Results of Job: search_487a2f07-f6cf-4e22-8882-73064cfeff80

Query Target Key Target Name Description P-Value MaxTC

Sotagliflozin

SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 0 1.00
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 2.25e-118 1.00
SC5A2_MOUSE Slc5a2 Sodium/glucose cotransporter 2 3.865e-193 0.77
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 1.838e-76 0.73
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 6.659e-58 0.73
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 2.252e-29 0.73
Q9QXI6_MOUSE Slc5a1 SGLT1 protein 5.329e-15 0.33
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.846e-13 0.28
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 4.846e-13 0.28
KLK1_HUMAN KLK1 Kallikrein-1 3.794e-09 0.32
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 7.69e-08 0.33
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.197e-07 0.30
KLKB1_HUMAN KLKB1 Plasma kallikrein 8.61e-07 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.315e-06 0.30

Tazemetostat

EZH2_HUMAN EZH2 Histone-lysine N-methyltransferase EZH2 0 1.00
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 6.483e-136 1.00
AEBP2_HUMAN AEBP2 Zinc finger protein AEBP2 3.313e-135 1.00
RBBP4_HUMAN RBBP4 Histone-binding protein RBBP4 3.668e-112 1.00
SUZ12_HUMAN SUZ12 Polycomb protein SUZ12 2.004e-77 1.00
EED_HUMAN EED Polycomb protein EED 4.131e-13 1.00
DPOL_HHV11 DNA polymerase catalytic subunit 4.071e-31 0.36
DPOL_VZVD DNA polymerase catalytic subunit 4.071e-31 0.36
Q9X688_CAUVI cckA Cell cycle histidine kinase CckA 1.131e-25 0.32
LPXC_ECOLI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.509e-20 0.31
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 3.254e-19 0.30
C6ARS9_RHILS lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.576e-18 0.29
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.309e-08 0.40
DPO3_BACSU polC DNA polymerase III PolC-type 1.757e-08 0.30
TRAP1_HUMAN TRAP1 Heat shock protein 75 kDa, mitochondrial 2.534e-08 0.36
BTK_MOUSE Btk Tyrosine-protein kinase BTK 2.711e-08 0.35
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 7.84e-08 0.31
DPOL_HCMVA UL54 DNA polymerase catalytic subunit 1.247e-07 0.36
FA10_RABIT F10 Coagulation factor X 6.313e-07 0.31
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.024e-06 0.36
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.024e-06 0.36
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.029e-06 0.31
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.821e-06 0.37
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.567e-06 0.36
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 4.606e-06 0.35
MMP13_MOUSE Mmp13 Collagenase 3 5.87e-06 0.30
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 5.925e-06 0.32
ENPL_CANLF HSP90B1 Endoplasmin 6.825e-06 0.32

Zoliflodacin

GYRA_ECOLI gyrA DNA gyrase subunit A 0 1.00

Dinoprost

PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 1.641e-180 1.00
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 1.149e-170 1.00
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.405e-131 1.00
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 8.772e-130 1.00
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 3.769e-119 1.00
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 4.242e-93 1.00
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 2.824e-58 1.00
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.97e-46 1.00
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.893e-44 1.00
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.688e-40 1.00
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 4.471e-33 1.00
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.11e-16 1.00
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 5.728e-75 0.67
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 2.057e-59 0.67
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 7.331e-49 0.67
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 8.257e-45 0.67
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.263e-41 0.67
CERT_HUMAN CERT1 Ceramide transfer protein 2.095e-36 0.29
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 6.356e-31 0.43
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.295e-27 0.32
PI2R_HUMAN PTGIR Prostacyclin receptor 1.012e-26 0.67
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 2.526e-24 0.31
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 3.737e-24 0.32
PE2R4_RABIT PTGER4 Prostaglandin E2 receptor EP4 subtype 2.847e-23 0.29
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 6.364e-22 0.67
CNR1_RAT Cnr1 Cannabinoid receptor 1 1.884e-21 0.40
Q6UB75_PIG Group VII phospholipase A2 9.633e-21 0.31
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 2.743e-19 0.67
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 3.618e-19 0.67
TA2R_RAT Tbxa2r Thromboxane A2 receptor 3.827e-19 0.67
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 4.441e-16 0.37
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 3.508e-14 0.34
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.109e-13 0.31
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.585e-13 0.41
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.761e-12 0.31
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 2.717e-12 0.41
LYAM3_HUMAN SELP P-selectin 1.053e-11 0.30
MGLL_RAT Mgll Monoglyceride lipase 1.421e-11 0.34
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.859e-11 0.40
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 1.25e-10 0.31
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 5.569e-09 0.34
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 1.236e-08 0.47
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 1.179e-07 0.36
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 2.848e-07 0.34
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.343e-06 0.31
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 2.837e-06 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.015e-06 0.38
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.26e-06 0.33

