Results of Job: search_52a29412-0efe-4611-a2aa-ab866aba4452

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 6.266e-178 0.62
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 3.022e-72 0.38
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.364e-70 0.42
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 4.673e-68 0.35
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 1.947e-62 0.33
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 4.801e-61 0.38
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.253e-49 0.32
D4ADR1_RAT Lpar5 Lysophosphatidic acid receptor 5 1.431e-47 0.38
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 8.918e-47 0.34
CASB_RAT Csn2 Beta-casein 2.283e-42 0.34
MET_HUMAN MET Hepatocyte growth factor receptor 1.206e-41 0.39
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.303e-41 0.38
VDAC2_HUMAN VDAC2 Voltage-dependent anion-selective channel protein 2 3.824e-40 0.32
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 5.622e-38 0.41
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 1.3e-37 0.30
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 4.488e-36 0.33
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 8.446e-36 0.39
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.134e-30 0.37
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 2.827e-30 0.33
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.777e-28 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.811e-28 0.45
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 2.903e-28 0.29
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 2e-27 0.36
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 2.4e-27 0.34
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.417e-27 0.35
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 5.262e-27 0.37
Q93EK7_NEIME lgtC LgtC 7.695e-26 0.29
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 5.639e-25 0.39
KC1D_RAT Csnk1d Casein kinase I isoform delta 1.561e-24 0.39
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 8.715e-24 0.35
TLR4_HUMAN TLR4 Toll-like receptor 4 9.918e-24 0.38
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 2.534e-23 0.30
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 3.915e-23 0.28
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.875e-23 0.31
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 1.211e-22 0.34
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.659e-22 0.45
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.734e-21 0.30
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 1.81e-20 0.31
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.063e-19 0.45
AUKBA_XENLA aurkb-a Aurora kinase B-A 4.226e-19 0.30
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.523e-18 0.29
ABHDB_HUMAN ABHD11 Protein ABHD11 2.749e-18 0.29
ECE2_HUMAN ECE2 Endothelin-converting enzyme 2 3.615e-18 0.29
CFAD_HUMAN CFD Complement factor D 2.422e-17 0.36
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.13e-17 0.37
Q8IL11_PLAF7 M17 leucyl aminopeptidase 4.441e-16 0.39
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.998e-15 0.29
NTR2_RAT Ntsr2 Neurotensin receptor type 2 6.883e-15 0.30
ACES_ELEEL ache Acetylcholinesterase 7.105e-15 0.35
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.177e-14 0.33
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.32e-14 0.33
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 2.687e-14 0.45
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 5.24e-14 0.36
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 9.381e-14 0.31
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 1.067e-13 0.34
HGF_HUMAN HGF Hepatocyte growth factor 3.333e-13 0.29
MIP_LEGPN mip Outer membrane protein MIP 3.981e-13 0.30
CHLE_HORSE BCHE Cholinesterase 4.807e-13 0.32
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 4.913e-13 0.35
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 6.818e-13 0.29
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.126e-12 0.34
TNFA_HUMAN TNF Tumor necrosis factor 2.994e-12 0.34
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 6.736e-12 0.29
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.242e-11 0.30
RCE1_YEAST RCE1 CAAX prenyl protease 2 1.25e-11 0.35
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 1.339e-11 0.28
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 1.339e-11 0.28
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.617e-11 0.30
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 2.618e-11 0.30
Q9JKC1_RAT Bche Carboxylic ester hydrolase 3.654e-11 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 4.104e-11 0.39
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 4.694e-11 0.36
ACES_RAT Ache Acetylcholinesterase 6.659e-11 0.33
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 7.6e-11 0.31
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 7.946e-11 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 1.116e-10 0.32
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.3e-10 0.46
HRH3_HUMAN HRH3 Histamine H3 receptor 1.425e-10 0.38
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.456e-10 0.36
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.479e-10 0.28
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.89e-10 0.36
PA21B_HUMAN PLA2G1B Phospholipase A2 3.455e-10 0.45
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 5.927e-10 0.37
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 6.458e-10 0.46
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 7.004e-10 0.36
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 8.757e-10 0.33
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 1.147e-09 0.30
MCLN3_HUMAN MCOLN3 Mucolipin-3 1.24e-09 0.38
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.718e-09 0.46
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.943e-09 0.45
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 2.129e-09 0.33
PRIO_HUMAN PRNP Major prion protein 2.365e-09 0.33
RON_HUMAN MST1R Macrophage-stimulating protein receptor 3.155e-09 0.32
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 4.884e-09 0.31
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 5.382e-09 0.36
SHH_MOUSE Shh Sonic hedgehog protein 5.426e-09 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 5.568e-09 0.34
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 5.664e-09 0.40
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 6.128e-09 0.38
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.231e-08 0.34
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.679e-08 0.32
NDKB_HUMAN NME2 Nucleoside diphosphate kinase B 1.751e-08 0.28
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.875e-08 0.33
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 2.128e-08 0.30
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.447e-08 0.41
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 3.274e-08 0.33
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 3.389e-08 0.31
ACES_HUMAN ACHE Acetylcholinesterase 3.756e-08 0.35
LIPS_RAT Lipe Hormone-sensitive lipase 4.651e-08 0.31
SDHB_HUMAN SDHB Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial 5.379e-08 0.31
PDE8A_HUMAN PDE8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 5.822e-08 0.30
BGLR_HUMAN GUSB Beta-glucuronidase 1.298e-07 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.35e-07 0.36
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.795e-07 0.31
MOT1_RAT Slc16a1 Monocarboxylate transporter 1 3.542e-07 0.30
PERM_HUMAN MPO Myeloperoxidase 6.856e-07 0.36
Q5TKS5_STAAU fabI Enoyl-ACP reductase 7.921e-07 0.32
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 8.402e-07 0.39
DYR_HUMAN DHFR Dihydrofolate reductase 8.468e-07 0.32
ACES_BOVIN ACHE Acetylcholinesterase 8.514e-07 0.34
GPR55_HUMAN GPR55 G-protein coupled receptor 55 9.091e-07 0.37
FDFT_HUMAN FDFT1 Squalene synthase 1.119e-06 0.35
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.182e-06 0.31
ACES_TETCF ache Acetylcholinesterase 1.36e-06 0.29
PDE6C_HUMAN PDE6C Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 1.453e-06 0.29
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.499e-06 0.42
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.553e-06 0.32
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.151e-06 0.33
ATM_HUMAN ATM Serine-protein kinase ATM 2.298e-06 0.31
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 2.342e-06 0.37
CHLE_HUMAN BCHE Cholinesterase 3.828e-06 0.35
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.91e-06 0.29
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 4.003e-06 0.45
NK2R_MOUSE Tacr2 Substance-K receptor 4.51e-06 0.30
FDFT_RAT Fdft1 Squalene synthase 5.1e-06 0.29
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 6.158e-06 0.31
GP183_MOUSE Gpr183 G-protein coupled receptor 183 7.371e-06 0.31
DPOL_VACCW POL DNA polymerase 8.833e-06 0.28
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 8.925e-06 0.30
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 8.965e-06 0.28
TSPO_RAT Tspo Translocator protein 9.322e-06 0.31
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 9.389e-06 0.42