Results of Job: search_57b2e3fe-a4e5-4dd7-925a-caf514e551af

Query Target Key Target Name Description P-Value MaxTC

compound_1

KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 5.796e-235 0.87
AURKA_HUMAN AURKA Aurora kinase A 2.466e-199 0.87
AURKB_HUMAN AURKB Aurora kinase B 5.683e-109 0.65
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 2.687e-76 0.38
EGFR_HUMAN EGFR Epidermal growth factor receptor 9.198e-70 0.44
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.211e-67 0.34
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.49e-63 0.47
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.944e-46 0.38
NNMT_MOUSE Nnmt Nicotinamide N-methyltransferase 1.841e-40 0.32
EGFR_MOUSE Egfr Epidermal growth factor receptor 2.765e-40 0.31
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 3.173e-39 0.35
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 3.56e-37 0.29
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 3.584e-32 0.43
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.138e-31 0.38
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 7.072e-31 0.43
PRIO_SHEEP PRNP Major prion protein 1.342e-30 0.36
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 3.8e-28 0.35
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.998e-26 0.44
CTNB1_HUMAN CTNNB1 Catenin beta-1 5.865e-26 0.35
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 4.644e-23 0.36
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.8e-23 0.34
AUKBA_XENLA aurkb-a Aurora kinase B-A 6.194e-23 0.37
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 8.182e-23 0.37
RS27_HUMAN RPS27 40S ribosomal protein S27 3.663e-22 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 9.741e-22 0.39
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.101e-20 0.32
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.211e-20 0.43
SHH_MOUSE Shh Sonic hedgehog protein 8.442e-20 0.33
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.13e-19 0.34
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 2.858e-19 0.39
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.86e-19 0.30
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 5.859e-19 0.36
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.928e-18 0.36
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.482e-17 0.29
UROK_HUMAN PLAU Urokinase-type plasminogen activator 4.584e-17 0.39
TPOR_HUMAN MPL Thrombopoietin receptor 3.331e-16 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 4.441e-16 0.31
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 1.554e-15 0.32
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 2.998e-15 0.34
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.441e-15 0.36
AHK3_ARATH AHK3 Histidine kinase 3 4.441e-15 0.29
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.399e-14 0.39
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 1.421e-14 0.33
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.665e-14 0.36
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 3.02e-14 0.50
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 8.36e-14 0.28
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 9.504e-14 0.30
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 4.328e-13 0.35
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 4.431e-13 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 9.754e-13 0.37
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.038e-12 0.43
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 2.757e-12 0.30
CCNA1_HUMAN CCNA1 Cyclin-A1 4.187e-12 0.31
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.533e-12 0.31
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 9.715e-12 0.36
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 5.424e-11 0.43
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 5.659e-11 0.29
CCNK_HUMAN CCNK Cyclin-K 9.585e-11 0.29
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.798e-10 0.41
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 1.835e-10 0.31
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 2.51e-10 0.31
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 2.525e-10 0.36
HDAC1_HUMAN HDAC1 Histone deacetylase 1 6.884e-10 0.43
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.012e-09 0.28
SMO_HUMAN SMO Smoothened homolog 1.128e-09 0.36
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.16e-09 0.32
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.165e-09 0.39
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.263e-09 0.31
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 2.492e-09 0.31
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 3.647e-09 0.43
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 5.367e-09 0.30
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 8.05e-09 0.31
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 9.136e-09 0.43
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.346e-08 0.36
Q76129_9HIV1 gag Structural capsid protein 1.389e-08 0.29
LIMK1_HUMAN LIMK1 LIM domain kinase 1 1.721e-08 0.37
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.766e-08 0.43
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.771e-08 0.43
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 2.003e-08 0.61
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.092e-08 0.37
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 2.409e-08 0.34
STXA_SHIDY stxA Shiga toxin subunit A 2.572e-08 0.29
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 2.888e-08 0.37
KLK1_HUMAN KLK1 Kallikrein-1 3.423e-08 0.34
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 4.633e-08 0.30
PLMN_HUMAN PLG Plasminogen 5.387e-08 0.38
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 5.81e-08 0.44
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 8.115e-08 0.37
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 9.558e-08 0.32
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 9.843e-08 0.30
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.106e-07 0.30
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.717e-07 0.31
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.717e-07 0.31
IL6_HUMAN IL6 Interleukin-6 2.362e-07 0.29
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 2.38e-07 0.30
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 2.49e-07 0.39
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 2.589e-07 0.31
CYNT_HELPY cynT Carbonic anhydrase 3.254e-07 0.31
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 3.258e-07 0.31
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 3.272e-07 0.33
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.625e-07 0.44
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 3.829e-07 0.43
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.518e-07 0.30
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 4.871e-07 0.37
HDAC3_HUMAN HDAC3 Histone deacetylase 3 5.993e-07 0.43
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 6.128e-07 0.35
GYRB_MYCSM gyrB DNA gyrase subunit B 7.005e-07 0.32
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 7.045e-07 0.29
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 7.088e-07 0.35
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 7.411e-07 0.35
LCK_HUMAN LCK Tyrosine-protein kinase Lck 9.577e-07 0.37
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.219e-06 0.34
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 1.287e-06 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.404e-06 0.30
PAG_BACAN pagA Protective antigen 1.437e-06 0.40
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.507e-06 0.30
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.647e-06 0.33
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.802e-06 0.32
LUCI_AQULA Luciferin 4-monooxygenase 1.971e-06 0.32
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.488e-06 0.30
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 2.577e-06 0.43
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.587e-06 0.29
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 2.598e-06 0.33
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 3.292e-06 0.33
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 4.496e-06 0.37
MINK1_HUMAN MINK1 Misshapen-like kinase 1 4.82e-06 0.33
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 4.958e-06 0.35
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.062e-06 0.37
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 5.567e-06 0.28
PLEC_HUMAN PLEC Plectin 6.091e-06 0.30
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 6.352e-06 0.42
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 7.967e-06 0.33
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 9.749e-06 0.43