Results of Job: search_61e8b051-00d8-4cc3-b489-3578df6b736b

Query Target Key Target Name Description P-Value MaxTC

Tacrolimus

PP2BA_HUMAN PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 1.336e-224 1.00
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.986e-167 1.00
FKB1B_HUMAN FKBP1B Peptidyl-prolyl cis-trans isomerase FKBP1B 4.237e-70 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.214e-27 1.00
SF3B3_HUMAN SF3B3 Splicing factor 3B subunit 3 1.645e-26 1.00
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.665e-11 1.00
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 0.1887 1.00
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 0.4441 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9567 1.00
FKB1A_MOUSE Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 4.245e-115 0.42
FKBP4_HUMAN FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4 1.665e-15 0.88
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.92e-11 0.39

AZD8055

MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 3.363e-201 1.00
LST8_HUMAN MLST8 Target of rapamycin complex subunit LST8 2.369e-70 1.00
RPTOR_HUMAN RPTOR Regulatory-associated protein of mTOR 2.369e-70 1.00
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 3.641e-17 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 6.961e-13 1.00
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 1.222e-74 0.35
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 3.042e-14 0.33
PK3CA_BOVIN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5.121e-07 0.30
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 2.602e-06 0.30

Rocilinostat

HDAC3_HUMAN HDAC3 Histone deacetylase 3 4.525e-198 1.00
HDAC6_HUMAN HDAC6 Histone deacetylase 6 4.172e-187 1.00
HDAC1_HUMAN HDAC1 Histone deacetylase 1 3.976e-156 1.00
HDAC2_HUMAN HDAC2 Histone deacetylase 2 9.302e-106 1.00
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.356e-99 1.00
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.604e-97 1.00
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.657e-71 1.00
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.966e-111 0.66
Q9XYC7_PLAFA HDAC1 Histone deacetylase 8.724e-75 0.44
HDAC9_HUMAN HDAC9 Histone deacetylase 9 3.03e-69 0.54
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 6.74e-66 0.49
Q7K6A1_PLAF7 Histone deacetylase 2.293e-63 0.44
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 8.215e-60 0.36
HDA11_HUMAN HDAC11 Histone deacetylase 11 9.237e-60 0.54
HDAC7_HUMAN HDAC7 Histone deacetylase 7 1.428e-59 0.44
HDAC1_RAT Hdac1 Histone deacetylase 1 6.282e-58 0.56
HDAC5_HUMAN HDAC5 Histone deacetylase 5 1.791e-57 0.54
RCOR3_HUMAN RCOR3 REST corepressor 3 7.269e-55 0.44
Q9ZTP8_MAIZE hd1b Histone deacetylase 2.417e-52 0.44
HDAC1_MOUSE Hdac1 Histone deacetylase 1 4.521e-52 0.49
Q99P97_RAT Histone deacetylase 6 8.414e-45 0.36
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.579e-38 0.31
PA2A1_NAJMO Acidic phospholipase A2 CM-I 1.046e-36 0.29
CERT_HUMAN CERT1 Ceramide transfer protein 3.875e-36 0.29
TYTR_TRYCR TPR Trypanothione reductase 2.311e-35 0.35
ACES_TETCF ache Acetylcholinesterase 5.757e-35 0.36
HDAC4_HUMAN HDAC4 Histone deacetylase 4 3.307e-33 0.54
A5H660_SCHMA HDAC8 Histone deacetylase 8 5.218e-33 0.56
APAH_MYCRA aphA Acetylpolyamine amidohydrolase 1.574e-27 0.34
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 4.049e-26 0.30
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 2.199e-25 0.31
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 2.357e-21 0.32
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.048e-19 0.31
LIPL_HUMAN LPL Lipoprotein lipase 2.758e-19 0.31
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 9.178e-19 0.38
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.021e-18 0.30
COMT_PIG COMT Catechol O-methyltransferase 1.906e-18 0.31
CLPP_STAA8 clpP ATP-dependent Clp protease proteolytic subunit 2.139e-18 0.29
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 5.169e-18 0.39
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 8.819e-18 0.30
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.11e-16 0.39
ASAH1_HUMAN ASAH1 Acid ceramidase 1.11e-15 0.31
DRD1_PIG DRD1 D(1A) dopamine receptor 1.776e-15 0.39
DYR_MOUSE Dhfr Dihydrofolate reductase 2.22e-15 0.33
DXR_MYCS2 dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4.441e-15 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.61e-14 0.35
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 3.919e-14 0.31
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 6.461e-14 0.36
GLUC_HUMAN GCG Glucagon 7.749e-14 0.30
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.55e-13 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 2.586e-13 0.32
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.126e-13 0.39
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 6.449e-13 0.28
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.236e-12 0.30
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.94e-12 0.44
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.032e-11 0.32
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.512e-11 0.39
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 1.659e-11 0.31
AMP1_PLAFQ M1 family aminopeptidase 2.868e-11 0.34
LUCI_AQULA Luciferin 4-monooxygenase 5.096e-11 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 6.193e-11 0.44
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.408e-10 0.30
THAS_RAT Tbxas1 Thromboxane-A synthase 2.399e-10 0.35
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 2.648e-10 0.56
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 8.322e-10 0.34
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 9.516e-10 0.34
ECR_BOMMO EcR Ecdysone receptor 1.111e-09 0.32
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.27e-09 0.44
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.169e-09 0.39
TYSY_LACCA thyA Thymidylate synthase 2.412e-09 0.33
THAS_HUMAN TBXAS1 Thromboxane-A synthase 4.014e-09 0.37
DYN1_HUMAN DNM1 Dynamin-1 5.263e-09 0.32
MEP1B_HUMAN MEP1B Meprin A subunit beta 7.323e-09 0.30
LIPE_MOUSE Lipg Endothelial lipase 1.007e-08 0.31
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.573e-08 0.33
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2.863e-08 0.30
EGLN2_HUMAN EGLN2 Egl nine homolog 2 3.436e-08 0.34
AMPN_PIG ANPEP Aminopeptidase N 3.929e-08 0.40
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.592e-08 0.29
ACES_ELEEL ache Acetylcholinesterase 7.75e-08 0.36
CASP1_HUMAN CASP1 Caspase-1 9.719e-08 0.40
ACES_HUMAN ACHE Acetylcholinesterase 9.73e-08 0.36
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.223e-07 0.32
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.755e-07 0.38
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 1.879e-07 0.35
CHLE_HUMAN BCHE Cholinesterase 3.516e-07 0.36
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 7.208e-07 0.33
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 7.518e-07 0.29
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 8.53e-07 0.33
EST1_RABIT Liver carboxylesterase 1 1.225e-06 0.30
NEP_RABIT MME Neprilysin 1.556e-06 0.40
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.124e-06 0.28
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 2.488e-06 0.30
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 2.749e-06 0.32
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 3.573e-06 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.927e-06 0.39
GRIA4_RAT Gria4 Glutamate receptor 4 4.466e-06 0.33
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.592e-06 0.38
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 5.716e-06 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.157e-06 0.36
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 7.338e-06 0.30
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 7.69e-06 0.29
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 9.773e-06 0.32

