Results of Job: search_576a5ef2-ae4b-48de-935e-2b0039b8de4e

Query Target Key Target Name Description P-Value MaxTC

Pepstatin

PEPA_PIG PGA Pepsin A 3.569e-265 1.00
CATD_BOVIN CTSD Cathepsin D 4.457e-162 1.00
RENI_RAT Ren1 Renin 1.359e-81 1.00
Q95WR6_LEIDO Cysteine protease 2.714e-79 1.00
PEPA5_HUMAN PGA5 Pepsin A-5 4.468e-77 1.00
PLM1_PLAFA Plasmepsin-1 3.922e-68 1.00
CATD_HUMAN CTSD Cathepsin D 1.028e-63 1.00
RENI_HUMAN REN Renin 1.946e-56 1.00
PLM2_PLAFA Plasmepsin-2 4.22e-53 1.00
Q72874_9HIV1 pol Pol polyprotein 1.16e-33 1.00
CATE_HUMAN CTSE Cathepsin E 1.555e-32 1.00
CARP2_CANAX SAP2 Candidapepsin-2 3.937e-30 1.00
Q17SB2_PLAFA Plasmepsin 4 7.773e-24 1.00
Q9YQ12_9HIV1 protease Protease 4.075e-14 1.00
ADAM9_HUMAN ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 6.498e-12 1.00
CATB_HUMAN CTSB Cathepsin B 0.003214 1.00
POLG_HCV77 Genome polyprotein 0.111 1.00
CATL1_HUMAN CTSL Cathepsin L1 0.4311 1.00
Q8I6Z5_PLAF7 Plasmepsin V 5.685e-116 0.44
ECE1_RAT Ece1 Endothelin-converting enzyme 1 2.87e-106 0.51
DLG4_HUMAN DLG4 Disks large homolog 4 2.51e-98 0.38
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 2.481e-85 0.42
CARP_RHICH Rhizopuspepsin 2.516e-83 0.67
PEPA1_PENJA Penicillopepsin-1 1.349e-63 0.56
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 5.779e-54 0.35
A0A0H4FQ60_PLAVI Plasmepsin V 2.433e-48 0.38
RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 8.343e-45 0.35
CASP1_HUMAN CASP1 Caspase-1 3.411e-42 0.46
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 3.17e-38 0.31
PEPC_HUMAN PGC Gastricsin 1.97e-36 0.48
MMP20_HUMAN MMP20 Matrix metalloproteinase-20 1.609e-35 0.28
MMP24_HUMAN MMP24 Matrix metalloproteinase-24 1.609e-35 0.28
RENI1_MOUSE Ren1 Renin-1 1.816e-35 0.72
BACE1_HUMAN BACE1 Beta-secretase 1 7.936e-29 0.58
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 5.548e-28 0.45
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.048e-19 0.31
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.058e-19 0.45
FURIN_HUMAN FURIN Furin 1.543e-18 0.31
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 3.615e-18 0.29
IL1B_HUMAN IL1B Interleukin-1 beta 1.882e-17 0.33
ELAS_PSEAE lasB Elastase 6.328e-15 0.38
Q6UB75_PIG Group VII phospholipase A2 4.996e-14 0.30
NK2R_MESAU TACR2 Substance-K receptor 1.726e-13 0.30
CASP1_MOUSE Casp1 Caspase-1 4.745e-12 0.34
CASP3_HUMAN CASP3 Caspase-3 3.374e-11 0.39
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 7.43e-11 0.29
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 1.121e-10 0.29
CASP8_HUMAN CASP8 Caspase-8 3.3e-10 0.34
PAPA1_CARPA Papain 4.705e-10 0.31
O07911_STAAU agrC AgrC 1.815e-09 0.34
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 2.116e-09 0.35
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 2.116e-09 0.35
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 2.116e-09 0.35
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 2.116e-09 0.35
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 2.116e-09 0.35
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 2.116e-09 0.35
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 2.116e-09 0.35
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 2.116e-09 0.35
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 2.116e-09 0.35
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 2.116e-09 0.35
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 2.116e-09 0.35
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 2.116e-09 0.35
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 2.116e-09 0.35
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 2.714e-09 0.31
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 4.139e-09 0.35
MMP25_HUMAN MMP25 Matrix metalloproteinase-25 5.048e-09 0.28
CATB_BOVIN CTSB Cathepsin B 5.996e-09 0.90
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.279e-09 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.322e-08 0.29
Q4U254_9ENTO protease Protease 4.503e-08 0.86
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 4.565e-08 0.35
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 6.549e-08 0.35
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 9.415e-08 0.35
KLK5_HUMAN KLK5 Kallikrein-5 2.142e-07 0.34
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 3.083e-07 0.28
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 1.432e-06 0.35
CAN1_RAT Capn1 Calpain-1 catalytic subunit 1.664e-06 0.32
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.715e-06 0.35
CASP7_HUMAN CASP7 Caspase-7 1.923e-06 0.33
R1AB_SARS rep Replicase polyprotein 1ab 2.829e-06 0.32
DPEP1_PIG DPEP1 Dipeptidase 1 3.169e-06 0.33
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 8.755e-06 0.28

Cycloguanil

DYR_CHICK DHFR Dihydrofolate reductase 9.283e-248 1.00
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 1.677e-96 1.00
DYR_PNECA Dihydrofolate reductase 8.289e-32 1.00
DYR_HUMAN DHFR Dihydrofolate reductase 1.11e-16 1.00
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 2.72e-14 1.00
DYR_RAT Dhfr Dihydrofolate reductase 0.03909 1.00
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.229e-127 0.68
DYR_ECOLI folA Dihydrofolate reductase 7.512e-70 0.71
Q8I1R6_PLAF7 Bifunctional dihydrofolate reductase-thymidylate synthase 3.077e-50 0.40
DYR_LACCA folA Dihydrofolate reductase 3.36e-49 0.62
DYR_BOVIN DHFR Dihydrofolate reductase 5.398e-12 0.40

Chloroquine

HRP1_PLAFA Histidine-rich protein PFHRP-II 5.303e-175 1.00
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 2.9e-124 1.00
RBP_CHICK Riboflavin-binding protein 5.121e-61 1.00
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.968e-19 1.00
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 5.918e-10 1.00
A4_HUMAN APP Amyloid-beta precursor protein 1.949e-07 1.00
PRIO_HUMAN PRNP Major prion protein 6.054e-07 1.00
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 4.105e-05 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 6.405e-05 1.00
DYR_BOVIN DHFR Dihydrofolate reductase 0.0001402 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.004311 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.007862 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.01001 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.04204 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.05038 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.05063 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.07565 1.00
BACE1_HUMAN BACE1 Beta-secretase 1 0.9991 1.00
HNMT_HUMAN HNMT Histamine N-methyltransferase 1.032e-65 0.53
BXA1_CLOBO botA Botulinum neurotoxin type A 4.411e-58 0.56
GYRB_MYCS2 gyrB DNA gyrase subunit B 4.723e-50 0.30
HNMT_RAT Hnmt Histamine N-methyltransferase 8.595e-49 0.41
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.014e-28 0.53
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.235e-23 0.52
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 3.648e-20 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 9.37e-14 0.43
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 3.617e-13 0.35
AMP1_PLAFQ M1 family aminopeptidase 1.494e-10 0.39
PERL_BOVIN LPO Lactoperoxidase 4.011e-10 0.32
MEP2_YEAST MEP2 Ammonium transporter MEP2 4.661e-10 0.29
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 5.108e-10 0.32
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 7.541e-10 0.29
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.488e-07 0.29
TYTR_TRYCR TPR Trypanothione reductase 1.434e-06 0.61
DPOL_VACCW POL DNA polymerase 3.01e-06 0.31
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 8.364e-06 0.29

