Results of Job: search_59558591-818b-4c36-9a62-363e16413ab1

Query Target Key Target Name Description P-Value MaxTC

compound_1

EGFR_HUMAN EGFR Epidermal growth factor receptor 0 0.89
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.318e-299 0.69
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 2.278e-256 0.48
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 6.788e-207 0.48
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 5.245e-170 0.67
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.337e-118 0.67
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 9.587e-69 0.55
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 6.33e-61 0.39
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 5.485e-59 0.38
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 8.365e-59 0.47
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 1.311e-55 0.43
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 2.027e-53 0.57
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.336e-52 0.42
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 1.985e-51 0.67
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 3.73e-45 0.47
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.147e-44 0.45
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.031e-44 0.43
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 4.091e-41 0.33
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.52e-40 0.38
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 5.692e-38 0.39
PDE5A_BOVIN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 4.133e-36 0.38
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 5.757e-32 0.67
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 7.143e-32 0.67
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 1.317e-30 0.36
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 7.02e-30 0.67
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 5.434e-29 0.67
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 1.729e-28 0.29
EGFR_MOUSE Egfr Epidermal growth factor receptor 7.555e-28 0.33
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.462e-27 0.67
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 3.093e-27 0.38
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 4.833e-27 0.39
ATM_HUMAN ATM Serine-protein kinase ATM 6.442e-27 0.32
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 1.294e-26 0.67
CTRO_HUMAN CIT Citron Rho-interacting kinase 7.107e-26 0.59
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.58e-25 0.59
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 6.03e-25 0.47
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.124e-24 0.67
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.204e-24 0.59
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.643e-24 0.59
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 2.121e-24 0.67
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 5.464e-24 0.67
TXK_HUMAN TXK Tyrosine-protein kinase TXK 6.051e-24 0.67
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 7.305e-24 0.57
AURKA_HUMAN AURKA Aurora kinase A 1.466e-23 0.52
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.906e-23 0.67
AUKBA_XENLA aurkb-a Aurora kinase B-A 3.536e-23 0.37
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 8.713e-23 0.67
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.842e-22 0.67
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 6.152e-22 0.67
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 9.067e-22 0.42
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.119e-21 0.47
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.223e-21 0.43
STK3_MOUSE Stk3 Serine/threonine-protein kinase 3 5.434e-21 0.47
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 9.542e-21 0.35
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.312e-20 0.47
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 2.935e-20 0.67
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 9.42e-20 0.47
AURKB_HUMAN AURKB Aurora kinase B 1.12e-19 0.44
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 1.841e-19 0.67
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.737e-19 0.67
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 4.039e-19 0.40
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 4.865e-19 0.34
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 8.299e-19 0.67
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 9.004e-19 0.36
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 1.011e-18 0.67
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.151e-18 0.67
GAK_HUMAN GAK Cyclin-G-associated kinase 1.163e-18 0.67
LUCI_RENRE Coelenterazine h 2-monooxygenase 1.348e-18 0.35
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 1.864e-18 0.39
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.094e-18 0.59
DMPK_HUMAN DMPK Myotonin-protein kinase 3.749e-18 0.47
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 4.917e-18 0.67
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 1.045e-17 0.47
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1.95e-17 0.67
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 4.552e-17 0.67
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.11e-16 0.67
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 1.11e-16 0.67
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 1.11e-16 0.67
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 3.331e-16 0.33
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 4.441e-16 0.40
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.331e-15 0.33
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 4.996e-15 0.67
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 1.577e-14 0.67
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.965e-14 0.67
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.121e-14 0.47
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 3.175e-14 0.47
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 3.608e-14 0.67
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 1.336e-13 0.47
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 2.325e-13 0.67
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 3.056e-13 0.67
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 3.072e-13 0.67
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 3.306e-13 0.34
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 4.922e-13 0.67
INSR_HUMAN INSR Insulin receptor 5.553e-13 0.67
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 6.588e-13 0.28
INSRR_HUMAN INSRR Insulin receptor-related protein 8.397e-13 0.67
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.574e-12 0.33
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.613e-12 0.47
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 2.121e-12 0.67
