Results of Job: search_56befcb7-056d-4d4c-90ed-9a341e78bb1a

Query Target Key Target Name Description P-Value MaxTC

Asciminib

ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.691e-213 1.00
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 2.311e-41 0.31
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 2.643e-36 0.31
TPOR_HUMAN MPL Thrombopoietin receptor 1.631e-33 0.35
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 3.726e-25 0.36
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2.601e-24 0.34
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 5.82e-23 0.34
PRIO_SHEEP PRNP Major prion protein 7.214e-23 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.847e-19 0.36
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.375e-18 0.32
LIPL_BOVIN LPL Lipoprotein lipase 3.886e-18 0.29
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 7.91e-18 0.30
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 1.11e-16 0.32
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 9.992e-16 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.088e-14 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.862e-13 0.34
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 3.385e-13 0.34
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 7.936e-13 0.29
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 3.439e-12 0.31
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.15e-10 0.32
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 6.69e-10 0.29
MTAP2_HUMAN MAP2 Microtubule-associated protein 2 1.026e-09 0.31
GLR_HUMAN GCGR Glucagon receptor 2.998e-09 0.32
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.871e-08 0.37
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.318e-08 0.32
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 5.393e-08 0.38
SHH_MOUSE Shh Sonic hedgehog protein 8.166e-08 0.33
MYO3B_HUMAN MYO3B Myosin-IIIb 2.164e-07 0.29
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 6.114e-07 0.30
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 6.644e-07 0.32
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 8.459e-07 0.32
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 8.635e-07 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 9.148e-07 0.32
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.011e-06 0.32
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.102e-06 0.31
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.106e-06 0.28
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.106e-06 0.28
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.56e-06 0.29
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.867e-06 0.30
LIPS_HUMAN LIPE Hormone-sensitive lipase 2.952e-06 0.33
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 3.263e-06 0.30
Q8VBU5_MOUSE Pde4b Phosphodiesterase 3.371e-06 0.31
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.488e-06 0.29
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 4.188e-06 0.36
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.064e-06 0.29
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 5.953e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 6.644e-06 0.29
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 8.562e-06 0.36
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 9.942e-06 0.29

Ozanimod

S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.445e-181 1.00
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.918e-58 1.00
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 6.982e-27 1.00
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 3.962e-19 1.00
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 2.887e-15 1.00
S1PR1_MOUSE S1pr1 Sphingosine 1-phosphate receptor 1 7.331e-33 0.39
H9EUW9_MACMU S1PR1 Sphingosine 1-phosphate receptor 1 2.886e-19 0.31
W5VNF7_CANLF S1PR1 Sphingosine-1-phosphate receptor 1 4.441e-16 0.31
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 4.623e-10 0.37
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 4.951e-08 0.28
S1PR1_RAT S1pr1 Sphingosine 1-phosphate receptor 1 7.986e-08 0.31
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 4.021e-07 0.32
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 1.024e-06 0.32

Samidorphan

OPRD_HUMAN OPRD1 Delta-type opioid receptor 9.536e-145 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.946e-132 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.588e-116 1.00
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 9.803e-162 0.69
OPRM_MOUSE Oprm1 Mu-type opioid receptor 3.051e-147 0.56
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 7.35e-123 0.50
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.444e-118 0.69
OPRD_MOUSE Oprd1 Delta-type opioid receptor 3.99e-106 0.56
OPRD_RAT Oprd1 Delta-type opioid receptor 3.685e-83 0.52
OPRM_BOVIN OPRM1 Mu-type opioid receptor 2.273e-81 0.44
OPRM_RAT Oprm1 Mu-type opioid receptor 2.361e-73 0.52
OPRK_RAT Oprk1 Kappa-type opioid receptor 7.458e-59 0.52
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.477e-56 0.36
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.41e-39 0.37
OPRX_HUMAN OPRL1 Nociceptin receptor 1.332e-15 0.42
OPRX_CAVPO OPRL1 Nociceptin receptor 2.034e-12 0.32
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 6.971e-10 0.30
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 8.161e-09 0.32

