Results of Job: search_50583d5d-397e-4103-b162-7fad82fc7363

Query Target Key Target Name Description P-Value MaxTC

compound_1

TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 7.024e-122 0.39
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.144e-112 0.39
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 3.506e-87 0.43
WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.472e-79 0.38
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 4.098e-78 0.38
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 2.199e-67 0.32
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 4.557e-53 0.35
HDAC1_HUMAN HDAC1 Histone deacetylase 1 8.38e-51 0.47
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.809e-38 0.31
PARE_ECOLI parE DNA topoisomerase 4 subunit B 2.89e-37 0.30
PRIO_SHEEP PRNP Major prion protein 1.259e-36 0.34
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.693e-36 0.61
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 3.875e-36 0.29
TBA_TRYCR Tubulin alpha chain 4.527e-36 0.30
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 1.308e-34 0.33
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 3.972e-34 0.37
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 4.097e-33 0.40
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 7.954e-32 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.213e-31 0.34
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 4.91e-31 0.38
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 7.068e-29 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.265e-26 0.43
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 5.388e-24 0.31
SENP1_HUMAN SENP1 Sentrin-specific protease 1 8.417e-24 0.33
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.28e-22 0.30
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 2.903e-22 0.33
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 2.322e-21 0.32
SHH_MOUSE Shh Sonic hedgehog protein 5.14e-21 0.41
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 3.267e-20 0.31
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.193e-19 0.31
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.26e-19 0.35
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 4.514e-19 0.34
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 2.749e-18 0.29
LIPL_HUMAN LPL Lipoprotein lipase 4.879e-18 0.29
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 5.273e-18 0.64
ABCC9_HUMAN ABCC9 ATP-binding cassette sub-family C member 9 5.436e-18 0.44
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 6.643e-18 0.29
FNTB_BOVIN FNTB Protein farnesyltransferase subunit beta 6.806e-18 0.39
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.904e-17 0.43
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.949e-17 0.35
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 2.406e-17 0.37
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.006e-17 0.38
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 1.11e-16 0.40
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.11e-16 0.35
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 2.22e-16 0.36
THAS_HUMAN TBXAS1 Thromboxane-A synthase 4.441e-16 0.33
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 6.661e-16 0.33
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.665e-15 0.40
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 2.442e-15 0.37
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 5.107e-15 0.39
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 6.106e-15 0.46
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 1.077e-14 0.44
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.088e-14 0.41
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.144e-14 0.36
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.787e-14 0.39
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.565e-14 0.56
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 5.984e-14 0.41
NR1H4_HUMAN NR1H4 Bile acid receptor 4.468e-13 0.37
A6QR73_RAT Gpr39 G protein-coupled receptor 39 1.157e-12 0.31
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.171e-12 0.28
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.774e-12 0.34
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.563e-12 0.46
VHL_HUMAN VHL von Hippel-Lindau disease tumor suppressor 3.778e-12 0.32
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 4.492e-12 0.41
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 6.868e-12 0.40
LYOX_HUMAN LOX Protein-lysine 6-oxidase 7.001e-12 0.32
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 7.983e-12 0.40
AURKB_HUMAN AURKB Aurora kinase B 8e-12 0.35
LDLR_HUMAN LDLR Low-density lipoprotein receptor 8.356e-12 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.32e-11 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.481e-11 0.41
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.565e-11 0.34
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 1.999e-11 0.38
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 2.893e-11 0.34
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.692e-11 0.41
AURKA_HUMAN AURKA Aurora kinase A 3.84e-11 0.35
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 7.652e-11 0.37
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.119e-10 0.44
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.384e-10 0.44
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.441e-10 0.33
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.478e-10 0.40
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.658e-10 0.31
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.832e-10 0.29
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 2.195e-10 0.33
ACOD_HUMAN SCD Acyl-CoA desaturase 2.411e-10 0.40
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 2.5e-10 0.34
PA_I34A1 PA Polymerase acidic protein 2.65e-10 0.30
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.337e-10 0.31
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.453e-10 0.37
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 5.782e-10 0.39
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 6.094e-10 0.38
CYNT_HELPY cynT Carbonic anhydrase 8.099e-10 0.30
TPOR_HUMAN MPL Thrombopoietin receptor 1.199e-09 0.36
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.57e-09 0.38
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.949e-09 0.33
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 2.244e-09 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.38e-09 0.33
