Results of Job: search_44d415e2-68db-4ec0-baa1-8c6dad22e913

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 6.874e-126 0.51
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 5.334e-77 0.47
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 2.14e-72 0.38
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.078e-66 0.34
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.358e-61 0.36
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 7.23e-60 0.35
MET_HUMAN MET Hepatocyte growth factor receptor 1.18e-49 0.43
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 6.387e-48 0.30
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.932e-46 0.40
CASB_RAT Csn2 Beta-casein 1.117e-39 0.33
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.355e-37 0.34
D4ADR1_RAT Lpar5 Lysophosphatidic acid receptor 5 6.253e-37 0.29
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.702e-36 0.40
Q8IL11_PLAF7 M17 leucyl aminopeptidase 7.556e-36 0.38
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.149e-32 0.39
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.104e-32 0.43
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.313e-31 0.33
BTK_MOUSE Btk Tyrosine-protein kinase BTK 6.453e-31 0.34
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 7.508e-31 0.43
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 1.809e-30 0.33
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.555e-28 0.31
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 3.384e-28 0.42
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 5.245e-27 0.33
AUKBA_XENLA aurkb-a Aurora kinase B-A 6.397e-27 0.43
HGF_HUMAN HGF Hepatocyte growth factor 6.51e-27 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 6.292e-26 0.43
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 6.421e-26 0.36
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 8.133e-25 0.36
KC1D_RAT Csnk1d Casein kinase I isoform delta 2e-24 0.38
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 2.391e-23 0.35
REV1_HUMAN REV1 DNA repair protein REV1 2.88e-23 0.34
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 7.318e-23 0.28
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 2.12e-22 0.31
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.817e-22 0.43
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 3.256e-22 0.34
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 4.688e-22 0.36
TLR4_HUMAN TLR4 Toll-like receptor 4 2.318e-21 0.34
NMT2_HUMAN NMT2 Glycylpeptide N-tetradecanoyltransferase 2 1.105e-20 0.33
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 6.542e-20 0.37
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 2.073e-19 0.31
PRIO_HUMAN PRNP Major prion protein 3.227e-19 0.37
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 1.624e-18 0.33
O70424_RAT Neuropeptide Y-Y2 receptor 2.139e-18 0.29
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.596e-18 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.785e-18 0.32
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 6.009e-18 0.28
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.041e-18 0.39
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 7.668e-18 0.34
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 8.972e-18 0.34
NK2R_MOUSE Tacr2 Substance-K receptor 1.414e-17 0.32
O31272_9GAMM imiS Beta-lactamase 1.657e-17 0.29
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.294e-17 0.44
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 4.933e-17 0.33
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.11e-16 0.44
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.11e-16 0.39
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.11e-16 0.37
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 3.331e-16 0.34
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.441e-16 0.40
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 6.661e-16 0.34
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1.221e-15 0.44
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.22e-15 0.33
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 2.331e-15 0.43
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.554e-15 0.36
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.887e-15 0.36
ATM_HUMAN ATM Serine-protein kinase ATM 6.661e-15 0.33
ATS1_HUMAN ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1 7.438e-15 0.28
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.61e-14 0.34
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 1.91e-14 0.54
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.987e-14 0.32
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.52e-14 0.30
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 5.429e-14 0.31
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 8.349e-14 0.38
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.297e-13 0.40
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.659e-13 0.36
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 2.965e-13 0.32
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 4.133e-13 0.34
RON_HUMAN MST1R Macrophage-stimulating protein receptor 5.811e-13 0.34
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 6.861e-13 0.32
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 6.918e-13 0.44
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 8.952e-13 0.34
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 9.565e-13 0.30
AURKA_HUMAN AURKA Aurora kinase A 9.638e-13 0.43
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 1.212e-12 0.34
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.304e-12 0.34
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.934e-12 0.38
SHH_MOUSE Shh Sonic hedgehog protein 2.969e-12 0.31
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.988e-12 0.40
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.412e-12 0.34
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 5e-12 0.31
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 1.142e-11 0.34
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.164e-11 0.30
TERT_HUMAN TERT Telomerase reverse transcriptase 1.869e-11 0.33
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 2.36e-11 0.31
PA21B_HUMAN PLA2G1B Phospholipase A2 3.2e-11 0.53
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 3.382e-11 0.29
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 4.351e-11 0.31
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 4.811e-11 0.34
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 5.926e-11 0.33
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 6.267e-11 0.37
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 6.803e-11 0.34
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 7.429e-11 0.34
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 7.585e-11 0.34
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 8.528e-11 0.35
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 1.065e-10 0.38
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.791e-10 0.33
TSHR_HUMAN TSHR Thyrotropin receptor 2.119e-10 0.30
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 2.159e-10 0.36
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.288e-10 0.34
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 2.435e-10 0.30
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 3.982e-10 0.34
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 5.005e-10 0.43
LIPC_HUMAN LIPC Hepatic triacylglycerol lipase 5.505e-10 0.32
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 7.159e-10 0.34