Fedratinib

TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 5.376e-68 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.138e-67 1.00
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 6.524e-44 1.00
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 2.669e-37 1.00
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 6.056e-36 1.00
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 2.191e-35 1.00
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 2.266e-35 1.00
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 7.925e-35 1.00
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 8.366e-33 1.00
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 1.735e-32 1.00
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 4.789e-32 1.00
WEE1_HUMAN WEE1 Wee1-like protein kinase 8.848e-32 1.00
YES_HUMAN YES1 Tyrosine-protein kinase Yes 2.2e-31 1.00
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 8.07e-31 1.00
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 3.937e-30 1.00
FAK1_HUMAN PTK2 Focal adhesion kinase 1 6.759e-30 1.00
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.052e-28 1.00
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 2.651e-28 1.00
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 3.59e-28 1.00
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.645e-26 1.00
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 1.645e-26 1.00
INSR_HUMAN INSR Insulin receptor 6.988e-26 1.00
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 3.449e-25 1.00
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.419e-25 1.00
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 4.419e-25 1.00
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 4.419e-25 1.00
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 4.419e-25 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 6.091e-25 1.00
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 3.656e-24 1.00
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 7.773e-24 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 5.43e-23 1.00
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 9.712e-23 1.00
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 9.712e-23 1.00
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 9.712e-23 1.00
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 9.712e-23 1.00
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 9.712e-23 1.00
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 9.712e-23 1.00
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 9.712e-23 1.00
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 9.712e-23 1.00
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 9.163e-22 1.00
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 9.163e-22 1.00
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 6.03e-21 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 6.679e-21 1.00
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 6.843e-21 1.00
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 6.843e-21 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.971e-21 1.00
AURKA_HUMAN AURKA Aurora kinase A 2.391e-20 1.00
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 3.671e-20 1.00
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 4.197e-20 1.00
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 4.197e-20 1.00
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 4.197e-20 1.00
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 9.405e-20 1.00
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.149e-19 1.00
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 1.285e-19 1.00
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.176e-19 1.00
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.176e-19 1.00
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.176e-19 1.00
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 4.891e-19 1.00
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 9.774e-19 1.00
INSRR_HUMAN INSRR Insulin receptor-related protein 9.774e-19 1.00
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 9.774e-19 1.00
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 9.774e-19 1.00
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 9.774e-19 1.00
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 2.347e-18 1.00
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 3.874e-18 1.00
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 3.874e-18 1.00
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 3.874e-18 1.00
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 3.874e-18 1.00
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 3.874e-18 1.00
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 5.28e-18 1.00
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 8.395e-18 1.00
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.377e-17 1.00
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.377e-17 1.00
BRDT_HUMAN BRDT Bromodomain testis-specific protein 1.782e-17 1.00
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1.879e-17 1.00
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 3.706e-17 1.00
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 4.449e-17 1.00
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 4.449e-17 1.00
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 4.449e-17 1.00
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 4.449e-17 1.00
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 1.11e-16 1.00
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.11e-16 1.00
FER_HUMAN FER Tyrosine-protein kinase Fer 1.11e-16 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.11e-16 1.00
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 1.11e-16 1.00
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 1.11e-16 1.00
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 1.11e-16 1.00
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.11e-16 1.00
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 1.11e-16 1.00
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 1.11e-16 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 3.331e-16 1.00
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 3.331e-16 1.00
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 3.331e-16 1.00
MET_HUMAN MET Hepatocyte growth factor receptor 3.331e-16 1.00
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 3.331e-16 1.00
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 3.331e-16 1.00
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 3.331e-16 1.00
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 3.331e-16 1.00
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 3.331e-16 1.00
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 4.441e-16 1.00
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 5.551e-16 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 5.551e-16 1.00
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 8.882e-16 1.00
DMPK_HUMAN DMPK Myotonin-protein kinase 8.882e-16 1.00
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 8.882e-16 1.00
AURKB_HUMAN AURKB Aurora kinase B 9.992e-16 1.00
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.11e-15 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 2.109e-15 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 2.109e-15 1.00
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 2.22e-15 1.00
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.22e-15 1.00
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 2.331e-15 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 2.442e-15 1.00
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 2.776e-15 1.00
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 3.997e-15 1.00
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 5.218e-15 1.00
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 5.218e-15 1.00
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 5.218e-15 1.00
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 5.44e-15 1.00
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 5.773e-15 1.00
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.033e-14 1.00
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.033e-14 1.00
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.144e-14 1.00
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1.144e-14 1.00
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.144e-14 1.00
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.144e-14 1.00
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 1.343e-14 1.00
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 1.577e-14 1.00
ACVR1_HUMAN ACVR1 Activin receptor type-1 2.01e-14 1.00
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 2.087e-14 1.00
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.121e-14 1.00
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 2.387e-14 1.00
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.387e-14 1.00
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 2.387e-14 1.00
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 3.02e-14 1.00
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 4.03e-14 1.00
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 6.04e-14 1.00
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 9.259e-14 1.00
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 9.259e-14 1.00
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 9.259e-14 1.00
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 9.259e-14 1.00
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 9.259e-14 1.00
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 9.259e-14 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.324e-13 1.00
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 1.402e-13 1.00
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 1.731e-13 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 2.121e-13 1.00
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 2.277e-13 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 2.429e-13 1.00
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 3.137e-13 1.00
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 3.137e-13 1.00
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 3.137e-13 1.00
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 3.137e-13 1.00
MINK1_HUMAN MINK1 Misshapen-like kinase 1 3.951e-13 1.00
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 4.682e-13 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 4.907e-13 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 5.316e-13 1.00
CTRO_HUMAN CIT Citron Rho-interacting kinase 5.523e-13 1.00
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 5.523e-13 1.00
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 5.523e-13 1.00
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 5.523e-13 1.00
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 5.523e-13 1.00
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 8.923e-13 1.00
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 9.46e-13 1.00
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 9.469e-13 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 9.795e-13 1.00
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 1.584e-12 1.00
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.584e-12 1.00
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.584e-12 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.885e-12 1.00
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 2.026e-12 1.00
ACV1B_HUMAN ACVR1B Activin receptor type-1B 2.589e-12 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.589e-12 1.00
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.589e-12 1.00
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 4.142e-12 1.00
E2AK1_HUMAN EIF2AK1 Eukaryotic translation initiation factor 2-alpha kinase 1 4.142e-12 1.00
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 4.142e-12 1.00
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 4.632e-12 1.00
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 6.889e-12 1.00
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 7.981e-12 1.00
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 8.066e-12 1.00
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.001e-11 1.00
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 1.001e-11 1.00
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 1.114e-11 1.00
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.201e-11 1.00
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 1.541e-11 1.00
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 2.255e-11 1.00
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 2.566e-11 1.00
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.685e-11 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 3.066e-11 1.00
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 3.307e-11 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.307e-11 1.00
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 9.605e-11 1.00
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 1.546e-10 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.839e-10 1.00
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 2.504e-10 1.00
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 2.766e-10 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 3.375e-10 1.00
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 4.504e-10 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 4.504e-10 1.00
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.958e-10 1.00
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 6.961e-10 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 7.751e-10 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1.499e-09 1.00
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 1.626e-09 1.00
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1.868e-09 1.00
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 2.136e-09 1.00
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 2.698e-09 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.749e-09 1.00
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 2.964e-09 1.00
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 3.385e-09 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 4.109e-09 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.052e-08 1.00
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1.172e-08 1.00
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 1.407e-08 1.00
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 1.568e-08 1.00
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.428e-08 1.00
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 2.882e-08 1.00
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 2.882e-08 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 3.194e-08 1.00
E2AK2_HUMAN EIF2AK2 Interferon-induced, double-stranded RNA-activated protein kinase 3.408e-08 1.00
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 3.408e-08 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.014e-08 1.00
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 4.312e-08 1.00
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 8.639e-08 1.00
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 9.552e-08 1.00
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.29e-07 1.00
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 1.318e-07 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.466e-07 1.00
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 1.539e-07 1.00
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 2.227e-07 1.00
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 2.587e-07 1.00
GAK_HUMAN GAK Cyclin-G-associated kinase 3.215e-07 1.00
AURKC_HUMAN AURKC Aurora kinase C 3.618e-07 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 5.858e-07 1.00
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 8.647e-07 1.00
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1.101e-06 1.00
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.143e-06 1.00
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.309e-06 1.00
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 2.167e-06 1.00
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 2.404e-06 1.00
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 2.871e-06 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.916e-06 1.00
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 4.883e-06 1.00
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 5.611e-06 1.00
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 6.824e-06 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.363e-05 1.00
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 1.734e-05 1.00
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 2.231e-05 1.00
LIMK1_HUMAN LIMK1 LIM domain kinase 1 2.377e-05 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 3.396e-05 1.00
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.508e-05 1.00
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 3.928e-05 1.00
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 6.503e-05 1.00
TIE2_HUMAN TEK Angiopoietin-1 receptor 0.0001354 1.00
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 0.0001966 1.00
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 0.0002494 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 0.0002589 1.00
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 0.0003744 1.00
LIMK2_HUMAN LIMK2 LIM domain kinase 2 0.0003853 1.00
NEK1_HUMAN NEK1 Serine/threonine-protein kinase Nek1 0.0005223 1.00
TTK_HUMAN TTK Dual specificity protein kinase TTK 0.0007125 1.00
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 0.0008578 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 0.001203 1.00
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 0.001381 1.00
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 0.002092 1.00
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 0.002198 1.00
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 0.002625 1.00
KPCE_HUMAN PRKCE Protein kinase C epsilon type 0.003996 1.00
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 0.004186 1.00
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 0.006458 1.00
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 0.01012 1.00
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 0.01472 1.00
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 0.0231 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 0.03238 1.00
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 0.05918 1.00
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 0.06307 1.00
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.553e-56 0.46
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 6.66e-55 0.41
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 2.984e-46 0.46
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.479e-40 0.37
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 2.271e-36 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 3.678e-36 0.40
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.449e-35 0.44
CCNH_HUMAN CCNH Cyclin-H 1.559e-35 0.37
TBK1_MOUSE Tbk1 Serine/threonine-protein kinase TBK1 2.727e-34 0.30
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 4.546e-32 0.55
SHH_MOUSE Shh Sonic hedgehog protein 3.491e-31 0.38
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 3.51e-31 0.33
ESR1_HUMAN ESR1 Estrogen receptor 5.602e-29 0.35
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.804e-28 0.36
MYT1_HUMAN MYT1 Myelin transcription factor 1 7.052e-28 0.34
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 3.315e-27 0.37
GALR2_HUMAN GALR2 Galanin receptor type 2 4.793e-27 0.32
HNMT_RAT Hnmt Histamine N-methyltransferase 1.571e-26 0.34
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 1.815e-26 0.55
ESR2_HUMAN ESR2 Estrogen receptor beta 1.207e-25 0.34
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 2.458e-23 0.55
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 2.35e-22 0.30
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 3.076e-21 0.34
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 7.378e-21 0.37
ACES_MOUSE Ache Acetylcholinesterase 1.294e-20 0.35
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 2.375e-19 0.31
CCNT1_HUMAN CCNT1 Cyclin-T1 8.433e-19 0.37
BCR_HUMAN BCR Breakpoint cluster region protein 9.052e-19 0.30
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 1.4e-18 0.55
MOGT2_HUMAN MOGAT2 2-acylglycerol O-acyltransferase 2 7.346e-18 0.30
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 9.025e-18 0.30
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 2.321e-17 0.32
GYRB_MYCSM gyrB DNA gyrase subunit B 1.11e-16 0.32
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.11e-16 0.37
Q9HUN3_PSEAE dnaB Replicative DNA helicase 2.22e-16 0.36
CGAS_HUMAN CGAS Cyclic GMP-AMP synthase 9.992e-16 0.30
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.443e-15 0.34
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.554e-15 0.38
HRH3_RAT Hrh3 Histamine H3 receptor 1.776e-15 0.35
CCNA1_HUMAN CCNA1 Cyclin-A1 2.776e-15 0.37
KPCT_HUMAN PRKCQ Protein kinase C theta type 8.771e-15 0.39
CCNA2_HUMAN CCNA2 Cyclin-A2 2.442e-14 0.37
ESR1_RAT Esr1 Estrogen receptor 1.255e-12 0.33
NORA_STAAU norA Quinolone resistance protein NorA 1.257e-12 0.33
CHLE_HORSE BCHE Cholinesterase 1.516e-12 0.34
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 1.58e-12 0.55
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.288e-12 0.55
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 4.154e-12 0.32
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 4.7e-12 0.40
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 5.654e-12 0.44
HRH3_MOUSE Hrh3 Histamine H3 receptor 6.117e-12 0.32
ACES_ELEEL ache Acetylcholinesterase 7.338e-12 0.34
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 1.599e-11 0.55
MK12_HUMAN MAPK12 Mitogen-activated protein kinase 12 2.86e-11 0.55
KPCG_HUMAN PRKCG Protein kinase C gamma type 3.226e-11 0.55
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 3.701e-11 0.55
GALR1_HUMAN GALR1 Galanin receptor type 1 4.546e-11 0.32
RON_HUMAN MST1R Macrophage-stimulating protein receptor 5.358e-11 0.39
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 1.201e-10 0.55
HRH2_CAVPO HRH2 Histamine H2 receptor 1.559e-10 0.31
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 1.903e-10 0.55
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 2.198e-10 0.55
HRH2_HUMAN HRH2 Histamine H2 receptor 3.225e-10 0.33
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 3.325e-10 0.55
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 4.908e-10 0.55
DUT_HUMAN DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 7.181e-10 0.30
PIR_HUMAN PIR Pirin 7.541e-10 0.29
HSF1_HUMAN HSF1 Heat shock factor protein 1 8.439e-10 0.31
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 2.168e-09 0.55
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 3.431e-09 0.44
O97467_PLAFA ht1 Hexose transporter 1 4.252e-09 0.46
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 6.436e-09 0.32
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 6.816e-09 0.38
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 6.953e-09 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 7.189e-09 0.35
V1BR_RAT Avpr1b Vasopressin V1b receptor 8.793e-09 0.30
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 8.894e-09 0.35
DPO3_STAAU polC DNA polymerase III PolC-type 1.791e-08 0.28
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 2.902e-08 0.35
HRH1_HUMAN HRH1 Histamine H1 receptor 3.398e-08 0.33
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 3.488e-08 0.55
TERT_HUMAN TERT Telomerase reverse transcriptase 4.848e-08 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.688e-08 0.33
KPCD_HUMAN PRKCD Protein kinase C delta type 6.622e-08 0.55
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 7.755e-08 0.44
Q63380_RAT NET Transporter 7.983e-08 0.34
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.199e-07 0.46
ESR2_RAT Esr2 Estrogen receptor beta 1.23e-07 0.33
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.231e-07 0.55
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.025e-07 0.31
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 2.157e-07 0.44
TLR9_HUMAN TLR9 Toll-like receptor 9 2.34e-07 0.30
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 3.748e-07 0.33
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 3.876e-07 0.55
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 3.983e-07 0.29
Q865E1_MACMU HRH3 Histamine receptor H3 4.026e-07 0.35
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 4.976e-07 0.30
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 5.12e-07 0.31
O61059_LEIME LmGT2 Glucose transporter 5.458e-07 0.31
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 5.516e-07 0.32
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 5.865e-07 0.30
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.201e-06 0.35
MK13_HUMAN MAPK13 Mitogen-activated protein kinase 13 3.029e-06 0.44
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 4.553e-06 0.36
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 4.599e-06 0.44
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 4.682e-06 0.35
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 8.339e-06 0.30

