Results of Job: search_60c572a5-189e-4245-9f06-522184ed0139

Query Target Key Target Name Description P-Value MaxTC

Chlorpromazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.058e-182 1.00
PRIO_MOUSE Prnp Major prion protein 2.9e-124 1.00
TYTR_TRYCR TPR Trypanothione reductase 3.76e-72 1.00
CALM_BOVIN CALM Calmodulin 7.968e-51 1.00
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.834e-42 1.00
CALM1_HUMAN CALM1 Calmodulin-1 5.32e-38 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.574e-21 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 1.685e-19 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.992e-18 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.634e-18 1.00
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.377e-17 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.11e-16 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 5.784e-14 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.27e-12 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.062e-12 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.669e-12 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.363e-11 1.00
PRIO_HUMAN PRNP Major prion protein 2.888e-11 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 9.555e-11 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.975e-10 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 1.356e-09 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.255e-09 1.00
DRD1_RAT Drd1 D(1A) dopamine receptor 2.885e-09 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.121e-08 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.257e-08 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.096e-08 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.451e-07 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 4.205e-07 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.592e-06 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.356e-05 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.438e-05 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.593e-05 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.079e-05 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.129e-05 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.269e-05 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 3.068e-05 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.09e-05 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.167e-05 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.039e-05 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.11e-05 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 6.907e-05 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 0.0001074 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 0.0002135 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 0.0004316 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 0.002932 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.002992 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.0136 1.00
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 0.0216 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.02522 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.03056 1.00
MC5R_HUMAN MC5R Melanocortin receptor 5 0.03611 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.05833 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.3343 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.8985 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.9775 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 0.9811 1.00
LYSC1_RAT Lyz1 Lysozyme C-1 7.076e-36 0.45
BGLR_RAT Gusb Beta-glucuronidase 1.042e-27 0.45
EBPL_HUMAN EBPL Emopamil-binding protein-like 1.042e-27 0.45
TYTR_TRYBB TPR Trypanothione reductase 1.787e-19 0.63
NOX1_HUMAN NOX1 NADPH oxidase 1 4.42e-18 0.38
HRH1_RAT Hrh1 Histamine H1 receptor 2.424e-17 0.78
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 2.22e-16 0.63
CHLE_HUMAN BCHE Cholinesterase 7.772e-16 0.43
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.221e-15 0.35
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 5.972e-13 0.36
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 8.976e-13 0.63
CHLE_HORSE BCHE Cholinesterase 5.972e-12 0.70
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 8.923e-11 0.34
DEF_STAAM def Peptide deformylase 8.213e-08 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.511e-07 0.29
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 3.963e-07 0.33
PERM_HUMAN MPO Myeloperoxidase 7.759e-07 0.38
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.14e-06 0.29
DPOL_VACCW POL DNA polymerase 1.971e-06 0.32
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.04e-06 0.37
ERG2_YEAST ERG2 C-8 sterol isomerase 4.6e-06 0.45
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.628e-06 0.34

Oxycodone

OPRD_HUMAN OPRD1 Delta-type opioid receptor 4.539e-167 1.00
OPRM_MOUSE Oprm1 Mu-type opioid receptor 8.172e-161 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 8.379e-137 1.00
OPRD_RAT Oprd1 Delta-type opioid receptor 2.321e-116 1.00
OPRM_RAT Oprm1 Mu-type opioid receptor 8.386e-103 1.00
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.097e-77 1.00
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.489e-164 0.78
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.178e-144 0.78
OPRM_BOVIN OPRM1 Mu-type opioid receptor 1.152e-125 0.59
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.14e-119 0.78
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 3.685e-108 0.59
OPRD_MOUSE Oprd1 Delta-type opioid receptor 5.053e-108 0.78
OPRX_CAVPO OPRL1 Nociceptin receptor 5.887e-89 0.43
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.54e-61 0.76
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 2.046e-28 0.48
ACES_TETCF ache Acetylcholinesterase 5.937e-22 0.38
NK1R_MOUSE Tacr1 Substance-P receptor 6.661e-16 0.30
ACES_RAT Ache Acetylcholinesterase 1.11e-15 0.38
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.887e-15 0.38
OPRX_HUMAN OPRL1 Nociceptin receptor 6.994e-15 0.40
OX1R_HUMAN HCRTR1 Orexin receptor type 1 4.312e-11 0.42
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 5.888e-10 0.31
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 6.538e-10 0.29
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 2.301e-08 0.31
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 5.429e-06 0.31
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 9.866e-06 0.33