Macimorelin

GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 1.103e-105 1.00
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.851e-205 0.45
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 4.423e-161 0.44
MC5R_MOUSE Mc5r Melanocortin receptor 5 6.809e-146 0.43
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.947e-135 0.47
CD36_RAT Cd36 Platelet glycoprotein 4 1.036e-124 0.41
MMP11_MOUSE Mmp11 Stromelysin-3 1.916e-122 0.39
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.644e-121 0.43
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 2.001e-120 0.38
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.299e-117 0.43
EDNRB_RAT Ednrb Endothelin receptor type B 3.09e-110 0.42
MC3R_MOUSE Mc3r Melanocortin receptor 3 4.902e-105 0.42
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 4.396e-103 0.45
CCKAR_RAT Cckar Cholecystokinin receptor type A 1.414e-102 0.46
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 1.117e-99 0.37
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 1.796e-99 0.37
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 2.082e-98 0.45
NMBR_HUMAN NMBR Neuromedin-B receptor 1.742e-97 0.48
EDNRA_PIG EDNRA Endothelin-1 receptor 2.323e-86 0.39
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 4.262e-84 0.41
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 2.069e-80 0.48
MC3R_HUMAN MC3R Melanocortin receptor 3 1.105e-76 0.45
EDNRA_MOUSE Ednra Endothelin-1 receptor 8.827e-76 0.41
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.073e-75 0.43
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 6.876e-73 0.42
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 3.309e-72 0.32
KISSR_HUMAN KISS1R KiSS-1 receptor 7.793e-72 0.37
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 1.605e-69 0.55
MMP11_HUMAN MMP11 Stromelysin-3 2.958e-69 0.36
MC4R_HUMAN MC4R Melanocortin receptor 4 1.211e-62 0.45
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.363e-60 0.40
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 8.088e-59 0.41
NEP_RABIT MME Neprilysin 4.187e-54 0.47
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 5.438e-53 0.33
NMBR_RAT Nmbr Neuromedin-B receptor 9.243e-52 0.33
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 3.327e-51 0.52
ECE1_RAT Ece1 Endothelin-converting enzyme 1 7.305e-51 0.46
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 4.302e-50 0.47
RUVB1_HUMAN RUVBL1 RuvB-like 1 2.356e-47 0.38
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 4.085e-46 0.44
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 1.542e-45 0.36
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.266e-45 0.43
IL1RA_MOUSE Il1rn Interleukin-1 receptor antagonist protein 7.532e-45 0.36
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 7.003e-44 0.48
NK1R_HUMAN TACR1 Substance-P receptor 1.385e-43 0.47
ACE_RAT Ace Angiotensin-converting enzyme 1.379e-42 0.47
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.88e-42 0.33
MMP8_HUMAN MMP8 Neutrophil collagenase 1.172e-41 0.48
GRPR_RAT Grpr Gastrin-releasing peptide receptor 1.226e-41 0.32
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.096e-40 0.48
SURA_ECOLI surA Chaperone SurA 4.314e-40 0.32
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 4.488e-39 0.46
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 5.2e-39 0.41
NK1R_CAVPO TACR1 Substance-P receptor 5.935e-39 0.48
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.778e-38 0.48
G1FEK8_9CALI Protease 1.708e-37 0.30
I1U3K2_9CALI POL Nonstructural polyprotein 1.708e-37 0.30
NK1R_RAT Tacr1 Substance-P receptor 1.284e-36 0.39
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 2.508e-36 0.31
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 8.575e-35 0.35
CP125_MYCTU cyp125 Steroid C26-monooxygenase 2.789e-33 0.41
NK1R_MOUSE Tacr1 Substance-P receptor 1.948e-32 0.32
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.642e-30 0.42
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 1.548e-29 0.37
THER_BACTH npr Thermolysin 1.889e-29 0.47
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 6.609e-29 0.42
MMP8_RAT Mmp8 Neutrophil collagenase 2.067e-28 0.48
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 4.416e-28 0.39
ELAS_PSEAE lasB Elastase 5.567e-28 0.49
NK2R_MESAU TACR2 Substance-K receptor 7.511e-28 0.46
CATL1_BOVIN CTSL Cathepsin L1 1.135e-27 0.49
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.665e-27 0.36
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 3.19e-27 0.44
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.069e-26 0.48
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.108e-26 0.39
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 4.251e-26 0.44
OPRM_RAT Oprm1 Mu-type opioid receptor 8.007e-26 0.39
FSHR_RAT Fshr Follicle-stimulating hormone receptor 4.725e-25 0.31
ACE_HUMAN ACE Angiotensin-converting enzyme 1.058e-24 0.51
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 2.701e-24 0.47
MMP1_HUMAN MMP1 Interstitial collagenase 2.969e-24 0.49
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 6.209e-24 0.37
TYRO_HUMAN TYR Tyrosinase 1.765e-23 0.40
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.831e-23 0.38
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.589e-23 0.47
PLMN_BOVIN PLG Plasminogen 8.349e-23 0.29
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 8.598e-23 0.40
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 1.186e-22 0.39
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.851e-22 0.39
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.754e-21 0.38
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 3.13e-21 0.41
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 6.64e-20 0.44
HDAC2_HUMAN HDAC2 Histone deacetylase 2 9.135e-20 0.41
CATL1_HUMAN CTSL Cathepsin L1 9.214e-20 0.49
GRIA1_RAT Gria1 Glutamate receptor 1 1.174e-19 0.38
VM1B1_BOTAS Snake venom metalloproteinase BaP1 2.749e-18 0.29
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 8.52e-18 0.28
MMP7_HUMAN MMP7 Matrilysin 1.32e-17 0.44
BODG_PSESK Gamma-butyrobetaine dioxygenase 1.405e-17 0.39
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.11e-16 0.40
IDE_HUMAN IDE Insulin-degrading enzyme 1.11e-16 0.36
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.11e-16 0.35
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.22e-16 0.41
RENI_RAT Ren1 Renin 2.22e-16 0.41
OPRD_RAT Oprd1 Delta-type opioid receptor 3.331e-16 0.39
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 4.441e-16 0.32
CAN1_RAT Capn1 Calpain-1 catalytic subunit 9.992e-16 0.42
PAPA1_CARPA Papain 1.665e-15 0.49
HES1_MOUSE Hes1 Transcription factor HES-1 4.441e-15 0.29
MC5R_HUMAN MC5R Melanocortin receptor 5 4.663e-15 0.38
EDNRB_HUMAN EDNRB Endothelin receptor type B 9.437e-15 0.42
NEP_HUMAN MME Neprilysin 1.066e-14 0.43
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 1.188e-14 0.39
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.632e-14 0.32
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 2.165e-14 0.36
NEP_PIG MME Neprilysin 2.609e-14 0.43
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 3.009e-14 0.32
EDNRA_RAT Ednra Endothelin-1 receptor 3.331e-14 0.38
CATB_HUMAN CTSB Cathepsin B 3.342e-14 0.44
CASP9_HUMAN CASP9 Caspase-9 6.173e-14 0.37
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 9.392e-14 0.40
NK2R_RABIT TACR2 Substance-K receptor 1.039e-13 0.38
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.1e-13 0.49
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 2.904e-13 0.48
NRP1_RAT Nrp1 Neuropilin-1 3.386e-13 0.32
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 3.417e-13 0.32
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 3.478e-13 0.37
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 7.172e-13 0.37
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 9.004e-13 0.37
CASPA_HUMAN CASP10 Caspase-10 1.355e-12 0.37
MMP9_RAT Mmp9 Matrix metalloproteinase-9 1.708e-12 0.48
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 2.632e-12 0.31
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 2.902e-12 0.36
NK3R_CAVPO TACR3 Neuromedin-K receptor 3.775e-12 0.30
MTSI_SPISQ sssIM CPG DNA methylase 4.506e-12 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.929e-12 0.41
POLG_DEN26 Genome polyprotein 6.448e-12 0.38
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 1.437e-11 0.28
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.483e-11 0.51
NEP_RAT Mme Neprilysin 1.529e-11 0.44
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 2.708e-11 0.30
NK3R_HUMAN TACR3 Neuromedin-K receptor 3.586e-11 0.51
NK2R_RAT Tacr2 Substance-K receptor 4.139e-11 0.38
MMP25_HUMAN MMP25 Matrix metalloproteinase-25 5.054e-11 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.441e-11 0.51
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 5.585e-11 0.44
EDNRB_PIG EDNRB Endothelin receptor type B 6.302e-11 0.41
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 6.772e-11 0.32
TAT_HV1H2 tat Protein Tat 7.054e-11 0.32
AMPN_MOUSE Anpep Aminopeptidase N 7.946e-11 0.29
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 9.798e-11 0.33
MMP3_HUMAN MMP3 Stromelysin-1 3.26e-10 0.49
HEPS_HUMAN HPN Serine protease hepsin 3.689e-10 0.40
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 3.856e-10 0.39
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.152e-10 0.46
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 4.513e-10 0.37
OPRM_MOUSE Oprm1 Mu-type opioid receptor 5.419e-10 0.38
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 5.489e-10 0.34
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 7.282e-10 0.35
RENI_HUMAN REN Renin 1.262e-09 0.41
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.272e-09 0.35
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 2.028e-09 0.31
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.916e-09 0.41
NK2R_HUMAN TACR2 Substance-K receptor 2.946e-09 0.40
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.224e-09 0.31
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 5.382e-09 0.44
CATB_BOVIN CTSB Cathepsin B 6.28e-09 0.35
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 7.565e-09 0.31
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 7.565e-09 0.31
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 1.053e-08 0.44
KPCG_HUMAN PRKCG Protein kinase C gamma type 1.225e-08 0.31
UR2R_RAT Uts2r Urotensin-2 receptor 1.286e-08 0.43
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 1.344e-08 0.37
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.713e-08 0.32
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.921e-08 0.37
CBX7_HUMAN CBX7 Chromobox protein homolog 7 1.959e-08 0.42
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 2.684e-08 0.42
CHLE_HUMAN BCHE Cholinesterase 2.801e-08 0.39
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.878e-08 0.41
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.999e-08 0.38
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 3.922e-08 0.40
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 4.514e-08 0.31
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 4.514e-08 0.31
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 4.561e-08 0.37
PDIA1_HUMAN P4HB Protein disulfide-isomerase 5.166e-08 0.39
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 5.395e-08 0.29
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 5.395e-08 0.29
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 5.395e-08 0.29
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 5.395e-08 0.29
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 5.395e-08 0.29
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 5.395e-08 0.29
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 5.395e-08 0.29
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 5.395e-08 0.29
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 5.395e-08 0.29
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 5.395e-08 0.29
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 5.395e-08 0.29
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 5.395e-08 0.29
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 5.395e-08 0.29
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 6.15e-08 0.31
SPRE_HUMAN SPR Sepiapterin reductase 6.44e-08 0.29
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 7.259e-08 0.43
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 8.269e-08 0.31
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 8.591e-08 0.41
Q91H74_9FLAV Genome polyprotein 8.6e-08 0.43
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 9.501e-08 0.29
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.156e-07 0.46
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.596e-07 0.35
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 1.952e-07 0.33
CASP5_HUMAN CASP5 Caspase-5 1.96e-07 0.37
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 2.155e-07 0.37
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.061e-07 0.31
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 5.151e-07 0.32
NK3R_RAT Tacr3 Neuromedin-K receptor 5.41e-07 0.36
MCR_HUMAN NR3C2 Mineralocorticoid receptor 6.232e-07 0.40
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 6.37e-07 0.38
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 6.418e-07 0.32
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 8.66e-07 0.41
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.13e-06 0.47
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 1.354e-06 0.31
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 1.354e-06 0.31
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.59e-06 0.31
TYTR_TRYCR TPR Trypanothione reductase 1.733e-06 0.38
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.746e-06 0.30
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.792e-06 0.46
CASP4_HUMAN CASP4 Caspase-4 1.83e-06 0.37
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 1.973e-06 0.33
ACES_HUMAN ACHE Acetylcholinesterase 3.309e-06 0.40
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 5.36e-06 0.35
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 6.029e-06 0.40
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 8.213e-06 0.30
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 9.039e-06 0.33

Benserazide

POLG_CXB3N Genome polyprotein 1.204e-95 1.00
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 3.347e-06 1.00
MEX5_CAEEL mex-5 Zinc finger protein mex-5 8.069e-05 1.00
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 0.0005651 1.00
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 0.0006262 1.00
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 1.381e-38 0.31
TY3H_RAT Th Tyrosine 3-monooxygenase 7.142e-37 0.29
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 8.139e-28 0.38
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 6.932e-21 0.30
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.523e-18 0.29
TY3H_HUMAN TH Tyrosine 3-monooxygenase 2.139e-18 0.29
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 4.441e-15 0.29
NEP_MOUSE Mme Neprilysin 3.922e-13 0.29
CSK_HUMAN CSK Tyrosine-protein kinase CSK 5.746e-12 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.813e-08 0.28
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 4.51e-08 0.28
GRIA1_RAT Gria1 Glutamate receptor 1 6.811e-08 0.29
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.254e-06 0.29

Levosalbutamol

ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.146e-86 1.00
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 5.019e-94 0.72
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.179e-60 0.46
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 6.007e-52 0.48
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 5.023e-46 0.37
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 5.023e-46 0.37
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 9.011e-45 0.65
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.986e-40 0.45
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.69e-35 0.45
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.152e-31 0.45
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 2.277e-23 0.37
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.482e-21 0.47
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.581e-20 0.45
G3HDX1_CRIGR Alpha-1B adrenergic receptor 5.806e-19 0.36
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.643e-12 0.45
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.601e-11 0.37
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 9.543e-11 0.45
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.443e-08 0.40