Givinostat

HDAC8_HUMAN HDAC8 Histone deacetylase 8 9.554e-37 1.00
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.48e-35 1.00
HDAC1_HUMAN HDAC1 Histone deacetylase 1 3.292e-28 1.00
HDAC7_HUMAN HDAC7 Histone deacetylase 7 4.411e-18 1.00
HDAC9_HUMAN HDAC9 Histone deacetylase 9 1.11e-16 1.00
HDAC5_HUMAN HDAC5 Histone deacetylase 5 3.764e-14 1.00
HDAC2_HUMAN HDAC2 Histone deacetylase 2 4.567e-13 1.00
Q9ZTP8_MAIZE hd1b Histone deacetylase 1.839e-10 1.00
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.961e-08 1.00
HDAC4_HUMAN HDAC4 Histone deacetylase 4 2.387e-06 1.00
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.966e-70 0.36
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 4.597e-56 0.33
O68720_YERPE yopH Targeted effector protein 7.84e-56 0.33
UROK_RAT Plau Urokinase-type plasminogen activator 2.938e-47 0.30
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 6.899e-45 0.33
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.14e-41 0.33
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.081e-37 0.36
ECR_CHITE EcR Ecdysone receptor 1.627e-37 0.30
ECR_HELVI EcR Ecdysone receptor 1.627e-37 0.30
O45117_CHITE USP-1 Ultraspiracle 1.627e-37 0.30
Q6IVK1_PLOIN USP 1.627e-37 0.30
Q6RVD3_PLOIN Ecdysone receptor 1.627e-37 0.30
Q7SIF6_HELVI Gene regulation protein 1.627e-37 0.30
Q8I1M8_CHISP CsUSP Ultraspiracle 1.627e-37 0.30
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 1.627e-37 0.30
Q962I5_LUCCU Ultraspiracle protein 1.627e-37 0.30
USP_CHOFU USP Protein ultraspiracle homolog 1.627e-37 0.30
THRB_MOUSE F2 Prothrombin 2.223e-37 0.30
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 1.948e-36 0.29
KLK2_HUMAN KLK2 Kallikrein-2 2.317e-35 0.32
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.366e-35 0.41
KLK8_HUMAN KLK8 Kallikrein-8 4.847e-32 0.32
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 7.669e-31 0.36
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 5.719e-30 0.34
KLK4_HUMAN KLK4 Kallikrein-4 2.017e-29 0.32
ACRO_HUMAN ACR Acrosin 4.935e-28 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 1.195e-27 0.37
UROK_MOUSE Plau Urokinase-type plasminogen activator 2.6e-26 0.30
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 2.945e-26 0.30
PLMN_MOUSE Plg Plasminogen 4.628e-24 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 6.312e-23 0.31
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 4.621e-21 0.36
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.442e-20 0.29
GIPR_RAT Gipr Gastric inhibitory polypeptide receptor 2.036e-19 0.31
PRIO_SHEEP PRNP Major prion protein 3.386e-19 0.37
TSHB_BOVIN TSHB Thyrotropin subunit beta 5.705e-19 0.30
Q4W6C8_LEPDE LdUSP Ultraspiracle 1.039e-18 0.30
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 1.039e-18 0.30
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 3.615e-18 0.29
Q9GSG8_AEDAE Ultraspiracle isoform-A 1.221e-15 0.30
PLMN_HUMAN PLG Plasminogen 1.887e-15 0.41
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.997e-15 0.39
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 6.106e-15 0.33
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.143e-14 0.34
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.625e-13 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.625e-13 0.30
GLR_HUMAN GCGR Glucagon receptor 3e-13 0.34
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 4.131e-13 0.29
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.664e-12 0.33
TRY1_HUMAN PRSS1 Trypsin-1 2.531e-11 0.41
LYOX_HUMAN LOX Protein-lysine 6-oxidase 4.65e-11 0.29
E3UJZ5_SPOLI Ecdysone receptor 5.773e-11 0.30
RS27_HUMAN RPS27 40S ribosomal protein S27 1.522e-10 0.28
UT1_RAT Slc14a1 Urea transporter 1 1.647e-10 0.28
USP_DROME usp Protein ultraspiracle 3.004e-10 0.30
HDA11_HUMAN HDAC11 Histone deacetylase 11 4.635e-10 0.40
RCOR1_HUMAN RCOR1 REST corepressor 1 1.061e-09 0.34
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.148e-09 0.39
ECR_LUCCU EcR Ecdysone receptor 1.692e-09 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.029e-09 0.39
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.996e-09 0.29
GLR_RAT Gcgr Glucagon receptor 6.205e-09 0.31
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 6.485e-09 0.29
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.071e-08 0.33
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 1.192e-08 0.29
MEP1B_HUMAN MEP1B Meprin A subunit beta 1.6e-08 0.29
NOX1_HUMAN NOX1 NADPH oxidase 1 1.688e-08 0.31
ECR_DROME EcR Ecdysone receptor 1.804e-08 0.30
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.476e-08 0.40
ANDR_MOUSE Ar Androgen receptor 1.151e-07 0.33
KLK1_HUMAN KLK1 Kallikrein-1 1.404e-07 0.32
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.744e-07 0.33
ECR_BOMMO EcR Ecdysone receptor 1.783e-07 0.30
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.789e-07 0.34
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 1.921e-07 0.32
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.196e-07 0.30
POLG_DEN2P Genome polyprotein 4.405e-07 0.30
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 4.685e-07 0.43
O77240_CHOFU EcR Ecdysone receptor isoform A 1.003e-06 0.30
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.14e-06 0.29
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.206e-06 0.37
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.033e-06 0.29
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.808e-06 0.40
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.849e-06 0.29
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.384e-06 0.34
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.789e-06 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.983e-06 0.31
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 8.538e-06 0.32