Raloxifene

ESR1_HUMAN ESR1 Estrogen receptor 2.164e-161 1.00
ESR2_HUMAN ESR2 Estrogen receptor beta 8.935e-134 1.00
ESR1_RAT Esr1 Estrogen receptor 6.387e-47 1.00
ESR2_RAT Esr2 Estrogen receptor beta 3.3e-37 1.00
HRH3_HUMAN HRH3 Histamine H3 receptor 1.297e-94 0.45
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.75e-75 0.52
HRH3_RAT Hrh3 Histamine H3 receptor 2.899e-65 0.43
NORA_STAAU norA Quinolone resistance protein NorA 1.594e-64 0.39
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 4.984e-56 0.58
CHLE_HORSE BCHE Cholinesterase 7.283e-43 0.46
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 2.544e-42 0.33
HRH1_HUMAN HRH1 Histamine H1 receptor 1.879e-41 0.36
ACES_ELEEL ache Acetylcholinesterase 2.722e-40 0.46
HNMT_RAT Hnmt Histamine N-methyltransferase 1.562e-39 0.35
HRH3_MOUSE Hrh3 Histamine H3 receptor 7.208e-38 0.35
GGYF2_HUMAN GIGYF2 GRB10-interacting GYF protein 2 3.56e-37 0.29
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 5.432e-36 0.58
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 1.234e-34 0.36
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 8.015e-32 0.31
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 1.251e-31 0.36
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 3.829e-28 0.35
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.544e-25 0.29
HRH2_HUMAN HRH2 Histamine H2 receptor 1.085e-24 0.34
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.689e-23 0.58
HRH3_CAVPO HRH3 Histamine H3 receptor 3.606e-18 0.35
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 7.773e-18 0.28
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 1.11e-16 0.32
ACES_MOUSE Ache Acetylcholinesterase 2.22e-16 0.31
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 4.441e-16 0.30
ROCK2_RAT Rock2 Rho-associated protein kinase 2 1.876e-14 0.30
HRH1_CAVPO HRH1 Histamine H1 receptor 2.575e-13 0.35
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 8.622e-13 0.40
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 9.442e-13 0.33
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.116e-12 0.38
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 3.776e-12 0.37
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 4.978e-12 0.34
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 6.249e-12 0.36
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 9.994e-12 0.34
IKKB_MOUSE Ikbkb Inhibitor of nuclear factor kappa-B kinase subunit beta 1.133e-11 0.33
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.243e-11 0.37
NR1H4_MOUSE Nr1h4 Bile acid receptor 1.668e-11 0.29
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.774e-11 0.36
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.072e-11 0.39
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.374e-11 0.44
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.217e-10 0.36
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.545e-10 0.37
GYRB_MYCSM gyrB DNA gyrase subunit B 3.847e-10 0.33
TERT_HUMAN TERT Telomerase reverse transcriptase 6.796e-10 0.30
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.479e-09 0.47
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 3.716e-09 0.43
TLR9_HUMAN TLR9 Toll-like receptor 9 7.287e-09 0.34
V1BR_RAT Avpr1b Vasopressin V1b receptor 9.071e-09 0.29
ACES_HUMAN ACHE Acetylcholinesterase 9.942e-09 0.44
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.103e-08 0.42
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.728e-08 0.34
HRH2_CAVPO HRH2 Histamine H2 receptor 2.006e-08 0.34
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.201e-08 0.38
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 2.985e-08 0.39
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 3.564e-08 0.36
Q63380_RAT NET Transporter 8.261e-08 0.36
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.426e-07 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 1.463e-07 0.34
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 2.237e-07 0.36
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 2.423e-07 0.37
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.507e-07 0.30
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 5.526e-07 0.29
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 6.513e-07 0.42
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 9.96e-07 0.36
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.044e-06 0.38
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 2.446e-06 0.35
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.044e-06 0.32
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 4.584e-06 0.36
AURKB_HUMAN AURKB Aurora kinase B 4.907e-06 0.33
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 5.557e-06 0.29
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 6.149e-06 0.34
Q865E1_MACMU HRH3 Histamine receptor H3 6.728e-06 0.36
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 7.112e-06 0.29
ACVR1_HUMAN ACVR1 Activin receptor type-1 8.442e-06 0.36
LCK_HUMAN LCK Tyrosine-protein kinase Lck 8.766e-06 0.36
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 9.208e-06 0.28
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 9.672e-06 0.34

Nabilone

CNR2_MOUSE Cnr2 Cannabinoid receptor 2 7.21e-155 1.00
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.33e-82 1.00
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.205e-51 1.00
CNR1_HUMAN CNR1 Cannabinoid receptor 1 6.759e-49 1.00
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 3.721e-24 0.46
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 4.397e-06 0.46

Lenalidomide

IKZF1_HUMAN IKZF1 DNA-binding protein Ikaros 1.288e-130 1.00
CRBN_HUMAN CRBN Protein cereblon 2.331e-108 1.00
AMPN_MOUSE Anpep Aminopeptidase N 1.647e-10 0.28
VACHT_TETCF Vesicular acetylcholine transporter 2.651e-10 0.31
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 5.272e-07 0.29

Zidovudine

KTHY_MYCTU tmk Thymidylate kinase 6.822e-121 1.00
KITH_HUMAN TK1 Thymidine kinase, cytosolic 5.061e-101 1.00
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 7.558e-26 1.00
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 8.341e-12 1.00
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 1.114e-11 1.00
Q72874_9HIV1 pol Pol polyprotein 0.9928 1.00
TYPH_RAT Tymp Thymidine phosphorylase 1.329e-104 0.47
TYSY_LACCA thyA Thymidylate synthase 8.019e-103 0.57
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 1.477e-101 0.44
A3RLP8_CHV1 UL23 Thymidine kinase 8.174e-100 0.71
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 1.695e-99 0.57
DNK_DROME dnk Deoxynucleoside kinase 2.871e-92 0.54
DPOD1_HUMAN POLD1 DNA polymerase delta catalytic subunit 2.987e-87 0.70
KITH_RAT Tk1 Thymidine kinase, cytosolic 8.409e-81 0.60
KITH_VZVD TK Thymidine kinase 3.396e-78 0.34
D3ZGQ2_RAT Tk2 Thymidine kinase 2 5.501e-72 0.58
KITH_HHV1S TK Thymidine kinase 6.663e-72 0.71
KTHY_HUMAN DTYMK Thymidylate kinase 4.922e-65 0.39
TYSY_BOVIN TYMS Thymidylate synthase 1.503e-59 0.39
TYSY_MYCTU thyA Thymidylate synthase ThyA 1.289e-54 0.44
DPOL_HHV1K DNA polymerase catalytic subunit 5.761e-43 0.70
Q6L709_HHV2 TK Thymidine kinase 1.049e-42 0.42
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 7.174e-42 0.41
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 7.418e-39 0.49
NT5M_HUMAN NT5M 5'(3')-deoxyribonucleotidase, mitochondrial 2.333e-36 0.29
DPOL_HHV11 DNA polymerase catalytic subunit 5.517e-31 0.70
DPOL_VZVD DNA polymerase catalytic subunit 5.517e-31 0.70
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 2.797e-27 0.39
KITH_VZVO TK Thymidine kinase 1.246e-25 0.32
DPOLB_HUMAN POLB DNA polymerase beta 6.561e-25 0.51
KITH_HHV1 TK Thymidine kinase 2.921e-23 0.49
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 7.4e-22 0.40
TYPH_HUMAN TYMP Thymidine phosphorylase 9.133e-22 0.52
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.369e-18 0.49
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 3.808e-18 0.40
TYSY_MOUSE Tyms Thymidylate synthase 2.543e-17 0.54
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 3.331e-16 0.31
P2RY6_RAT P2ry6 P2Y purinoceptor 6 1.446e-13 0.30
Q03732_HBV HBcAg Capsid protein 1.144e-12 0.71
ADA_BOVIN ADA Adenosine deaminase 3.352e-12 0.36
CHLE_HUMAN BCHE Cholinesterase 2.545e-11 0.43
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.425e-10 0.52
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 1.88e-10 0.40
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 4.897e-10 0.29
TYSY_HUMAN TYMS Thymidylate synthase 3.67e-09 0.47
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.052e-07 0.37

