Results of Job: search_4a51022b-6c6d-4c94-949e-e71e12b8416c

Query Target Key Target Name Description P-Value MaxTC

compound_1

EGFR_HUMAN EGFR Epidermal growth factor receptor 0 0.75
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 8.209e-285 0.56
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.094e-226 0.56
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.566e-218 0.57
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.986e-158 0.74
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.359e-145 0.57
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.337e-122 0.57
C3SLB7_ECOLX glmU Bifunctional protein GlmU 9.021e-105 0.75
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 7.813e-96 0.62
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 5.907e-85 0.55
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 5.906e-76 0.34
AURKA_HUMAN AURKA Aurora kinase A 6.609e-75 0.85
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 8.124e-75 0.73
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 4.937e-74 0.55
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 3.938e-73 0.55
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 1.571e-72 0.62
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.85e-67 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.183e-63 0.63
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 6.972e-61 0.35
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.426e-59 0.39
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 3.784e-58 0.43
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.606e-57 0.61
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 3.922e-57 0.46
EGFR_MOUSE Egfr Epidermal growth factor receptor 7.414e-55 0.37
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 3.753e-53 0.47
AURKB_HUMAN AURKB Aurora kinase B 7.582e-53 0.85
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 3.775e-52 0.47
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 1.377e-51 0.30
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.643e-48 0.57
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 1.518e-47 0.35
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 3.415e-47 0.38
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 5.868e-47 0.35
ATM_HUMAN ATM Serine-protein kinase ATM 8.254e-47 0.40
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.358e-46 0.55
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 9.755e-46 0.43
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.788e-44 0.40
TIE2_HUMAN TEK Angiopoietin-1 receptor 5.784e-41 0.55
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 8.049e-41 0.58
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.909e-38 0.47
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.146e-37 0.61
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 2.845e-37 0.47
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.651e-36 0.59
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 1.839e-36 0.36
MET_HUMAN MET Hepatocyte growth factor receptor 3.001e-36 0.61
PACR_RAT Adcyap1r1 Pituitary adenylate cyclase-activating polypeptide type I receptor 1.097e-35 0.28
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.912e-35 0.49
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 3.293e-34 0.47
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 7.414e-34 0.37
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.859e-33 0.42
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.239e-32 0.35
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 3.406e-31 0.47
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 7.774e-31 0.60
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 3.255e-30 0.68
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7.203e-30 0.54
CCNT1_HUMAN CCNT1 Cyclin-T1 9.297e-30 0.54
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.19e-29 0.38
SHH_MOUSE Shh Sonic hedgehog protein 3.648e-29 0.39
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 6.135e-29 0.37
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.766e-28 0.47
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.133e-27 0.47
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 5.902e-27 0.47
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.091e-26 0.37
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.562e-26 0.47
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 2.383e-26 0.44
LCK_HUMAN LCK Tyrosine-protein kinase Lck 8.728e-26 0.73
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1.037e-25 0.43
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.917e-25 0.37
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 1.685e-24 0.30
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.877e-24 0.51
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 5.882e-24 0.47
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 7.015e-24 0.39
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.635e-23 0.55
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.441e-23 0.61
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 5.618e-23 0.34
LUCI_RENRE Coelenterazine h 2-monooxygenase 1.707e-22 0.53
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1.709e-22 0.68
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.15e-22 0.32
LUCI_AQULA Luciferin 4-monooxygenase 2.262e-22 0.33
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 7.046e-22 0.41
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.04e-21 0.32
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.074e-21 0.31
LUCI_PHOPY Luciferin 4-monooxygenase 1.904e-21 0.39
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.974e-21 0.34
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 5.194e-21 0.47
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 5.926e-21 0.63
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.066e-20 0.33
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.466e-20 0.47
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.833e-20 0.54
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 1.924e-20 0.28
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 2.755e-20 0.32
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 5.666e-20 0.47
CTRO_HUMAN CIT Citron Rho-interacting kinase 6.327e-20 0.47
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 7.443e-20 0.47
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 8.357e-20 0.32
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 9.376e-20 0.33
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 9.982e-20 0.34
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 1.053e-19 0.33
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.161e-19 0.49
CCRL2_HUMAN CCRL2 C-C chemokine receptor-like 2 1.386e-19 0.32
