 0.31
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.437e-10 0.30
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 7.787e-09 0.31
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 6.977e-08 0.34
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.761e-07 0.31
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.166e-07 0.31
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 3.534e-07 0.31

Empagliflozin

SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 0 1.00
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 4.194e-144 1.00
SC5A2_MOUSE Slc5a2 Sodium/glucose cotransporter 2 2.057e-133 0.56
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 2.715e-98 0.66
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 2.715e-52 0.66
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.83e-51 0.35
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 5.591e-39 0.66
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 1.007e-35 0.28
B4EH87_BURCJ Lectin 1.136e-31 0.34
IL2_HUMAN IL2 Interleukin-2 3.109e-15 0.30
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 4.441e-15 0.29
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 7.867e-13 0.33
Q53I59_TRYCR PDEC Phosphodiesterase 4.023e-12 0.30
TYRO_HUMAN TYR Tyrosinase 3.756e-10 0.33
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 8.577e-10 0.28
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 1.104e-09 0.28
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 4.053e-09 0.28
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.493e-08 0.28
Q4VQ11_PIG Adenosine receptor A1 1.574e-08 0.31
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.239e-08 0.33
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 6.665e-08 0.31
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.106e-07 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.408e-07 0.28
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5.689e-06 0.31

Palbociclib

CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 0 1.00
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 0 1.00
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 3.335e-237 1.00
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 1.436e-213 1.00
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 1.267e-156 1.00
CCNA2_HUMAN CCNA2 Cyclin-A2 9.207e-57 1.00
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 7.023e-44 1.00
CCNT1_HUMAN CCNT1 Cyclin-T1 1.48e-21 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.396e-20 1.00
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 5.551e-16 1.00
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 3.363e-13 1.00
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 3.74e-10 1.00
ALK_HUMAN ALK ALK tyrosine kinase receptor 2.255e-09 1.00
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.434e-06 1.00
RON_HUMAN MST1R Macrophage-stimulating protein receptor 3.38e-05 1.00
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 4e-05 1.00
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 9.235e-05 1.00
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 0.0001621 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 0.0002944 1.00
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 0.0004626 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 0.0005065 1.00
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 0.0007204 1.00
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 0.0008998 1.00
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.003589 1.00
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.003961 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 0.008025 1.00
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 0.008487 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 0.01866 1.00
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 0.02105 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 0.02305 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 0.03222 1.00
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 0.04012 1.00
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 0.0731 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 0.1311 1.00
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 0.5075 1.00
MET_HUMAN MET Hepatocyte growth factor receptor 0.6854 1.00
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 0.7699 1.00
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 8.19e-75 0.66
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 6.189e-49 0.64
CCNH_HUMAN CCNH Cyclin-H 4.952e-46 0.45
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.861e-42 0.66
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 5.023e-31 0.64
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 5.023e-31 0.64
CCNA1_HUMAN CCNA1 Cyclin-A1 6.964e-29 0.82
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 3.416e-24 0.36
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 1.931e-23 0.45
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 5.046e-19 0.35
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 4.568e-17 0.35
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.22e-16 0.44
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 2.467e-13 0.36
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 1.896e-12 0.40
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8.337e-11 0.29
PDE7B_HUMAN PDE7B cAMP-specific 3',5'-cyclic phosphodiesterase 7B 1.763e-10 0.35
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 3.41e-10 0.34
PDE7A_HUMAN PDE7A High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 9.692e-10 0.36
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.829e-09 0.38
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.329e-08 0.32
Q8RL90_PSEAI ampC Beta-lactamase 3.396e-08 0.40
Q93LQ9_KLEPN KPC-2 Beta-lactamase 4.212e-08 0.40
WEE1_HUMAN WEE1 Wee1-like protein kinase 5.85e-08 0.33
Q8VBU5_MOUSE Pde4b Phosphodiesterase 7.763e-08 0.36
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 8.075e-08 0.34
TTK_HUMAN TTK Dual specificity protein kinase TTK 1.509e-07 0.43
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 2.509e-07 0.40
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 2.74e-07 0.43
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 3.244e-07 0.31
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 7.637e-07 0.29
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.619e-06 0.31
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 1.743e-06 0.29
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 2.619e-06 0.30
AURKA_HUMAN AURKA Aurora kinase A 4.058e-06 0.34
AURKB_HUMAN AURKB Aurora kinase B 4.599e-06 0.33
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 5.514e-06 0.34

Vorapaxar

PAR1_HUMAN F2R Proteinase-activated receptor 1 3.84e-281 1.00
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 3.916e-09 0.32
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 6.868e-06 0.31

Olaparib

PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 2.601e-278 1.00
PARP6_HUMAN PARP6 Protein mono-ADP-ribosyltransferase PARP6 3.782e-89 1.00
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 1.089e-50 1.00
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 2.541e-32 1.00
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 3.937e-30 1.00
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 1.621e-27 1.00
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.375e-10 1.00
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 1.963e-08 1.00
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 6.739e-07 1.00
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 5.488e-40 0.31
BKRB1_MACMU BDKRB1 B1 bradykinin receptor 9.362e-36 0.28
TP53B_HUMAN TP53BP1 TP53-binding protein 1 2.549e-26 0.30
CCNC_HUMAN CCNC Cyclin-C 1.367e-22 0.36
Q1HEC0_RAT Acetyl-Coenzyme A carboxylase 2 3.809e-18 0.29
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 1.032e-17 0.31
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.11e-16 0.32
HS90B_HUMAN HSP90AB1 Heat shock protein HSP 90-beta 1.887e-15 0.32
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 2.054e-14 0.36
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 5.174e-14 0.33
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 7.139e-13 0.33
HRH3_CAVPO HRH3 Histamine H3 receptor 1.239e-12 0.35
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 1.47e-12 0.32
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 8.998e-12 0.32
HRH1_HUMAN HRH1 Histamine H1 receptor 1.855e-11 0.38
PPCE_HUMAN PREP Prolyl endopeptidase 1.9e-11 0.32
Q3Y5H1_9GAMC 3C-like protease 7.208e-10 0.31
MTLR_HUMAN MLNR Motilin receptor 7.95e-10 0.34
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.012e-09 0.28
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.611e-09 0.48
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.722e-09 0.28
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1.343e-08 0.32
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 2.332e-08 0.30
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 8.084e-08 0.30
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 9.053e-08 0.38
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.074e-07 0.38
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 3.169e-07 0.30
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 5.408e-07 0.37
AGP1_YEAST AGP1 General amino acid permease AGP1 3.742e-06 0.30
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 4.804e-06 0.30
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 7.652e-06 0.28

Daclatasvir

Q5L478_9HEPC NS5A Nonstructural protein 5A 1.107e-277 1.00
POLG_HCVCO Genome polyprotein 2.119e-75 0.56
ELNE_HUMAN ELANE Neutrophil elastase 8.767e-57 0.43
DEF_MYCTU def Peptide deformylase 1.226e-56 0.35
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 5.589e-38 0.33
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 6.533e-37 0.38
DEF1A_ARATH PDF1A Peptide deformylase 1A, chloroplastic/mitochondrial 2.333e-36 0.29
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 7.421e-35 0.52
MLX_HUMAN MLX Max-like protein X 8.257e-33 0.35
CTRA_BOVIN Chymotrypsinogen A 3.994e-28 0.38
TF_HUMAN F3 Tissue factor 2.289e-26 0.32
F1SH20_PIG TRHDE Uncharacterized protein 1.251e-20 0.29
FA7_HUMAN F7 Coagulation factor VII 1.004e-19 0.32
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.512e-18 0.29
CMA1_HUMAN CMA1 Chymase 1.277e-17 0.38
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.11e-15 0.45
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 1.332e-15 0.29
LGMN_HUMAN LGMN Legumain 4.319e-14 0.31
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 6.195e-14 0.31
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 2.788e-13 0.29
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.807e-12 0.31
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 2.807e-12 0.31
TRFR_HUMAN TRHR Thyrotropin-releasing hormone receptor 7.163e-12 0.29
NEP_RABIT MME Neprilysin 2.058e-11 0.38
FA11_HUMAN F11 Coagulation factor XI 4.115e-11 0.40
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.13e-11 0.34
PPCE_BOVIN PREP Prolyl endopeptidase 4.265e-11 0.35
CATG_HUMAN CTSG Cathepsin G 3.286e-10 0.38
ACE_RAT Ace Angiotensin-converting enzyme 4.485e-10 0.38
CTRC_HUMAN CTRC Chymotrypsin-C 1.101e-09 0.43
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.629e-09 0.33
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 2.851e-09 0.29
Q1A7N1_CANLF TRPM8 Transient receptor potential M8 protein 1.455e-08 0.37
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.043e-08 0.43
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.806e-08 0.46
Q9R297_RAT Mlnr Motilin receptor 1.967e-07 0.29
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 2.598e-07 0.31
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 2.868e-07 0.32
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 2.994e-07 0.28
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 4.12e-07 0.29
CCNC_HUMAN CCNC Cyclin-C 7.994e-07 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 1.064e-06 0.32
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 1.123e-06 0.31
Q9BRH5_HUMAN DGAT1 DGAT1 protein 1.21e-06 0.28
TRY1_BOVIN Cationic trypsin 1.514e-06 0.36
DEF_STAAU def Peptide deformylase 1.76e-06 0.29
KLK5_HUMAN KLK5 Kallikrein-5 2.088e-06 0.29
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 3.203e-06 0.29
NEP_RAT Mme Neprilysin 4.143e-06 0.32
POLG_HCVNZ Genome polyprotein 5.797e-06 0.47

Carmofur

ASAH1_RAT Asah1 Acid ceramidase 6.287e-269 1.00
ASAH1_HUMAN ASAH1 Acid ceramidase 4.147e-50 1.00
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 3.618e-07 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 7.921e-46 0.39
GRIA1_RAT Gria1 Glutamate receptor 1 1.36e-44 0.37
PA2A1_NAJMO Acidic phospholipase A2 CM-I 3.543e-39 0.31
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 6.833e-39 0.31
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 7.472e-36 0.34
TYSY_MYCTU thyA Thymidylate synthase ThyA 1.377e-35 0.28
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 3.99e-34 0.39
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 3.553e-32 0.33
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 1.652e-27 0.30
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 1.394e-24 0.33
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 1.394e-24 0.33
PSBA_SPIOL psbA Photosystem II protein D1 2.695e-24 0.30
GRIA1_HUMAN GRIA1 Glutamate receptor 1 1.358e-20 0.37
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 6.382e-19 0.42
UNG_HUMAN UNG Uracil-DNA glycosylase 9.056e-18 0.28
PA_I000X PA Polymerase acidic protein 6.661e-16 0.30
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 3.773e-13 0.31
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 1.608e-12 0.31
GPR84_HUMAN GPR84 G-protein coupled receptor 84 4.25e-12 0.36
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 4.787e-12 0.35
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 2.872e-11 0.36
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.049e-11 0.40
ERG1_RAT Sqle Squalene monooxygenase 9.763e-11 0.28
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 1.544e-10 0.36
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.388e-10 0.29
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 6.881e-10 0.34
A1ZA98_DROME Jhe Carboxylic ester hydrolase 9.06e-10 0.31
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.635e-09 0.29
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.102e-08 0.31
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 3.135e-08 0.38
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 3.985e-08 0.29
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 4.168e-08 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.135e-07 0.31
MGLL_RAT Mgll Monoglyceride lipase 1.924e-07 0.33
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 3.12e-07 0.29
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 4.353e-07 0.37
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.961e-07 0.31
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 9.396e-07 0.29
GRIA4_RAT Gria4 Glutamate receptor 4 1.075e-06 0.37
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.569e-06 0.31
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.858e-06 0.31
TLR1_MOUSE Tlr1 Toll-like receptor 1 2.974e-06 0.32
TLR2_MOUSE Tlr2 Toll-like receptor 2 2.974e-06 0.32
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.188e-06 0.32
GRIA3_RAT Gria3 Glutamate receptor 3 8.432e-06 0.37

Suvorexant

OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.494e-181 1.00
OX1R_HUMAN HCRTR1 Orexin receptor type 1 2.027e-169 1.00
OX1R_MOUSE Hcrtr1 Orexin receptor type 1 2.714e-79 1.00
OX2R_MOUSE Hcrtr2 Orexin receptor type 2 2.714e-79 1.00
OX1R_RAT Hcrtr1 Orexin receptor type 1 4.815e-89 0.50
OX2R_RAT Hcrtr2 Orexin receptor type 2 6.186e-85 0.43
PTGES_HUMAN PTGES Prostaglandin E synthase 1.145e-22 0.49
5HT3A_MOUSE Htr3a 5-hydroxytryptamine receptor 3A 4.351e-22 0.40
TRPC6_HUMAN TRPC6 Short transient receptor potential channel 6 3.455e-20 0.31
TRPC3_HUMAN TRPC3 Short transient receptor potential channel 3 3.099e-18 0.31
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 2.961e-17 0.36
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 2.22e-16 0.31
Q9GSG8_AEDAE Ultraspiracle isoform-A 1.998e-15 0.29
NPBW1_MOUSE Npbwr1 Neuropeptides B/W receptor type 1 1.676e-14 0.36
MC4R_HUMAN MC4R Melanocortin receptor 4 1.821e-11 0.33
P2RX7_RAT P2rx7 P2X purinoceptor 7 5.336e-09 0.31
ECR_AEDAE EcR Ecdysone receptor 1.656e-08 0.29
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 4.731e-08 0.31
DHSO_HUMAN SORD Sorbitol dehydrogenase 3.377e-07 0.29
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 7.637e-07 0.32
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.106e-06 0.28
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 6.795e-06 0.35

Ibrutinib

BTK_HUMAN BTK Tyrosine-protein kinase BTK 4.342e-169 1.00
PXL2A_HUMAN PRXL2A Peroxiredoxin-like 2A 2.9e-124 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 4.807e-99 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.426e-59 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.958e-59 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.765e-54 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 7.76e-40 1.00
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.604e-39 1.00
TEC_HUMAN TEC Tyrosine-protein kinase Tec 3.335e-38 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.655e-30 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.163e-27 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.384e-25 1.00
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 1.286e-23 1.00
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 1.259e-22 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 8.423e-20 1.00
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.286e-19 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 4.344e-18 1.00
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.11e-16 1.00
FER_HUMAN FER Tyrosine-protein kinase Fer 2.109e-15 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 2.665e-15 1.00
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 4.785e-14 1.00
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 8.493e-14 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.096e-13 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.994e-12 1.00
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.322e-11 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.588e-06 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.07039 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 0.09123 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 0.2437 1.00
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 2.768e-85 0.41
CDPK4_PLAF7 CPK4 Calcium-dependent protein kinase 4 4.311e-61 0.34
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 2.866e-50 0.50
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 9.778e-47 0.50
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 1.474e-46 0.46
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.464e-45 0.50
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.644e-42 0.36
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 8.239e-40 0.37
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.85e-39 0.46
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.776e-37 0.59
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 3.119e-36 0.46
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 4.974e-32 0.35
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 1.114e-26 0.42
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5.338e-18 0.46
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 3.331e-16 0.46
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 8.216e-15 0.59
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 6.373e-14 0.42
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 1.619e-12 0.42
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 3.529e-12 0.42
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 2.285e-11 0.39
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 2.088e-10 0.42
INSR_HUMAN INSR Insulin receptor 2.489e-10 0.64
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 3.297e-10 0.42
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 3.579e-10 0.42
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 8.192e-10 0.42
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 9.7e-10 0.74
LIMK1_HUMAN LIMK1 LIM domain kinase 1 1.464e-09 0.42
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 1.934e-09 0.33
INSR_MOUSE Insr Insulin receptor 1.364e-08 0.32
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 1.889e-08 0.42
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 4.208e-08 0.42
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 6.28e-08 0.33
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 6.584e-08 0.42
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 6.799e-08 0.29
ACVR1_HUMAN ACVR1 Activin receptor type-1 1.092e-07 0.41
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.895e-07 0.29
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 3.061e-07 0.42
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 4.659e-07 0.33
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 6.427e-07 0.41
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 7.281e-07 0.42
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 8.704e-07 0.42
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 1.03e-06 0.42
MK12_HUMAN MAPK12 Mitogen-activated protein kinase 12 1.172e-06 0.42
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 1.406e-06 0.42
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.482e-06 0.29
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.284e-06 0.31
FRK_HUMAN FRK Tyrosine-protein kinase FRK 2.828e-06 0.42
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 3.3e-06 0.41
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 4.256e-06 0.29
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 4.414e-06 0.30
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.786e-06 0.41
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 5.278e-06 0.42
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 5.619e-06 0.41
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 8.509e-06 0.42

Tetracaine

CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 5.976e-142 1.00
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 6.843e-21 1.00
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 2.387e-14 1.00
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 1.06e-08 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.001234 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.007792 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.1146 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.5423 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.9968 1.00
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 0.9999 1.00
ACRO_HUMAN ACR Acrosin 7.022e-55 0.42
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 8.062e-48 0.32
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 9.185e-43 0.33
DYN2_HUMAN DNM2 Dynamin-2 3.436e-40 0.33
ERG1_RAT Sqle Squalene monooxygenase 1.816e-38 0.37
TLR1_HUMAN TLR1 Toll-like receptor 1 1.377e-35 0.28
THA_HUMAN THRA Thyroid hormone receptor alpha 1.471e-33 0.43
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.296e-31 0.30
THB_HUMAN THRB Thyroid hormone receptor beta 7.111e-30 0.40
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.644e-26 0.30
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.898e-25 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.898e-25 0.29
SENP1_HUMAN SENP1 Sentrin-specific protease 1 3.143e-23 0.30
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 8.889e-23 0.32
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 6.033e-21 0.37
SMO_MOUSE Smo Smoothened homolog 2.111e-19 0.41
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 6.569e-18 0.31
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.521e-17 0.30
DHPS_ECOLI folP Dihydropteroate synthase 1.11e-16 0.40
PPARA_RAT Ppara Peroxisome proliferator-activated receptor alpha 1.11e-16 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 7.772e-16 0.32
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.11e-15 0.30
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 4.441e-15 0.29
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 5.329e-15 0.59
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.577e-14 0.32
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.577e-14 0.32
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.032e-14 0.29
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 4.43e-14 0.31
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.094e-13 0.32
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 4.884e-12 0.38
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 5.371e-12 0.38
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 9.16e-12 0.36
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 7.998e-11 0.30
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.237e-10 0.30
Q4Q5W4_LEIMA Putative squalene synthase 3.022e-10 0.30
PHLC_BACCE plc Phospholipase C 7.541e-10 0.29
DYR_ENTFC folA Dihydrofolate reductase 9.85e-10 0.28
DYN1_HUMAN DNM1 Dynamin-1 1.675e-09 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.055e-09 0.38
UR2R_HUMAN UTS2R Urotensin-2 receptor 5.007e-09 0.33
RIR2_HUMAN RRM2 Ribonucleoside-diphosphate reductase subunit M2 7.167e-09 0.33
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.035e-08 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 1.036e-08 0.30
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.081e-08 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.309e-08 0.32
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.905e-08 0.33
TRY1_HUMAN PRSS1 Trypsin-1 2.056e-08 0.42
STS_HUMAN STS Steryl-sulfatase 2.823e-08 0.42
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.67e-08 0.32
TYTR_TRYBB TPR Trypanothione reductase 4.115e-08 0.47
TLR7_MOUSE Tlr7 Toll-like receptor 7 5.548e-08 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 9.114e-08 0.40
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.446e-07 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.696e-07 0.29
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 2.363e-07 0.31
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.426e-07 0.41
O61059_LEIME LmGT2 Glucose transporter 3.797e-07 0.40
DPOL_VACCW POL DNA polymerase 4.049e-07 0.35
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 5.928e-07 0.29
CEL_BOVIN CEL Bile salt-activated lipase 6.322e-07 0.28
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 6.572e-07 0.29
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 8.256e-07 0.35
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 8.783e-07 0.30
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 9.743e-07 0.37
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 9.838e-07 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.52e-06 0.31
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.618e-06 0.29
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 2.044e-06 0.32
TLR7_HUMAN TLR7 Toll-like receptor 7 2.226e-06 0.35
NORA_STAAU norA Quinolone resistance protein NorA 2.257e-06 0.31
O97467_PLAFA ht1 Hexose transporter 1 2.329e-06 0.40
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.771e-06 0.30
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.878e-06 0.43
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 4.796e-06 0.40
ECR_BOMMO EcR Ecdysone receptor 5.821e-06 0.32
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 9.56e-06 0.39
CAH1_HUMAN CA1 Carbonic anhydrase 1 9.948e-06 0.43

Idelalisib

PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 8.673e-128 1.00
P85B_HUMAN PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta 2.9e-124 1.00
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 2.133e-91 1.00
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 6.323e-66 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.378e-61 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 6.439e-15 1.00
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 1.679e-09 1.00
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 0.1742 1.00
AHK3_ARATH AHK3 Histidine kinase 3 1.445e-31 0.32
SHH_MOUSE Shh Sonic hedgehog protein 4.045e-29 0.33
CHIT_YEAST CTS1 Endochitinase 6.442e-26 0.32
CKX2_ARATH CKX2 Cytokinin dehydrogenase 2 5.641e-13 0.28
GPR39_HUMAN GPR39 G-protein coupled receptor 39 1.032e-12 0.32
AHK4_ARATH AHK4 Histidine kinase 4 2.443e-12 0.30
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.223e-09 0.32
MTAP2_HUMAN MAP2 Microtubule-associated protein 2 3.448e-07 0.33
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 6.56e-07 0.36

Ivabradine

HCN2_MOUSE Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 4.534e-117 1.00
HCN1_MOUSE Hcn1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 1.625e-83 1.00
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 5.983e-38 1.00
MDM4_HUMAN MDM4 Protein Mdm4 5.229e-37 0.32
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.498e-27 0.37
MDM2_CANLF MDM2 E3 ubiquitin-protein ligase Mdm2 6.795e-26 0.32
MDM2_MOUSE Mdm2 E3 ubiquitin-protein ligase Mdm2 6.795e-26 0.32
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.554e-24 0.32
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 7.983e-23 0.34
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 1.11e-16 0.32
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 2.22e-16 0.32
ACES_MOUSE Ache Acetylcholinesterase 9.992e-16 0.32
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.332e-15 0.32
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.443e-15 0.30
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.887e-15 0.30
MDM2_HUMAN MDM2 E3 ubiquitin-protein ligase Mdm2 3.553e-15 0.32
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.044e-14 0.36
ACES_RAT Ache Acetylcholinesterase 1.232e-14 0.33
DRD1_PIG DRD1 D(1A) dopamine receptor 5.951e-14 0.34
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 8.593e-14 0.30
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.279e-12 0.37
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 3.168e-12 0.39
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.659e-10 0.30
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 3.031e-10 0.39
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 9.098e-10 0.32
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 6.034e-09 0.30
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.035e-08 0.32
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.385e-08 0.36
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 2.187e-08 0.30
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 6.486e-08 0.33
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.316e-07 0.43
DRD1_RAT Drd1 D(1A) dopamine receptor 2.047e-07 0.33
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 2.694e-07 0.39
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.236e-07 0.32
ACES_HUMAN ACHE Acetylcholinesterase 5.994e-07 0.33
MAP1_ECOLI map Methionine aminopeptidase 8.488e-07 0.41
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.32e-06 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.319e-06 0.33

Vilanterol

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 3.889e-104 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.606e-83 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.004e-82 1.00
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.559e-50 0.30
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.253e-40 0.37
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 3.165e-40 0.68
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 7.403e-21 0.36
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 2.378e-19 0.43
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.196e-18 0.68
G3HDX1_CRIGR Alpha-1B adrenergic receptor 8.882e-16 0.30
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 1.73e-11 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.221e-11 0.45
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 6.296e-08 0.30
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.43e-07 0.31
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.279e-06 0.31
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.123e-06 0.29
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 7.272e-06 0.53

Atosiban

V1BR_HUMAN AVPR1B Vasopressin V1b receptor 9.444e-78 1.00
OXYR_HUMAN OXTR Oxytocin receptor 1.718e-65 1.00
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 1.288e-44 1.00
V2R_HUMAN AVPR2 Vasopressin V2 receptor 1.179e-42 1.00
OXYR_RAT Oxtr Oxytocin receptor 1.373e-26 1.00
V2R_PIG AVPR2 Vasopressin V2 receptor 5.848e-162 0.60
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 3.703e-109 0.34
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 7.819e-91 0.34
V2R_BOVIN AVPR2 Vasopressin V2 receptor 1.574e-90 0.62
NTR1_RAT Ntsr1 Neurotensin receptor type 1 1.269e-89 0.34
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 6.911e-87 0.33
Q5D7U5_CHICK OXTR Oxytocin-like receptor 1.149e-70 0.57
SORT_HUMAN SORT1 Sortilin 5.225e-60 0.33
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 2.048e-59 0.32
SSR5_RAT Sstr5 Somatostatin receptor type 5 6.78e-57 0.33
HDAC5_MOUSE Hdac5 Histone deacetylase 5 8.275e-57 0.34
F1SH20_PIG TRHDE Uncharacterized protein 7.405e-53 0.34
HDAC8_MOUSE Hdac8 Histone deacetylase 8 7.361e-49 0.33
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 3.749e-48 0.29
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.337e-46 0.36
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 2.614e-40 0.32
OXYR_MOUSE Oxtr Oxytocin receptor 4.131e-40 0.65
GALR1_RAT Galr1 Galanin receptor type 1 1.184e-38 0.31
GALR2_RAT Galr2 Galanin receptor type 2 1.184e-38 0.31
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.783e-37 0.31
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 8.638e-34 0.43
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 4.157e-33 0.35
A4HSF7_LEIIN TRYR Trypanothione reductase 4.903e-28 0.35
V1AR_RAT Avpr1a Vasopressin V1a receptor 2.076e-26 0.74
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 3.169e-24 0.30
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 5.699e-24 0.34
NRP1_RAT Nrp1 Neuropilin-1 5.865e-23 0.29
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 2.906e-22 0.36
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.189e-19 0.30
V1BR_RAT Avpr1b Vasopressin V1b receptor 6.983e-19 0.67
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.02e-18 0.30
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 3.291e-17 0.33
O07911_STAAU agrC AgrC 1.887e-15 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.887e-15 0.29
HDAC6_MOUSE Hdac6 Histone deacetylase 6 2.554e-15 0.34
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.343e-14 0.31
V2R_RAT Avpr2 Vasopressin V2 receptor 1.599e-14 0.69
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 3.12e-14 0.33
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 3.697e-14 0.36
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 7.438e-14 0.33
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.469e-13 0.33
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 4.156e-13 0.30
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 6.108e-13 0.28
TRFR_RAT Trhr Thyrotropin-releasing hormone receptor 6.449e-13 0.28
ITA3_HUMAN ITGA3 Integrin alpha-3 7.764e-13 0.32
HDAC1_MOUSE Hdac1 Histone deacetylase 1 9.642e-13 0.34
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 2.765e-12 0.35
UR2R_RAT Uts2r Urotensin-2 receptor 6.77e-12 0.32
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 1.577e-10 0.28
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 2.131e-10 0.30
PRTN3_HUMAN PRTN3 Myeloblastin 3.232e-10 0.30
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.01e-09 0.35
TRY1_BOVIN Cationic trypsin 1.673e-09 0.30
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.406e-09 0.29
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 4.864e-09 0.28
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.088e-08 0.32
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.193e-08 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 4.058e-08 0.35
OPRM_RAT Oprm1 Mu-type opioid receptor 6.556e-08 0.35
OPRD_RAT Oprd1 Delta-type opioid receptor 1.064e-07 0.35
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.199e-07 0.32
Q9R297_RAT Mlnr Motilin receptor 2.838e-07 0.28
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.599e-07 0.35
MC3R_MOUSE Mc3r Melanocortin receptor 3 5.813e-07 0.31
NK1R_CAVPO TACR1 Substance-P receptor 1.015e-06 0.31
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.273e-06 0.39
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.74e-06 0.33
ACE_HUMAN ACE Angiotensin-converting enzyme 1.805e-06 0.35
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.931e-06 0.28
LGMN_HUMAN LGMN Legumain 2.018e-06 0.31
THRB_HUMAN F2 Prothrombin 2.499e-06 0.31
NK2R_RAT Tacr2 Substance-K receptor 3.81e-06 0.30
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 4.365e-06 0.33
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 4.632e-06 0.31
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 6.573e-06 0.31
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 9.962e-06 0.33

