Results of Job: search_481231bf-038f-47de-82b7-e4b6db1e49ba

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 3.722e-157 0.57
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 2.553e-86 0.47
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.342e-83 0.37
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.779e-79 0.43
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 5.322e-71 0.36
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 7.044e-68 0.38
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.344e-67 0.39
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 4.637e-65 0.38
MET_HUMAN MET Hepatocyte growth factor receptor 1.466e-54 0.42
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 6.864e-52 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.793e-44 0.40
ATS1_HUMAN ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1 9.944e-44 0.29
Q8IL11_PLAF7 M17 leucyl aminopeptidase 3.416e-43 0.42
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 3.247e-42 0.33
TLR4_MOUSE Tlr4 Toll-like receptor 4 3.732e-39 0.36
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.382e-38 0.42
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 3.039e-38 0.34
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 4.084e-38 0.43
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 3.56e-37 0.29
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 3.15e-36 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.387e-36 0.39
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.471e-34 0.36
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.076e-33 0.40
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.55e-33 0.39
PRIO_HUMAN PRNP Major prion protein 4.651e-33 0.37
HDAC6_HUMAN HDAC6 Histone deacetylase 6 6.375e-32 0.39
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 7.917e-31 0.32
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 1.487e-29 0.31
SHH_MOUSE Shh Sonic hedgehog protein 1.491e-29 0.34
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 5.867e-29 0.38
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 7.803e-28 0.30
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.694e-26 0.32
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 2.669e-26 0.32
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 6.975e-26 0.35
ATM_HUMAN ATM Serine-protein kinase ATM 1.141e-25 0.32
Q93EK7_NEIME lgtC LgtC 2.28e-25 0.29
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.771e-25 0.39
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 9.049e-25 0.32
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.804e-24 0.36
KC1D_RAT Csnk1d Casein kinase I isoform delta 2.08e-24 0.38
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.715e-24 0.36
AUKBA_XENLA aurkb-a Aurora kinase B-A 4.287e-24 0.39
EGFR_HUMAN EGFR Epidermal growth factor receptor 8.801e-24 0.40
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 1.076e-23 0.37
TLR4_HUMAN TLR4 Toll-like receptor 4 3.545e-22 0.36
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 7.015e-22 0.31
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 8.638e-22 0.44
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 6.654e-21 0.33
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 7.165e-21 0.38
LIPL_HUMAN LPL Lipoprotein lipase 1.372e-18 0.29
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.254e-18 0.34
PRIO_SHEEP PRNP Major prion protein 3.406e-18 0.31
O31272_9GAMM imiS Beta-lactamase 4.994e-18 0.29
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.412e-18 0.47
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.115e-17 0.34
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.365e-17 0.36
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.625e-17 0.47
TSHR_HUMAN TSHR Thyrotropin receptor 1.838e-17 0.32
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 4.764e-17 0.43
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.11e-16 0.42
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.22e-16 0.38
HPSE_HUMAN HPSE Heparanase 2.22e-16 0.36
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 3.331e-16 0.31
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 4.441e-16 0.31
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 7.772e-16 0.31
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 1.332e-15 0.45
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.443e-15 0.44
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 4.885e-15 0.38
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 5.884e-15 0.32
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.066e-14 0.33
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.288e-14 0.36
HDAC1_MOUSE Hdac1 Histone deacetylase 1 5.296e-14 0.30
Q38C41_TRYB2 Phosphotransferase 5.44e-14 0.33
MET_MOUSE Met Hepatocyte growth factor receptor 7.727e-14 0.30
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.03e-13 0.37
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.088e-13 0.34
AURKA_HUMAN AURKA Aurora kinase A 1.2e-13 0.43
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.638e-13 0.35
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.306e-13 0.31
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.48e-13 0.37
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 3.03e-13 0.37
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.026e-13 0.34
PA21B_HUMAN PLA2G1B Phospholipase A2 5.398e-13 0.45
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 6.325e-13 0.28
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 6.588e-13 0.28
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.627e-12 0.36
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 2.903e-12 0.29
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 3.132e-12 0.29
HDAC9_HUMAN HDAC9 Histone deacetylase 9 3.273e-12 0.31
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 3.328e-12 0.36
RON_HUMAN MST1R Macrophage-stimulating protein receptor 3.679e-12 0.38