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 2.411e-19 0.59
GAK_HUMAN GAK Cyclin-G-associated kinase 2.45e-19 0.47
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 4.539e-19 0.47
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 4.649e-19 0.47
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 7.003e-19 0.47
PRIO_SHEEP PRNP Major prion protein 7.02e-19 0.32
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 9.436e-19 0.61
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 9.601e-19 0.39
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 1.344e-18 0.47
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.347e-18 0.47
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1.372e-18 0.29
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 2.21e-18 0.61
PANC_MYCTU panC Pantothenate synthetase 3.399e-18 0.32
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 3.72e-18 0.29
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 3.732e-18 0.33
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 3.741e-18 0.47
UHRF1_HUMAN UHRF1 E3 ubiquitin-protein ligase UHRF1 4.879e-18 0.29
TOP2_PLAFK TOP2 DNA topoisomerase 2 6.785e-18 0.28
KLF5_HUMAN KLF5 Krueppel-like factor 5 7.752e-18 0.34
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 8.151e-18 0.31
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 1.064e-17 0.35
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 1.2e-17 0.55
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.338e-17 0.47
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.466e-17 0.42
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.386e-17 0.47
STRP_STRP1 ska Streptokinase A 3.518e-17 0.39
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 3.75e-17 0.62
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 4.081e-17 0.35
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 4.441e-17 0.75
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 5.345e-17 0.54
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.11e-16 0.55
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.11e-16 0.47
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 2.22e-16 0.47
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.22e-16 0.47
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.22e-16 0.47
INSR_HUMAN INSR Insulin receptor 3.331e-16 0.59
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.331e-16 0.47
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 3.331e-16 0.47
SMO_HUMAN SMO Smoothened homolog 3.331e-16 0.39
AHK3_ARATH AHK3 Histidine kinase 3 4.441e-16 0.31
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 4.441e-16 0.38
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 5.551e-16 0.41
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 7.772e-16 0.60
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.772e-16 0.57
HDAC6_HUMAN HDAC6 Histone deacetylase 6 7.772e-16 0.55
HXK4_HUMAN GCK Hexokinase-4 1.332e-15 0.36
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.665e-15 0.47
RON_HUMAN MST1R Macrophage-stimulating protein receptor 1.887e-15 0.36
HD_HUMAN HTT Huntingtin 1.998e-15 0.35
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.331e-15 0.47
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.776e-15 0.55
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.887e-15 0.40
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.664e-15 0.52
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 3.886e-15 0.41
FTSZ_STAAU ftsZ Cell division protein FtsZ 4.441e-15 0.29
PRIO_HUMAN PRNP Major prion protein 4.774e-15 0.36
HPSE_HUMAN HPSE Heparanase 5.995e-15 0.36
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 6.439e-15 0.47
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 8.438e-15 0.47
ANDR_MOUSE Ar Androgen receptor 8.882e-15 0.32
AURKA_MOUSE Aurka Aurora kinase A 1.743e-14 0.32
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.776e-14 0.47
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 2.442e-14 0.47
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 2.598e-14 0.47
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.841e-14 0.39
PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 7.538e-14 0.36
DMPK_HUMAN DMPK Myotonin-protein kinase 7.594e-14 0.47
CASB_RAT Csn2 Beta-casein 8.293e-14 0.30
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 9.504e-14 0.30
CYSP_PLAFA Trophozoite cysteine proteinase 1.003e-13 0.30
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.091e-13 0.43
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.407e-13 0.47
FAK1_HUMAN PTK2 Focal adhesion kinase 1 1.544e-13 0.47
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.648e-13 0.57
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 1.648e-13 0.47
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.907e-13 0.36
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 2.142e-13 0.36
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 2.511e-13 0.47
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.571e-13 0.35
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 2.641e-13 0.37
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 2.675e-13 0.42
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 3.795e-13 0.41
HDAC3_HUMAN HDAC3 Histone deacetylase 3 3.851e-13 0.46
ACES_TETCF ache Acetylcholinesterase 4.974e-13 0.38
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 5.095e-13 0.47
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 5.641e-13 0.28
Q9HUN3_PSEAE dnaB Replicative DNA helicase 6.449e-13 0.28
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 8.809e-13 0.32
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 9.822e-13 0.32
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 1.311e-12 0.48
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 1.551e-12 0.47
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 2.037e-12 0.36
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2.179e-12 0.30
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 2.491e-12 0.47
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.492e-12 0.33
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.546e-12 0.47
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 2.669e-12 0.38
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.086e-12 0.30
Q25270_LEIDO beta-tubulin Beta-tubulin 3.233e-12 0.31
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 4.336e-12 0.31
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 5.451e-12 0.36
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 7.501e-12 0.48
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.277e-11 0.41
TPOR_HUMAN MPL Thrombopoietin receptor 1.327e-11 0.34
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.374e-11 0.33