CI994

HDAC1_HUMAN HDAC1 Histone deacetylase 1 9.294e-194 1.00
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.955e-134 1.00
HDAC2_HUMAN HDAC2 Histone deacetylase 2 3.675e-103 1.00
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 3.674e-114 0.43
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.334e-112 0.34
PRIO_SHEEP PRNP Major prion protein 1.092e-94 0.50
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.87e-67 0.40
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.194e-67 0.63
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.057e-64 0.39
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.646e-61 0.31
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 7.103e-58 0.47
Q38C41_TRYB2 Phosphotransferase 8.334e-52 0.37
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.039e-49 0.31
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.31e-48 0.43
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.141e-46 0.46
RXFP1_HUMAN RXFP1 Relaxin receptor 1 5.043e-46 0.40
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 7.831e-44 0.35
ACRO_HUMAN ACR Acrosin 6.628e-43 0.37
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 9.523e-43 0.34
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.379e-42 0.38
STXA_SHIDY stxA Shiga toxin subunit A 9.513e-42 0.48
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.054e-40 0.37
SENP1_HUMAN SENP1 Sentrin-specific protease 1 9.027e-39 0.41
EPHB_MYCTO Epoxide hydrolase B 1.11e-38 0.33
FABH_HAEIN fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.102e-37 0.30
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.406e-37 0.36
TNKS1_MOUSE Tnks Poly [ADP-ribose] polymerase tankyrase-1 2.707e-37 0.30
TNKS2_MOUSE Tnks2 Poly [ADP-ribose] polymerase tankyrase-2 2.707e-37 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.895e-36 0.34
THRB_MOUSE F2 Prothrombin 7.62e-36 0.28
NR1H4_HUMAN NR1H4 Bile acid receptor 2.503e-34 0.43
LUCI_AQULA Luciferin 4-monooxygenase 2.662e-34 0.35
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 9.707e-33 0.43
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.745e-32 0.38
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.148e-31 0.39
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 2.5e-31 0.36
TAAR1_RAT Taar1 Trace amine-associated receptor 1 3.899e-29 0.36
PSBA_MARPO psbA Photosystem II protein D1 1.981e-27 0.31
UROK_HUMAN PLAU Urokinase-type plasminogen activator 4.341e-27 0.38
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 6.987e-27 0.37
SENP7_HUMAN SENP7 Sentrin-specific protease 7 9.813e-27 0.42
V1AR_RAT Avpr1a Vasopressin V1a receptor 2.179e-26 0.35
V2R_RAT Avpr2 Vasopressin V2 receptor 3.848e-26 0.35
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 4.69e-26 0.32
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.381e-25 0.38
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.706e-25 0.47
FSHR_RAT Fshr Follicle-stimulating hormone receptor 6.731e-25 0.31
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.475e-24 0.33
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 2.289e-24 0.38
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 3.533e-24 0.40
UT1_RAT Slc14a1 Urea transporter 1 7.169e-24 0.34
A6QR73_RAT Gpr39 G protein-coupled receptor 39 3.077e-23 0.31
PLMN_MOUSE Plg Plasminogen 4.377e-23 0.28
UROK_RAT Plau Urokinase-type plasminogen activator 4.377e-23 0.28
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.269e-22 0.39
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.51e-22 0.36
SHH_MOUSE Shh Sonic hedgehog protein 2.817e-22 0.34
MYG_HUMAN MB Myoglobin 3.361e-22 0.43
LUCI_PHOPY Luciferin 4-monooxygenase 6.639e-22 0.38
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 9.761e-22 0.32
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.135e-21 0.31
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 2.846e-21 0.44
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 5.138e-21 0.48
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 6.1e-21 0.38
RCOR1_HUMAN RCOR1 REST corepressor 1 6.703e-21 0.40
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.019e-20 0.45
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.386e-20 0.40
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 1.541e-20 0.33
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.558e-20 0.32
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 1.765e-20 0.32
FA10_HUMAN F10 Coagulation factor X 1.956e-20 0.49
PPO2_AGABI PPO2 Polyphenol oxidase 2 7.085e-20 0.45
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 9.424e-20 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.17e-19 0.48
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.691e-19 0.38
Q25615_ONCVO Chitinase 7.612e-19 0.36
LIPL_HUMAN LPL Lipoprotein lipase 8.596e-19 0.30
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 9.734e-19 0.50
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.194e-18 0.36
RXFP2_HUMAN RXFP2 Relaxin receptor 2 2.576e-18 0.29
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.87e-18 0.45
PRTN3_HUMAN PRTN3 Myeloblastin 3.393e-18 0.37
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 4.478e-18 0.31
SMO_HUMAN SMO Smoothened homolog 4.526e-18 0.40
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 4.576e-18 0.43
UT2_RAT Slc14a2 Urea transporter 2 7.402e-18 0.34
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 8.52e-18 0.28
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.354e-17 0.33
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 1.882e-17 0.33
UREA_CANEN Urease 2.452e-17 0.38
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.879e-17 0.53
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.11e-16 0.32
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.11e-16 0.35
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 1.11e-16 0.34
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 2.22e-16 0.32
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.22e-16 0.53
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 2.22e-16 0.36
CYNT_HELPY cynT Carbonic anhydrase 3.331e-16 0.45
GPR35_HUMAN GPR35 G-protein coupled receptor 35 4.441e-16 0.36
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 4.441e-16 0.38
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 4.441e-16 0.31
PSBA_SPIOL psbA Photosystem II protein D1 5.551e-16 0.33
Q8MWR1_SPOFR USP Ultraspiracle protein 8.882e-16 0.29
Q8MWR2_SPOFR EcR Ecdysteroid receptor 8.882e-16 0.29
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.221e-15 0.36
ANDR_MOUSE Ar Androgen receptor 1.332e-15 0.39
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.332e-15 0.36
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.332e-15 0.36
NOX1_HUMAN NOX1 NADPH oxidase 1 1.887e-15 0.39
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 2.442e-15 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.554e-15 0.53
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.998e-15 0.48
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 3.997e-15 0.42
USP_DROME usp Protein ultraspiracle 4.441e-15 0.31
GRM5_MOUSE Grm5 Metabotropic glutamate receptor 5 6.106e-15 0.28
PLEC_HUMAN PLEC Plectin 6.772e-15 0.37
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.431e-14 0.42
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.598e-14 0.33
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 2.72e-14 0.40
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 9.504e-14 0.30
PLMN_HUMAN PLG Plasminogen 1.246e-13 0.37
KLK1_HUMAN KLK1 Kallikrein-1 1.527e-13 0.37
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.652e-13 0.49
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 2.173e-13 0.29
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 2.986e-13 0.29
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.99e-13 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 3.361e-13 0.33
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 4.819e-13 0.33
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 4.831e-13 0.38
UROK_MOUSE Plau Urokinase-type plasminogen activator 4.967e-13 0.28
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 5.927e-13 0.34
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 6.138e-13 0.35
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 6.678e-13 0.39
TRYP_PIG Trypsin 6.901e-13 0.37
BRPF1_HUMAN BRPF1 Peregrin 1.572e-12 0.33
ECR_DROME EcR Ecdysone receptor 2.039e-12 0.31
EST1_RABIT Liver carboxylesterase 1 2.548e-12 0.29
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 4.114e-12 0.30
GPR55_HUMAN GPR55 G-protein coupled receptor 55 4.456e-12 0.35
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 4.486e-12 0.35
CAH7_HUMAN CA7 Carbonic anhydrase 7 4.621e-12 0.43
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 4.652e-12 0.34
HDAC5_HUMAN HDAC5 Histone deacetylase 5 9.037e-12 0.38
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 9.838e-12 0.35
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.081e-11 0.44
TYRO_MOUSE Tyr Tyrosinase 1.339e-11 0.28
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 1.558e-11 0.33
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 4.075e-11 0.31
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 4.559e-11 0.34
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 5.408e-11 0.33
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 5.504e-11 0.31
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 5.941e-11 0.39
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 6.69e-11 0.40
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 7.368e-11 0.37
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 9.382e-11 0.43
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.172e-10 0.34
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 1.186e-10 0.34
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.307e-10 0.36
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.672e-10 0.42
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.244e-10 0.30
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.323e-10 0.43
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2.659e-10 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.71e-10 0.38
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 2.832e-10 0.29
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 2.921e-10 0.35
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 3.367e-10 0.35
TRY1_HUMAN PRSS1 Trypsin-1 3.413e-10 0.37
AURKA_HUMAN AURKA Aurora kinase A 4.088e-10 0.38
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 4.306e-10 0.34
CAH4_HUMAN CA4 Carbonic anhydrase 4 4.448e-10 0.34
TOP1_HUMAN TOP1 DNA topoisomerase 1 5.321e-10 0.44
H9B8T9_CAPHI CTSB Cathepsin B 5.4e-10 0.31
SENP8_HUMAN SENP8 Sentrin-specific protease 8 7.319e-10 0.33
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 8.129e-10 0.33
PIR_HUMAN PIR Pirin 1.045e-09 0.28
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.069e-09 0.32
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.08e-09 0.36
CAN_CANAL NCE103 Carbonic anhydrase 1.114e-09 0.33
VE1_HPV11 E1 Replication protein E1 1.391e-09 0.38
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 1.426e-09 0.35
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 2.039e-09 0.29
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.185e-09 0.38
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.596e-09 0.38
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.619e-09 0.48
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 3.009e-09 0.36
HDAC4_HUMAN HDAC4 Histone deacetylase 4 3.381e-09 0.47
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 4.271e-09 0.40
PCKGC_RAT Pck1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.722e-09 0.28
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 5.094e-09 0.30
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 5.187e-09 0.38
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 5.381e-09 0.32
TNFA_HUMAN TNF Tumor necrosis factor 5.774e-09 0.35
KLK7_HUMAN KLK7 Kallikrein-7 5.847e-09 0.33
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 6.929e-09 0.30
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 7.37e-09 0.38
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 9.198e-09 0.40
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 1.71e-08 0.33
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 1.728e-08 0.39
AURKB_HUMAN AURKB Aurora kinase B 1.91e-08 0.36
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.983e-08 0.42
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.191e-08 0.36
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.331e-08 0.36
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.389e-08 0.36
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 2.929e-08 0.29
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 3.452e-08 0.40
HDAC9_HUMAN HDAC9 Histone deacetylase 9 3.925e-08 0.38
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 4.168e-08 0.30
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 4.826e-08 0.33
PAG_BACAN pagA Protective antigen 4.905e-08 0.50
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 5.222e-08 0.32
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 5.789e-08 0.40
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.919e-08 0.38
CASP3_HUMAN CASP3 Caspase-3 6.41e-08 0.40
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.41e-08 0.38
EST1_HUMAN CES1 Liver carboxylesterase 1 7.082e-08 0.31
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 8.184e-08 0.34
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 8.523e-08 0.37
GPR39_HUMAN GPR39 G-protein coupled receptor 39 8.714e-08 0.31
E3UJZ5_SPOLI Ecdysone receptor 1.005e-07 0.31
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.008e-07 0.36
FACE2_HUMAN RCE1 CAAX prenyl protease 2 1.066e-07 0.31
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.188e-07 0.31
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.19e-07 0.38
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.292e-07 0.40
ECR_BOMMO EcR Ecdysone receptor 1.43e-07 0.31
WNT3A_MOUSE Wnt3a Protein Wnt-3a 1.436e-07 0.30
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.757e-07 0.34
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 2.069e-07 0.37
MITF_HUMAN MITF Microphthalmia-associated transcription factor 2.396e-07 0.38
HSF1_MOUSE Hsf1 Heat shock factor protein 1 2.565e-07 0.37
IL6_HUMAN IL6 Interleukin-6 2.68e-07 0.28
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 2.681e-07 0.33
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 3.016e-07 0.34
RECA_MYCTU recA Protein RecA 4.6e-07 0.40
NEUR3_HUMAN NEU3 Sialidase-3 4.709e-07 0.33
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 5.261e-07 0.36
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 5.414e-07 0.30
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 6.001e-07 0.43
ATM_HUMAN ATM Serine-protein kinase ATM 6.619e-07 0.37
CAH4_BOVIN CA4 Carbonic anhydrase 4 7.949e-07 0.43
STRP_STRP1 ska Streptokinase A 8.714e-07 0.42
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 9.501e-07 0.31
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 9.956e-07 0.32
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 9.964e-07 0.38
Q25270_LEIDO beta-tubulin Beta-tubulin 1.069e-06 0.31
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.093e-06 0.37
HSF1_HUMAN HSF1 Heat shock factor protein 1 1.205e-06 0.30
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 1.288e-06 0.33
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.323e-06 0.29
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 1.402e-06 0.34
LYOX_HUMAN LOX Protein-lysine 6-oxidase 1.618e-06 0.32
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.625e-06 0.40
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 2.025e-06 0.41
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 2.083e-06 0.35
PA21B_HUMAN PLA2G1B Phospholipase A2 2.094e-06 0.39
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 2.124e-06 0.28
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.251e-06 0.32
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.26e-06 0.29
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.306e-06 0.33
EST2_HUMAN CES2 Cocaine esterase 2.849e-06 0.29
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.849e-06 0.29
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 3.027e-06 0.32
AA1R_RAT Adora1 Adenosine receptor A1 3.331e-06 0.33
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.885e-06 0.43
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 3.924e-06 0.32
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 4.202e-06 0.33
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 4.544e-06 0.33
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 4.575e-06 0.33
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 4.657e-06 0.32
Q03732_HBV HBcAg Capsid protein 4.778e-06 0.32
WDR5_HUMAN WDR5 WD repeat-containing protein 5 5.704e-06 0.33
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 6.249e-06 0.32
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 6.334e-06 0.32
CXCR2_HUMAN CXCR2 C-X-C chemokine receptor type 2 6.569e-06 0.31
LIMK1_HUMAN LIMK1 LIM domain kinase 1 6.578e-06 0.33
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 6.599e-06 0.33
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 6.874e-06 0.48
MINK1_HUMAN MINK1 Misshapen-like kinase 1 7.05e-06 0.32
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 7.126e-06 0.31
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 7.196e-06 0.29
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 7.585e-06 0.40
AGP1_YEAST AGP1 General amino acid permease AGP1 8.09e-06 0.28
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 8.215e-06 0.32
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 8.269e-06 0.34
TLR1_MOUSE Tlr1 Toll-like receptor 1 9.636e-06 0.29
TLR2_MOUSE Tlr2 Toll-like receptor 2 9.636e-06 0.29
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 9.749e-06 0.31

Citarinostat

HDAC6_HUMAN HDAC6 Histone deacetylase 6 8.68e-143 1.00
HDAC3_HUMAN HDAC3 Histone deacetylase 3 4.291e-140 0.84
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.748e-113 0.84
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.14e-79 0.56
HDAC2_HUMAN HDAC2 Histone deacetylase 2 5.011e-70 0.84
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.034e-69 0.84
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.707e-63 0.84
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.891e-52 0.43
HDAC9_HUMAN HDAC9 Histone deacetylase 9 2.921e-51 0.47
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 3.184e-51 0.36
RCOR3_HUMAN RCOR3 REST corepressor 3 3.737e-47 0.38
HDAC1_MOUSE Hdac1 Histone deacetylase 1 4.401e-47 0.43
HDAC7_HUMAN HDAC7 Histone deacetylase 7 4.048e-44 0.38
HDAC5_HUMAN HDAC5 Histone deacetylase 5 9e-44 0.47
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.009e-42 0.84
Q99P97_RAT Histone deacetylase 6 1.474e-39 0.31
Q9XYC7_PLAFA HDAC1 Histone deacetylase 2.643e-37 0.40
Q9ZTP8_MAIZE hd1b Histone deacetylase 3.606e-36 0.38
HDA11_HUMAN HDAC11 Histone deacetylase 11 2.284e-35 0.47
HDAC1_RAT Hdac1 Histone deacetylase 1 3.993e-32 0.48
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.077e-26 0.48
APAH_MYCRA aphA Acetylpolyamine amidohydrolase 7.498e-24 0.29
Q7K6A1_PLAF7 Histone deacetylase 2.07e-23 0.38
HDAC4_HUMAN HDAC4 Histone deacetylase 4 2.459e-23 0.47
ACES_TETCF ache Acetylcholinesterase 6.538e-23 0.32
DYR_MOUSE Dhfr Dihydrofolate reductase 3.331e-16 0.30
DRD1_PIG DRD1 D(1A) dopamine receptor 4.108e-15 0.34
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 6.517e-14 0.30
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 3.445e-11 0.34
PTPRO_HUMAN PTPRO Receptor-type tyrosine-protein phosphatase O 1.415e-10 0.28
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 2.006e-10 0.38
TYTR_TRYCR TPR Trypanothione reductase 3.911e-10 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.587e-10 0.37
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 2.501e-09 0.31
THAS_RAT Tbxas1 Thromboxane-A synthase 4.84e-09 0.35
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 5.992e-09 0.48
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.204e-09 0.35
TYSY_LACCA thyA Thymidylate synthase 1.447e-08 0.30
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.838e-08 0.28
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.597e-07 0.34
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.828e-07 0.29
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 2.439e-07 0.35
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.66e-07 0.37
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.618e-06 0.32
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.158e-06 0.39
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 2.524e-06 0.32
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 6.008e-06 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 8.201e-06 0.38