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 2.466e-09 0.33
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 3.024e-09 0.33
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 5.897e-09 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 8.99e-09 0.39
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 1.04e-08 0.33
PARE_STAAU parE DNA topoisomerase 4 subunit B 1.091e-08 0.30
TNFA_HUMAN TNF Tumor necrosis factor 1.138e-08 0.36
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.204e-08 0.31
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.208e-08 0.35
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.332e-08 0.33
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.506e-08 0.31
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 1.613e-08 0.32
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.618e-08 0.35
DNAB_MYCTU dnaB Replicative DNA helicase 1.829e-08 0.64
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 2.513e-08 0.34
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 2.589e-08 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.633e-08 0.41
RECA_MYCTU recA Protein RecA 3.089e-08 0.64
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.232e-08 0.34
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 4.134e-08 0.43
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 4.413e-08 0.32
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 4.472e-08 0.29
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 4.68e-08 0.31
ACHP_LYMST Acetylcholine-binding protein 6.905e-08 0.31
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 7.05e-08 0.30
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 8.201e-08 0.32
KLF5_HUMAN KLF5 Krueppel-like factor 5 8.506e-08 0.39
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 9.132e-08 0.29
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 9.208e-08 0.33
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 9.381e-08 0.33
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.046e-07 0.33
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 1.11e-07 0.38
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.175e-07 0.34
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.264e-07 0.31
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.264e-07 0.31
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.624e-07 0.41
KCNH3_HUMAN KCNH3 Potassium voltage-gated channel subfamily H member 3 2.089e-07 0.31
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.494e-07 0.41
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 2.514e-07 0.40
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.681e-07 0.41
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 3.373e-07 0.31
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.583e-07 0.40
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.608e-07 0.39
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 3.809e-07 0.39
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 5.033e-07 0.37
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 6.148e-07 0.28
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 6.358e-07 0.33
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 6.815e-07 0.32
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 6.901e-07 0.34
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 7.597e-07 0.34
FA10_HUMAN F10 Coagulation factor X 8.227e-07 0.47
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 8.605e-07 0.33
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 8.63e-07 0.31
POLG_DEN2P Genome polyprotein 9.396e-07 0.29
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.148e-06 0.33
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.172e-06 0.35
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.458e-06 0.33
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.494e-06 0.30
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.605e-06 0.35
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.683e-06 0.29
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.774e-06 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.943e-06 0.31
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.121e-06 0.36
HDAC1_MOUSE Hdac1 Histone deacetylase 1 2.141e-06 0.32
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.164e-06 0.31
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.234e-06 0.30
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 2.265e-06 0.31
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 2.462e-06 0.30
HPSE_HUMAN HPSE Heparanase 2.51e-06 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 2.533e-06 0.36
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.58e-06 0.41
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 2.692e-06 0.33
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.718e-06 0.28
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.477e-06 0.28
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 3.536e-06 0.34
AOFB_RAT Maob Amine oxidase [flavin-containing] B 3.553e-06 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 3.606e-06 0.32
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 3.862e-06 0.36
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 3.903e-06 0.33
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 4.027e-06 0.41
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.115e-06 0.33
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 4.128e-06 0.43
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 4.37e-06 0.34
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 4.513e-06 0.40
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 4.687e-06 0.30
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.993e-06 0.28
LUCI_AQULA Luciferin 4-monooxygenase 5.875e-06 0.29
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 6.365e-06 0.32
STABP_HUMAN STAMBP STAM-binding protein 7.094e-06 0.30
HDAC5_HUMAN HDAC5 Histone deacetylase 5 7.171e-06 0.36
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 7.334e-06 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 7.589e-06 0.32
GPR39_HUMAN GPR39 G-protein coupled receptor 39 7.756e-06 0.33
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 8.295e-06 0.40
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 8.433e-06 0.33
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 8.466e-06 0.34
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 8.606e-06 0.35
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 8.715e-06 0.31
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 9.141e-06 0.37