Sparsentan

EDNRA_HUMAN EDNRA Endothelin-1 receptor 4.339e-35 1.00
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 1.882e-22 1.00
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 3.046e-59 0.64
EDNRB_RAT Ednrb Endothelin receptor type B 1.3e-21 0.39
EDNRB_HUMAN EDNRB Endothelin receptor type B 4.431e-17 0.45
EDNRA_RAT Ednra Endothelin-1 receptor 1.11e-16 0.39
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 2.109e-15 0.30
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 2.104e-12 0.34
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 4.591e-11 0.31
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.656e-07 0.51
MTLR_HUMAN MLNR Motilin receptor 4.27e-06 0.29
ACES_RAT Ache Acetylcholinesterase 5.024e-06 0.47

Mizolastine

HRH1_HUMAN HRH1 Histamine H1 receptor 7.585e-34 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.537e-11 1.00
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 1.7e-131 0.38
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 5.274e-102 0.42
HMOX2_RAT Hmox2 Heme oxygenase 2 6.801e-38 0.43
SOS1_HUMAN SOS1 Son of sevenless homolog 1 2.162e-24 0.39
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 1.342e-23 0.35
HRH1_CAVPO HRH1 Histamine H1 receptor 2.783e-23 0.47
CRY2_HUMAN CRY2 Cryptochrome-2 4.035e-23 0.28
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 6.198e-22 0.49
MTLR_HUMAN MLNR Motilin receptor 2.127e-21 0.32
MURI_ENTFA murI Glutamate racemase 4.758e-19 0.30
DRD2_MOUSE Drd2 D(2) dopamine receptor 5.974e-19 0.31
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 1.085e-18 0.28
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 3.379e-17 0.31
NK1R_CAVPO TACR1 Substance-P receptor 3.331e-16 0.40
Q581W1_TRYB2 Pteridine reductase, putative 3.963e-14 0.31
RGS4_HUMAN RGS4 Regulator of G-protein signaling 4 5.129e-14 0.30
Q7ZJM1_9HIV1 pol Integrase 1.004e-12 0.30
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 1.143e-11 0.32
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 1.342e-11 0.35
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.928e-11 0.37
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 2.671e-11 0.40
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 2.91e-11 0.35
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 2.92e-11 0.31
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 3.449e-11 0.33
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 5.14e-11 0.37
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 5.476e-11 0.34
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 7.662e-11 0.43
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 8.4e-11 0.32
CALM_BOVIN CALM Calmodulin 9.695e-11 0.29
HRH3_HUMAN HRH3 Histamine H3 receptor 2.002e-10 0.43
GRM2_HUMAN GRM2 Metabotropic glutamate receptor 2 2.398e-10 0.35
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 6.515e-10 0.34
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 7.541e-10 0.29
Q76353_9HIV1 Integrase 7.664e-10 0.32
CCR1_MOUSE Ccr1 C-C chemokine receptor type 1 2.087e-09 0.30
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 2.801e-09 0.33
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.189e-09 0.29
RGS8_HUMAN RGS8 Regulator of G-protein signaling 8 7.778e-09 0.29
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 8.705e-09 0.32
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.129e-08 0.67
E1BN64_BOVIN PDE3B Phosphodiesterase 1.634e-08 0.28
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.702e-08 0.38
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 4.721e-08 0.35
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 6.563e-08 0.44
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 8.541e-08 0.41
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 1.272e-07 0.34
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.473e-07 0.29
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 2.131e-07 0.41
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 4.12e-07 0.29
Q8MMZ8_EIMTE cGMP-dependent protein kinase 5.423e-07 0.30
PER2_HUMAN PER2 Period circadian protein homolog 2 5.535e-07 0.30
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 6.151e-07 0.41
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 6.221e-07 0.59
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 6.39e-07 0.28
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 6.671e-07 0.32
CENPE_HUMAN CENPE Centromere-associated protein E 7.383e-07 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.535e-06 0.49
PLD1_RAT Pld1 Phospholipase D1 4.586e-06 0.30
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 5.752e-06 0.28
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 6.059e-06 0.33
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 6.444e-06 0.35
H4_HUMAN H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4-16 Histone H4 6.545e-06 0.34
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 8.88e-06 0.30