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 2.71e-12 0.59
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.034e-12 0.59
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 3.315e-12 0.59
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 4.981e-12 0.67
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 5.411e-12 0.33
LCK_HUMAN LCK Tyrosine-protein kinase Lck 6.052e-12 0.67
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 6.378e-12 0.41
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 7.232e-12 0.43
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 9.362e-12 0.47
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.462e-11 0.47
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.827e-11 0.51
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 3.395e-11 0.67
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 3.658e-11 0.47
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 6.472e-11 0.67
HDAC3_HUMAN HDAC3 Histone deacetylase 3 7.282e-11 0.42
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.036e-10 0.67
CYSP_PLAFA Trophozoite cysteine proteinase 1.073e-10 0.30
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.222e-10 0.67
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 1.235e-10 0.31
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.726e-10 0.31
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.755e-10 0.33
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 1.956e-10 0.67
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.124e-10 0.67
Q9Z1J7_RAT Slc1a5 Amino acid transporter 3.705e-10 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 3.815e-10 0.67
BKRB2_HUMAN BDKRB2 B2 bradykinin receptor 7.791e-10 0.32
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 1.347e-09 0.32
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.569e-09 0.33
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 2.641e-09 0.41
HDAC6_HUMAN HDAC6 Histone deacetylase 6 3.012e-09 0.42
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 3.131e-09 0.59
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 4.132e-09 0.47
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 4.36e-09 0.67
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 5.495e-09 0.67
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 6.002e-09 0.31
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 6.293e-09 0.67
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 6.293e-09 0.67
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 7.086e-09 0.47
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 7.086e-09 0.47
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.093e-08 0.29
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.269e-08 0.42
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.302e-08 0.67
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.857e-08 0.36
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 2.245e-08 0.47
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.596e-08 0.30
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 3.351e-08 0.67
CATL2_HUMAN CTSV Cathepsin L2 3.979e-08 0.30
VP16_HHV11 Tegument protein VP16 4.422e-08 0.31
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 5.018e-08 0.67
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 5.326e-08 0.38
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 6.061e-08 0.47
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 7.7e-08 0.67
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 7.747e-08 0.67
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 9.329e-08 0.67
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.104e-07 0.67
FRK_HUMAN FRK Tyrosine-protein kinase FRK 1.116e-07 0.59
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 1.168e-07 0.30
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 1.168e-07 0.30
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 1.316e-07 0.67
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1.334e-07 0.59
SHH_MOUSE Shh Sonic hedgehog protein 1.929e-07 0.32
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 2.051e-07 0.67
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 2.365e-07 0.67
MET_HUMAN MET Hepatocyte growth factor receptor 2.465e-07 0.67
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 2.466e-07 0.36
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 2.468e-07 0.30
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 2.507e-07 0.30
HCK_HUMAN HCK Tyrosine-protein kinase HCK 2.833e-07 0.67
SMO_HUMAN SMO Smoothened homolog 3.827e-07 0.34
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 3.846e-07 0.45
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 4.948e-07 0.30
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 5.443e-07 0.33
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 5.529e-07 0.32
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.011e-06 0.28
E2AK2_HUMAN EIF2AK2 Interferon-induced, double-stranded RNA-activated protein kinase 1.105e-06 0.47
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.61e-06 0.59
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 1.791e-06 0.67
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 1.874e-06 0.47
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 1.885e-06 0.47
RON_HUMAN MST1R Macrophage-stimulating protein receptor 1.989e-06 0.67
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 2.007e-06 0.67
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 2.265e-06 0.67
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 2.286e-06 0.67
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 2.32e-06 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.417e-06 0.33
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 3.119e-06 0.29
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 3.46e-06 0.67
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 3.608e-06 0.36
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 4.295e-06 0.67
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 5.176e-06 0.37
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 6.068e-06 0.67
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 6.241e-06 0.30
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 6.423e-06 0.67
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 6.602e-06 0.30
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 7.056e-06 0.67
FER_HUMAN FER Tyrosine-protein kinase Fer 7.398e-06 0.67
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 8.068e-06 0.36
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 8.482e-06 0.33
BKRB2_CAVPO BDKRB2 B2 bradykinin receptor 9.323e-06 0.32
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 9.591e-06 0.67
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 9.774e-06 0.67