Lenvatinib

VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.781e-60 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 6.739e-14 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 9.845e-09 1.00
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 2.918e-73 0.44
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 9.251e-69 0.35
MET_HUMAN MET Hepatocyte growth factor receptor 3.001e-56 0.59
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.682e-53 0.59
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 3.543e-39 0.31
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.187e-35 0.47
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 5.287e-33 0.32
PYGL_RAT Pygl Glycogen phosphorylase, liver form 2.647e-30 0.32
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 2.21e-28 0.35
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.704e-25 0.30
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.747e-24 0.47
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.919e-23 0.66
NTR2_RAT Ntsr2 Neurotensin receptor type 2 8.129e-22 0.30
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 3.426e-21 0.30
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 4.661e-21 0.35
FAK1_HUMAN PTK2 Focal adhesion kinase 1 6.656e-20 0.38
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 1.575e-19 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.093e-19 0.35
EGFR_HUMAN EGFR Epidermal growth factor receptor 4.234e-19 0.47
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.466e-19 0.35
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.512e-18 0.47
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 4.037e-18 0.44
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 7.855e-18 0.31
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.202e-17 0.47
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.505e-17 0.32
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.11e-16 0.35
DRD3_RAT Drd3 D(3) dopamine receptor 1.11e-16 0.34
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 4.441e-16 0.59
TTK_HUMAN TTK Dual specificity protein kinase TTK 6.661e-16 0.35
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 7.772e-16 0.47
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.22e-15 0.38
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.219e-15 0.55
LCK_HUMAN LCK Tyrosine-protein kinase Lck 5.329e-15 0.55
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 5.662e-15 0.58
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 7.438e-15 0.35
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.288e-14 0.47
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 1.676e-14 0.32
MYO3B_HUMAN MYO3B Myosin-IIIb 2.109e-14 0.30
CRFR2_HUMAN CRHR2 Corticotropin-releasing factor receptor 2 2.565e-14 0.32
MET_MOUSE Met Hepatocyte growth factor receptor 2.753e-14 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 3.353e-14 0.59
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 3.708e-14 0.47
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 4.619e-14 0.34
RON_HUMAN MST1R Macrophage-stimulating protein receptor 5.573e-14 0.47
MK12_HUMAN MAPK12 Mitogen-activated protein kinase 12 5.906e-14 0.30
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 8.626e-14 0.47
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.183e-13 0.36
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.512e-13 0.31
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.648e-13 0.47
DRD1_BOVIN DRD1 D(1A) dopamine receptor 4.424e-13 0.34
AURKB_HUMAN AURKB Aurora kinase B 5.711e-13 0.66
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 1.106e-12 0.50
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.182e-12 0.30
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.283e-12 0.31
AURKA_HUMAN AURKA Aurora kinase A 1.33e-12 0.66
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 4.363e-12 0.32
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 5.083e-12 0.35
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 6.727e-12 0.47
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 7.413e-12 0.31
ABCBB_RAT Abcb11 Bile salt export pump 9.7e-12 0.29
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 9.75e-12 0.47
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 1.155e-11 0.38
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 1.786e-11 0.47
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 2.25e-11 0.30
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 4.178e-11 0.47
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 5.1e-11 0.30
CSK_HUMAN CSK Tyrosine-protein kinase CSK 7.066e-11 0.47
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 7.971e-11 0.47
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 9.14e-11 0.49
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.084e-10 0.30
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.46e-10 0.47
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.696e-10 0.47
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 1.807e-10 0.31
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.707e-10 0.47
GYRB_MYCSM gyrB DNA gyrase subunit B 2.951e-10 0.34
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 3.071e-10 0.35
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 4.156e-10 0.30
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 4.156e-10 0.30
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 7.281e-10 0.47
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 7.592e-10 0.30
Q9JLY8_RAT Ccr1 C-C motif chemokine receptor 1 9.346e-10 0.33
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 1.675e-09 0.30
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.258e-09 0.30
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 3.703e-09 0.30
DRD2_RAT Drd2 D(2) dopamine receptor 4.214e-09 0.33
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 4.925e-09 0.30
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 5.9e-09 0.30
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 5.9e-09 0.30
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 6.257e-09 0.47
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 6.431e-09 0.35
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 7.542e-09 0.47
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 8.464e-09 0.31
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 9.154e-09 0.30
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.322e-08 0.29
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.873e-08 0.38
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 2.038e-08 0.30
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 2.054e-08 0.30
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.088e-08 0.34
HCK_HUMAN HCK Tyrosine-protein kinase HCK 3.089e-08 0.47
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 3.693e-08 0.36
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 4.252e-08 0.30
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 5.471e-08 0.30
MYO3A_HUMAN MYO3A Myosin-IIIa 5.471e-08 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 5.915e-08 0.29
CTRO_HUMAN CIT Citron Rho-interacting kinase 5.958e-08 0.30
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 5.958e-08 0.30
FA10_BOVIN F10 Coagulation factor X 6.685e-08 0.29
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 8.218e-08 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.031e-07 0.29
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 1.105e-07 0.47
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.117e-07 0.30
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.295e-07 0.30
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.295e-07 0.30
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 1.295e-07 0.30
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.295e-07 0.30
AURKC_HUMAN AURKC Aurora kinase C 1.335e-07 0.47
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.498e-07 0.30
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.581e-07 0.33
CRFR1_HUMAN CRHR1 Corticotropin-releasing factor receptor 1 1.594e-07 0.33
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.64e-07 0.47
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 3.357e-07 0.30
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 3.357e-07 0.30
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 5.435e-07 0.30
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 5.668e-07 0.32
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 7.268e-07 0.47
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 7.424e-07 0.31
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 7.628e-07 0.35
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 7.809e-07 0.55
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 9.34e-07 0.32
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 9.958e-07 0.30
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.582e-06 0.35
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.72e-06 0.30
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 1.967e-06 0.47
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 2.464e-06 0.44
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.657e-06 0.47
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.827e-06 0.30
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.917e-06 0.30
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.181e-06 0.30
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.272e-06 0.30
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 3.497e-06 0.31
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 3.712e-06 0.47
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 4.306e-06 0.47
INSRR_HUMAN INSRR Insulin receptor-related protein 4.449e-06 0.30
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 4.449e-06 0.30
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 4.829e-06 0.33
AGP1_YEAST AGP1 General amino acid permease AGP1 6.086e-06 0.29
ALK_HUMAN ALK ALK tyrosine kinase receptor 6.369e-06 0.32
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 6.746e-06 0.30
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 7.19e-06 0.47
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 8.318e-06 0.30
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 8.385e-06 0.47
CDK3_HUMAN CDK3 Cyclin-dependent kinase 3 8.73e-06 0.29
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 9.81e-06 0.32
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.9e-06 0.30

Edoxaban

FA10_HUMAN F10 Coagulation factor X 1.758e-48 1.00
FA10_RAT F10 Coagulation factor X 1.283e-26 0.67
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.22e-16 0.33
DPP4_PIG DPP4 Dipeptidyl peptidase 4 3.851e-09 0.32
FA10_RABIT F10 Coagulation factor X 6.39e-06 0.67

Olodaterol

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.326e-46 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.737e-41 1.00
CASR_HUMAN CASR Extracellular calcium-sensing receptor 8.219e-65 0.44
CASR_BOVIN CASR Extracellular calcium-sensing receptor 3.56e-37 0.29
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.467e-28 0.40
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 7.504e-26 0.39
CASR_RAT Casr Extracellular calcium-sensing receptor 3.397e-14 0.31
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 9.082e-10 0.35
CALM1_HUMAN CALM1 Calmodulin-1 6.072e-09 0.32
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 8.445e-09 0.34
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 4.609e-08 0.30
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.046e-07 0.30

Vortioxetine

5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 8.33e-44 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.533e-21 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.639e-18 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.229e-14 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 3.796e-08 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.368e-08 1.00
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.822e-07 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 6.266e-07 1.00
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 6.655e-05 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.0001759 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0007031 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 0.000851 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.002212 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 0.00255 1.00
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 0.03102 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 0.07663 1.00
SOS1_HUMAN SOS1 Son of sevenless homolog 1 1.475e-20 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 3.331e-16 0.32
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.997e-15 0.54
KHK_HUMAN KHK Ketohexokinase 4.174e-10 0.36
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.41e-09 0.32
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 2.644e-09 0.41
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 6.784e-09 0.54
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.021e-08 0.34
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 3.282e-07 0.32
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 3.834e-07 0.37
ITB2_HUMAN ITGB2 Integrin beta-2 1.488e-06 0.30

Nintedanib

PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 4.675e-43 1.00
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 6.254e-38 1.00
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 2.971e-37 1.00
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 2.97e-32 1.00
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 3.937e-30 1.00
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 4.419e-25 1.00
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 4.419e-25 1.00
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 4.419e-25 1.00
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 4.419e-25 1.00
MYO3B_HUMAN MYO3B Myosin-IIIb 7.773e-24 1.00
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 9.712e-23 1.00
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 9.712e-23 1.00
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 9.712e-23 1.00
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 9.163e-22 1.00
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 6.843e-21 1.00
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 6.843e-21 1.00
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 7.269e-21 1.00
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 7.522e-21 1.00
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 4.197e-20 1.00
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 4.197e-20 1.00
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 4.197e-20 1.00
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 4.197e-20 1.00
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.176e-19 1.00
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 9.774e-19 1.00
INSRR_HUMAN INSRR Insulin receptor-related protein 9.774e-19 1.00
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 9.774e-19 1.00
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 9.774e-19 1.00
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 3.874e-18 1.00
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 3.874e-18 1.00
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 3.874e-18 1.00
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.377e-17 1.00
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.377e-17 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.917e-17 1.00
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 4.449e-17 1.00
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 4.449e-17 1.00
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 4.449e-17 1.00
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 4.449e-17 1.00
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 1.11e-16 1.00
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.11e-16 1.00
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 1.11e-16 1.00
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 3.331e-16 1.00
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 3.331e-16 1.00
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 3.331e-16 1.00
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 3.331e-16 1.00
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 8.882e-16 1.00
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 8.882e-16 1.00
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 2.22e-15 1.00
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 2.22e-15 1.00
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.22e-15 1.00
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 5.218e-15 1.00
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 5.218e-15 1.00
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 5.218e-15 1.00
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1.144e-14 1.00
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.144e-14 1.00
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 1.144e-14 1.00
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.144e-14 1.00
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 1.144e-14 1.00
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.887e-14 1.00
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 2.387e-14 1.00
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.387e-14 1.00
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 2.387e-14 1.00
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 2.387e-14 1.00
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 5.684e-14 1.00
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 9.259e-14 1.00
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 9.259e-14 1.00
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 9.259e-14 1.00
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 9.259e-14 1.00
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 1.731e-13 1.00
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 3.137e-13 1.00
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 3.137e-13 1.00
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 5.523e-13 1.00
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 5.523e-13 1.00
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 5.523e-13 1.00
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 5.523e-13 1.00
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 9.469e-13 1.00
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 9.469e-13 1.00
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.063e-12 1.00
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 1.584e-12 1.00
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.584e-12 1.00
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.584e-12 1.00
ACV1B_HUMAN ACVR1B Activin receptor type-1B 2.589e-12 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.589e-12 1.00
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.589e-12 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.485e-12 1.00
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.001e-11 1.00
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 1.001e-11 1.00
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.295e-11 1.00
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 3.307e-11 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.307e-11 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.698e-11 1.00
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 6.82e-11 1.00
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 8.35e-11 1.00
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 9.605e-11 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.839e-10 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 3.375e-10 1.00
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 4.504e-10 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 4.504e-10 1.00
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 1.425e-09 1.00
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 2.136e-09 1.00
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 2.698e-09 1.00
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 3.121e-09 1.00
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 3.385e-09 1.00
AURKC_HUMAN AURKC Aurora kinase C 4.564e-09 1.00
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 4.779e-09 1.00
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 1.415e-08 1.00
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 2.882e-08 1.00
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 2.882e-08 1.00
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 2.882e-08 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.014e-08 1.00
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 4.875e-08 1.00
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 8.639e-08 1.00
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.318e-07 1.00
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 1.939e-07 1.00
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 2.227e-07 1.00
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 2.851e-07 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.733e-07 1.00
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 4.287e-07 1.00
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 5.09e-07 1.00
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 5.68e-07 1.00
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 8.647e-07 1.00
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 1.164e-06 1.00
ACVR1_HUMAN ACVR1 Activin receptor type-1 5.711e-06 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 6.796e-06 1.00
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 8.819e-06 1.00
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 9.132e-06 1.00
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 9.927e-06 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.363e-05 1.00
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.449e-05 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.54e-05 1.00
YES_HUMAN YES1 Tyrosine-protein kinase Yes 2.06e-05 1.00
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 2.408e-05 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.433e-05 1.00
FER_HUMAN FER Tyrosine-protein kinase Fer 3.343e-05 1.00
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 3.517e-05 1.00
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 5.141e-05 1.00
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 5.184e-05 1.00
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 6.503e-05 1.00
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 6.544e-05 1.00
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 0.000139 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 0.0001736 1.00
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 0.0001928 1.00
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 0.000323 1.00
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 0.0003531 1.00
AURKB_HUMAN AURKB Aurora kinase B 0.0004261 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 0.0004316 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 0.0004758 1.00
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 0.0005911 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 0.0005951 1.00
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 0.0007349 1.00
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 0.0008578 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 0.0009121 1.00
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 0.001221 1.00
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 0.001279 1.00
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 0.001381 1.00
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 0.001952 1.00
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 0.002098 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.002107 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 0.002331 1.00
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 0.002352 1.00
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 0.002412 1.00
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 0.002454 1.00
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 0.002625 1.00
FAK1_HUMAN PTK2 Focal adhesion kinase 1 0.002732 1.00
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 0.002919 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 0.003011 1.00
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 0.00345 1.00
WEE1_HUMAN WEE1 Wee1-like protein kinase 0.003549 1.00
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.003648 1.00
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 0.003813 1.00
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.004026 1.00
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 0.004418 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 0.005038 1.00
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 0.005533 1.00
MINK1_HUMAN MINK1 Misshapen-like kinase 1 0.005635 1.00
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 0.006479 1.00
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 0.00664 1.00
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 0.006888 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 0.007401 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 0.008404 1.00
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 0.008499 1.00
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 0.008831 1.00
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 0.01012 1.00
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 0.01012 1.00
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 0.01472 1.00
MET_HUMAN MET Hepatocyte growth factor receptor 0.02136 1.00
BTK_HUMAN BTK Tyrosine-protein kinase BTK 0.022 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 0.02359 1.00
TIE2_HUMAN TEK Angiopoietin-1 receptor 0.02531 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 0.02729 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 0.02807 1.00
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 0.03202 1.00
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 0.03813 1.00
ALK_HUMAN ALK ALK tyrosine kinase receptor 0.03951 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 0.0511 1.00
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 0.05133 1.00
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 0.05689 1.00
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 0.05918 1.00
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 0.06162 1.00
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 0.06602 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 0.06905 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 0.08484 1.00
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 0.09366 1.00
KPCT_HUMAN PRKCQ Protein kinase C theta type 0.1078 1.00
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 0.1177 1.00
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 0.1218 1.00
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 0.1316 1.00
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 0.1329 1.00
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 0.1563 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 0.1622 1.00
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 0.1798 1.00
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 0.1831 1.00
TTK_HUMAN TTK Dual specificity protein kinase TTK 0.1917 1.00
INSR_HUMAN INSR Insulin receptor 0.1943 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 0.2503 1.00
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 0.389 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 0.3972 1.00
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 0.5673 1.00
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 0.5842 1.00
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 0.6106 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.6665 1.00
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 0.7271 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 0.8045 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 0.8803 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 0.9948 1.00
AUKBB_XENLA aurkb-b Aurora kinase B-B 4.627e-102 0.50
KC1A_PIG CSNK1A1 Casein kinase I isoform alpha 3.42e-28 0.34
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.95e-26 0.43
MK09_MOUSE Mapk9 Mitogen-activated protein kinase 9 7.192e-24 0.30
RET_MOUSE Ret Proto-oncogene tyrosine-protein kinase receptor Ret 7.192e-24 0.30
ROS1_MOUSE Ros1 Proto-oncogene tyrosine-protein kinase ROS 7.192e-24 0.30
TIE1_MOUSE Tie1 Tyrosine-protein kinase receptor Tie-1 7.192e-24 0.30
MRGX2_HUMAN MRGPRX2 Mas-related G-protein coupled receptor member X2 3.089e-23 0.30
FLT3_MOUSE Flt3 Receptor-type tyrosine-protein kinase FLT3 1.191e-21 0.30
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 6.709e-20 0.30
LIMK2_HUMAN LIMK2 LIM domain kinase 2 7.924e-19 0.33
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 9.056e-18 0.28
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 1.11e-16 0.32
FGR_MOUSE Fgr Tyrosine-protein kinase Fgr 5.551e-16 0.30
ZAP70_MOUSE Zap70 Tyrosine-protein kinase ZAP-70 1.11e-15 0.30
EPHB2_MOUSE Ephb2 Ephrin type-B receptor 2 5.929e-14 0.30
BMX_MOUSE Bmx Cytoplasmic tyrosine-protein kinase BMX 1.15e-13 0.30
LYN_MOUSE Lyn Tyrosine-protein kinase Lyn 1.15e-13 0.30
MET_MOUSE Met Hepatocyte growth factor receptor 1.15e-13 0.30
RON_MOUSE Mst1r Macrophage-stimulating protein receptor 1.15e-13 0.30
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 2.593e-13 0.32
ALK_MOUSE Alk ALK tyrosine kinase receptor 1.812e-12 0.30
EPHA3_MOUSE Epha3 Ephrin type-A receptor 3 1.812e-12 0.30
PRIO_SHEEP PRNP Major prion protein 2.417e-12 0.30
B2LUN4_PIG GSK3-beta Glycogen synthase kinase 3 beta 2.813e-12 0.33
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.905e-10 0.41
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.988e-09 0.35
LIMK1_HUMAN LIMK1 LIM domain kinase 1 2.929e-09 0.33
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.083e-08 0.38
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 1.145e-08 0.43
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.84e-08 0.33
CCKAR_RAT Cckar Cholecystokinin receptor type A 4.29e-08 0.38
INSR_MOUSE Insr Insulin receptor 5.159e-08 0.30
VGFR1_MOUSE Flt1 Vascular endothelial growth factor receptor 1 1.094e-07 0.30
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 2.507e-07 0.30
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.587e-07 0.38
ACRO_HUMAN ACR Acrosin 4.785e-07 0.33
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 7.538e-07 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.084e-06 0.34
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 2.957e-06 0.28
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 3.982e-06 0.36
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.389e-06 0.30
V2R_RAT Avpr2 Vasopressin V2 receptor 6.013e-06 0.33
WDR5_HUMAN WDR5 WD repeat-containing protein 5 6.887e-06 0.32
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 9.991e-06 0.29

Elvitegravir

Q76353_9HIV1 Integrase 6.267e-37 1.00
Q7ZJM1_9HIV1 pol Integrase 8.698e-07 1.00
CFAD_HUMAN CFD Complement factor D 9.789e-38 0.33
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 4.441e-16 0.41
T1QYY3_9HIV1 int Integrase 2.083e-11 0.31
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.035e-07 0.32
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.967e-06 0.28
FA11_HUMAN F11 Coagulation factor XI 3.39e-06 0.31

Netupitant

NK1R_HUMAN TACR1 Substance-P receptor 1.133e-35 1.00
ERMA_STAAN ermA1; ermA2; ermA3; ermA4; ermA5 rRNA adenine N-6-methyltransferase 3.514e-46 0.30
SMO_HUMAN SMO Smoothened homolog 2.354e-39 0.37
NK3R_HUMAN TACR3 Neuromedin-K receptor 1.585e-31 0.67
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 8.897e-26 0.35
NK1R_CAVPO TACR1 Substance-P receptor 1.03e-19 0.36
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 6.351e-19 0.31
SMO_MOUSE Smo Smoothened homolog 5.414e-17 0.34
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.998e-15 0.34
ZAP70_MOUSE Zap70 Tyrosine-protein kinase ZAP-70 4.441e-15 0.29
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.732e-14 0.31
BMX_MOUSE Bmx Cytoplasmic tyrosine-protein kinase BMX 3.922e-13 0.29
LYN_MOUSE Lyn Tyrosine-protein kinase Lyn 3.922e-13 0.29
MET_MOUSE Met Hepatocyte growth factor receptor 3.922e-13 0.29
RON_MOUSE Mst1r Macrophage-stimulating protein receptor 3.922e-13 0.29
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.862e-12 0.33
MET_HUMAN MET Hepatocyte growth factor receptor 2.883e-12 0.42
MK09_MOUSE Mapk9 Mitogen-activated protein kinase 9 9.7e-12 0.29
RET_MOUSE Ret Proto-oncogene tyrosine-protein kinase receptor Ret 9.7e-12 0.29
ROS1_MOUSE Ros1 Proto-oncogene tyrosine-protein kinase ROS 9.7e-12 0.29
TIE1_MOUSE Tie1 Tyrosine-protein kinase receptor Tie-1 9.7e-12 0.29
FLT3_MOUSE Flt3 Receptor-type tyrosine-protein kinase FLT3 1.105e-10 0.29
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 1.304e-10 0.32
IP3KB_HUMAN ITPKB Inositol-trisphosphate 3-kinase B 2.902e-10 0.31
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 7.541e-10 0.29
HRH4_HUMAN HRH4 Histamine H4 receptor 9.787e-09 0.33
HCK_HUMAN HCK Tyrosine-protein kinase HCK 4.647e-08 0.34
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 4.957e-08 0.34
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 7.799e-08 0.29
INSR_MOUSE Insr Insulin receptor 1.031e-07 0.29
AOC3_RAT Aoc3 Membrane primary amine oxidase 1.423e-07 0.31
WNT3A_MOUSE Wnt3a Protein Wnt-3a 1.452e-07 0.29
LCK_HUMAN LCK Tyrosine-protein kinase Lck 4.592e-07 0.34
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.777e-06 0.30
B2RXC2_MOUSE Itpkb Kinase 1.941e-06 0.31
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 2.591e-06 0.31
HRH1_RAT Hrh1 Histamine H1 receptor 3.393e-06 0.33
SSR1_RAT Sstr1 Somatostatin receptor type 1 3.646e-06 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 4.705e-06 0.31

Fendiline

CALM_BOVIN CALM Calmodulin 2.191e-35 1.00
CASR_HUMAN CASR Extracellular calcium-sensing receptor 5.799e-25 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.51e-07 1.00
GPR55_HUMAN GPR55 G-protein coupled receptor 55 0.0002826 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.06646 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.1688 1.00
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 6.42e-96 0.38
PPAP_HUMAN ACP3 Prostatic acid phosphatase 6.939e-49 0.38
ACER2_HUMAN ACER2 Alkaline ceramidase 2 9.362e-36 0.28
NCS1_HUMAN NCS1 Neuronal calcium sensor 1 9.362e-36 0.28
Q9VWX8_DROME Frq2 FI18190p1 9.362e-36 0.28
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 3.095e-31 0.32
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 5.173e-29 0.28
NEP_MOUSE Mme Neprilysin 1.451e-27 0.31
TYTR_TRYCR TPR Trypanothione reductase 3.684e-24 0.44
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 1.964e-22 0.33
ACE_MOUSE Ace Angiotensin-converting enzyme 6.557e-22 0.33
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 4.636e-21 0.33
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.658e-20 0.46
HRH1_CAVPO HRH1 Histamine H1 receptor 4.94e-20 0.33
MA2B1_HUMAN MAN2B1 Lysosomal alpha-mannosidase 1.193e-19 0.31
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 4.339e-19 0.32
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 7.088e-18 0.28
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 3.331e-16 0.31
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 2.442e-15 0.35
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.121e-14 0.42
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 1.31e-14 0.35
Q63380_RAT NET Transporter 3.486e-14 0.38
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 3.697e-14 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 8.249e-14 0.60
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.471e-13 0.32
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.289e-13 0.42
CALM1_HUMAN CALM1 Calmodulin-1 8.064e-13 0.47
NRP1_RAT Nrp1 Neuropilin-1 2.013e-12 0.30
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 3.82e-12 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 4.656e-12 0.43
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 8.583e-12 0.49
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.043e-11 0.39
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.076e-11 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.376e-11 0.44
US28_HCMVA US28 G-protein coupled receptor homolog US28 6.878e-11 0.29
AMPB_HUMAN RNPEP Aminopeptidase B 1.415e-10 0.28
HRH2_CAVPO HRH2 Histamine H2 receptor 1.638e-10 0.31
LUXR_ALIFS luxR Transcriptional activator protein LuxR 6.882e-10 0.28
HRH1_RAT Hrh1 Histamine H1 receptor 8.34e-10 0.33
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.863e-09 0.30
Q533H1_FELCA UTS2R Urotensin II receptor 2.406e-09 0.29
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.567e-09 0.38
BLAB_AERHY cphA Metallo-beta-lactamase type 2 4.608e-09 0.28
PPO1_AGABI PPO1 Polyphenol oxidase 1 4.608e-09 0.28
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 4.649e-09 0.38
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 5.494e-09 0.31
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.241e-08 0.32
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.804e-08 0.34
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.249e-08 0.40
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.797e-07 0.46
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.962e-07 0.44
KCNH3_HUMAN KCNH3 Potassium voltage-gated channel subfamily H member 3 2.187e-07 0.30
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.267e-07 0.28
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 2.389e-07 0.33
SCAF_HCMVA UL80 Capsid scaffolding protein 3.116e-07 0.30
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 4.268e-07 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.852e-07 0.30
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 6.324e-07 0.42
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 9.396e-07 0.29
HRH1_HUMAN HRH1 Histamine H1 receptor 9.749e-07 0.61
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.006e-06 0.41
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.241e-06 0.30
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.944e-06 0.28
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 4.084e-06 0.29
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 4.194e-06 0.32