Amodiaquine

HNMT_HUMAN HNMT Histamine N-methyltransferase 2.9e-124 1.00
A4_HUMAN APP Amyloid-beta precursor protein 4.629e-08 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.1044 1.00
HRP1_PLAFA Histidine-rich protein PFHRP-II 1.015e-161 0.53
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.984e-86 0.34
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 1.032e-65 0.53
HNMT_RAT Hnmt Histamine N-methyltransferase 1.649e-49 0.44
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 4.193e-38 0.32
RBP_CHICK Riboflavin-binding protein 1.84e-32 0.53
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 3.256e-25 0.34
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 4.804e-22 0.36
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.313e-18 0.31
BXA1_CLOBO botA Botulinum neurotoxin type A 6.883e-15 0.43
AGP1_YEAST AGP1 General amino acid permease AGP1 4.03e-14 0.44
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 7.76e-14 0.53
DPOL_VACCW POL DNA polymerase 3.487e-13 0.35
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 9.931e-13 0.32
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.378e-12 0.39
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.42e-11 0.53
MEP2_YEAST MEP2 Ammonium transporter MEP2 2.131e-10 0.30
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 4.519e-09 0.44
AMP1_PLAFQ M1 family aminopeptidase 5.051e-09 0.33
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.473e-08 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 6.156e-08 0.38
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 1.201e-07 0.33
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 4.777e-07 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 7.296e-07 0.47
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 1.628e-06 0.32
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 2.258e-06 0.32
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.923e-06 0.48

Betulinic Acid

DPOLB_RAT Polb DNA polymerase beta 1.131e-63 1.00
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.78e-25 1.00
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 2.357e-17 1.00
Q9YQ12_9HIV1 protease Protease 7.147e-06 1.00
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 0.0005651 1.00
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 0.0006262 1.00
Q77YG1_9HIV1 gag Gag polyprotein 5.585e-81 0.67
CD81_HUMAN CD81 CD81 antigen 4.556e-46 0.37
DHI2_RAT Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.092e-44 0.35
Q43445_SOYBN Methyltransferase 6.705e-36 0.28
PA2A1_ECHCA Acidic phospholipase A2 EC-I 1.78e-34 0.43
PA2B1_NAJME Basic phospholipase A2 1 1.78e-34 0.43
PA2BA_PROFL Basic phospholipase A2 PLA-A 1.78e-34 0.43
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 5.786e-27 0.53
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 1.875e-23 0.72
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 2.073e-22 0.43
IL1B_HUMAN IL1B Interleukin-1 beta 1.122e-17 0.34
TF65_HUMAN RELA Transcription factor p65 1.11e-16 0.75
POL_HV1H2 gag-pol Gag-Pol polyprotein 5.551e-16 0.67
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.107e-15 0.35
TF_HUMAN F3 Tissue factor 4.314e-13 0.68
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.966e-10 0.60
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.45e-09 0.36
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 7.407e-08 0.32
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 9.508e-08 0.46
DPOLB_HUMAN POLB DNA polymerase beta 4.01e-07 0.43
EST2_HUMAN CES2 Cocaine esterase 4.899e-07 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.047e-06 0.43

Quinidine

KCND2_RAT Kcnd2 Potassium voltage-gated channel subfamily D member 2 5.121e-61 1.00
S22A2_MOUSE Slc22a2 Solute carrier family 22 member 2 5.121e-61 1.00
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 6.524e-44 1.00
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.524e-44 1.00
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 4.875e-41 1.00
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.712e-23 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.016e-09 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.249e-07 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0002896 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 0.07391 1.00
CHLE_HORSE BCHE Cholinesterase 0.2573 1.00
CHLE_HUMAN BCHE Cholinesterase 0.2814 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.7175 1.00
GYRA_STAAU gyrA DNA gyrase subunit A 5.287e-71 0.45
GYRB_STAAU gyrB DNA gyrase subunit B 3.299e-44 0.45
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 6.252e-27 0.38
GYRB_MYCSM gyrB DNA gyrase subunit B 2.344e-11 0.31
O97467_PLAFA ht1 Hexose transporter 1 1.153e-09 0.41
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 1.088e-08 0.31
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 8.282e-06 0.31

Quinine

KCND2_RAT Kcnd2 Potassium voltage-gated channel subfamily D member 2 5.121e-61 1.00
S22A2_MOUSE Slc22a2 Solute carrier family 22 member 2 5.121e-61 1.00
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 6.524e-44 1.00
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.524e-44 1.00
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 4.875e-41 1.00
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.712e-23 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.016e-09 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.249e-07 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0002896 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 0.07391 1.00
CHLE_HORSE BCHE Cholinesterase 0.2573 1.00
CHLE_HUMAN BCHE Cholinesterase 0.2814 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.7175 1.00
GYRA_STAAU gyrA DNA gyrase subunit A 5.287e-71 0.45
GYRB_STAAU gyrB DNA gyrase subunit B 3.299e-44 0.45
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 6.252e-27 0.38
GYRB_MYCSM gyrB DNA gyrase subunit B 2.344e-11 0.31
O97467_PLAFA ht1 Hexose transporter 1 1.153e-09 0.41
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 1.088e-08 0.31
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 8.282e-06 0.31

Primaquine

PERL_BOVIN LPO Lactoperoxidase 3.937e-30 1.00
CASP6_HUMAN CASP6 Caspase-6 1.925e-06 1.00
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 3.75e-06 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 6.485e-06 1.00
PERM_HUMAN MPO Myeloperoxidase 0.0001999 1.00
RECA_MYCTU recA Protein RecA 0.0004927 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.0008604 1.00
CASP7_HUMAN CASP7 Caspase-7 0.003257 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.501 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.5147 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.9982 1.00
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.968e-41 0.48
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 3.824e-40 0.32
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 2.776e-23 0.37
HASP_HUMAN HASPIN Serine/threonine-protein kinase haspin 1.08e-21 0.31
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 4.416e-20 0.45
RBP_CHICK Riboflavin-binding protein 5.429e-20 0.32
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 9.187e-18 0.33
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 5.474e-17 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 2.22e-16 0.37
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.101e-11 0.44
HRP1_PLAFA Histidine-rich protein PFHRP-II 7.18e-10 0.66
PDE4A_HUMAN PDE4A cAMP-specific 3',5'-cyclic phosphodiesterase 4A 1.486e-07 0.37
TF65_HUMAN RELA Transcription factor p65 2.636e-07 0.45
PLM1_PLAFA Plasmepsin-1 3.894e-07 0.43
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 7.633e-07 0.32
S10A4_HUMAN S100A4 Protein S100-A4 7.758e-07 0.46
BXA1_CLOBO botA Botulinum neurotoxin type A 9.613e-07 0.33
DYR1_ECOLX dhfrI Dihydrofolate reductase type 1 2.577e-06 0.33
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 3.126e-06 0.60
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 6.855e-06 0.37
STABP_HUMAN STAMBP STAM-binding protein 8.994e-06 0.29

Hydroxychloroquine

SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.968e-19 1.00
TLR9_HUMAN TLR9 Toll-like receptor 9 0.0007443 1.00
TLR7_HUMAN TLR7 Toll-like receptor 7 0.001556 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.001661 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.004311 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.01148 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.05785 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.06911 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.2541 1.00
HRP1_PLAFA Histidine-rich protein PFHRP-II 4.174e-164 0.86
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 5.433e-107 0.86
HNMT_HUMAN HNMT Histamine N-methyltransferase 1.484e-63 0.51
BXA1_CLOBO botA Botulinum neurotoxin type A 5.112e-56 0.52
RBP_CHICK Riboflavin-binding protein 1.359e-52 0.86
HNMT_RAT Hnmt Histamine N-methyltransferase 2.688e-45 0.38
GYRB_MYCS2 gyrB DNA gyrase subunit B 2.047e-43 0.29
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.707e-25 0.47
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.311e-17 0.45
AGP1_YEAST AGP1 General amino acid permease AGP1 1.683e-13 0.42
CAS1_ARATH CAS1 Cycloartenol synthase 4.073e-13 0.32
ERG7_YEAST ERG7 Lanosterol synthase 4.073e-13 0.32
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 4.959e-13 0.34
ABCC8_RAT Abcc8 ATP-binding cassette sub-family C member 8 2.434e-12 0.29
AMP1_PLAFQ M1 family aminopeptidase 2.19e-10 0.39
MEP2_YEAST MEP2 Ammonium transporter MEP2 5.575e-10 0.29
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 8.811e-10 0.28
PERL_BOVIN LPO Lactoperoxidase 1.823e-09 0.30
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 3.118e-09 0.86
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 6.138e-09 0.30
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 7.984e-09 0.32
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 1.238e-07 0.30
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 1.238e-07 0.30
LSS_HUMAN LSS Lanosterol synthase 1.725e-07 0.32
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 2.663e-07 0.32
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 2.663e-07 0.32
NICA_HUMAN NCSTN Nicastrin 2.663e-07 0.32
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 2.682e-07 0.32
PSN2_HUMAN PSEN2 Presenilin-2 2.739e-07 0.32
PSN1_HUMAN PSEN1 Presenilin-1 5.293e-07 0.32
A4_HUMAN APP Amyloid-beta precursor protein 5.908e-07 0.86
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 9.576e-07 0.30
PRIO_HUMAN PRNP Major prion protein 2.315e-06 0.86
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 6.522e-06 0.30
TYTR_TRYCR TPR Trypanothione reductase 7.527e-06 0.53
DPOL_VACCW POL DNA polymerase 7.77e-06 0.28