Lenalidomide

IKZF1_HUMAN IKZF1 DNA-binding protein Ikaros 1.288e-130 1.00
CRBN_HUMAN CRBN Protein cereblon 2.331e-108 1.00
AMPN_MOUSE Anpep Aminopeptidase N 1.647e-10 0.28
VACHT_TETCF Vesicular acetylcholine transporter 2.651e-10 0.31
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 5.272e-07 0.29

Idasanutlin

MDM2_HUMAN MDM2 E3 ubiquitin-protein ligase Mdm2 8.671e-130 1.00
FA11_HUMAN F11 Coagulation factor XI 9.321e-21 0.35
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 6.407e-19 0.30
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.11e-16 0.35
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 4.996e-15 0.30
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 6.163e-11 0.30
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 9.769e-11 0.31
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 1.536e-10 0.30
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.784e-10 0.30
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.267e-07 0.38

Tofacitinib

JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 8.113e-129 1.00
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 2.9e-124 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 7.023e-109 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.202e-89 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 7.681e-86 1.00
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 4.629e-39 1.00
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.735e-32 1.00
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 2.976e-21 1.00
DMPK_HUMAN DMPK Myotonin-protein kinase 1.043e-20 1.00
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.016e-19 1.00
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 7.622e-19 1.00
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 4.603e-18 1.00
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 4.603e-18 1.00
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.319e-17 1.00
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 1.144e-14 1.00
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.144e-14 1.00
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 1.896e-13 1.00
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 3.137e-13 1.00
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 6.986e-13 1.00
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 9.469e-13 1.00
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.589e-12 1.00
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 6.82e-11 1.00
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 8.563e-11 1.00
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 8.563e-11 1.00
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.016e-10 1.00
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 4.372e-09 1.00
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 1.125e-08 1.00
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 4.421e-08 1.00
KPCD_HUMAN PRKCD Protein kinase C delta type 2.654e-07 1.00
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 2.622e-06 1.00
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 1.045e-05 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 7.476e-05 1.00
KPCG_HUMAN PRKCG Protein kinase C gamma type 8.099e-05 1.00
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 8.586e-05 1.00
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 0.0002763 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 0.0004626 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 0.0004676 1.00
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 0.0004964 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 0.001452 1.00
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 0.00149 1.00
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.003192 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 0.003337 1.00
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 0.003768 1.00
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 0.01655 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 0.03918 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 0.3824 1.00
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 4.288e-25 0.36
CECR2_HUMAN CECR2 Cat eye syndrome critical region protein 2 4.831e-25 0.29
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 1.011e-24 0.36
CCR10_MOUSE Ccr10 C-C chemokine receptor type 10 4.219e-21 0.29
TAF1_HUMAN TAF1 Transcription initiation factor TFIID subunit 1 5.024e-21 0.29
CCR10_HUMAN CCR10 C-C chemokine receptor type 10 2.776e-15 0.29
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 5.329e-15 0.33
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 3.487e-12 0.33
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 1.916e-10 0.33
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 5.09e-10 0.37
BRD9_HUMAN BRD9 Bromodomain-containing protein 9 9.752e-10 0.29
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 2.371e-09 0.34
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 9.077e-09 0.33
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 9.077e-09 0.33
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 9.077e-09 0.33
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 9.077e-09 0.33
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 2.354e-08 0.33
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 5.451e-08 0.33
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 5.451e-08 0.33
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 5.451e-08 0.33
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1.151e-07 0.33
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 4.114e-07 0.33
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 4.114e-07 0.33
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 7.125e-07 0.33
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 7.125e-07 0.33
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.661e-06 0.33
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 2.744e-06 0.51
KPCT_HUMAN PRKCQ Protein kinase C theta type 2.983e-06 0.33
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 4.216e-06 0.33
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 4.216e-06 0.33
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 6.069e-06 0.33
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 6.522e-06 0.30
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 8.523e-06 0.33
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 8.523e-06 0.33
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 8.523e-06 0.33

ZSTK474

PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.121e-127 1.00
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1.11e-81 1.00
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 4.985e-62 1.00
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 4.626e-59 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 3.502e-53 1.00
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 4.334e-33 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5.002e-26 1.00
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 1.121e-22 1.00
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 1.479e-19 1.00
XRCC5_HUMAN XRCC5 X-ray repair cross-complementing protein 5 1.102e-37 0.30
XRCC6_HUMAN XRCC6 X-ray repair cross-complementing protein 6 1.102e-37 0.30
NK2R_MESAU TACR2 Substance-K receptor 1.11e-16 0.31
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 2.887e-15 0.36
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 6.217e-15 0.30
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 3.322e-12 0.36
HMOX2_RAT Hmox2 Heme oxygenase 2 9.315e-12 0.30
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 5.4e-10 0.36
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 8.31e-09 0.32
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 1.867e-08 0.30
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 1.278e-07 0.29
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 1.59e-07 0.29
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.19e-06 0.37
Q9BPW0_HUMAN PPP5C Serine/threonine-protein phosphatase 2.774e-06 0.36
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 3.168e-06 0.28
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 5.901e-06 0.38

Podophyllotoxin

VE2_HPV1 E2 Regulatory protein E2 2.9e-124 1.00
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.119e-34 1.00
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 3.853e-10 1.00
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.145e-06 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 0.0003032 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.03137 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.05509 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.08166 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 0.8069 1.00
EDNRB_MOUSE Ednrb Endothelin receptor type B 5.104e-54 0.33
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.15e-33 0.33
Q9XSW7_PIG Phosphodiesterase 1.287e-20 0.33
T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 2.22e-16 0.31
EDNRA_HUMAN EDNRA Endothelin-1 receptor 7.772e-16 0.39
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.98e-13 0.51
EDNRB_HUMAN EDNRB Endothelin receptor type B 1.415e-12 0.33
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.219e-12 0.51
ITF2_HUMAN TCF4 Transcription factor 4 1.215e-11 0.31
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.383e-11 0.28
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.965e-10 0.30
TF_HUMAN F3 Tissue factor 1.165e-07 0.32
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.261e-07 0.51
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.942e-06 0.33

Pracinostat (SB-939)

HDAC1_HUMAN HDAC1 Histone deacetylase 1 6.875e-121 1.00
HDAC8_HUMAN HDAC8 Histone deacetylase 8 6.773e-80 1.00
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.783e-64 1.00
HDAC9_HUMAN HDAC9 Histone deacetylase 9 2.509e-53 1.00
HDAC5_HUMAN HDAC5 Histone deacetylase 5 2.668e-53 1.00
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.013e-52 1.00
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.372e-39 1.00
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.854e-39 1.00
HDAC2_HUMAN HDAC2 Histone deacetylase 2 4.034e-36 1.00
HDAC4_HUMAN HDAC4 Histone deacetylase 4 4.98e-28 1.00
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.725e-19 1.00
Q9ZTP8_MAIZE hd1b Histone deacetylase 1.854e-72 0.34
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.966e-66 0.34
AGTRA_RAT Agtr1 Type-1A angiotensin II receptor 2.079e-43 0.38
HDAC1_MOUSE Hdac1 Histone deacetylase 1 9.112e-26 0.32
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 3.957e-20 0.36
A8K2H7_HUMAN C3AR1 Complement component 3a receptor 1, isoform CRA_a 1.518e-18 0.36
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 9.312e-18 0.34
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 6.661e-16 0.38
OPRM_MACMU OPRM1 Mu-type opioid receptor 3.22e-15 0.38
TLR7_HUMAN TLR7 Toll-like receptor 7 1.085e-13 0.32
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.588e-13 0.28
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 7.311e-13 0.32
ICMT_HUMAN ICMT Protein-S-isoprenylcysteine O-methyltransferase 6.322e-11 0.31
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.441e-10 0.33
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.98e-10 0.32
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 7.417e-09 0.29
TLR8_HUMAN TLR8 Toll-like receptor 8 5.484e-08 0.33
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 9.762e-08 0.36

Chidamide

HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.338e-119 1.00
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.122e-77 1.00
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.25e-11 1.00
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.158e-108 0.44
HDAC1_MOUSE Hdac1 Histone deacetylase 1 8.288e-64 0.50
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 5.864e-61 0.58
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.143e-53 0.51
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 3.154e-46 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.244e-42 0.34
SENP2_HUMAN SENP2 Sentrin-specific protease 2 1.796e-41 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.119e-37 0.34
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 7.498e-37 0.44
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.32e-36 0.42
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.1e-24 0.37
T23O_RAT Tdo2 Tryptophan 2,3-dioxygenase 1.577e-23 0.33
NAMPT_RAT Nampt Nicotinamide phosphoribosyltransferase 2.063e-23 0.29
STABP_HUMAN STAMBP STAM-binding protein 3.231e-22 0.34
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 2.124e-20 0.36
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 7.938e-20 0.34
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 1.071e-19 0.31
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 4.167e-18 0.30
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.133e-17 0.31
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.829e-13 0.66
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 7.242e-13 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 8.591e-13 0.40
BKRB2_CAVPO BDKRB2 B2 bradykinin receptor 1.268e-12 0.32
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 1.458e-12 0.33
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.078e-11 0.30
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.877e-11 0.29
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 8.191e-11 0.29
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 6.133e-10 0.41
BKRB2_HUMAN BDKRB2 B2 bradykinin receptor 1.668e-09 0.32
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.635e-09 0.29
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 4.722e-09 0.29
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 4.724e-09 0.40
ITA4_HUMAN ITGA4 Integrin alpha-4 5.313e-09 0.34
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 8.071e-09 0.38
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.043e-08 0.29
Q76353_9HIV1 Integrase 1.114e-08 0.34
ITB1_HUMAN ITGB1 Integrin beta-1 1.15e-08 0.34
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.209e-08 0.31
STXA_SHIDY stxA Shiga toxin subunit A 1.428e-08 0.30
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.039e-08 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.582e-08 0.40
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 5.258e-08 0.35
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 5.323e-08 0.40
HDAC9_HUMAN HDAC9 Histone deacetylase 9 6.406e-08 0.34
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 1.447e-07 0.29
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.724e-07 0.34
CYSP_PLAFA Trophozoite cysteine proteinase 2.243e-07 0.32
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 2.733e-07 0.32
HPSE_HUMAN HPSE Heparanase 3.761e-07 0.30
HDA11_HUMAN HDAC11 Histone deacetylase 11 4.747e-07 0.44
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 6.39e-07 0.28
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 6.582e-07 0.35
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 7.518e-07 0.29
PIM3_HUMAN PIM3 Serine/threonine-protein kinase pim-3 1.057e-06 0.30
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.079e-06 0.33
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.182e-06 0.29
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 1.604e-06 0.36
AMP1_PLAFQ M1 family aminopeptidase 2.114e-06 0.33
LDLR_HUMAN LDLR Low-density lipoprotein receptor 2.444e-06 0.29
PRIO_SHEEP PRNP Major prion protein 2.631e-06 0.29
HDAC5_HUMAN HDAC5 Histone deacetylase 5 2.908e-06 0.40
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 3.848e-06 0.30
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 5.415e-06 0.29
Q76129_9HIV1 gag Structural capsid protein 5.692e-06 0.29
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.696e-06 0.35
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 8.279e-06 0.28
ACOD_HUMAN SCD Acyl-CoA desaturase 9.237e-06 0.38

Dypyridamole

PRUN1_HUMAN PRUNE1 Exopolyphosphatase PRUNE1 1.953e-105 1.00
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 9.297e-65 1.00
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.735e-32 1.00
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.235e-09 1.00
O40947_HHV8 ORF 73 1.702e-08 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.06e-05 1.00
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 2.06e-05 1.00
PDE2A_HUMAN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 0.07089 1.00
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 0.5085 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 0.9991 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9994 1.00
LICH_HUMAN LIPA Lysosomal acid lipase/cholesteryl ester hydrolase 2.048e-25 0.32

