Results of Job: search_523f75de-37c1-4f6a-8c48-81f7cce2b2d1

Query Target Key Target Name Description P-Value MaxTC

compound_3

PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 4.416e-154 1.00
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 8.504e-95 1.00
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 1.007e-90 1.00
PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 6.048e-56 1.00
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 1.11e-16 1.00
E1BN64_BOVIN PDE3B Phosphodiesterase 1.827e-12 0.44
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.159e-09 0.33
SSR3_MOUSE Sstr3 Somatostatin receptor type 3 1.631e-09 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 5.966e-09 0.35
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 8.428e-09 0.47
MGLL_RAT Mgll Monoglyceride lipase 2.52e-08 0.28
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.494e-07 0.29
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 1.715e-07 0.32
EDNRB_PIG EDNRB Endothelin receptor type B 1.425e-06 0.30
EDNRA_RAT Ednra Endothelin-1 receptor 1.492e-06 0.31
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 6.814e-06 0.30
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 7.955e-06 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 9.861e-06 0.33

compound_4

PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 6.126e-153 1.00
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.728e-55 1.00
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 2.55e-81 0.59
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.934e-54 0.39
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 6.08e-53 0.39
CTNB1_HUMAN CTNNB1 Catenin beta-1 3.384e-50 0.39
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.049e-44 0.41
DRD2_CANLF DRD2 D(2) dopamine receptor 1.857e-41 0.34
ST1E1_MOUSE Sult1e1 Estrogen sulfotransferase, testis isoform 1.609e-34 0.28
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 3.526e-29 0.30
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 6.601e-28 0.38
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 4.64e-23 0.41
DRD2_RAT Drd2 D(2) dopamine receptor 3.174e-20 0.36
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.4e-20 0.32
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 8.433e-19 0.34
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.422e-18 0.32
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 3.331e-16 0.37
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 4.441e-16 0.36
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 1.332e-15 0.32
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 1.443e-15 0.34
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.109e-15 0.39
OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.665e-15 0.39
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 2.887e-15 0.34
FAK1_HUMAN PTK2 Focal adhesion kinase 1 3.22e-15 0.35
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.943e-14 0.50
OX1R_HUMAN HCRTR1 Orexin receptor type 1 2.165e-14 0.39
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 3.397e-14 0.34
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 9.837e-14 0.31
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.554e-13 0.32
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.25e-13 0.32
ITB7_HUMAN ITGB7 Integrin beta-7 2.833e-13 0.33
PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 2.933e-13 0.34
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 3.602e-13 0.37
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 6.587e-13 0.33
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 7.726e-13 0.34
DPOL_HCMVA UL54 DNA polymerase catalytic subunit 8.08e-13 0.36
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 9.316e-13 0.31
EZRI_HUMAN EZR Ezrin 1.824e-12 0.31
DRD3_RAT Drd3 D(3) dopamine receptor 3.027e-12 0.32
ABCBB_RAT Abcb11 Bile salt export pump 3.3e-12 0.34
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 4.412e-12 0.33
WNT3A_HUMAN WNT3A Protein Wnt-3a 5.308e-12 0.30
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 6.922e-12 0.30
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 9.95e-12 0.38
ACOD_HUMAN SCD Acyl-CoA desaturase 1.419e-11 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.924e-11 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.226e-11 0.33
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.391e-10 0.33
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 2.198e-10 0.30
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.259e-10 0.33
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 2.521e-10 0.28
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.608e-10 0.37
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 8.046e-10 0.34
ACES_ANOGA Ace Acetylcholinesterase 1.468e-09 0.29
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 1.967e-09 0.35
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 3.422e-09 0.33
AA1R_MOUSE Adora1 Adenosine receptor A1 3.847e-09 0.29
CASR_HUMAN CASR Extracellular calcium-sensing receptor 4.619e-09 0.33
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 8.524e-09 0.34
DPOL_HHV6U U38 DNA polymerase catalytic subunit 9.991e-09 0.34
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.259e-08 0.33
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 3.158e-08 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.97e-08 0.41
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 6.522e-08 0.35
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 6.812e-08 0.36
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1.45e-07 0.30
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 1.662e-07 0.29
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 1.731e-07 0.32
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.793e-07 0.33
DRD3_CHLAE DRD3 D(3) dopamine receptor 2.665e-07 0.31
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 2.975e-07 0.33
GRK5_HUMAN GRK5 G protein-coupled receptor kinase 5 3.02e-07 0.30
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 5.087e-07 0.36
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 9.11e-07 0.29
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 1.083e-06 0.34
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.564e-06 0.30
AA3R_MOUSE Adora3 Adenosine receptor A3 1.743e-06 0.29
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2.951e-06 0.28
AURKA_HUMAN AURKA Aurora kinase A 3.247e-06 0.33
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 3.643e-06 0.33
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 4.121e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.361e-06 0.30
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 5.885e-06 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 9.473e-06 0.33