Dapsone

5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.189e-11 1.00
DYR_PNECA Dihydrofolate reductase 0.009287 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.519e-68 0.65
B2V8E3_SULSY Carbonate dehydratase 7.502e-68 0.65
Q31FD6_HYDCU Carbonic anhydrase, alpha family 7.502e-68 0.65
C0IX24_STYPI CA2 Carbonic anhydrase 2.647e-66 0.65
B5SU02_STYPI CA Alpha carbonic anhydrase 9.517e-64 0.65
CAH_METTE Carbonic anhydrase 1.758e-63 0.65
A6YCJ1_9METZ Astrosclerin-3 7.824e-63 0.65
CYNT_HELPY cynT Carbonic anhydrase 2.881e-58 0.65
Q5TU56_ANOGA 1272966 Carbonic anhydrase 4.624e-56 0.65
CAN_YEAST NCE103 Carbonic anhydrase 2.375e-51 0.41
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 8.54e-45 0.65
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.707e-40 0.65
CAH2_BOVIN CA2 Carbonic anhydrase 2 7.327e-40 0.65
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.184e-36 0.65
Q6FTL6_CANGA NCE103 Carbonic anhydrase 2.484e-36 0.65
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.777e-32 0.65
CAN_CANAL NCE103 Carbonic anhydrase 1.446e-29 0.65
Q5VLE3_EMEND rmtA RmtA 3.507e-26 0.42
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.914e-25 0.65
Q9HVB9_PSEAE Carbonic anhydrase 3.931e-23 0.37
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 7.533e-22 0.65
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 2.028e-20 0.39
5NTD_HUMAN NT5E 5'-nucleotidase 2.564e-18 0.62
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.784e-18 0.65
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 5.228e-18 0.41
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 5.75e-18 0.65
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.947e-17 0.41
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.11e-16 0.65
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 2.22e-16 0.31
CAH12_HUMAN CA12 Carbonic anhydrase 12 4.441e-16 0.65
CAH9_HUMAN CA9 Carbonic anhydrase 9 6.661e-16 0.65
METC_ECOLI metC Cystathionine beta-lyase MetC 7.105e-15 0.32
CAH7_HUMAN CA7 Carbonic anhydrase 7 9.437e-15 0.65
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.675e-13 0.43
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.635e-13 0.35
CAH4_HUMAN CA4 Carbonic anhydrase 4 9.783e-13 0.65
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.892e-12 0.65
CAH3_HUMAN CA3 Carbonic anhydrase 3 8.277e-12 0.65
CAH4_BOVIN CA4 Carbonic anhydrase 4 1.86e-11 0.65
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.045e-09 0.28
R1A_SARS Replicase polyprotein 1a 2.694e-09 0.34
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 3.582e-09 0.34
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.607e-08 0.28
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 6.381e-08 0.31
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 6.381e-08 0.31
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 3.379e-07 0.42
CAH13_HUMAN CA13 Carbonic anhydrase 13 5.847e-07 0.65
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 9.129e-07 0.32
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 9.501e-07 0.31

Pyronaridine

PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 3.347e-06 1.00
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 5.212e-06 1.00
TERT_HUMAN TERT Telomerase reverse transcriptase 1.419e-48 0.37
HNMT_RAT Hnmt Histamine N-methyltransferase 2.537e-43 0.35
HNMT_HUMAN HNMT Histamine N-methyltransferase 8.297e-37 0.29
ENL_HUMAN MLLT1 Protein ENL 2.258e-25 0.31
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 1.974e-22 0.38
TOP2_PLAFK TOP2 DNA topoisomerase 2 1.985e-19 0.31
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 2.817e-19 0.31
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.565e-14 0.32
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 5.558e-13 0.32
ACES_BOVIN ACHE Acetylcholinesterase 8.721e-13 0.39
HRP1_PLAFA Histidine-rich protein PFHRP-II 6.378e-12 0.31
ACES_ELEEL ache Acetylcholinesterase 2.521e-11 0.39
CHLE_HORSE BCHE Cholinesterase 2.792e-11 0.39
TYTR_TRYCR TPR Trypanothione reductase 6.062e-11 0.35
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 1.705e-09 0.32
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.705e-09 0.32
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.131e-09 0.34
CHLE_HUMAN BCHE Cholinesterase 4.836e-09 0.37
TYTR_TRYBB TPR Trypanothione reductase 5.525e-09 0.31
ACES_HUMAN ACHE Acetylcholinesterase 9.4e-09 0.39
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.439e-07 0.37
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.471e-07 0.36
GPR6_HUMAN GPR6 G-protein coupled receptor 6 2.992e-07 0.32
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 6.699e-07 0.32
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.186e-06 0.28
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.191e-06 0.34
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.21e-06 0.28
HMOX2_RAT Hmox2 Heme oxygenase 2 1.688e-06 0.31

Lumefantrine

KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.00777 1.00
PGH2_RABIT PTGS2 Prostaglandin G/H synthase 2 2.22e-16 0.28
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 3.027e-12 0.34
PGH1_RABIT PTGS1 Prostaglandin G/H synthase 1 4.155e-09 0.28

Quinacrine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.04696 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.3042 1.00
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 1.516e-68 0.55
HNMT_HUMAN HNMT Histamine N-methyltransferase 1.007e-38 0.31
RBP_CHICK Riboflavin-binding protein 7.641e-34 0.55
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.322e-30 0.59
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 5.444e-26 0.47
HRP1_PLAFA Histidine-rich protein PFHRP-II 4.909e-24 0.55
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 8.14e-21 0.32
TOP2_PLAFK TOP2 DNA topoisomerase 2 1.369e-20 0.33
TYTR_TRYCR TPR Trypanothione reductase 1.247e-19 0.94
ACES_BOVIN ACHE Acetylcholinesterase 2.244e-19 0.45
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.11e-16 0.29
CHLE_HUMAN BCHE Cholinesterase 2.22e-16 0.37
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 2.22e-16 0.29
ACES_HUMAN ACHE Acetylcholinesterase 3.331e-16 0.37
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 5.44e-15 0.29
DYR_BOVIN DHFR Dihydrofolate reductase 7.783e-14 0.55
CHLE_HORSE BCHE Cholinesterase 1.268e-13 0.45
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 1.081e-12 0.32
ACES_ELEEL ache Acetylcholinesterase 4.548e-12 0.38
NTR2_RAT Ntsr2 Neurotensin receptor type 2 3.083e-11 0.30
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.388e-11 0.55
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 5.329e-11 0.29
PERL_BOVIN LPO Lactoperoxidase 3.683e-10 0.32
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 4.627e-09 0.44
NDKB_HUMAN NME2 Nucleoside diphosphate kinase B 6.943e-09 0.30
DPO1_THEAQ polA DNA polymerase I, thermostable 3.631e-08 0.32
CRFR1_HUMAN CRHR1 Corticotropin-releasing factor receptor 1 6.47e-08 0.31
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 6.113e-07 0.55
DPOL_VACCW POL DNA polymerase 1.176e-06 0.33
AGP1_YEAST AGP1 General amino acid permease AGP1 1.801e-06 0.32
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.463e-06 0.28
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 5.887e-06 0.45
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 7.355e-06 0.29

Mefloquine

AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.064 1.00
AA1R_HUMAN ADORA1 Adenosine receptor A1 0.2103 1.00
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 0.6893 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.7724 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9869 1.00
IDHP_HUMAN IDH2 Isocitrate dehydrogenase [NADP], mitochondrial 1.321e-14 0.29
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.228e-14 0.37
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.292e-12 0.39
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 7.431e-11 0.39
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 6.528e-07 0.34
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 7.334e-07 0.34

Halofantrine

Q8IL32_PLAF7 Heat shock protein 90, putative 0.1267 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.6311 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.6738 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
RORB_HUMAN RORB Nuclear receptor ROR-beta 1.219e-11 0.34
RORA_HUMAN RORA Nuclear receptor ROR-alpha 8.321e-10 0.34