Cerdulatinib

JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 4.743e-97 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 1.195e-89 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 2.207e-50 1.00
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 6.638e-154 0.56
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 8.144e-143 0.41
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 3.993e-111 0.42
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 6.59e-109 0.45
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 1.274e-106 0.49
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 6.427e-104 0.49
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 5.269e-96 0.45
ALK_HUMAN ALK ALK tyrosine kinase receptor 4.274e-83 0.50
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 2.679e-68 0.49
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 2.048e-61 0.42
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 9.288e-54 0.45
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 9e-53 0.45
C11B2_MOUSE Cyp11b2 Cytochrome P450 11B2, mitochondrial 9.643e-49 0.32
FAK1_HUMAN PTK2 Focal adhesion kinase 1 2.843e-47 0.41
TBK1_MOUSE Tbk1 Serine/threonine-protein kinase TBK1 9.812e-47 0.39
INSR_HUMAN INSR Insulin receptor 5.712e-43 0.41
CCNH_HUMAN CCNH Cyclin-H 8.126e-41 0.36
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.377e-40 0.47
CCNA2_HUMAN CCNA2 Cyclin-A2 7.649e-40 0.42
CCR7_HUMAN CCR7 C-C chemokine receptor type 7 4.474e-39 0.31
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 1.033e-38 0.50
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 7.103e-38 0.40
LYAM3_HUMAN SELP P-selectin 8.991e-38 0.41
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 9.236e-38 0.38
INSR_RAT Insr Insulin receptor 1.377e-35 0.28
AURKA_HUMAN AURKA Aurora kinase A 2.177e-33 0.42
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 2.36e-32 0.38
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 2.761e-32 0.40
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.158e-30 0.34
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5.731e-30 0.40
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 5.884e-30 0.40
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 2.287e-29 0.44
AURKB_HUMAN AURKB Aurora kinase B 2.451e-29 0.42
TTK_HUMAN TTK Dual specificity protein kinase TTK 5.945e-29 0.43
GPR6_HUMAN GPR6 G-protein coupled receptor 6 1.064e-28 0.33
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.677e-28 0.35
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 1.836e-28 0.35
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 3.766e-27 0.85
CCNA1_HUMAN CCNA1 Cyclin-A1 1.313e-26 0.38
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 3.985e-26 0.35
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 9.381e-26 0.43
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 1.432e-25 0.35
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.451e-25 0.47
WEE1_HUMAN WEE1 Wee1-like protein kinase 1.882e-25 0.42
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 2.415e-25 0.30
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 2.981e-25 0.29
MP2K1_MOUSE Map2k1 Dual specificity mitogen-activated protein kinase kinase 1 3.065e-25 0.41
H9YX08_MACMU CCR6 C-C chemokine receptor type 6 3.865e-25 0.31
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 6.236e-25 0.29
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 1.598e-23 0.42
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 2.296e-23 0.38
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 2.296e-23 0.38
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.78e-23 0.50
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 3.373e-23 0.47
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 3.886e-23 0.35
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 6.027e-23 0.35
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 7.448e-23 0.41
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 7.466e-23 0.40
CD63_HUMAN CD63 CD63 antigen 8.614e-23 0.29
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 2.617e-22 0.40
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 2.804e-22 0.35
LCK_HUMAN LCK Tyrosine-protein kinase Lck 3.69e-22 0.43
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 5.461e-22 0.35
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 5.21e-21 0.41
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 5.317e-21 0.35
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 6.446e-21 0.34
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1.103e-20 0.37
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 2.073e-20 0.29
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.114e-20 0.50
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 3.488e-20 0.39
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.732e-20 0.43
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 6.856e-20 0.40
CCNT1_HUMAN CCNT1 Cyclin-T1 7.88e-20 0.36
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.232e-19 0.39
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 1.265e-19 0.40
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 1.936e-19 0.33
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 4.019e-19 0.35
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 4.701e-19 0.38
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 5.29e-19 0.40
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 1.927e-18 0.40
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 2.502e-18 0.40
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 2.575e-18 0.40
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 2.711e-18 0.40
PRIO_SHEEP PRNP Major prion protein 4.132e-18 0.30
CDC2H_PLAF7 CRK2 Cell division control protein 2 homolog 4.799e-18 0.35
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 5.359e-18 0.31
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 6.09e-18 0.35
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 6.631e-18 0.42
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 7.673e-18 0.40
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 7.864e-18 0.47
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 8.816e-18 0.40
ST32C_HUMAN STK32C Serine/threonine-protein kinase 32C 9.056e-18 0.28
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.069e-17 0.40
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 2.008e-17 0.29
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.527e-17 0.42
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 3.345e-17 0.29
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 3.724e-17 0.35
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 4.852e-17 0.34
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 1.11e-16 0.31
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.11e-16 0.35
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.11e-16 0.40
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 1.11e-16 0.29
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 2.22e-16 0.40
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 2.22e-16 0.35
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 3.331e-16 0.40
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 4.441e-16 0.35
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.441e-16 0.35
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 4.441e-16 0.34
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 5.551e-16 0.37
MET_HUMAN MET Hepatocyte growth factor receptor 6.661e-16 0.40
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 6.661e-16 0.40
RON_HUMAN MST1R Macrophage-stimulating protein receptor 9.992e-16 0.40
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 1.11e-15 0.38
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 1.332e-15 0.39
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 2.22e-15 0.39
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 2.331e-15 0.29
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 2.554e-15 0.34
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 3.22e-15 0.35
ACVR1_HUMAN ACVR1 Activin receptor type-1 3.553e-15 0.40
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 5.995e-15 0.40
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 1.055e-14 0.37
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 1.055e-14 0.33
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 1.144e-14 0.29
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1.21e-14 0.37
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 1.499e-14 0.29
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.499e-14 0.29
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.854e-14 0.30
DMPK_HUMAN DMPK Myotonin-protein kinase 1.965e-14 0.35
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 2.065e-14 0.35
PDE6A_BOVIN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 3.086e-14 0.29
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 3.164e-14 0.40
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 3.342e-14 0.40
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 3.741e-14 0.40
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 6.484e-14 0.35
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 6.928e-14 0.34
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 7.15e-14 0.34
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 7.638e-14 0.29
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 9.415e-14 0.35
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 9.415e-14 0.35
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 1.011e-13 0.37
FER_HUMAN FER Tyrosine-protein kinase Fer 1.147e-13 0.35
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 1.286e-13 0.35
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.209e-13 0.37
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 2.388e-13 0.35
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 3.217e-13 0.29
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 3.217e-13 0.29
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 3.217e-13 0.29
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 3.217e-13 0.29
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 3.397e-13 0.40
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 3.577e-13 0.39
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 3.794e-13 0.35
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 4.439e-13 0.40
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 5.88e-13 0.35
GP119_MOUSE Gpr119 Glucose-dependent insulinotropic receptor 6.285e-13 0.33
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 7.102e-13 0.34
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 7.981e-13 0.42
BTK_HUMAN BTK Tyrosine-protein kinase BTK 9.099e-13 0.43
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 1.155e-12 0.29
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 1.155e-12 0.29
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 1.433e-12 0.35
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 1.802e-12 0.35
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.89e-12 0.35
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 3.382e-12 0.40
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 4.548e-12 0.39
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 5.611e-12 0.34
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 6.289e-12 0.29
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 6.563e-12 0.40
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 6.667e-12 0.35
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 6.764e-12 0.29
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 7.251e-12 0.35
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 7.759e-12 0.37
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 9.385e-12 0.40
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.02e-11 0.29
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.02e-11 0.29
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 1.034e-11 0.35
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 1.088e-11 0.40
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 1.264e-11 0.32
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.338e-11 0.37
ALK_MOUSE Alk ALK tyrosine kinase receptor 1.437e-11 0.28
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 1.437e-11 0.28
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.487e-11 0.40
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 1.741e-11 0.35
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.334e-11 0.35
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 2.551e-11 0.31
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.605e-11 0.29
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.605e-11 0.29
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 2.956e-11 0.32
GP119_HUMAN GPR119 Glucose-dependent insulinotropic receptor 2.982e-11 0.35
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 3.181e-11 0.34
GYRB_MYCSM gyrB DNA gyrase subunit B 3.327e-11 0.30
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 3.581e-11 0.37
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 3.595e-11 0.29
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 4.628e-11 0.34
MK12_HUMAN MAPK12 Mitogen-activated protein kinase 12 5.922e-11 0.34
INSRR_HUMAN INSRR Insulin receptor-related protein 6.132e-11 0.29
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 6.132e-11 0.29
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 6.446e-11 0.35
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 7.134e-11 0.35
KPCT_HUMAN PRKCQ Protein kinase C theta type 7.406e-11 0.40
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 9.367e-11 0.43
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.192e-10 0.37
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 1.345e-10 0.29
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 1.55e-10 0.40
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.644e-10 0.30
FRK_HUMAN FRK Tyrosine-protein kinase FRK 2.273e-10 0.35
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 2.772e-10 0.29
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 3.665e-10 0.35
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 3.798e-10 0.37
AURKC_HUMAN AURKC Aurora kinase C 4.11e-10 0.30
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 4.759e-10 0.34
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 4.885e-10 0.29
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 5.412e-10 0.29
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 5.412e-10 0.29
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 5.462e-10 0.35
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 5.918e-10 0.35
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 7.541e-10 0.29
O97467_PLAFA ht1 Hexose transporter 1 9.219e-10 0.48
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 9.976e-10 0.34
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 1.007e-09 0.29
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 1.007e-09 0.29
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 1.116e-09 0.31
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 1.172e-09 0.35
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 1.51e-09 0.31
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.788e-09 0.41
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1.795e-09 0.29
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 1.795e-09 0.29
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 1.795e-09 0.29
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.795e-09 0.29
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 2.334e-09 0.35
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 3.081e-09 0.29
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 3.081e-09 0.29
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.639e-09 0.39
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 4.654e-09 0.40
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 4.864e-09 0.28
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 5.109e-09 0.29
LSS_RAT Lss Lanosterol synthase 5.885e-09 0.30
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 6.143e-09 0.32
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 6.997e-09 0.39
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 8.216e-09 0.29
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 8.487e-09 0.40
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 8.719e-09 0.40
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.306e-09 0.40
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 9.993e-09 0.35
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 9.993e-09 0.35
O61059_LEIME LmGT2 Glucose transporter 1.045e-08 0.48
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.285e-08 0.29
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1.285e-08 0.29
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.285e-08 0.29
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.285e-08 0.29
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 1.322e-08 0.29
AVR2A_HUMAN ACVR2A Activin receptor type-2A 1.751e-08 0.28
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 1.751e-08 0.28
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 1.751e-08 0.28
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 1.751e-08 0.28
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 1.865e-08 0.35
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 1.958e-08 0.29
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1.958e-08 0.29
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 1.958e-08 0.29
KPCG_HUMAN PRKCG Protein kinase C gamma type 1.978e-08 0.35
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.828e-08 0.29
LIMK1_HUMAN LIMK1 LIM domain kinase 1 2.856e-08 0.38
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.305e-08 0.48
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 3.355e-08 0.35
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 3.628e-08 0.35
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 3.985e-08 0.29
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 4.086e-08 0.35
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 4.255e-08 0.29
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 4.255e-08 0.29
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 4.255e-08 0.29
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.546e-08 0.42
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 6.087e-08 0.29
HCK_HUMAN HCK Tyrosine-protein kinase HCK 6.98e-08 0.31
TGM1_HUMAN TGM1 Protein-glutamine gamma-glutamyltransferase K 7.16e-08 0.30
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 7.73e-08 0.35
REV1_HUMAN REV1 DNA repair protein REV1 8.352e-08 0.29
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 8.554e-08 0.29
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 8.554e-08 0.29
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 8.554e-08 0.29
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 8.554e-08 0.29
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.064e-07 0.35
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 1.183e-07 0.29
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1.183e-07 0.29
SYK_HUMAN KARS1 Lysine--tRNA ligase 1.244e-07 0.37
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.288e-07 0.37
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.324e-07 0.28
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.324e-07 0.28
MYO3A_HUMAN MYO3A Myosin-IIIa 1.324e-07 0.28
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.324e-07 0.28
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 1.61e-07 0.29
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.162e-07 0.29
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.162e-07 0.29
TEC_HUMAN TEC Tyrosine-protein kinase Tec 2.268e-07 0.28
ACV1B_HUMAN ACVR1B Activin receptor type-1B 2.865e-07 0.29
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.865e-07 0.29
BRDT_HUMAN BRDT Bromodomain testis-specific protein 2.99e-07 0.38
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 2.994e-07 0.28
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.994e-07 0.28
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.994e-07 0.28
MYO3B_HUMAN MYO3B Myosin-IIIb 2.994e-07 0.28
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 2.994e-07 0.28
E2AK2_HUMAN EIF2AK2 Interferon-induced, double-stranded RNA-activated protein kinase 3.292e-07 0.29
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 3.717e-07 0.35
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 3.75e-07 0.29
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 3.824e-07 0.37
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 4.905e-07 0.29
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 4.905e-07 0.29
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 4.905e-07 0.29
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 4.905e-07 0.29
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 4.931e-07 0.34
JUN_HUMAN JUN Transcription factor AP-1 4.931e-07 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 4.977e-07 0.29
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 6.218e-07 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 6.689e-07 0.28
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 6.76e-07 0.35
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 7.512e-07 0.42
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 8.511e-07 0.35
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 1.03e-06 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.136e-06 0.33
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 1.166e-06 0.28
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 1.235e-06 0.29
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.235e-06 0.29
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.451e-06 0.34
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1.653e-06 0.31
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 1.683e-06 0.29
LGUL_HUMAN GLO1 Lactoylglutathione lyase 1.698e-06 0.30
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 1.804e-06 0.35
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.832e-06 0.37
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 2.07e-06 0.28
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 2.924e-06 0.39
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 3.264e-06 0.37
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 3.308e-06 0.29
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.347e-06 0.40
AVR2B_HUMAN ACVR2B Activin receptor type-2B 3.477e-06 0.28
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 3.477e-06 0.28
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 3.95e-06 0.29
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 4.208e-06 0.37
F13A_HUMAN F13A1 Coagulation factor XIII A chain 4.399e-06 0.30
DPOL_VACCW POL DNA polymerase 4.865e-06 0.29
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 5.155e-06 0.29
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 5.537e-06 0.29
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 5.537e-06 0.29
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 6.503e-06 0.29
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 7.112e-06 0.29
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 7.112e-06 0.29
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 7.328e-06 0.37
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.629e-06 0.34
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 7.796e-06 0.35
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 8.387e-06 0.29
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 8.404e-06 0.34

