Results of Job: search_5eb84eb5-58c9-403a-8231-627dfa78c342

Query Target Key Target Name Description P-Value MaxTC

compound_1

EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.481e-171 0.40
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 8.855e-144 0.44
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.087e-113 0.48
DYR_BOVIN DHFR Dihydrofolate reductase 1.986e-111 0.44
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.134e-77 0.45
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.937e-74 0.49
MET_HUMAN MET Hepatocyte growth factor receptor 8.156e-73 0.39
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 5.25e-69 0.48
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.641e-66 0.48
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.897e-62 0.36
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.095e-60 0.44
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 2.003e-52 0.42
P2RX3_HUMAN P2RX3 P2X purinoceptor 3 3.564e-49 0.33
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 8.966e-49 0.31
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 7.213e-46 0.32
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.472e-44 0.39
Q8IL11_PLAF7 M17 leucyl aminopeptidase 7.433e-44 0.46
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 6.529e-39 0.40
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 2.001e-35 0.37
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 7.268e-35 0.44
FA11_HUMAN F11 Coagulation factor XI 1.065e-34 0.35
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 6.999e-34 0.37
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.754e-29 0.35
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 2.07e-29 0.39
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 1.371e-27 0.37
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.587e-27 0.39
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.664e-25 0.45
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 3.139e-25 0.31
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.177e-25 0.34
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 4.746e-25 0.35
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 6.703e-25 0.36
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.412e-24 0.36
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 2.529e-24 0.42
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 6.786e-24 0.34
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 2.208e-23 0.35
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.447e-22 0.36
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 2.457e-22 0.36
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.721e-22 0.44
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 2.926e-21 0.39
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.458e-19 0.34
EPHB_MYCTO Epoxide hydrolase B 1.039e-18 0.30
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.51e-18 0.30
AUKBA_XENLA aurkb-a Aurora kinase B-A 3.952e-18 0.29
C3SLB7_ECOLX glmU Bifunctional protein GlmU 7.138e-18 0.33
O31272_9GAMM imiS Beta-lactamase 7.264e-18 0.30
CTRO_HUMAN CIT Citron Rho-interacting kinase 9.444e-18 0.39
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 9.478e-18 0.39
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 3.725e-17 0.39
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 3.74e-17 0.39
RON_HUMAN MST1R Macrophage-stimulating protein receptor 5.539e-17 0.36
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.11e-16 0.39
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.11e-16 0.31
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 2.22e-16 0.36
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.22e-16 0.39
STK3_MOUSE Stk3 Serine/threonine-protein kinase 3 4.441e-16 0.35
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 6.661e-16 0.31
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.11e-15 0.39
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 1.332e-15 0.36
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.665e-15 0.40
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.22e-15 0.39
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 3.22e-15 0.30
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 5.107e-15 0.41
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 8.105e-15 0.28
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 8.438e-15 0.38
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.01e-14 0.30
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 1.288e-14 0.32
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.321e-14 0.39
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.343e-14 0.39
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.62e-14 0.41
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 3.908e-14 0.33
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 4.396e-14 0.53
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 6.661e-14 0.39
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 6.983e-14 0.43
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 8.737e-14 0.32
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.304e-14 0.53
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 9.359e-14 0.33
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.471e-13 0.31
ENV_HV1Y2 env Envelope glycoprotein gp160 1.725e-13 0.30
RNT1_ASPOR rntA Guanyl-specific ribonuclease T1 2.074e-13 0.29
KC1D_RAT Csnk1d Casein kinase I isoform delta 2.496e-13 0.32
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.757e-13 0.39
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 6.085e-13 0.38
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 7.131e-13 0.32
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 8.152e-13 0.35
AURKA_HUMAN AURKA Aurora kinase A 8.259e-13 0.44
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 8.792e-13 0.36
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.602e-12 0.39
DMPK_HUMAN DMPK Myotonin-protein kinase 5.871e-12 0.39
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 7.126e-12 0.29
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 1.119e-11 0.28
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.504e-11 0.39
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.505e-11 0.39
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.508e-11 0.33
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 1.535e-11 0.39
PRIO_HUMAN PRNP Major prion protein 1.839e-11 0.33
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 2.129e-11 0.39
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 2.223e-11 0.35
SHH_MOUSE Shh Sonic hedgehog protein 3.261e-11 0.31
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 3.53e-11 0.33
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 4.401e-11 0.35
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 4.607e-11 0.41
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 7.573e-11 0.39
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 8.077e-11 0.32
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 8.834e-11 0.39
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.119e-10 0.39
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.507e-10 0.39
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.584e-10 0.39