Artemisinin

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.901 1.00
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.253e-23 0.36

Piperaquine

HRP1_PLAFA Histidine-rich protein PFHRP-II 6.335e-188 0.53
GYRB_MYCS2 gyrB DNA gyrase subunit B 9.07e-159 0.59
HNMT_RAT Hnmt Histamine N-methyltransferase 5.449e-107 0.55
DRD4_RAT Drd4 D(4) dopamine receptor 1.388e-90 0.38
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 7.659e-86 0.42
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.198e-82 0.55
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.141e-78 0.55
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.051e-77 0.56
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 6.905e-71 0.40
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.179e-65 0.56
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 4.153e-59 0.60
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.974e-55 0.40
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.179e-54 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 7.489e-51 0.55
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.133e-48 0.32
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 4.538e-44 0.35
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 3.874e-42 0.38
HNMT_HUMAN HNMT Histamine N-methyltransferase 4.694e-40 0.32
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 1.417e-37 0.38
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.262e-34 0.38
DRD1_PIG DRD1 D(1A) dopamine receptor 2.231e-32 0.35
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 5.097e-32 0.41
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.376e-32 0.39
H10_HUMAN H1-0 Histone H1.0 2.898e-30 0.30
SL9A3_RAT Slc9a3 Sodium/hydrogen exchanger 3 2.439e-29 0.34
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.256e-29 0.40
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.725e-27 0.41
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 6.435e-27 0.41
DRD3_RAT Drd3 D(3) dopamine receptor 3.116e-26 0.40
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 7.027e-26 0.33
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 5.838e-25 0.38
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.254e-25 0.47
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.531e-24 0.39
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 4.042e-24 0.35
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 8.573e-24 0.34
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.239e-23 0.29
RBP_CHICK Riboflavin-binding protein 6.61e-22 0.35
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 8.481e-22 0.38
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.492e-20 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.188e-20 0.41
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.657e-19 0.33
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 1.827e-19 0.34
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.813e-19 0.38
HRH4_HUMAN HRH4 Histamine H4 receptor 3.26e-19 0.39
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.011e-19 0.40
HRH3_CAVPO HRH3 Histamine H3 receptor 5.986e-19 0.48
CASP5_HUMAN CASP5 Caspase-5 1.11e-16 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.551e-16 0.41
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.551e-16 0.40
AGP1_YEAST AGP1 General amino acid permease AGP1 2.887e-15 0.43
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 3.442e-15 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.441e-15 0.38
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 6.772e-15 0.31
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 9.548e-15 0.36
MEP2_YEAST MEP2 Ammonium transporter MEP2 2.709e-14 0.43
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.552e-14 0.55
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 8.327e-14 0.39
DRD1_RAT Drd1 D(1A) dopamine receptor 9.426e-14 0.39
HRH1_HUMAN HRH1 Histamine H1 receptor 9.592e-14 0.38
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.549e-13 0.30
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.842e-13 0.29
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 3.284e-13 0.35
GPR6_HUMAN GPR6 G-protein coupled receptor 6 1.853e-12 0.33
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.218e-12 0.30
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 3.069e-12 0.36
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 4.959e-12 0.29
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 4.959e-12 0.29
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.148e-11 0.38
NTR1_RAT Ntsr1 Neurotensin receptor type 1 1.283e-11 0.31
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.35e-11 0.35
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.36e-11 0.34
HRH3_HUMAN HRH3 Histamine H3 receptor 2.262e-11 0.55
AMP1_PLAFQ M1 family aminopeptidase 5.143e-11 0.41
US28_HCMVA US28 G-protein coupled receptor homolog US28 6.135e-11 0.29
CHKA_HUMAN CHKA Choline kinase alpha 1.018e-10 0.33
BXA1_CLOBO botA Botulinum neurotoxin type A 1.229e-10 0.42
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 5.969e-10 0.30
THAS_RAT Tbxas1 Thromboxane-A synthase 8.077e-10 0.31
CASP4_HUMAN CASP4 Caspase-4 8.112e-10 0.30
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.28e-09 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 1.916e-09 0.33
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 2.269e-09 0.48
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.635e-09 0.29
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 3.091e-09 0.30
ACES_ELEEL ache Acetylcholinesterase 3.948e-09 0.33
HD_HUMAN HTT Huntingtin 4.205e-09 0.40
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 5.897e-09 0.30
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 8.173e-09 0.29
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 8.173e-09 0.29
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 9.882e-09 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 2.627e-08 0.48
DRD3_CHLAE DRD3 D(3) dopamine receptor 3.032e-08 0.29
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.09e-08 0.38
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 7.869e-08 0.33
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 9.285e-08 0.31
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.196e-07 0.32
DRD1_BOVIN DRD1 D(1A) dopamine receptor 1.863e-07 0.31
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.418e-07 0.38
DHSO_HUMAN SORD Sorbitol dehydrogenase 3.936e-07 0.29
SL9A3_HUMAN SLC9A3 Sodium/hydrogen exchanger 3 6.271e-07 0.32
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.893e-06 0.34
DPOL_VACCW POL DNA polymerase 1.907e-06 0.32
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.028e-06 0.29
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 2.772e-06 0.45
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 2.952e-06 0.31
GLI1_MOUSE Gli1 Zinc finger protein GLI1 3.256e-06 0.60
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 3.77e-06 0.29
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 4.681e-06 0.38
G3I1B6_CRIGR 5-hydroxytryptamine receptor 6.91e-06 0.29
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 8.048e-06 0.29
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 9.013e-06 0.34

