Results of Job: search_3db91048-b550-40c2-9a21-9401d83bad51

Query Target Key Target Name Description P-Value MaxTC

Karacoline

ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 2.487e-06 1.00

Sitosterol

THRB_HUMAN F2 Prothrombin 0.9968 1.00
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 7.597e-103 0.73
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.865e-83 0.68
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 2.131e-74 0.70
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 5.687e-68 0.36
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.897e-67 0.56
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.972e-66 0.53
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 7.968e-66 0.39
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.668e-61 0.48
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.954e-57 0.72
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 3.773e-56 0.70
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.189e-55 0.73
VDR_RAT Vdr Vitamin D3 receptor 2.627e-51 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.811e-45 0.56
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 9.387e-45 0.48
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 2.371e-42 0.37
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 4.226e-42 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 6.366e-40 0.33
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.586e-40 0.54
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 3.269e-39 0.49
VDR_PIG VDR Vitamin D3 receptor 4.754e-38 0.30
VTDB_HUMAN GC Vitamin D-binding protein 4.754e-38 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 3.987e-37 0.60
VDRA_DANRE vdra Vitamin D3 receptor A 4.291e-37 0.30
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 8.297e-37 0.29
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.283e-36 0.46
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.654e-34 0.54
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.303e-33 0.45
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.964e-30 0.38
VDR_HUMAN VDR Vitamin D3 receptor 2.132e-29 0.41
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.063e-28 0.38
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.532e-26 0.58
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 6.795e-26 0.32
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 9.144e-26 0.79
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.436e-24 0.36
VDR_CHICK VDR Vitamin D3 receptor 2.922e-23 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 4.462e-21 0.43
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.832e-20 0.54
VDR_BOVIN VDR Vitamin D3 receptor 4.921e-20 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 3.237e-19 0.41
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.344e-18 0.36
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.698e-18 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 1.11e-16 0.49
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.22e-16 0.54
ECR_DROME EcR Ecdysone receptor 2.22e-16 0.30
ANDR_HUMAN AR Androgen receptor 5.551e-16 0.49
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.661e-16 0.31
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.663e-15 0.51
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7.438e-15 0.44
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.176e-14 0.70
REST_BORBU resT Telomere resolvase ResT 2.798e-14 0.35
ABCBB_HUMAN ABCB11 Bile salt export pump 3.186e-14 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.619e-14 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 8.215e-13 0.53
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.559e-12 0.53
ESR1_HUMAN ESR1 Estrogen receptor 3.32e-12 0.49
ANDR_RAT Ar Androgen receptor 4.219e-12 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.066e-12 0.53
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.066e-12 0.53
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.462e-11 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.274e-11 0.38
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 5.969e-11 0.53
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 5.969e-11 0.53
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.149e-11 0.53
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.365e-10 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.376e-10 0.53
SHH_MOUSE Shh Sonic hedgehog protein 3.63e-10 0.60
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.601e-10 0.56
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.373e-10 0.53
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.349e-09 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.37e-09 0.30
CP19A_HUMAN CYP19A1 Aromatase 2.019e-09 0.53
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.225e-09 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.152e-09 0.29
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.722e-09 0.66
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.109e-09 0.53
GLI1_HUMAN GLI1 Zinc finger protein GLI1 9.718e-09 0.31
DPOLB_RAT Polb DNA polymerase beta 2.644e-08 0.41
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 8.146e-08 0.74
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.17e-08 0.32
ANDR_MOUSE Ar Androgen receptor 1.124e-07 0.32
Q690N0_BOVIN PGR Progesterone receptor 1.742e-07 0.32
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.895e-07 0.29
SHH_HUMAN SHH Sonic hedgehog protein 5.577e-07 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 5.849e-07 0.35
RORG_HUMAN RORC Nuclear receptor ROR-gamma 7.332e-07 0.79
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.611e-06 0.29
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 7.896e-06 0.48

Demethylcotinine

ACHA3_MOUSE Chrna3 Neuronal acetylcholine receptor subunit alpha-3 7.865e-58 0.46
CRTY_PANAN crtY Lycopene beta-cyclase 7.865e-58 0.46
ACHA6_MOUSE Chrna6 Neuronal acetylcholine receptor subunit alpha-6 4.13e-48 0.42
ACHB3_MOUSE Chrnb3 Neuronal acetylcholine receptor subunit beta-3 1.187e-46 0.42
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 2.996e-45 0.46
ACHA4_MOUSE Chrna4 Neuronal acetylcholine receptor subunit alpha-4 8.441e-33 0.46
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 7.016e-27 0.46
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 1.799e-25 0.35
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 3.971e-25 0.46
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 8.794e-23 0.44
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 4.088e-22 0.53
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 7.388e-22 0.40
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 3.965e-21 0.49
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 5.29e-21 0.46
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 7.334e-21 0.53
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.617e-18 0.46
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 8.516e-18 0.46
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 1.11e-15 0.46
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 1.554e-15 0.46
NOS3_PIG NOS3 Nitric oxide synthase, endothelial 2.22e-15 0.29
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 1.61e-14 0.34
ACHA4_CHICK CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 2.487e-14 0.46
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 2.487e-14 0.46
Q17SB2_PLAFA Plasmepsin 4 2.52e-14 0.30
ACHA6_HUMAN CHRNA6 Neuronal acetylcholine receptor subunit alpha-6 2.576e-14 0.46
ACHB3_HUMAN CHRNB3 Neuronal acetylcholine receptor subunit beta-3 2.576e-14 0.46
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.429e-13 0.38
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 2.541e-13 0.46
A9XFY4_MUSDO nAChRalpha5 Nicotinic acetylcholine receptor alpha 5 subunit 3.954e-13 0.53
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 6.873e-13 0.33
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 7.06e-13 0.46
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 9.717e-12 0.46
H6TY12_PERAM Nicotinic acetylcholine receptor alpha8 subunit 1.035e-11 0.30
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.877e-11 0.53
ACHA2_RAT Chrna2 Neuronal acetylcholine receptor subunit alpha-2 5.062e-11 0.46
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.049e-10 0.33
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 2.033e-09 0.32
CP19A_HUMAN CYP19A1 Aromatase 2.661e-09 0.40
8ODP_HUMAN NUDT1 7,8-dihydro-8-oxoguanine triphosphatase 8.506e-09 0.37
ACH4_DROME nAChRbeta2 Acetylcholine receptor subunit beta-like 2 9.214e-09 0.46
THAS_HUMAN TBXAS1 Thromboxane-A synthase 3.861e-08 0.40
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 9.187e-08 0.46
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 1.158e-07 0.29
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 1.563e-07 0.46
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 2.179e-07 0.46
Q8WSF8_APLCA Soluble acetylcholine receptor 2.651e-07 0.46
ACHP_LYMST Acetylcholine-binding protein 7.313e-07 0.46
PTGIS_HUMAN PTGIS Prostacyclin synthase 8.06e-07 0.30
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 1.453e-06 0.29
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.559e-06 0.53
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 1.691e-06 0.46
PNPH_RAT Pnp Purine nucleoside phosphorylase 3.203e-06 0.29

