Results of Job: search_4b9a49a4-5b97-4d91-bc8b-384287d65bdd

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 3.038e-124 0.41
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.704e-89 0.49
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 4.523e-75 0.33
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.811e-73 0.39
C3SLB7_ECOLX glmU Bifunctional protein GlmU 7.022e-73 0.35
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 3.922e-71 0.35
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 2.789e-70 0.37
CTNB1_HUMAN CTNNB1 Catenin beta-1 3.137e-69 0.33
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 3.943e-64 0.33
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 7.855e-62 0.35
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 4.692e-55 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.105e-53 0.33
PRIO_SHEEP PRNP Major prion protein 1.982e-50 0.38
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.937e-49 0.35
ENL_HUMAN MLLT1 Protein ENL 1.073e-45 0.29
O31272_9GAMM imiS Beta-lactamase 1.347e-45 0.33
SHH_MOUSE Shh Sonic hedgehog protein 1.877e-43 0.33
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 6.532e-43 0.50
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.153e-42 0.33
TLR4_MOUSE Tlr4 Toll-like receptor 4 7.56e-40 0.38
Q8IL11_PLAF7 M17 leucyl aminopeptidase 3.833e-39 0.43
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.177e-37 0.32
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 6.224e-34 0.40
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 2.751e-33 0.34
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.364e-32 0.34
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.416e-32 0.34
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 2.524e-31 0.31
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 8.968e-31 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.143e-30 0.35
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 1.624e-29 0.40
PRIO_HUMAN PRNP Major prion protein 3.321e-29 0.37
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 4.435e-29 0.36
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 3.829e-28 0.35
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 5.826e-26 0.31
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 7.06e-26 0.32
KC1D_RAT Csnk1d Casein kinase I isoform delta 5.566e-25 0.40
UROK_HUMAN PLAU Urokinase-type plasminogen activator 6.847e-25 0.39
TPA_HUMAN PLAT Tissue-type plasminogen activator 8.941e-25 0.39
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 9.319e-25 0.44
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.371e-24 0.32
TLR4_HUMAN TLR4 Toll-like receptor 4 1.354e-22 0.38
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 8.943e-21 0.36
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 4.558e-20 0.32
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 5.677e-20 0.32
AUKBA_XENLA aurkb-a Aurora kinase B-A 8.909e-20 0.31
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.193e-19 0.31
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.21e-19 0.34
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 2.984e-19 0.31
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 4.261e-19 0.46
LIPL_HUMAN LPL Lipoprotein lipase 9.803e-19 0.30
AURKA_HUMAN AURKA Aurora kinase A 1.917e-18 0.35
RCOR1_HUMAN RCOR1 REST corepressor 1 2.432e-18 0.33
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 3.954e-18 0.37
LIPL_BOVIN LPL Lipoprotein lipase 4.879e-18 0.29
FA9_HUMAN F9 Coagulation factor IX 5.26e-18 0.36
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 6.589e-18 0.35
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.159e-17 0.33
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 1.11e-16 0.31
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 4.441e-16 0.38
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 1.554e-15 0.30
Q9NBA7_PLAFA Cysteine protease falcipain-3 2.442e-15 0.42
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 3.442e-15 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.553e-15 0.36
PAR12_HUMAN PARP12 Protein mono-ADP-ribosyltransferase PARP12 6.772e-15 0.28
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 6.772e-15 0.28
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 9.77e-15 0.37
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.354e-14 0.37
KLK1_HUMAN KLK1 Kallikrein-1 2.52e-14 0.39
EXSA_PSEAE exsA Exoenzyme S synthesis regulatory protein ExsA 3.786e-14 0.29
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 4.197e-14 0.45
Q38C41_TRYB2 Phosphotransferase 5.052e-14 0.31
TERT_HUMAN TERT Telomerase reverse transcriptase 8.149e-14 0.35
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 8.704e-14 0.38
GRIA1_RAT Gria1 Glutamate receptor 1 1.505e-13 0.30
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 2.293e-13 0.31
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 3.396e-13 0.34
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 4.174e-13 0.45
TRY1_HUMAN PRSS1 Trypsin-1 8.101e-13 0.39
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 8.641e-13 0.45
SENP1_HUMAN SENP1 Sentrin-specific protease 1 8.692e-13 0.34
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 9.167e-13 0.37
AURKB_HUMAN AURKB Aurora kinase B 1.174e-12 0.37
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.329e-12 0.38
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.639e-12 0.33
SMO_MOUSE Smo Smoothened homolog 1.709e-12 0.32
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.745e-12 0.33
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 2.397e-12 0.30
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.968e-12 0.33
BXE_CLOBO botE Botulinum neurotoxin type E 3.63e-12 0.30
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 4.089e-12 0.34
FA10_HUMAN F10 Coagulation factor X 4.233e-12 0.39
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 6.081e-12 0.33
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 6.267e-12 0.35
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 7.53e-12 0.32
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 8.956e-12 0.33
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.466e-11 0.34
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.616e-11 0.38
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 1.776e-11 0.33
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 2.1e-11 0.34