Mizoribine

AA1R_RAT Adora1 Adenosine receptor A1 3.008e-175 0.49
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 3.723e-156 0.42
ADOK_MYCTO adoK Adenosine kinase 2.263e-153 0.41
ADK_TOXGO AK Adenosine kinase 1.458e-145 0.50
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 7.705e-139 0.38
AA1R_CHICK ADORA1 Adenosine receptor A1 1.486e-117 0.41
CDD_MOUSE Cda Cytidine deaminase 9.761e-116 0.49
AA1R_RABIT ADORA1 Adenosine receptor A1 6.263e-110 0.34
AA3R_RABIT ADORA3 Adenosine receptor A3 5.8e-108 0.34
AA2AR_RAT Adora2a Adenosine receptor A2a 3.729e-107 0.50
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 2.667e-105 0.35
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 2.13e-100 0.35
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.866e-98 0.35
C3SIU2_ECOLX metJ Met repressor 4.905e-95 0.34
CDD_HUMAN CDA Cytidine deaminase 4.498e-93 0.49
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 3.011e-88 0.35
AA1R_CAVPO ADORA1 Adenosine receptor A1 7.482e-85 0.50
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.687e-83 0.50
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 5.283e-79 0.35
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 6.231e-78 0.35
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 1.64e-74 0.38
AA3R_RAT Adora3 Adenosine receptor A3 6.976e-71 0.50
P2RY1_RAT P2ry1 P2Y purinoceptor 1 1.724e-70 0.35
ADK_HUMAN ADK Adenosine kinase 3.276e-68 0.51
AA1R_HUMAN ADORA1 Adenosine receptor A1 6.781e-67 0.50
SPEE_HUMAN SRM Spermidine synthase 8.407e-65 0.34
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 3.488e-63 0.31
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 1.46e-58 0.33
SAHH_HUMAN AHCY Adenosylhomocysteinase 2.633e-58 0.49
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 2.676e-58 0.33
Q99MI5_RAT LOC100912604 Spermidine synthase 1.07e-57 0.34
PUR6_CHICK AIRC Multifunctional protein ADE2 5.976e-57 0.37
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 4.786e-56 0.34
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 8.41e-55 0.51
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.019e-54 0.38
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 1.922e-54 0.30
PQSA_PSEAE pqsA Anthranilate--CoA ligase 3.686e-53 0.34
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 8.437e-52 0.33
SPSY_HUMAN SMS Spermine synthase 9.092e-52 0.34
RASK_HUMAN KRAS GTPase KRas 1.744e-51 0.32
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 2.059e-51 0.32
ENTE_ECOLI entE Enterobactin synthase component E 2.133e-51 0.32
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 5.972e-50 0.35
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 2.275e-49 0.50
NADK_HUMAN NADK NAD kinase 7.451e-48 0.31
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 7.888e-48 0.31
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 4.79e-47 0.40
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 2.109e-45 0.47
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 1.522e-44 0.35
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 1.522e-44 0.35
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 6.98e-44 0.35
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 6.98e-44 0.35
NADK1_LISMF nadK1 NAD kinase 1 9.991e-44 0.35
NADK_STAAC nadK NAD kinase 9.991e-44 0.35
SYS_ECOLI serS Serine--tRNA ligase 3.453e-43 0.34
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 1.204e-42 0.34
WALK_STAAU walK Sensor protein kinase WalK 1.204e-42 0.34
ADA_BOVIN ADA Adenosine deaminase 4.572e-42 0.49
ENPL_PIG HSP90B1 Endoplasmin 5.166e-42 0.33
P2RY4_RAT P2ry4 P2Y purinoceptor 4 6.473e-42 0.35
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 6.951e-42 0.31
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 1.89e-41 0.33
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1.998e-41 0.33
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5.715e-41 0.34
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 2.671e-40 0.32
SYD_ECOLI aspS Aspartate--tRNA ligase 9.26e-40 0.32
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 1.157e-39 0.31
SYY_ECOLI tyrS Tyrosine--tRNA ligase 2.419e-39 0.31
P2RX5_RAT P2rx5 P2X purinoceptor 5 2.739e-39 0.33
P2RX6_RAT P2rx6 P2X purinoceptor 6 2.739e-39 0.33
ADA_MOUSE Ada Adenosine deaminase 3.038e-39 0.49
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 1.217e-37 0.35
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.381e-37 0.40
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 1.443e-37 0.30
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 5.968e-37 0.34
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.648e-36 0.34
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 2.333e-36 0.29
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 1.097e-35 0.28
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 2.282e-34 0.45
KITH_VZVD TK Thymidine kinase 2.9e-33 0.37
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 1.013e-31 0.39
ADA_HUMAN ADA Adenosine deaminase 1.536e-31 0.49
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 1.428e-30 0.38
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 1.714e-30 0.34
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 2.078e-30 0.31
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 4.356e-30 0.30
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 2.984e-28 0.35
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 3.829e-28 0.35
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 5.242e-28 0.32
AMPD1_RABIT AMPD1 AMP deaminase 1 7.288e-28 0.34
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 2.991e-27 0.33
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 6.779e-27 0.40
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 2.426e-25 0.31
SYL_ECOLI leuS Leucine--tRNA ligase 3.063e-25 0.31
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 4.485e-25 0.55
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 9.384e-25 0.34
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 3.516e-24 0.30
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 6.009e-24 0.30
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 1.734e-23 0.29
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 5.518e-23 0.28
Q4VQ11_PIG Adenosine receptor A1 4.468e-22 0.43
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 7.378e-22 0.35
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 7.826e-22 0.43
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 1.309e-21 0.31
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 4.832e-21 0.33
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 7.127e-21 0.37
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 1.377e-20 0.40
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 4.045e-20 0.37
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 4.441e-20 0.47
GLCM_BOVIN GBA Lysosomal acid glucosylceramidase 8.656e-20 0.31
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 1.329e-19 0.35
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.381e-19 0.31
SAHH_RAT Ahcy Adenosylhomocysteinase 1.479e-19 0.33
SYI_ECOLI ileS Isoleucine--tRNA ligase 1.507e-19 0.31
PANC_MYCTU panC Pantothenate synthetase 2.385e-19 0.34
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 9.803e-19 0.30
Q8TA74_HEMPU Ryanodine receptor 2.749e-18 0.29
P2RX4_RAT P2rx4 P2X purinoceptor 4 2.798e-18 0.33
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 3.334e-18 0.29
KITH_RAT Tk1 Thymidine kinase, cytosolic 6.109e-18 0.28
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 7.054e-18 0.31
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 3.952e-17 0.33
B4EH87_BURCJ Lectin 1.11e-16 0.32
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.11e-16 0.30
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.11e-16 0.36
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.11e-16 0.47
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 1.554e-15 0.30
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 3.331e-15 0.36
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 4.33e-15 0.34
Q9HX69_PSEAE rocR RocR 4.441e-15 0.29
KITH_HUMAN TK1 Thymidine kinase, cytosolic 6.439e-15 0.35
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 8.882e-15 0.37
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.266e-14 0.30
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.676e-14 0.35
CD69_HUMAN CD69 Early activation antigen CD69 5.318e-14 0.34
CCNK_HUMAN CCNK Cyclin-K 6.672e-14 0.38
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 1.011e-13 0.34
AA1R_BOVIN ADORA1 Adenosine receptor A1 2.724e-13 0.47
AA2AR_MOUSE Adora2a Adenosine receptor A2a 3.922e-13 0.29
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 4.865e-13 0.35
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.149e-12 0.43
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 3.108e-12 0.32
TYPH_HUMAN TYMP Thymidine phosphorylase 4.509e-12 0.35
ADCY2_RAT Adcy2 Adenylate cyclase type 2 6.127e-12 0.32
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 6.903e-12 0.32
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.633e-11 0.34
P2RX1_RAT P2rx1 P2X purinoceptor 1 2.061e-11 0.32
SAHH_MOUSE Ahcy Adenosylhomocysteinase 2.363e-11 0.31
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 3.293e-11 0.31
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 8.211e-11 0.34
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 1.035e-10 0.34
ADK_RAT Adk Adenosine kinase 2.889e-10 0.39
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.082e-10 0.38
HXK2_HUMAN HK2 Hexokinase-2 5.92e-10 0.28
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 7.028e-10 0.35
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.901e-09 0.35
AA1R_MOUSE Adora1 Adenosine receptor A1 2.498e-09 0.43
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 3.572e-09 0.37
HXK1_HUMAN HK1 Hexokinase-1 5.537e-09 0.28
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 6.035e-09 0.38
CAH9_HUMAN CA9 Carbonic anhydrase 9 6.669e-09 0.39
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 1.309e-08 0.32
E1BN64_BOVIN PDE3B Phosphodiesterase 1.322e-08 0.29
DCPS_HUMAN DCPS m7GpppX diphosphatase 2.654e-08 0.32
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 3.477e-08 0.35
INMT_HUMAN INMT Indolethylamine N-methyltransferase 3.477e-08 0.35
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 3.567e-08 0.51
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.896e-08 0.42
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.186e-08 0.38
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 8.436e-08 0.38
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.413e-07 0.39
IL6_HUMAN IL6 Interleukin-6 1.436e-07 0.30
LEG9_HUMAN LGALS9 Galectin-9 3.044e-07 0.32
5NTD_RAT Nt5e 5'-nucleotidase 3.393e-07 0.34
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 4.171e-07 0.32
5NTD_HUMAN NT5E 5'-nucleotidase 4.769e-07 0.34
CAH2_HUMAN CA2 Carbonic anhydrase 2 8.432e-07 0.39
OGA_HUMAN OGA Protein O-GlcNAcase 9.777e-07 0.30
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 9.875e-07 0.33
P2Y12_RAT P2ry12 P2Y purinoceptor 12 1.456e-06 0.34
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.52e-06 0.31
SYT_YERPE thrS Threonine--tRNA ligase 1.756e-06 0.32
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 3.214e-06 0.30
ENPL_CANLF HSP90B1 Endoplasmin 3.596e-06 0.33
P2RX2_RAT P2rx2 P2X purinoceptor 2 6.478e-06 0.33
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 6.788e-06 0.30

Naphthoquine

HRP1_PLAFA Histidine-rich protein PFHRP-II 9.957e-172 0.40
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.745e-78 0.34
HNMT_HUMAN HNMT Histamine N-methyltransferase 5.734e-57 0.45
HNMT_RAT Hnmt Histamine N-methyltransferase 8.962e-54 0.42
Q9NAW2_PLAFA Cysteine proteinase falcipain 2a 1.371e-45 0.36
ACES_TETCF ache Acetylcholinesterase 5.158e-33 0.35
ACES_BOVIN ACHE Acetylcholinesterase 7.106e-32 0.33
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 5.282e-31 0.34
CHLE_HUMAN BCHE Cholinesterase 1.289e-23 0.37
RBP_CHICK Riboflavin-binding protein 1.199e-22 0.36
BXA1_CLOBO botA Botulinum neurotoxin type A 1.945e-19 0.42
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 2.301e-18 0.29
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1.357e-17 0.35
ACES_HUMAN ACHE Acetylcholinesterase 3.19e-17 0.38
ACES_ELEEL ache Acetylcholinesterase 4.341e-14 0.38
AGP1_YEAST AGP1 General amino acid permease AGP1 7.87e-13 0.35
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 3.433e-12 0.39
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 4.019e-12 0.30
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 3.558e-11 0.30
MEP2_YEAST MEP2 Ammonium transporter MEP2 4.775e-11 0.32
AMP1_PLAFQ M1 family aminopeptidase 4.944e-09 0.33
CHLE_HORSE BCHE Cholinesterase 9.865e-09 0.38
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 6.709e-08 0.36
DPOL_VACCW POL DNA polymerase 4.184e-06 0.30
A4_HUMAN APP Amyloid-beta precursor protein 6.471e-06 0.50
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 7.757e-06 0.35
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 8.543e-06 0.29