Eliglustat

CEGT_HUMAN UGCG Ceramide glucosyltransferase 3.017e-34 1.00
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 2.469e-58 0.38
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.231e-50 0.40
CERT_HUMAN CERT1 Ceramide transfer protein 1.274e-47 0.38
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 6.069e-41 0.33
MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 1.947e-38 0.30
Q6UB75_PIG Group VII phospholipase A2 1.544e-32 0.30
NSMA_HUMAN SMPD2 Sphingomyelin phosphodiesterase 2 3.098e-32 0.40
PPAF_PHAVU Fe(3+)-Zn(2+) purple acid phosphatase 1.239e-26 0.33
DHRS9_RAT Dhrs9 Dehydrogenase/reductase SDR family member 9 1.348e-23 0.29
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.15e-21 0.32
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 3.348e-21 0.29
PIR_HUMAN PIR Pirin 2.362e-19 0.30
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 5.011e-19 0.32
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 2.446e-18 0.29
LUXR_ALIFS luxR Transcriptional activator protein LuxR 2.176e-17 0.32
LASR_PSEAE lasR Transcriptional activator protein LasR 1.11e-16 0.32
G3H407_CRIGR PROKR2 4.441e-16 0.34
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.221e-15 0.34
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 8.349e-14 0.35
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 2.393e-13 0.29
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 2.393e-13 0.29
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 2.393e-13 0.29
ITA3_HUMAN ITGA3 Integrin alpha-3 1.25e-12 0.32
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.68e-12 0.30
TRAR_RHIRD traR Transcriptional activator protein TraR 2.228e-12 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.268e-12 0.32
EDNRB_PIG EDNRB Endothelin receptor type B 1.91e-11 0.31
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 9.172e-11 0.31
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 2.368e-10 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.701e-10 0.30
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 6.452e-10 0.32
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 8.439e-09 0.30
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.844e-08 0.32
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 2.628e-08 0.40
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.228e-08 0.35
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 2.925e-07 0.28
Q9JN24_ECOLX def Peptide deformylase 7.588e-07 0.30
THB_HUMAN THRB Thyroid hormone receptor beta 9.282e-07 0.32
ASAH1_HUMAN ASAH1 Acid ceramidase 1.042e-06 0.44
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 1.166e-06 0.28
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.522e-06 0.29
DYN2_HUMAN DNM2 Dynamin-2 2.561e-06 0.31
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 3.604e-06 0.39
EDNRA_RAT Ednra Endothelin-1 receptor 4.375e-06 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 5.474e-06 0.36
LUCI_AQULA Luciferin 4-monooxygenase 7.112e-06 0.29
ECR_BOMMO EcR Ecdysone receptor 9.682e-06 0.30

Diiodohydroxyquinoline

COMT_RAT Comt Catechol O-methyltransferase 4.265e-33 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 3.422e-23 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.334e-13 1.00
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 3.618e-07 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.001523 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 0.002411 1.00
ACE_RABIT ACE Angiotensin-converting enzyme 0.01758 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 0.5983 1.00
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 0.7112 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9323 1.00
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 0.9551 1.00
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 0.9705 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1 1.00
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.028e-32 0.53
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 4.968e-24 0.43
BXA1_CLOBO botA Botulinum neurotoxin type A 1.468e-22 0.42
BXA1_CLOBH botA Botulinum neurotoxin type A 2.137e-21 0.36
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 2.284e-18 0.34
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 1.312e-17 0.32
AMPX_VIBPR Bacterial leucyl aminopeptidase 6.661e-16 0.39
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.554e-15 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 8.549e-15 0.38
COMT_HUMAN COMT Catechol O-methyltransferase 3.101e-12 0.39
Q7ZJM1_9HIV1 pol Integrase 7.208e-12 0.35
STRP_STRP1 ska Streptokinase A 1.759e-10 0.53
LMP1_EBVB9 LMP1 Latent membrane protein 1 1.789e-10 0.35
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 2.569e-09 0.34
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 3.804e-09 0.38
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.002e-08 0.51
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 3.119e-08 0.42
KLF5_HUMAN KLF5 Krueppel-like factor 5 7.985e-08 0.35
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 3.299e-07 0.38
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 8.737e-07 0.38
VP16_HHV11 Tegument protein VP16 1.516e-06 0.37
PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 3.79e-06 0.34
EGLN1_HUMAN EGLN1 Egl nine homolog 1 7.422e-06 0.31
CAH15_MOUSE Ca15 Carbonic anhydrase 15 7.447e-06 0.72
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 7.962e-06 0.38
I23O1_MOUSE Ido1 Indoleamine 2,3-dioxygenase 1 8.374e-06 0.42

Ciprofibrate

PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 4.691e-32 1.00
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.668e-27 0.51
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 2.276e-26 0.51
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 8.899e-25 0.39
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 3.194e-22 0.42
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 2.065e-19 0.33
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.331e-16 0.36
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 7.772e-16 0.43
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 2.442e-15 0.29
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 1.131e-13 0.30
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 8.631e-10 0.33
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 9.719e-10 0.31
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 7.149e-09 0.30
PPARA_RAT Ppara Peroxisome proliferator-activated receptor alpha 7.566e-09 0.30
Q17SB2_PLAFA Plasmepsin 4 1.305e-07 0.30
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 9.875e-07 0.33

Tibolone

Q690N0_BOVIN PGR Progesterone receptor 5.988e-32 1.00
ANDR_RAT Ar Androgen receptor 1.852e-13 1.00
ESR1_HUMAN ESR1 Estrogen receptor 0.0003919 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.4452 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.6465 1.00
SHBG_HUMAN SHBG Sex hormone-binding globulin 8.226e-51 0.47
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.055e-07 0.29

Umeclidinium

ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.122e-30 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.004e-07 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.573e-06 1.00
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 1.6e-65 0.39
CEGT_HUMAN UGCG Ceramide glucosyltransferase 9.725e-63 0.39
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 1.075e-30 0.39
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 2.805e-19 0.37
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 2.743e-13 0.37
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 3.542e-13 0.37
MURB_STAAU murB UDP-N-acetylenolpyruvoylglucosamine reductase 5.06e-12 0.29
DRD2_MOUSE Drd2 D(2) dopamine receptor 5.414e-11 0.37
UPP1_HUMAN UPP1 Uridine phosphorylase 1 4.084e-10 0.29
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 3.012e-08 0.31
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 8.415e-07 0.29

Trimetazidine

CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 9.163e-22 1.00
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 0.005858 1.00
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 0.04912 1.00
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 0.09982 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.7151 1.00
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 6.286e-76 0.50
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 6.927e-38 0.29
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 6.643e-34 0.37
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 2.127e-26 0.33
DRD1_PIG DRD1 D(1A) dopamine receptor 1.11e-20 0.37
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.22e-16 0.59
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 6.883e-15 0.40
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.299e-14 0.59
Q9JKC1_RAT Bche Carboxylic ester hydrolase 3.919e-12 0.40
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.394e-12 0.37
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.964e-11 0.38
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 2.56e-10 0.38
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.087e-09 0.28
ACVR1_HUMAN ACVR1 Activin receptor type-1 1.042e-08 0.36
ACES_MOUSE Ache Acetylcholinesterase 2.785e-08 0.33
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.015e-08 0.40
DRD3_CHLAE DRD3 D(3) dopamine receptor 5.363e-08 0.28
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.06e-07 0.59
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.496e-07 0.36
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.503e-07 0.40
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 4.789e-07 0.36
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 7.69e-07 0.29
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.148e-07 0.48
ACES_RAT Ache Acetylcholinesterase 9.452e-07 0.31
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.255e-06 0.34
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 1.48e-06 0.30
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 1.54e-06 0.32
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.808e-06 0.40
MTLR_HUMAN MLNR Motilin receptor 1.828e-06 0.33
HRH2_HUMAN HRH2 Histamine H2 receptor 1.944e-06 0.37
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.204e-06 0.40
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.253e-06 0.48
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 3.022e-06 0.33
DPOL_VACCW POL DNA polymerase 3.637e-06 0.30
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.525e-06 0.35
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.445e-06 0.36
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.927e-06 0.36

Cannabidiol

CNR2_MOUSE Cnr2 Cannabinoid receptor 2 1.061e-20 1.00
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.246e-13 1.00
CNR1_RAT Cnr1 Cannabinoid receptor 1 3.636e-13 1.00
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.323e-12 1.00
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 5.303e-12 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
GPR55_HUMAN GPR55 G-protein coupled receptor 55 0.02848 1.00
FAB1_MYCTU kasA 3-oxoacyl-[acyl-carrier-protein] synthase 1 3.875e-36 0.29
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 8.014e-29 0.28
E9PU00_RAT Trpv3 Transient receptor potential cation channel, subfamily V, member 3 3.656e-26 0.32
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.19e-23 0.29
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.05e-20 0.32
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 3.3e-18 0.32
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 5.573e-14 0.34
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 2.343e-13 0.29
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 8.356e-12 0.57
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.305e-07 0.30
DRD1_CARAU D(1) dopamine receptor 4.077e-07 0.31
SPHK2_HUMAN SPHK2 Sphingosine kinase 2 1.029e-06 0.29
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.684e-06 0.57

Avibactam

AMPC_PSEAE ampC Beta-lactamase 6.106e-15 1.00
AMPC_ENTCL ampC Beta-lactamase 2.905e-10 1.00
AMPC_ECOLI ampC Beta-lactamase 2.404e-06 1.00
Q8RL90_PSEAI ampC Beta-lactamase 0 0.68
Q93LQ9_KLEPN KPC-2 Beta-lactamase 0 0.68
Q8RLA6_ACIBA blaOXA-33 Beta-lactamase 1.819e-111 0.58

Fenbufen

PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.701e-09 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 7.151e-09 1.00
VE1_HPV11 E1 Replication protein E1 1.269e-95 0.44
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 1.045e-67 0.58
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.549e-63 0.47
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.724e-59 0.33
EST1_RABIT Liver carboxylesterase 1 1.625e-57 0.48
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 3.235e-49 0.38
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 4.538e-44 0.35
NEP_RAT Mme Neprilysin 1.827e-43 0.44
MMP10_HUMAN MMP10 Stromelysin-2 6.699e-42 0.38
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 5.101e-41 0.42
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 6.444e-41 0.38
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 7.085e-40 0.35
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 9.06e-39 0.45
EST1_HUMAN CES1 Liver carboxylesterase 1 3.558e-38 0.41
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 5.661e-38 0.40
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 3.565e-36 0.34
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 5.95e-36 0.31
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 7.222e-36 0.36
MGLL_RAT Mgll Monoglyceride lipase 2.712e-35 0.33
MMP8_HUMAN MMP8 Neutrophil collagenase 5.067e-34 0.51
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.438e-33 0.44
EST2_HUMAN CES2 Cocaine esterase 7.909e-33 0.41
PA_I34A1 PA Polymerase acidic protein 2.251e-30 0.58
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.22e-29 0.57
GGH_HUMAN GGH Gamma-glutamyl hydrolase 1.476e-29 0.37
LUCI_AQULA Luciferin 4-monooxygenase 7.848e-29 0.35
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.664e-27 0.58
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 2.128e-27 0.44
PRIO_SHEEP PRNP Major prion protein 1.074e-26 0.39
GSHR_PLAF7 GR3 Glutathione reductase 1.401e-26 0.30
NEP_HUMAN MME Neprilysin 2.4e-26 0.39
FEN1_HUMAN FEN1 Flap endonuclease 1 2.978e-26 0.58
LT4R2_HUMAN LTB4R2 Leukotriene B4 receptor 2 5.268e-26 0.30
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 4.179e-25 0.31
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.84e-25 0.33
HDAC1_RAT Hdac1 Histone deacetylase 1 4.045e-23 0.30
PA_I000X PA Polymerase acidic protein 4.358e-21 0.41
MMP2_HUMAN MMP2 72 kDa type IV collagenase 5.521e-21 0.51
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 2.111e-20 0.33
GBRA1_MOUSE Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 4.748e-20 0.32
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 5.097e-20 0.56
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.069e-19 0.38
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.332e-19 0.30
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.082e-18 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.553e-18 0.30
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.864e-18 0.33
EPHB_MYCTO Epoxide hydrolase B 9.056e-18 0.28
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.206e-17 0.39
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.875e-17 0.29
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 5.508e-17 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.11e-16 0.38
GPAT1_MOUSE Gpam Glycerol-3-phosphate acyltransferase 1, mitochondrial 1.11e-16 0.32
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 1.11e-16 0.39
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 2.22e-16 0.34
RARB_HUMAN RARB Retinoic acid receptor beta 5.551e-16 0.34
THAS_HUMAN TBXAS1 Thromboxane-A synthase 5.551e-16 0.35
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 8.882e-16 0.46
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.221e-15 0.52
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 1.998e-15 0.29
DRD4_RAT Drd4 D(4) dopamine receptor 3.109e-15 0.33
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 3.109e-15 0.31
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.662e-15 0.41
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.166e-14 0.29
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.632e-14 0.39
REST_BORBU resT Telomere resolvase ResT 1.799e-14 0.36
MMP13_HUMAN MMP13 Collagenase 3 1.887e-14 0.41
PGH1_MOUSE Ptgs1 Prostaglandin G/H synthase 1 3.209e-14 0.29
CASB_RAT Csn2 Beta-casein 3.852e-14 0.31
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 4.541e-14 0.37
HDAC8_HUMAN HDAC8 Histone deacetylase 8 6.395e-14 0.57
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.42e-13 0.36
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.84e-13 0.31
MMP3_HUMAN MMP3 Stromelysin-1 3.165e-13 0.38
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 3.905e-13 0.43
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 4.4e-13 0.37
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 4.996e-13 0.51
Q9I056_PSEAE cpg2 Carboxypeptidase G2 5.338e-13 0.28
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 8.722e-13 0.38
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 9.238e-13 0.29
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 1.382e-12 0.39
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 2.2e-12 0.35
Q9BEG3_BOVIN 5-lipoxygenase 3.993e-12 0.30
BXE_CLOBO botE Botulinum neurotoxin type E 4.114e-12 0.30
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 4.858e-12 0.29
FFAR1_MOUSE Ffar1 Free fatty acid receptor 1 6.583e-12 0.30
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 9.7e-12 0.29
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 1.117e-11 0.37
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.343e-11 0.56
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 2.292e-11 0.30
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 2.824e-11 0.39
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 2.999e-11 0.36
HDAC2_HUMAN HDAC2 Histone deacetylase 2 3.183e-11 0.39
CRTM_STAAU crtM 4,4'-diapophytoene synthase 4.538e-11 0.33
MGLL_HUMAN MGLL Monoglyceride lipase 5.717e-11 0.33
Q9Z1J7_RAT Slc1a5 Amino acid transporter 7.054e-11 0.32
Q2PCB5_DICLA ca Carbonic anhydrase 7.655e-11 0.29
GGPPS_YEAST BTS1 Geranylgeranyl pyrophosphate synthase 1.327e-10 0.31
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 1.375e-10 0.29
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.472e-10 0.41
GRIA4_HUMAN GRIA4 Glutamate receptor 4 5.81e-10 0.30
DRD5_RAT Drd5 D(1B) dopamine receptor 7.541e-10 0.29
GALR1_RAT Galr1 Galanin receptor type 1 9.181e-10 0.28
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.017e-09 0.38
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.196e-09 0.37
ISPT_STRPN uppS Isoprenyl transferase 1.361e-09 0.31
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.657e-09 0.37
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.03e-09 0.40
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 2.382e-09 0.34
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.614e-09 0.35
ACE_HUMAN ACE Angiotensin-converting enzyme 2.748e-09 0.34
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 3.038e-09 0.36
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.107e-09 0.31
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.2e-09 0.37
Q53I59_TRYCR PDEC Phosphodiesterase 3.241e-09 0.33
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 3.276e-09 0.35
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 3.45e-09 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.98e-09 0.30
HDAC6_HUMAN HDAC6 Histone deacetylase 6 4.022e-09 0.38
TYTR_TRYBB TPR Trypanothione reductase 4.069e-09 0.33
RARA_HUMAN RARA Retinoic acid receptor alpha 4.66e-09 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 5.126e-09 0.33
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 6.311e-09 0.37
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 6.919e-09 0.36
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 7.149e-09 0.30
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 9.724e-09 0.31
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 1.079e-08 0.36
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 1.1e-08 0.33
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.185e-08 0.41
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.239e-08 0.43
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.428e-08 0.43
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.674e-08 0.32
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 2.687e-08 0.34
B2CL2_HUMAN BCL2L2 Bcl-2-like protein 2 2.934e-08 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.209e-08 0.48
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 3.288e-08 0.31
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.352e-08 0.42
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.822e-08 0.41
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.937e-08 0.37
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 5.162e-08 0.40
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 6.187e-08 0.35
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 8.23e-08 0.31
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 8.775e-08 0.30
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 8.833e-08 0.32
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.484e-07 0.30
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.52e-07 0.39
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 1.633e-07 0.36
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 1.647e-07 0.29
NR1H4_HUMAN NR1H4 Bile acid receptor 1.666e-07 0.44
GLUC_HUMAN GCG Glucagon 1.819e-07 0.35
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.917e-07 0.39
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 2.282e-07 0.35
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.432e-07 0.38
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 2.786e-07 0.30
HSF1_MOUSE Hsf1 Heat shock factor protein 1 3.061e-07 0.39
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 3.429e-07 0.31
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 4.233e-07 0.33
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6.662e-07 0.33
AAKG1_HUMAN PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 7.884e-07 0.35
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 1.092e-06 0.28
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.094e-06 0.56
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.104e-06 0.29
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 1.125e-06 0.37
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.144e-06 0.32
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.313e-06 0.34
TA2R_RAT Tbxa2r Thromboxane A2 receptor 1.329e-06 0.30
RARG_HUMAN RARG Retinoic acid receptor gamma 1.44e-06 0.33
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 1.441e-06 0.38
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.459e-06 0.33
Q3Y5H1_9GAMC 3C-like protease 1.591e-06 0.28
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 1.644e-06 0.41
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.845e-06 0.30
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 1.851e-06 0.32
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.959e-06 0.29
Q8MWR1_SPOFR USP Ultraspiracle protein 2.104e-06 0.33
Q8MWR2_SPOFR EcR Ecdysteroid receptor 2.104e-06 0.33
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 2.239e-06 0.37
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 2.259e-06 0.33
Q7ZJM1_9HIV1 pol Integrase 2.834e-06 0.53
GPR55_HUMAN GPR55 G-protein coupled receptor 55 2.942e-06 0.30
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 3.09e-06 0.30
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 3.196e-06 0.37
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 3.352e-06 0.32
GYRA_STAAU gyrA DNA gyrase subunit A 3.399e-06 0.33
PLEC_HUMAN PLEC Plectin 3.406e-06 0.31
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.81e-06 0.41
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 3.831e-06 0.33
THA_HUMAN THRA Thyroid hormone receptor alpha 3.875e-06 0.35
NR1H4_MOUSE Nr1h4 Bile acid receptor 4.01e-06 0.29
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 4.112e-06 0.35
NEP_RABIT MME Neprilysin 4.608e-06 0.32
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.122e-06 0.35
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 5.149e-06 0.37
SGK1_HUMAN SGK1 Serine/threonine-protein kinase Sgk1 6.036e-06 0.32
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 6.806e-06 0.34
UR2R_HUMAN UTS2R Urotensin-2 receptor 7.596e-06 0.33
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 7.852e-06 0.43
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 8.012e-06 0.38
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 8.069e-06 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 9.065e-06 0.45

Dimetacrine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.265e-08 1.00
PRIO_MOUSE Prnp Major prion protein 3.321e-61 0.49
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.136e-38 0.49
DYN2_RAT Dnm2 Dynamin-2 5.245e-27 0.33
DYN2_HUMAN DNM2 Dynamin-2 9.723e-25 0.33
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 5.432e-24 0.49
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 8.179e-18 0.31
CALM_BOVIN CALM Calmodulin 1.039e-17 0.49
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.33e-15 0.51
CALM1_HUMAN CALM1 Calmodulin-1 2.35e-13 0.49
HRH1_CAVPO HRH1 Histamine H1 receptor 1.186e-12 0.49
CDK1_MOUSE Cdk1 Cyclin-dependent kinase 1 1.4e-12 0.31
EIS_MYCTU eis N-acetyltransferase Eis 3.343e-12 0.29
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 7.971e-12 0.51
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 8.99e-12 0.49
EPHA4_MOUSE Epha4 Ephrin type-A receptor 4 1.02e-11 0.38
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 4.854e-11 0.38
TYTR_TRYBB TPR Trypanothione reductase 8.601e-11 0.51
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 1.182e-10 0.31
HRH1_RAT Hrh1 Histamine H1 receptor 2.462e-09 0.59
P2RX4_RAT P2rx4 P2X purinoceptor 4 2.663e-09 0.31
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 5.75e-09 0.49
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.779e-09 0.59
S10A4_HUMAN S100A4 Protein S100-A4 1.129e-08 0.31
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.258e-08 0.34
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 3.452e-08 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.3e-07 0.34
TYTR_TRYCR TPR Trypanothione reductase 1.829e-07 0.51
PRIO_HUMAN PRNP Major prion protein 3.587e-07 0.59
NK1R_RAT Tacr1 Substance-P receptor 4.977e-07 0.36
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.544e-06 0.31
HRH2_HUMAN HRH2 Histamine H2 receptor 4.777e-06 0.59
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 5.915e-06 0.59