Fenpropidin

B6TK44_MAIZE Cycloeucalenol cycloisomerase 3.787e-81 1.00
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 1.937e-73 1.00
Q2TU57_MAIZE Sterol-8,7-isomerase 1.79e-56 1.00
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.948e-36 0.29
HRH3_HUMAN HRH3 Histamine H3 receptor 4.63e-26 0.48
S13A5_HUMAN SLC13A5 Solute carrier family 13 member 5 6.643e-18 0.29
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.055e-14 0.61
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 3.193e-11 0.41
HRH3_RAT Hrh3 Histamine H3 receptor 1.266e-10 0.40
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 5.287e-10 0.37
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 4.894e-09 0.41
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 6.276e-09 0.42
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 7.149e-09 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.452e-08 0.38
ERG2_YEAST ERG2 C-8 sterol isomerase 4.897e-08 0.61
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 1.227e-07 0.28
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.1e-07 0.61
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.815e-07 0.61
HRH3_MOUSE Hrh3 Histamine H3 receptor 7.082e-07 0.34
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 2.33e-06 0.29
DRD2_MOUSE Drd2 D(2) dopamine receptor 9.031e-06 0.33
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.96e-06 0.32

Trifarotene

RARB_HUMAN RARB Retinoic acid receptor beta 1.435e-69 1.00
RARG_HUMAN RARG Retinoic acid receptor gamma 1.364e-63 1.00
RARA_HUMAN RARA Retinoic acid receptor alpha 1.176e-59 1.00
LIPL_BOVIN LPL Lipoprotein lipase 8.244e-54 0.32
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 9.285e-44 0.33
RET4_HUMAN RBP4 Retinol-binding protein 4 5.072e-23 0.38
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 2.179e-19 0.30
CATS_MOUSE Ctss Cathepsin S 2.22e-16 0.31
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 1.11e-15 0.36
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.654e-14 0.33
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 3.209e-14 0.32
HPSE_HUMAN HPSE Heparanase 5.436e-12 0.34
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 9.995e-12 0.30
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 4.982e-11 0.40
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 8.4e-11 0.29
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.719e-10 0.30
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 3.229e-10 0.34
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.322e-08 0.29
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.394e-08 0.33
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 5.06e-07 0.30
BRD2_HUMAN BRD2 Bromodomain-containing protein 2 6.788e-07 0.32
BRD3_HUMAN BRD3 Bromodomain-containing protein 3 1.071e-06 0.32
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 1.338e-06 0.29
PB1_HUMAN PBRM1 Protein polybromo-1 2.222e-06 0.30
Q70GC6_9HEPC NS5B RNA-directed RNA polymerase 3.213e-06 0.29

Quizartinib

FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 7.541e-54 1.00
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 6.281e-27 1.00
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 2.639e-24 1.00
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 7.777e-24 1.00
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 9.54e-24 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 7.038e-20 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 5.584e-19 1.00
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 6.464e-19 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.272e-18 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.11e-16 1.00
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1.11e-16 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 2.22e-16 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.331e-16 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.331e-15 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.053e-14 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.386e-14 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 6.878e-13 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 7.979e-13 1.00
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 2.182e-12 1.00
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 9.379e-12 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.239e-11 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 1.756e-10 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 2.994e-10 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 5.535e-10 1.00
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1.368e-09 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 2.199e-09 1.00
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 2.57e-09 1.00
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 5.405e-09 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 5.586e-09 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 6.289e-09 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.643e-08 1.00
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.318e-07 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.102e-06 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1.344e-06 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1.738e-06 1.00
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1.204e-05 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.91e-05 1.00
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 9.203e-05 1.00
MET_CANLF MET Hepatocyte growth factor receptor 2.019e-49 0.34
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 5.29e-40 0.32
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 4.387e-38 0.41
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 9.13e-30 0.41
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 5.244e-26 0.38
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 3.559e-24 0.43
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 4.99e-24 0.32
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 5.033e-23 0.47
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 2.056e-22 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 5.672e-20 0.39
USP9X_HUMAN USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 5.758e-20 0.32
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 1.132e-19 0.31
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 6.368e-19 0.44
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.918e-18 0.29
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.204e-18 0.47
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 3.404e-18 0.31
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.089e-17 0.56
NORA_STAAU norA Quinolone resistance protein NorA 5.308e-17 0.29
AURKB_HUMAN AURKB Aurora kinase B 2.22e-16 0.52
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 5.551e-16 0.38
AURKA_HUMAN AURKA Aurora kinase A 6.661e-16 0.62
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 8.882e-16 0.40
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 9.992e-16 0.37
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 9.992e-16 0.37
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 9.992e-16 0.37
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 5.551e-15 0.38
ROCK2_RAT Rock2 Rho-associated protein kinase 2 6.928e-14 0.28
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 1.8e-13 0.37
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 4.962e-13 0.43
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 7.272e-13 0.34
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 1.608e-12 0.31
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.699e-12 0.33
CBP_HUMAN CREBBP CREB-binding protein 2.173e-12 0.34
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 1.079e-11 0.33
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 2.411e-11 0.36
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.413e-11 0.37
NK2R_HUMAN TACR2 Substance-K receptor 2.787e-10 0.33
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 4.675e-10 0.36
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 7.541e-10 0.29
CCNC_HUMAN CCNC Cyclin-C 8.766e-10 0.56
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 9.069e-10 0.28
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.096e-09 0.43
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.46e-09 0.37
ACRO_HUMAN ACR Acrosin 1.952e-09 0.28
PDE6A_HUMAN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 2.669e-09 0.31
CASR_HUMAN CASR Extracellular calcium-sensing receptor 3.121e-09 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 3.543e-09 0.37
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 3.543e-09 0.37
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 4.268e-09 0.28
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 6.174e-09 0.30
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 7.868e-09 0.37
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 8.052e-09 0.56
CTRO_HUMAN CIT Citron Rho-interacting kinase 1.139e-08 0.37
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 1.139e-08 0.37
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.166e-08 0.39
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1.677e-08 0.37
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.269e-08 0.37
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.269e-08 0.37
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 4.629e-08 0.28
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 4.804e-08 0.39
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 7.906e-08 0.37
A5A4K8_RABIT MLNR Motilin receptor 8.934e-08 0.31
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.188e-07 0.28
MYO3A_HUMAN MYO3A Myosin-IIIa 1.188e-07 0.28
FER_HUMAN FER Tyrosine-protein kinase Fer 2.037e-07 0.30
CNR2_HUMAN CNR2 Cannabinoid receptor 2 2.188e-07 0.38
MK13_HUMAN MAPK13 Mitogen-activated protein kinase 13 2.65e-07 0.37
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 2.701e-07 0.28
MYO3B_HUMAN MYO3B Myosin-IIIb 2.701e-07 0.28
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 4.302e-07 0.38
GYRB_MYCSM gyrB DNA gyrase subunit B 5.085e-07 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 7.493e-07 0.35
BLK_HUMAN BLK Tyrosine-protein kinase Blk 7.733e-07 0.37
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 8.337e-07 0.37
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 1.062e-06 0.28
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.105e-06 0.37
HRH3_HUMAN HRH3 Histamine H3 receptor 1.129e-06 0.36
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.184e-06 0.35
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.211e-06 0.32
AURKC_HUMAN AURKC Aurora kinase C 1.859e-06 0.31
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.893e-06 0.28
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 2.233e-06 0.32
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 2.406e-06 0.35
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 2.431e-06 0.33
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 3.189e-06 0.28
MINK1_HUMAN MINK1 Misshapen-like kinase 1 4.03e-06 0.37
HRH3_RAT Hrh3 Histamine H3 receptor 4.826e-06 0.33
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 5.123e-06 0.28
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 5.35e-06 0.33
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 6.678e-06 0.29
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 6.955e-06 0.31
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 7.395e-06 0.29
INSRR_HUMAN INSRR Insulin receptor-related protein 7.898e-06 0.28
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 7.898e-06 0.28
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 8.112e-06 0.37
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 8.827e-06 0.29
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 9.021e-06 0.30
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 9.309e-06 0.47
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 9.902e-06 0.33

Pexidartinib

CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.848e-33 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.624e-09 1.00
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 2.467e-41 0.34
PB2_I34A1 PB2 Polymerase basic protein 2 6.085e-36 0.31
STIM1_HUMAN STIM1 Stromal interaction molecule 1 1.903e-34 0.33
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 2.684e-31 0.33
SYUA_HUMAN SNCA Alpha-synuclein 1.407e-18 0.39
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 8.071e-14 0.38
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 6.555e-12 0.79
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 3.726e-11 0.79
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 1.517e-10 0.31
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 2.466e-09 0.29
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.193e-08 0.79
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 3.012e-08 0.31
CCNT1_HUMAN CCNT1 Cyclin-T1 4.736e-08 0.33
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 6.072e-07 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 8.732e-07 0.79
AVR2B_HUMAN ACVR2B Activin receptor type-2B 1.069e-06 0.31
TLR7_HUMAN TLR7 Toll-like receptor 7 2.073e-06 0.37
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 2.455e-06 0.31
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 2.859e-06 0.31
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 4.399e-06 0.31

Resmetirom

THB_HUMAN THRB Thyroid hormone receptor beta 2.216e-20 1.00
THA_HUMAN THRA Thyroid hormone receptor alpha 4.296e-20 1.00