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 2.129e-11 0.35
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 3.176e-11 0.30
PLMN_HUMAN PLG Plasminogen 3.539e-11 0.39
IL5_MOUSE Il5 Interleukin-5 6.479e-11 0.31
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 8.381e-11 0.33
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 9.975e-11 0.39
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 1.045e-10 0.41
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.125e-10 0.45
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 1.257e-10 0.28
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 2.062e-10 0.37
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 2.706e-10 0.37
KHK_HUMAN KHK Ketohexokinase 2.8e-10 0.36
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 7.012e-10 0.34
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 9.638e-10 0.28
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.572e-09 0.38
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 1.658e-09 0.33
MEP50_HUMAN WDR77 Methylosome protein 50 1.759e-09 0.33
AA1R_BOVIN ADORA1 Adenosine receptor A1 1.921e-09 0.34
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 2.041e-09 0.36
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 2.18e-09 0.31
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.201e-09 0.33
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 3.151e-09 0.38
PA21B_HUMAN PLA2G1B Phospholipase A2 3.629e-09 0.41
ACES_ELEEL ache Acetylcholinesterase 3.798e-09 0.35
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 4.107e-09 0.42
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 4.384e-09 0.31
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.519e-09 0.42
THRB_HUMAN F2 Prothrombin 6.955e-09 0.39
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 8.278e-09 0.30
VE1_HPV11 E1 Replication protein E1 9.027e-09 0.31
TRYP_PIG Trypsin 1.131e-08 0.39
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.526e-08 0.33
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 1.976e-08 0.33
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 2.572e-08 0.29
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 2.691e-08 0.33
IL6_HUMAN IL6 Interleukin-6 3.82e-08 0.32
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 4.358e-08 0.46
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 4.559e-08 0.42
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 4.633e-08 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 4.839e-08 0.34
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 5.05e-08 0.38
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 5.565e-08 0.40
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 6.847e-08 0.35
FA7_HUMAN F7 Coagulation factor VII 8.735e-08 0.38
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 9.153e-08 0.32
PERM_HUMAN MPO Myeloperoxidase 1.492e-07 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.717e-07 0.32
ITB3_HUMAN ITGB3 Integrin beta-3 1.896e-07 0.34
POLG_DEN2P Genome polyprotein 2.27e-07 0.32
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.607e-07 0.35
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 3.013e-07 0.31
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 3.78e-07 0.32
TNFA_HUMAN TNF Tumor necrosis factor 4.112e-07 0.37
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 4.575e-07 0.33
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.905e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.905e-07 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.996e-07 0.34
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 5.215e-07 0.37
DYR_HUMAN DHFR Dihydrofolate reductase 5.808e-07 0.36
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 6.26e-07 0.37
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 6.537e-07 0.34
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 7.046e-07 0.35
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 7.834e-07 0.29
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 8.17e-07 0.34
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 8.63e-07 0.31
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.16e-06 0.39
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 1.189e-06 0.34
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.277e-06 0.29
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.323e-06 0.40
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 1.35e-06 0.36
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.418e-06 0.30
HSF1_MOUSE Hsf1 Heat shock factor protein 1 1.482e-06 0.38
KLK7_HUMAN KLK7 Kallikrein-7 1.532e-06 0.38
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 1.831e-06 0.29
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.432e-06 0.43
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.611e-06 0.29
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.849e-06 0.29
SCAF_HCMVA UL80 Capsid scaffolding protein 2.926e-06 0.33
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 3.018e-06 0.29
RECA_MYCTU recA Protein RecA 3.232e-06 0.44
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.236e-06 0.34
LEF_BACAN lef Lethal factor 3.583e-06 0.33
STRP_STRP1 ska Streptokinase A 3.62e-06 0.49
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.624e-06 0.37
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 3.628e-06 0.31
LUCI_AQULA Luciferin 4-monooxygenase 3.683e-06 0.30
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.723e-06 0.37
TF_HUMAN F3 Tissue factor 4.108e-06 0.32
HDA11_HUMAN HDAC11 Histone deacetylase 11 4.114e-06 0.35
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 4.267e-06 0.31
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 4.267e-06 0.31
GYRA_STAAU gyrA DNA gyrase subunit A 4.28e-06 0.34
KISSR_HUMAN KISS1R KiSS-1 receptor 5.349e-06 0.33
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 5.99e-06 0.29
PLEC_HUMAN PLEC Plectin 6.029e-06 0.30
CCKAR_RAT Cckar Cholecystokinin receptor type A 6.147e-06 0.41
PTGES_HUMAN PTGES Prostaglandin E synthase 6.596e-06 0.39
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 6.871e-06 0.38
HPSE_HUMAN HPSE Heparanase 6.924e-06 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 7.62e-06 0.33
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.797e-06 0.35
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 9.307e-06 0.32
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 9.401e-06 0.35