Benfluorex

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.593e-07 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.005e-06 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 8.862e-05 1.00
GPR52_HUMAN GPR52 G-protein coupled receptor 52 2.487e-109 0.39
RXFP1_HUMAN RXFP1 Relaxin receptor 1 3.947e-91 0.37
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 1.86e-86 0.39
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.188e-62 0.37
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.062e-56 0.43
CCL2_HUMAN CCL2 C-C motif chemokine 2 1.995e-45 0.34
NK1R_RAT Tacr1 Substance-P receptor 5.424e-45 0.35
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 3.092e-44 0.35
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 5.665e-41 0.35
KPCA_MOUSE Prkca Protein kinase C alpha type 2.568e-40 0.36
NK1R_HUMAN TACR1 Substance-P receptor 3.81e-40 0.39
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 2.904e-39 0.31
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.947e-38 0.30
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.744e-38 0.32
Q99P97_RAT Histone deacetylase 6 1.627e-37 0.30
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 4.262e-36 0.35
AMPB_MOUSE Rnpep Aminopeptidase B 1.377e-35 0.28
AMPL_BOVIN LAP3 Cytosol aminopeptidase 1.377e-35 0.28
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.652e-33 0.36
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 6.844e-32 0.31
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 1.923e-30 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 5.091e-30 0.43
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.032e-29 0.40
NEP_MOUSE Mme Neprilysin 1.242e-29 0.36
NEP_PIG MME Neprilysin 1.758e-29 0.32
CTRC_HUMAN CTRC Chymotrypsin-C 2.318e-27 0.30
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.045e-26 0.37
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 3.002e-26 0.33
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.258e-25 0.33
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 4.579e-25 0.45
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 9.304e-25 0.37
CATD_HUMAN CTSD Cathepsin D 2.658e-24 0.43
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 6.572e-24 0.34
ACOD_HUMAN SCD Acyl-CoA desaturase 8.434e-24 0.36
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.254e-23 0.37
DEF_STAAM def Peptide deformylase 2.815e-23 0.41
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 2.958e-23 0.36
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.194e-23 0.37
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 7.04e-23 0.28
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 1.74e-22 0.33
HDAC1_RAT Hdac1 Histone deacetylase 1 6.791e-22 0.28
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.985e-19 0.34
BACE2_HUMAN BACE2 Beta-secretase 2 2.884e-19 0.43
NADE_BACSU nadE NH(3)-dependent NAD(+) synthetase 3.983e-19 0.30
NEP_RABIT MME Neprilysin 4.492e-19 0.32
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 5.695e-19 0.32
AMP1_PLAFQ M1 family aminopeptidase 6.312e-19 0.36
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 7.449e-19 0.30
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 9.843e-19 0.36
AMPN_PIG ANPEP Aminopeptidase N 1.003e-18 0.37
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.039e-18 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 2.939e-18 0.36
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 3.483e-18 0.33
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 3.565e-18 0.35
RXFP2_HUMAN RXFP2 Relaxin receptor 2 4.879e-18 0.29
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 6.532e-18 0.30
WNK2_HUMAN WNK2 Serine/threonine-protein kinase WNK2 7.773e-18 0.28
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 9.056e-18 0.28
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 9.506e-18 0.37
TRYG1_HUMAN TPSG1 Tryptase gamma 1.006e-17 0.28
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.181e-17 0.34
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 4.248e-17 0.37
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.11e-16 0.41
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.11e-16 0.42
CETP_HUMAN CETP Cholesteryl ester transfer protein 1.11e-16 0.38
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.11e-16 0.38
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.661e-16 0.63
PEPT1_DERPT DERP1 Peptidase 1 7.772e-16 0.34
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 9.992e-16 0.34
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.11e-15 0.33
Q72874_9HIV1 pol Pol polyprotein 1.443e-15 0.35
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.776e-15 0.42
CMA1_HUMAN CMA1 Chymase 2.554e-15 0.44
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 2.776e-15 0.47
TPH2_HUMAN TPH2 Tryptophan 5-hydroxylase 2 2.998e-15 0.29
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 3.109e-15 0.41
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 3.553e-15 0.31
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.219e-15 0.35
TRY1_HUMAN PRSS1 Trypsin-1 6.772e-15 0.39
ELNE_HUMAN ELANE Neutrophil elastase 1.81e-14 0.33
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.409e-14 0.36
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 9.315e-14 0.34
AMPB_RAT Rnpep Aminopeptidase B 1.126e-13 0.31
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.135e-13 0.42
TRY2_BOVIN Anionic trypsin 1.175e-13 0.32
O61059_LEIME LmGT2 Glucose transporter 1.303e-13 0.39
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 2.139e-13 0.32
FA10_BOVIN F10 Coagulation factor X 2.265e-13 0.29
NEP_RAT Mme Neprilysin 2.913e-13 0.32
ACES_ANOGA Ace Acetylcholinesterase 3.759e-13 0.31
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 4.735e-13 0.32
CATL1_BOVIN CTSL Cathepsin L1 5.478e-13 0.32
Q6DMN0_TOXGO CPL Cathepsin L 5.532e-13 0.38
AOFB_RAT Maob Amine oxidase [flavin-containing] B 6.227e-13 0.36
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 7.834e-13 0.31
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 9.17e-13 0.35
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 9.237e-13 0.39
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 9.721e-13 0.37
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.025e-12 0.42
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 1.208e-12 0.35
CATB_HUMAN CTSB Cathepsin B 1.27e-12 0.33
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.514e-12 0.40
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.057e-12 0.40
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 2.059e-12 0.33
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 2.499e-12 0.29
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 2.875e-12 0.40
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 6.104e-12 0.39
O97467_PLAFA ht1 Hexose transporter 1 7.266e-12 0.38
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 8.664e-12 0.30
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 1.082e-11 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 1.42e-11 0.31
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.437e-11 0.28
NEP_HUMAN MME Neprilysin 1.495e-11 0.35
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.562e-11 0.39
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.639e-11 0.33
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 5.46e-11 0.35
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.674e-11 0.37
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 6.595e-11 0.33
FA10_HUMAN F10 Coagulation factor X 7.255e-11 0.38
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 8.682e-11 0.40
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 9.112e-11 0.29
CATL1_HUMAN CTSL Cathepsin L1 1.019e-10 0.38
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.19e-10 0.33
CATB_BOVIN CTSB Cathepsin B 1.436e-10 0.39
PSBA_MARPO psbA Photosystem II protein D1 1.441e-10 0.33
AMPN_MOUSE Anpep Aminopeptidase N 1.577e-10 0.28
ACE_HUMAN ACE Angiotensin-converting enzyme 2.026e-10 0.34
ICMT_HUMAN ICMT Protein-S-isoprenylcysteine O-methyltransferase 2.323e-10 0.34
SORT_HUMAN SORT1 Sortilin 3.828e-10 0.29
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 4.953e-10 0.40
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5.468e-10 0.45
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 5.795e-10 0.34
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 5.866e-10 0.29
THRB_BOVIN F2 Prothrombin 5.921e-10 0.32
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 7.541e-10 0.29
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 8.981e-10 0.29
RHOA_HUMAN RHOA Transforming protein RhoA 9.556e-10 0.30
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 1.333e-09 0.34
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.584e-09 0.38
CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.002e-09 0.40
ITAV_HUMAN ITGAV Integrin alpha-V 2.026e-09 0.36
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.286e-09 0.33
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.63e-09 0.34
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 3.531e-09 0.30
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 4.033e-09 0.37
THER_BACTH npr Thermolysin 4.033e-09 0.30
BACE1_HUMAN BACE1 Beta-secretase 1 4.857e-09 0.43
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 4.956e-09 0.29
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 6.928e-09 0.37
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 9.173e-09 0.39
SHH_MOUSE Shh Sonic hedgehog protein 9.442e-09 0.32
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 1.002e-08 0.36
CETP_RABIT CETP Cholesteryl ester transfer protein 1.274e-08 0.33
CYSP_TRYCR Cruzipain 1.315e-08 0.34
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.381e-08 0.32
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.512e-08 0.32
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.759e-08 0.37
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 1.94e-08 0.32
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.958e-08 0.43
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.499e-08 0.32
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.531e-08 0.63
CATL2_HUMAN CTSV Cathepsin L2 2.576e-08 0.31
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.187e-08 0.48
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.315e-08 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.615e-08 0.30
PAPA1_CARPA Papain 3.743e-08 0.32
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.985e-08 0.29
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 4.556e-08 0.30
AMPL_HUMAN LAP3 Cytosol aminopeptidase 4.687e-08 0.31
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 5.1e-08 0.37
Q95PM0_TRYBR rhodesain Cysteine protease 5.499e-08 0.29
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 6.685e-08 0.30
IDE_HUMAN IDE Insulin-degrading enzyme 7.387e-08 0.40
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 8.249e-08 0.30
ACRO_HUMAN ACR Acrosin 8.269e-08 0.39
CATK_HUMAN CTSK Cathepsin K 8.797e-08 0.34
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 8.867e-08 0.36
HEPS_HUMAN HPN Serine protease hepsin 9.589e-08 0.29
EGLN1_RAT Egln1 Egl nine homolog 1 9.758e-08 0.30
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 1.031e-07 0.29
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 1.313e-07 0.31
ACE_MOUSE Ace Angiotensin-converting enzyme 1.331e-07 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.365e-07 0.28
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.365e-07 0.28
OPRM_RAT Oprm1 Mu-type opioid receptor 1.731e-07 0.35
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.837e-07 0.32
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.041e-07 0.30
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 2.074e-07 0.32
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.105e-07 0.29
PPGB_HUMAN CTSA Lysosomal protective protein 2.317e-07 0.32
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.468e-07 0.35
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 2.679e-07 0.32
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 2.761e-07 0.35
CTRB_BOVIN Chymotrypsinogen B 2.869e-07 0.28
COLA_CLOPE colA Collagenase ColA 3.206e-07 0.35
TPA_HUMAN PLAT Tissue-type plasminogen activator 4.063e-07 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 4.085e-07 0.32
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 4.144e-07 0.30
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.294e-07 0.35
OPRD_MOUSE Oprd1 Delta-type opioid receptor 4.335e-07 0.33
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.396e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.396e-07 0.29
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 4.698e-07 0.39
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 4.754e-07 0.30
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 5.474e-07 0.39
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 6.148e-07 0.28
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 6.161e-07 0.30
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 6.417e-07 0.38
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 6.581e-07 0.33
CXCR5_HUMAN CXCR5 C-X-C chemokine receptor type 5 6.924e-07 0.30
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 8.06e-07 0.30
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 8.204e-07 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 8.204e-07 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 8.204e-07 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 8.204e-07 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 8.204e-07 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 8.204e-07 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 8.204e-07 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 8.204e-07 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 8.204e-07 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 8.204e-07 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 8.204e-07 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 8.204e-07 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 8.204e-07 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 8.204e-07 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 8.204e-07 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 8.204e-07 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 8.204e-07 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 8.204e-07 0.30
CAN1_RAT Capn1 Calpain-1 catalytic subunit 8.308e-07 0.34
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 9.396e-07 0.29
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 9.524e-07 0.38
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.073e-06 0.30
CATS_HUMAN CTSS Cathepsin S 1.163e-06 0.38
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 1.17e-06 0.29
OXDA_MOUSE Dao D-amino-acid oxidase 1.216e-06 0.32
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.24e-06 0.29
PLM1_PLAFA Plasmepsin-1 1.277e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.298e-06 0.34
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 1.482e-06 0.32
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.502e-06 0.36
PERM_HUMAN MPO Myeloperoxidase 1.578e-06 0.34
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.611e-06 0.43
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.7e-06 0.30
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.965e-06 0.30
Q4U254_9ENTO protease Protease 2.179e-06 0.30
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 2.188e-06 0.35
SCAF_HCMVA UL80 Capsid scaffolding protein 2.711e-06 0.35
GLR_HUMAN GCGR Glucagon receptor 2.835e-06 0.31
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 2.934e-06 0.30
Q76129_9HIV1 gag Structural capsid protein 3.305e-06 0.31
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 3.367e-06 0.34
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 3.379e-06 0.34
KLK5_HUMAN KLK5 Kallikrein-5 3.409e-06 0.28
THAS_RAT Tbxas1 Thromboxane-A synthase 3.438e-06 0.34
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 3.477e-06 0.28
FA7_HUMAN F7 Coagulation factor VII 3.593e-06 0.34
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.759e-06 0.35
THRB_HUMAN F2 Prothrombin 3.861e-06 0.37
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 4.586e-06 0.34
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 4.63e-06 0.29
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.666e-06 0.30
CATK_RABIT CTSK Cathepsin K 4.715e-06 0.30
TF_HUMAN F3 Tissue factor 4.749e-06 0.30
KC1G3_HUMAN CSNK1G3 Casein kinase I isoform gamma-3 4.821e-06 0.34
KLK1_HUMAN KLK1 Kallikrein-1 4.904e-06 0.30
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.037e-06 0.28
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 5.236e-06 0.31
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.379e-06 0.28
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 5.393e-06 0.32
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 5.589e-06 0.29
OPRM_CAVPO OPRM1 Mu-type opioid receptor 6.443e-06 0.33
ITB3_HUMAN ITGB3 Integrin beta-3 6.798e-06 0.36
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 7.094e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 7.112e-06 0.29
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 7.34e-06 0.32
LIPE_HUMAN LIPG Endothelial lipase 7.405e-06 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.316e-06 0.42
ACE_RAT Ace Angiotensin-converting enzyme 9.033e-06 0.31
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 9.342e-06 0.33
OPRD_RAT Oprd1 Delta-type opioid receptor 9.608e-06 0.35

Pinaverium

CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00

Acipimox

HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 5.125e-05 1.00
Q44079_AERHY cphA2 Beta-lactamase 7.886e-49 0.31
3HAO_HUMAN HAAO 3-hydroxyanthranilate 3,4-dioxygenase 5.166e-42 0.33
3HAO_RAT Haao 3-hydroxyanthranilate 3,4-dioxygenase 5.166e-42 0.33
HIF1N_HUMAN HIF1AN Hypoxia-inducible factor 1-alpha inhibitor 1.443e-37 0.30
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 3.027e-36 0.38
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 7.502e-31 0.38
BLAB_SERMA Metallo-beta-lactamase type 2 1.248e-24 0.30
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 7.473e-24 0.38
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 3.497e-12 0.30
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 1.275e-11 0.28
DOPO_RAT Dbh Dopamine beta-hydroxylase 3.926e-10 0.34
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.316e-06 0.30
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.798e-06 0.30

Etilefrine

GALR3_HUMAN GALR3 Galanin receptor type 3 0.0001565 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.28e-73 0.43
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.632e-67 0.66
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 1.841e-62 0.43
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 8.029e-62 0.42
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.542e-58 0.39
KYNU_RAT Kynu Kynureninase 4.616e-58 0.46
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 9.543e-52 0.43
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.339e-43 0.40
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 6.694e-38 0.30
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 6.694e-38 0.30
G3HDX1_CRIGR Alpha-1B adrenergic receptor 1.396e-35 0.70
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 6.197e-31 0.39
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.555e-30 0.30
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 7.749e-26 0.32
H9TVJ1_CHISP TyR1 1.444e-23 0.29
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.001e-23 0.45
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 6.654e-21 0.33
KYNU_HUMAN KYNU Kynureninase 8.636e-21 0.46
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 3.488e-18 0.29
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.228e-17 0.39
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.11e-16 0.39
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.11e-16 0.45
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.11e-16 0.36
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 5.551e-16 0.41
Q2PCB5_DICLA ca Carbonic anhydrase 1.753e-13 0.37
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.106e-12 0.41
AOC3_HUMAN AOC3 Membrane primary amine oxidase 5.6e-11 0.43
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 4.535e-10 0.29
PPO1_AGABI PPO1 Polyphenol oxidase 1 7.2e-10 0.31
SPRE_HUMAN SPR Sepiapterin reductase 7.387e-08 0.29
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.786e-07 0.35
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 2.035e-06 0.33
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 4.472e-06 0.28
Q8WSF8_APLCA Soluble acetylcholine receptor 6.677e-06 0.36

Bromhexine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0007929 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.45 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.5886 1.00
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 1.554e-15 0.42
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 7.769e-10 0.42
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 5.339e-08 0.42
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 1.551e-07 0.30

Benzydamine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0008598 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.04371 1.00
CDK1_MOUSE Cdk1 Cyclin-dependent kinase 1 4.087e-61 0.32
ERG7_PNECA ERG7 Lanosterol synthase 1.421e-39 0.33
HPRK_BACSU hprK HPr kinase/phosphorylase 1.775e-36 0.29
UR2R_MACMU UTS2R Urotensin-2 receptor 6.705e-36 0.28
DYN2_RAT Dnm2 Dynamin-2 6.731e-25 0.31
DYN2_HUMAN DNM2 Dynamin-2 8.395e-23 0.31
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.454e-14 0.39
AMYP_RAT Amy2 Pancreatic alpha-amylase 3.922e-13 0.29
HSF1_HUMAN HSF1 Heat shock factor protein 1 5.419e-13 0.33
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.694e-12 0.34
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 7.838e-12 0.29
CALM_BOVIN CALM Calmodulin 2.665e-11 0.30
5HT5A_RAT Htr5a 5-hydroxytryptamine receptor 5A 9.728e-11 0.31
NORA_STAAU norA Quinolone resistance protein NorA 8.18e-10 0.36
KPCG_HUMAN PRKCG Protein kinase C gamma type 2.797e-09 0.36
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 3.227e-09 0.33
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 3.605e-09 0.32
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.624e-09 0.43
KPCB_HUMAN PRKCB Protein kinase C beta type 3.972e-09 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 5.029e-09 0.34
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 1.085e-08 0.32
CALM1_HUMAN CALM1 Calmodulin-1 1.383e-08 0.30
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.469e-08 0.43
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 3.389e-08 0.35
KPCA_HUMAN PRKCA Protein kinase C alpha type 6.701e-08 0.36
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.057e-08 0.40
Q9JKC1_RAT Bche Carboxylic ester hydrolase 8.921e-08 0.28
KCNN2_RAT Kcnn2 Small conductance calcium-activated potassium channel protein 2 9.145e-08 0.30
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 7.408e-07 0.41
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.141e-06 0.36
PERM_HUMAN MPO Myeloperoxidase 1.218e-06 0.33
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 1.275e-06 0.36
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 2.022e-06 0.36
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.772e-06 0.30
LSS_HUMAN LSS Lanosterol synthase 2.795e-06 0.40
CHLE_HUMAN BCHE Cholinesterase 4.566e-06 0.42
KGP1_BOVIN PRKG1 cGMP-dependent protein kinase 1 5.02e-06 0.29
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 5.463e-06 0.28
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 5.712e-06 0.30
ACES_HUMAN ACHE Acetylcholinesterase 5.981e-06 0.65
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 9.729e-06 0.36

Bisacodyl

GPR55_HUMAN GPR55 G-protein coupled receptor 55 0.006571 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.1419 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.2359 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.3929 1.00
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 4.693e-27 0.38
Q44079_AERHY cphA2 Beta-lactamase 2.362e-26 0.33
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 5.472e-12 0.31
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 4.139e-11 0.38
PPO1_AGABI PPO1 Polyphenol oxidase 1 1.441e-10 0.33
TRPV3_HUMAN TRPV3 Transient receptor potential cation channel subfamily V member 3 2.436e-10 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.388e-09 0.33
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.048e-09 0.28
FFAR1_MOUSE Ffar1 Free fatty acid receptor 1 1.107e-07 0.31
CYSP_PLAFA Trophozoite cysteine proteinase 1.288e-07 0.31
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.041e-07 0.29
LUCI_PHOPY Luciferin 4-monooxygenase 4.606e-07 0.35
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 6.864e-07 0.30
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.852e-06 0.33

Glafenine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.07263 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9726 1.00
HRP1_PLAFA Histidine-rich protein PFHRP-II 8.847e-163 0.40
GYRB_MYCS2 gyrB DNA gyrase subunit B 3.881e-75 0.36
HNMT_HUMAN HNMT Histamine N-methyltransferase 3.639e-49 0.39
HNMT_RAT Hnmt Histamine N-methyltransferase 1.342e-48 0.39
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 1.371e-45 0.36
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 3.104e-40 0.34
NTR2_RAT Ntsr2 Neurotensin receptor type 2 5.832e-39 0.31
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 1.225e-34 0.35
ACES_TETCF ache Acetylcholinesterase 1.351e-30 0.34
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.205e-24 0.34
RBP_CHICK Riboflavin-binding protein 1.199e-22 0.36
BXA1_CLOBO botA Botulinum neurotoxin type A 6.328e-21 0.40
MP2K1_MOUSE Map2k1 Dual specificity mitogen-activated protein kinase kinase 1 4.22e-20 0.32
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 2.442e-15 0.35
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.166e-14 0.32
AGP1_YEAST AGP1 General amino acid permease AGP1 6.051e-14 0.39
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 3.645e-13 0.33
MEP2_YEAST MEP2 Ammonium transporter MEP2 1.129e-11 0.34
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 4.13e-11 0.32
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 4.393e-11 0.30
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 8.805e-11 0.29
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 2.086e-10 0.34
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 2.656e-10 0.34
PYGL_RAT Pygl Glycogen phosphorylase, liver form 3.238e-10 0.30
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 3.606e-10 0.32
ACVR1_HUMAN ACVR1 Activin receptor type-1 1.021e-09 0.39
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.503e-09 0.36
AMP1_PLAFQ M1 family aminopeptidase 2.649e-09 0.35
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 1.319e-08 0.42
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 1.323e-08 0.39
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.329e-08 0.38
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.774e-07 0.34
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 2.362e-07 0.37
NTR1_RAT Ntsr1 Neurotensin receptor type 1 2.489e-07 0.28
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 3.131e-07 0.30
A3KMY8_BOVIN GUSB Beta-glucuronidase 4.477e-07 0.30
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.755e-07 0.29
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 4.905e-07 0.29
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 6.148e-07 0.28
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 7.442e-07 0.32
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 1.107e-06 0.34
DPOL_VACCW POL DNA polymerase 1.851e-06 0.32
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5.03e-06 0.30
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 5.174e-06 0.33
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 9.942e-06 0.29

Idebenone

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.9676 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
GSHR_PLAF7 GR3 Glutathione reductase 7.071e-66 0.41
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 7.012e-32 0.39
TYTR_TRYCR TPR Trypanothione reductase 4.497e-30 0.35
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.704e-26 0.46
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 1.429e-18 0.41
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 3.553e-15 0.38
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.382e-11 0.55
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 1.586e-09 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 3.599e-08 0.55
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 5.14e-06 0.29

Ledipasvir

Q5L478_9HEPC NS5A Nonstructural protein 5A 1.694e-171 0.49
POLG_HCVCO Genome polyprotein 1.179e-54 0.44
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 2.137e-08 0.35
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 3.938e-07 0.32

Naloxegol

OPRM_MOUSE Oprm1 Mu-type opioid receptor 9.525e-158 0.66
OPRD_HUMAN OPRD1 Delta-type opioid receptor 8.159e-155 0.81
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.437e-149 0.61
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 8.243e-146 0.64
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.016e-135 0.81
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.144e-122 0.81
OPRM_BOVIN OPRM1 Mu-type opioid receptor 2.967e-108 0.61
OPRD_MOUSE Oprd1 Delta-type opioid receptor 3.026e-105 0.64
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.861e-105 0.61
OPRD_RAT Oprd1 Delta-type opioid receptor 1.597e-103 0.52
OPRM_RAT Oprm1 Mu-type opioid receptor 3.92e-98 0.52
OPRK_RAT Oprk1 Kappa-type opioid receptor 5.047e-55 0.44
TLR4_MOUSE Tlr4 Toll-like receptor 4 4.353e-42 0.44
OPRX_CAVPO OPRL1 Nociceptin receptor 1.241e-41 0.52
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.933e-21 0.36
OPRX_HUMAN OPRL1 Nociceptin receptor 1.11e-16 0.49
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 5.862e-14 0.30
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 5.862e-14 0.30
OPRM_MACMU OPRM1 Mu-type opioid receptor 1.794e-12 0.30
OX1R_HUMAN HCRTR1 Orexin receptor type 1 5.046e-10 0.47

Colfosceril_palmitate

P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 3.385e-152 0.44
TLR2_HUMAN TLR2 Toll-like receptor 2 1.785e-126 0.44
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 6.496e-121 0.39
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 4.316e-86 0.44
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 2.874e-85 0.44
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 4.303e-67 0.44
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 4.388e-59 0.47
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 3.077e-50 0.40
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 1.405e-48 0.63
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 4.281e-45 0.30
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 1.669e-43 0.45
CP2E1_HUMAN CYP2E1 Cytochrome P450 2E1 4.788e-33 0.34
ALF_CANAL FBA1 Fructose-bisphosphate aldolase 1.423e-28 0.37
KPCL_MOUSE Prkch Protein kinase C eta type 2.748e-27 0.53
PPM1A_HUMAN PPM1A Protein phosphatase 1A 2.847e-23 0.29
DXS_ECO27 dxs 1-deoxy-D-xylulose-5-phosphate synthase 4.633e-23 0.28
DXS_MYCTU dxs 1-deoxy-D-xylulose-5-phosphate synthase 4.633e-23 0.28
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.683e-21 0.35
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 2.232e-21 0.44
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 1.226e-20 0.63
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 2.353e-20 0.32
PHLC_BACCE plc Phospholipase C 8.254e-20 0.30
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 3.622e-19 0.31
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 9.841e-19 0.28
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 1.17e-18 0.40
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 7.088e-18 0.28
KPCA_BOVIN PRKCA Protein kinase C alpha type 4.219e-15 0.53
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.11e-14 0.44
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 4.419e-14 0.63
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 2.575e-13 0.52
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 2.441e-11 0.30
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 3.42e-11 0.48
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 3.161e-10 0.36
TLR4_HUMAN TLR4 Toll-like receptor 4 3.392e-10 0.31
Q6UB75_PIG Group VII phospholipase A2 4.979e-10 0.42
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 6.409e-10 0.30
EST1_RABIT Liver carboxylesterase 1 8.397e-10 0.30
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.604e-08 0.78
KPCD_MOUSE Prkcd Protein kinase C delta type 2.223e-08 0.39
LYAM3_HUMAN SELP P-selectin 1.081e-07 0.48
NSMA_RAT Smpd2 Sphingomyelin phosphodiesterase 2 2.617e-07 0.28
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 3.495e-06 0.44
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 8.032e-06 0.33

Ethoheptazine

S12A5_RAT Slc12a5 Solute carrier family 12 member 5 1.67e-136 0.39
CHLE_MOUSE Bche Cholinesterase 5.327e-56 0.31
NK2R_MOUSE Tacr2 Substance-K receptor 1.432e-51 0.32
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.234e-44 0.40
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 5.272e-44 0.35
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.891e-40 0.40
DCMC_MOUSE Mlycd Malonyl-CoA decarboxylase, mitochondrial 1.047e-38 0.35
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 8.828e-37 0.35
PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 1.775e-36 0.29
I6X8D2_MYCTU pks13 Polyketide synthase Pks13 3.875e-36 0.29
S6A13_HUMAN SLC6A13 Sodium- and chloride-dependent GABA transporter 2 3.875e-36 0.29
HCN2_HUMAN HCN2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 7.101e-36 0.28
HCN3_HUMAN HCN3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 7.101e-36 0.28
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.616e-33 0.43
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 1.776e-32 0.29
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.905e-32 0.42
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.876e-31 0.52
OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.387e-29 0.44
OPRX_HUMAN OPRL1 Nociceptin receptor 9.554e-28 0.39
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.819e-27 0.53
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 4.842e-27 0.33
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 6.331e-27 0.58
OPRM_HUMAN OPRM1 Mu-type opioid receptor 8.666e-27 0.89
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.452e-26 0.43
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 7.556e-26 0.30
PPME1_HUMAN PPME1 Protein phosphatase methylesterase 1 4.377e-23 0.28
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.708e-22 0.32
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.066e-22 0.52
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.275e-22 0.89
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 5.31e-22 0.58
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 1.126e-18 0.30
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.081e-18 0.34
TSHB_BOVIN TSHB Thyrotropin subunit beta 2.139e-18 0.29
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 6.785e-18 0.28
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 9.745e-18 0.32
ACES_MOUSE Ache Acetylcholinesterase 1.119e-17 0.31
Q63380_RAT NET Transporter 1.11e-16 0.60
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.11e-16 0.37
OPRM_RAT Oprm1 Mu-type opioid receptor 3.331e-16 0.62
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 6.661e-16 0.62
Q9IP65_HCMV US28 G protein-coupled receptor 2.665e-15 0.29
VACHT_TETCF Vesicular acetylcholine transporter 2.887e-15 0.43
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 4.441e-15 0.29
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 4.441e-15 0.29
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 5.218e-15 0.31
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.599e-14 0.53
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.553e-14 0.68
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 4.685e-14 0.36
PDIA1_HUMAN P4HB Protein disulfide-isomerase 5.007e-14 0.34
TSHR_HUMAN TSHR Thyrotropin receptor 7.261e-14 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.056e-13 0.58
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.818e-13 0.49
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 4.075e-13 0.35
THYX_PBCV1 Probable flavin-dependent thymidylate synthase 4.751e-13 0.28
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.108e-12 0.31
AMPC_CITFR ampC Beta-lactamase 1.562e-12 0.31
BLAC_BACLI penP Beta-lactamase 1.562e-12 0.31
PRIO_SHEEP PRNP Major prion protein 1.835e-12 0.31
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.418e-12 0.53
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 3.63e-12 0.30
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 3.63e-12 0.30
FIBB_HUMAN FGB Fibrinogen beta chain 3.703e-12 0.33
OPRM_CAVPO OPRM1 Mu-type opioid receptor 5.435e-12 0.89
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.662e-12 0.89
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 9.7e-12 0.29
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.828e-12 0.33
SC6A9_MOUSE Slc6a9 Sodium- and chloride-dependent glycine transporter 1 1.067e-11 0.32
CCR5_MACFA CCR5 C-C chemokine receptor type 5 1.141e-11 0.30
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.339e-11 0.28
NK1R_HUMAN TACR1 Substance-P receptor 1.647e-11 0.38
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 4.228e-11 0.29
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 4.543e-11 0.30
US28_HCMVA US28 G-protein coupled receptor homolog US28 7.655e-11 0.29
Q4Q5W4_LEIMA Putative squalene synthase 8.4e-11 0.32
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 9.487e-11 0.33
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.724e-10 0.35
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 5.251e-10 0.32
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.388e-10 0.29
NK1R_CAVPO TACR1 Substance-P receptor 5.396e-10 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 9.601e-10 0.49
NK2R_HUMAN TACR2 Substance-K receptor 9.937e-10 0.34
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.073e-09 0.32
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.089e-09 0.40
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.647e-09 0.29
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.635e-09 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 3.912e-09 0.37
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 7.424e-09 0.31
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 8.255e-09 0.38
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.128e-09 0.29
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 9.249e-09 0.35
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.006e-08 0.33
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.319e-08 0.32
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 1.845e-08 0.33
CHLE_HUMAN BCHE Cholinesterase 2.019e-08 0.31
ACE_HUMAN ACE Angiotensin-converting enzyme 2.242e-08 0.33
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 2.281e-08 0.40
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 2.717e-08 0.33
ACES_HUMAN ACHE Acetylcholinesterase 3.327e-08 0.34
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 5.554e-08 0.43
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 8.893e-08 0.33
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 9.873e-08 0.42
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.008e-07 0.52
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.031e-07 0.29
CHKA_HUMAN CHKA Choline kinase alpha 1.1e-07 0.33
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.291e-07 0.63
NR1D1_HUMAN NR1D1 Nuclear receptor subfamily 1 group D member 1 1.842e-07 0.33
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.059e-07 0.49
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.205e-07 0.29
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 3.223e-07 0.32
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 4.396e-07 0.29
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 4.763e-07 0.32
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 5.13e-07 0.28
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 5.301e-07 0.30
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 5.935e-07 0.36
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 6.219e-07 0.28
DRD2_RAT Drd2 D(2) dopamine receptor 6.281e-07 0.46
PRIO_HUMAN PRNP Major prion protein 6.596e-07 0.30
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 9.056e-07 0.32
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 9.573e-07 0.32
PRIO_MESAU PRNP Major prion protein 1.13e-06 0.31
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 1.215e-06 0.33
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.468e-06 0.31
NORA_STAAU norA Quinolone resistance protein NorA 2.127e-06 0.31
Q25270_LEIDO beta-tubulin Beta-tubulin 2.185e-06 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 3.12e-06 0.33
FOS_HUMAN FOS Proto-oncogene c-Fos 3.566e-06 0.29
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 3.694e-06 0.35
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.853e-06 0.35
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.34e-06 0.33
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.562e-06 0.34
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 4.596e-06 0.29
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 5.352e-06 0.32
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.353e-06 0.35
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.625e-06 0.46
HRH1_HUMAN HRH1 Histamine H1 receptor 5.876e-06 0.35
GPR55_HUMAN GPR55 G-protein coupled receptor 55 7.368e-06 0.35
OXYR_RAT Oxtr Oxytocin receptor 7.8e-06 0.41
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 8.382e-06 0.35
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 9.638e-06 0.46