Cefotaxime

S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 3.198e-112 1.00
B2ZTR6_ACIBA Beta-lactamase 2.17e-107 1.00
D6NSM8_ACIBA ampC Beta-lactamase 2.17e-107 1.00
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.148e-69 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.601e-60 1.00
PBPA_PSEAE mrcA Penicillin-binding protein 1A 2.173e-93 0.43
Q83TT7_ECOLX ampC AmpC 2.719e-64 0.43
Q7DHH4_STAAU mecA MecA 1.968e-44 0.35
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 7.004e-35 0.43
A2RP81_CITFR blaPER-2 Beta-lactamase 4.961e-34 0.43
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 7.026e-31 0.38
Q3S5C3_SALNE sugE Efflux transporter 6.051e-27 0.43
Q48435_KLEPN bla LAT-2 Beta-lactamase 6.051e-27 0.43
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.418e-21 0.38
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.982e-18 0.35
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.331e-15 0.72
AMPC_CITFR ampC Beta-lactamase 3.775e-15 0.38
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.552e-15 0.62
AMPC_ENTCL ampC Beta-lactamase 3.125e-12 0.39
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 5.255e-10 0.34
Q59401_ENTCL Beta-lactamase 5.852e-08 0.31
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 7.656e-08 0.71
STRP_STRP1 ska Streptokinase A 8.247e-08 0.67
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 1.107e-07 0.33
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.313e-06 0.62

Sotalol

ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.646e-105 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.594e-54 1.00
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 5.75e-53 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 8.489e-47 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.802e-102 0.64
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.946e-49 0.58
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 5.806e-49 0.58
ADRB3_MOUSE Adrb3 Beta-3 adrenergic receptor 3.164e-45 0.36
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 8.42e-41 0.43
NMDZ1_MOUSE Grin1 Glutamate receptor ionotropic, NMDA 1 1.579e-38 0.31
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 3.868e-35 0.50
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 3.071e-28 0.40
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 5.701e-26 0.50
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.29e-22 0.50
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 3.603e-22 0.32
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 6.753e-22 0.40
GRIA4_HUMAN GRIA4 Glutamate receptor 4 3.818e-20 0.36
UT2_RAT Slc14a2 Urea transporter 2 4.501e-19 0.37
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.247e-18 0.31
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 2.486e-18 0.31
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 1.11e-15 0.30
G3HDX1_CRIGR Alpha-1B adrenergic receptor 6.328e-15 0.28
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.096e-13 0.29
UT1_RAT Slc14a1 Urea transporter 1 1.87e-13 0.37
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 2.682e-12 0.50
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 8.628e-12 0.38
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 5.414e-11 0.50
TA2R_RAT Tbxa2r Thromboxane A2 receptor 1.04e-09 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.404e-09 0.44
PSBA_MARPO psbA Photosystem II protein D1 2.903e-09 0.29
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 5.367e-09 0.30
GRIA4_RAT Gria4 Glutamate receptor 4 5.981e-07 0.38
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 5.398e-06 0.32

Buspirone

5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.699e-99 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.612e-61 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 1.103e-56 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.653e-47 1.00
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.376e-47 1.00
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 8.904e-29 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.369e-22 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.035e-20 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.917e-20 1.00
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 5.133e-19 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 5.888e-19 1.00
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.311e-18 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.331e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.842e-14 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.882e-11 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.003448 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.007266 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.02292 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.644e-77 0.57
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.967e-75 0.35
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.206e-43 0.49
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 7.314e-42 0.57
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 5.895e-32 0.39
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.227e-28 0.57
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 6.772e-27 0.50
DRD4_RAT Drd4 D(4) dopamine receptor 1.396e-26 0.46
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.043e-22 0.50
P2RX3_RAT P2rx3 P2X purinoceptor 3 1.152e-22 0.34
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 5.372e-21 0.46
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.901e-21 0.46
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 1.221e-15 0.30
VATB1_HUMAN ATP6V1B1 V-type proton ATPase subunit B, kidney isoform 2.22e-15 0.34
VPP1_CHICK ATP6V0A1 V-type proton ATPase 116 kDa subunit a isoform 1 2.22e-15 0.34
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.553e-15 0.33
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.276e-14 0.54
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 3.181e-13 0.30
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.125e-11 0.45
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 7.879e-11 0.32
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 9.675e-11 0.33
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.46e-10 0.32
DRD1_HUMAN DRD1 D(1A) dopamine receptor 5.583e-10 0.47
HRH1_HUMAN HRH1 Histamine H1 receptor 1.063e-09 0.45
DRD3_RAT Drd3 D(3) dopamine receptor 1.402e-09 0.53
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 3.988e-07 0.33
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 1.395e-06 0.41
ACES_ELEEL ache Acetylcholinesterase 2.726e-06 0.35
CASP5_HUMAN CASP5 Caspase-5 6.433e-06 0.29