Copanlisib

PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5.573e-21 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.0001119 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0.002681 1.00
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 0.008401 1.00
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.319e-56 0.34
HGF_HUMAN HGF Hepatocyte growth factor 3.098e-40 0.31
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 7.806e-37 0.35
SCRB1_HUMAN SCARB1 Scavenger receptor class B member 1 4.953e-28 0.37
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.145e-27 0.31
AUKBA_XENLA aurkb-a Aurora kinase B-A 8.731e-25 0.40
IMA1_HUMAN KPNA2 Importin subunit alpha-1 4.633e-23 0.28
RENI_CALJA REN Renin 1.307e-21 0.37
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.095e-20 0.36
PIR_HUMAN PIR Pirin 4.906e-20 0.32
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 1.61e-19 0.35
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.11e-16 0.35
SRC_RAT Src Proto-oncogene tyrosine-protein kinase Src 3.331e-16 0.30
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 8.882e-16 0.34
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 8.882e-16 0.34
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 8.882e-16 0.34
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.776e-15 0.34
MET_HUMAN MET Hepatocyte growth factor receptor 2.331e-15 0.40
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 4.219e-15 0.40
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.242e-14 0.34
ALBU_HUMAN ALB Serum albumin 4.141e-14 0.32
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 7.838e-14 0.34
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1.202e-13 0.56
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.242e-13 0.34
CTRO_HUMAN CIT Citron Rho-interacting kinase 7.285e-13 0.34
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 7.285e-13 0.34
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.008e-13 0.34
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.068e-12 0.34
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.068e-12 0.34
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 3.364e-12 0.34
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 7.806e-12 0.36
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 1.456e-11 0.34
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.581e-11 0.40
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 1.597e-11 0.31
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.387e-11 0.34
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 3.187e-11 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 4.532e-11 0.40
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 4.858e-11 0.34
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 5.119e-11 0.34
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 9.305e-11 0.34
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 1.114e-10 0.34
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.285e-10 0.34
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.966e-10 0.34
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 3.52e-10 0.31
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 4.185e-10 0.34
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 4.192e-10 0.34
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 4.192e-10 0.34
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 5.359e-10 0.34
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 5.557e-10 0.34
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 6.27e-10 0.35
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 7.348e-10 0.34
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 8.934e-10 0.34
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 8.95e-10 0.34
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.615e-09 0.34
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 1.815e-09 0.31
AURKA_HUMAN AURKA Aurora kinase A 2.78e-09 0.41
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 3.513e-09 0.34
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 4.77e-09 0.34
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.988e-09 0.34
MYO3A_HUMAN MYO3A Myosin-IIIa 4.988e-09 0.34
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 7.804e-09 0.34
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 9.88e-09 0.36
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.334e-08 0.34
MYO3B_HUMAN MYO3B Myosin-IIIb 1.334e-08 0.34
RON_HUMAN MST1R Macrophage-stimulating protein receptor 2.177e-08 0.34
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.749e-08 0.33
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.89e-08 0.34
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 4.045e-08 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 4.225e-08 0.34
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.756e-08 0.34
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 6.858e-08 0.34
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 7.528e-08 0.34
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 7.864e-08 0.34
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 9.871e-08 0.38
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.369e-07 0.34
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.369e-07 0.34
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.485e-07 0.34
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 2.536e-07 0.40
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 2.551e-07 0.34
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 2.554e-07 0.34
HRH3_RAT Hrh3 Histamine H3 receptor 2.87e-07 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.822e-07 0.40
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 4.501e-07 0.34
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 4.931e-07 0.34
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 7.045e-07 0.29
INSRR_HUMAN INSRR Insulin receptor-related protein 7.551e-07 0.34
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 7.551e-07 0.34
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 7.551e-07 0.34
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.214e-06 0.34
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.214e-06 0.34
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 1.214e-06 0.34
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 1.295e-06 0.34
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 1.612e-06 0.34
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.847e-06 0.34
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.88e-06 0.34
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.88e-06 0.34
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.884e-06 0.34
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.112e-06 0.39
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 2.229e-06 0.34
PDE6A_HUMAN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 2.244e-06 0.29
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.818e-06 0.34
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 4.104e-06 0.34
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 4.104e-06 0.34
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 4.104e-06 0.34
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 4.425e-06 0.34
DRD1_MOUSE Drd1 D(1A) dopamine receptor 5.429e-06 0.31
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 5.658e-06 0.56
HDAC2_HUMAN HDAC2 Histone deacetylase 2 5.785e-06 0.35
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.825e-06 0.34
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 5.825e-06 0.34
LCK_HUMAN LCK Tyrosine-protein kinase Lck 6.229e-06 0.40
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.436e-06 0.33
NK2R_MOUSE Tacr2 Substance-K receptor 6.733e-06 0.29
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 7.719e-06 0.34
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 7.877e-06 0.33
DMPK_HUMAN DMPK Myotonin-protein kinase 7.908e-06 0.34
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 8.239e-06 0.30
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8.364e-06 0.29
KMO_HUMAN KMO Kynurenine 3-monooxygenase 8.68e-06 0.31

Clascoterone

ANDR_HUMAN AR Androgen receptor 4.081e-12 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 6.975e-108 0.67
Q690N0_BOVIN PGR Progesterone receptor 5.295e-92 0.58
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.426e-80 0.46
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.402e-74 0.67
CP19A_HUMAN CYP19A1 Aromatase 1.388e-70 0.49
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 4.164e-59 0.54
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.735e-49 0.46
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1e-41 0.36
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.043e-38 0.49
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 4.082e-36 0.30
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.855e-34 0.54
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.378e-33 0.59
ANDR_RAT Ar Androgen receptor 6.417e-32 0.59
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.47e-29 0.53
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 5.44e-29 0.47
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.758e-26 0.49
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.649e-26 0.42
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.348e-23 0.29
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 5.289e-23 0.31
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.121e-21 0.39
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.434e-21 0.46
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.861e-20 0.58
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.445e-18 0.49
ANDR_MOUSE Ar Androgen receptor 1.11e-16 0.59
PRGR_RABIT PGR Progesterone receptor 1.11e-15 0.49
PRGR_RAT Pgr Progesterone receptor 2.22e-15 0.34
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.499e-13 0.49
ERG2_YEAST ERG2 C-8 sterol isomerase 1.483e-12 0.49
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.862e-12 0.53
GLNA_HUMAN GLUL Glutamine synthetase 4.838e-12 0.38
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.517e-11 0.30
GCR_RAT Nr3c1 Glucocorticoid receptor 2.222e-11 0.38
IL6_HUMAN IL6 Interleukin-6 1.304e-09 0.38
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 5.427e-09 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.814e-08 0.59
PRGR_HUMAN PGR Progesterone receptor 5.541e-07 0.49
MCR_RAT Nr3c2 Mineralocorticoid receptor 9.927e-07 0.41
CP19A_RAT Cyp19a1 Aromatase 1.027e-06 0.46

Protionamide

PPO2_AGABI PPO2 Polyphenol oxidase 2 3.175e-08 1.00
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 1.789e-100 0.40
KDM6A_HUMAN KDM6A Lysine-specific demethylase 6A 6.992e-50 0.32
HIF1N_HUMAN HIF1AN Hypoxia-inducible factor 1-alpha inhibitor 1.097e-35 0.28
Q44079_AERHY cphA2 Beta-lactamase 5.518e-23 0.28
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 1.015e-19 0.39
LOXL2_RAT Loxl2 Lysyl oxidase homolog 2 8.104e-18 0.28
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 2.533e-17 0.33
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 1.665e-15 0.40
LOXL2_MOUSE Loxl2 Lysyl oxidase homolog 2 6.772e-15 0.28
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 6.465e-13 0.30
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 9.7e-12 0.29
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.339e-11 0.28
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.495e-11 0.31
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 1.874e-10 0.40
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.87e-09 0.32
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 5.625e-09 0.33
LOXL3_HUMAN LOXL3 Lysyl oxidase homolog 3 4.951e-08 0.28
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 1.041e-07 0.33
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 1.833e-07 0.40
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 3.681e-07 0.40
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 1.092e-06 0.28
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 7.099e-06 0.29
LYOX_HUMAN LOX Protein-lysine 6-oxidase 8.279e-06 0.28