Apitolisib

PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 9.645e-69 1.00
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 5.036e-58 1.00
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 4.405e-39 1.00
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 2.685e-37 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.298e-32 1.00
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 5.586e-28 1.00
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5.047e-25 1.00
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 1.182e-12 1.00
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 5.944e-12 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 4.014e-08 1.00
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 0.02186 1.00
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 0.8615 1.00
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 1.958e-59 0.56
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 5.891e-34 0.35
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.559e-13 0.35
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 6.382e-11 0.35
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.39e-10 0.40
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 3.924e-09 0.35
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 5.692e-09 0.35
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 8.292e-09 0.35
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 5.7e-08 0.35
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 6.195e-08 0.35
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.307e-07 0.35
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.307e-07 0.35
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 1.521e-07 0.40
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 4.049e-07 0.35
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 4.049e-07 0.35
PK3CA_BOVIN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 4.542e-07 0.31
HDAC5_HUMAN HDAC5 Histone deacetylase 5 2.271e-06 0.40
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 2.381e-06 0.35
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.894e-06 0.40
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 8.923e-06 0.35
HDAC1_HUMAN HDAC1 Histone deacetylase 1 9.535e-06 0.42

Baricitinib

JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 2.243e-67 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 2.901e-63 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 4.935e-54 1.00
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.013e-48 1.00
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 1.551e-39 0.31
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 9.45e-22 0.49
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 5.794e-18 0.31
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 1.338e-17 0.49
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 4.885e-15 0.49
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 4.657e-13 0.49
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 7.13e-13 0.35
SYT_YERPE thrS Threonine--tRNA ligase 7.13e-13 0.35
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 8.579e-13 0.31
DMPK_HUMAN DMPK Myotonin-protein kinase 9.933e-13 0.49
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 1.413e-12 0.49
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.413e-12 0.49
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.413e-12 0.49
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.413e-12 0.49
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 3.929e-12 0.49
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 5.729e-12 0.49
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 1.328e-11 0.49
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 1.967e-11 0.49
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 1.967e-11 0.49
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 1.967e-11 0.49
TPX2_HUMAN TPX2 Targeting protein for Xklp2 2.335e-11 0.33
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 3.938e-11 0.49
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 3.938e-11 0.49
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 5.887e-11 0.49
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.011e-10 0.31
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 1.047e-10 0.49
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 1.052e-10 0.49
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 3.818e-10 0.49
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.818e-10 0.49
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 8.54e-10 0.49
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 8.54e-10 0.49
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 1.155e-08 0.49
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 1.155e-08 0.49
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 1.969e-08 0.49
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 3.236e-08 0.49
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 3.236e-08 0.49
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 3.236e-08 0.49
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 4.149e-08 0.49
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 5.146e-08 0.49
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 5.146e-08 0.49
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 7.948e-08 0.49
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 7.948e-08 0.49
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 1.195e-07 0.49
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1.755e-07 0.49
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.755e-07 0.49
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 1.755e-07 0.49
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 2.522e-07 0.49
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 2.522e-07 0.49
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 4.913e-07 0.49
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 4.913e-07 0.49
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 6.684e-07 0.49
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 8.955e-07 0.49
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 1.008e-06 0.49
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 1.008e-06 0.49
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 1.183e-06 0.49
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1.183e-06 0.49
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 1.183e-06 0.49
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 3.192e-06 0.49
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 4.104e-06 0.49
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 4.932e-06 0.49
GRK5_HUMAN GRK5 G protein-coupled receptor kinase 5 7.656e-06 0.49
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 8.9e-06 0.49
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.9e-06 0.49

Adavosertib

WEE1_HUMAN WEE1 Wee1-like protein kinase 2.023e-61 1.00
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 2.239e-48 1.00
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.227e-47 1.00
FAK1_HUMAN PTK2 Focal adhesion kinase 1 2.92e-47 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 6.783e-39 1.00
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 2.401e-37 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.433e-25 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.282e-24 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 9.566e-11 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.735e-10 1.00
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 5.503e-10 1.00
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 2.642e-09 1.00
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 5.346e-09 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.881e-08 1.00
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 3.323e-08 1.00
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 8.31e-08 1.00
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 6.687e-07 1.00
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 1.423e-06 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1.809e-06 1.00
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2.056e-06 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 4.174e-06 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 7.391e-06 1.00
KPCT_HUMAN PRKCQ Protein kinase C theta type 6.946e-05 1.00
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 0.0003056 1.00
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 0.0007504 1.00
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 0.001188 1.00
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 1.107e-143 0.43
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 2.266e-91 0.42
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 2.444e-60 0.43
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 5.408e-57 0.43
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 2.533e-48 0.44
MYT1_HUMAN MYT1 Myelin transcription factor 1 1.432e-45 0.29
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 2.119e-45 0.42
INSR_RAT Insr Insulin receptor 3.222e-39 0.31
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 3.255e-38 0.46
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 2.379e-34 0.35
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 9.317e-34 0.31
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 2.087e-32 0.46
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 2.583e-30 0.42
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 2.583e-30 0.42
ALK_HUMAN ALK ALK tyrosine kinase receptor 2.784e-30 0.44
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 5.803e-30 0.45
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.58e-29 0.31
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 2.884e-27 0.31
EGFR_HUMAN EGFR Epidermal growth factor receptor 3.268e-27 0.44
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 1.425e-26 0.30
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 7.133e-25 0.39
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.711e-24 0.45
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 2.08e-23 0.41
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 3.733e-23 0.46
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 3.813e-23 0.39
CCNA2_HUMAN CCNA2 Cyclin-A2 9.023e-23 0.42
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 1.333e-22 0.31
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 4.108e-22 0.39
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 5.012e-22 0.31
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 6.819e-22 0.31
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 8.239e-21 0.42
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 1.695e-20 0.31
ST32C_HUMAN STK32C Serine/threonine-protein kinase 32C 1.535e-19 0.31
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 2.079e-19 0.30
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 7.357e-19 0.42
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 8.53e-19 0.31
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 3.629e-18 0.39
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.959e-18 0.31
AVR2A_HUMAN ACVR2A Activin receptor type-2A 4.459e-17 0.31
INSR_HUMAN INSR Insulin receptor 5.536e-17 0.39
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 1.11e-16 0.31
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.11e-16 0.31
CCNA1_HUMAN CCNA1 Cyclin-A1 5.551e-16 0.42
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 7.772e-16 0.31
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 1.11e-15 0.31
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.11e-15 0.31
BLK_MOUSE Blk Tyrosine-protein kinase Blk 5.218e-15 0.28
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 5.551e-15 0.31
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 5.551e-15 0.31
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.343e-14 0.45
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 1.366e-14 0.31
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.366e-14 0.31
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 1.721e-14 0.31
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.721e-14 0.31
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 3.02e-14 0.31
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 3.02e-14 0.31
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 3.02e-14 0.31
DMPK_HUMAN DMPK Myotonin-protein kinase 3.209e-14 0.31
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 4.23e-14 0.42
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 1.202e-13 0.31
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 1.202e-13 0.31
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.713e-13 0.31
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 1.995e-13 0.42
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 2.608e-13 0.46
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 3.112e-13 0.45
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 4.149e-13 0.31
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 4.508e-13 0.28
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 4.731e-13 0.39
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 5.89e-13 0.31
ALK_MOUSE Alk ALK tyrosine kinase receptor 1.076e-12 0.31
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 1.076e-12 0.31
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.268e-12 0.31
AURKA_HUMAN AURKA Aurora kinase A 1.814e-12 0.44
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 1.882e-12 0.42
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 1.995e-12 0.31
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 1.995e-12 0.31
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.773e-12 0.38
AVR2B_HUMAN ACVR2B Activin receptor type-2B 2.922e-12 0.31
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 3.498e-12 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.498e-12 0.31
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 4.521e-12 0.37
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 4.747e-12 0.31
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 5.978e-12 0.31
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 5.978e-12 0.31
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 8.828e-12 0.31
INSRR_HUMAN INSRR Insulin receptor-related protein 8.828e-12 0.31
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 9.943e-12 0.31
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 9.943e-12 0.31
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 1.614e-11 0.31
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 1.899e-11 0.39
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 2.064e-11 0.31
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 2.064e-11 0.31
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.212e-11 0.36
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.564e-11 0.31
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.564e-11 0.31
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 2.75e-11 0.39
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.392e-11 0.36
ACV1B_HUMAN ACVR1B Activin receptor type-1B 3.989e-11 0.31
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 3.989e-11 0.31
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 4.512e-11 0.31
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 5.075e-11 0.39
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 5.94e-11 0.30
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 6.089e-11 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 6.089e-11 0.31
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.499e-11 0.39
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 7.965e-11 0.37
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 8.626e-11 0.37
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 9.301e-11 0.31
MARK1_HUMAN MARK1 Serine/threonine-protein kinase MARK1 9.301e-11 0.31
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 9.301e-11 0.31
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 9.301e-11 0.31
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 9.334e-11 0.31
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 1.82e-10 0.31
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 1.883e-10 0.31
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 2.765e-10 0.39
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 3.401e-10 0.31
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 3.401e-10 0.31
TBK1_MOUSE Tbk1 Serine/threonine-protein kinase TBK1 3.472e-10 0.30
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.946e-10 0.31
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 6.098e-10 0.31
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 6.098e-10 0.31
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 6.659e-10 0.31
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 7.567e-10 0.31
ACVR1_HUMAN ACVR1 Activin receptor type-1 8.945e-10 0.37
M3K10_HUMAN MAP3K10 Mitogen-activated protein kinase kinase kinase 10 1.03e-09 0.31
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 1.054e-09 0.31
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1.128e-09 0.36
HCK_HUMAN HCK Tyrosine-protein kinase HCK 1.3e-09 0.36
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.761e-09 0.31
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.761e-09 0.31
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 1.761e-09 0.31
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 1.761e-09 0.31
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.848e-09 0.31
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 2.3e-09 0.41
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 2.567e-09 0.30
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 2.579e-09 0.37
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 2.737e-09 0.31
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 2.737e-09 0.31
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 2.737e-09 0.31
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 2.854e-09 0.31
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 2.854e-09 0.31
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.854e-09 0.31
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 2.854e-09 0.31
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 3.19e-09 0.31
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.428e-09 0.44
O97467_PLAFA ht1 Hexose transporter 1 3.609e-09 0.42
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 4.137e-09 0.31
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 4.137e-09 0.31
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 4.434e-09 0.30
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 4.502e-09 0.31
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 4.502e-09 0.31
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 5.213e-09 0.31
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.321e-09 0.31
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.107e-09 0.36
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 8.111e-09 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 9.705e-09 0.36
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 1.042e-08 0.31
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 1.042e-08 0.31
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 1.042e-08 0.31
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 1.14e-08 0.32
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.285e-08 0.46
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 1.428e-08 0.30
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.444e-08 0.28
GAK_HUMAN GAK Cyclin-G-associated kinase 1.494e-08 0.31
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 1.534e-08 0.31
RON_HUMAN MST1R Macrophage-stimulating protein receptor 1.805e-08 0.37
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 1.83e-08 0.31
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 2.072e-08 0.31
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 2.215e-08 0.31
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.215e-08 0.31
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.304e-08 0.30
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 2.548e-08 0.31
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 2.548e-08 0.31
MYO3A_HUMAN MYO3A Myosin-IIIa 2.548e-08 0.31
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 2.548e-08 0.31
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 2.885e-08 0.28
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 3.143e-08 0.31
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 3.91e-08 0.30
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 4.164e-08 0.45
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 4.387e-08 0.31
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 5.221e-08 0.43
BRDT_HUMAN BRDT Bromodomain testis-specific protein 5.224e-08 0.44
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 6.032e-08 0.31
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 6.268e-08 0.31
MYO3B_HUMAN MYO3B Myosin-IIIb 6.268e-08 0.31
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 6.268e-08 0.31
TEC_HUMAN TEC Tyrosine-protein kinase Tec 1.006e-07 0.31
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.044e-07 0.42
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.145e-07 0.39
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 1.277e-07 0.31
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 1.279e-07 0.31
O61059_LEIME LmGT2 Glucose transporter 1.362e-07 0.42
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 1.483e-07 0.31
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1.498e-07 0.31
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.889e-07 0.31
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 1.889e-07 0.31
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 2.034e-07 0.31
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 2.041e-07 0.30
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 2.041e-07 0.30
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 2.041e-07 0.30
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 2.041e-07 0.30
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 2.357e-07 0.31
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 2.401e-07 0.37
CSK_HUMAN CSK Tyrosine-protein kinase CSK 2.722e-07 0.31
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 2.807e-07 0.31
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 2.807e-07 0.31
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 3.963e-07 0.31
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 5.286e-07 0.31
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 5.831e-07 0.37
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 6.604e-07 0.39
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 7.538e-07 0.30
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 9.36e-07 0.31
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 9.454e-07 0.37
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 1.066e-06 0.45
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.316e-06 0.30
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.391e-06 0.31
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.658e-06 0.37
PRIO_SHEEP PRNP Major prion protein 1.777e-06 0.30
SHH_MOUSE Shh Sonic hedgehog protein 2.115e-06 0.33
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 2.192e-06 0.38
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 2.384e-06 0.31
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 2.391e-06 0.37
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 3.111e-06 0.31
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 3.321e-06 0.31
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 3.469e-06 0.30
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 3.469e-06 0.30
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 3.743e-06 0.31
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 3.748e-06 0.31
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 3.902e-06 0.31
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 5.271e-06 0.31
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 5.303e-06 0.30
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 5.303e-06 0.30
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 5.45e-06 0.29
TTK_HUMAN TTK Dual specificity protein kinase TTK 5.66e-06 0.36
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 6.622e-06 0.37
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 7.02e-06 0.31
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 9.427e-06 0.31

