Results of Job: search_5d2e177b-d71d-4342-a1ea-321ca1dedde7

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 3.894e-185 0.64
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 3.872e-99 0.48
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 5.313e-92 0.39
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.143e-72 0.38
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.621e-71 0.39
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.45e-68 0.40
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 4.791e-66 0.37
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.473e-63 0.39
Q8IL11_PLAF7 M17 leucyl aminopeptidase 1.388e-54 0.45
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 8.606e-52 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.638e-46 0.44
O31272_9GAMM imiS Beta-lactamase 2.235e-46 0.35
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 2.001e-45 0.35
SHH_MOUSE Shh Sonic hedgehog protein 3.991e-45 0.37
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.843e-44 0.48
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.5e-43 0.45
TLR4_MOUSE Tlr4 Toll-like receptor 4 4.118e-42 0.39
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.034e-41 0.39
PRIO_HUMAN PRNP Major prion protein 1.557e-39 0.37
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.001e-38 0.41
MET_HUMAN MET Hepatocyte growth factor receptor 2.191e-37 0.41
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.296e-36 0.40
RCOR3_HUMAN RCOR3 REST corepressor 3 7.62e-36 0.28
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 1.157e-35 0.29
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 1.735e-33 0.34
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 9.409e-32 0.33
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.035e-29 0.32
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 2.203e-29 0.36
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 2.716e-29 0.41
KC1D_RAT Csnk1d Casein kinase I isoform delta 1.885e-26 0.42
Q38C41_TRYB2 Phosphotransferase 1.937e-26 0.35
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 7.638e-26 0.32
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 8.211e-26 0.34
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 1.771e-24 0.36
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.274e-24 0.40
ATM_HUMAN ATM Serine-protein kinase ATM 4.165e-24 0.31
TLR4_HUMAN TLR4 Toll-like receptor 4 4.906e-24 0.39
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 5.448e-24 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.235e-23 0.35
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.527e-23 0.41
PANK1_HUMAN PANK1 Pantothenate kinase 1 2.104e-23 0.30
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 2.545e-23 0.50
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.043e-22 0.48
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 4.306e-22 0.50
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.245e-21 0.34
TSHR_HUMAN TSHR Thyrotropin receptor 3.708e-21 0.34
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 1.309e-20 0.43
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.768e-20 0.31
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 1.771e-20 0.47
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 6.91e-20 0.33
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.353e-19 0.35
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.901e-19 0.39
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 4.611e-19 0.33
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 8.598e-19 0.46
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 2.922e-18 0.37
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 4.879e-18 0.29
Q7K6A1_PLAF7 Histone deacetylase 6.785e-18 0.28
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.053e-17 0.35
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.819e-17 0.36
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.11e-16 0.38
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.11e-16 0.49
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.11e-16 0.30
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.11e-16 0.33
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.22e-16 0.36
AURKA_HUMAN AURKA Aurora kinase A 3.331e-16 0.38
ACES_ELEEL ache Acetylcholinesterase 2.776e-15 0.34
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 4.774e-15 0.42
PA21B_HUMAN PLA2G1B Phospholipase A2 4.996e-15 0.46
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 2.021e-14 0.36
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 2.953e-14 0.36
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 4.596e-14 0.39
Q9NBA7_PLAFA Cysteine protease falcipain-3 7.816e-14 0.38
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 8.338e-14 0.36
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 8.737e-14 0.38
CASB_RAT Csn2 Beta-casein 1.581e-13 0.29
CCKAR_RAT Cckar Cholecystokinin receptor type A 1.614e-13 0.43
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 2.01e-13 0.29
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.27e-13 0.32
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.816e-13 0.48
MET_MOUSE Met Hepatocyte growth factor receptor 3.922e-13 0.29
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 5.714e-13 0.34
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 7.17e-13 0.38
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 7.691e-13 0.36
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.283e-12 0.37
PRIO_SHEEP PRNP Major prion protein 2.982e-12 0.31
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 5.798e-12 0.36
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.265e-11 0.49
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 1.397e-11 0.31
RECA_MYCTU recA Protein RecA 1.888e-11 0.41
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.599e-11 0.36
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.624e-11 0.39
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 3.173e-11 0.32
BGLR_HUMAN GUSB Beta-glucuronidase 3.319e-11 0.30
MEP50_HUMAN WDR77 Methylosome protein 50 3.796e-11 0.35
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 4.936e-11 0.35
AURKB_HUMAN AURKB Aurora kinase B 5.888e-11 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 9.234e-11 0.36