compound_2

PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 7.15e-145 1.00
PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 1.36e-122 1.00
PDE6C_BOVIN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 6.875e-120 1.00
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 4.989e-115 1.00
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 1.978e-37 1.00
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 2.662e-34 1.00
E1BN64_BOVIN PDE3B Phosphodiesterase 2.472e-27 1.00
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 1.11e-16 1.00
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 4.531e-13 1.00
PDE9A_HUMAN PDE9A High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 1.032e-08 1.00
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.543e-07 1.00
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 7.684e-06 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0003401 1.00
PDE4A_HUMAN PDE4A cAMP-specific 3',5'-cyclic phosphodiesterase 4A 0.001424 1.00
PDE7A_HUMAN PDE7A High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 0.005496 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.01864 1.00
AA1R_HUMAN ADORA1 Adenosine receptor A1 0.0629 1.00
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 0.2615 1.00
MRP5_HUMAN ABCC5 Multidrug resistance-associated protein 5 3.224e-87 0.65
PDE6A_CANLF PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 4.452e-70 0.41
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 8.642e-25 0.32
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 3.215e-19 0.32
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 5.854e-13 0.31
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1.025e-11 0.30
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.39e-10 0.78
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.929e-10 0.68
MCLN3_HUMAN MCOLN3 Mucolipin-3 6.538e-10 0.56
AA1R_RAT Adora1 Adenosine receptor A1 8.963e-10 0.39
AA2BR_MOUSE Adora2b Adenosine receptor A2b 6.279e-09 0.31
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 2.079e-08 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.876e-08 0.68
BGLR_HUMAN GUSB Beta-glucuronidase 4.365e-08 0.35
AA2AR_RAT Adora2a Adenosine receptor A2a 1.481e-06 0.32
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.928e-06 0.32
PDE7B_HUMAN PDE7B cAMP-specific 3',5'-cyclic phosphodiesterase 7B 3.275e-06 0.30

compound_1

IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 2.498e-221 0.53
COLA_CLOPE colA Collagenase ColA 1.33e-41 0.38
KMO_RAT Kmo Kynurenine 3-monooxygenase 7.083e-41 0.44
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 3.859e-40 0.33
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 5.738e-34 0.33
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.353e-31 0.42
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 7.335e-30 0.42
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.686e-26 0.39
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 4.344e-23 0.29
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 6.9e-21 0.42
BKRB2_RAT Bdkrb2 B2 bradykinin receptor 7.208e-18 0.31
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.332e-15 0.33
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.61e-14 0.39
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 3.664e-14 0.37
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.841e-14 0.40
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 9.87e-14 0.32
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.106e-11 0.29
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.677e-11 0.31
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 1.782e-11 0.29
CYSP_TRYCR Cruzipain 1.045e-10 0.52
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 5.337e-10 0.37
TPOR_HUMAN MPL Thrombopoietin receptor 9.09e-10 0.39
PTGES_HUMAN PTGES Prostaglandin E synthase 6.808e-09 0.39
AROQ_STRCO aroQ 3-dehydroquinate dehydratase 8.249e-09 0.28
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 9.637e-09 0.40
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 1.149e-08 0.35
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 1.432e-08 0.29
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 3.08e-08 0.40
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 1.465e-07 0.41
METC_ECOLI metC Cystathionine beta-lyase MetC 3.705e-07 0.29
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 3.794e-07 0.30
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 5.755e-07 0.29
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 9.353e-07 0.31
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 1.203e-06 0.37
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 1.925e-06 0.32
RORG_HUMAN RORC Nuclear receptor ROR-gamma 4.108e-06 0.38
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 4.251e-06 0.39
STRP_STRP1 ska Streptokinase A 7.035e-06 0.41
HDAC9_HUMAN HDAC9 Histone deacetylase 9 9.608e-06 0.32

compound_5

PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 9.196e-128 0.60
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 9.938e-118 0.68
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 1.265e-91 0.64
MRP5_HUMAN ABCC5 Multidrug resistance-associated protein 5 7.921e-78 0.57
PDE6C_BOVIN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 5.337e-72 0.60
PDE6A_CANLF PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 2.265e-56 0.33
DRD2_CANLF DRD2 D(2) dopamine receptor 1.037e-34 0.28
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 8.028e-26 0.33
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 4.73e-24 0.64
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 8.043e-21 0.60
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 5.184e-20 0.33
E1BN64_BOVIN PDE3B Phosphodiesterase 1.11e-16 0.60
CASP3_HUMAN CASP3 Caspase-3 3.077e-11 0.32
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 1.532e-10 0.31
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 3.26e-10 0.60
CASP7_HUMAN CASP7 Caspase-7 9.566e-10 0.32
CASP9_HUMAN CASP9 Caspase-9 1.109e-09 0.30
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 1.311e-09 0.64
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.084e-08 0.55
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 4.276e-08 0.30
BRPF3_HUMAN BRPF3 Bromodomain and PHD finger-containing protein 3 8.42e-08 0.28
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.675e-07 0.41
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 4.121e-06 0.29
PDE9A_HUMAN PDE9A High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 4.685e-06 0.64
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 4.976e-06 0.30
PDE7B_HUMAN PDE7B cAMP-specific 3',5'-cyclic phosphodiesterase 7B 5.789e-06 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 6.151e-06 0.41