Benactyzine

AMYP_RAT Amy2 Pancreatic alpha-amylase 9.938e-126 0.78
Q8WMX0_BOVIN Muscarinic receptor M1 4.684e-109 0.78
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 2.682e-44 0.35
CBX2_HUMAN CBX2 Chromobox protein homolog 2 9.681e-38 0.30
CBX6_HUMAN CBX6 Chromobox protein homolog 6 9.681e-38 0.30
CDY1_HUMAN CDY1; CDY1B Testis-specific chromodomain protein Y 1 9.681e-38 0.30
CDYL_HUMAN CDYL Chromodomain Y-like protein 9.681e-38 0.30
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 5.884e-35 0.78
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.296e-28 0.38
ERG2_YEAST ERG2 C-8 sterol isomerase 1.72e-25 0.38
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.969e-25 0.78
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 8.076e-23 0.30
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 6.03e-22 0.35
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.148e-21 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 6.152e-21 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 6.328e-21 0.43
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 6.526e-21 0.33
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.186e-19 0.31
CBX8_HUMAN CBX8 Chromobox protein homolog 8 2.224e-19 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 5.871e-19 0.78
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.407e-19 0.78
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.975e-18 0.42
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 8.822e-18 0.30
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 1.11e-16 0.38
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.331e-16 0.78
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 1.332e-15 0.30
CBX7_HUMAN CBX7 Chromobox protein homolog 7 1.776e-15 0.30
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 3.442e-15 0.33
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 4.441e-15 0.29
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 4.43e-14 0.31
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.193e-13 0.33
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.063e-12 0.49
CATG_HUMAN CTSG Cathepsin G 2.939e-12 0.31
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 3.774e-12 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.262e-12 0.45
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.239e-11 0.38
GALR3_HUMAN GALR3 Galanin receptor type 3 6.931e-10 0.35
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.805e-09 0.50
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 2.643e-09 0.38
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.025e-09 0.31
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.598e-09 0.29
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 3.863e-09 0.39
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 6.636e-09 0.35
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.999e-08 0.68
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 5.219e-08 0.30
CHLE_HUMAN BCHE Cholinesterase 7.718e-08 0.62
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 8.896e-08 0.68
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.17e-07 0.39
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.511e-07 0.29
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 9.396e-07 0.29
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.03e-06 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.175e-06 0.53
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.936e-06 0.31
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 3.826e-06 0.30
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 4.194e-06 0.32
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.112e-06 0.29

Somatostatin

SSR5_RAT Sstr5 Somatostatin receptor type 5 3.517e-125 0.75
V2R_PIG AVPR2 Vasopressin V2 receptor 1.053e-115 0.41
NK2R_RABIT TACR2 Substance-K receptor 5.658e-99 0.42
EDNRA_PIG EDNRA Endothelin-1 receptor 3.173e-86 0.48
MC3R_HUMAN MC3R Melanocortin receptor 3 6.643e-76 0.46
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 9.839e-71 0.45
ADAM8_HUMAN ADAM8 Disintegrin and metalloproteinase domain-containing protein 8 8.919e-70 0.35
MC5R_MOUSE Mc5r Melanocortin receptor 5 7.632e-68 0.43
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 2.259e-62 0.68
O07911_STAAU agrC AgrC 2.896e-61 0.36
NK2R_MESAU TACR2 Substance-K receptor 3.115e-60 0.45
V2R_BOVIN AVPR2 Vasopressin V2 receptor 6.409e-60 0.40
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.054e-56 0.68
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 9.11e-53 0.75
NK2R_HUMAN TACR2 Substance-K receptor 1.542e-51 0.47
MC4R_HUMAN MC4R Melanocortin receptor 4 3.099e-51 0.51
MC4R_MOUSE Mc4r Melanocortin receptor 4 3.954e-51 0.43
UR2R_RAT Uts2r Urotensin-2 receptor 2.133e-50 0.62
CD36_RAT Cd36 Platelet glycoprotein 4 2.544e-49 0.34
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.713e-44 0.42
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.108e-43 0.42
OXYR_HUMAN OXTR Oxytocin receptor 1.82e-43 0.51
CADH2_HUMAN CDH2 Cadherin-2 1.08e-42 0.34
Q5D7U5_CHICK OXTR Oxytocin-like receptor 5.166e-42 0.33
CHIB_SERMA chiB Chitinase B 4.729e-41 0.41
KISSR_HUMAN KISS1R KiSS-1 receptor 3.436e-40 0.31
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 5.411e-40 0.57
OPRD_RAT Oprd1 Delta-type opioid receptor 1.924e-38 0.48
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 2.47e-38 0.43
MC3R_MOUSE Mc3r Melanocortin receptor 3 4.617e-38 0.40
GALR1_RAT Galr1 Galanin receptor type 1 5.322e-38 0.30
GALR2_RAT Galr2 Galanin receptor type 2 5.322e-38 0.30
OPRM_RAT Oprm1 Mu-type opioid receptor 1.552e-37 0.59
MC5R_HUMAN MC5R Melanocortin receptor 5 4.946e-37 0.46
OPRM_CAVPO OPRM1 Mu-type opioid receptor 6.049e-37 0.42
ITB3_HUMAN ITGB3 Integrin beta-3 1.239e-36 0.44
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.424e-36 0.44
ITA5_HUMAN ITGA5 Integrin alpha-5 1.438e-36 0.44
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 7.844e-36 0.39
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 6.044e-35 0.44
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 3.274e-33 0.75
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 7.518e-33 0.61
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 2.777e-31 0.43
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 4.021e-31 0.31
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.841e-29 0.47
V2R_HUMAN AVPR2 Vasopressin V2 receptor 4.138e-28 0.42
NK2R_RAT Tacr2 Substance-K receptor 8.529e-28 0.41
ITAV_HUMAN ITGAV Integrin alpha-V 3.644e-27 0.44
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 8.702e-27 0.30
OXYR_RAT Oxtr Oxytocin receptor 1.424e-26 0.41
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 7.6e-26 0.42
IDE_MOUSE Ide Insulin-degrading enzyme 1.239e-23 0.29
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 1.296e-23 0.38
ITB5_HUMAN ITGB5 Integrin beta-5 1.443e-22 0.37
V1AR_RAT Avpr1a Vasopressin V1a receptor 7.293e-22 0.42
V2R_RAT Avpr2 Vasopressin V2 receptor 1.198e-21 0.41
OXYR_MOUSE Oxtr Oxytocin receptor 6.654e-21 0.33
GRPR_RAT Grpr Gastrin-releasing peptide receptor 1.45e-20 0.29
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 2.601e-20 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.11e-16 0.44
ITB6_HUMAN ITGB6 Integrin beta-6 5.551e-16 0.44
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 1.11e-15 0.31
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.776e-15 0.49
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 3.886e-15 0.31
AGRA_STAAU agrA Accessory gene regulator protein A 5.329e-15 0.37
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 8.46e-14 0.38
CHIB1_ASPFM chiB1 Endochitinase B1 8.771e-14 0.30
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.564e-13 0.38
NK3R_RAT Tacr3 Neuromedin-K receptor 1.573e-13 0.41
ELAS_PSEAE lasB Elastase 2.082e-13 0.31
ENV_HV1H2 env Envelope glycoprotein gp160 3.514e-13 0.29
ITB1_HUMAN ITGB1 Integrin beta-1 4.244e-13 0.44
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 4.345e-13 0.34
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 1.313e-12 0.38
NRP1_RAT Nrp1 Neuropilin-1 5.171e-12 0.29
OPRD_HUMAN OPRD1 Delta-type opioid receptor 6.082e-12 0.39
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.445e-11 0.40
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 8.69e-11 0.30
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.45e-10 0.36
TAT_HV1H2 tat Protein Tat 1.743e-10 0.31
CHIA_SERMA chiA Chitinase A 2.506e-10 0.30
OPRM_HUMAN OPRM1 Mu-type opioid receptor 8.837e-10 0.39
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 2.21e-09 0.42
EDNRA_MOUSE Ednra Endothelin-1 receptor 2.846e-09 0.29
ITA3_HUMAN ITGA3 Integrin alpha-3 4.388e-09 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.048e-09 0.30
OPRK_RAT Oprk1 Kappa-type opioid receptor 6.514e-09 0.35
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 7.526e-09 0.30
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.205e-08 0.30
NK1R_HUMAN TACR1 Substance-P receptor 1.604e-08 0.46
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.035e-08 0.32
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.126e-08 0.30
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 4.151e-08 0.30
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.385e-08 0.36
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 6.035e-08 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 8.729e-08 0.41
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.128e-07 0.37
NMBR_HUMAN NMBR Neuromedin-B receptor 1.352e-07 0.31
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.061e-07 0.30
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.063e-07 0.40
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 3.91e-07 0.33
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.566e-07 0.44
RENI_RAT Ren1 Renin 5.376e-07 0.37
RENI_HUMAN REN Renin 8.235e-07 0.40
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.277e-06 0.29
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.696e-06 0.37
HDAC6_HUMAN HDAC6 Histone deacetylase 6 5.212e-06 0.44
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 6.59e-06 0.30
CHIA_HUMAN CHIA Acidic mammalian chitinase 8.548e-06 0.30

Tixocortol

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 6.58e-119 0.83
Q690N0_BOVIN PGR Progesterone receptor 3.35e-80 0.56
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.208e-71 0.83
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.498e-61 0.41
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.031e-60 0.56
CP19A_HUMAN CYP19A1 Aromatase 3.287e-56 0.46
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.409e-46 0.83
GCR_HUMAN NR3C1 Glucocorticoid receptor 4.499e-44 0.83
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.286e-42 0.56
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.741e-39 0.41
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 5.596e-39 0.31
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 8.156e-34 0.56
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.154e-30 0.57
PRGR_RAT Pgr Progesterone receptor 4.646e-29 0.37
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.241e-27 0.56
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.58e-26 0.44
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.116e-25 0.41
ANDR_RAT Ar Androgen receptor 4.636e-25 0.56
F1Q298_CANLF NR3C1 Glucocorticoid receptor 6.794e-23 0.28
GCR_PIG NR3C1 Glucocorticoid receptor 6.794e-23 0.28
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.17e-22 0.36
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 5.72e-20 0.56
PRGR_RABIT PGR Progesterone receptor 1.019e-18 0.44
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 1.372e-18 0.29
GLNA_HUMAN GLUL Glutamine synthetase 1.485e-17 0.57
GCR_RAT Nr3c1 Glucocorticoid receptor 1.11e-16 0.57
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 8.882e-16 0.41
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.785e-14 0.83
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.929e-14 0.56
IL6_HUMAN IL6 Interleukin-6 6.029e-14 0.57
ANDR_MOUSE Ar Androgen receptor 1.535e-13 0.46
ERG2_YEAST ERG2 C-8 sterol isomerase 1.684e-11 0.46
ANDR_HUMAN AR Androgen receptor 1.218e-10 0.57
PPO2_AGABI PPO2 Polyphenol oxidase 2 6.335e-09 0.68
MCR_RAT Nr3c2 Mineralocorticoid receptor 1.763e-08 0.53
PRGR_HUMAN PGR Progesterone receptor 2.963e-06 0.57
CP19A_RAT Cyp19a1 Aromatase 3.685e-06 0.43
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.283e-06 0.29

Dexetimide

ACES_MOUSE Ache Acetylcholinesterase 3.121e-116 0.42
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 7.913e-103 0.47
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.494e-84 0.44
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 3.29e-83 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 6.843e-75 0.40
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.59e-57 0.43
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 4.563e-51 0.35
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.352e-50 0.35
ACES_HUMAN ACHE Acetylcholinesterase 1.778e-48 0.47
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.654e-46 0.39
VACHT_TETCF Vesicular acetylcholine transporter 1.656e-44 0.34
OPRX_RAT Oprl1 Nociceptin receptor 6.588e-42 0.31
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 9.519e-41 0.32
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 9.519e-41 0.32
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.623e-38 0.41
ACES_RAT Ache Acetylcholinesterase 6.945e-37 0.40
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.157e-33 0.55
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 4.293e-33 0.85
HEPS_HUMAN HPN Serine protease hepsin 7.878e-33 0.35
ACES_ELEEL ache Acetylcholinesterase 3.393e-32 0.38
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.593e-32 0.55
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.772e-31 0.35
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 8.796e-30 0.31
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.386e-29 0.44
DRD1_BOVIN DRD1 D(1A) dopamine receptor 3.346e-29 0.39
OPRX_HUMAN OPRL1 Nociceptin receptor 8.888e-28 0.45
CHLE_HORSE BCHE Cholinesterase 5.906e-26 0.38
GHSR_MOUSE Ghsr Growth hormone secretagogue receptor type 1 2.258e-25 0.31
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 1.217e-24 0.35
EBPL_HUMAN EBPL Emopamil-binding protein-like 6.567e-23 0.37
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 1.056e-22 0.35
BACE1_MOUSE Bace1 Beta-secretase 1 4.19e-22 0.35
CHLE_HUMAN BCHE Cholinesterase 6.658e-21 0.41
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.897e-20 0.45
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 2.413e-20 0.37
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 4.613e-20 0.43
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 8.298e-20 0.29
AMYP_PIG AMY2 Pancreatic alpha-amylase 8.979e-20 0.31
PA_I000X PA Polymerase acidic protein 2.009e-19 0.37
IKZF1_HUMAN IKZF1 DNA-binding protein Ikaros 4.682e-19 0.30
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 3.29e-18 0.37
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.585e-18 0.40
OPRD_HUMAN OPRD1 Delta-type opioid receptor 9.105e-18 0.45
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 1.379e-17 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.555e-17 0.45
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 1.779e-17 0.32
NK1R_MOUSE Tacr1 Substance-P receptor 3.331e-16 0.31
PA_I34A1 PA Polymerase acidic protein 4.441e-16 0.37
CRBN_HUMAN CRBN Protein cereblon 6.661e-16 0.30
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 1.221e-15 0.35
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 6.55e-15 0.35
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 9.77e-15 0.41
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 1.321e-14 0.36
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.388e-14 0.32
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.32e-14 0.36
NK3R_CAVPO TACR3 Neuromedin-K receptor 2.583e-13 0.35
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.195e-12 0.32
HRH3_CAVPO HRH3 Histamine H3 receptor 7.297e-12 0.39
MURB_STAAU murB UDP-N-acetylenolpyruvoylglucosamine reductase 7.838e-12 0.29
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.254e-11 0.36
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.327e-11 0.31
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.519e-11 0.33
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 2.181e-11 0.33
DRD2_RAT Drd2 D(2) dopamine receptor 2.404e-11 0.41
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.512e-11 0.37
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 6.987e-11 0.30
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.262e-10 0.43
LAT_MYCTU lat Probable L-lysine-epsilon aminotransferase 1.66e-10 0.31
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.674e-10 0.39
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.527e-10 0.40
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 5.95e-10 0.42
HRH1_CAVPO HRH1 Histamine H1 receptor 6.79e-10 0.34
Q9WTR4_RAT Slc6a2 Transporter 1.244e-09 0.35
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 1.629e-09 0.38
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.883e-09 0.55
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.236e-09 0.32
PDE1C_HUMAN PDE1C Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 3.752e-09 0.29
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 7.135e-09 0.33
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.17e-08 0.34
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.267e-08 0.39
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 1.435e-08 0.30
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 1.654e-08 0.34
ACES_BOVIN ACHE Acetylcholinesterase 1.659e-08 0.38
RGS8_HUMAN RGS8 Regulator of G-protein signaling 8 1.813e-08 0.28
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 4.938e-08 0.35
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 6.428e-08 0.34
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 6.805e-08 0.35
ACES_TETCF ache Acetylcholinesterase 1.589e-07 0.34
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 1.758e-07 0.29
NK1R_HUMAN TACR1 Substance-P receptor 2.755e-07 0.39
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 4.578e-07 0.44
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 4.766e-07 0.44
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 4.905e-07 0.29
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 8.875e-07 0.33
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 9.506e-07 0.43
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 1.166e-06 0.28
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 1.729e-06 0.31
ACHP_LYMST Acetylcholine-binding protein 2.299e-06 0.37
NK2R_MESAU TACR2 Substance-K receptor 2.316e-06 0.35
GP183_HUMAN GPR183 G-protein coupled receptor 183 2.657e-06 0.30
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 3.12e-06 0.29
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.516e-06 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.719e-06 0.33
HRH3_HUMAN HRH3 Histamine H3 receptor 4.833e-06 0.39
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 5.091e-06 0.28
CASP5_HUMAN CASP5 Caspase-5 5.235e-06 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 8.057e-06 0.31

Flubendazole

RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.39e-114 0.59
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 2.832e-75 0.45
KC1D_RAT Csnk1d Casein kinase I isoform delta 8.146e-65 0.43
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.045e-55 0.59
KC1A_BOVIN CSNK1A1 Casein kinase I isoform alpha 3.726e-54 0.38
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 8.217e-40 0.40
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 3.056e-32 0.82
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 5.657e-29 0.33
Q4DCQ3_TRYCC Superoxide dismutase 6.731e-25 0.31
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 7.589e-25 0.38
GYRA_STAAU gyrA DNA gyrase subunit A 1.104e-23 0.40
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.561e-21 0.60
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.198e-20 0.39
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 3.033e-20 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 8.859e-20 0.53
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.551e-16 0.59
GYRB_STAAU gyrB DNA gyrase subunit B 9.659e-15 0.40
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 2.314e-13 0.32
CBPB_HELZE CPB Carboxypeptidase B 3.164e-13 0.29
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 4.948e-13 0.33
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.012e-12 0.82
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 3.144e-12 0.30
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 1.609e-11 0.34
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 2.222e-11 0.41
KLF5_HUMAN KLF5 Krueppel-like factor 5 3.077e-11 0.42
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 3.121e-11 0.32
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 3.122e-11 0.30
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 4.998e-11 0.39
LUCI_RENRE Coelenterazine h 2-monooxygenase 6.367e-11 0.39
HPSE_HUMAN HPSE Heparanase 3.499e-10 0.33
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.316e-09 0.31
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 3.889e-09 0.39
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 4.107e-09 0.35
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 4.402e-09 0.39
THIO_HUMAN TXN Thioredoxin 2.057e-08 0.30
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.806e-08 0.34
STXA_SHIDY stxA Shiga toxin subunit A 2.929e-08 0.29
POLG_HCVCO Genome polyprotein 2.951e-08 0.33
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 7.947e-08 0.29
SHH_MOUSE Shh Sonic hedgehog protein 8.375e-08 0.34
SPRE_HUMAN SPR Sepiapterin reductase 1.031e-07 0.29
EXSA_PSEAE exsA Exoenzyme S synthesis regulatory protein ExsA 2.362e-07 0.29
EIS_MYCTU eis N-acetyltransferase Eis 3.044e-07 0.32
KPYK_STAAR pyk Pyruvate kinase 3.285e-07 0.34
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 3.409e-07 0.33
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 1.182e-06 0.29
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.32e-06 0.30
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.507e-06 0.30
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.542e-06 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.989e-06 0.33
MAP1_ECOLI map Methionine aminopeptidase 4.058e-06 0.42
LUCI_PHOPY Luciferin 4-monooxygenase 5.488e-06 0.42
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 7.85e-06 0.28
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 7.85e-06 0.28
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 8.03e-06 0.29