Entacapone

COMT_RAT Comt Catechol O-methyltransferase 3.033e-97 1.00
COMT_HUMAN COMT Catechol O-methyltransferase 1.603e-20 1.00
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.908e-17 1.00
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 4.222e-75 0.39
DYN1_HUMAN DNM1 Dynamin-1 3.372e-73 0.44
MOT1_RAT Slc16a1 Monocarboxylate transporter 1 1.162e-52 0.38
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.901e-39 0.39
COMT_PIG COMT Catechol O-methyltransferase 7.594e-32 0.47
Q9XQA6_POAAN psbA Photosystem II protein D1 1.11e-16 0.32
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 4.774e-15 0.35
EPHA3_MOUSE Epha3 Ephrin type-A receptor 3 6.861e-13 0.32
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.061e-08 0.43
TTHY_HUMAN TTR Transthyretin 8.678e-08 0.38
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.668e-06 0.31

Flutamide

ANDR_RAT Ar Androgen receptor 1.145e-82 1.00
ANDR_HUMAN AR Androgen receptor 4.508e-14 1.00
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 0.002098 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.004281 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.8175 1.00
COLA_CLOPE colA Collagenase ColA 3.367e-116 0.38
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 1.909e-53 0.41
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 3.061e-52 0.34
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 9.433e-49 0.41
KCNB2_HUMAN KCNB2 Potassium voltage-gated channel subfamily B member 2 1.973e-43 0.34
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 6.559e-40 0.37
KLF10_HUMAN KLF10 Krueppel-like factor 10 2.57e-39 0.31
PPOM_TOBAC PPXII Protoporphyrinogen oxidase, mitochondrial 1.071e-38 0.31
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.44e-34 0.44
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.328e-29 0.35
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 2.378e-29 0.30
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 2.092e-28 0.35
MYOC_HUMAN MYOC Myocilin 6.243e-24 0.29
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.45e-23 0.34
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 8.195e-23 0.35
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.73e-20 0.31
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 4.621e-20 0.35
BLM_HUMAN BLM Bloom syndrome protein 5.52e-20 0.31
PSBA_MARPO psbA Photosystem II protein D1 8.47e-19 0.31
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.07e-18 0.34
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 5.282e-18 0.35
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 1.11e-16 0.32
UT2_RAT Slc14a2 Urea transporter 2 8.882e-16 0.30
HPPD_RAT Hpd 4-hydroxyphenylpyruvate dioxygenase 3.442e-15 0.33
KTHY_HUMAN DTYMK Thymidylate kinase 9.504e-14 0.30
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 1.14e-13 0.30
PSBA_SPIOL psbA Photosystem II protein D1 1.915e-13 0.33
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 2.663e-13 0.33
PRGR_RAT Pgr Progesterone receptor 4.751e-13 0.28
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 1.279e-12 0.37
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.314e-12 0.33
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 2.957e-12 0.33
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 4.437e-12 0.33
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 4.989e-12 0.37
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 5.391e-12 0.35
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 1.23e-11 0.28
UT1_RAT Slc14a1 Urea transporter 1 3.542e-11 0.30
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 5.659e-11 0.29
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 1.66e-10 0.31
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 3.796e-10 0.38
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 4.084e-10 0.29
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.243e-09 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.342e-09 0.38
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 2.942e-09 0.32
MCR_RAT Nr3c2 Mineralocorticoid receptor 2.992e-09 0.29
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 4.099e-09 0.28
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 4.794e-09 0.33
FA11_HUMAN F11 Coagulation factor XI 2.629e-08 0.38
VCAM1_HUMAN VCAM1 Vascular cell adhesion protein 1 3.457e-08 0.31
CML1_HUMAN CMKLR1 Chemokine-like receptor 1 3.605e-08 0.33
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 6.101e-08 0.30
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 8.744e-08 0.35
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 1.119e-07 0.42
MYO3B_HUMAN MYO3B Myosin-IIIb 1.511e-07 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.668e-07 0.42
EXSA_PSEAE exsA Exoenzyme S synthesis regulatory protein ExsA 2.129e-07 0.29
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.509e-07 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.557e-07 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 3.814e-07 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 4.528e-07 0.32
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 6.257e-07 0.29
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 7.763e-07 0.32
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.094e-06 0.30
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.14e-06 0.29
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.177e-06 0.30
EST1_RABIT Liver carboxylesterase 1 1.371e-06 0.29
Q9FYV8_MAIZE Protoporphyrinogen oxidase 1.488e-06 0.33
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.663e-06 0.32
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 2.72e-06 0.29
C3SLB7_ECOLX glmU Bifunctional protein GlmU 3.073e-06 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 3.799e-06 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 4.484e-06 0.30
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 4.933e-06 0.29
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 5.02e-06 0.29
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.938e-06 0.30
ANDR_MOUSE Ar Androgen receptor 6.292e-06 0.68
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 6.957e-06 0.31
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 7.581e-06 0.29