Pyrimethamine

DYR_RAT Dhfr Dihydrofolate reductase 4.047e-98 0.69
J7IFZ2_STRPY Dihydrofolate reductase 3.107e-74 0.38
DYR_STAAU folA Dihydrofolate reductase 3.728e-57 0.38
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 5.069e-57 0.63
DYR_PNECA Dihydrofolate reductase 2.833e-54 0.63
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 6.276e-48 0.78
DYR_CANAX DFR1 Dihydrofolate reductase 5.848e-41 0.41
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 2.244e-40 0.72
DYR_HUMAN DHFR Dihydrofolate reductase 4.52e-40 0.51
Q81R22_BACAN dfrA Dihydrofolate reductase 1.091e-38 0.41
O30463_MYCAV folA Dihydrofolate reductase 3.195e-32 0.43
DYR_YEAST DFR1 Dihydrofolate reductase 6.862e-28 0.32
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 1.9e-19 0.49
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 5.084e-17 0.30
ADK_HUMAN ADK Adenosine kinase 3.775e-15 0.38
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 6.828e-14 0.33
DYR_MYCTU folA Dihydrofolate reductase 4.245e-13 0.36
RENI_HUMAN REN Renin 1.815e-12 0.54
Q8Z9J9_SALTI folA Dihydrofolate reductase 2.762e-12 0.38
DRTS_PLABA Bifunctional dihydrofolate reductase-thymidylate synthase 2.91e-11 0.33
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.766e-10 0.30
DPP2_RAT Dpp7 Dipeptidyl peptidase 2 3.484e-10 0.30
DYR_LACCA folA Dihydrofolate reductase 3.296e-09 0.48
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 3.884e-09 0.33
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 6.287e-07 0.34
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 3.889e-06 0.59
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 5.619e-06 0.30

Acedapsone

PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 7.047e-96 0.39
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 2.209e-93 0.39
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.974e-83 0.70
DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 5.293e-82 0.42
CAH1_HUMAN CA1 Carbonic anhydrase 1 4.217e-79 0.63
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 3.116e-78 0.49
UT1_RAT Slc14a1 Urea transporter 1 2.516e-73 0.48
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.956e-73 0.49
CAH4_BOVIN CA4 Carbonic anhydrase 4 1.025e-64 0.70
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.171e-64 0.70
CAH12_HUMAN CA12 Carbonic anhydrase 12 3.401e-64 0.70
PSBA_MARPO psbA Photosystem II protein D1 1.129e-60 0.35
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.232e-59 0.62
UT2_RAT Slc14a2 Urea transporter 2 2.973e-54 0.48
Q6FTL6_CANGA NCE103 Carbonic anhydrase 6.961e-54 0.44
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.083e-52 0.47
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 2.639e-48 0.57
TGM1_HUMAN TGM1 Protein-glutamine gamma-glutamyltransferase K 2.703e-47 0.35
F13A_HUMAN F13A1 Coagulation factor XIII A chain 1.747e-46 0.40
NADE_BACAN nadE NH(3)-dependent NAD(+) synthetase 8.416e-44 0.35
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 3.82e-42 0.32
PSBA_SPIOL psbA Photosystem II protein D1 4.635e-42 0.36
EPHB_MYCTO Epoxide hydrolase B 1.187e-41 0.34
CAH7_MOUSE Ca7 Carbonic anhydrase 7 7.545e-40 0.32
CAHX_FLABI Carbonic anhydrase 7.545e-40 0.32
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 3.56e-37 0.29
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.073e-36 0.58
THRB_MOUSE F2 Prothrombin 8.333e-36 0.28
UREA_CANEN Urease 3.511e-35 0.37
VE1_HPV11 E1 Replication protein E1 1.406e-34 0.36
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 3.139e-33 0.34
CYNT_HELPY cynT Carbonic anhydrase 1.942e-31 0.42
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.314e-29 0.44
MYG_HUMAN MB Myoglobin 1.349e-29 0.58
MMP13_BOVIN MMP13 Collagenase 3 2.932e-29 0.35
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 5.659e-29 0.47
CAN_CANAL NCE103 Carbonic anhydrase 1.198e-28 0.36
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 1.042e-27 0.56
MYOC_HUMAN MYOC Myocilin 5.379e-25 0.31
MOGT2_MOUSE Mogat2 2-acylglycerol O-acyltransferase 2 4.212e-24 0.30
Q26964_TRYCR TCTS-154 Trans-sialidase 6.243e-24 0.29
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 1.137e-23 0.38
PLMN_MOUSE Plg Plasminogen 4.633e-23 0.28
TGM3L_HUMAN TGM6 Protein-glutamine gamma-glutamyltransferase 6 4.633e-23 0.28
UROK_RAT Plau Urokinase-type plasminogen activator 4.633e-23 0.28
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.327e-22 0.39
CAH4_HUMAN CA4 Carbonic anhydrase 4 8.978e-22 0.43
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.465e-21 0.31
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 4.358e-21 0.41
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.816e-20 0.33
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 7.518e-20 0.32
Q9HVB9_PSEAE Carbonic anhydrase 7.563e-20 0.32
Q5VLE3_EMEND rmtA RmtA 3.691e-19 0.30
AOC3_RAT Aoc3 Membrane primary amine oxidase 1.781e-18 0.34
TGM2_MOUSE Tgm2 Protein-glutamine gamma-glutamyltransferase 2 7.088e-18 0.28
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 8.866e-18 0.40
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.095e-17 0.48
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.48e-17 0.31
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.259e-17 0.42
Q9SPL6_CICIN PPX1 Protoporphyrinogen oxidase 5.295e-17 0.32
Q9XQA6_POAAN psbA Photosystem II protein D1 5.295e-17 0.32
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.11e-16 0.54
MMP12_HUMAN MMP12 Macrophage metalloelastase 1.11e-16 0.38
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 1.11e-16 0.44
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 2.22e-16 0.41
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 2.22e-16 0.46
B2V8E3_SULSY Carbonate dehydratase 3.331e-16 0.35
Q31FD6_HYDCU Carbonic anhydrase, alpha family 3.331e-16 0.35
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.665e-15 0.29
INSR_MOUSE Insr Insulin receptor 1.887e-15 0.31
A6YCJ1_9METZ Astrosclerin-3 2.22e-15 0.35
LIPL_RAT Lpl Lipoprotein lipase 2.442e-15 0.31
HELD_ECOLI helD DNA helicase IV 3.22e-15 0.29
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.087e-14 0.39
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.121e-14 0.39
MMP2_HUMAN MMP2 72 kDa type IV collagenase 2.431e-14 0.68
RORG_HUMAN RORC Nuclear receptor ROR-gamma 3.32e-14 0.41
CAH15_MOUSE Ca15 Carbonic anhydrase 15 4.319e-14 0.58
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 4.918e-14 0.39
ANDR_RAT Ar Androgen receptor 6.739e-14 0.37
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 7.494e-14 0.44
AOC3_HUMAN AOC3 Membrane primary amine oxidase 7.738e-14 0.34
NOX1_HUMAN NOX1 NADPH oxidase 1 1.193e-13 0.41
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.695e-13 0.32
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 4.253e-13 0.30
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 4.571e-13 0.68
UROK_MOUSE Plau Urokinase-type plasminogen activator 5.125e-13 0.28
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 5.806e-13 0.30
PRIO_SHEEP PRNP Major prion protein 6.761e-13 0.34
CAH_METTE Carbonic anhydrase 8.337e-13 0.35
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 1.741e-12 0.38
C0IX24_STYPI CA2 Carbonic anhydrase 2.523e-12 0.32
B5SU02_STYPI CA Alpha carbonic anhydrase 7.255e-12 0.32
Q2PCB5_DICLA ca Carbonic anhydrase 1.007e-11 0.32
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 1.059e-11 0.46
A6QR73_RAT Gpr39 G protein-coupled receptor 39 1.23e-11 0.28
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.782e-11 0.37
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 4.665e-11 0.32
NEP_RAT Mme Neprilysin 4.941e-11 0.38
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 5.463e-11 0.34
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 5.812e-11 0.60
GPR55_HUMAN GPR55 G-protein coupled receptor 55 6.045e-11 0.34
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 6.341e-11 0.31
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 6.381e-11 0.33
GUAD_HUMAN GDA Guanine deaminase 1.105e-10 0.29
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.317e-10 0.30
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.317e-10 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.61e-10 0.38
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 3.169e-10 0.41
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.923e-10 0.58
S100B_HUMAN S100B Protein S100-B 5.162e-10 0.29
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.036e-09 0.33
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.055e-09 0.38
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.713e-09 0.38
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.791e-09 0.29
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.173e-09 0.41
PLEC_HUMAN PLEC Plectin 4.055e-09 0.33
MMP13_HUMAN MMP13 Collagenase 3 5.096e-09 0.38
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 5.327e-09 0.58
MMP8_HUMAN MMP8 Neutrophil collagenase 6.626e-09 0.40
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 7.55e-09 0.31
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 7.572e-09 0.32
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 8.338e-09 0.30
Q76353_9HIV1 Integrase 8.715e-09 0.39
B4URF0_I33A0 Neuraminidase 9.102e-09 0.39
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 9.788e-09 0.32
KLK7_HUMAN KLK7 Kallikrein-7 1.359e-08 0.33
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.607e-08 0.30
CHS1_CANAX CHS1 Chitin synthase 1 1.881e-08 0.33
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.009e-08 0.35
SENP7_HUMAN SENP7 Sentrin-specific protease 7 2.518e-08 0.34
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.543e-08 0.29
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 2.586e-08 0.42
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.675e-08 0.38
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 2.994e-08 0.34
5NTD_RAT Nt5e 5'-nucleotidase 3.354e-08 0.49
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.828e-08 0.33
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 3.9e-08 0.31
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 4.857e-08 0.32
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 5.569e-08 0.42
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 6.325e-08 0.32
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 7.902e-08 0.41
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 8.154e-08 0.31
METC_ECOLI metC Cystathionine beta-lyase MetC 9.412e-08 0.30
CAH11_HUMAN CA11 Carbonic anhydrase-related protein 11 1.07e-07 0.32
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 2.05e-07 0.31
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 2.651e-07 0.30
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 3.014e-07 0.33
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 3.942e-07 0.41
CAH13_HUMAN CA13 Carbonic anhydrase 13 4.12e-07 0.41
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 4.177e-07 0.29
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 4.393e-07 0.34
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 4.707e-07 0.30
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.905e-07 0.29
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.284e-07 0.30
RARG_MOUSE Rarg Retinoic acid receptor gamma 5.74e-07 0.28
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 6.824e-07 0.38
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 7.672e-07 0.31
MMP1_HUMAN MMP1 Interstitial collagenase 7.692e-07 0.46
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 9.176e-07 0.33
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 9.176e-07 0.33
RARB_MOUSE Rarb Retinoic acid receptor beta 1.092e-06 0.28
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.453e-06 0.29
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.453e-06 0.29
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.453e-06 0.29
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.453e-06 0.29
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.453e-06 0.29
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.453e-06 0.29
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.453e-06 0.29
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.453e-06 0.29
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.453e-06 0.29
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.453e-06 0.29
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.453e-06 0.29
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.453e-06 0.29
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.453e-06 0.29
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.453e-06 0.29
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.453e-06 0.29
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.453e-06 0.29
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.453e-06 0.29
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.453e-06 0.29
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 1.594e-06 0.30
F261_HUMAN PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 1.732e-06 0.30
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 1.91e-06 0.30
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 2.133e-06 0.34
FEN1_HUMAN FEN1 Flap endonuclease 1 2.464e-06 0.33
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.521e-06 0.29
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.849e-06 0.29
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.849e-06 0.29
5NTD_HUMAN NT5E 5'-nucleotidase 3.77e-06 0.29
Q932Y6_PSEAI bla(tem-2) Beta-lactamase 3.86e-06 0.35
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 4.13e-06 0.38
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 4.647e-06 0.33
RARA_MOUSE Rara Retinoic acid receptor alpha 5.252e-06 0.28
ISPT_STRPN uppS Isoprenyl transferase 7.045e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 8.279e-06 0.28
MITF_HUMAN MITF Microphthalmia-associated transcription factor 9.894e-06 0.39