Etamivan

SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 5.579e-110 0.43
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 9.519e-72 0.43
TLR1_MOUSE Tlr1 Toll-like receptor 1 3.02e-71 0.35
TLR2_MOUSE Tlr2 Toll-like receptor 2 3.02e-71 0.35
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 7.374e-69 0.43
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 2.725e-52 0.43
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 3.151e-48 0.33
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 2e-47 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.602e-47 0.40
TLR1_HUMAN TLR1 Toll-like receptor 1 3.543e-39 0.31
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.254e-38 0.36
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.312e-38 0.30
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 4.407e-38 0.33
PACR_RAT Adcyap1r1 Pituitary adenylate cyclase-activating polypeptide type I receptor 1.023e-37 0.30
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 1.627e-37 0.30
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 1.627e-37 0.30
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 1.007e-36 0.39
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.079e-34 0.34
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.276e-34 0.44
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 5.827e-34 0.29
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 5.931e-32 0.31
OPRD_RAT Oprd1 Delta-type opioid receptor 3.524e-30 0.43
Q53I59_TRYCR PDEC Phosphodiesterase 1.099e-28 0.33
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.227e-28 0.44
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 8.545e-28 0.30
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 1.143e-27 0.34
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.729e-27 0.47
Q49PX0_9POXV N1L N1L 4.724e-27 0.42
DHPR_HUMAN QDPR Dihydropteridine reductase 1.696e-26 0.35
TAU_HUMAN MAPT Microtubule-associated protein tau 4.725e-26 0.40
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.182e-25 0.41
MTSI_SPISQ sssIM CPG DNA methylase 1.291e-25 0.44
KCNB1_HUMAN KCNB1 Potassium voltage-gated channel subfamily B member 1 2.847e-23 0.29
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.159e-23 0.43
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 4.252e-22 0.33
A4_HUMAN APP Amyloid-beta precursor protein 4.297e-21 0.44
TSPO_HUMAN TSPO Translocator protein 5.769e-21 0.31
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.41e-20 0.37
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.467e-20 0.42
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 4.154e-20 0.33
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.747e-20 0.44
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 8.28e-20 0.47
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.894e-19 0.35
LGUL_HUMAN GLO1 Lactoylglutathione lyase 4.308e-19 0.44
COMT_PIG COMT Catechol O-methyltransferase 5.2e-19 0.33
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 9.88e-19 0.44
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 1.039e-18 0.30
DHPR_RAT Qdpr Dihydropteridine reductase 1.125e-18 0.33
O77240_CHOFU EcR Ecdysone receptor isoform A 1.485e-18 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.231e-18 0.44
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 3.673e-18 0.47
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 4.58e-18 0.38
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 7.943e-18 0.41
OPRM_RAT Oprm1 Mu-type opioid receptor 8.944e-18 0.43
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 9.099e-18 0.68
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.033e-17 0.44
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.11e-16 0.34
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.11e-16 0.42
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.11e-16 0.30
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1.11e-16 0.37
EST1_RABIT Liver carboxylesterase 1 2.22e-16 0.35
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 2.22e-16 0.47
CAN_CANAL NCE103 Carbonic anhydrase 4.441e-16 0.41
DYN1_HUMAN DNM1 Dynamin-1 4.441e-16 0.30
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 6.661e-16 0.44
DCOR_HUMAN ODC1 Ornithine decarboxylase 7.772e-16 0.31
ACES_RAT Ache Acetylcholinesterase 9.992e-16 0.35
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.221e-15 0.36
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.443e-15 0.44
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 2.109e-15 0.29
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 2.109e-15 0.29
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 2.109e-15 0.29
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.109e-15 0.29
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 2.109e-15 0.29
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 2.109e-15 0.29
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 2.109e-15 0.29
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 2.109e-15 0.29
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 2.109e-15 0.29
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 2.109e-15 0.29
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 2.109e-15 0.29
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 2.109e-15 0.29
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 2.109e-15 0.29
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 2.109e-15 0.29
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 2.109e-15 0.29
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 2.109e-15 0.29
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 2.109e-15 0.29
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 2.109e-15 0.29
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 2.109e-15 0.29
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 2.109e-15 0.29
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 2.109e-15 0.29
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 2.109e-15 0.29
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 2.109e-15 0.29
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 2.109e-15 0.29
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 2.109e-15 0.29
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 2.109e-15 0.29
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 2.109e-15 0.29
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 2.109e-15 0.29
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 2.109e-15 0.29
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 2.109e-15 0.29
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 2.109e-15 0.29
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 2.109e-15 0.29
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 2.109e-15 0.29
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 2.109e-15 0.29
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 2.109e-15 0.29
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 2.109e-15 0.29
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 2.109e-15 0.29
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 2.109e-15 0.29
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 2.109e-15 0.29
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 2.109e-15 0.29
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 2.109e-15 0.29
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.109e-15 0.29
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 2.109e-15 0.29
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 2.109e-15 0.29
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 2.109e-15 0.29
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 2.109e-15 0.29
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 2.109e-15 0.29
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 2.109e-15 0.29
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 2.554e-15 0.68
OPRK_RAT Oprk1 Kappa-type opioid receptor 6.217e-15 0.37
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 6.883e-15 0.33
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.299e-14 0.39
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.421e-14 0.32
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 2.187e-14 0.31
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.029e-14 0.41
Q9JKC1_RAT Bche Carboxylic ester hydrolase 6.628e-14 0.34
Q43570_TOBAC NtBBF1.1 Zn finger protein 9.137e-14 0.31
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 9.504e-14 0.30
MOT1_RAT Slc16a1 Monocarboxylate transporter 1 1.049e-13 0.31
SHBG_HUMAN SHBG Sex hormone-binding globulin 5.028e-13 0.38
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 5.327e-13 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 6.537e-13 0.36
TYRO_MOUSE Tyr Tyrosinase 1.4e-12 0.31
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.9e-12 0.35
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.812e-12 0.35
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 3.057e-12 0.38
GLR_HUMAN GCGR Glucagon receptor 3.222e-12 0.41
TTHY_HUMAN TTR Transthyretin 3.604e-12 0.41
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 3.85e-12 0.33
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 4.083e-12 0.41
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 4.114e-12 0.30
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 4.226e-12 0.30
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 4.283e-12 0.33
PRIO_SHEEP PRNP Major prion protein 5.213e-12 0.30
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 5.427e-12 0.29
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 9.7e-12 0.29
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 9.942e-12 0.45
Q2PCB5_DICLA ca Carbonic anhydrase 1.007e-11 0.32
Q9RMI3_STAAU fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] 1.227e-11 0.31
IBP3_HUMAN IGFBP3 Insulin-like growth factor-binding protein 3 1.351e-11 0.33
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 1.383e-11 0.28
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.487e-11 0.44
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 1.535e-11 0.35
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.66e-11 0.29
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.99e-11 0.38
ACES_ELEEL ache Acetylcholinesterase 2.197e-11 0.47
O49150_SOLTU Lipoxygenase 2.291e-11 0.31
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.473e-11 0.37
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 4.031e-11 0.30
O96526_LEIMA CRK3 Cdc2-related kinase 5.117e-11 0.32
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5.478e-11 0.35
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 5.889e-11 0.44
OPRD_MOUSE Oprd1 Delta-type opioid receptor 7.84e-11 0.42
PPO2_AGABI PPO2 Polyphenol oxidase 2 8.199e-11 0.35
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 9.421e-11 0.34
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 1.334e-10 0.28
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.564e-10 0.61
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 2.755e-10 0.32
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 3.016e-10 0.35
NANA_STREE nanA Sialidase A 4.398e-10 0.29
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 4.661e-10 0.29
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 6.957e-10 0.33
GLR_RAT Gcgr Glucagon receptor 1.323e-09 0.38
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.417e-09 0.40
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.453e-09 0.44
EP300_HUMAN EP300 Histone acetyltransferase p300 2.122e-09 0.44
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.397e-09 0.34
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 2.49e-09 0.30
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.546e-09 0.34
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.771e-09 0.30
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 3.954e-09 0.35
Q9XYC7_PLAFA HDAC1 Histone deacetylase 5.861e-09 0.30
FOS_HUMAN FOS Proto-oncogene c-Fos 6.163e-09 0.44
TSPO_RAT Tspo Translocator protein 6.481e-09 0.38
Q8Z9J9_SALTI folA Dihydrofolate reductase 6.587e-09 0.38
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 8.657e-09 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.106e-08 0.37
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.155e-08 0.40
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.322e-08 0.29
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.673e-08 0.40
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.974e-08 0.37
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.299e-08 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.522e-08 0.40
TRY1_BOVIN Cationic trypsin 2.612e-08 0.35
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 2.623e-08 0.31
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 4.141e-08 0.35
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 4.355e-08 0.30
REV1_HUMAN REV1 DNA repair protein REV1 4.633e-08 0.30
ACES_HUMAN ACHE Acetylcholinesterase 6.064e-08 0.40
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 6.44e-08 0.29
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 8.073e-08 0.41
OXYR_HUMAN OXTR Oxytocin receptor 8.709e-08 0.32
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 8.767e-08 0.39
MIP_LEGPN mip Outer membrane protein MIP 9.381e-08 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 9.621e-08 0.36
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.227e-07 0.28
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.33e-07 0.42
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.332e-07 0.33
THA_HUMAN THRA Thyroid hormone receptor alpha 1.356e-07 0.37
ECR_BOMMO EcR Ecdysone receptor 1.423e-07 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.521e-07 0.35
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 1.672e-07 0.31
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.806e-07 0.44
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 2.516e-07 0.28
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.644e-07 0.30
RARG_HUMAN RARG Retinoic acid receptor gamma 2.719e-07 0.33
RARA_HUMAN RARA Retinoic acid receptor alpha 2.803e-07 0.30
CHLE_HORSE BCHE Cholinesterase 3.095e-07 0.37
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.205e-07 0.29
FA12_HUMAN F12 Coagulation factor XII 3.33e-07 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.569e-07 0.32
RARB_HUMAN RARB Retinoic acid receptor beta 3.83e-07 0.33
JUN_HUMAN JUN Transcription factor AP-1 4.219e-07 0.41
DRD1_HUMAN DRD1 D(1A) dopamine receptor 5.038e-07 0.37
CAH13_HUMAN CA13 Carbonic anhydrase 13 5.045e-07 0.44
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 5.272e-07 0.34
AGP1_YEAST AGP1 General amino acid permease AGP1 5.803e-07 0.35
HSF1_MOUSE Hsf1 Heat shock factor protein 1 5.846e-07 0.37
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 5.899e-07 0.43
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 5.964e-07 0.35
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 6.83e-07 0.29
EST2_HUMAN CES2 Cocaine esterase 7.16e-07 0.35
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 9.678e-07 0.35
KLK5_HUMAN KLK5 Kallikrein-5 1.005e-06 0.31
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 1.039e-06 0.35
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.146e-06 0.44
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.502e-06 0.37
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.522e-06 0.29
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.557e-06 0.39
NOX1_HUMAN NOX1 NADPH oxidase 1 1.584e-06 0.30
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.701e-06 0.44
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.836e-06 0.31
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 2.007e-06 0.33
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.079e-06 0.44
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 2.175e-06 0.31
Q25270_LEIDO beta-tubulin Beta-tubulin 2.521e-06 0.29
HDAC8_HUMAN HDAC8 Histone deacetylase 8 3.045e-06 0.34
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 3.097e-06 0.36
RYR2_HUMAN RYR2 Ryanodine receptor 2 3.63e-06 0.30
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 3.727e-06 0.29
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.234e-06 0.39
NOX4_HUMAN NOX4 NADPH oxidase 4 4.466e-06 0.38
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 4.647e-06 0.33
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 5.027e-06 0.34
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 6.15e-06 0.39
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.185e-06 0.44
MEX5_CAEEL mex-5 Zinc finger protein mex-5 6.396e-06 0.35
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 8.173e-06 0.41
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 9.135e-06 0.32

Dimetotiazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 7.453e-109 0.49
PRIO_MOUSE Prnp Major prion protein 1.136e-50 0.40
TYTR_TRYCR TPR Trypanothione reductase 3.065e-35 0.40
LYSC1_RAT Lyz1 Lysozyme C-1 8.092e-26 0.32
CALM_BOVIN CALM Calmodulin 9.238e-26 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.94e-21 0.40
BGLR_RAT Gusb Beta-glucuronidase 5.429e-20 0.32
EBPL_HUMAN EBPL Emopamil-binding protein-like 5.429e-20 0.32
CALM1_HUMAN CALM1 Calmodulin-1 2.395e-19 0.40
CHLE_HUMAN BCHE Cholinesterase 6.128e-14 0.52
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 1.628e-11 0.31
VCAM1_HUMAN VCAM1 Vascular cell adhesion protein 1 4.745e-11 0.35
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 7.109e-11 0.31
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.463e-11 0.67
NOX1_HUMAN NOX1 NADPH oxidase 1 1.536e-10 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.292e-10 0.67
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.206e-09 0.30
PRIO_HUMAN PRNP Major prion protein 1.953e-08 0.67
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.584e-07 0.40
HRH1_HUMAN HRH1 Histamine H1 receptor 2.983e-07 0.67
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 8.528e-07 0.32
HRH2_HUMAN HRH2 Histamine H2 receptor 1.346e-06 0.67
Q7T1G6_DANRE trpn1 Ion channel NompC 1.987e-06 0.38
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.409e-06 0.67
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.453e-06 0.40

Difluocortolone

ATTY_RAT Tat Tyrosine aminotransferase 7.054e-100 0.38
GCR_RAT Nr3c1 Glucocorticoid receptor 1.464e-66 0.53
Q690N0_BOVIN PGR Progesterone receptor 1.251e-49 0.72
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.928e-33 0.72
GCR_MOUSE Nr3c1 Glucocorticoid receptor 9.162e-06 0.31

Eugenol

SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 1.978e-99 0.37
NANA_STREE nanA Sialidase A 1.967e-60 0.66
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 2.218e-49 0.35
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 4.87e-40 0.37
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 9.951e-38 0.41
DYR_LACLA folA Dihydrofolate reductase 4.372e-36 0.38
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 4.889e-32 0.46
Q49PX0_9POXV N1L N1L 1.121e-31 0.46
TAU_HUMAN MAPT Microtubule-associated protein tau 1.598e-30 0.43
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 5.304e-30 0.35
MTSI_SPISQ sssIM CPG DNA methylase 2.136e-27 0.47
DHPR_HUMAN QDPR Dihydropteridine reductase 9.253e-27 0.36
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 2.669e-26 0.32
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 7.375e-23 0.47
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.833e-22 0.57
A4_HUMAN APP Amyloid-beta precursor protein 4.856e-22 0.47
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.902e-21 0.53
Q39829_SOYBN Lipoxygenase 7.563e-20 0.32
DHPR_RAT Qdpr Dihydropteridine reductase 7.637e-20 0.36
LGUL_HUMAN GLO1 Lactoylglutathione lyase 3.477e-19 0.47
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 5.58e-19 0.47
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 6.16e-19 0.54
Q9XSW7_PIG Phosphodiesterase 2.139e-18 0.29
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.996e-17 0.46
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.629e-17 0.57
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 3.525e-17 0.33
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 3.525e-17 0.33
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 3.525e-17 0.33
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 3.525e-17 0.33
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 3.525e-17 0.33
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 3.525e-17 0.33
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 3.525e-17 0.33
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 3.525e-17 0.33
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 3.525e-17 0.33
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 3.525e-17 0.33
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 3.525e-17 0.33
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 3.525e-17 0.33
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 3.525e-17 0.33
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 3.525e-17 0.33
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 3.525e-17 0.33
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 3.525e-17 0.33
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 3.525e-17 0.33
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 3.525e-17 0.33
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 3.525e-17 0.33
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 3.525e-17 0.33
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 3.525e-17 0.33
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 3.525e-17 0.33
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 3.525e-17 0.33
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 3.525e-17 0.33
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 3.525e-17 0.33
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 3.525e-17 0.33
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 3.525e-17 0.33
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 3.525e-17 0.33
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 3.525e-17 0.33
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 3.525e-17 0.33
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 3.525e-17 0.33
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 3.525e-17 0.33
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 3.525e-17 0.33
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 3.525e-17 0.33
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 3.525e-17 0.33
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 3.525e-17 0.33
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 3.525e-17 0.33
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 3.525e-17 0.33
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 3.525e-17 0.33
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 3.525e-17 0.33
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 3.525e-17 0.33
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 3.525e-17 0.33
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 3.525e-17 0.33
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 3.525e-17 0.33
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 3.525e-17 0.33
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 3.525e-17 0.33
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 3.525e-17 0.33
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 3.525e-17 0.33
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 3.331e-16 0.34
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 4.441e-16 0.47
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 9.992e-16 0.57
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.332e-15 0.33
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.998e-15 0.50
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 3.442e-15 0.33
DRTS_PLABA Bifunctional dihydrofolate reductase-thymidylate synthase 3.553e-15 0.29
TTHY_HUMAN TTR Transthyretin 3.775e-15 0.57
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.91e-14 0.43
CAN_CANAL NCE103 Carbonic anhydrase 4.752e-14 0.57
FOS_HUMAN FOS Proto-oncogene c-Fos 7.716e-14 0.57
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 8.604e-14 0.40
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 1.528e-13 0.42
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.872e-13 0.57
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.247e-13 0.32
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 2.368e-13 0.33
Q8Z9J9_SALTI folA Dihydrofolate reductase 3.07e-13 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.408e-13 0.34
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.804e-13 0.40
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 8.925e-13 0.35
Q25270_LEIDO beta-tubulin Beta-tubulin 1.603e-12 0.32
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.771e-12 0.37
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.012e-11 0.47
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.858e-11 0.62
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 3.479e-11 0.33
TLR1_MOUSE Tlr1 Toll-like receptor 1 6.08e-11 0.30
TLR2_MOUSE Tlr2 Toll-like receptor 2 6.08e-11 0.30
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.745e-10 0.62
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 2.613e-10 0.37
LAT_MYCTU lat Probable L-lysine-epsilon aminotransferase 3.022e-10 0.30
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 4.161e-10 0.52
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.398e-10 0.29
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 4.927e-10 0.31
EP300_HUMAN EP300 Histone acetyltransferase p300 6.035e-10 0.47
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 8.149e-10 0.31
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.394e-09 0.31
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 2.184e-09 0.29
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 2.191e-09 0.32
JUN_HUMAN JUN Transcription factor AP-1 2.695e-09 0.57
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.9e-09 0.47
CAH13_MOUSE Ca13 Carbonic anhydrase 13 4.267e-09 0.40
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 6.836e-09 0.41
DRD1_HUMAN DRD1 D(1A) dopamine receptor 8.002e-09 0.42
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 8.496e-09 0.32
Q9XYC7_PLAFA HDAC1 Histone deacetylase 9.415e-09 0.29
CALM1_HUMAN CALM1 Calmodulin-1 9.718e-09 0.31
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.322e-08 0.38
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.254e-08 0.53
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.075e-08 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.204e-08 0.39
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.644e-08 0.47
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 6.018e-08 0.42
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 6.272e-08 0.62
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 6.895e-08 0.34
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 7.21e-08 0.36
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.159e-07 0.41
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 1.374e-07 0.40
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.328e-07 0.31
ACES_ELEEL ache Acetylcholinesterase 4.735e-07 0.44
DYR_NEIGO folA Dihydrofolate reductase 5.55e-07 0.29
NANH_CLOPF nanH Sialidase 5.666e-07 0.33
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 7.871e-07 0.33
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 8.174e-07 0.47
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.052e-06 0.30
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.07e-06 0.47
PERM_HUMAN MPO Myeloperoxidase 1.084e-06 0.36
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1.101e-06 0.32
CAH3_BOVIN CA3 Carbonic anhydrase 3 1.166e-06 0.28
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.178e-06 0.35
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.304e-06 0.38
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.355e-06 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.633e-06 0.41
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.788e-06 0.31
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 2.07e-06 0.28
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.876e-06 0.34
CAH13_HUMAN CA13 Carbonic anhydrase 13 4.87e-06 0.47
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 5.823e-06 0.41
DRD5_HUMAN DRD5 D(1B) dopamine receptor 6.953e-06 0.32
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 7.929e-06 0.41

Podophyllin

VE2_HPV1 E2 Regulatory protein E2 1.779e-95 0.77
EDNRB_HUMAN EDNRB Endothelin receptor type B 3.234e-51 0.37
EDNRB_MOUSE Ednrb Endothelin receptor type B 6.218e-51 0.31
EDNRA_HUMAN EDNRA Endothelin-1 receptor 4.114e-46 0.39
EDNRA_MOUSE Ednra Endothelin-1 receptor 9.345e-32 0.31
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.666e-20 0.77
Q9XSW7_PIG Phosphodiesterase 3.028e-18 0.29
EDNRA_RAT Ednra Endothelin-1 receptor 2.22e-16 0.33
HES1_MOUSE Hes1 Transcription factor HES-1 1.443e-15 0.30
EDNRB_PIG EDNRB Endothelin receptor type B 9.586e-13 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.292e-11 0.48
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.889e-11 0.43
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.462e-07 0.48

Cefaloridine

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 2.616e-93 0.88
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.672e-57 0.88
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.365e-50 0.88
B2ZTR6_ACIBA Beta-lactamase 4.056e-45 0.40
D6NSM8_ACIBA ampC Beta-lactamase 4.056e-45 0.40
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.374e-34 0.88
BLA1_STEMA Metallo-beta-lactamase L1 type 3 6.379e-32 0.34
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 5.245e-27 0.33
A2RP81_CITFR blaPER-2 Beta-lactamase 3.663e-18 0.40
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 4.441e-16 0.30
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.249e-13 0.47
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.575e-11 0.62
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.264e-07 0.32
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.849e-07 0.29
STRP_STRP1 ska Streptokinase A 2.383e-07 0.44
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.718e-07 0.31
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.739e-06 0.32
Q25270_LEIDO beta-tubulin Beta-tubulin 2.473e-06 0.29
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 5.557e-06 0.29

Benzoyl_peroxide

EST1_RABIT Liver carboxylesterase 1 8.537e-91 0.58
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.985e-60 0.54
Q8WSF8_APLCA Soluble acetylcholine receptor 1.27e-58 0.47
EST2_HUMAN CES2 Cocaine esterase 3.79e-57 0.58
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.658e-49 0.36
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.694e-41 0.36
EST1_HUMAN CES1 Liver carboxylesterase 1 9.886e-39 0.58
GLT_PYRHO Glutamate transporter homolog 3.875e-36 0.29
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 1.377e-35 0.28
MANR_PSEPU mdlA Mandelate racemase 3.139e-35 0.29
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.081e-34 0.28
ACHP_LYMST Acetylcholine-binding protein 6.975e-33 0.47
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.109e-31 0.30
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 4.259e-31 0.33
BLAB_BACCE Metallo-beta-lactamase type 2 1.184e-30 0.35
USP_DROME usp Protein ultraspiracle 1.034e-29 0.33
LUCI_AQULA Luciferin 4-monooxygenase 3.509e-28 0.32
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.69e-28 0.33
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.614e-27 0.32
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 3.081e-26 0.32
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.119e-26 0.32
Q44079_AERHY cphA2 Beta-lactamase 4.502e-26 0.32
TLR4_MOUSE Tlr4 Toll-like receptor 4 2.916e-25 0.33
BLAB_SERMA Metallo-beta-lactamase type 2 5.379e-25 0.31
ECR_DROME EcR Ecdysone receptor 2.314e-24 0.33
PA_I34A1 PA Polymerase acidic protein 5.248e-24 0.41
AL1A1_RAT Aldh1a1 Retinal dehydrogenase 1 9.719e-24 0.29
Q43014_PRUAV Beta-glucosidase 1.444e-23 0.29
O87171_SPHPI lsdA Dioxygenase 6.377e-23 0.28
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 9.146e-23 0.38
EPHB_MYCTO Epoxide hydrolase B 1.654e-22 0.36
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.276e-22 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 4.28e-22 0.37
Q2PCB5_DICLA ca Carbonic anhydrase 9.473e-22 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.773e-21 0.36
PA_I000X PA Polymerase acidic protein 3.816e-21 0.41
Q6RY99_RAT Tetraspanin 4.282e-21 0.30
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 4.626e-21 0.31
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 6.096e-21 0.42
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 9.197e-21 0.34
LUCI_PHOPY Luciferin 4-monooxygenase 6.863e-19 0.44
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.913e-18 0.33
ECR_BOMMO EcR Ecdysone receptor 3.973e-18 0.33
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 6.531e-18 0.37
TBA_TRYCR Tubulin alpha chain 8.104e-18 0.28
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 1.882e-17 0.33
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 2.278e-17 0.34
FEN1_HUMAN FEN1 Flap endonuclease 1 2.383e-17 0.37
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 3.262e-17 0.37
ACRO_HUMAN ACR Acrosin 4.361e-17 0.40
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.11e-16 0.34
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.22e-16 0.32
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.221e-15 0.43
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.554e-15 0.38
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 3.553e-15 0.45
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 4.441e-15 0.29
E3UJZ5_SPOLI Ecdysone receptor 7.216e-15 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.55e-15 0.46
Q7ZJM1_9HIV1 pol Integrase 4.574e-14 0.36
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 4.874e-14 0.45
POLG_HRV16 Genome polyprotein 9.504e-14 0.30
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.363e-13 0.31
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.373e-13 0.38
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.716e-13 0.42
IL8_HUMAN CXCL8 Interleukin-8 1.95e-13 0.32
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 3.922e-13 0.29
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 4.234e-13 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 7.846e-13 0.34
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 8.257e-13 0.45
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.339e-12 0.41
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 7.105e-12 0.47
SENP6_HUMAN SENP6 Sentrin-specific protease 6 9.866e-12 0.36
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.688e-11 0.38
CATG_HUMAN CTSG Cathepsin G 1.952e-11 0.38
Q25615_ONCVO Chitinase 2.766e-11 0.35
BLAB_AERHY cphA Metallo-beta-lactamase type 2 2.884e-11 0.36
CAH2_BOVIN CA2 Carbonic anhydrase 2 3.365e-11 0.40
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.584e-11 0.36
POLG_CXB3N Genome polyprotein 4.791e-11 0.31
AGP1_YEAST AGP1 General amino acid permease AGP1 5.076e-11 0.29
AROA_ECOLI aroA 3-phosphoshikimate 1-carboxyvinyltransferase 6.394e-11 0.33
CBPA1_BOVIN CPA1 Carboxypeptidase A1 7.156e-11 0.33
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 9.27e-11 0.34
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 1.182e-10 0.31
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.416e-10 0.37
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 1.479e-10 0.28
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.908e-10 0.50
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 2.322e-10 0.29
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.458e-10 0.30
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.021e-09 0.32
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.159e-09 0.39
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 1.174e-09 0.33
H9B8T9_CAPHI CTSB Cathepsin B 1.312e-09 0.31
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.429e-09 0.50
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 2.261e-09 0.34
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.37e-09 0.33
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.152e-09 0.35
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.217e-09 0.33
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 3.698e-09 0.38
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 4.202e-09 0.47
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 5.792e-09 0.34
ACRO_PIG ACR Acrosin 5.817e-09 0.29
DOPO_HUMAN DBH Dopamine beta-hydroxylase 7.167e-09 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 9.339e-09 0.44
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.241e-08 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.241e-08 0.32
STS_HUMAN STS Steryl-sulfatase 1.265e-08 0.38
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.354e-08 0.34
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 1.482e-08 0.35
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.87e-08 0.37
Q49PX0_9POXV N1L N1L 2.006e-08 0.30
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 2.301e-08 0.31
UREA_CANEN Urease 2.516e-08 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.844e-08 0.33
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 4.134e-08 0.29
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 4.355e-08 0.30
POLG_WNV Genome polyprotein 4.989e-08 0.34
HSF1_MOUSE Hsf1 Heat shock factor protein 1 5.419e-08 0.40
PPAP_HUMAN ACP3 Prostatic acid phosphatase 8.352e-08 0.29
KLF5_HUMAN KLF5 Krueppel-like factor 5 8.428e-08 0.40
CAH7_HUMAN CA7 Carbonic anhydrase 7 8.553e-08 0.50
Q8IL32_PLAF7 Heat shock protein 90, putative 8.864e-08 0.37
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.031e-07 0.29
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 1.141e-07 0.33
ELNE_HUMAN ELANE Neutrophil elastase 1.258e-07 0.41
LEG9_HUMAN LGALS9 Galectin-9 1.267e-07 0.34
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 1.356e-07 0.31
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.66e-07 0.29
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.849e-07 0.29
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.907e-07 0.32
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.177e-07 0.42
CTRA_BOVIN Chymotrypsinogen A 2.212e-07 0.31
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.479e-07 0.37
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.307e-07 0.50
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 3.49e-07 0.32
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.672e-07 0.50
CAH3_BOVIN CA3 Carbonic anhydrase 3 4.707e-07 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 5.027e-07 0.36
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 5.406e-07 0.34
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 6.189e-07 0.36
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 7.024e-07 0.32
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 7.754e-07 0.37
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 7.97e-07 0.31
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 8.212e-07 0.31
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 9.904e-07 0.32
EIS_MYCTU eis N-acetyltransferase Eis 1.071e-06 0.30
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.145e-06 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.189e-06 0.41
PRIO_SHEEP PRNP Major prion protein 1.7e-06 0.30
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.808e-06 0.39
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 1.919e-06 0.35
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.072e-06 0.41
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 2.088e-06 0.29
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 2.241e-06 0.34
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 2.359e-06 0.34
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.491e-06 0.50
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.521e-06 0.29
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.539e-06 0.30
KMO_HUMAN KMO Kynurenine 3-monooxygenase 2.63e-06 0.39
LEG1_HUMAN LGALS1 Galectin-1 2.648e-06 0.34
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 3.18e-06 0.41
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.198e-06 0.41
Q91H74_9FLAV Genome polyprotein 3.596e-06 0.33
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 3.961e-06 0.43
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.966e-06 0.35
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 4.431e-06 0.36
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.572e-06 0.50
EST1_PIG Liver carboxylesterase 5.028e-06 0.58
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 5.066e-06 0.33
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.567e-06 0.28
PA21B_HUMAN PLA2G1B Phospholipase A2 8.044e-06 0.31
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 9.133e-06 0.29
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 9.646e-06 0.38
DNAB_MYCTU dnaB Replicative DNA helicase 9.673e-06 0.36