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 3.739e-12 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 4.101e-12 0.38
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.205e-12 0.34
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.956e-12 0.33
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.14e-11 0.38
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.425e-11 0.31
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 1.482e-11 0.28
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 2.29e-11 0.36
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 2.602e-11 0.33
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 3.371e-11 0.31
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 5.659e-11 0.29
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 8.715e-11 0.32
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 9.841e-11 0.37
AURKB_HUMAN AURKB Aurora kinase B 1.187e-10 0.43
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.193e-10 0.39
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.222e-10 0.31
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 1.444e-10 0.28
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.479e-10 0.28
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.321e-10 0.36
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.568e-10 0.34
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 3.529e-10 0.34
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 3.721e-10 0.38
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 5.319e-10 0.44
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 5.929e-10 0.40
MEP50_HUMAN WDR77 Methylosome protein 50 1.314e-09 0.33
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.38e-09 0.30
C3SLN3_ECOLX gyrB DNA gyrase subunit B 1.458e-09 0.30
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.649e-09 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 2.312e-09 0.35
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 2.564e-09 0.36
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.653e-09 0.34
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 3.697e-09 0.33
LCK_HUMAN LCK Tyrosine-protein kinase Lck 4.969e-09 0.39
SMO_HUMAN SMO Smoothened homolog 5.031e-09 0.31
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 5.748e-09 0.34
KLK7_HUMAN KLK7 Kallikrein-7 5.785e-09 0.37
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 7.265e-09 0.34
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 8.5e-09 0.35
ACES_ELEEL ache Acetylcholinesterase 9.81e-09 0.32
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.117e-08 0.36
HDAC5_HUMAN HDAC5 Histone deacetylase 5 1.176e-08 0.31
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.506e-08 0.30
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.828e-08 0.36
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 2.527e-08 0.35
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 2.884e-08 0.32
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.116e-08 0.38
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.252e-08 0.34
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 4.164e-08 0.31
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 4.429e-08 0.30
HDAC3_HUMAN HDAC3 Histone deacetylase 3 4.835e-08 0.35
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.244e-08 0.29
FA7_HUMAN F7 Coagulation factor VII 8.297e-08 0.32
XBP1_HUMAN XBP1 X-box-binding protein 1 8.48e-08 0.36
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 8.937e-08 0.30
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 9.363e-08 0.41
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.332e-07 0.42
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.506e-07 0.34
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.743e-07 0.30
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.812e-07 0.29
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 2.954e-07 0.33
HSF1_MOUSE Hsf1 Heat shock factor protein 1 3.204e-07 0.41
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 3.403e-07 0.33
RECA_MYCTU recA Protein RecA 3.59e-07 0.40
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 3.642e-07 0.29
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 4.919e-07 0.35
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 6.098e-07 0.36
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 6.925e-07 0.31
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 6.966e-07 0.36
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.166e-06 0.32
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.21e-06 0.28
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.245e-06 0.34
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 1.593e-06 0.36
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.818e-06 0.29
KLK5_HUMAN KLK5 Kallikrein-5 2.849e-06 0.29
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 2.876e-06 0.36
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 3.082e-06 0.28
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 3.109e-06 0.29
KHK_HUMAN KHK Ketohexokinase 3.364e-06 0.31
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 3.547e-06 0.42
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.718e-06 0.36
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 3.995e-06 0.35
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 4.511e-06 0.32
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 4.73e-06 0.31
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.957e-06 0.28
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.153e-06 0.33
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 5.23e-06 0.33
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 5.782e-06 0.32
DPOL_VACCW POL DNA polymerase 5.785e-06 0.29
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 6.034e-06 0.36
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 8.09e-06 0.28
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 9.178e-06 0.39
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 9.409e-06 0.30