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.792e-11 0.33
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 2.086e-11 0.40
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.24e-11 0.61
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.454e-11 0.36
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 2.783e-11 0.30
POLG_CXB3N Genome polyprotein 2.85e-11 0.32
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 2.99e-11 0.35
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 3.852e-11 0.34
VP16_HHV11 Tegument protein VP16 4.634e-11 0.48
MINK1_HUMAN MINK1 Misshapen-like kinase 1 7.119e-11 0.47
MITF_HUMAN MITF Microphthalmia-associated transcription factor 8.332e-11 0.35
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 8.451e-11 0.47
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 8.593e-11 0.34
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1.073e-10 0.61
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.228e-10 0.41
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 1.245e-10 0.43
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 1.245e-10 0.28
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 1.47e-10 0.36
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.86e-10 0.55
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 2.143e-10 0.29
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 2.281e-10 0.47
EST1_RABIT Liver carboxylesterase 1 2.341e-10 0.34
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.659e-10 0.30
FRK_HUMAN FRK Tyrosine-protein kinase FRK 2.933e-10 0.47
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 3.585e-10 0.31
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 3.674e-10 0.41
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 3.8e-10 0.36
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 4.216e-10 0.38
AURKC_HUMAN AURKC Aurora kinase C 4.734e-10 0.47
Q76129_9HIV1 gag Structural capsid protein 5.139e-10 0.35
DYR_ENTFC folA Dihydrofolate reductase 6.4e-10 0.30
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 6.641e-10 0.30
GLR_RAT Gcgr Glucagon receptor 7.563e-10 0.39
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 8.401e-10 0.35
KS6A2_MOUSE Rps6ka2 Ribosomal protein S6 kinase alpha-2 8.811e-10 0.28
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 9.27e-10 0.43
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 9.852e-10 0.28
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 1.025e-09 0.36
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 1.149e-09 0.42
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 1.21e-09 0.32
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1.623e-09 0.47
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.781e-09 0.39
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.836e-09 0.41
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.907e-09 0.33
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 2.283e-09 0.41
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 2.413e-09 0.31
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.469e-09 0.41
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.762e-09 0.36
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.94e-09 0.31
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.026e-09 0.42
GLR_HUMAN GCGR Glucagon receptor 3.092e-09 0.39
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 3.212e-09 0.63
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.254e-09 0.34
Q49PX0_9POXV N1L N1L 3.394e-09 0.33
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 3.398e-09 0.29
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 3.489e-09 0.47
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 3.522e-09 0.36
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 3.522e-09 0.36
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 3.524e-09 0.31
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 3.887e-09 0.41
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 3.897e-09 0.41
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 4.087e-09 0.30
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 4.25e-09 0.47
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 4.382e-09 0.70
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 4.652e-09 0.47
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.978e-09 0.32
CCNA2_HUMAN CCNA2 Cyclin-A2 5.018e-09 0.54
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 5.634e-09 0.34
ACES_HUMAN ACHE Acetylcholinesterase 5.928e-09 0.38
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 5.95e-09 0.47
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 6.199e-09 0.43
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 6.236e-09 0.54
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 7.911e-09 0.39
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 7.97e-09 0.36
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 7.983e-09 0.36
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 8.035e-09 0.36
CDN1A_HUMAN CDKN1A Cyclin-dependent kinase inhibitor 1 8.719e-09 0.29
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 8.719e-09 0.29
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 8.923e-09 0.36
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 9.059e-09 0.54
UREA_CANEN Urease 1.056e-08 0.32
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 1.088e-08 0.34
IL6_HUMAN IL6 Interleukin-6 1.109e-08 0.34
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 1.314e-08 0.28
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 1.453e-08 0.28
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 1.641e-08 0.36
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 1.787e-08 0.59
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.812e-08 0.34
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 2.033e-08 0.41
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 2.04e-08 0.36
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 2.194e-08 0.31
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 2.209e-08 0.47
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.672e-08 0.30
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 2.982e-08 0.34
Q53I59_TRYCR PDEC Phosphodiesterase 3.485e-08 0.29
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 3.717e-08 0.30
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 3.758e-08 0.34
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 4e-08 0.34
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 4.438e-08 0.36
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 4.559e-08 0.36
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 4.589e-08 0.28
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 5.153e-08 0.61
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 5.3e-08 0.35