Mebeverine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0009449 1.00
RENI_CALJA REN Renin 1.46e-115 0.34
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 6.794e-75 0.37
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.083e-71 0.42
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 4.111e-61 0.36
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 3.953e-45 0.39
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 4.149e-45 0.32
TLR1_HUMAN TLR1 Toll-like receptor 1 5.965e-45 0.36
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 3.85e-40 0.36
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.727e-37 0.38
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.727e-37 0.38
GLUT4_RAT Slc2a4 Solute carrier family 2, facilitated glucose transporter member 4 8.297e-37 0.29
GTR8_HUMAN SLC2A8 Solute carrier family 2, facilitated glucose transporter member 8 8.297e-37 0.29
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.974e-36 0.30
Q7M3D2_RABIT Renin 6.145e-36 0.28
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 1.609e-35 0.28
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.33e-35 0.36
RENI_HUMAN REN Renin 2.326e-32 0.37
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 3.629e-30 0.30
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 3.016e-29 0.44
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 7.029e-27 0.38
CAC1C_MOUSE Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.656e-24 0.30
CATZ_RAT Ctsz Cathepsin Z 1.069e-23 0.29
CXL10_HUMAN CXCL10 C-X-C motif chemokine 10 2.586e-23 0.32
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 2.614e-21 0.30
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.567e-20 0.31
NADE_BACSU nadE NH(3)-dependent NAD(+) synthetase 6.33e-20 0.32
ACRO_PIG ACR Acrosin 9.668e-20 0.34
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 6.432e-19 0.33
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 6.432e-19 0.33
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 6.432e-19 0.33
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 6.432e-19 0.33
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 6.432e-19 0.33
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 6.432e-19 0.33
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 6.432e-19 0.33
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 6.432e-19 0.33
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 6.432e-19 0.33
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 6.432e-19 0.33
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 6.432e-19 0.33
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 6.432e-19 0.33
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 6.432e-19 0.33
AUR1_CANAL AUR1 Inositol phosphorylceramide synthase 9.376e-19 0.30
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 9.911e-19 0.34
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 9.937e-19 0.33
KLK14_HUMAN KLK14 Kallikrein-14 1.039e-18 0.30
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.258e-18 0.33
CATH_RAT Ctsh Pro-cathepsin H 2.301e-18 0.29
CATJ_RAT Ctsj Cathepsin J 2.301e-18 0.29
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 2.56e-18 0.33
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.004e-18 0.34
PDE2A_RAT Pde2a cGMP-dependent 3',5'-cyclic phosphodiesterase 4.879e-18 0.29
RENI_MACMU REN Renin 6.109e-18 0.28
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 7.082e-18 0.35
O30463_MYCAV folA Dihydrofolate reductase 8.433e-18 0.32
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.656e-17 0.32
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.216e-17 0.32
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.573e-17 0.32
ACRO_HUMAN ACR Acrosin 1.11e-16 0.34
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 1.11e-16 0.33
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.11e-16 0.35
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.11e-15 0.32
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 1.554e-15 0.33
CATC_RAT Ctsc Dipeptidyl peptidase 1 2.442e-15 0.29
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 2.665e-15 0.37
CBX8_HUMAN CBX8 Chromobox protein homolog 8 3.331e-15 0.33
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.553e-15 0.33
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 5.662e-15 0.35
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 1.288e-14 0.33
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.701e-13 0.36
ACES_HUMAN ACHE Acetylcholinesterase 3.025e-13 0.39
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.142e-13 0.33
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 4.442e-13 0.38
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 5.987e-13 0.33
CBX7_HUMAN CBX7 Chromobox protein homolog 7 9.68e-13 0.33
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.017e-12 0.36
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.113e-12 0.38
KLK5_HUMAN KLK5 Kallikrein-5 1.16e-12 0.32
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 1.434e-12 0.33
THA_HUMAN THRA Thyroid hormone receptor alpha 1.759e-12 0.38
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.761e-12 0.37
O90781_9PLVG HIV-1 protease HIV-1 protease 1.828e-12 0.31
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 4.959e-12 0.29
Q53I59_TRYCR PDEC Phosphodiesterase 6.833e-12 0.29
ACES_RAT Ache Acetylcholinesterase 7.144e-12 0.37
ERG1_RAT Sqle Squalene monooxygenase 9.49e-12 0.31
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.492e-11 0.30
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 1.579e-11 0.37
Q8Z9J9_SALTI folA Dihydrofolate reductase 3.052e-11 0.31
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.414e-11 0.32
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 4.724e-11 0.29
A5H660_SCHMA HDAC8 Histone deacetylase 8 6.921e-11 0.31
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.233e-10 0.37
RENI1_MOUSE Ren1 Renin-1 1.257e-10 0.28
CYSP_PLAFA Trophozoite cysteine proteinase 1.292e-10 0.31
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.577e-10 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.746e-10 0.38
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.765e-10 0.31
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 2.437e-10 0.33
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 2.464e-10 0.40
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.94e-10 0.32
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 3.224e-10 0.46
DYR_PNECA Dihydrofolate reductase 3.429e-10 0.40
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 3.77e-10 0.38
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 5.366e-10 0.41
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 6.25e-10 0.32
EST1_RABIT Liver carboxylesterase 1 7.247e-10 0.31
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 7.4e-10 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7.578e-10 0.31
TRY1_HUMAN PRSS1 Trypsin-1 8.067e-10 0.39
S100B_HUMAN S100B Protein S100-B 1.087e-09 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.248e-09 0.31
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.992e-09 0.30
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.338e-09 0.32
EDNRA_RAT Ednra Endothelin-1 receptor 3.162e-09 0.32
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 4.037e-09 0.32
NORA_STAAU norA Quinolone resistance protein NorA 4.111e-09 0.30
ENTK_HUMAN TMPRSS15 Enteropeptidase 4.882e-09 0.30
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 5.048e-09 0.28
THB_HUMAN THRB Thyroid hormone receptor beta 6.788e-09 0.38
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 8.655e-09 0.31
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.002e-08 0.33
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.137e-08 0.33
Q49PX0_9POXV N1L N1L 1.264e-08 0.31
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.309e-08 0.32
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.63e-08 0.42
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.864e-08 0.29
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 1.912e-08 0.30
THAS_HUMAN TBXAS1 Thromboxane-A synthase 2.228e-08 0.38
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.552e-08 0.33
LRP6_HUMAN LRP6 Low-density lipoprotein receptor-related protein 6 3.836e-08 0.30
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 4.633e-08 0.30
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 4.633e-08 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 7.492e-08 0.32
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 7.6e-08 0.35
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 8.425e-08 0.32
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 9.521e-08 0.29
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 9.586e-08 0.35
FA12_HUMAN F12 Coagulation factor XII 1.01e-07 0.32
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.119e-07 0.31
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.209e-07 0.29
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.404e-07 0.33
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.436e-07 0.30
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.721e-07 0.29
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 2.148e-07 0.29
DYR_RAT Dhfr Dihydrofolate reductase 2.541e-07 0.40
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 2.738e-07 0.34
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 3.173e-07 0.38
CHLE_HUMAN BCHE Cholinesterase 3.26e-07 0.35
LSS_HUMAN LSS Lanosterol synthase 3.403e-07 0.32
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.617e-07 0.35
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 3.665e-07 0.31
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 3.917e-07 0.30
ACES_ELEEL ache Acetylcholinesterase 4.017e-07 0.33
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 4.302e-07 0.41
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 4.905e-07 0.29
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 5.093e-07 0.36
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 5.216e-07 0.30
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 6.033e-07 0.29
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.257e-07 0.33
TSPO_RAT Tspo Translocator protein 8.243e-07 0.33
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 9.298e-07 0.30
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 9.387e-07 0.32
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.013e-06 0.36
CHLE_HORSE BCHE Cholinesterase 1.262e-06 0.33
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 1.304e-06 0.34
POLG_HCV77 Genome polyprotein 1.427e-06 0.31
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 1.574e-06 0.33
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.597e-06 0.30
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.815e-06 0.28
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.815e-06 0.28
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.815e-06 0.28
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.815e-06 0.28
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.815e-06 0.28
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.815e-06 0.28
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.815e-06 0.28
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.815e-06 0.28
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.815e-06 0.28
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.815e-06 0.28
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.815e-06 0.28
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.815e-06 0.28
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.815e-06 0.28
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.815e-06 0.28
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.815e-06 0.28
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.815e-06 0.28
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.815e-06 0.28
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.815e-06 0.28
AOC3_HUMAN AOC3 Membrane primary amine oxidase 2.074e-06 0.33
EDNRB_PIG EDNRB Endothelin receptor type B 2.455e-06 0.30
ITB3_HUMAN ITGB3 Integrin beta-3 3.557e-06 0.38
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.563e-06 0.28
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.772e-06 0.39
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 4.342e-06 0.32
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 4.652e-06 0.37
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 4.69e-06 0.33
KLK7_HUMAN KLK7 Kallikrein-7 5.855e-06 0.32
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.755e-06 0.29
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 7.77e-06 0.28
Q9S446_STAAU srtA Class A sortase SrtA 8.152e-06 0.29

Oxethazaine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.002512 1.00
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 3.758e-129 0.40
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 8.293e-47 0.35
DXS_HAEI8 dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.102e-45 0.29
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 5.386e-39 0.34
Q8ILP4_PLAF7 Pantothenate kinase, putative 1.948e-36 0.29
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.151e-27 0.33
Q704V1_PSEAI blaGIM-1 GIM-1 protein 4.633e-23 0.28
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.177e-14 0.34
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1.688e-14 0.39
Q8WMX0_BOVIN Muscarinic receptor M1 1.734e-13 0.33
ISPA_ECOLI ispA Farnesyl diphosphate synthase 2.343e-13 0.29
USP_DROME usp Protein ultraspiracle 3.398e-10 0.30
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.108e-09 0.31
ECR_DROME EcR Ecdysone receptor 1.995e-08 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.663e-08 0.35
NK3R_CAVPO TACR3 Neuromedin-K receptor 6.051e-08 0.28
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.195e-07 0.32
ECR_BOMMO EcR Ecdysone receptor 1.722e-07 0.30
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 2.047e-07 0.31
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 3.065e-07 0.31
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 7.045e-07 0.29
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 8.033e-07 0.36
GP119_MOUSE Gpr119 Glucose-dependent insulinotropic receptor 1.361e-06 0.31
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.776e-06 0.29
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.201e-06 0.33
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.482e-06 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.03e-06 0.33
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 3.213e-06 0.28
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 3.463e-06 0.32
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.484e-06 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 3.91e-06 0.31
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 6.296e-06 0.34

Perazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.202e-159 0.80
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.967e-85 0.47
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 4.286e-75 0.80
EBPL_HUMAN EBPL Emopamil-binding protein-like 1.696e-61 0.73
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 8.023e-59 0.32
PRIO_MOUSE Prnp Major prion protein 1.225e-58 0.47
LYSC1_RAT Lyz1 Lysozyme C-1 6.659e-58 0.73
TYTR_TRYCR TPR Trypanothione reductase 5.191e-57 0.47
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.979e-54 0.41
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.366e-52 0.62
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 4.039e-50 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.06e-49 0.80
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 3.25e-47 0.47
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.775e-45 0.80
BGLR_RAT Gusb Beta-glucuronidase 1.317e-44 0.73
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 4.034e-44 0.35
DRD2_RAT Drd2 D(2) dopamine receptor 1.925e-43 0.73
CALM_BOVIN CALM Calmodulin 3.84e-42 0.73
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.287e-40 0.57
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 1.782e-39 0.35
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 2.358e-39 0.39
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.209e-34 0.80
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.543e-33 0.80
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.534e-32 0.80
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.742e-32 0.35
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.499e-31 0.33
CALM1_HUMAN CALM1 Calmodulin-1 1.542e-31 0.73
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 8.192e-29 0.80
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 5.885e-28 0.34
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.839e-26 0.42
HRH1_HUMAN HRH1 Histamine H1 receptor 2.044e-26 0.80
DRD1_PIG DRD1 D(1A) dopamine receptor 3.415e-26 0.34
DRD5_HUMAN DRD5 D(1B) dopamine receptor 3.547e-26 0.57
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.589e-26 0.80
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.613e-25 0.80
DRD1_RAT Drd1 D(1A) dopamine receptor 3.121e-25 0.47
DRD3_RAT Drd3 D(3) dopamine receptor 9.318e-25 0.38
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 4.83e-24 0.33
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.019e-24 0.80
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.565e-23 0.39
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 2.075e-23 0.80
ITAM_HUMAN ITGAM Integrin alpha-M 4.377e-23 0.28
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.236e-22 0.42
DRD4_RAT Drd4 D(4) dopamine receptor 4.761e-22 0.36
CHLE_HUMAN BCHE Cholinesterase 4.989e-22 0.42
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.052e-21 0.80
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 6.4e-21 0.36
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.996e-21 0.80
HRH3_CAVPO HRH3 Histamine H3 receptor 1.198e-20 0.33
Q39829_SOYBN Lipoxygenase 1.475e-20 0.33
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.376e-19 0.73
ERG2_YEAST ERG2 C-8 sterol isomerase 4.518e-19 0.73
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 6.379e-19 0.80
HRH1_RAT Hrh1 Histamine H1 receptor 3.582e-18 0.56
NOX1_HUMAN NOX1 NADPH oxidase 1 1.232e-17 0.37
Q9IP65_HCMV US28 G protein-coupled receptor 1.882e-17 0.33
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.11e-16 0.80
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.11e-16 0.33
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.11e-16 0.42
CHLE_HORSE BCHE Cholinesterase 3.331e-16 0.56
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.11e-15 0.30
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 2.665e-15 0.29
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 3.109e-15 0.33
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.132e-14 0.32
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.598e-14 0.80
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 3.73e-14 0.39
HRH2_HUMAN HRH2 Histamine H2 receptor 1.383e-13 0.57
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 8.7e-13 0.80
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.091e-12 0.80
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.381e-12 0.80
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 2.064e-12 0.30
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 2.182e-12 0.40
US28_HCMVA US28 G-protein coupled receptor homolog US28 2.492e-12 0.33
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 2.853e-12 0.41
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.212e-12 0.47
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.496e-12 0.80
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 5.771e-12 0.38
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 9.761e-12 0.80
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.375e-11 0.80
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 2.335e-11 0.33
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.333e-11 0.32
HNMT_RAT Hnmt Histamine N-methyltransferase 3.378e-11 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 8.938e-11 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.239e-10 0.42
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 2.912e-10 0.39
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.358e-10 0.80
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 5.162e-10 0.29
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 5.204e-10 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.124e-09 0.39
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.24e-09 0.47
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.836e-09 0.33
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.609e-09 0.37
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 3.791e-09 0.80
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.834e-09 0.38
ACES_ELEEL ache Acetylcholinesterase 5.723e-09 0.39
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 8.14e-09 0.39
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.006e-08 0.80
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 1.097e-08 0.36
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.29e-08 0.47
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.579e-08 0.39
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.751e-08 0.28
WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.779e-08 0.73
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 2.5e-08 0.73
CHKA_HUMAN CHKA Choline kinase alpha 3.591e-08 0.34
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 3.895e-08 0.35
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 4.199e-08 0.41
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 4.37e-08 0.29
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 6.618e-08 0.33
DEF_STAAM def Peptide deformylase 6.648e-08 0.32
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 7.276e-08 0.41
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.847e-08 0.31
TYTR_TRYBB TPR Trypanothione reductase 1.246e-07 0.35
PRIO_HUMAN PRNP Major prion protein 2e-07 0.56
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.231e-07 0.33
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 6.696e-07 0.33
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 7.234e-07 0.52
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 7.428e-07 0.33
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.829e-07 0.30
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.311e-06 0.31
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.473e-06 0.80
ACHP_LYMST Acetylcholine-binding protein 1.586e-06 0.36
O97467_PLAFA ht1 Hexose transporter 1 1.766e-06 0.31
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.854e-06 0.32
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 2.284e-06 0.36
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 4.526e-06 0.44
MC4R_HUMAN MC4R Melanocortin receptor 4 4.602e-06 0.41
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 7.172e-06 0.80
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 8.994e-06 0.29
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 9.868e-06 0.30