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 1.802e-10 0.30
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 2.331e-10 0.30
TIE2_HUMAN TEK Angiopoietin-1 receptor 3.175e-10 0.36
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.082e-10 0.36
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 5.501e-10 0.36
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.993e-10 0.34
HSF1_MOUSE Hsf1 Heat shock factor protein 1 6.245e-10 0.45
XBP1_HUMAN XBP1 X-box-binding protein 1 6.403e-10 0.40
S100B_HUMAN S100B Protein S100-B 7.541e-10 0.29
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 7.984e-10 0.41
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 1.078e-09 0.37
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 1.246e-09 0.36
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 1.297e-09 0.33
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.403e-09 0.31
S12A5_HUMAN SLC12A5 Solute carrier family 12 member 5 1.757e-09 0.28
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.971e-09 0.31
IBP5_HUMAN IGFBP5 Insulin-like growth factor-binding protein 5 2.15e-09 0.29
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.743e-09 0.36
HDAC8_HUMAN HDAC8 Histone deacetylase 8 3.31e-09 0.36
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 3.532e-09 0.33
KLK7_HUMAN KLK7 Kallikrein-7 4.322e-09 0.39
DNAB_MYCTU dnaB Replicative DNA helicase 4.618e-09 0.41
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 4.659e-09 0.31
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 5.573e-09 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.003e-09 0.41
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 1.285e-08 0.35
CHLE_HORSE BCHE Cholinesterase 1.333e-08 0.34
TERT_HUMAN TERT Telomerase reverse transcriptase 1.369e-08 0.32
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.528e-08 0.38
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.701e-08 0.34
CHLE_HUMAN BCHE Cholinesterase 1.809e-08 0.34
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 2.534e-08 0.29
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 2.907e-08 0.35
AA3R_HUMAN ADORA3 Adenosine receptor A3 4.208e-08 0.36
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.589e-08 0.28
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 5.566e-08 0.40
A5H660_SCHMA HDAC8 Histone deacetylase 8 5.746e-08 0.29
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 5.894e-08 0.33
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 6.881e-08 0.39
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 7.013e-08 0.45
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 7.377e-08 0.31
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 9.036e-08 0.30
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 9.145e-08 0.30
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 1.504e-07 0.39
TNFA_HUMAN TNF Tumor necrosis factor 1.855e-07 0.38
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.967e-07 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 2.637e-07 0.31
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.944e-07 0.47
DYR_HUMAN DHFR Dihydrofolate reductase 3.19e-07 0.36
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 4.27e-07 0.39
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 4.452e-07 0.33
O97467_PLAFA ht1 Hexose transporter 1 5.111e-07 0.32
KLF5_HUMAN KLF5 Krueppel-like factor 5 5.112e-07 0.30
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 5.517e-07 0.37
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 5.57e-07 0.30
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 5.688e-07 0.33
O61059_LEIME LmGT2 Glucose transporter 5.723e-07 0.32
IDE_HUMAN IDE Insulin-degrading enzyme 5.733e-07 0.34
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 6.009e-07 0.31
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 6.187e-07 0.28
A3KMY8_BOVIN GUSB Beta-glucuronidase 7.042e-07 0.30
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 7.878e-07 0.38
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 7.988e-07 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 8.288e-07 0.32
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 1.032e-06 0.28
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.108e-06 0.45
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.132e-06 0.33
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 1.181e-06 0.33
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 1.203e-06 0.39
GPR55_HUMAN GPR55 G-protein coupled receptor 55 1.341e-06 0.42
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1.502e-06 0.31
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.52e-06 0.37
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.609e-06 0.32
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.935e-06 0.36
RON_HUMAN MST1R Macrophage-stimulating protein receptor 2.368e-06 0.36
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 2.425e-06 0.40
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.488e-06 0.30
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.631e-06 0.32
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.696e-06 0.36
CBPB1_HUMAN CPB1 Carboxypeptidase B 3.131e-06 0.29
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 3.33e-06 0.38
DPOL_VACCW POL DNA polymerase 3.36e-06 0.30
STRP_STRP1 ska Streptokinase A 3.362e-06 0.44
KLK5_HUMAN KLK5 Kallikrein-5 3.409e-06 0.28
ACES_HUMAN ACHE Acetylcholinesterase 3.544e-06 0.34
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.769e-06 0.36
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 4.188e-06 0.29
KHK_HUMAN KHK Ketohexokinase 4.684e-06 0.31
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.087e-06 0.32
TRYP_PIG Trypsin 5.155e-06 0.38
HPSE_HUMAN HPSE Heparanase 5.792e-06 0.31
COT2_HUMAN NR2F2 COUP transcription factor 2 6.008e-06 0.35
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 6.155e-06 0.44
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 6.869e-06 0.34
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 7.488e-06 0.32
A4_HUMAN APP Amyloid-beta precursor protein 7.943e-06 0.33
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 8.833e-06 0.28
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 9.838e-06 0.32