Miglitol

SUIS_HUMAN SI Sucrase-isomaltase, intestinal 2.742e-78 1.00
LYAG_HUMAN GAA Lysosomal alpha-glucosidase 3.469e-68 1.00
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 7.967e-68 1.00
GDE_RABIT AGL Glycogen debranching enzyme 1.383e-56 1.00
SUIS_RAT Si Sucrase-isomaltase, intestinal 1.577e-40 1.00
LYAG_RAT Gaa Lysosomal alpha-glucosidase 1.422e-24 1.00
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 2.92e-282 0.68
CEGT_MOUSE Ugcg Ceramide glucosyltransferase 1.004e-192 0.64
B5THE3_MOUSE Sis Sucrase-isomaltase 8.416e-178 0.68
LYAG_MOUSE Gaa Lysosomal alpha-glucosidase 3.684e-159 0.66
CEGT_HUMAN UGCG Ceramide glucosyltransferase 8.988e-157 0.68
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 2.61e-121 0.64
Q9LGC6_ORYSJ P0504H10.9 Putative alpha-glucosidase 1.406e-107 0.72
GDE_HUMAN AGL Glycogen debranching enzyme 1.251e-92 0.68
GBA2_MOUSE Gba2 Non-lysosomal glucosylceramidase 1.825e-84 0.68
P94451_GEOSE Alpha-amylase 4.394e-64 0.40
BGLS_RHIRD cbg-1 Beta-glucosidase 3.253e-58 0.36
LPH_HUMAN LCT Lactase-phlorizin hydrolase 1.049e-52 0.42
BGAL_RHIML lacZ Beta-galactosidase 1.472e-45 0.36
LPH_RAT Lct Lactase-phlorizin hydrolase 3.938e-44 0.59
BGAL_ECOLI lacZ Beta-galactosidase 8.889e-42 0.36
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 3.24e-41 0.41
AGALC_ASPNG aglC Alpha-galactosidase C 3.56e-37 0.29
AGAL_COFAR Alpha-galactosidase 3.605e-35 0.36
BGAL_HUMAN GLB1 Beta-galactosidase 4.227e-35 0.36
GANAB_HUMAN GANAB Neutral alpha-glucosidase AB 3.682e-30 0.29
Q43014_PRUAV Beta-glucosidase 6.243e-24 0.29
BGLS_AGRSA abg Beta-glucosidase 2e-23 0.29
PYGL_RAT Pygl Glycogen phosphorylase, liver form 1.923e-21 0.33
GANC_MOUSE Ganc Neutral alpha-glucosidase C 1.523e-18 0.29
BGAL_BOVIN GLB1 Beta-galactosidase 1.183e-17 0.36
B4EH87_BURCJ Lectin 5.551e-16 0.30
LYAG_BOVIN GAA Lysosomal alpha-glucosidase 1.665e-15 0.29
Q8AAK6_BACTN Beta-mannosidase 2.757e-12 0.30
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 4.628e-12 0.29
BGAL_ECOLX lacZ Beta-galactosidase 1.857e-11 0.36
AGAL_HUMAN GLA Alpha-galactosidase A 2.039e-09 0.29
FUCO_BOVIN FUCA1 Tissue alpha-L-fucosidase 2.243e-08 0.29

Fosinopril

ACE_HUMAN ACE Angiotensin-converting enzyme 5.674e-73 1.00
ACE_RABIT ACE Angiotensin-converting enzyme 6.228e-64 0.65
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.914e-62 0.36
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 1.274e-55 0.33
PPCE_PIG PREP Prolyl endopeptidase 9.536e-51 0.33
ACE_RAT Ace Angiotensin-converting enzyme 1.017e-38 0.47
PPCE_BOVIN PREP Prolyl endopeptidase 6.486e-29 0.35
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.868e-27 0.36
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 5.079e-18 0.31
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 7.772e-15 0.33
NEP_RABIT MME Neprilysin 3.99e-12 0.34
PPCE_MOUSE Prep Prolyl endopeptidase 9.554e-12 0.32
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.675e-10 0.28
CLTR2_HUMAN CYSLTR2 Cysteinyl leukotriene receptor 2 9.01e-10 0.31
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 4.251e-09 0.30
ACE_MOUSE Ace Angiotensin-converting enzyme 6.612e-08 0.33
PPCE_HUMAN PREP Prolyl endopeptidase 1.326e-07 0.35
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.755e-07 0.35
CATD_BOVIN CTSD Cathepsin D 1.807e-07 0.35
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 2.041e-07 0.29
NEP_RAT Mme Neprilysin 3.68e-07 0.42
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 1.565e-06 0.31
MMP3_HUMAN MMP3 Stromelysin-1 2.382e-06 0.32
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 6.257e-06 0.31

Rimantadine

M2_I72A8 M Matrix protein 2 8.798e-51 1.00
M2_I000F M Matrix protein 2 2.478e-35 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 3.331e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
Q20MD5_I72A8 M2 Matrix protein 2 1.396e-08 0.32

Duloxetine

Q63380_RAT NET Transporter 1.803e-33 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.098e-13 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.289e-13 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 8.753e-06 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.171e-05 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.178e-05 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.004713 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.8217 1.00
INAR1_HUMAN IFNAR1 Interferon alpha/beta receptor 1 1.356e-39 0.31
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 1.575e-19 0.38
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.11e-16 0.36
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 9.026e-14 0.38
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 9.026e-14 0.38
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.143e-12 0.36
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.826e-10 0.35
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 4.154e-08 0.48
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.271e-07 0.36
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 3.307e-07 0.39
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.775e-06 0.39