Oxatomide

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.441e-16 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.329e-15 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 4.135e-08 1.00
PLD1_RAT Pld1 Phospholipase D1 1.79e-100 0.35
RMLC_MYCTO rmlC dTDP-4-dehydrorhamnose 3,5-epimerase 1.407e-96 0.41
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 3.542e-83 0.53
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.51e-70 0.53
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 7.859e-67 0.63
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 1.504e-60 0.34
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 1.504e-60 0.34
PLD2_HUMAN PLD2 Phospholipase D2 2.327e-55 0.37
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 8.165e-55 0.34
PLD1_HUMAN PLD1 Phospholipase D1 3.125e-52 0.37
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.135e-51 0.53
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.917e-43 0.45
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 7.242e-40 0.33
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.836e-37 0.69
HPRK_BACSU hprK HPr kinase/phosphorylase 1.917e-37 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.789e-37 0.33
S6A13_HUMAN SLC6A13 Sodium- and chloride-dependent GABA transporter 2 2.095e-36 0.29
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 4.852e-35 0.69
OPRX_HUMAN OPRL1 Nociceptin receptor 6.523e-33 0.40
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.078e-31 0.51
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 2.034e-30 0.31
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.542e-29 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.151e-27 0.65
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.612e-27 0.37
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 1.437e-26 0.46
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.931e-25 0.40
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 7.81e-23 0.29
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.311e-21 0.33
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.466e-21 0.51
DPO3_BACSU polC DNA polymerase III PolC-type 5.156e-21 0.36
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.848e-20 0.40
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.801e-20 0.40
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.258e-19 0.57
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.716e-18 0.45
OPRM_HUMAN OPRM1 Mu-type opioid receptor 5.208e-18 0.51
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.123e-17 0.53
HRH3_CAVPO HRH3 Histamine H3 receptor 1.627e-17 0.32
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.996e-15 0.65
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 9.104e-15 0.29
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 9.326e-15 0.34
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.166e-14 0.36
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.874e-14 0.45
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 9.093e-14 0.45
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.302e-13 0.51
DRD2_RAT Drd2 D(2) dopamine receptor 2.159e-13 0.51
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 2.804e-13 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.358e-13 0.43
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.471e-13 0.32
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.163e-13 0.41
OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.653e-13 0.45
Q63380_RAT NET Transporter 8.483e-13 0.34
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.327e-12 0.51
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.384e-11 0.51
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.442e-11 0.41
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 2.336e-11 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 3.639e-11 0.51
US28_HCMVA US28 G-protein coupled receptor homolog US28 7.655e-11 0.29
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.553e-10 0.28
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 4.839e-10 0.31
ACES_ELEEL ache Acetylcholinesterase 7.439e-10 0.39
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.338e-09 0.51
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.432e-09 0.41
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.447e-09 0.41
MC4R_HUMAN MC4R Melanocortin receptor 4 2.457e-09 0.35
DRD3_CHLAE DRD3 D(3) dopamine receptor 3.183e-09 0.33
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 5.902e-09 0.34
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 9.96e-09 0.41
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.241e-08 0.32
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.454e-08 0.51
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 2.753e-08 0.45
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 3.719e-08 0.51
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.831e-08 0.34
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 4.104e-08 0.40
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 7.488e-08 0.51
MGLL_HUMAN MGLL Monoglyceride lipase 9.235e-08 0.37
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.273e-08 0.34
MGLL_RAT Mgll Monoglyceride lipase 1.146e-07 0.32
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.489e-07 0.45
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 6.969e-07 0.41
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 8.279e-07 0.31
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 1.25e-06 0.32
DUT_HUMAN DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 1.282e-06 0.34
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.364e-06 0.51
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.097e-06 0.38
MGLL_MOUSE Mgll Monoglyceride lipase 2.592e-06 0.32
THAS_RAT Tbxas1 Thromboxane-A synthase 2.641e-06 0.34
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 2.68e-06 0.33
ACHP_LYMST Acetylcholine-binding protein 2.841e-06 0.36
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 3.021e-06 0.34
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 3.379e-06 0.51
Q9WTR4_RAT Slc6a2 Transporter 3.484e-06 0.40
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 3.969e-06 0.32
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 4.188e-06 0.29
DRD2_CHLAE DRD2 D(2) dopamine receptor 6.24e-06 0.33
DRD4_RAT Drd4 D(4) dopamine receptor 6.346e-06 0.30

Fluindione

LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.266e-05 1.00
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 1.125e-22 0.37
P2RX7_MOUSE P2rx7 P2X purinoceptor 7 8.159e-21 0.59
DUS1_MOUSE Dusp1 Dual specificity protein phosphatase 1 3.462e-20 0.32
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 3.819e-20 0.33
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 6.741e-19 0.30
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 4.33e-15 0.37
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 4.441e-15 0.29
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.774e-15 0.33
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.998e-11 0.30
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 2.791e-09 0.29
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.207e-08 0.44
RCOR1_HUMAN RCOR1 REST corepressor 1 1.383e-08 0.37
STXA_SHIDY stxA Shiga toxin subunit A 2.637e-08 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.327e-07 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.362e-07 0.29
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.507e-06 0.30
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 1.683e-06 0.29
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.7e-06 0.30
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.849e-06 0.29
WDR48_HUMAN WDR48 WD repeat-containing protein 48 3.073e-06 0.44
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 4.483e-06 0.33
OXDA_MOUSE Dao D-amino-acid oxidase 5.379e-06 0.28
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 7.185e-06 0.40
EST1_HUMAN CES1 Liver carboxylesterase 1 9.099e-06 0.38
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 9.988e-06 0.34

Parthenolide

NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 0.00285 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 0.04496 1.00
UB2D3_HUMAN UBE2D3 Ubiquitin-conjugating enzyme E2 D3 3.246e-55 0.35
Q4QYD9_RAT Heat sensitive channel TRPV3 6.588e-43 0.34
MYB_CHICK MYB Transcriptional activator Myb 8.93e-33 0.56
TF65_HUMAN RELA Transcription factor p65 2.665e-21 0.45
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 3.509e-07 0.39

Benperidol

OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 5.214e-205 0.39
PLD1_RAT Pld1 Phospholipase D1 2.197e-120 0.45
PLD1_HUMAN PLD1 Phospholipase D1 2.361e-109 0.45
PLD2_HUMAN PLD2 Phospholipase D2 1.327e-108 0.45
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.674e-95 0.43
DRD4_RAT Drd4 D(4) dopamine receptor 9.343e-73 0.50
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.528e-56 0.52
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.214e-55 0.52
CCR3_RAT Ccr3 C-C chemokine receptor type 3 1.041e-52 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.901e-51 0.49
HRH1_HUMAN HRH1 Histamine H1 receptor 6.073e-49 0.50
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.085e-46 0.60
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 2.28e-46 0.33
DRD2_RAT Drd2 D(2) dopamine receptor 8.259e-46 0.58
DRD1_PIG DRD1 D(1A) dopamine receptor 1.68e-44 0.45
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 5.734e-44 0.38
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.877e-44 0.54
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.738e-40 0.43
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.635e-39 0.43
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 7.749e-39 0.44
5HT2A_MACMU HTR2A 5-hydroxytryptamine receptor 2A 4.536e-38 0.30
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 2.649e-37 0.47
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 4.238e-36 0.65
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 1.827e-35 0.44
DRD5_RAT Drd5 D(1B) dopamine receptor 8.375e-35 0.48
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.197e-34 0.43
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.85e-32 0.65
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.726e-31 0.50
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 2.551e-31 0.48
Q4DCQ3_TRYCC Superoxide dismutase 1.428e-30 0.38
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 2.535e-30 0.47
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.703e-30 0.65
HRH3_CAVPO HRH3 Histamine H3 receptor 2e-28 0.33
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 3.053e-28 0.39
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 6.187e-28 0.48
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.31e-27 0.45
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 9.245e-26 0.43
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.007e-25 0.60
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.765e-25 0.46
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 3.799e-25 0.30
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.615e-24 0.65
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 6.09e-24 0.44
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 8.809e-24 0.50
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.665e-23 0.50
G7PWB2_MACFA Melanocortin receptor 5 2.117e-23 0.29
DRD1_RAT Drd1 D(1A) dopamine receptor 6.298e-23 0.58
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 6.502e-23 0.36
H10_HUMAN H1-0 Histone H1.0 2.611e-22 0.43
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.907e-20 0.42
HRH2_HUMAN HRH2 Histamine H2 receptor 3.047e-20 0.43
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 4.773e-20 0.35
CASB_RAT Csn2 Beta-casein 7.845e-20 0.44
HRH3_RAT Hrh3 Histamine H3 receptor 4.705e-19 0.34
OPRX_HUMAN OPRL1 Nociceptin receptor 5.44e-19 0.36
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 2.903e-18 0.31
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 7.443e-18 0.36
HRH1_CAVPO HRH1 Histamine H1 receptor 2.22e-16 0.43
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 4.441e-16 0.34
5HT2A_CANLF HTR2A 5-hydroxytryptamine receptor 2A 7.772e-16 0.30
NK1R_CAVPO TACR1 Substance-P receptor 9.992e-16 0.39
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.332e-15 0.44
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.554e-15 0.47
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.665e-15 0.48
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.776e-15 0.42
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.109e-15 0.44
Q70GC6_9HEPC NS5B RNA-directed RNA polymerase 2.554e-15 0.32
MEN1_HUMAN MEN1 Menin 2.998e-15 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.441e-15 0.43
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.438e-15 0.44
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 1.121e-14 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 2.764e-14 0.43
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 4.363e-14 0.52
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 6.55e-14 0.34
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 8.815e-14 0.44
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.656e-13 0.44
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.794e-13 0.44
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.404e-13 0.44
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.012e-13 0.44
OPRD_HUMAN OPRD1 Delta-type opioid receptor 9.066e-13 0.43
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.405e-12 0.43
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.503e-12 0.38
Q63380_RAT NET Transporter 1.814e-12 0.43
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.397e-12 0.43
DRD5_HUMAN DRD5 D(1B) dopamine receptor 5.143e-12 0.43
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.181e-12 0.31
DRD3_CHLAE DRD3 D(3) dopamine receptor 7.362e-12 0.43
MURB_STAAU murB UDP-N-acetylenolpyruvoylglucosamine reductase 8.017e-12 0.29
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.321e-11 0.36
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 1.926e-11 0.44
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.351e-11 0.43
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 7.725e-11 0.32
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 9.081e-11 0.37
MURA_ECOLI murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 9.3e-11 0.29
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.124e-10 0.29
HRH3_HUMAN HRH3 Histamine H3 receptor 3.208e-10 0.35
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.213e-10 0.44
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.19e-10 0.48
HRH1_RAT Hrh1 Histamine H1 receptor 5.224e-10 0.48
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 7.808e-10 0.42
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 8.216e-10 0.39
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 8.765e-10 0.34
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 9.105e-10 0.44
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.165e-09 0.49
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.903e-09 0.30
PRGR_RABIT PGR Progesterone receptor 2.279e-09 0.30
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.58e-09 0.50
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 4.049e-09 0.34
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 4.298e-09 0.34
ACES_RAT Ache Acetylcholinesterase 7.139e-09 0.34
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 8.391e-09 0.36
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.368e-08 0.48
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.437e-08 0.34
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.689e-08 0.42
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.45e-08 0.43
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 4.6e-08 0.42
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 7.814e-08 0.40
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.04e-07 0.31
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.193e-07 0.44
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.471e-07 0.43
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.211e-07 0.46
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.535e-07 0.44
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 3.417e-07 0.44
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 4.819e-07 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 5.904e-07 0.28
ALK_HUMAN ALK ALK tyrosine kinase receptor 6.424e-07 0.42
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.454e-07 0.65
DRD3_RAT Drd3 D(3) dopamine receptor 7.634e-07 0.48
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 8.279e-07 0.31
EIS_MYCTU eis N-acetyltransferase Eis 1.055e-06 0.30
Q3Y5H1_9GAMC 3C-like protease 1.236e-06 0.29
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.438e-06 0.29
ACES_HUMAN ACHE Acetylcholinesterase 1.468e-06 0.40
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.7e-06 0.30
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 2.218e-06 0.43
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 2.377e-06 0.37
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 3.278e-06 0.30
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.349e-06 0.29
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 5.219e-06 0.44
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 5.379e-06 0.28
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 5.6e-06 0.33
MC5R_HUMAN MC5R Melanocortin receptor 5 7.277e-06 0.35
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 7.334e-06 0.33
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 9.207e-06 0.33