BX795

CGAS_HUMAN CGAS Cyclic GMP-AMP synthase 1.089e-50 1.00
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 3.441e-46 1.00
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 4.063e-45 1.00
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 8.404e-06 1.00
TBK1_MOUSE Tbk1 Serine/threonine-protein kinase TBK1 2.165e-130 0.42
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 3.847e-32 0.84
KISSR_HUMAN KISS1R KiSS-1 receptor 6.129e-29 0.32
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 3.812e-26 0.33
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 4.608e-24 0.35
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 1.972e-23 0.31
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 5.979e-20 0.34
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.451e-18 0.33
BCR_HUMAN BCR Breakpoint cluster region protein 2.139e-18 0.29
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 7.809e-18 0.35
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 4.53e-14 0.36
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 1.052e-13 0.30
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.743e-13 0.34
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 2.579e-13 0.30
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.55e-12 0.35
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.633e-12 0.35
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 2.95e-12 0.29
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 4.484e-12 0.32
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 1.145e-11 0.30
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.149e-11 0.32
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 1.305e-11 0.32
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.967e-11 0.33
PDPK1_HUMAN PDPK1 3-phosphoinositide-dependent protein kinase 1 3.265e-11 0.84
ALK_HUMAN ALK ALK tyrosine kinase receptor 3.801e-11 0.45
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 3.845e-11 0.30
MET_HUMAN MET Hepatocyte growth factor receptor 1.66e-10 0.45
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 2.867e-10 0.30
ITB2_HUMAN ITGB2 Integrin beta-2 3.031e-10 0.30
CDN1A_HUMAN CDKN1A Cyclin-dependent kinase inhibitor 1 3.253e-10 0.34
ANM3_HUMAN PRMT3 Protein arginine N-methyltransferase 3 4.335e-10 0.29
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 4.811e-10 0.30
INSR_HUMAN INSR Insulin receptor 7.762e-10 0.33
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 1.033e-09 0.30
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 1.469e-09 0.30
BLK_HUMAN BLK Tyrosine-protein kinase Blk 3.719e-09 0.30
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 5.728e-09 0.30
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 9.651e-09 0.29
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 9.761e-09 0.31
ITAL_HUMAN ITGAL Integrin alpha-L 1.035e-08 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.112e-08 0.43
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.133e-08 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.267e-08 0.34
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.817e-08 0.30
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 1.817e-08 0.30
TXK_HUMAN TXK Tyrosine-protein kinase TXK 3.819e-08 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.845e-08 0.35
TEC_HUMAN TEC Tyrosine-protein kinase Tec 4.187e-08 0.34
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 4.908e-08 0.30
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 4.908e-08 0.30
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 4.908e-08 0.30
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 4.908e-08 0.30
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 1.168e-07 0.30
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.374e-07 0.36
DRD1_PIG DRD1 D(1A) dopamine receptor 1.835e-07 0.32
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 1.913e-07 0.34
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 2.507e-07 0.30
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 2.507e-07 0.30
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 2.507e-07 0.30
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 2.507e-07 0.30
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 2.507e-07 0.30
SRPK2_HUMAN SRPK2 SRSF protein kinase 2 2.507e-07 0.30
STK11_HUMAN STK11 Serine/threonine-protein kinase STK11 2.507e-07 0.30
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 2.507e-07 0.30
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 3.826e-07 0.34
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 4.948e-07 0.30
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 4.948e-07 0.30
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 5.238e-07 0.34
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 5.914e-07 0.33
ICAM1_HUMAN ICAM1 Intercellular adhesion molecule 1 7.915e-07 0.30
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 9.101e-07 0.30
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 9.101e-07 0.30
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.578e-06 0.30
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.578e-06 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.578e-06 0.30
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.874e-06 0.30
BRDT_HUMAN BRDT Bromodomain testis-specific protein 1.898e-06 0.30
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 2.023e-06 0.32
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.283e-06 0.30
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 2.601e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.601e-06 0.30
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.601e-06 0.30
DPOL_VACCW POL DNA polymerase 2.965e-06 0.31
NOS1_RAT Nos1 Nitric oxide synthase, brain 3.122e-06 0.38
AURKA_HUMAN AURKA Aurora kinase A 3.173e-06 0.51
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 3.764e-06 0.30
CCNT1_HUMAN CCNT1 Cyclin-T1 3.814e-06 0.35
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 4.105e-06 0.30
INSRR_HUMAN INSRR Insulin receptor-related protein 4.105e-06 0.30
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 4.105e-06 0.30
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 4.105e-06 0.30
MYLK4_HUMAN MYLK4 Myosin light chain kinase family member 4 4.105e-06 0.30
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 5.067e-06 0.30
KLK7_HUMAN KLK7 Kallikrein-7 5.141e-06 0.33
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 5.438e-06 0.43
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 6.241e-06 0.30
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 6.241e-06 0.30
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 6.241e-06 0.30
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 6.241e-06 0.30
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 6.241e-06 0.30
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 6.28e-06 0.30
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 6.876e-06 0.32
STABP_HUMAN STAMBP STAM-binding protein 8.695e-06 0.29
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 9.182e-06 0.30
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.182e-06 0.30

VS5584

PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 4.457e-49 1.00
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 9.484e-22 1.00
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 6.572e-19 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.01e-14 1.00
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 6.472e-43 0.52
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1.325e-32 0.34
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 3.101e-21 0.47
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 6.146e-19 0.52
ADK_RAT Adk Adenosine kinase 6.217e-15 0.33
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 2.351e-13 0.47
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 4.271e-13 0.38
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 7.759e-09 0.35
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 8.311e-09 0.35
NK2R_MESAU TACR2 Substance-K receptor 9.353e-09 0.32
CD63_HUMAN CD63 CD63 antigen 2.316e-08 0.29
J7IFZ2_STRPY Dihydrofolate reductase 6.499e-07 0.29
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 6.024e-06 0.35

Molibresib

BRD4_HUMAN BRD4 Bromodomain-containing protein 4 5.792e-32 1.00
BRD2_HUMAN BRD2 Bromodomain-containing protein 2 6.144e-29 1.00
BRD3_HUMAN BRD3 Bromodomain-containing protein 3 8.336e-28 1.00
TSPOB_HUMAN TSPO Putative peripheral benzodiazepine receptor-related protein 9.397e-62 0.49
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 3.56e-37 0.29
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.076e-23 0.30
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.093e-20 0.32
HSC82_YEAST HSC82 ATP-dependent molecular chaperone HSC82 2.22e-16 0.32
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.882e-16 0.33
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 3.664e-15 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 4.219e-15 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 3.997e-14 0.32
FFAR1_MOUSE Ffar1 Free fatty acid receptor 1 6.259e-12 0.29
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 7.655e-12 0.33
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.694e-11 0.31
CNR1_RAT Cnr1 Cannabinoid receptor 1 1.435e-10 0.34
ANO2_HUMAN ANO2 Anoctamin-2 1.621e-10 0.28
SUH_HUMAN RBPJ Recombining binding protein suppressor of hairless 9.629e-09 0.30
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.09e-08 0.33
S6A15_HUMAN SLC6A15 Sodium-dependent neutral amino acid transporter B(0)AT2 4.067e-08 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 9.328e-08 0.29
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 1.367e-07 0.32
CCKAR_RAT Cckar Cholecystokinin receptor type A 2.946e-07 0.42
TSPO_RAT Tspo Translocator protein 3.214e-07 0.37
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 4.481e-07 0.29
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.593e-06 0.31
Q95PM0_TRYBR rhodesain Cysteine protease 1.79e-06 0.33
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.536e-06 0.32
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 3.461e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 5.124e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 6.605e-06 0.29
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.278e-06 0.30

NVP-BEP800

HS90B_HUMAN HSP90AB1 Heat shock protein HSP 90-beta 7.321e-30 1.00
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 5.27e-43 0.36
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 2.832e-31 0.36
MYT1_HUMAN MYT1 Myelin transcription factor 1 2.847e-23 0.29
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.11e-16 0.38
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.11e-16 0.36
BLK_MOUSE Blk Tyrosine-protein kinase Blk 4.441e-15 0.29
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.553e-14 0.38
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 3.922e-13 0.29
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.772e-12 0.34
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 6.152e-10 0.34
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 7.541e-10 0.29
NORA_STAAU norA Quinolone resistance protein NorA 1.911e-09 0.31
AVR2A_HUMAN ACVR2A Activin receptor type-2A 1.322e-08 0.29
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.322e-08 0.29
LYAM2_HUMAN SELE E-selectin 2.197e-08 0.38
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 1.031e-07 0.29
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.438e-07 0.34
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.489e-07 0.29
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.89e-07 0.30
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.362e-07 0.29
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.362e-07 0.29
KMO_HUMAN KMO Kynurenine 3-monooxygenase 2.718e-07 0.34
DPOL_VACCW POL DNA polymerase 3.078e-07 0.36
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 4.905e-07 0.29
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 9.396e-07 0.29
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 1.372e-06 0.30
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 2.202e-06 0.38
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 2.732e-06 0.31
AVR2B_HUMAN ACVR2B Activin receptor type-2B 2.849e-06 0.29
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.849e-06 0.29
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 7.112e-06 0.29