Ceritinib

ALK_HUMAN ALK ALK tyrosine kinase receptor 4.348e-90 0.67
ETV6_HUMAN ETV6 Transcription factor ETV6 3.871e-83 0.67
INSR_RAT Insr Insulin receptor 1.296e-41 0.33
INSR_HUMAN INSR Insulin receptor 8.362e-29 0.67
ST32C_HUMAN STK32C Serine/threonine-protein kinase 32C 1.042e-20 0.33
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 4.774e-15 0.33
ALK_MOUSE Alk ALK tyrosine kinase receptor 1.946e-13 0.33
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 1.946e-13 0.33
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 2.092e-13 0.67
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 3.224e-12 0.33
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 1.793e-10 0.33
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 1.793e-10 0.33
AVR2A_HUMAN ACVR2A Activin receptor type-2A 8.041e-10 0.33
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 8.041e-10 0.33
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 8.041e-10 0.33
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 8.041e-10 0.33
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 2.871e-09 0.33
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 8.591e-09 0.33
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 8.591e-09 0.33
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 8.591e-09 0.33
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 8.591e-09 0.33
MYO3A_HUMAN MYO3A Myosin-IIIa 8.591e-09 0.33
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 8.591e-09 0.33
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 8.591e-09 0.33
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 1.502e-08 0.67
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 2.234e-08 0.33
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 2.234e-08 0.33
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.234e-08 0.33
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.234e-08 0.33
MYO3B_HUMAN MYO3B Myosin-IIIb 2.234e-08 0.33
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 2.234e-08 0.33
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.246e-08 0.67
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 5.187e-08 0.33
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 5.187e-08 0.33
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 5.187e-08 0.33
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 5.187e-08 0.33
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 7.362e-08 0.67
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 1.097e-07 0.33
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1.097e-07 0.33
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 1.097e-07 0.33
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 1.097e-07 0.33
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 2.148e-07 0.33
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 2.148e-07 0.33
AVR2B_HUMAN ACVR2B Activin receptor type-2B 3.938e-07 0.33
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 3.938e-07 0.33
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.938e-07 0.33
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 3.938e-07 0.33
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 6.83e-07 0.33
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 6.83e-07 0.33
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 6.83e-07 0.33
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 6.83e-07 0.33
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 1.129e-06 0.33
INSRR_HUMAN INSRR Insulin receptor-related protein 1.129e-06 0.33
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 1.129e-06 0.33
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.792e-06 0.33
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 1.792e-06 0.33
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 1.792e-06 0.33
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 2.741e-06 0.33
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 2.741e-06 0.33
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 2.741e-06 0.33
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 4.063e-06 0.33
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 4.063e-06 0.33
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 4.063e-06 0.33
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 4.063e-06 0.33
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 4.063e-06 0.33
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 5.855e-06 0.33
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 5.855e-06 0.33
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 5.855e-06 0.33
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 8.229e-06 0.33
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 8.229e-06 0.33
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 8.229e-06 0.33
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 8.229e-06 0.33

Trimebutine

S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 3.629e-88 0.43
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 3.029e-53 0.34
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 4.538e-46 0.41
NK2R_MOUSE Tacr2 Substance-K receptor 4.19e-43 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.116e-31 0.38
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 1.273e-30 0.35
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.641e-27 0.38
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.341e-26 0.31
Q25270_LEIDO beta-tubulin Beta-tubulin 1.397e-21 0.39
ACES_RAT Ache Acetylcholinesterase 4.288e-21 0.33
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.256e-20 0.41
MIP_LEGPN mip Outer membrane protein MIP 3.212e-20 0.32
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.43e-19 0.32
AUR1_CANAL AUR1 Inositol phosphorylceramide synthase 2.301e-18 0.29
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.776e-15 0.35
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 2.442e-15 0.37
FFAR4_RAT Ffar4 Free fatty acid receptor 4 2.776e-15 0.29
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.774e-15 0.43
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.044e-14 0.35
EDNRB_PIG EDNRB Endothelin receptor type B 2.864e-14 0.35
ACES_TETCF ache Acetylcholinesterase 3.408e-14 0.32
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.464e-13 0.29
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 2.119e-13 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 2.151e-13 0.32
SMO_HUMAN SMO Smoothened homolog 2.476e-13 0.35
ACRO_HUMAN ACR Acrosin 3.566e-13 0.34
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 3.734e-13 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 1.05e-12 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.551e-12 0.34
O77240_CHOFU EcR Ecdysone receptor isoform A 2.687e-12 0.29
EDNRA_RAT Ednra Endothelin-1 receptor 3.425e-12 0.35
AK1A1_PIG AKR1A1 Aldo-keto reductase family 1 member A1 4.628e-12 0.29
CD69_HUMAN CD69 Early activation antigen CD69 9.7e-12 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 1.31e-11 0.35
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.263e-11 0.33
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 4.046e-11 0.33
TLR1_MOUSE Tlr1 Toll-like receptor 1 6.481e-11 0.30
TLR2_MOUSE Tlr2 Toll-like receptor 2 6.481e-11 0.30
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 6.976e-11 0.29
Q49PX0_9POXV N1L N1L 1.135e-10 0.38
ACES_ELEEL ache Acetylcholinesterase 3.764e-10 0.39
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 7.541e-10 0.29
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 9.77e-10 0.30
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.003e-09 0.29
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 1.205e-09 0.31
CHLE_HUMAN BCHE Cholinesterase 1.251e-09 0.33
ACES_HUMAN ACHE Acetylcholinesterase 1.441e-09 0.38
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 2.131e-09 0.31
DYR_PNECA Dihydrofolate reductase 2.218e-09 0.43
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 7.778e-09 0.29
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 1.342e-08 0.34
NK1R_CAVPO TACR1 Substance-P receptor 1.729e-08 0.30
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 1.836e-08 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.133e-08 0.35
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 2.253e-08 0.28
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.543e-08 0.29
EDNRB_HUMAN EDNRB Endothelin receptor type B 2.875e-08 0.34
Q53I59_TRYCR PDEC Phosphodiesterase 3.252e-08 0.29
REV1_HUMAN REV1 DNA repair protein REV1 3.632e-08 0.30
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 4.307e-08 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.162e-08 0.30
DYR_RAT Dhfr Dihydrofolate reductase 7.326e-08 0.43
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 7.599e-08 0.43
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 9.613e-08 0.30
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.021e-07 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.109e-07 0.33
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.324e-07 0.28
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.214e-07 0.34
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.352e-07 0.34
CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.458e-07 0.31
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.869e-07 0.35
O49150_SOLTU Lipoxygenase 9.875e-07 0.33
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 1.023e-06 0.28
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.031e-06 0.29
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.165e-06 0.31
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 1.204e-06 0.31
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 1.431e-06 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.721e-06 0.35
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.841e-06 0.28
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 1.857e-06 0.35
KLK5_HUMAN KLK5 Kallikrein-5 2.123e-06 0.29
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 2.224e-06 0.32
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.369e-06 0.29
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 2.611e-06 0.29
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.686e-06 0.32
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 2.814e-06 0.29
PRIO_SHEEP PRNP Major prion protein 3.477e-06 0.28
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 4.506e-06 0.30
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.379e-06 0.28
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.567e-06 0.28
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 6.082e-06 0.32
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 7.142e-06 0.32
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 7.562e-06 0.35
PLD1_RAT Pld1 Phospholipase D1 8.279e-06 0.28
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 8.404e-06 0.28
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 9.25e-06 0.29
ECR_BOMMO EcR Ecdysone receptor 9.508e-06 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.593e-06 0.32

Quinagolide

SSR1_RAT Sstr1 Somatostatin receptor type 1 4.891e-86 0.36
SSR2_RAT Sstr2 Somatostatin receptor type 2 1.718e-76 0.36
TY3H_HUMAN TH Tyrosine 3-monooxygenase 1.897e-44 0.36
DRD3_RAT Drd3 D(3) dopamine receptor 4.951e-22 0.53
DRD2_RAT Drd2 D(2) dopamine receptor 2.988e-20 0.55
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.578e-18 0.36
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.621e-17 0.53
DRD1_RAT Drd1 D(1A) dopamine receptor 1.11e-16 0.38
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.966e-11 0.55
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 4.292e-10 0.33
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.833e-09 0.49
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 7.689e-09 0.55
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.881e-07 0.36
ADCY5_RAT Adcy5 Adenylate cyclase type 5 2.794e-06 0.30
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 3.556e-06 0.33

Brotizolam

PTAFR_HUMAN PTAFR Platelet-activating factor receptor 7.567e-86 0.78
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.46e-07 0.34

Fluclorolone_acetonide

ATTY_RAT Tat Tyrosine aminotransferase 3.701e-82 0.31
Q690N0_BOVIN PGR Progesterone receptor 5.53e-61 0.72
GCR_RAT Nr3c1 Glucocorticoid receptor 4.782e-47 0.49
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.351e-27 0.72
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.104e-12 0.43
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.598e-09 0.29
GLNA_HUMAN GLUL Glutamine synthetase 3.598e-09 0.29
IL6_HUMAN IL6 Interleukin-6 2.362e-07 0.29

Etidocaine

PAG_BACAN pagA Protective antigen 1.815e-81 0.35
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 7.528e-39 0.31
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 4.077e-33 0.42
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 6.231e-20 0.48
LEF_BACAN lef Lethal factor 7.496e-18 0.35
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.887e-15 0.33
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 7.146e-12 0.38
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.698e-11 0.29
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 6.171e-10 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 4.295e-09 0.32
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 8.292e-09 0.29
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 9.324e-09 0.29
AGP1_YEAST AGP1 General amino acid permease AGP1 3.119e-08 0.42
METC_ECOLI metC Cystathionine beta-lyase MetC 1.106e-07 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 2.362e-07 0.29
ACRO_HUMAN ACR Acrosin 1.099e-06 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.341e-06 0.31
IL8_HUMAN CXCL8 Interleukin-8 8.92e-06 0.36

Amorolfine

B6TK44_MAIZE Cycloeucalenol cycloisomerase 1.083e-77 0.80
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 1.658e-59 0.80
Q2TU57_MAIZE Sterol-8,7-isomerase 2.276e-56 0.80
ERG2_YEAST ERG2 C-8 sterol isomerase 3.619e-14 0.80
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.273e-12 0.80
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.965e-09 0.80

Tasimelteon

MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 3.66e-74 0.57
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 4.003e-64 0.57
5HT5A_RAT Htr5a 5-hydroxytryptamine receptor 5A 3.071e-32 0.34
MTR1B_CHICK Melatonin receptor type 1B 1.123e-30 0.35
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 7.1e-21 0.48
SL9A5_HUMAN SLC9A5 Sodium/hydrogen exchanger 5 1.013e-19 0.44
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.628e-19 0.48
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.787e-14 0.48
SL9A2_HUMAN SLC9A2 Sodium/hydrogen exchanger 2 1.174e-13 0.44
MTR1C_XENLA mtnr1c Melatonin receptor type 1C 3.635e-09 0.31
SL9A1_HUMAN SLC9A1 Sodium/hydrogen exchanger 1 3.342e-07 0.50
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 9.571e-07 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.462e-06 0.29

Efinaconazole

Q96W81_ASPFM cyp51B 14-alpha sterol demethylase 1.522e-73 0.59
CP51A_ASPFU cyp51A 14-alpha sterol demethylase Cyp51A 4.669e-54 0.59
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 4.669e-54 0.59
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 1.599e-52 0.36
CP121_MYCTU cyp121 Mycocyclosin synthase 6.897e-46 0.57
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.242e-17 0.57
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 7.607e-08 0.57

Cobicistat

CPNS1_PIG CAPNS1 Calpain small subunit 1 2.335e-71 0.32
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.167e-67 0.40
NK2R_HUMAN TACR2 Substance-K receptor 1.855e-50 0.62
THER_BACTH npr Thermolysin 1.23e-49 0.34
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.33e-41 0.40
CATL1_RAT Ctsl Cathepsin L1 1.818e-38 0.30
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 7.945e-38 0.31
SPLB_STAAU splB Serine protease SplB 1.156e-37 0.30
CYSP_TRYCR Cruzipain 6.064e-37 0.33
CATB_BOVIN CTSB Cathepsin B 1.211e-36 0.32
CANX_CHICK Calpain-1 catalytic subunit 1.377e-35 0.28
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 1.891e-35 0.35
KLK3_HUMAN KLK3 Prostate-specific antigen 9.396e-32 0.30
CATB_HUMAN CTSB Cathepsin B 2.414e-29 0.39
CASR_HUMAN CASR Extracellular calcium-sensing receptor 9.925e-28 0.34
Q72874_9HIV1 pol Pol polyprotein 3.469e-27 0.62
Q9YQ12_9HIV1 protease Protease 1.442e-26 0.80
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 1.741e-25 0.29
Q9NBD4_PLAFA Cysteine protease falcipain-2 1.313e-23 0.29
Q3HTL5_PLAFA fp2B Falcipain 2B 6.377e-23 0.28
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 1.097e-21 0.29
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 5.365e-21 0.33
Q4U254_9ENTO protease Protease 1.204e-20 0.31
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.978e-19 0.62
CATL1_HUMAN CTSL Cathepsin L1 4.337e-19 0.39
MCA2_TRYBB MCA2 Metacaspase 6.095e-19 0.29
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 1.251e-18 0.37
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 3.089e-18 0.34
NK2R_CAVPO TACR2 Substance-K receptor 6.661e-16 0.32
CATD_BOVIN CTSD Cathepsin D 7.772e-16 0.33
CATH_HUMAN CTSH Pro-cathepsin H 1.11e-15 0.30
CATK_HUMAN CTSK Cathepsin K 1.11e-15 0.39
SCAF_HHV11 UL26 Capsid scaffolding protein 3.22e-15 0.30
RENI_HUMAN REN Renin 4.33e-15 0.35
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.799e-14 0.37
Q95PM0_TRYBR rhodesain Cysteine protease 4.963e-14 0.30
PAPA1_CARPA Papain 1.144e-13 0.31
Q9NBA7_PLAFA Cysteine protease falcipain-3 8.032e-11 0.29
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 8.219e-11 0.30
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 3.13e-10 0.32
CATK_MOUSE Ctsk Cathepsin K 5.63e-10 0.29
Q6DMN0_TOXGO CPL Cathepsin L 5.63e-10 0.29
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 7.195e-10 0.62
CATL1_MOUSE Ctsl Cathepsin L1 2.745e-09 0.29
CATS_RAT Ctss Cathepsin S 2.745e-09 0.29
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 4.316e-09 0.28
CATB_MOUSE Ctsb Cathepsin B 1.027e-08 0.29
CASP9_HUMAN CASP9 Caspase-9 1.028e-08 0.29
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 1.099e-08 0.34
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.103e-08 0.29
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 2.719e-08 0.34
O90781_9PLVG HIV-1 protease HIV-1 protease 5.38e-08 0.31
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 6.399e-08 0.34
RASH_HUMAN HRAS GTPase HRas 8.702e-08 0.28
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.188e-07 0.34
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.188e-07 0.34
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.188e-07 0.34
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.188e-07 0.34
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.188e-07 0.34
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.188e-07 0.34
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.188e-07 0.34
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.188e-07 0.34
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.188e-07 0.34
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.188e-07 0.34
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.188e-07 0.34
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.188e-07 0.34
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.188e-07 0.34
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.188e-07 0.34
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.188e-07 0.34
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.188e-07 0.34
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.188e-07 0.34
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.188e-07 0.34
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 1.238e-07 0.30
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 2.147e-07 0.34
PLMN_RAT Plg Plasminogen 4.027e-07 0.29
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 5.076e-07 0.31
CATS_HUMAN CTSS Cathepsin S 9.369e-07 0.31
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.413e-06 0.29
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 1.745e-06 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.433e-06 0.31
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 2.827e-06 0.70
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 3.781e-06 0.34
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 3.781e-06 0.34
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 3.781e-06 0.34
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 3.781e-06 0.34
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 3.781e-06 0.34
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 3.781e-06 0.34
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 3.781e-06 0.34
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 3.781e-06 0.34
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 3.781e-06 0.34
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 3.781e-06 0.34
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 3.781e-06 0.34
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 3.781e-06 0.34
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 3.781e-06 0.34
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 4.551e-06 0.34
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.758e-06 0.34
RENI_RAT Ren1 Renin 9.191e-06 0.30

Canrenoic_acid

S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.618e-71 0.35
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.508e-66 0.41
Q690N0_BOVIN PGR Progesterone receptor 4.331e-52 0.41
SHBG_HUMAN SHBG Sex hormone-binding globulin 9.197e-41 0.41
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 9.844e-41 0.35
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.153e-40 0.35
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 5.791e-40 0.32
CP19A_HUMAN CYP19A1 Aromatase 2.682e-39 0.58
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 5.885e-28 0.34
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.598e-24 0.35
SHBG_RAT Shbg Sex hormone-binding globulin 2.847e-23 0.29
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.107e-22 0.37
ANDR_RAT Ar Androgen receptor 9.852e-20 0.41
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.814e-19 0.34
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 8.29e-19 0.30
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 3.028e-18 0.29
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 4.879e-18 0.29
PRGR_RAT Pgr Progesterone receptor 9.504e-14 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.733e-13 0.34
PRGR_RABIT PGR Progesterone receptor 4.315e-13 0.34
STS_HUMAN STS Steryl-sulfatase 6.912e-13 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.184e-11 0.36
ANDR_MOUSE Ar Androgen receptor 2.977e-11 0.35
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.188e-10 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.754e-09 0.34
GLNA_HUMAN GLUL Glutamine synthetase 2.15e-09 0.29
ANDR_HUMAN AR Androgen receptor 4.739e-09 0.42
ERG2_YEAST ERG2 C-8 sterol isomerase 6.613e-09 0.34
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.329e-08 0.37
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.079e-08 0.41
IL6_HUMAN IL6 Interleukin-6 1.576e-07 0.29
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.101e-06 0.45

Fentonium

Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 4.383e-71 0.57
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 1.455e-70 0.34
Q8WSF8_APLCA Soluble acetylcholine receptor 2.462e-62 0.49
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 4.588e-38 0.69
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 7.229e-38 0.69
LPH_HUMAN LCT Lactase-phlorizin hydrolase 1.443e-37 0.30
ACHP_LYMST Acetylcholine-binding protein 2.646e-34 0.49
MGLL_RAT Mgll Monoglyceride lipase 2.04e-26 0.30
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 2e-23 0.29
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.533e-22 0.55
HDAC1_RAT Hdac1 Histone deacetylase 1 4.708e-22 0.29
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 7.324e-19 0.69
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.11e-16 0.65
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.551e-16 0.69
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 1.11e-15 0.32
Q8WMX0_BOVIN Muscarinic receptor M1 1.443e-15 0.55
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 2.665e-15 0.69
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.552e-15 0.29
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 7.327e-15 0.69
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 6.606e-14 0.55
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.602e-13 0.65
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 4.628e-12 0.29
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 1.853e-11 0.55
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 9.267e-11 0.65
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.246e-10 0.31
Q4Q5W4_LEIMA Putative squalene synthase 8.811e-10 0.28
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 2.273e-09 0.35
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 2.875e-09 0.57
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.23e-08 0.31
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 6.761e-08 0.65
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.624e-07 0.33
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.335e-07 0.29
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 4.454e-07 0.30
CEGT_HUMAN UGCG Ceramide glucosyltransferase 8.7e-07 0.30
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 2.132e-06 0.30

Flumequine

ACEA_MYCTU icl Isocitrate lyase 1.579e-69 0.39
Q47245_ECOLX gyrA DNA gyrase subunit A 3.167e-64 0.49
C3SLN2_ECOLX gyrB DNA gyrase subunit B 1.304e-55 0.49
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.474e-39 0.31
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 9.736e-19 0.33
DPO3_BACSU polC DNA polymerase III PolC-type 1.11e-16 0.32
PARC_STAAU parC DNA topoisomerase 4 subunit A 1.11e-16 0.42
DPO1_THEAQ polA DNA polymerase I, thermostable 6.661e-15 0.30
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.278e-12 0.46
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.063e-08 0.46
GYRA_MYCTU gyrA DNA gyrase subunit A 4.11e-08 0.42
GYRA_STAAU gyrA DNA gyrase subunit A 2.394e-07 0.41
GYRA_ECOLI gyrA DNA gyrase subunit A 2.401e-06 0.41
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 2.544e-06 0.30
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 2.709e-06 0.32
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 3.335e-06 0.36
PARE_STAAU parE DNA topoisomerase 4 subunit B 3.665e-06 0.41
CNR2_RAT Cnr2 Cannabinoid receptor 2 9.186e-06 0.32

Chlorphenoxamine

AMYP_RAT Amy2 Pancreatic alpha-amylase 1.614e-69 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.011e-58 0.40
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 5.592e-48 0.41
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 8.755e-39 0.31
PRIO_MOUSE Prnp Major prion protein 3.917e-38 0.30
Q8IM71_PLAF7 Choline kinase 1.609e-35 0.28
CP19A_RAT Cyp19a1 Aromatase 1.215e-31 0.35
CALM_BOVIN CALM Calmodulin 5.764e-23 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.851e-22 0.52
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.096e-21 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 4.67e-19 0.35
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.111e-18 0.31
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.643e-18 0.29
ATP6_MYCTU atpB ATP synthase subunit a 4.169e-17 0.31
ATPA_MYCTU atpA ATP synthase subunit alpha 4.169e-17 0.31
ATPB_MYCTU atpD ATP synthase subunit beta 4.169e-17 0.31
ATPE_MYCTU atpC ATP synthase epsilon chain 4.169e-17 0.31
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 4.169e-17 0.31
ATPF_MYCTU atpF ATP synthase subunit b 4.169e-17 0.31
ATPG_MYCTU atpG ATP synthase gamma chain 4.169e-17 0.31
ATPL_MYCTU atpE ATP synthase subunit c 4.169e-17 0.31
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 2.22e-15 0.29
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 1.088e-13 0.34
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.118e-11 0.52
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.038e-10 0.52
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.206e-09 0.30
KITH_HHV1 TK Thymidine kinase 1.043e-08 0.34
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.261e-08 0.39
E3UJZ5_SPOLI Ecdysone receptor 1.299e-08 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.411e-08 0.52
CALM1_HUMAN CALM1 Calmodulin-1 1.528e-08 0.30
ECR_BOMMO EcR Ecdysone receptor 3.22e-08 0.35
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 3.632e-08 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.017e-08 0.52
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.552e-08 0.52
HRH2_HUMAN HRH2 Histamine H2 receptor 5.833e-08 0.52
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 7.852e-08 0.52
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.156e-07 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.247e-07 0.52
DNK_DROME dnk Deoxynucleoside kinase 2.101e-07 0.32
TYTR_TRYBB TPR Trypanothione reductase 2.493e-07 0.32
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 3.205e-07 0.29
CHKA_HUMAN CHKA Choline kinase alpha 3.878e-07 0.28
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 4.333e-07 0.32
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 7.333e-07 0.31
USP_DROME usp Protein ultraspiracle 1.641e-06 0.35
HRH1_RAT Hrh1 Histamine H1 receptor 2.187e-06 0.33
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 2.925e-06 0.32
Q8MWR1_SPOFR USP Ultraspiracle protein 3.454e-06 0.31
Q8MWR2_SPOFR EcR Ecdysteroid receptor 3.454e-06 0.31
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.94e-06 0.32
DPOL_VACCW POL DNA polymerase 4.23e-06 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.399e-06 0.52
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 5.501e-06 0.52
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 8.198e-06 0.30

Finafloxacin

ACEA_MYCTU icl Isocitrate lyase 2.88e-69 0.40
Q47245_ECOLX gyrA DNA gyrase subunit A 1.136e-68 0.55
C3SLN2_ECOLX gyrB DNA gyrase subunit B 1.876e-59 0.55
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.639e-41 0.33
DPO3_BACSU polC DNA polymerase III PolC-type 1.084e-21 0.37
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.725e-20 0.36
PARC_STAAU parC DNA topoisomerase 4 subunit A 2.487e-19 0.55
DPO1_THEAQ polA DNA polymerase I, thermostable 4.911e-17 0.35
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 6.11e-11 0.40
GYRA_MYCTU gyrA DNA gyrase subunit A 1.163e-09 0.51
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.488e-07 0.40
GYRA_STAAU gyrA DNA gyrase subunit A 2.986e-07 0.55
GYRA_ECOLI gyrA DNA gyrase subunit A 7.607e-07 0.45
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.38e-06 0.29
PARE_STAAU parE DNA topoisomerase 4 subunit B 2.184e-06 0.43

Fursultiamine

THIT_LACLM thiT Thiamine transporter ThiT 1.721e-63 0.32
TKT_HUMAN TKT Transketolase 9.705e-52 0.52
STABP_HUMAN STAMBP STAM-binding protein 9.25e-06 0.29