Etelcalcetide

FURIN_HUMAN FURIN Furin 3.522e-182 0.57
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 1.012e-158 0.57
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.716e-148 0.52
WDR5_HUMAN WDR5 WD repeat-containing protein 5 7.446e-141 0.67
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 2.188e-124 0.42
Q8I6Z5_PLAF7 Plasmepsin V 2.103e-121 0.53
MC4R_MOUSE Mc4r Melanocortin receptor 4 4.494e-114 0.50
MC5R_MOUSE Mc5r Melanocortin receptor 5 2.915e-111 0.50
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.255e-110 0.50
MC3R_MOUSE Mc3r Melanocortin receptor 3 7.332e-107 0.50
POLG_WNV Genome polyprotein 3.453e-102 0.42
ST14_MOUSE St14 Suppressor of tumorigenicity 14 protein homolog 4.503e-102 0.43
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 6.418e-102 0.47
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 7.817e-95 0.47
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 6.651e-94 0.45
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 7.849e-92 0.45
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 3.321e-83 0.47
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 2.808e-82 0.44
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 2.808e-82 0.44
CHIA_SERMA chiA Chitinase A 2.073e-77 0.45
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.917e-74 0.50
BXA1_CLOBH botA Botulinum neurotoxin type A 5.007e-74 0.46
KISSR_HUMAN KISS1R KiSS-1 receptor 1.877e-69 0.38
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 3.771e-69 0.44
CFAB_HUMAN CFB Complement factor B 1.439e-67 0.64
HEPS_HUMAN HPN Serine protease hepsin 1.116e-66 0.47
CBX7_HUMAN CBX7 Chromobox protein homolog 7 1.537e-59 0.39
TPP2_HUMAN TPP2 Tripeptidyl-peptidase 2 2.735e-54 0.43
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 2.344e-52 0.42
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 6.049e-51 0.47
GSTA2_HUMAN GSTA2 Glutathione S-transferase A2 2.707e-50 0.32
GSP_CRIFA GSP Glutathionylspermidine synthase 4.641e-50 0.35
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 9.777e-50 0.44
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 3.046e-49 0.49
CO2_HUMAN C2 Complement C2 3.639e-49 0.39
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.4e-47 0.50
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 1.465e-46 0.30
POLG_DEN26 Genome polyprotein 3.373e-45 0.44
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 9.177e-43 0.43
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 1.148e-42 0.37
OPRX_MOUSE Oprl1 Nociceptin receptor 4.252e-42 0.35
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 7.511e-42 0.40
Q91H74_9FLAV Genome polyprotein 1.128e-40 0.40
OTC_HUMAN OTC Ornithine carbamoyltransferase, mitochondrial 5.881e-40 0.32
MCA2_TRYBB MCA2 Metacaspase 5.906e-40 0.34
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 1.393e-39 0.32
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 8.6e-39 0.33
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.142e-38 0.39
Q95WR6_LEIDO Cysteine protease 1.507e-37 0.47
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 4.204e-36 0.42
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 6.352e-35 0.38
GRIA1_RAT Gria1 Glutamate receptor 1 6.399e-35 0.32
MC3R_HUMAN MC3R Melanocortin receptor 3 2.257e-34 0.39
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.638e-34 0.42
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 2.124e-31 0.50
OPRM_RAT Oprm1 Mu-type opioid receptor 8.941e-31 0.43
OPRD_RAT Oprd1 Delta-type opioid receptor 9.299e-31 0.42
CATZ_RAT Ctsz Cathepsin Z 6.531e-30 0.37
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.058e-29 0.32
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.096e-28 0.46
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.152e-28 0.43
IDE_HUMAN IDE Insulin-degrading enzyme 1.134e-27 0.34
ANPRC_HUMAN NPR3 Atrial natriuretic peptide receptor 3 1.995e-27 0.34
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.007e-27 0.42
MC4R_HUMAN MC4R Melanocortin receptor 4 4.906e-27 0.50
Q9NAW4_PLAFA Cysteine protease falcipain-3 7.155e-26 0.47
CHIB_SERMA chiB Chitinase B 1.657e-25 0.35
LGUL_HUMAN GLO1 Lactoylglutathione lyase 2.144e-24 0.31
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 3.333e-24 0.38
CD36_RAT Cd36 Platelet glycoprotein 4 4.425e-24 0.30
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 5.245e-24 0.30
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 2.221e-23 0.38
ELAS_PSEAE lasB Elastase 3.503e-23 0.51
CATJ_RAT Ctsj Cathepsin J 3.931e-23 0.37
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.398e-20 0.31
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 2.12e-20 0.46
NK1R_RAT Tacr1 Substance-P receptor 3.61e-20 0.37
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 7.989e-20 0.43
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 8.525e-20 0.36
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.115e-19 0.34
DPO1_THEAQ polA DNA polymerase I, thermostable 1.253e-19 0.33
CATC_RAT Ctsc Dipeptidyl peptidase 1 2.68e-19 0.37
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.163e-19 0.31
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.682e-19 0.30
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 6.65e-19 0.43
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 9.219e-19 0.35
PLMN_BOVIN PLG Plasminogen 1.057e-18 0.47
CCNA2_HUMAN CCNA2 Cyclin-A2 9.212e-18 0.43
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 9.308e-18 0.39
Q9ERC0_RAT Npy2r Neuropeptide Y receptor Y2 1.006e-17 0.28
NK3R_CAVPO TACR3 Neuromedin-K receptor 1.139e-17 0.35
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 1.11e-16 0.42
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 1.11e-15 0.32
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 1.11e-15 0.30
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.887e-15 0.30
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.665e-15 0.29
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 2.998e-15 0.36
NK2R_MESAU TACR2 Substance-K receptor 4.552e-15 0.35
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 4.774e-15 0.36
NTR1_RAT Ntsr1 Neurotensin receptor type 1 9.437e-15 0.30
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.987e-14 0.32
CATH_HUMAN CTSH Pro-cathepsin H 4.563e-14 0.47
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 7.605e-14 0.29
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 8.105e-14 0.36
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 1.693e-13 0.41
CATL1_HUMAN CTSL Cathepsin L1 1.931e-13 0.47
NEP_MOUSE Mme Neprilysin 2.482e-13 0.29
GLN1B_ECOLI glnA Glutamine synthetase 3.922e-13 0.29
NK1R_CAVPO TACR1 Substance-P receptor 6.223e-13 0.35
CATB_BOVIN CTSB Cathepsin B 1.495e-12 0.47
NOS1_MOUSE Nos1 Nitric oxide synthase, brain 1.77e-12 0.35
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 2.558e-12 0.36
NRP1_RAT Nrp1 Neuropilin-1 3.05e-12 0.30
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 3.653e-12 0.31
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 3.978e-12 0.43
Q9NBA7_PLAFA Cysteine protease falcipain-3 5.439e-12 0.32
CATB_RAT Ctsb Cathepsin B 6.678e-12 0.37
NRP1_HUMAN NRP1 Neuropilin-1 1.115e-11 0.31
FA11_HUMAN F11 Coagulation factor XI 2.349e-11 0.34
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 3.048e-11 0.32
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 3.597e-11 0.36
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 6.781e-11 0.39
LGUL_YEAST GLO1 Lactoylglutathione lyase 8.191e-11 0.29
NOS1_RAT Nos1 Nitric oxide synthase, brain 1.062e-10 0.37
ASH2L_HUMAN ASH2L Set1/Ash2 histone methyltransferase complex subunit ASH2 1.621e-10 0.28
RBBP5_HUMAN RBBP5 Retinoblastoma-binding protein 5 1.621e-10 0.28
NK2R_RAT Tacr2 Substance-K receptor 2.003e-10 0.35
CBX8_HUMAN CBX8 Chromobox protein homolog 8 3.215e-10 0.31
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 6.226e-10 0.34
ANPRA_HUMAN NPR1 Atrial natriuretic peptide receptor 1 1.1e-09 0.34
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 2.737e-09 0.37
R1AB_SARS rep Replicase polyprotein 1ab 5.734e-09 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 8.922e-09 0.40
PAPA1_CARPA Papain 1.016e-08 0.33
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 2.601e-08 0.42
OPRX_HUMAN OPRL1 Nociceptin receptor 3.027e-08 0.45
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 3.167e-08 0.32
O31048_PORGN DPP IV Dipeptidyl peptidase IV 3.736e-08 0.35
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 4.727e-08 0.45
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 5.111e-08 0.30
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 5.273e-08 0.35
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 5.387e-08 0.36
AMPB_RAT Rnpep Aminopeptidase B 7.232e-08 0.32
H9B8T9_CAPHI CTSB Cathepsin B 9.594e-08 0.47
NTR2_RAT Ntsr2 Neurotensin receptor type 2 9.863e-08 0.30
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.509e-07 0.33
CATD_HUMAN CTSD Cathepsin D 1.82e-07 0.38
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 1.848e-07 0.36
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 2.68e-07 0.28
ITB3_HUMAN ITGB3 Integrin beta-3 2.898e-07 0.52
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 3.493e-07 0.31
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 3.613e-07 0.52
GRIA3_HUMAN GRIA3 Glutamate receptor 3 5.631e-07 0.30
MEN1_HUMAN MEN1 Menin 7.002e-07 0.43
PROC_HUMAN PROC Vitamin K-dependent protein C 1.033e-06 0.35
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 1.687e-06 0.47
NK3R_RAT Tacr3 Neuromedin-K receptor 2.645e-06 0.32
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 3.273e-06 0.32
NK3R_HUMAN TACR3 Neuromedin-K receptor 3.433e-06 0.31
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 3.785e-06 0.36
FA7_HUMAN F7 Coagulation factor VII 3.883e-06 0.32
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 4.592e-06 0.33
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 5.06e-06 0.32
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 5.988e-06 0.30
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 6.543e-06 0.47
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 6.984e-06 0.43