BIIB021

TRAP1_HUMAN TRAP1 Heat shock protein 75 kDa, mitochondrial 2.012e-25 1.00
ENPL_CANLF HSP90B1 Endoplasmin 4.449e-17 1.00
ENPL_HUMAN HSP90B1 Endoplasmin 2.758e-09 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.329e-09 1.00
HS90B_HUMAN HSP90AB1 Heat shock protein HSP 90-beta 0.0006031 1.00
MURI_ENTFA murI Glutamate racemase 1.707e-24 0.33
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 2.22e-16 0.31
DYR_ECOLI folA Dihydrofolate reductase 6.228e-14 0.30
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 7.329e-09 0.31
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.445e-07 0.31

Bemcentinib

UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 1.02e-23 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 6.735e-09 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 5.94e-08 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.54e-05 1.00
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 9.085e-05 1.00
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 0.006972 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 0.04408 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 0.09252 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 0.182 1.00
AURKA_HUMAN AURKA Aurora kinase A 0.224 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 0.3051 1.00
ALK_HUMAN ALK ALK tyrosine kinase receptor 0.5998 1.00
AURKB_HUMAN AURKB Aurora kinase B 0.7729 1.00
MET_HUMAN MET Hepatocyte growth factor receptor 0.8036 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1 1.00
DPO3_STAAU polC DNA polymerase III PolC-type 7.125e-33 0.31
HRH4_MOUSE Hrh4 Histamine H4 receptor 2.22e-16 0.33
FAK1_HUMAN PTK2 Focal adhesion kinase 1 5.323e-12 0.39
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 2.699e-11 0.30
HRH4_RAT Hrh4 Histamine H4 receptor 5.946e-08 0.33
TOP3_BACSU topB DNA topoisomerase 3 1.302e-06 0.32

Afuresertib

AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 2.03e-19 1.00
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 4.948e-09 1.00
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 3.712e-06 1.00
ITB7_HUMAN ITGB7 Integrin beta-7 4.265e-50 0.39
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 9.573e-26 0.32
Q9TU16_CANLF PTGER4 Prostaglandin E receptor 4 7.459e-25 0.31
CATL2_HUMAN CTSV Cathepsin L2 6.614e-21 0.33
ITA4_HUMAN ITGA4 Integrin alpha-4 2.79e-20 0.39
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 7.687e-20 0.50
STIM1_RAT Stim1 Stromal interaction molecule 1 1.6e-17 0.33
ITB1_HUMAN ITGB1 Integrin beta-1 1.11e-16 0.36
CCNT1_HUMAN CCNT1 Cyclin-T1 1.11e-15 0.34
STIM1_HUMAN STIM1 Stromal interaction molecule 1 5.407e-14 0.33
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 9.909e-13 0.33
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 1.078e-12 0.33
Q6DMN0_TOXGO CPL Cathepsin L 6.69e-10 0.29
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 3.249e-08 0.35
SYUA_HUMAN SNCA Alpha-synuclein 5.397e-08 0.33
PGLD_CAMJE pglD UDP-N-acetylbacillosamine N-acetyltransferase 3.46e-07 0.29
CLK2_MOUSE Clk2 Dual specificity protein kinase CLK2 7.499e-07 0.29
CLK4_MOUSE Clk4 Dual specificity protein kinase CLK4 7.499e-07 0.29
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 4.828e-06 0.36
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 6.544e-06 0.31
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 7.482e-06 0.35
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 9.784e-06 0.39

Cycloheximide (Actidione)

RL19A_YEAST RPL19A 60S ribosomal protein L19-A 1.344e-18 1.00
COT2_HUMAN NR2F2 COUP transcription factor 2 2.159e-13 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 0.0001072 1.00
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 0.0009905 1.00
XBP1_HUMAN XBP1 X-box-binding protein 1 0.005858 1.00
O97467_PLAFA ht1 Hexose transporter 1 0.007577 1.00
O61059_LEIME LmGT2 Glucose transporter 0.007937 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.01621 1.00
HSF1_MOUSE Hsf1 Heat shock factor protein 1 0.01897 1.00
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 0.02212 1.00

Apabetalone

BRDT_HUMAN BRDT Bromodomain testis-specific protein 1.337e-10 1.00
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 0.0007857 1.00
BRD2_HUMAN BRD2 Bromodomain-containing protein 2 0.002061 1.00
BRD3_HUMAN BRD3 Bromodomain-containing protein 3 0.002581 1.00
CDN1A_HUMAN CDKN1A Cyclin-dependent kinase inhibitor 1 2.86e-57 0.37
BGLR_HUMAN GUSB Beta-glucuronidase 1.957e-36 0.38
PDE4B_RAT Pde4b cAMP-specific 3',5'-cyclic phosphodiesterase 4B 8.093e-20 0.32
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 5.178e-17 0.36
A3KMY8_BOVIN GUSB Beta-glucuronidase 2.442e-15 0.38
PEBB_HUMAN CBFB Core-binding factor subunit beta 3.166e-12 0.31
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 1.116e-11 0.33
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 1.119e-11 0.38
PDE5A_RAT Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase 5.601e-11 0.30
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 6.388e-10 0.38
C3SWJ7_ECOLX thyA Thymidylate synthase 9.78e-10 0.34
TYSY_HUMAN TYMS Thymidylate synthase 5.475e-08 0.34
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.197e-07 0.38
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 2.982e-07 0.32

Upadacitinib

JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 3.323e-08 1.00
HGFL_HUMAN MST1 Hepatocyte growth factor-like protein 3.028e-18 0.29
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.302e-12 0.35
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 2.381e-12 0.32
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.376e-08 0.40
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 7.766e-08 0.40

Everolimus

MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 0.08786 1.00
FKB1A_MOUSE Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 2.873e-239 0.89
PP2BA_HUMAN PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 7.51e-114 0.39
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.095e-100 0.89
FKB1B_HUMAN FKBP1B Peptidyl-prolyl cis-trans isomerase FKBP1B 2.165e-63 0.89
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 4.238e-25 0.89
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 4.894e-25 0.89
SF3B3_HUMAN SF3B3 Splicing factor 3B subunit 3 3.241e-10 0.37
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 4.821e-10 0.89
FKBP4_HUMAN FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4 4.793e-07 0.38

Entinostat

HDAC1_HUMAN HDAC1 Histone deacetylase 1 8.32e-176 0.78
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.132e-138 0.58
HDAC3_HUMAN HDAC3 Histone deacetylase 3 4.474e-107 0.78
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.46e-94 0.78
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.645e-68 0.36
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 3.955e-57 0.58
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 1.152e-55 0.31
HDAC1_MOUSE Hdac1 Histone deacetylase 1 6.393e-53 0.51
KLK8_HUMAN KLK8 Kallikrein-8 2.522e-52 0.32
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.241e-49 0.69
KLK4_HUMAN KLK4 Kallikrein-4 5.201e-48 0.32
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.886e-45 0.36
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.489e-45 0.38
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 7.449e-41 0.40
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 5.702e-40 0.32
KLK2_HUMAN KLK2 Kallikrein-2 4.342e-35 0.32
MIP_LEGPN mip Outer membrane protein MIP 1.784e-31 0.30
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 3.49e-30 0.32
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 3.106e-29 0.36
KLKB1_HUMAN KLKB1 Plasma kallikrein 4.881e-29 0.41
THER_BACTH npr Thermolysin 1.513e-28 0.31
PDS_SYNE7 pds 15-cis-phytoene desaturase 2.481e-27 0.32
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.569e-26 0.36
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.243e-24 0.29
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 1.026e-23 0.42
NR1H4_HUMAN NR1H4 Bile acid receptor 5.181e-23 0.38
ACOD_HUMAN SCD Acyl-CoA desaturase 2.135e-21 0.41
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 7.935e-21 0.40
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 8.408e-21 0.35
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 4e-20 0.36
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 6.189e-20 0.35
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.829e-19 0.83
KLK1_HUMAN KLK1 Kallikrein-1 4.597e-19 0.37
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.028e-18 0.49
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 1.062e-17 0.35
LYOX_HUMAN LOX Protein-lysine 6-oxidase 1.736e-17 0.32
ISPH_AQUAE ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1.11e-16 0.32
STXA_SHIDY stxA Shiga toxin subunit A 1.11e-16 0.32
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.11e-16 0.35
INHBA_MOUSE Inhba Inhibin beta A chain 4.441e-16 0.31
A5H660_SCHMA HDAC8 Histone deacetylase 8 1.221e-15 0.31
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.665e-15 0.29
PRTN3_HUMAN PRTN3 Myeloblastin 1.887e-15 0.32
RCOR1_HUMAN RCOR1 REST corepressor 1 4.441e-15 0.34
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 7.438e-15 0.28
IL6_HUMAN IL6 Interleukin-6 3.297e-14 0.30
FA10_HUMAN F10 Coagulation factor X 4.463e-14 0.39
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 9.681e-14 0.34
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.553e-13 0.39
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.714e-13 0.30
HDAC5_HUMAN HDAC5 Histone deacetylase 5 1.89e-13 0.43
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.257e-13 0.30
LDLR_HUMAN LDLR Low-density lipoprotein receptor 5.602e-13 0.33
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 7.853e-13 0.44
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.224e-12 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.816e-12 0.30
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 4.689e-12 0.35
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 5.28e-12 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.204e-12 0.38
RS27_HUMAN RPS27 40S ribosomal protein S27 7.53e-12 0.32
ACHP_LYMST Acetylcholine-binding protein 9.255e-12 0.32
STABP_HUMAN STAMBP STAM-binding protein 1.095e-11 0.35
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.302e-11 0.38
Q72874_9HIV1 pol Pol polyprotein 2.115e-11 0.43
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 2.479e-11 0.31
AMPL_PIG LAP3 Cytosol aminopeptidase 2.517e-11 0.33
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.038e-11 0.28
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 3.542e-11 0.30
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 3.989e-11 0.30
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.05e-11 0.33
CYSP_TRYCR Cruzipain 4.512e-11 0.36
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.513e-11 0.31
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 4.959e-11 0.30
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 5.168e-11 0.30
SSPA_STAAU sspA Glutamyl endopeptidase 5.659e-11 0.29
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 6.878e-11 0.29
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 7.066e-11 0.33
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.285e-10 0.38
FA12_HUMAN F12 Coagulation factor XII 1.354e-10 0.29
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 1.798e-10 0.35
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.982e-10 0.29
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 3.074e-10 0.35
HDAC7_HUMAN HDAC7 Histone deacetylase 7 6.828e-10 0.43
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 8.439e-10 0.34
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.087e-09 0.28
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.118e-09 0.31
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.133e-09 0.58
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.823e-09 0.30
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 2.037e-09 0.32
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 2.293e-09 0.34
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.015e-09 0.28
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 5.15e-09 0.29
NSMA_RAT Smpd2 Sphingomyelin phosphodiesterase 2 6.132e-09 0.35
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 6.499e-09 0.53
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 6.72e-09 0.40
SCAF_HHV11 UL26 Capsid scaffolding protein 7.167e-09 0.33
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 9.785e-09 0.32
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.031e-08 0.32
HDAC9_HUMAN HDAC9 Histone deacetylase 9 1.23e-08 0.43
AMPN_HUMAN ANPEP Aminopeptidase N 1.267e-08 0.33
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.703e-08 0.28
VHL_HUMAN VHL von Hippel-Lindau disease tumor suppressor 1.894e-08 0.31
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 2.73e-08 0.29
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 2.812e-08 0.33
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 3.1e-08 0.28
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 4.516e-08 0.28
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 4.629e-08 0.33
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.886e-08 0.34
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 5.084e-08 0.32
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 5.858e-08 0.41
HDAC4_HUMAN HDAC4 Histone deacetylase 4 5.982e-08 0.43
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 6.452e-08 0.36
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 9.381e-08 0.33
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.072e-07 0.39
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.728e-07 0.32
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.129e-07 0.29
GPR35_HUMAN GPR35 G-protein coupled receptor 35 2.511e-07 0.30
PA_I34A1 PA Polymerase acidic protein 2.814e-07 0.31
CYNT_HELPY cynT Carbonic anhydrase 3.03e-07 0.33
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.333e-07 0.53
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 4.004e-07 0.33
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 4.234e-07 0.30
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 4.31e-07 0.37
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 4.383e-07 0.32
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.396e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.396e-07 0.29
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 6.243e-07 0.29
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 6.499e-07 0.29
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 6.586e-07 0.35
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 6.906e-07 0.43
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 7.413e-07 0.40
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 7.766e-07 0.33
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.016e-06 0.28
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.102e-06 0.31
GALR3_HUMAN GALR3 Galanin receptor type 3 1.17e-06 0.34
CATB_BOVIN CTSB Cathepsin B 1.249e-06 0.30
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.327e-06 0.47
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.51e-06 0.36
NEP_HUMAN MME Neprilysin 1.601e-06 0.32
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.67e-06 0.29
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.683e-06 0.29
PRIO_SHEEP PRNP Major prion protein 1.7e-06 0.30
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.827e-06 0.28
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 1.942e-06 0.31
KLK5_HUMAN KLK5 Kallikrein-5 1.959e-06 0.29
STE24_YEAST STE24 CAAX prenyl protease 1 1.989e-06 0.46
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 2.025e-06 0.31
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.064e-06 0.35
CASP3_HUMAN CASP3 Caspase-3 2.562e-06 0.37
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 2.721e-06 0.29
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 3.802e-06 0.36
CATB_HUMAN CTSB Cathepsin B 3.807e-06 0.39
PNPH_RAT Pnp Purine nucleoside phosphorylase 3.847e-06 0.29
PAG_BACAN pagA Protective antigen 3.91e-06 0.37
LUCI_AQULA Luciferin 4-monooxygenase 4.478e-06 0.30
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 4.91e-06 0.38
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 5.28e-06 0.36
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 5.557e-06 0.29
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.109e-06 0.33
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 6.215e-06 0.39
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 6.785e-06 0.28
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 6.802e-06 0.35
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 6.914e-06 0.29
PLEC_HUMAN PLEC Plectin 8.037e-06 0.29
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 8.327e-06 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 8.338e-06 0.32
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 8.548e-06 0.38
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 8.822e-06 0.30
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 9.909e-06 0.31