Pentetreotide

CD36_RAT Cd36 Platelet glycoprotein 4 3.332e-116 0.37
SSR5_RAT Sstr5 Somatostatin receptor type 5 8.995e-114 0.69
MC5R_MOUSE Mc5r Melanocortin receptor 5 2.027e-113 0.35
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 9.308e-108 0.43
MC3R_HUMAN MC3R Melanocortin receptor 3 1.124e-106 0.40
NK2R_RABIT TACR2 Substance-K receptor 1.855e-101 0.40
EDNRA_PIG EDNRA Endothelin-1 receptor 2.76e-80 0.44
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 6.203e-80 0.69
MC4R_MOUSE Mc4r Melanocortin receptor 4 8.057e-76 0.35
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 2.279e-72 0.70
MC4R_HUMAN MC4R Melanocortin receptor 4 1.632e-68 0.48
O07911_STAAU agrC AgrC 1.757e-64 0.37
V2R_PIG AVPR2 Vasopressin V2 receptor 2.942e-62 0.36
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 4.173e-62 0.38
EDNRA_MOUSE Ednra Endothelin-1 receptor 5.051e-61 0.34
NK2R_MESAU TACR2 Substance-K receptor 4.233e-60 0.40
MC3R_MOUSE Mc3r Melanocortin receptor 3 1.031e-58 0.35
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 4.912e-57 0.31
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 6.967e-52 0.70
V2R_BOVIN AVPR2 Vasopressin V2 receptor 9.017e-52 0.37
KISSR_HUMAN KISS1R KiSS-1 receptor 3.999e-51 0.32
NK2R_HUMAN TACR2 Substance-K receptor 5.128e-51 0.41
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.671e-50 0.34
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.584e-49 0.35
UR2R_RAT Uts2r Urotensin-2 receptor 3.74e-49 0.58
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 4.515e-49 0.46
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.59e-47 0.34
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 3.784e-47 0.33
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 9.908e-45 0.33
OPRM_RAT Oprm1 Mu-type opioid receptor 4.35e-44 0.58
NK2R_RAT Tacr2 Substance-K receptor 3.862e-43 0.36
GRPR_RAT Grpr Gastrin-releasing peptide receptor 1.567e-42 0.32
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 2.633e-40 0.33
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 3.457e-40 0.32
CADH2_HUMAN CDH2 Cadherin-2 1.921e-39 0.31
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.792e-39 0.40
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 1.06e-38 0.32
NK3R_RAT Tacr3 Neuromedin-K receptor 1.53e-38 0.36
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 2.247e-38 0.32
GALR1_RAT Galr1 Galanin receptor type 1 1.902e-37 0.30
GALR2_RAT Galr2 Galanin receptor type 2 1.902e-37 0.30
EDNRB_RAT Ednrb Endothelin receptor type B 7.685e-37 0.36
OPRD_RAT Oprd1 Delta-type opioid receptor 9.22e-37 0.51
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.408e-36 0.40
MC5R_HUMAN MC5R Melanocortin receptor 5 1.758e-36 0.40
SURA_ECOLI surA Chaperone SurA 3.875e-36 0.29
Q5D7U5_CHICK OXTR Oxytocin-like receptor 6.705e-36 0.28
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 2.409e-33 0.61
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 6.826e-32 0.37
OXYR_HUMAN OXTR Oxytocin receptor 7.792e-32 0.40
NK1R_CAVPO TACR1 Substance-P receptor 1.128e-30 0.36
CCKAR_RAT Cckar Cholecystokinin receptor type A 6.205e-30 0.31
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 9.311e-30 0.66
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 3.629e-29 0.70
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.221e-28 0.34
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.368e-27 0.40
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.925e-26 0.32
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.849e-26 0.35
FSHR_RAT Fshr Follicle-stimulating hormone receptor 7.913e-25 0.31
OXYR_RAT Oxtr Oxytocin receptor 9.752e-24 0.41
CP125_MYCTU cyp125 Steroid C26-monooxygenase 4.377e-23 0.28
NMBR_HUMAN NMBR Neuromedin-B receptor 4.35e-22 0.32
NEP_RABIT MME Neprilysin 5.072e-22 0.31
V2R_RAT Avpr2 Vasopressin V2 receptor 3.315e-21 0.41
ACE_RAT Ace Angiotensin-converting enzyme 9.027e-21 0.31
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 1.154e-20 0.35
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 2.111e-20 0.33
MMP11_MOUSE Mmp11 Stromelysin-3 2.676e-19 0.29
ELAS_PSEAE lasB Elastase 8.168e-19 0.33
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 9.504e-19 0.30
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.847e-18 0.41
V2R_HUMAN AVPR2 Vasopressin V2 receptor 2.413e-18 0.36
NK1R_RAT Tacr1 Substance-P receptor 4.48e-18 0.36
TYRO_HUMAN TYR Tyrosinase 4.616e-18 0.31
ECE1_RAT Ece1 Endothelin-converting enzyme 1 9.591e-18 0.30
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.698e-17 0.31
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 1.11e-16 0.39
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.11e-15 0.30
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.665e-15 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 9.326e-15 0.49
NK1R_HUMAN TACR1 Substance-P receptor 2.276e-14 0.41
A5A4K8_RABIT MLNR Motilin receptor 2.953e-14 0.29
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 5.029e-14 0.33
AGRA_STAAU agrA Accessory gene regulator protein A 5.973e-14 0.34
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.213e-13 0.41
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.874e-13 0.38
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.957e-13 0.40
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 3.155e-13 0.41
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 3.403e-13 0.32
ENV_HV1H2 env Envelope glycoprotein gp160 4.846e-13 0.28
OPRD_HUMAN OPRD1 Delta-type opioid receptor 7.072e-13 0.38
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 9.668e-13 0.33
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 1.309e-12 0.38
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 1.638e-12 0.29
NRP1_RAT Nrp1 Neuropilin-1 6.856e-12 0.29
ACE_HUMAN ACE Angiotensin-converting enzyme 7.597e-12 0.33
OPRM_HUMAN OPRM1 Mu-type opioid receptor 5.156e-11 0.38
RENI_HUMAN REN Renin 7.644e-11 0.40
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 1.584e-10 0.37
CHIB_SERMA chiB Chitinase B 1.82e-10 0.35
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.255e-10 0.32
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.472e-10 0.32
RENI_RAT Ren1 Renin 1.018e-09 0.38
MMP8_RAT Mmp8 Neutrophil collagenase 1.291e-09 0.30
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.494e-09 0.35
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.716e-09 0.31
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.216e-08 0.33
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.302e-08 0.29
ITB6_HUMAN ITGB6 Integrin beta-6 1.385e-08 0.35
ITA5_HUMAN ITGA5 Integrin alpha-5 2.368e-08 0.35
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.743e-08 0.32
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 2.88e-08 0.37
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.201e-08 0.40
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.454e-07 0.31
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.955e-07 0.30
CBX7_HUMAN CBX7 Chromobox protein homolog 7 3.105e-07 0.37
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 3.216e-07 0.31
CBPB2_HUMAN CPB2 Carboxypeptidase B2 5.818e-07 0.35
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.011e-06 0.29
HDA11_HUMAN HDAC11 Histone deacetylase 11 4.772e-06 0.35
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 6.75e-06 0.34
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 7.645e-06 0.34
HDAC1_HUMAN HDAC1 Histone deacetylase 1 9.207e-06 0.40

Piritramide

NPSR1_RAT Npsr1 Neuropeptide S receptor 5.351e-37 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 3.676e-31 0.53
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 1.908e-25 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.687e-24 0.62
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 2.276e-22 0.33
MEN1_HUMAN MEN1 Menin 1.11e-16 0.31
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 1.665e-15 0.31
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.887e-15 0.58
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 2.998e-15 0.31
CALM_BOVIN CALM Calmodulin 7.857e-13 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.59e-12 0.62
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.406e-09 0.38
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.2e-08 0.31
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.48e-08 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.613e-07 0.38
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.813e-06 0.37

Etripamil

MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 1.291e-36 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.359e-35 0.32
CAC1C_MOUSE Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.941e-26 0.33
HCN2_MOUSE Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 3.735e-21 0.34
AUR1_CANAL AUR1 Inositol phosphorylceramide synthase 1.064e-18 0.30
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 3.143e-18 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.22e-18 0.53
ERG2_YEAST ERG2 C-8 sterol isomerase 9.494e-18 0.53
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.885e-15 0.29
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 5.551e-15 0.29
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 9.992e-14 0.34
MOT1_RAT Slc16a1 Monocarboxylate transporter 1 2.082e-13 0.30
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 5.511e-12 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.032e-10 0.74
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.528e-10 0.74
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.55e-10 0.31
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.759e-10 0.74
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.706e-10 0.74
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 4.297e-10 0.74
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 7.965e-10 0.65
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 1.395e-09 0.74
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.402e-09 0.28
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 5.521e-09 0.37
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 2.998e-08 0.32
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 8.738e-08 0.74
LEP_ECOLI lepB Signal peptidase I 1.967e-07 0.29
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 1.072e-06 0.28
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.14e-06 0.34
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1.617e-06 0.30
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.918e-06 0.74
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 3.074e-06 0.34
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 3.082e-06 0.28
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.678e-06 0.33
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 7.395e-06 0.29

Omaveloxolone

CD81_HUMAN CD81 CD81 antigen 2.43e-36 0.29
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.061e-11 0.68

Nitrite

G3P_RABIT GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.882e-17 0.33