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 7.244e-08 0.38
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 7.519e-08 0.32
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 7.911e-08 0.38
ACVR1_HUMAN ACVR1 Activin receptor type-1 8.113e-08 0.43
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 8.266e-08 0.34
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 8.651e-08 0.47
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 9.594e-08 0.47
CHLE_HUMAN BCHE Cholinesterase 9.911e-08 0.38
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1.015e-07 0.41
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.121e-07 0.28
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.17e-07 0.37
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1.233e-07 0.47
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.324e-07 0.28
SYK_HUMAN KARS1 Lysine--tRNA ligase 1.444e-07 0.37
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 1.458e-07 0.47
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 1.483e-07 0.32
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 1.889e-07 0.38
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.915e-07 0.35
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.923e-07 0.55
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 2.044e-07 0.47
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.052e-07 0.35
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 2.198e-07 0.34
YES_HUMAN YES1 Tyrosine-protein kinase Yes 2.232e-07 0.47
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.272e-07 0.41
ACES_ELEEL ache Acetylcholinesterase 2.307e-07 0.38
HCK_HUMAN HCK Tyrosine-protein kinase HCK 2.524e-07 0.47
MEX5_CAEEL mex-5 Zinc finger protein mex-5 2.67e-07 0.33
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 2.788e-07 0.30
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 3.03e-07 0.34
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 3.075e-07 0.47
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 3.129e-07 0.47
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 3.545e-07 0.47
FA7_HUMAN F7 Coagulation factor VII 3.566e-07 0.36
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 3.598e-07 0.33
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 3.851e-07 0.41
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 3.976e-07 0.36
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 4.079e-07 0.34
ACRO_HUMAN ACR Acrosin 4.181e-07 0.32
KLK5_HUMAN KLK5 Kallikrein-5 4.3e-07 0.33
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 4.707e-07 0.30
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 5.438e-07 0.61
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 5.643e-07 0.34
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 6.137e-07 0.30
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 6.148e-07 0.28
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 6.596e-07 0.40
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 7.3e-07 0.47
HSF1_MOUSE Hsf1 Heat shock factor protein 1 7.337e-07 0.40
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 7.559e-07 0.33
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 7.684e-07 0.34
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 7.975e-07 0.36
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 8.44e-07 0.47
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 9.056e-07 0.32
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 9.585e-07 0.36
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 9.642e-07 0.34
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.011e-06 0.28
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.199e-06 0.36
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.21e-06 0.41
O61059_LEIME LmGT2 Glucose transporter 1.254e-06 0.43
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.506e-06 0.31
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 1.583e-06 0.34
DYR_BOVIN DHFR Dihydrofolate reductase 1.603e-06 0.32
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.686e-06 0.41
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 1.887e-06 0.34
GLI1_MOUSE Gli1 Zinc finger protein GLI1 1.892e-06 0.32
LMP1_EBVB9 LMP1 Latent membrane protein 1 1.938e-06 0.32
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.026e-06 0.34
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 2.094e-06 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.369e-06 0.29
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 2.444e-06 0.31
KLK7_HUMAN KLK7 Kallikrein-7 2.632e-06 0.33
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 2.991e-06 0.43
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 3.047e-06 0.28
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 3.083e-06 0.36
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 3.107e-06 0.36
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 3.273e-06 0.32
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.462e-06 0.34
SENP1_HUMAN SENP1 Sentrin-specific protease 1 3.477e-06 0.28
USP_DROME usp Protein ultraspiracle 3.596e-06 0.33
Q7T1G6_DANRE trpn1 Ion channel NompC 3.703e-06 0.36
SCAF_HCMVA UL80 Capsid scaffolding protein 3.783e-06 0.31
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 3.811e-06 0.47
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.878e-06 0.35
GRM1_RAT Grm1 Metabotropic glutamate receptor 1 3.879e-06 0.36
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 4.421e-06 0.29
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 4.433e-06 0.36
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 4.521e-06 0.37
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 4.902e-06 0.28
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.03e-06 0.30
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 5.123e-06 0.32
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 5.555e-06 0.35
RXFP1_HUMAN RXFP1 Relaxin receptor 1 5.565e-06 0.30
CATL2_HUMAN CTSV Cathepsin L2 5.749e-06 0.37
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 5.845e-06 0.36
O97467_PLAFA ht1 Hexose transporter 1 5.924e-06 0.43
NK3R_HUMAN TACR3 Neuromedin-K receptor 5.957e-06 0.33
NR1H4_HUMAN NR1H4 Bile acid receptor 6.209e-06 0.38
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 6.797e-06 0.61
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 7.098e-06 0.42
INSRR_HUMAN INSRR Insulin receptor-related protein 7.57e-06 0.28
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 7.968e-06 0.47
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 8.041e-06 0.32
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 8.25e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 8.558e-06 0.28
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 9.115e-06 0.34