Aminophenol-2

KAT8_HUMAN KAT8 Histone acetyltransferase KAT8 1.321e-49 0.50
KYNU_HUMAN KYNU Kynureninase 1.236e-39 0.31
DOPO_HUMAN DBH Dopamine beta-hydroxylase 2.854e-26 0.38
Q2PCB5_DICLA ca Carbonic anhydrase 1.259e-24 0.39
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 6.772e-20 0.38
I23O1_MOUSE Ido1 Indoleamine 2,3-dioxygenase 1 6.362e-14 0.42
DNLI1_HUMAN LIG1 DNA ligase 1 7.834e-13 0.31
CAH3_BOVIN CA3 Carbonic anhydrase 3 5.877e-12 0.53
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 9.7e-12 0.29
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 3.824e-10 0.39
AOX_TRYBB AOX Alternative oxidase, mitochondrial 8.149e-10 0.31
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 6.379e-09 0.39
Q49PX0_9POXV N1L N1L 1.083e-08 0.31
REV_HV1H2 rev Protein Rev 1.881e-08 0.33
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 4.931e-08 0.50
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 1.578e-07 0.32
EP300_HUMAN EP300 Histone acetyltransferase p300 1.733e-07 0.50
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 5.877e-07 0.53
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 6.132e-07 0.34
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.483e-06 0.43
CAN_YEAST NCE103 Carbonic anhydrase 1.702e-06 0.43
C0IX24_STYPI CA2 Carbonic anhydrase 3.001e-06 0.43
B2V8E3_SULSY Carbonate dehydratase 5.011e-06 0.43
B5SU02_STYPI CA Alpha carbonic anhydrase 5.011e-06 0.43
Q31FD6_HYDCU Carbonic anhydrase, alpha family 5.011e-06 0.43
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 8.551e-06 0.31
A6YCJ1_9METZ Astrosclerin-3 9.924e-06 0.43

Pyrrolezanthine

H9TVJ1_CHISP TyR1 1.076e-27 0.34
NANA_STREE nanA Sialidase A 1.068e-10 0.31
ELOB_HUMAN ELOB Elongin-B 7.541e-10 0.29
ELOC_HUMAN ELOC Elongin-C 7.541e-10 0.29
POLG_CXB3N Genome polyprotein 6.023e-09 0.31
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.649e-08 0.39
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 5.592e-07 0.35
ACLY_RAT Acly ATP-citrate synthase 2.874e-06 0.34
COMT_HUMAN COMT Catechol O-methyltransferase 7.004e-06 0.33

Deoxyaconitine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.197e-19 0.34
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 9.883e-07 0.41

Oxonitine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.796e-17 0.34

Ignavine

Q8WSF8_APLCA Soluble acetylcholine receptor 1.174e-13 0.32
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.684e-11 0.35
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 3.215e-11 0.33
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.364e-11 0.36
ACHP_LYMST Acetylcholine-binding protein 4.926e-08 0.32
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 5.497e-08 0.33
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.194e-07 0.34

Aconitine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 8.645e-13 0.33

Mesaconitine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.481e-12 0.34

Neojiangyouaconitine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 8.637e-12 0.33
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 8.307e-07 0.43

Benzoylmesaconine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.58e-11 0.33

Benzoylaconine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.863e-10 0.33
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 5.962e-06 0.34

Crassicauline-A

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.071e-10 0.32
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 3.265e-06 0.38

Beiwutine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.742e-08 0.32

Foresaconitine

ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 5.638e-08 0.47

Nonadecan-4-yl-4-methoxybenzoate-8-acetyloxy-11-ethyl-6-16-18-trimethoxy-13-methoxymethyl-11-azahexacyclo-7-7-2-12-5-01-10-03-8-013-17

ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 5.638e-08 0.47

Aconifine

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.032e-08 0.31

Anisoylneoline-14-O

ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 8.814e-08 0.60

Hokbusine-A

MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.089e-06 0.32