Results of Job: search_4ab1f65b-2ce4-47d9-97c5-0e8c6c4102fd

Query Target Key Target Name Description P-Value MaxTC

compound_1

KPYR_HUMAN PKLR Pyruvate kinase PKLR 2.607e-140 0.39
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.788e-131 0.53
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 2.164e-127 0.44
LIMK2_HUMAN LIMK2 LIM domain kinase 2 3.172e-103 0.38
CCRL2_HUMAN CCRL2 C-C chemokine receptor-like 2 8.915e-76 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.495e-68 0.44
GYRB_MYCS2 gyrB DNA gyrase subunit B 3.895e-68 0.36
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 6.295e-63 0.52
AKTS1_HUMAN AKT1S1 Proline-rich AKT1 substrate 1 1.787e-62 0.41
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 4.638e-59 0.58
PRIO_SHEEP PRNP Major prion protein 5.9e-55 0.35
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 8.161e-51 0.39
TERT_HUMAN TERT Telomerase reverse transcriptase 7.632e-46 0.39
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.227e-44 0.34
GTR3_HUMAN SLC2A3 Solute carrier family 2, facilitated glucose transporter member 3 1.199e-42 0.33
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.047e-42 0.48
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 1.991e-41 0.44
GTR2_HUMAN SLC2A2 Solute carrier family 2, facilitated glucose transporter member 2 1.092e-40 0.33
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.878e-40 0.34
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 3.362e-39 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 4.672e-38 0.35
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 7.142e-37 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.737e-36 0.36
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 1.027e-33 0.34
SMO_HUMAN SMO Smoothened homolog 2.022e-33 0.43
NK2R_BOVIN TACR2 Substance-K receptor 4.283e-30 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.304e-29 0.51
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 3.269e-29 0.38
HD_HUMAN HTT Huntingtin 1.413e-28 0.43
PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.913e-28 0.37
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 4.454e-28 0.31
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 9.745e-28 0.33
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 2.324e-27 0.45
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.851e-25 0.33
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 7.372e-25 0.47
LDLR_HUMAN LDLR Low-density lipoprotein receptor 3.082e-24 0.34
ATM_HUMAN ATM Serine-protein kinase ATM 1.109e-23 0.31
REV1_HUMAN REV1 DNA repair protein REV1 1.058e-22 0.32
MEN1_HUMAN MEN1 Menin 1.063e-22 0.58
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1.128e-22 0.32
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.361e-22 0.35
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 2.375e-22 0.31
GYRB_MYCSM gyrB DNA gyrase subunit B 2.471e-22 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.693e-22 0.34
O70424_RAT Neuropeptide Y-Y2 receptor 6.61e-22 0.35
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 7.044e-22 0.33
LIMK1_HUMAN LIMK1 LIM domain kinase 1 9.166e-22 0.41
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 2.899e-21 0.30
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 4.683e-21 0.33
PARP6_HUMAN PARP6 Protein mono-ADP-ribosyltransferase PARP6 6.654e-21 0.33
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.146e-20 0.33
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 1.096e-19 0.31
NMT2_HUMAN NMT2 Glycylpeptide N-tetradecanoyltransferase 2 1.193e-19 0.31
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 2.87e-19 0.51
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 4.734e-19 0.35
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 5.013e-19 0.39
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 8.244e-19 0.48
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 4.228e-18 0.35
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.11e-16 0.39
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 1.11e-16 0.45
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 2.22e-16 0.31
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 2.22e-16 0.32
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 3.331e-16 0.35
RET4_HUMAN RBP4 Retinol-binding protein 4 4.441e-16 0.36
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.551e-16 0.33
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 8.882e-16 0.35
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 1.11e-15 0.36
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.443e-15 0.37
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 2.109e-15 0.36
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 2.331e-15 0.40
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 2.331e-15 0.36
V1AR_RAT Avpr1a Vasopressin V1a receptor 2.442e-15 0.35
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.442e-15 0.41
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 2.776e-15 0.29
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.998e-15 0.37
BRS3_RAT Brs3 Bombesin receptor subtype-3 8.993e-15 0.36
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.01e-14 0.48
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 2.021e-14 0.34
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 2.132e-14 0.32
TP53B_HUMAN TP53BP1 TP53-binding protein 1 3.408e-14 0.31
P2RX3_RAT P2rx3 P2X purinoceptor 3 5.651e-14 0.32
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 7.683e-14 0.36
RCE1_YEAST RCE1 CAAX prenyl protease 2 1.9e-13 0.36
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.277e-13 0.38
NMDE2_MOUSE Grin2b Glutamate receptor ionotropic, NMDA 2B 2.749e-13 0.33
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.918e-13 0.35
UT1_RAT Slc14a1 Urea transporter 1 3.741e-13 0.36
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.342e-13 0.33
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 4.352e-13 0.39
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.868e-13 0.39
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.162e-12 0.34
KHK_HUMAN KHK Ketohexokinase 2.442e-12 0.36
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.633e-12 0.33
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 2.687e-12 0.36
PRIO_HUMAN PRNP Major prion protein 3.12e-12 0.38
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 3.93e-12 0.47
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 5.004e-12 0.30
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 5.666e-12 0.31
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 6.076e-12 0.38
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 6.736e-12 0.29
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.111e-11 0.35
AUKBB_XENLA aurkb-b Aurora kinase B-B 1.119e-11 0.28
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.156e-11 0.48
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.32e-11 0.29
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.434e-11 0.36
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.457e-11 0.36
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.594e-11 0.36