Boscalid

G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 5.151e-177 0.61
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.408e-70 0.41
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.366e-70 0.38
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 1.376e-60 0.41
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.57e-50 0.34
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 2.433e-48 0.38
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.921e-48 0.34
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 1.548e-45 0.42
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.814e-43 0.41
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 2.679e-42 0.34
LUCI_AQULA Luciferin 4-monooxygenase 9.249e-42 0.42
IL1R1_HUMAN IL1R1 Interleukin-1 receptor type 1 5.881e-40 0.32
FA10_HUMAN F10 Coagulation factor X 1.52e-39 0.53
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 1.947e-38 0.30
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 4.115e-38 0.37
FABH_HAEIN fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.875e-36 0.29
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 8.333e-36 0.28
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.106e-35 0.37
PRIO_SHEEP PRNP Major prion protein 6.428e-35 0.31
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 2.432e-34 0.34
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 1.176e-29 0.49
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.817e-29 0.33
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 3.533e-26 0.33
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 9.834e-26 0.39
STXA_SHIDY stxA Shiga toxin subunit A 3.197e-25 0.37
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 5.509e-25 0.41
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 3.883e-22 0.33
WNT3A_MOUSE Wnt3a Protein Wnt-3a 4.595e-22 0.32
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 9.201e-22 0.41
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.912e-21 0.41
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.382e-20 0.33
PYGL_RAT Pygl Glycogen phosphorylase, liver form 2.402e-20 0.33
SMO_HUMAN SMO Smoothened homolog 7.242e-20 0.39
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 2.205e-19 0.33
STIM1_RAT Stim1 Stromal interaction molecule 1 3.461e-19 0.30
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 3.865e-19 0.30
RXFP2_HUMAN RXFP2 Relaxin receptor 2 1.039e-18 0.30
Q01HZ7_ORYSA OSIGBa0132E09-OSIGBa0108L24.11 Glutamine synthetase 1.126e-18 0.30
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.147e-18 0.44
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 4.057e-18 0.48
O31272_9GAMM imiS Beta-lactamase 5.323e-18 0.30
Q25615_ONCVO Chitinase 1.183e-17 0.35
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.223e-17 0.40
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.847e-17 0.34
STIM1_HUMAN STIM1 Stromal interaction molecule 1 3.655e-17 0.30
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 3.949e-17 0.30
MAP1_ECOLI map Methionine aminopeptidase 1.11e-16 0.40
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 1.11e-16 0.34
CNR1_HUMAN CNR1 Cannabinoid receptor 1 4.441e-16 0.44
MAP1_YEAST MAP1 Methionine aminopeptidase 1 7.772e-16 0.31
SHH_MOUSE Shh Sonic hedgehog protein 8.882e-16 0.38
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.332e-15 0.39
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 1.332e-15 0.30
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.443e-15 0.41
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 4.441e-15 0.29
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 8.882e-15 0.33
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 2.096e-13 0.35
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 4.234e-13 0.41
A3KMY8_BOVIN GUSB Beta-glucuronidase 5.428e-13 0.30
BXE_CLOBO botE Botulinum neurotoxin type E 6.352e-13 0.32
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.704e-12 0.34
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 2.984e-12 0.30
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 3.007e-12 0.32
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 6.882e-12 0.32
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 9.345e-12 0.33
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 9.664e-12 0.40
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 9.938e-12 0.38
CAN1_RAT Capn1 Calpain-1 catalytic subunit 1.021e-11 0.31
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 1.851e-11 0.41
H9CNL0_SPOEX Ryanodien receptor 3.122e-11 0.30
LUCI_PHOPY Luciferin 4-monooxygenase 4.849e-11 0.38
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 5.27e-11 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.347e-10 0.43
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.554e-10 0.38
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 2.142e-10 0.31
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 3.338e-10 0.32
S100B_HUMAN S100B Protein S100-B 8.972e-10 0.28
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 1.202e-09 0.33
LYAM1_HUMAN SELL L-selectin 1.445e-09 0.32
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.806e-09 0.33
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 2.858e-09 0.48
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.598e-09 0.29
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 4.305e-09 0.49
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 5.367e-09 0.30
SMO_MOUSE Smo Smoothened homolog 1.022e-08 0.42
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 1.322e-08 0.29
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.985e-08 0.31
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 2.018e-08 0.33
DPOL_HHV6U U38 DNA polymerase catalytic subunit 2.422e-08 0.29
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 4.633e-08 0.30
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 4.708e-08 0.31
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 4.866e-08 0.38
SORT_HUMAN SORT1 Sortilin 6.635e-08 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 7.316e-08 0.36
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 7.785e-08 0.44
HDAC2_HUMAN HDAC2 Histone deacetylase 2 8.029e-08 0.35
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 8.157e-08 0.30
SKN1_CAEEL skn-1 Protein skinhead-1 8.189e-08 0.30
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 9.002e-08 0.29
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1e-07 0.36
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.121e-07 0.40
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 1.465e-07 0.31
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.629e-07 0.33
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.843e-07 0.30
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 1.982e-07 0.30
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 2.023e-07 0.29
ITA4_HUMAN ITGA4 Integrin alpha-4 2.155e-07 0.35
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.419e-07 0.33
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.476e-07 0.39
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.806e-07 0.30
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 3.48e-07 0.33
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 3.96e-07 0.30
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 4.441e-07 0.38
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 4.479e-07 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 6.761e-07 0.33
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 7.241e-07 0.43
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 7.269e-07 0.30
SHH_HUMAN SHH Sonic hedgehog protein 7.538e-07 0.30
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 8.174e-07 0.40
GLR_HUMAN GCGR Glucagon receptor 8.251e-07 0.33
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 9.396e-07 0.29
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 9.396e-07 0.29
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 1.188e-06 0.38
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1.285e-06 0.30
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.368e-06 0.32
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 1.754e-06 0.37
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.91e-06 0.34
PTGES_HUMAN PTGES Prostaglandin E synthase 2.09e-06 0.38
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.562e-06 0.30
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.714e-06 0.37
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 2.86e-06 0.33
TLR7_HUMAN TLR7 Toll-like receptor 7 3.199e-06 0.38
EGLN1_HUMAN EGLN1 Egl nine homolog 1 3.864e-06 0.34
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 3.947e-06 0.42
APOB_HUMAN APOB Apolipoprotein B-100 4.084e-06 0.28
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 4.238e-06 0.37
MK14_RAT Mapk14 Mitogen-activated protein kinase 14 4.25e-06 0.29
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 4.377e-06 0.32
WDR5_HUMAN WDR5 WD repeat-containing protein 5 4.685e-06 0.34
Q8MWR1_SPOFR USP Ultraspiracle protein 5.189e-06 0.30
Q8MWR2_SPOFR EcR Ecdysteroid receptor 5.189e-06 0.30
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 6.947e-06 0.30
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 9.38e-06 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 9.983e-06 0.41