Sulfadoxine

TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 1.251e-89 0.38
EDNRA_PIG EDNRA Endothelin-1 receptor 3.042e-72 0.47
CCR4_CANLF CCR4 C-C chemokine receptor type 4 1.694e-56 0.37
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 6.437e-42 0.48
Q56D22_MACMU HSD11B1 Hydroxysteroid 11-beta dehydrogenase 1 4.749e-37 0.29
EDNRB_HUMAN EDNRB Endothelin receptor type B 7.958e-34 0.44
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 4.137e-29 0.28
EDNRA_HUMAN EDNRA Endothelin-1 receptor 9.201e-25 0.43
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.077e-24 0.40
SC5A7_RAT Slc5a7 High affinity choline transporter 1 7.498e-24 0.29
BRPF3_HUMAN BRPF3 Bromodomain and PHD finger-containing protein 3 8.214e-24 0.30
CYNT_HELPY cynT Carbonic anhydrase 1.068e-23 0.37
BRD4_MOUSE Brd4 Bromodomain-containing protein 4 4.185e-23 0.28
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 6.659e-23 0.37
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 9.648e-21 0.41
EDNRA_RAT Ednra Endothelin-1 receptor 2.551e-20 0.46
ARY2_MOUSE Nat2 Arylamine N-acetyltransferase 2 6.181e-20 0.32
Q5XX84_CANLF HSD11B1 11-beta-hydroxysteroid dehydrogenase type 1 1.753e-18 0.29
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 2.806e-18 0.31
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 6.649e-18 0.40
FFAR4_RAT Ffar4 Free fatty acid receptor 4 8.756e-18 0.34
ARY1_HUMAN NAT1 Arylamine N-acetyltransferase 1 1.422e-17 0.32
C0IX24_STYPI CA2 Carbonic anhydrase 1.494e-17 0.37
B2V8E3_SULSY Carbonate dehydratase 1.11e-16 0.37
B5SU02_STYPI CA Alpha carbonic anhydrase 1.11e-16 0.37
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.11e-16 0.37
A6YCJ1_9METZ Astrosclerin-3 5.551e-16 0.37
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 8.882e-16 0.37
CAN_YEAST NCE103 Carbonic anhydrase 4.752e-14 0.37
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.537e-13 0.42
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.062e-13 0.40
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 3.249e-13 0.30
KMO_RAT Kmo Kynurenine 3-monooxygenase 6.595e-13 0.33
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 1.143e-12 0.28
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 2.07e-12 0.34
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.867e-12 0.39
CAH_METTE Carbonic anhydrase 3.351e-12 0.32
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 1.15e-11 0.31
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.246e-11 0.37
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 4.275e-11 0.30
Q81VW8_BACAN folP Dihydropteroate synthase 8.191e-11 0.29
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.343e-11 0.32
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 2.363e-10 0.38
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 2.921e-10 0.35
Q6FTL6_CANGA NCE103 Carbonic anhydrase 9.198e-10 0.37
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.109e-09 0.37
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.306e-09 0.32
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.642e-09 0.30
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 2.211e-09 0.33
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 2.251e-09 0.34
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 5.075e-09 0.28
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.008e-08 0.30
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.028e-08 0.37
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.353e-08 0.33
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.093e-08 0.38
BRPF1_HUMAN BRPF1 Peregrin 2.919e-08 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.719e-07 0.42
METC_ECOLI metC Cystathionine beta-lyase MetC 1.995e-07 0.29
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 2.15e-07 0.28
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 3.664e-07 0.32
CAN_CANAL NCE103 Carbonic anhydrase 4.496e-07 0.37
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.493e-06 0.37
5NTD_HUMAN NT5E 5'-nucleotidase 1.653e-06 0.31
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.841e-06 0.28
EDNRB_RAT Ednrb Endothelin receptor type B 4e-06 0.32
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 5.467e-06 0.34
CAH13_HUMAN CA13 Carbonic anhydrase 13 6.917e-06 0.40
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 8.543e-06 0.29