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 2.117e-11 0.48
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 2.515e-11 0.32
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 2.579e-11 0.30
GLI1_MOUSE Gli1 Zinc finger protein GLI1 2.953e-11 0.37
GPR6_HUMAN GPR6 G-protein coupled receptor 6 3.929e-11 0.36
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 4.872e-11 0.33
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 6.379e-11 0.31
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 7.588e-11 0.48
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 7.83e-11 0.40
STE24_YEAST STE24 CAAX prenyl protease 1 1.054e-10 0.36
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 1.144e-10 0.30
MTOR_MOUSE Mtor Serine/threonine-protein kinase mTOR 1.258e-10 0.29
NK3R_HUMAN TACR3 Neuromedin-K receptor 2.028e-10 0.34
IL5_MOUSE Il5 Interleukin-5 2.467e-10 0.29
TSHR_HUMAN TSHR Thyrotropin receptor 3.79e-10 0.29
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 5.575e-10 0.29
AURKA_HUMAN AURKA Aurora kinase A 5.622e-10 0.41
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 6.056e-10 0.39
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 8.415e-10 0.32
RHOA_HUMAN RHOA Transforming protein RhoA 1.122e-09 0.29
BAD_HUMAN BAD Bcl2-associated agonist of cell death 1.199e-09 0.30
AURKB_HUMAN AURKB Aurora kinase B 1.3e-09 0.41
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 2.305e-09 0.39
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 2.353e-09 0.33
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 2.619e-09 0.32
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 2.72e-09 0.29
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 3.125e-09 0.29
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.16e-09 0.41
ACES_ELEEL ache Acetylcholinesterase 4.91e-09 0.39
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 5.02e-09 0.30
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 5.02e-09 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 6.243e-09 0.30
SMO_MOUSE Smo Smoothened homolog 6.48e-09 0.34
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 6.492e-09 0.31
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 6.973e-09 0.31
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 7.189e-09 0.31
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 8.308e-09 0.41
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 9.757e-09 0.32
ACOD_HUMAN SCD Acyl-CoA desaturase 1.033e-08 0.34
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 1.042e-08 0.33
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 1.134e-08 0.38
COT2_HUMAN NR2F2 COUP transcription factor 2 1.217e-08 0.35
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.777e-08 0.40
LUCI_RENRE Coelenterazine h 2-monooxygenase 2.195e-08 0.30
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 2.316e-08 0.29
ECR_AEDAE EcR Ecdysone receptor 2.541e-08 0.29
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.55e-08 0.29
DHSO_HUMAN SORD Sorbitol dehydrogenase 2.758e-08 0.39
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.267e-08 0.41
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.731e-08 0.38
IL6_HUMAN IL6 Interleukin-6 3.935e-08 0.32
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.247e-08 0.37
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 5.717e-08 0.37
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 7.516e-08 0.30
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 7.547e-08 0.33
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 7.568e-08 0.36
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 7.813e-08 0.30
LUCI_PHOPY Luciferin 4-monooxygenase 8.711e-08 0.38
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 9.132e-08 0.30
V2R_RAT Avpr2 Vasopressin V2 receptor 9.29e-08 0.35
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.087e-07 0.39
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 1.147e-07 0.30
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 1.155e-07 0.31
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 1.276e-07 0.36
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.55e-07 0.31
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1.849e-07 0.29
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 2.036e-07 0.30
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.318e-07 0.36
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.404e-07 0.38
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 2.541e-07 0.31
DCTP1_HUMAN DCTPP1 dCTP pyrophosphatase 1 2.885e-07 0.34
MITF_HUMAN MITF Microphthalmia-associated transcription factor 3.165e-07 0.36
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 3.731e-07 0.36
LEF_BACAN lef Lethal factor 4.171e-07 0.32
O97467_PLAFA ht1 Hexose transporter 1 4.568e-07 0.32
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 5.112e-07 0.31
O61059_LEIME LmGT2 Glucose transporter 5.118e-07 0.32
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 6.158e-07 0.33
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.347e-06 0.32
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.373e-06 0.35
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.53e-06 0.41
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.549e-06 0.29
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 1.65e-06 0.36
ADK_HUMAN ADK Adenosine kinase 1.772e-06 0.31
TNFA_HUMAN TNF Tumor necrosis factor 2.087e-06 0.36
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 2.145e-06 0.28
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 2.147e-06 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.211e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 2.254e-06 0.31
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.676e-06 0.30
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.812e-06 0.34
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 3.025e-06 0.37
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 3.596e-06 0.33
MGLL_HUMAN MGLL Monoglyceride lipase 3.681e-06 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 3.863e-06 0.30
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 3.885e-06 0.30
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 4.256e-06 0.29
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 4.26e-06 0.32
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 4.548e-06 0.30
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 4.81e-06 0.30
NK3R_RAT Tacr3 Neuromedin-K receptor 5.405e-06 0.29
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 5.616e-06 0.37
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 6.446e-06 0.36
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 7.094e-06 0.30
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 7.216e-06 0.36
DPOL_VACCW POL DNA polymerase 7.705e-06 0.28
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 8.133e-06 0.29
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 8.657e-06 0.33
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 8.723e-06 0.41
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 9.224e-06 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 9.668e-06 0.37