Darifenacin

Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.756e-26 1.00
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 5.906e-23 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.936e-18 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.566e-17 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 8.882e-16 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.665e-15 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.665e-15 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.379e-11 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.523e-07 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.198e-06 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.001297 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 0.002212 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 0.2312 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 0.2982 1.00
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 6.861e-90 0.38
CRTN_STAAE crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 2.302e-32 0.34
G3H407_CRIGR PROKR2 1.652e-29 0.36
KCNJ1_HUMAN KCNJ1 ATP-sensitive inward rectifier potassium channel 1 2.277e-25 0.37
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 4.577e-23 0.31
EHMT2_MOUSE Ehmt2 Histone-lysine N-methyltransferase EHMT2 5.518e-23 0.28
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 7.035e-22 0.36
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 3.293e-21 0.33
ACES_MOUSE Ache Acetylcholinesterase 9.159e-21 0.32
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.321e-19 0.35
EBPL_HUMAN EBPL Emopamil-binding protein-like 2.139e-18 0.29
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.266e-17 0.35
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 3.638e-17 0.30
MEN1_HUMAN MEN1 Menin 1.11e-16 0.29
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.11e-16 0.35
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.331e-16 0.34
HRH1_CAVPO HRH1 Histamine H1 receptor 4.441e-16 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 8.882e-16 0.36
G3HIE5_CRIGR Prokineticin receptor 1 9.992e-16 0.33
KCNJ1_RAT Kcnj1 ATP-sensitive inward rectifier potassium channel 1 1.11e-15 0.36
OPRM_RAT Oprm1 Mu-type opioid receptor 2.22e-15 0.41
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 5.218e-15 0.33
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 7.327e-15 0.30
GP183_MOUSE Gpr183 G-protein coupled receptor 183 7.883e-15 0.29
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 1.166e-14 0.35
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.62e-14 0.30
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.709e-14 0.38
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.209e-13 0.38
Q9QXI6_MOUSE Slc5a1 SGLT1 protein 1.372e-13 0.30
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.217e-13 0.31
CXL10_HUMAN CXCL10 C-X-C motif chemokine 10 7.603e-13 0.32
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.333e-12 0.36
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 8.352e-12 0.32
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 9.49e-12 0.36
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.053e-11 0.32
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.123e-11 0.32
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.174e-11 0.37
DRD3_HUMAN DRD3 D(3) dopamine receptor 8.39e-11 0.38
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 2.047e-10 0.32
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.314e-10 0.40
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 5.699e-10 0.36
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 6.538e-10 0.29
ACES_HUMAN ACHE Acetylcholinesterase 1.166e-09 0.37
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 2.316e-09 0.32
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.123e-09 0.38
DRD2_MOUSE Drd2 D(2) dopamine receptor 7.729e-09 0.31
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.778e-09 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 1.702e-08 0.29
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 6.661e-08 0.32
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.008e-07 0.39
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 2.014e-07 0.35
ACES_RAT Ache Acetylcholinesterase 9.982e-07 0.32
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.435e-06 0.29
RYR2_HUMAN RYR2 Ryanodine receptor 2 1.467e-06 0.35
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.01e-06 0.35
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.346e-06 0.30
GP183_HUMAN GPR183 G-protein coupled receptor 183 3.242e-06 0.29
HRH1_RAT Hrh1 Histamine H1 receptor 4.157e-06 0.32
G3I1B6_CRIGR 5-hydroxytryptamine receptor 5.769e-06 0.30
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 6.733e-06 0.30
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.417e-06 0.35

Tolmetin

IL8_HUMAN CXCL8 Interleukin-8 1.251e-18 1.00
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.68e-13 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 2.514e-05 1.00
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 0.001258 1.00
DHRS9_RAT Dhrs9 Dehydrogenase/reductase SDR family member 9 1.535e-24 0.30
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.331e-16 0.31
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.443e-15 0.34
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 5.884e-15 0.28
HELD_ECOLI helD DNA helicase IV 7.883e-15 0.28
Q9I056_PSEAE cpg2 Carboxypeptidase G2 2.986e-13 0.29
EST1_RABIT Liver carboxylesterase 1 7.408e-12 0.38
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.62e-10 0.44
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 1.582e-09 0.30
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 1.385e-08 0.32
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 4.208e-08 0.32
S1PR1_RAT S1pr1 Sphingosine 1-phosphate receptor 1 4.372e-08 0.32
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 9.266e-08 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.178e-07 0.28
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.378e-07 0.36
UCHL1_HUMAN UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 2.601e-07 0.30
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.905e-07 0.29
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 5.533e-07 0.28
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 1.336e-06 0.29
EIS_MYCTU eis N-acetyltransferase Eis 2.124e-06 0.28
BLA2_BACCE blm Metallo-beta-lactamase type 2 3.572e-06 0.30
EST2_HUMAN CES2 Cocaine esterase 4.831e-06 0.38
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 4.887e-06 0.36
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 5.814e-06 0.32
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 6.384e-06 0.29
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 6.433e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.85e-06 0.28
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 8.241e-06 0.32
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.499e-06 0.35

Dicloxacillin

STRP_STRP1 ska Streptokinase A 8.436e-06 1.00
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.212e-66 0.84
Q3S5C3_SALNE sugE Efflux transporter 2.596e-51 0.84
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.596e-51 0.84
GPBAR_RAT Gpbar1 G-protein coupled bile acid receptor 1 4.842e-37 0.31
BLAB_BACCE Metallo-beta-lactamase type 2 1.214e-32 0.37
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 2.165e-29 0.39
NCAP_I33A0 NP Nucleoprotein 5.643e-28 0.35
GHSR_MOUSE Ghsr Growth hormone secretagogue receptor type 1 2.667e-27 0.34
NR1H4_HUMAN NR1H4 Bile acid receptor 6.595e-24 0.31
A2RP81_CITFR blaPER-2 Beta-lactamase 3.663e-18 0.40
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 1.155e-17 0.35
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 8.882e-16 0.48
Q7T1G6_DANRE trpn1 Ion channel NompC 1.443e-10 0.35
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 1.124e-08 0.33
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.083e-07 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.083e-07 0.30
AMPC_ECOLI ampC Beta-lactamase 4.107e-07 0.39
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 2.084e-06 0.37
NR1H4_MOUSE Nr1h4 Bile acid receptor 5.652e-06 0.28

