Results of Job: search_503ca215-49b2-4fc2-b50b-10a20673234a

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 8.464e-185 0.62
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.655e-90 0.44
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 5.11e-88 0.39
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.487e-87 0.38
C3SLB7_ECOLX glmU Bifunctional protein GlmU 8.404e-68 0.42
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 9.131e-54 0.30
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.161e-51 0.33
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 5.935e-48 0.32
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.204e-43 0.49
TLR4_MOUSE Tlr4 Toll-like receptor 4 5.958e-42 0.39
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.777e-38 0.41
ATM_HUMAN ATM Serine-protein kinase ATM 1.803e-34 0.34
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 4.522e-30 0.36
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 5.901e-30 0.33
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 1.218e-29 0.31
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.448e-28 0.36
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.37e-28 0.33
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 5.245e-27 0.33
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.099e-26 0.37
KC1D_RAT Csnk1d Casein kinase I isoform delta 5.638e-25 0.39
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 8.537e-25 0.35
Q8IL11_PLAF7 M17 leucyl aminopeptidase 1.846e-24 0.40
PRIO_HUMAN PRNP Major prion protein 7.084e-24 0.36
TLR4_HUMAN TLR4 Toll-like receptor 4 7.382e-24 0.39
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.237e-23 0.41
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 2.063e-23 0.29
MET_HUMAN MET Hepatocyte growth factor receptor 8.903e-23 0.39
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 5.604e-22 0.32
AUKBA_XENLA aurkb-a Aurora kinase B-A 7.766e-22 0.35
NTR2_RAT Ntsr2 Neurotensin receptor type 2 3.109e-21 0.29
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.011e-19 0.33
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.523e-19 0.39
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.594e-19 0.36
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.523e-18 0.29
SHH_MOUSE Shh Sonic hedgehog protein 1.677e-18 0.35
UHRF1_HUMAN UHRF1 E3 ubiquitin-protein ligase UHRF1 2.898e-18 0.29
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 8.756e-18 0.37
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.115e-17 0.33
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 1.433e-17 0.47
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 5.452e-17 0.36
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.11e-16 0.35
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 3.331e-16 0.46
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 5.551e-16 0.34
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 8.882e-16 0.34
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.498e-14 0.48
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.651e-14 0.40
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 6.306e-14 0.33
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.007e-13 0.29
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.027e-13 0.30
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 2.77e-13 0.37
CASB_RAT Csn2 Beta-casein 3.285e-13 0.29
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.277e-13 0.44
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 7.114e-13 0.34
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.066e-12 0.33
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.013e-12 0.33
PA21B_HUMAN PLA2G1B Phospholipase A2 2.345e-12 0.47
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 2.755e-12 0.33
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 3.544e-12 0.39
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 3.8e-12 0.33
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 7.107e-12 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 2.636e-11 0.36
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.309e-11 0.39
A5H660_SCHMA HDAC8 Histone deacetylase 8 4.609e-11 0.32
Q9NBA7_PLAFA Cysteine protease falcipain-3 6.023e-11 0.29
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 7.187e-11 0.36
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 7.975e-11 0.32
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 9.455e-11 0.29
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 9.585e-11 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 1.73e-10 0.30
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.271e-10 0.36
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 2.989e-10 0.34
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.031e-10 0.39
ACES_TETCF ache Acetylcholinesterase 6.895e-10 0.30
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 9.284e-10 0.32
MEP50_HUMAN WDR77 Methylosome protein 50 1.342e-09 0.32
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.683e-09 0.32
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 3.598e-09 0.29
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 4.045e-09 0.32
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 6.066e-09 0.43
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 7.568e-09 0.31
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 8.029e-09 0.30
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 9.327e-09 0.38
PERM_HUMAN MPO Myeloperoxidase 9.372e-09 0.43
EGFR_HUMAN EGFR Epidermal growth factor receptor 9.428e-09 0.38
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 2.139e-08 0.41
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.158e-08 0.37
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 2.36e-08 0.32
ACES_BOVIN ACHE Acetylcholinesterase 2.461e-08 0.32
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.659e-08 0.40
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 4.616e-08 0.31
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 5.387e-08 0.39
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 5.562e-08 0.31
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 6.121e-08 0.35
ACES_ELEEL ache Acetylcholinesterase 7.082e-08 0.36
SMO_HUMAN SMO Smoothened homolog 9.604e-08 0.35
AURKB_HUMAN AURKB Aurora kinase B 1.271e-07 0.39
BGLR_HUMAN GUSB Beta-glucuronidase 1.298e-07 0.30
DYR_HUMAN DHFR Dihydrofolate reductase 1.786e-07 0.33
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.001e-07 0.35
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 2.647e-07 0.29
DRD1_PIG DRD1 D(1A) dopamine receptor 2.81e-07 0.30
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.32e-07 0.49
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 3.561e-07 0.38
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 4.136e-07 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 4.232e-07 0.37
AA3R_HUMAN ADORA3 Adenosine receptor A3 4.302e-07 0.33
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 5.339e-07 0.30
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 6.923e-07 0.30
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 7.02e-07 0.37
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 8.061e-07 0.30
AURKA_HUMAN AURKA Aurora kinase A 1.108e-06 0.39
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.182e-06 0.31
UREA_CANEN Urease 1.222e-06 0.30
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.328e-06 0.35
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 1.348e-06 0.30
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 1.728e-06 0.32
PRIO_SHEEP PRNP Major prion protein 1.894e-06 0.29
KLK5_HUMAN KLK5 Kallikrein-5 2.185e-06 0.29
HDA11_HUMAN HDAC11 Histone deacetylase 11 2.337e-06 0.37
DPOL_VACCW POL DNA polymerase 2.343e-06 0.31
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.409e-06 0.29
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 2.444e-06 0.29
KLK7_HUMAN KLK7 Kallikrein-7 2.477e-06 0.37
STRP_STRP1 ska Streptokinase A 2.526e-06 0.47
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 2.694e-06 0.34
GPR55_HUMAN GPR55 G-protein coupled receptor 55 2.758e-06 0.39
XBP1_HUMAN XBP1 X-box-binding protein 1 2.877e-06 0.35
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 3.245e-06 0.33
TIE2_HUMAN TEK Angiopoietin-1 receptor 3.266e-06 0.34
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.91e-06 0.29
GRIA1_RAT Gria1 Glutamate receptor 1 4.309e-06 0.29
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 5.02e-06 0.29
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 5.137e-06 0.40
THAS_HUMAN TBXAS1 Thromboxane-A synthase 5.204e-06 0.30
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 5.273e-06 0.46
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 5.619e-06 0.31
LUCI_AQULA Luciferin 4-monooxygenase 5.99e-06 0.29
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 8.723e-06 0.40
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 8.747e-06 0.30
TNFA_HUMAN TNF Tumor necrosis factor 9.738e-06 0.34