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 1.689e-10 0.35
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 1.689e-10 0.35
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.236e-10 0.39
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 3.703e-10 0.35
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 4.493e-10 0.35
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 4.547e-10 0.32
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 4.608e-10 0.39
TIE2_HUMAN TEK Angiopoietin-1 receptor 7.959e-10 0.44
C3SLN3_ECOLX gyrB DNA gyrase subunit B 8.903e-10 0.32
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 2.099e-09 0.39
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 2.099e-09 0.39
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 2.418e-09 0.29
AURKB_HUMAN AURKB Aurora kinase B 2.551e-09 0.44
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 3.088e-09 0.35
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.333e-09 0.30
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 4.209e-09 0.35
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 4.449e-09 0.39
LDHA_HUMAN LDHA L-lactate dehydrogenase A chain 5.282e-09 0.31
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 6e-09 0.35
PTGES_HUMAN PTGES Prostaglandin E synthase 6.081e-09 0.37
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 6.195e-09 0.32
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 6.494e-09 0.32
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 8.082e-09 0.30
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 8.492e-09 0.35
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 8.534e-09 0.31
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 8.815e-09 0.29
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 8.876e-09 0.35
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.046e-08 0.31
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 1.256e-08 0.35
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.321e-08 0.39
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1.361e-08 0.39
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 1.482e-08 0.35
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 1.781e-08 0.39
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.857e-08 0.32
MYO3A_HUMAN MYO3A Myosin-IIIa 1.857e-08 0.32
R1A_SARS Replicase polyprotein 1a 2.618e-08 0.33
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 3.314e-08 0.35
ACOD_HUMAN SCD Acyl-CoA desaturase 3.5e-08 0.38
PA21B_HUMAN PLA2G1B Phospholipase A2 3.845e-08 0.34
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 4.368e-08 0.35
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 4.643e-08 0.32
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 4.643e-08 0.32
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 4.643e-08 0.32
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 4.643e-08 0.32
MYO3B_HUMAN MYO3B Myosin-IIIb 4.643e-08 0.32
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 5.473e-08 0.38
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 6.2e-08 0.34
Q76353_9HIV1 Integrase 9.294e-08 0.35
GAK_HUMAN GAK Cyclin-G-associated kinase 1.083e-07 0.39
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.307e-07 0.35
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.454e-07 0.31
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.488e-07 0.35
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 1.779e-07 0.28
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.906e-07 0.34
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 2.136e-07 0.32
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 2.382e-07 0.34
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.428e-07 0.43
TSHR_HUMAN TSHR Thyrotropin receptor 2.466e-07 0.31
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 2.864e-07 0.31
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 4.068e-07 0.32
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 4.068e-07 0.32
TERT_HUMAN TERT Telomerase reverse transcriptase 4.76e-07 0.30
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 4.898e-07 0.35
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 5.33e-07 0.43
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 5.75e-07 0.33
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 5.847e-07 0.36
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 5.952e-07 0.37
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 6.644e-07 0.35
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 6.644e-07 0.35
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 7.231e-07 0.32
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 7.276e-07 0.32
AOFB_RAT Maob Amine oxidase [flavin-containing] B 8.805e-07 0.39
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 9.037e-07 0.39
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 9.923e-07 0.32
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 9.967e-07 0.35
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 1.013e-06 0.35
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.04e-06 0.41
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.119e-06 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.234e-06 0.32
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 1.6e-06 0.35
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 1.613e-06 0.31
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 1.649e-06 0.35
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.676e-06 0.37
TNFA_HUMAN TNF Tumor necrosis factor 1.726e-06 0.36
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 1.835e-06 0.36
INSRR_HUMAN INSRR Insulin receptor-related protein 1.999e-06 0.32
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 1.999e-06 0.32
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 2.213e-06 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 2.334e-06 0.42
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 2.586e-06 0.39
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 2.629e-06 0.32
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 3.112e-06 0.32
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 3.112e-06 0.32
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 3.112e-06 0.32
DYR_HUMAN DHFR Dihydrofolate reductase 3.184e-06 0.36
AGP1_YEAST AGP1 General amino acid permease AGP1 4.4e-06 0.30
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 4.555e-06 0.31
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 4.679e-06 0.32
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 4.679e-06 0.32
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 5.93e-06 0.39
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 6.485e-06 0.39
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 6.825e-06 0.32
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 6.825e-06 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.162e-06 0.34
HDA11_HUMAN HDAC11 Histone deacetylase 11 7.958e-06 0.33
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 8.822e-06 0.30
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 9.691e-06 0.32
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 9.691e-06 0.32
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 9.691e-06 0.32