Amikacin

RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 0.005635 1.00
CXB2_HUMAN GJB2 Gap junction beta-2 protein 5.653e-81 0.65
Q77YF8_HV1H2 rev Protein Rev 9.311e-70 0.52
LEG4_HUMAN LGALS4 Galectin-4 2.038e-60 0.35
LEG8_HUMAN LGALS8 Galectin-8 2.038e-60 0.35
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 1.52e-40 0.32
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.428e-34 0.33
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 3.807e-32 0.31
LEG3_HUMAN LGALS3 Galectin-3 3.146e-27 0.35
CHIT_YEAST CTS1 Endochitinase 7.459e-25 0.31
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 1.161e-23 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.657e-21 0.33
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 3.429e-19 0.30
TYRO_HUMAN TYR Tyrosinase 4.971e-18 0.30
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.754e-17 0.65
B4EH87_BURCJ Lectin 1.554e-15 0.30
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 2.442e-15 0.33
MAG_HUMAN MAG Myelin-associated glycoprotein 6.772e-15 0.30
TAT_HV112 tat Protein Tat 2.899e-13 0.34
CD69_HUMAN CD69 Early activation antigen CD69 3.091e-12 0.30
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.468e-10 0.58
LEF_BACAN lef Lethal factor 1.709e-10 0.45
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 9.403e-08 0.29
LEG9_HUMAN LGALS9 Galectin-9 3.277e-07 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 7.497e-07 0.33
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.678e-06 0.30
CHIA_HUMAN CHIA Acidic mammalian chitinase 7.02e-06 0.31

Altretamine

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.9778 1.00
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 4.348e-28 0.41
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.401e-06 0.31

Celecoxib

PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 9.182e-192 0.81
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 9.6e-112 0.81
Q8SPQ9_CANLF PTGS2 Cyclooxygenase 2 2.627e-105 0.49
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 1.662e-96 0.81
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.239e-80 0.65
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.92e-71 0.65
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.016e-70 0.65
CAH12_HUMAN CA12 Carbonic anhydrase 12 7.177e-66 0.46
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 2.545e-57 0.37
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.355e-55 0.78
PGH1_CANLF PTGS1 Prostaglandin G/H synthase 1 1.375e-52 0.47
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 3.375e-47 0.38
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.419e-45 0.46
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 2.489e-42 0.77
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 3.347e-39 0.33
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 9.903e-36 0.40
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.002e-33 0.46
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 3.632e-33 0.30
B2V8E3_SULSY Carbonate dehydratase 2.813e-32 0.46
Q31FD6_HYDCU Carbonic anhydrase, alpha family 2.813e-32 0.46
CAH4_HUMAN CA4 Carbonic anhydrase 4 7.139e-32 0.40
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 9.759e-32 0.46
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 2.109e-31 0.46
A6YCJ1_9METZ Astrosclerin-3 1.437e-30 0.46
C0IX24_STYPI CA2 Carbonic anhydrase 6.096e-30 0.46
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.466e-29 0.46
B5SU02_STYPI CA Alpha carbonic anhydrase 8.474e-29 0.46
CAH_METTE Carbonic anhydrase 2.164e-27 0.32
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.419e-27 0.46
CYNT_HELPY cynT Carbonic anhydrase 5.587e-27 0.46
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 4.483e-26 0.34
CAH14_HUMAN CA14 Carbonic anhydrase 14 8.773e-26 0.40
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.034e-25 0.40
A0A060INS8_CAPHI CTSH Cathepsin H 2.667e-24 0.41
CAH7_HUMAN CA7 Carbonic anhydrase 7 6.993e-24 0.46
STIM1_HUMAN STIM1 Stromal interaction molecule 1 7.717e-23 0.31
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 1.457e-22 0.31
Q5TU56_ANOGA 1272966 Carbonic anhydrase 3.183e-22 0.32
CAH15_MOUSE Ca15 Carbonic anhydrase 15 9.849e-22 0.46
H9B8T9_CAPHI CTSB Cathepsin B 7.177e-21 0.41
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.133e-20 0.45
CAH13_HUMAN CA13 Carbonic anhydrase 13 3.688e-20 0.40
CAN_CANAL NCE103 Carbonic anhydrase 2.082e-19 0.46
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 4.43e-19 0.30
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.401e-18 0.46
CAH4_BOVIN CA4 Carbonic anhydrase 4 1.11e-16 0.35
CAN_YEAST NCE103 Carbonic anhydrase 1.11e-16 0.32
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 1.11e-16 0.32
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 1.11e-16 0.66
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.11e-16 0.46
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.22e-16 0.32
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.353e-14 0.46
FA10_RABIT F10 Coagulation factor X 1.437e-12 0.34
SDHB_HUMAN SDHB Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial 1.621e-12 0.38
AGP1_YEAST AGP1 General amino acid permease AGP1 3.208e-11 0.30
PGH1_MOUSE Ptgs1 Prostaglandin G/H synthase 1 3.856e-11 0.30
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 1.317e-10 0.43
MCR_HUMAN NR3C2 Mineralocorticoid receptor 5.558e-10 0.52
RARG_HUMAN RARG Retinoic acid receptor gamma 1.198e-09 0.39
V9HWB9_HUMAN HEL-S-133P L-lactate dehydrogenase 1.496e-09 0.30
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.562e-09 0.32
FA10_HUMAN F10 Coagulation factor X 5.281e-09 0.40
CAH1_HORSE CA1 Carbonic anhydrase 1 8.719e-09 0.29
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 9.865e-09 0.35
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.744e-08 0.44
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 2.114e-08 0.34
METC_ECOLI metC Cystathionine beta-lyase MetC 8.775e-08 0.30
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 8.894e-08 0.51
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 1.031e-07 0.35
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.187e-07 0.33
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 1.236e-06 0.34
PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 1.367e-06 0.42
RPGF4_HUMAN RAPGEF4 Rap guanine nucleotide exchange factor 4 1.921e-06 0.35
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.521e-06 0.29
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.849e-06 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 2.901e-06 0.39
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 4.401e-06 0.37
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 5.196e-06 0.40
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 6.152e-06 0.30