Lactitol

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 5.554e-132 0.49
LEG4_HUMAN LGALS4 Galectin-4 1.266e-63 0.38
LEG8_HUMAN LGALS8 Galectin-8 1.266e-63 0.38
B4EH87_BURCJ Lectin 3.06e-60 0.49
CXB2_HUMAN GJB2 Gap junction beta-2 protein 7.497e-47 0.37
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 1.023e-37 0.30
TYRO_HUMAN TYR Tyrosinase 2.156e-31 0.38
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 4.38e-29 0.28
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.095e-28 0.37
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 1.143e-28 0.30
Q77YF8_HV1H2 rev Protein Rev 1.914e-25 0.29
SUIS_RAT Si Sucrase-isomaltase, intestinal 2.287e-25 0.40
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 1.054e-23 0.33
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.745e-23 0.37
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 7.465e-23 0.29
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 3.759e-22 0.30
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 3.799e-22 0.35
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 1.103e-19 0.35
LYAG_RAT Gaa Lysosomal alpha-glucosidase 1.682e-19 0.40
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 1.039e-18 0.30
GDE_RABIT AGL Glycogen debranching enzyme 4.666e-18 0.40
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.11e-16 0.37
MAG_HUMAN MAG Myelin-associated glycoprotein 1.221e-15 0.31
LEG3_HUMAN LGALS3 Galectin-3 5.773e-15 0.38
ENV_HV1H2 env Envelope glycoprotein gp160 1.102e-13 0.30
CD69_HUMAN CD69 Early activation antigen CD69 7.838e-12 0.29
IL2_HUMAN IL2 Interleukin-2 1.797e-10 0.30
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.187e-10 0.37
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 1.045e-09 0.28
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 4.247e-09 0.34
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 4.864e-09 0.28
LEG9_HUMAN LGALS9 Galectin-9 3.86e-07 0.32
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 1.248e-06 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.425e-06 0.38
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.655e-06 0.35
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.962e-06 0.31

Gaxilose

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 3.684e-124 0.45
B4EH87_BURCJ Lectin 2.07e-71 0.45
LEG4_HUMAN LGALS4 Galectin-4 1.933e-57 0.33
LEG8_HUMAN LGALS8 Galectin-8 1.933e-57 0.33
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 1.532e-50 0.29
CXB2_HUMAN GJB2 Gap junction beta-2 protein 2.89e-41 0.33
FAS_CHICK FASN Fatty acid synthase 7.101e-36 0.28
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 1.377e-35 0.28
TYRO_HUMAN TYR Tyrosinase 1.073e-28 0.36
FGF1_HUMAN FGF1 Fibroblast growth factor 1 5.702e-26 0.32
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 1.144e-22 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.672e-21 0.32
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 3.436e-19 0.30
MRAY_ECOLI mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 8.29e-19 0.30
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 1.523e-18 0.29
GDE_RABIT AGL Glycogen debranching enzyme 1.11e-16 0.38
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.11e-16 0.30
ENV_HV1H2 env Envelope glycoprotein gp160 1.332e-15 0.34
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 2.554e-15 0.32
IL2_HUMAN IL2 Interleukin-2 3.886e-15 0.29
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 6.994e-15 0.30
LEG3_HUMAN LGALS3 Galectin-3 3.054e-11 0.33
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 1.471e-10 0.31
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 6.439e-10 0.29
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 2.429e-09 0.31
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 3.108e-09 0.29
O96394_LEIAM Arginase 5.897e-09 0.30
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 1.163e-08 0.30
MAG_HUMAN MAG Myelin-associated glycoprotein 5.293e-08 0.30
CDD_MOUSE Cda Cytidine deaminase 4.268e-07 0.29
CAH12_HUMAN CA12 Carbonic anhydrase 12 7.263e-07 0.37
PDIA1_HUMAN P4HB Protein disulfide-isomerase 7.411e-07 0.31
CAH13_HUMAN CA13 Carbonic anhydrase 13 1.416e-06 0.32
LEG9_HUMAN LGALS9 Galectin-9 1.858e-06 0.28
PPO2_AGABI PPO2 Polyphenol oxidase 2 4.758e-06 0.36
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 5.289e-06 0.33
CAH9_HUMAN CA9 Carbonic anhydrase 9 7.161e-06 0.37

Calcium_glubionate_anhydrous

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 3.439e-102 0.38
LEG4_HUMAN LGALS4 Galectin-4 1.061e-54 0.31
LEG8_HUMAN LGALS8 Galectin-8 1.061e-54 0.31
B4EH87_BURCJ Lectin 1.442e-47 0.36
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 6.305e-46 0.30
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 1.853e-44 0.29
CXB2_HUMAN GJB2 Gap junction beta-2 protein 4.694e-40 0.32
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 7.545e-40 0.32
FGF1_HUMAN FGF1 Fibroblast growth factor 1 2.401e-26 0.34
MAG_HUMAN MAG Myelin-associated glycoprotein 1.989e-23 0.32
TYRO_HUMAN TYR Tyrosinase 5.228e-22 0.33
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.833e-21 0.34
MRAY_ECOLI mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.698e-18 0.29
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 2.898e-18 0.29
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 2.22e-16 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.554e-15 0.34
GDE_RABIT AGL Glycogen debranching enzyme 3.408e-14 0.31
ENV_HV1H2 env Envelope glycoprotein gp160 1.081e-13 0.30
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.765e-12 0.31
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 4.286e-12 0.32
CD69_HUMAN CD69 Early activation antigen CD69 6.736e-12 0.29
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.014e-11 0.32
LEG3_HUMAN LGALS3 Galectin-3 4.044e-11 0.32
IL2_HUMAN IL2 Interleukin-2 1.602e-10 0.30
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 4.884e-10 0.29
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 8.682e-10 0.28
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 4.099e-09 0.28
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 1.635e-08 0.29
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 7.387e-08 0.29
LEG9_HUMAN LGALS9 Galectin-9 4.312e-07 0.32
BGAL_HUMAN GLB1 Beta-galactosidase 7.518e-07 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 7.6e-06 0.32

Methylprednisone

ATTY_RAT Tat Tyrosine aminotransferase 2.65e-82 0.32
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.639e-57 0.56
Q690N0_BOVIN PGR Progesterone receptor 2.172e-42 0.44
GCR_MOUSE Nr3c1 Glucocorticoid receptor 2.741e-25 0.52
GCR_HUMAN NR3C1 Glucocorticoid receptor 5.487e-25 0.70
SHBG_HUMAN SHBG Sex hormone-binding globulin 8.744e-21 0.52
CP19A_HUMAN CYP19A1 Aromatase 1.11e-16 0.47
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.661e-16 0.52
GLNA_HUMAN GLUL Glutamine synthetase 6.661e-16 0.52
IL6_HUMAN IL6 Interleukin-6 1.199e-12 0.52
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 5.842e-11 0.39
PRGR_RABIT PGR Progesterone receptor 5.312e-09 0.28
GCR_RAT Nr3c1 Glucocorticoid receptor 1.554e-08 0.52