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.086e-09 0.34
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1.086e-09 0.34
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.326e-09 0.34
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.506e-09 0.35
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.688e-09 0.37
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.724e-09 0.34
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 1.983e-09 0.32
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.983e-09 0.32
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.669e-09 0.34
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.14e-09 0.34
MYO3A_HUMAN MYO3A Myosin-IIIa 4.14e-09 0.34
KLK6_HUMAN KLK6 Kallikrein-6 4.579e-09 0.32
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 5.338e-09 0.34
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 5.359e-09 0.30
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 7.375e-09 0.30
TXK_HUMAN TXK Tyrosine-protein kinase TXK 7.625e-09 0.34
ACES_ELEEL ache Acetylcholinesterase 8.001e-09 0.34
CTRO_HUMAN CIT Citron Rho-interacting kinase 8.725e-09 0.34
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 8.725e-09 0.34
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 8.725e-09 0.34
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 9.992e-09 0.43
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.117e-08 0.34
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.117e-08 0.34
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 1.117e-08 0.34
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.117e-08 0.34
MYO3B_HUMAN MYO3B Myosin-IIIb 1.117e-08 0.34
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 1.139e-08 0.31
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 1.5e-08 0.40
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.724e-08 0.30
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.755e-08 0.34
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.755e-08 0.34
AURKB_HUMAN AURKB Aurora kinase B 1.818e-08 0.43
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.994e-08 0.34
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 2.235e-08 0.34
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.365e-08 0.33
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.432e-08 0.34
TEC_HUMAN TEC Tyrosine-protein kinase Tec 2.701e-08 0.34
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.569e-08 0.36
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 4.379e-08 0.44
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 4.4e-08 0.44
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 4.79e-08 0.28
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 5.837e-08 0.34
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 7.158e-08 0.34
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 7.584e-08 0.32
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 7.689e-08 0.34
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.106e-07 0.30
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.173e-07 0.34
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.173e-07 0.34
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.321e-07 0.34
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 1.64e-07 0.33
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 1.67e-07 0.34
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 2.135e-07 0.34
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 2.202e-07 0.34
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 2.764e-07 0.33
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.893e-07 0.43
LIPE_HUMAN LIPG Endothelial lipase 3.371e-07 0.32
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.901e-07 0.34
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.092e-07 0.29
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 4.29e-07 0.34
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 5.148e-07 0.38
TNFA_HUMAN TNF Tumor necrosis factor 5.353e-07 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.648e-07 0.43
INSRR_HUMAN INSRR Insulin receptor-related protein 6.577e-07 0.34
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 6.577e-07 0.34
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 6.577e-07 0.34
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 7.453e-07 0.32
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 7.495e-07 0.34
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 7.718e-07 0.34
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 7.826e-07 0.35
GPR55_HUMAN GPR55 G-protein coupled receptor 55 8.314e-07 0.41
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 8.344e-07 0.32
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 8.469e-07 0.44
RCE1_YEAST RCE1 CAAX prenyl protease 2 8.806e-07 0.32
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 9.028e-07 0.34
PRIO_SHEEP PRNP Major prion protein 9.501e-07 0.31
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.062e-06 0.34
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.062e-06 0.34
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 1.062e-06 0.34
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.068e-06 0.38
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 1.214e-06 0.30
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.347e-06 0.33
GAK_HUMAN GAK Cyclin-G-associated kinase 1.374e-06 0.32
V2R_RAT Avpr2 Vasopressin V2 receptor 1.392e-06 0.30
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 1.443e-06 0.30
PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.453e-06 0.29
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 1.493e-06 0.36
HSF1_MOUSE Hsf1 Heat shock factor protein 1 1.503e-06 0.39
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.652e-06 0.34
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.652e-06 0.34
LUCI_PHOPY Luciferin 4-monooxygenase 1.95e-06 0.37
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 2.359e-06 0.32
CHLE_HORSE BCHE Cholinesterase 2.441e-06 0.32
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.486e-06 0.34
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.486e-06 0.34
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 2.609e-06 0.29
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.965e-06 0.34
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 3.275e-06 0.34
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 3.633e-06 0.34
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 3.633e-06 0.34
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 3.633e-06 0.34
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.71e-06 0.29
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 4.538e-06 0.41
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 5.155e-06 0.29
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.174e-06 0.34
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 5.174e-06 0.34
OX1R_HUMAN HCRTR1 Orexin receptor type 1 6.176e-06 0.38
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 6.246e-06 0.34
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 6.287e-06 0.35
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 6.571e-06 0.34
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 6.803e-06 0.41
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 7.212e-06 0.34
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 7.715e-06 0.34
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 8.13e-06 0.38
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 9.091e-06 0.37