Atovaquone

Q9MYJ9_RABIT CCR1 Chemokine receptor 2.422e-46 0.37
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 4.071e-39 0.37
TBA_TRYCR Tubulin alpha chain 3.98e-36 0.30
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 5.481e-22 0.35
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 4.368e-18 0.30
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 2.22e-15 0.35
CBPB_HELZE CPB Carboxypeptidase B 1.884e-13 0.29
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 2.067e-12 0.34
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.075e-11 0.34
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.266e-10 0.35
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 9.443e-10 0.36
Q9WTR4_RAT Slc6a2 Transporter 2.336e-09 0.33
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 3.259e-09 0.35
BIRC5_HUMAN BIRC5 Baculoviral IAP repeat-containing protein 5 1.292e-08 0.29
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 2.355e-08 0.33
SQHC_ALIAD shc Squalene--hopene cyclase 2.835e-08 0.30
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.519e-08 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 8.153e-08 0.33
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 8.23e-08 0.31
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.526e-07 0.35
EST2_HUMAN CES2 Cocaine esterase 9.025e-07 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.056e-06 0.35
SC6A4_MACMU SLC6A4 Sodium-dependent serotonin transporter 1.137e-06 0.28
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.011e-06 0.33
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.049e-06 0.29
EST1_HUMAN CES1 Liver carboxylesterase 1 2.327e-06 0.33
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 2.488e-06 0.30
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.845e-06 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.989e-06 0.32
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 4.125e-06 0.33
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 5.084e-06 0.32
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 5.416e-06 0.35

Artefenomel

ESR2_HUMAN ESR2 Estrogen receptor beta 1.364e-45 0.38
ESR1_HUMAN ESR1 Estrogen receptor 6.515e-43 0.38
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.377e-36 0.41
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.363e-29 0.38
HRH3_MOUSE Hrh3 Histamine H3 receptor 1.006e-26 0.44
HRH3_HUMAN HRH3 Histamine H3 receptor 4.331e-20 0.48
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.22e-16 0.33
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 4.104e-12 0.31
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 8.493e-12 0.38
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 8.915e-11 0.39
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 9.558e-11 0.34
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.396e-10 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 5.525e-08 0.38
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 7.608e-08 0.34
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 2.252e-07 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.502e-07 0.39
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 1.107e-06 0.34
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1.186e-06 0.34
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 2.704e-06 0.35

Chlorproguanil

MED15_CANGA GAL11 Mediator of RNA polymerase II transcription subunit 15 1.968e-44 0.35
KCNB2_HUMAN KCNB2 Potassium voltage-gated channel subfamily B member 2 2.89e-41 0.33
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 7.345e-41 0.32
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 1.188e-39 0.32
NADE_BACAN nadE NH(3)-dependent NAD(+) synthetase 5.06e-39 0.31
NMDZ1_MOUSE Grin1 Glutamate receptor ionotropic, NMDA 1 7.62e-36 0.28
Q9I8A2_CHICK VATB Vacuolar proton pump subunit B 4.165e-31 0.31
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.853e-30 0.35
EPHB_MYCTO Epoxide hydrolase B 8.534e-26 0.41
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.429e-23 0.42
Q9SPL6_CICIN PPX1 Protoporphyrinogen oxidase 1.012e-22 0.44
Q9XQA6_POAAN psbA Photosystem II protein D1 1.012e-22 0.44
BLM_HUMAN BLM Bloom syndrome protein 1.435e-20 0.32
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 2.665e-15 0.29
PSBA_MARPO psbA Photosystem II protein D1 1.14e-13 0.44
CCR2_RAT Ccr2 C-C chemokine receptor type 2 1.463e-13 0.33
ENV_HV1Y2 env Envelope glycoprotein gp160 1.938e-13 0.30
AMPN_PIG ANPEP Aminopeptidase N 1.503e-12 0.42
PRIM_HHV11 DNA primase 4.196e-11 0.30
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 5.846e-11 0.32
UT1_RAT Slc14a1 Urea transporter 1 1.415e-10 0.28
S100B_HUMAN S100B Protein S100-B 3.105e-10 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.404e-10 0.34
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 6.829e-10 0.34
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 8.352e-09 0.33
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 2.928e-08 0.31
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.985e-08 0.29
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 5.165e-08 0.31
CBPB1_PIG CPB1 Carboxypeptidase B 6.091e-08 0.33
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 7.361e-08 0.31
KMO_RAT Kmo Kynurenine 3-monooxygenase 8.467e-08 0.32
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 1.086e-07 0.36
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 1.279e-07 0.33
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.612e-07 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.935e-07 0.51
AOFB_RAT Maob Amine oxidase [flavin-containing] B 3.647e-07 0.35
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 6.148e-07 0.28
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 6.557e-07 0.31
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.183e-06 0.29
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.648e-06 0.30
TOP3_BACSU topB DNA topoisomerase 3 2.064e-06 0.30
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 3.744e-06 0.42
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 3.987e-06 0.33
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 4.123e-06 0.33
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 6.137e-06 0.32
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 6.973e-06 0.30
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 8.557e-06 0.36

Proguanil

SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.275e-38 0.50
Q76270_9HIV1 HIV1 ENV GP41 6.694e-38 0.30
O69638_MYCTO Hydrolase, alpha/beta hydrolase fold family 9.362e-36 0.28
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 8.709e-24 0.33
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 4.755e-23 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 7.097e-22 0.41
PSBA_MARPO psbA Photosystem II protein D1 1.878e-21 0.39
EPHB_MYCTO Epoxide hydrolase B 2.157e-21 0.34
S100B_HUMAN S100B Protein S100-B 6.412e-19 0.29
PSBA_SPIOL psbA Photosystem II protein D1 1.11e-16 0.39
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.11e-16 0.33
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 8.882e-16 0.33
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 9.548e-15 0.33
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.154e-13 0.39
H9CNL0_SPOEX Ryanodien receptor 1.647e-10 0.28
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.991e-10 0.35
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.351e-10 0.33
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 2.69e-10 0.45
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 3.073e-10 0.35
Q6DMN0_TOXGO CPL Cathepsin L 5.162e-10 0.29
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 7.415e-10 0.35
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 7.957e-10 0.45
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 1.729e-09 0.35
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 2.126e-09 0.33
TAAR1_RAT Taar1 Trace amine-associated receptor 1 4.512e-09 0.36
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.514e-08 0.33
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.303e-08 0.40
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 4.269e-08 0.34
LIPL_RAT Lpl Lipoprotein lipase 5.111e-08 0.30
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 6.354e-08 0.33
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 7.803e-08 0.55
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 8.839e-08 0.29
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.31e-07 0.34
ACRO_HUMAN ACR Acrosin 3.024e-07 0.34
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.083e-07 0.33
AMPN_PIG ANPEP Aminopeptidase N 3.253e-07 0.32
FA11_HUMAN F11 Coagulation factor XI 3.304e-07 0.31
Q25615_ONCVO Chitinase 3.706e-07 0.29
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 5.622e-07 0.28
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 1.433e-06 0.45
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 2.252e-06 0.30
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.521e-06 0.29
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 3.572e-06 0.30
CAN1_RAT Capn1 Calpain-1 catalytic subunit 5.734e-06 0.29
Q03732_HBV HBcAg Capsid protein 7.679e-06 0.30
PAO1_MAIZE MPAO1 Polyamine oxidase 1 8.307e-06 0.31

Artemether

Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 3.415e-30 0.47

Artemotil

Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 6.74e-30 0.46
GLI1_MOUSE Gli1 Zinc finger protein GLI1 7.672e-06 0.60

Artesunate

Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 3.931e-27 0.42
GLI1_MOUSE Gli1 Zinc finger protein GLI1 3.039e-07 0.73

Artenimol

Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 4.578e-26 0.40

Tafenoquine

PERL_BOVIN LPO Lactoperoxidase 4.438e-13 0.42
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.31e-06 0.28

Tetrandrine

PERL_BOVIN LPO Lactoperoxidase 4.438e-13 0.42
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.31e-06 0.28

JPC-3210

GLR_HUMAN GCGR Glucagon receptor 4.927e-10 0.30
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.715e-06 0.30
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 2.585e-06 0.30
STIM1_HUMAN STIM1 Stromal interaction molecule 1 4.686e-06 0.30