Nicoboxil

THAS_HUMAN TBXAS1 Thromboxane-A synthase 9.783e-74 0.44
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 1.181e-67 0.38
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 6.262e-65 0.34
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.805e-55 0.37
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 1.573e-39 0.32
ERG1_RAT Sqle Squalene monooxygenase 1.607e-39 0.38
TLR1_HUMAN TLR1 Toll-like receptor 1 3.875e-36 0.29
MIP_LEGPN mip Outer membrane protein MIP 1.212e-34 0.44
GYRB_STRPN gyrB DNA gyrase subunit B 8.085e-33 0.32
Q7X1P7_STREE parE DNA topoisomerase (ATP-hydrolyzing) 8.085e-33 0.32
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.674e-30 0.38
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.04e-28 0.36
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 3.174e-28 0.47
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.374e-26 0.32
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.374e-26 0.32
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 6.377e-23 0.28
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 8.842e-19 0.34
KLK14_HUMAN KLK14 Kallikrein-14 3.488e-18 0.29
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 4.617e-17 0.44
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 1.11e-16 0.42
GRP3_HUMAN RASGRP3 Ras guanyl-releasing protein 3 1.11e-16 0.32
ISPH_AQUAE ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1.11e-16 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.11e-16 0.39
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.11e-16 0.36
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 1.554e-15 0.31
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.776e-15 0.35
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 7.661e-15 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 8.438e-15 0.45
FA12_HUMAN F12 Coagulation factor XII 2.287e-14 0.32
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.642e-14 0.43
EST1_RABIT Liver carboxylesterase 1 2.347e-13 0.33
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.859e-13 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 3.213e-13 0.41
POLG_HCV77 Genome polyprotein 4.426e-13 0.39
CYSP_PLAFA Trophozoite cysteine proteinase 7.956e-13 0.38
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 1.589e-12 0.34
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.669e-12 0.31
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.924e-12 0.33
HRH3_RAT Hrh3 Histamine H3 receptor 9.011e-12 0.41
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 1.387e-11 0.38
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 4.086e-11 0.35
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 6.132e-11 0.29
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.213e-10 0.29
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 2.381e-10 0.34
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 2.46e-10 0.35
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 3.836e-10 0.34
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 6.127e-10 0.34
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 8.149e-10 0.31
Q4Q5W4_LEIMA Putative squalene synthase 1.087e-09 0.28
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 1.281e-09 0.34
ACHP_LYMST Acetylcholine-binding protein 1.334e-09 0.33
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 1.523e-09 0.30
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.698e-09 0.34
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 2.492e-09 0.34
PLM2_PLAFA Plasmepsin-2 3.551e-09 0.37
DOPO_RAT Dbh Dopamine beta-hydroxylase 5.367e-09 0.30
TA2R_RAT Tbxa2r Thromboxane A2 receptor 7.165e-09 0.36
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 7.167e-09 0.33
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.026e-08 0.38
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 2.148e-08 0.31
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 2.397e-08 0.38
NSMA_RAT Smpd2 Sphingomyelin phosphodiesterase 2 3.935e-08 0.32
STS_HUMAN STS Steryl-sulfatase 4.719e-08 0.40
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 5.315e-08 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.031e-07 0.29
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.507e-07 0.33
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.661e-07 0.30
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.866e-07 0.31
RARA_HUMAN RARA Retinoic acid receptor alpha 2.009e-07 0.41
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 2.362e-07 0.29
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 2.416e-07 0.29
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.801e-07 0.30
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 3.167e-07 0.30
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.54e-07 0.34
GATA4_MOUSE Gata4 Transcription factor GATA-4 6.322e-07 0.28
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 6.322e-07 0.28
ACRO_HUMAN ACR Acrosin 6.486e-07 0.32
EST2_HUMAN CES2 Cocaine esterase 8.75e-07 0.33
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 9.069e-07 0.33
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 9.354e-07 0.37
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.136e-06 0.40
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.429e-06 0.31
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 1.683e-06 0.29
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 1.696e-06 0.40
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.961e-06 0.34
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.202e-06 0.64
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 2.488e-06 0.30
KLK5_HUMAN KLK5 Kallikrein-5 2.558e-06 0.29
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 2.685e-06 0.31
Q9FYV8_MAIZE Protoporphyrinogen oxidase 2.819e-06 0.31
NR1H4_MOUSE Nr1h4 Bile acid receptor 2.917e-06 0.30
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.964e-06 0.39
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 3.052e-06 0.38
SMO_MOUSE Smo Smoothened homolog 3.124e-06 0.33
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 3.133e-06 0.28
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 3.292e-06 0.33
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.683e-06 0.46
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.045e-06 0.33
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.479e-06 0.33
H6TY12_PERAM Nicotinic acetylcholine receptor alpha8 subunit 5.567e-06 0.28
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 7.112e-06 0.29
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 7.615e-06 0.38

Biguanide

DHYS_RAT Dhps Deoxyhypusine synthase 1.331e-67 0.39
Q9GSW0_PLAFA dhs Deoxyhypusine synthase 3.824e-40 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.914e-12 0.29
PAO1_MAIZE MPAO1 Polyamine oxidase 1 1.265e-11 0.33
S100B_HUMAN S100B Protein S100-B 2.659e-10 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.763e-08 0.29
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 7.011e-08 0.54

Isoxaflutole

SC6A9_BOVIN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 4.572e-63 0.37
HPPD_DAUCA 4-hydroxyphenylpyruvate dioxygenase 1.61e-60 0.48
CCR7_HUMAN CCR7 C-C chemokine receptor type 7 3.17e-38 0.30
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 2.157e-25 0.44
H9YX08_MACMU CCR6 C-C chemokine receptor type 6 1.342e-24 0.30
CRFR1_HUMAN CRHR1 Corticotropin-releasing factor receptor 1 4.41e-18 0.36
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.221e-15 0.44
SORT_HUMAN SORT1 Sortilin 9.581e-14 0.31
CCRL2_HUMAN CCRL2 C-C chemokine receptor-like 2 1.091e-13 0.30
HPPD_RAT Hpd 4-hydroxyphenylpyruvate dioxygenase 1.296e-13 0.30
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.974e-11 0.30
H9CNL0_SPOEX Ryanodien receptor 8.191e-11 0.29
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 1.804e-09 0.33
CRFR2_HUMAN CRHR2 Corticotropin-releasing factor receptor 2 2.603e-09 0.29
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 3.242e-09 0.35
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 3.598e-09 0.29
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 2.379e-08 0.29
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 3.944e-08 0.30
ELNE_HUMAN ELANE Neutrophil elastase 3.463e-06 0.31
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.112e-06 0.29
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 7.667e-06 0.37
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 9.373e-06 0.31

Lusutrombopag

TPOR_HUMAN MPL Thrombopoietin receptor 1.398e-59 0.40
PPAF_PHAVU Fe(3+)-Zn(2+) purple acid phosphatase 2.599e-48 0.31
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 5.644e-40 0.34
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 3.055e-23 0.34
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 3.062e-22 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 4.441e-16 0.31
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 9.77e-15 0.29
KCNQ1_HUMAN KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 5.287e-12 0.30
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 4.989e-11 0.34
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.675e-10 0.28
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 2.358e-09 0.32
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 6.236e-09 0.32
HXK4_HUMAN GCK Hexokinase-4 1.276e-08 0.33
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 2.521e-07 0.30
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 3.384e-07 0.31
PTGES_HUMAN PTGES Prostaglandin E synthase 1.458e-06 0.40
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.934e-06 0.31

Ozenoxacin

Q47245_ECOLX gyrA DNA gyrase subunit A 1.792e-50 0.35
C3SLN2_ECOLX gyrB DNA gyrase subunit B 1.003e-43 0.35
ACEA_MYCTU icl Isocitrate lyase 7.655e-34 0.35
DPO3_BACSU polC DNA polymerase III PolC-type 2.747e-21 0.35
GLYCP_NIPAV G Glycoprotein G 7.772e-16 0.30
CNR2_RAT Cnr2 Cannabinoid receptor 2 1.221e-15 0.33
PARC_STAAU parC DNA topoisomerase 4 subunit A 1.892e-12 0.38
P2Y12_RAT P2ry12 P2Y purinoceptor 12 2.677e-09 0.29
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 6.444e-09 0.32
GYRA_MYCTU gyrA DNA gyrase subunit A 2.774e-07 0.38
GYRA_STAAU gyrA DNA gyrase subunit A 7.685e-07 0.37
ATAD2_HUMAN ATAD2 ATPase family AAA domain-containing protein 2 1.66e-06 0.29
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 3.575e-06 0.32

Secnidazole

A3KMY8_BOVIN GUSB Beta-glucuronidase 1.543e-41 0.47
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.242e-32 0.49
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.32e-29 0.32
C4LW95_ENTHI Thioredoxin reductase 2.072e-10 0.42
TYSY_HUMAN TYMS Thymidylate synthase 2.43e-10 0.45
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.591e-08 0.47
EGFR_HUMAN EGFR Epidermal growth factor receptor 7.131e-07 0.47
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 5.652e-06 0.49

Oteseconazole

Q96W81_ASPFM cyp51B 14-alpha sterol demethylase 1.579e-33 0.34
CP121_MYCTU cyp121 Mycocyclosin synthase 8.697e-28 0.34
CP51A_ASPFU cyp51A 14-alpha sterol demethylase Cyp51A 1.193e-19 0.31
CP51_CANAL ERG11 Lanosterol 14-alpha demethylase 1.193e-19 0.31
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 7.356e-11 0.34

Amitriptylinoxide

GAG_AVIER gag Gag polyprotein 6.605e-27 0.31
ENV_MMTVG env Envelope glycoprotein gp70 5.776e-24 0.31
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 1.11e-16 0.42
HRH1_CAVPO HRH1 Histamine H1 receptor 5.218e-15 0.37
HRH1_RAT Hrh1 Histamine H1 receptor 4.237e-11 0.58
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 2.724e-09 0.32
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.482e-06 0.29
STE24_YEAST STE24 CAAX prenyl protease 1 2.482e-06 0.37

Lumefantrine_co-artemether

Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 7.576e-26 0.43

Darolutamide

ANDR_HUMAN AR Androgen receptor 3.124e-10 0.38
FA11_HUMAN F11 Coagulation factor XI 1.175e-09 0.34
P2RX3_RAT P2rx3 P2X purinoceptor 3 1.105e-07 0.31
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.602e-07 0.34
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 2.611e-06 0.29
ANDR_RAT Ar Androgen receptor 3.37e-06 0.30
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 8.461e-06 0.30

Dihydralazine

I23O1_MOUSE Ido1 Indoleamine 2,3-dioxygenase 1 4.413e-09 0.39