Diosmin

CREB1_HUMAN CREB1 Cyclic AMP-responsive element-binding protein 1 6.453e-63 0.33
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.773e-50 0.35
TOP1_RAT Top1 DNA topoisomerase 1 3.639e-49 0.39
FAS_CHICK FASN Fatty acid synthase 4.918e-49 0.39
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.558e-44 0.61
OPRD_PIG OPRD1 Delta-type opioid receptor 5.239e-40 0.32
GOB1_BRUMA Trehalose-phosphatase 4.474e-39 0.31
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.47e-38 0.59
CD22_HUMAN CD22 B-cell receptor CD22 5.753e-38 0.30
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.057e-36 0.45
O96394_LEIAM Arginase 1.105e-35 0.45
ACES_RAT Ache Acetylcholinesterase 1.529e-34 0.37
IL2_HUMAN IL2 Interleukin-2 9.681e-32 0.63
ARGI1_RAT Arg1 Arginase-1 1.49e-31 0.39
CD22_MOUSE Cd22 B-cell receptor CD22 2.487e-27 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 7.732e-27 0.55
CBS_HUMAN CBS Cystathionine beta-synthase 3.634e-24 0.37
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 4.46e-24 0.65
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 9.368e-24 0.42
SIAT1_RAT St6gal1 Beta-galactoside alpha-2,6-sialyltransferase 1 4.035e-23 0.28
SIAT6_RAT St3gal3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 4.035e-23 0.28
BGLR_RAT Gusb Beta-glucuronidase 1.199e-22 0.36
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 3.538e-22 0.39
MDHC_PIG MDH1 Malate dehydrogenase, cytoplasmic 2.886e-19 0.31
Q6VVP7_PLAFA Malate dehydrogenase 2.886e-19 0.31
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 2.159e-18 0.34
B4EH87_BURCJ Lectin 2.778e-18 0.35
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.024e-17 0.58
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 3.331e-17 0.43
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.11e-16 0.32
PLGF_HUMAN PGF Placenta growth factor 1.11e-16 0.32
Q0PJ46_PLAFA LDH Lactate dehydrogenase 4.441e-16 0.31
ELAV3_HUMAN ELAVL3 ELAV-like protein 3 1.399e-14 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.232e-12 0.42
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 1.559e-12 0.30
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.885e-12 0.33
TYRO_HUMAN TYR Tyrosinase 2.095e-12 0.32
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 3.001e-12 0.36
R1AB_SARS rep Replicase polyprotein 1ab 1.573e-11 0.32
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 2.156e-11 0.36
NOX4_HUMAN NOX4 NADPH oxidase 4 4.727e-11 0.40
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 2.791e-10 0.39
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 5.242e-10 0.29
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 6.489e-10 0.41
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.034e-09 0.55
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 1.06e-09 0.41
ACES_ELEEL ache Acetylcholinesterase 1.923e-09 0.32
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 4.099e-09 0.28
DPO1_THEAQ polA DNA polymerase I, thermostable 8.023e-09 0.34
A0A045ISB3_MYCTX ptbB Phosphotyrosine protein phosphatase 1.229e-08 0.31
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.87e-08 0.38
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 6.884e-08 0.45
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 7.799e-08 0.29
DCOR_HUMAN ODC1 Ornithine decarboxylase 8.352e-08 0.29
IL5_MOUSE Il5 Interleukin-5 1.361e-07 0.41
ALDR_PIG AKR1B1 Aldo-keto reductase family 1 member B1 1.956e-07 0.52
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 3.5e-07 0.31
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7.323e-07 0.61
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.317e-06 0.36
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 2.243e-06 0.41
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.052e-06 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.245e-06 0.45
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 3.644e-06 0.43
CAH4_HUMAN CA4 Carbonic anhydrase 4 4.124e-06 0.45
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 5.585e-06 0.34
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 7.628e-06 0.39
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 7.705e-06 0.28
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 9.43e-06 0.32

Xanthinol

CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 4.33e-62 0.40
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.773e-60 0.50
CHIB1_ASPFM chiB1 Endochitinase B1 1.444e-58 0.35
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 5.551e-16 0.40
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 7.983e-14 0.37
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 1.381e-10 0.36
AA2AR_RAT Adora2a Adenosine receptor A2a 9.124e-10 0.49
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.927e-09 0.36
AA1R_CAVPO ADORA1 Adenosine receptor A1 7.982e-08 0.42
AA1R_RAT Adora1 Adenosine receptor A1 8.78e-08 0.49
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.252e-07 0.36
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 8.659e-07 0.43
SAHH_RAT Ahcy Adenosylhomocysteinase 9.501e-07 0.31
CHIA_MOUSE Chia Acidic mammalian chitinase 2.417e-06 0.33
KGP1_BOVIN PRKG1 cGMP-dependent protein kinase 1 5.99e-06 0.29
AA2BR_RAT Adora2b Adenosine receptor A2b 9.684e-06 0.49

Gemeprost

SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 3.307e-61 0.48
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 2.867e-51 0.48
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.648e-49 0.33
NSMA_RAT Smpd2 Sphingomyelin phosphodiesterase 2 5.66e-41 0.30
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 3.622e-38 0.33
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.541e-35 0.48
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 9.125e-30 0.48
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 2.872e-28 0.48
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.998e-15 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.099e-14 0.44
PI2R_HUMAN PTGIR Prostacyclin receptor 1.854e-14 0.48
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 4.452e-14 0.48
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 2.424e-12 0.45
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.048e-10 0.48
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 9.132e-09 0.45
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 3.64e-06 0.29

Amylocaine

USP_DROME usp Protein ultraspiracle 6.843e-56 0.37
EST1_RABIT Liver carboxylesterase 1 6.394e-53 0.38
ECR_DROME EcR Ecdysone receptor 9.746e-46 0.37
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.303e-38 0.32
ECR_BOMMO EcR Ecdysone receptor 1.233e-35 0.37
AMYP_RAT Amy2 Pancreatic alpha-amylase 9.62e-28 0.33
EST2_HUMAN CES2 Cocaine esterase 4.864e-27 0.43
E3UJZ5_SPOLI Ecdysone receptor 1.356e-26 0.37
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 5.528e-26 0.38
DXS_HAEI8 dxs 1-deoxy-D-xylulose-5-phosphate synthase 2.158e-24 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.209e-24 0.38
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 4.783e-24 0.33
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 5.129e-24 0.39
Q8WSF8_APLCA Soluble acetylcholine receptor 8.008e-22 0.31
EST1_HUMAN CES1 Liver carboxylesterase 1 2.205e-17 0.43
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 3.834e-17 0.33
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 3.929e-17 0.33
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.332e-15 0.32
PA_I000X PA Polymerase acidic protein 1.998e-15 0.29
CATG_HUMAN CTSG Cathepsin G 3.553e-15 0.38
Q8WMX0_BOVIN Muscarinic receptor M1 1.643e-13 0.33
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 1.757e-13 0.33
ACHP_LYMST Acetylcholine-binding protein 3.103e-13 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.309e-11 0.31
Q8MWR1_SPOFR USP Ultraspiracle protein 5.149e-11 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 5.149e-11 0.30
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 2.191e-10 0.33
PHLC_BACCE plc Phospholipase C 6.439e-10 0.29
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1.021e-09 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.866e-09 0.29
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 7.167e-09 0.33
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 4.79e-08 0.28
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 6.82e-08 0.31
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 2.488e-07 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 3.205e-07 0.29
PA_I34A1 PA Polymerase acidic protein 3.89e-07 0.29
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 7.045e-07 0.29
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 1.02e-06 0.36
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.603e-06 0.37
EIS_MYCTU eis N-acetyltransferase Eis 1.683e-06 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.803e-06 0.30
GBRB_MUSDO Rdl Gamma-aminobutyric acid receptor subunit beta 4.586e-06 0.30
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 7.855e-06 0.33
CBPA1_BOVIN CPA1 Carboxypeptidase A1 9.178e-06 0.30

Fominoben

SC6A9_MOUSE Slc6a9 Sodium- and chloride-dependent glycine transporter 1 1.147e-53 0.35
GPC6A_MOUSE Gprc6a G-protein coupled receptor family C group 6 member A 2.866e-42 0.37
BKRB1_MACMU BDKRB1 B1 bradykinin receptor 9.65e-39 0.31
Q9MYJ9_RABIT CCR1 Chemokine receptor 4.536e-38 0.30
CBPC2_HUMAN AGBL2 Cytosolic carboxypeptidase 2 1.215e-35 0.28
Q8MWR1_SPOFR USP Ultraspiracle protein 1.267e-31 0.33
Q8MWR2_SPOFR EcR Ecdysteroid receptor 1.267e-31 0.33
PRIO_SHEEP PRNP Major prion protein 2.733e-30 0.31
USP_DROME usp Protein ultraspiracle 6.822e-30 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.76e-28 0.34
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.082e-27 0.34
BTK_MOUSE Btk Tyrosine-protein kinase BTK 1.454e-27 0.34
ECR_BOMMO EcR Ecdysone receptor 1.115e-26 0.33
Q38C41_TRYB2 Phosphotransferase 5.341e-25 0.31
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.537e-24 0.36
ECR_DROME EcR Ecdysone receptor 1.648e-24 0.33
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 9.411e-24 0.41
FTSZ_MYCTU ftsZ Cell division protein FtsZ 1.069e-23 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.807e-22 0.32
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.278e-21 0.34
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.253e-20 0.34
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.004e-18 0.29
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 5.131e-18 0.33
TRAP_STAAM traP Signal transduction protein TRAP 8.314e-18 0.31
E3UJZ5_SPOLI Ecdysone receptor 8.674e-18 0.29
CASR_HUMAN CASR Extracellular calcium-sensing receptor 4.441e-16 0.32
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 5.551e-16 0.34
LIPL_RAT Lpl Lipoprotein lipase 7.772e-16 0.32
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.442e-15 0.37
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.554e-15 0.35
AOC3_RAT Aoc3 Membrane primary amine oxidase 3.997e-15 0.34
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.663e-15 0.39
MCLN3_HUMAN MCOLN3 Mucolipin-3 6.661e-14 0.40
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.906e-13 0.35
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 2.919e-13 0.32
IL8_HUMAN CXCL8 Interleukin-8 4.249e-13 0.31
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.682e-13 0.35
PEPT1_DERPT DERP1 Peptidase 1 6.425e-13 0.36
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 8.857e-13 0.34
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.858e-12 0.34
SC6A9_RAT Slc6a9 Sodium- and chloride-dependent glycine transporter 1 3.244e-12 0.35
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 1.037e-11 0.35
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.421e-11 0.36
PE2R3_RAT Ptger3 Prostaglandin E2 receptor EP3 subtype 4.289e-11 0.33
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 6.832e-11 0.28
PPCE_PIG PREP Prolyl endopeptidase 1.178e-10 0.33
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.289e-10 0.28
BRPF1_HUMAN BRPF1 Peregrin 1.655e-10 0.38
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.735e-10 0.33
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.311e-10 0.31
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 6.538e-10 0.29
WDR5_HUMAN WDR5 WD repeat-containing protein 5 8.547e-10 0.32
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.595e-09 0.34
FA10_HUMAN F10 Coagulation factor X 2.267e-09 0.41
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 2.45e-09 0.30
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.822e-09 0.31
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 5.514e-09 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 6.363e-09 0.33
UREA_CANEN Urease 1.84e-08 0.34
NR1H4_HUMAN NR1H4 Bile acid receptor 2.733e-08 0.35
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 2.757e-08 0.38
STXA_SHIDY stxA Shiga toxin subunit A 5.192e-08 0.28
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 5.618e-08 0.33
GPR55_HUMAN GPR55 G-protein coupled receptor 55 8.085e-08 0.37
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 9.254e-08 0.32
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 9.258e-08 0.33
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 9.628e-08 0.30
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.068e-07 0.30
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 1.193e-07 0.30
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.742e-07 0.41
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.789e-07 0.47
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.256e-07 0.35
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 3.347e-07 0.30
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 3.371e-07 0.34
RCE1_YEAST RCE1 CAAX prenyl protease 2 3.613e-07 0.34
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.837e-07 0.34
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 4.517e-07 0.34
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5.435e-07 0.38
Q6PRC7_IXORI Legumain-like protease 5.547e-07 0.29
Q9YQ12_9HIV1 protease Protease 5.643e-07 0.30
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.436e-07 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.62e-07 0.37
TTHY_HUMAN TTR Transthyretin 1.147e-06 0.31
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.317e-06 0.32
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.453e-06 0.29
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.471e-06 0.33
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.172e-06 0.40
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.694e-06 0.34
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 3.628e-06 0.31
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 4.279e-06 0.34
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 4.42e-06 0.32
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 4.743e-06 0.28
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.303e-06 0.30
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.664e-06 0.47
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 5.988e-06 0.30
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 8.094e-06 0.32
TXK_HUMAN TXK Tyrosine-protein kinase TXK 8.523e-06 0.32

Tedizolid_phosphate

KTHY_HUMAN DTYMK Thymidylate kinase 6.753e-53 0.31
TYSY_LACCA thyA Thymidylate synthase 2.311e-48 0.33
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 1.77e-45 0.29
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 1.77e-45 0.29
TYSY_MYCTU thyA Thymidylate synthase ThyA 1.639e-41 0.33
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.042e-40 0.30
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.892e-39 0.30
Q8T6J6_PLAFA ompdc Orotidine 5'-monophosphate decarboxylase 4.754e-38 0.30
3BHS2_HUMAN HSD3B2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 9.362e-36 0.28
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.81e-32 0.33
TYSY_BOVIN TYMS Thymidylate synthase 8.943e-25 0.30
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 8.978e-23 0.29
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 4.276e-21 0.30
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 1.845e-20 0.34
KITH_RAT Tk1 Thymidine kinase, cytosolic 9.507e-18 0.28
DPOLB_HUMAN POLB DNA polymerase beta 1.116e-13 0.29
FA10_RABIT F10 Coagulation factor X 1.34e-13 0.32
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 4.143e-13 0.35
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.181e-12 0.79
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.314e-12 0.31
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 1.304e-11 0.28
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 3.271e-10 0.31
TYSY_MOUSE Tyms Thymidylate synthase 3.442e-10 0.33
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 3.728e-10 0.32
KTHY_MYCTU tmk Thymidylate kinase 3.599e-09 0.33
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 8.534e-09 0.32
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 1.199e-07 0.28
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 2.118e-07 0.33
O39930_9HEPC NS5b RNA-directed RNA polymerase 2.737e-07 0.30
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.892e-07 0.29
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 4.081e-07 0.30
TYSY_HUMAN TYMS Thymidylate synthase 1.343e-06 0.33
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 1.528e-06 0.32
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 4.084e-06 0.29
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 7.892e-06 0.30
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.676e-06 0.30

Chlortetracycline

MDFA_ECOLI mdfA Multidrug transporter MdfA 7.113e-52 0.35

Ceftolozane

PBPA_PSEAE mrcA Penicillin-binding protein 1A 2.379e-49 0.35
B2ZTR6_ACIBA Beta-lactamase 7.994e-45 0.38
D6NSM8_ACIBA ampC Beta-lactamase 7.994e-45 0.38
Q7DHH4_STAAU mecA MecA 4.538e-44 0.35
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 5.762e-39 0.38
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 3.066e-28 0.35
Q83TT7_ECOLX ampC AmpC 3.066e-28 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.706e-24 0.38
Q3S5C3_SALNE sugE Efflux transporter 7.533e-22 0.35
Q48435_KLEPN bla LAT-2 Beta-lactamase 7.533e-22 0.35
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.562e-19 0.38
A2RP81_CITFR blaPER-2 Beta-lactamase 7.772e-16 0.35
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.309e-09 0.36
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 9.712e-09 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.69e-08 0.28
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 5.04e-08 0.36

Miltefosine

PLB1_CRYNB PLB1 Phospholipase B 1.405e-48 0.32
SC6A8_RAT Slc6a8 Sodium- and chloride-dependent creatine transporter 1 1.695e-47 0.30
DYN1_HUMAN DNM1 Dynamin-1 1.584e-42 0.43
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 1.225e-37 0.30
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 3.705e-35 0.33
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 4.911e-32 0.32
DXS_ECO27 dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.538e-30 0.38
DXS_MYCTU dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.538e-30 0.38
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 5.113e-29 0.47
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 1.26e-27 0.48
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 1.267e-25 0.31
ALF_CANAL FBA1 Fructose-bisphosphate aldolase 1.296e-23 0.31
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.296e-23 0.38
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 1.769e-22 0.34
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 1.558e-21 0.48
PHLC_BACCE plc Phospholipase C 1.126e-19 0.30
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 5.773e-15 0.31
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 6.883e-15 0.28
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.697e-14 0.29
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 2.482e-13 0.29
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 3.049e-13 0.33
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 6.352e-13 0.30
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.923e-12 0.29
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 2.202e-12 0.33
A1ZA98_DROME Jhe Carboxylic ester hydrolase 2.53e-10 0.33
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 9.556e-10 0.45
EST1_RABIT Liver carboxylesterase 1 1.095e-09 0.29
Q6UB75_PIG Group VII phospholipase A2 1.824e-09 0.40
ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 5.367e-09 0.30
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 5.367e-09 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.101e-09 0.32
MGLL_MOUSE Mgll Monoglyceride lipase 1.014e-08 0.32
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 1.517e-08 0.48
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 4.633e-08 0.30
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 5.72e-07 0.32
EST2_HUMAN CES2 Cocaine esterase 1.286e-06 0.33
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.295e-06 0.34
Q8ST54_TRYCR HK Phosphotransferase 1.995e-06 0.28
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 8.822e-06 0.30

Fluocortolone

Q690N0_BOVIN PGR Progesterone receptor 3.655e-43 0.56
GCR_HUMAN NR3C1 Glucocorticoid receptor 9.747e-23 0.56
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.877e-21 0.34
GCR_RAT Nr3c1 Glucocorticoid receptor 6.028e-21 0.38
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 6.661e-16 0.38
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 8.628e-12 0.38
GLNA_HUMAN GLUL Glutamine synthetase 8.628e-12 0.38
IL6_HUMAN IL6 Interleukin-6 2.055e-09 0.38
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.158e-08 0.34
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.773e-08 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.269e-07 0.34
SHBG_HUMAN SHBG Sex hormone-binding globulin 5.282e-07 0.34
GCR_MOUSE Nr3c1 Glucocorticoid receptor 7.484e-07 0.38
CP19A_HUMAN CYP19A1 Aromatase 1.124e-06 0.32

Florantyrone

SIR2_YEAST SIR2 NAD-dependent histone deacetylase SIR2 4.275e-43 0.34
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 1.921e-39 0.31
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 3.169e-24 0.30
KMO_RAT Kmo Kynurenine 3-monooxygenase 6.041e-20 0.47
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 9.052e-19 0.30
CLH1_HUMAN CLTC Clathrin heavy chain 1 9.771e-18 0.28
TYSY_ECOLI thyA Thymidylate synthase 1.11e-16 0.30
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 5.023e-13 0.31
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.595e-12 0.41
BXE_CLOBO botE Botulinum neurotoxin type E 4.628e-12 0.29
FEN1_HUMAN FEN1 Flap endonuclease 1 2.756e-11 0.34
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 1.116e-09 0.36
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.853e-09 0.31
Q53I59_TRYCR PDEC Phosphodiesterase 1.955e-08 0.30
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.872e-07 0.33
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 3.5e-07 0.31
TYTR_TRYBB TPR Trypanothione reductase 8.644e-07 0.30
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 1.071e-06 0.28
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.178e-06 0.43
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.178e-06 0.31
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.237e-06 0.33
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.749e-06 0.30
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 7.093e-06 0.35

Cyclopentamine

ADH4_HUMAN ADH4 All-trans-retinol dehydrogenase [NAD(+)] ADH4 5.166e-42 0.33
CATH_HUMAN CTSH Pro-cathepsin H 1.852e-26 0.33
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 1.921e-14 0.28
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 1.463e-13 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 7.25e-13 0.35
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.437e-11 0.28
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 1.441e-10 0.33
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.324e-07 0.28
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 1.574e-06 0.33

Floctafenine

NR1H2_MOUSE Nr1h2 Oxysterols receptor LXR-beta 1.144e-40 0.32
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.435e-33 0.36
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.897e-33 0.36
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 5.832e-24 0.43
PTGES_HUMAN PTGES Prostaglandin E synthase 6.152e-21 0.34
RXFP1_HUMAN RXFP1 Relaxin receptor 1 6.46e-21 0.32
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 2.484e-18 0.30
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.11e-16 0.40
CP51_SORBI CYP51 Obtusifoliol 14-alpha demethylase 6.661e-16 0.30
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 3.346e-13 0.32
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.188e-11 0.43
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.224e-11 0.33
MENB_MYCTU menB 1,4-dihydroxy-2-naphthoyl-CoA synthase 3.619e-10 0.30
AURKA_HUMAN AURKA Aurora kinase A 3.783e-10 0.42
PRTN3_HUMAN PRTN3 Myeloblastin 9.178e-10 0.29
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 3.003e-09 0.34
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 3.214e-09 0.40
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1.311e-08 0.36
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 7.285e-08 0.33
METC_ECOLI metC Cystathionine beta-lyase MetC 7.347e-08 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.001e-07 0.34
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 2.313e-07 0.32
ANDR_MOUSE Ar Androgen receptor 3.147e-07 0.28
BAD_HUMAN BAD Bcl2-associated agonist of cell death 3.292e-07 0.29
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 6.063e-07 0.36
ACOD_HUMAN SCD Acyl-CoA desaturase 1.115e-06 0.31
AURKB_HUMAN AURKB Aurora kinase B 1.328e-06 0.40
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 4.074e-06 0.30

Eprazinone

CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.658e-38 0.37
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.992e-38 0.37
ACER2_HUMAN ACER2 Alkaline ceramidase 2 4.749e-37 0.29
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 1.195e-36 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.433e-36 0.34
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.633e-33 0.37
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.176e-33 0.42
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.719e-32 0.39
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.233e-27 0.33
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 9.999e-27 0.42
Q8WSF8_APLCA Soluble acetylcholine receptor 3.707e-26 0.32
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 5.379e-25 0.31
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 1.926e-23 0.29
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.851e-23 0.37
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.798e-23 0.39
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 2.956e-22 0.31
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.252e-20 0.37
ACE_MOUSE Ace Angiotensin-converting enzyme 1.973e-19 0.29
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 4.574e-19 0.42
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 1.332e-18 0.30
PRIO_SHEEP PRNP Major prion protein 3.11e-18 0.33
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 4.879e-18 0.29
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 2.072e-17 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.047e-17 0.39
P2RX3_RAT P2rx3 P2X purinoceptor 3 4.292e-17 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.929e-17 0.38
ACHP_LYMST Acetylcholine-binding protein 1.11e-16 0.32
Q63380_RAT NET Transporter 1.11e-16 0.39
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 3.331e-16 0.32
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 3.442e-15 0.32
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 3.553e-15 0.31
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.108e-15 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.332e-14 0.34
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.41e-14 0.36
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 8.193e-14 0.32
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.509e-13 0.36
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.682e-13 0.34
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6.704e-13 0.29
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 7.697e-13 0.29
EST1_RABIT Liver carboxylesterase 1 1.285e-12 0.30
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 1.4e-12 0.31
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 1.4e-12 0.31
FFAR1_RAT Ffar1 Free fatty acid receptor 1 1.964e-12 0.35
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 4.251e-12 0.30
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.597e-12 0.34
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.697e-11 0.33
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.92e-11 0.31
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.142e-11 0.42
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.61e-11 0.28
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.49e-11 0.33
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 4.935e-11 0.32
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.306e-11 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 8.639e-11 0.32
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.334e-10 0.28
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.364e-10 0.39
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.517e-10 0.31
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.522e-10 0.39
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 2.368e-10 0.30
MC4R_HUMAN MC4R Melanocortin receptor 4 2.69e-10 0.52
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.109e-10 0.35
LUXR_ALIFS luxR Transcriptional activator protein LuxR 3.125e-10 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 3.892e-10 0.37
DRD4_HUMAN DRD4 D(4) dopamine receptor 6.587e-10 0.34
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.666e-10 0.48
EST2_HUMAN CES2 Cocaine esterase 7.078e-10 0.36
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.231e-09 0.30
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.531e-09 0.40
CATG_HUMAN CTSG Cathepsin G 1.655e-09 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.105e-09 0.48
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 4.858e-09 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 8.292e-09 0.29
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 8.775e-09 0.38
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.322e-08 0.29
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.338e-08 0.31
DRD1_PIG DRD1 D(1A) dopamine receptor 1.87e-08 0.31
HRH2_HUMAN HRH2 Histamine H2 receptor 2.113e-08 0.33
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.596e-08 0.33
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.986e-08 0.35
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.012e-08 0.31
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.452e-08 0.29
HRH1_HUMAN HRH1 Histamine H1 receptor 3.636e-08 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.044e-08 0.35
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 5.68e-08 0.30
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 6.643e-08 0.31
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 7.707e-08 0.29
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 9.811e-08 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.283e-07 0.34
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.38e-07 0.30
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.4e-07 0.33
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.464e-07 0.32
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.719e-07 0.30
Q9WTR4_RAT Slc6a2 Transporter 2.52e-07 0.34
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 3.049e-07 0.37
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 4.092e-07 0.29
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 4.7e-07 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.959e-07 0.48
DRD2_RAT Drd2 D(2) dopamine receptor 8.16e-07 0.37
PRIO_MESAU PRNP Major prion protein 8.63e-07 0.31
NR1H4_MOUSE Nr1h4 Bile acid receptor 9.911e-07 0.32
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.081e-06 0.33
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 1.135e-06 0.30
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.2e-06 0.31
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.238e-06 0.34
PEPT1_DERPT DERP1 Peptidase 1 1.242e-06 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.417e-06 0.35
CATL2_HUMAN CTSV Cathepsin L2 1.736e-06 0.29
EST1_HUMAN CES1 Liver carboxylesterase 1 2.172e-06 0.36
HRH3_RAT Hrh3 Histamine H3 receptor 2.603e-06 0.33
OPRM_RAT Oprm1 Mu-type opioid receptor 4.947e-06 0.34
ECR_BOMMO EcR Ecdysone receptor 7.368e-06 0.31
CBPA1_BOVIN CPA1 Carboxypeptidase A1 7.732e-06 0.31
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 8.822e-06 0.30

Sodium_oxybate

ALF_CANAL FBA1 Fructose-bisphosphate aldolase 1.187e-23 0.30
ALF_HELPY fba Fructose-bisphosphate aldolase 4.43e-19 0.30
Q6RY99_RAT Tetraspanin 4.29e-18 0.50
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 7.541e-10 0.29
EST1_RABIT Liver carboxylesterase 1 9.425e-07 0.30

Clobutinol

PPOC_ARATH PPOX1 Protoporphyrinogen oxidase 1, chloroplastic 1.016e-21 0.33
CHKA_HUMAN CHKA Choline kinase alpha 7.661e-15 0.34
UR2R_HUMAN UTS2R Urotensin-2 receptor 2.561e-13 0.32
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 1.196e-11 0.28
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.512e-08 0.32
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 1.683e-06 0.29
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.307e-06 0.29
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 4.586e-06 0.30
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 5.547e-06 0.31

Etifoxine

TYTR_TRYBB TPR Trypanothione reductase 1.495e-19 0.32
ICMT_HUMAN ICMT Protein-S-isoprenylcysteine O-methyltransferase 1.274e-11 0.34

Ditazole

PI2R_HUMAN PTGIR Prostacyclin receptor 1.844e-12 0.35
MTP_BOVIN MTTP Microsomal triglyceride transfer protein large subunit 7.801e-08 0.32
REV_HV1H2 rev Protein Rev 1.721e-07 0.29
PI2R_RAT Ptgir Prostacyclin receptor 8.499e-07 0.33
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 1.052e-06 0.30

Coenzyme_M

BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.172e-11 0.38
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.349e-08 0.46
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 1.521e-06 0.43
CAH_METTE Carbonic anhydrase 5.02e-06 0.29

Fusafungine

SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 9.852e-10 0.28
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 1.266e-07 0.28

Articaine

TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 4.383e-07 0.33
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 9.052e-06 0.34