Pefloxacin

ACEA_MYCTU icl Isocitrate lyase 8.633e-92 0.68
GLYCP_NIPAV G Glycoprotein G 1.096e-87 0.51
Q47245_ECOLX gyrA DNA gyrase subunit A 2.086e-64 0.51
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.451e-61 0.49
C3SLN2_ECOLX gyrB DNA gyrase subunit B 9.089e-56 0.51
WDR5_HUMAN WDR5 WD repeat-containing protein 5 1.99e-42 0.32
DPO3_BACSU polC DNA polymerase III PolC-type 4.301e-38 0.53
Q76353_9HIV1 Integrase 4.645e-30 0.44
5HT6R_MOUSE Htr6 5-hydroxytryptamine receptor 6 2.847e-23 0.29
PARC_STAAU parC DNA topoisomerase 4 subunit A 1.248e-22 0.78
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 2.49e-19 0.43
DPO1_THEAQ polA DNA polymerase I, thermostable 3.886e-15 0.30
Q7ZJM1_9HIV1 pol Integrase 1.055e-14 0.43
P2Y12_RAT P2ry12 P2Y purinoceptor 12 5.1e-13 0.31
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5.05e-12 0.38
ASH2L_HUMAN ASH2L Set1/Ash2 histone methyltransferase complex subunit ASH2 1.272e-10 0.28
RBBP5_HUMAN RBBP5 Retinoblastoma-binding protein 5 1.272e-10 0.28
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 5.781e-10 0.36
1433G_HUMAN YWHAG 14-3-3 protein gamma 2.37e-09 0.33
NDKB_HUMAN NME2 Nucleoside diphosphate kinase B 2.795e-09 0.31
CNR2_HUMAN CNR2 Cannabinoid receptor 2 5.21e-09 0.41
BRPF1_HUMAN BRPF1 Peregrin 2.319e-08 0.32
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.601e-08 0.41
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 4.424e-08 0.28
PARE_STAAU parE DNA topoisomerase 4 subunit B 1.764e-07 0.51
STRP_STRP1 ska Streptokinase A 1.941e-07 0.63
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.421e-07 0.32
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.205e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.205e-07 0.29
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 6.896e-07 0.36
GYRA_ECOLI gyrA DNA gyrase subunit A 8.548e-07 0.51
GYRA_MYCTU gyrA DNA gyrase subunit A 1.89e-06 0.33
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 1.964e-06 0.67
TAF1_HUMAN TAF1 Transcription initiation factor TFIID subunit 1 2.144e-06 0.29
GYRA_STAAU gyrA DNA gyrase subunit A 3.459e-06 0.51
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 3.495e-06 0.31
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 4.957e-06 0.28

Gallamine_triethiodide

ACH10_HUMAN CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 2.086e-56 0.45
ACHA9_HUMAN CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 2.086e-56 0.45
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 6.029e-14 0.38
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 7.494e-14 0.30
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.922e-13 0.29
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.628e-09 0.40
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.674e-08 0.32
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.092e-08 0.40
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 7.713e-08 0.40
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.696e-07 0.40
SC5A7_MOUSE Slc5a7 High affinity choline transporter 1 3.732e-07 0.32
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.307e-06 0.30
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 2.814e-06 0.96

Phenindione

CP2B6_HUMAN CYP2B6 Cytochrome P450 2B6 2.038e-45 0.37
P2RX7_MOUSE P2rx7 P2X purinoceptor 7 4.886e-26 0.83
DUS1_MOUSE Dusp1 Dual specificity protein phosphatase 1 2.07e-23 0.38
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.126e-21 0.35
CEL2A_RAT Cela2a Chymotrypsin-like elastase family member 2A 7.563e-20 0.32
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.292e-19 0.39
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.111e-17 0.39
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 1.11e-16 0.32
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.998e-15 0.32
ODP2_MYCTU dlaT Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 6.295e-14 0.32
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 1.965e-13 0.29
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 3.105e-11 0.45
AMPN_MOUSE Anpep Aminopeptidase N 6.343e-11 0.29
MEP2_YEAST MEP2 Ammonium transporter MEP2 4.084e-10 0.29
KCNA1_HUMAN KCNA1 Potassium voltage-gated channel subfamily A member 1 2.791e-09 0.29
KCNA4_HUMAN KCNA4 Potassium voltage-gated channel subfamily A member 4 2.791e-09 0.29
EST1_HUMAN CES1 Liver carboxylesterase 1 1.811e-08 0.39
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 2.037e-08 0.34
DOPO_HUMAN DBH Dopamine beta-hydroxylase 3.012e-08 0.31
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 8.352e-08 0.29
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 1.447e-07 0.33
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 1.637e-07 0.41
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.925e-07 0.35
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 5.506e-07 0.32
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 5.577e-07 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 5.927e-07 0.37
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 7.681e-07 0.39
DNAB_MYCTU dnaB Replicative DNA helicase 1.425e-06 0.45
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.673e-06 0.38
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.567e-06 0.68
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 6.484e-06 0.35
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 7.846e-06 0.29
WDR48_HUMAN WDR48 WD repeat-containing protein 48 9.607e-06 0.37

Brimonidine

G3HDX1_CRIGR Alpha-1B adrenergic receptor 4.238e-24 0.47
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 4.105e-18 0.47
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.152e-14 0.71
NISCH_RAT Nisch Nischarin 2.917e-13 0.39
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.276e-12 0.39
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.424e-11 0.71
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 8.44e-11 0.71
PI2R_HUMAN PTGIR Prostacyclin receptor 1.304e-10 0.36
NISCH_HUMAN NISCH Nischarin 9.623e-08 0.30