LY3023414

ATM_HUMAN ATM Serine-protein kinase ATM 2.688e-136 0.41
MTOR_MOUSE Mtor Serine/threonine-protein kinase mTOR 1.272e-60 0.32
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 1.674e-40 0.44
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 4.568e-32 0.41
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5.822e-32 0.44
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 3.929e-29 0.41
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 9.478e-23 0.39
PDE6A_HUMAN PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 2.917e-20 0.29
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 2.109e-15 0.40
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 4.552e-15 0.41
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 1.306e-13 0.41
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.728e-13 0.30
M3K5_HUMAN MAP3K5 Mitogen-activated protein kinase kinase kinase 5 2.576e-10 0.32
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.003e-09 0.36
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 1.695e-09 0.41
BLK_HUMAN BLK Tyrosine-protein kinase Blk 2.083e-07 0.30
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 1.641e-06 0.38

AR42

A5H660_SCHMA HDAC8 Histone deacetylase 8 1.26e-106 0.43
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.975e-97 0.38
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.847e-67 0.55
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.956e-61 0.55
PRIO_SHEEP PRNP Major prion protein 3.037e-55 0.42
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 5.03e-55 0.40
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5.08e-50 0.34
KCNB2_HUMAN KCNB2 Potassium voltage-gated channel subfamily B member 2 5.386e-48 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.258e-45 0.61
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 1.389e-44 0.35
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.666e-44 0.35
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 9.689e-44 0.34
HDAC2_HUMAN HDAC2 Histone deacetylase 2 3.946e-42 0.55
RCOR3_HUMAN RCOR3 REST corepressor 3 2.905e-40 0.32
LPXC_ECOLI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.526e-39 0.42
ACE_MOUSE Ace Angiotensin-converting enzyme 2.654e-39 0.31
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 6.128e-38 0.34
AMPN_PIG ANPEP Aminopeptidase N 6.788e-38 0.41
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 4.865e-37 0.41
C3SLB7_ECOLX glmU Bifunctional protein GlmU 8.944e-35 0.32
USP_DROME usp Protein ultraspiracle 1.073e-34 0.32
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.61e-30 0.44
AMP1_PLAFQ M1 family aminopeptidase 4.122e-29 0.33
ECR_DROME EcR Ecdysone receptor 1.973e-28 0.32
BLAB_BACCE Metallo-beta-lactamase type 2 4.802e-26 0.29
PEPT1_DERPT DERP1 Peptidase 1 5.075e-26 0.35
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.438e-25 0.33
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 2.258e-25 0.31
MMP13_BOVIN MMP13 Collagenase 3 3.396e-25 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 4.252e-24 0.33
UROK_RAT Plau Urokinase-type plasminogen activator 2.847e-23 0.29
MMP3_HUMAN MMP3 Stromelysin-1 5.498e-23 0.38
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 6.771e-23 0.31
E3UJZ5_SPOLI Ecdysone receptor 3.061e-22 0.33
HDAC7_HUMAN HDAC7 Histone deacetylase 7 5.009e-22 0.40
Q8MWR1_SPOFR USP Ultraspiracle protein 2.654e-21 0.33
Q8MWR2_SPOFR EcR Ecdysteroid receptor 2.654e-21 0.33
EPHB_MYCTO Epoxide hydrolase B 6.654e-21 0.33
ECR_BOMMO EcR Ecdysone receptor 2.123e-20 0.33
MMP2_HUMAN MMP2 72 kDa type IV collagenase 4.68e-20 0.44
Q7K6A1_PLAF7 Histone deacetylase 4.748e-20 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.915e-20 0.37
Q6DMN0_TOXGO CPL Cathepsin L 7.421e-20 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 3.333e-19 0.31
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 8.29e-19 0.30
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 8.596e-19 0.30
PSBA_MARPO psbA Photosystem II protein D1 1.197e-18 0.33
HDAC5_HUMAN HDAC5 Histone deacetylase 5 4.334e-18 0.40
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 5.388e-18 0.31
MMP1_HUMAN MMP1 Interstitial collagenase 6.594e-18 0.38
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 6.968e-18 0.38
O70424_RAT Neuropeptide Y-Y2 receptor 9.056e-18 0.28
VM1B1_BOTAS Snake venom metalloproteinase BaP1 9.771e-18 0.28
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.485e-17 0.29
AMPN_HUMAN ANPEP Aminopeptidase N 3.371e-17 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.11e-16 0.37
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.11e-16 0.32
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.11e-16 0.35
AOC3_MOUSE Aoc3 Membrane primary amine oxidase 2.22e-16 0.31
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.22e-16 0.32
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.22e-16 0.33
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.441e-16 0.39
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 7.772e-16 0.44
HDAC9_HUMAN HDAC9 Histone deacetylase 9 1.11e-15 0.40
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.998e-15 0.31
NEP_RABIT MME Neprilysin 4.33e-15 0.31
MYG_HUMAN MB Myoglobin 4.441e-15 0.29
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.996e-15 0.33
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.996e-15 0.33
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 9.881e-15 0.32
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.31e-14 0.32
TRPV4_RAT Trpv4 Transient receptor potential cation channel subfamily V member 4 3.12e-14 0.36
COLA_CLOPE colA Collagenase ColA 3.475e-14 0.30
CATG_HUMAN CTSG Cathepsin G 4.374e-14 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 9.259e-14 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 1.397e-13 0.40
GPR55_HUMAN GPR55 G-protein coupled receptor 55 1.56e-13 0.40
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.766e-13 0.35
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 1.963e-13 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.011e-13 0.37
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 3.084e-13 0.29
FA7_HUMAN F7 Coagulation factor VII 3.23e-13 0.41
UROK_MOUSE Plau Urokinase-type plasminogen activator 3.922e-13 0.29
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 4.441e-13 0.30
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 6.108e-13 0.28
SENP7_HUMAN SENP7 Sentrin-specific protease 7 6.918e-13 0.38
NR1H4_HUMAN NR1H4 Bile acid receptor 7.488e-13 0.42
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 9.82e-13 0.39
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 2.79e-12 0.37
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 3.37e-12 0.37
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 3.644e-12 0.39
KLK2_HUMAN KLK2 Kallikrein-2 3.82e-12 0.30
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 4.12e-12 0.35
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 5.06e-12 0.29
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.878e-12 0.31
UROK_HUMAN PLAU Urokinase-type plasminogen activator 9.581e-12 0.33
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 2.216e-11 0.41
ADRB3_MACMU ADRB3 Beta-3 adrenergic receptor 2.276e-11 0.31
KLK8_HUMAN KLK8 Kallikrein-8 4.757e-11 0.30
TAAR1_RAT Taar1 Trace amine-associated receptor 1 5.107e-11 0.38
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 5.16e-11 0.40
HDAC4_HUMAN HDAC4 Histone deacetylase 4 7.13e-11 0.44
AMPN_MOUSE Anpep Aminopeptidase N 7.306e-11 0.29
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 1.06e-10 0.31
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 1.336e-10 0.28
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.11e-10 0.30
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.748e-10 0.39
ACRO_HUMAN ACR Acrosin 3.318e-10 0.31
KLK4_HUMAN KLK4 Kallikrein-4 3.484e-10 0.30
PANC_MYCTU panC Pantothenate synthetase 3.536e-10 0.31
PSBA_SPIOL psbA Photosystem II protein D1 4.431e-10 0.33
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 5.064e-10 0.37
AOX_TRYBB AOX Alternative oxidase, mitochondrial 7.2e-10 0.31
V1AR_RAT Avpr1a Vasopressin V1a receptor 7.274e-10 0.36
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 7.282e-10 0.41
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 7.487e-10 0.35
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 8.841e-10 0.34
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 8.906e-10 0.39
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 1.195e-09 0.39
NEP_RAT Mme Neprilysin 1.235e-09 0.37
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.259e-09 0.35
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.45e-09 0.32
EST1_RABIT Liver carboxylesterase 1 1.817e-09 0.29
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 2.406e-09 0.29
FFAR2_MOUSE Ffar2 Free fatty acid receptor 2 2.541e-09 0.35
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.547e-09 0.38
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 3.173e-09 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.25e-09 0.31
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.282e-09 0.31
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 3.427e-09 0.32
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 3.925e-09 0.38
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 4.27e-09 0.33
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.511e-09 0.30
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.494e-09 0.32
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 5.995e-09 0.30
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.894e-09 0.40
UREA_CANEN Urease 7.659e-09 0.38
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 7.796e-09 0.33
MMP8_HUMAN MMP8 Neutrophil collagenase 7.92e-09 0.38
CATL1_BOVIN CTSL Cathepsin L1 9.746e-09 0.30
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 9.913e-09 0.29
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 1.261e-08 0.29
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 1.497e-08 0.39
GLR_HUMAN GCGR Glucagon receptor 1.603e-08 0.39
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.612e-08 0.38
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 1.79e-08 0.30
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.871e-08 0.33
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.122e-08 0.39
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.301e-08 0.31
STXA_SHIDY stxA Shiga toxin subunit A 2.422e-08 0.29
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 2.537e-08 0.36
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 2.601e-08 0.33
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.309e-08 0.37
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 3.519e-08 0.31
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.023e-08 0.33
LEF_BACAN lef Lethal factor 4.171e-08 0.38
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 4.772e-08 0.37
MMP13_RAT Mmp13 Collagenase 3 4.778e-08 0.32
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.894e-08 0.39
Q8IL11_PLAF7 M17 leucyl aminopeptidase 6.012e-08 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 6.887e-08 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 7.347e-08 0.31
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 7.661e-08 0.46
CAH2_HUMAN CA2 Carbonic anhydrase 2 7.86e-08 0.39
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 8.595e-08 0.33
V2R_RAT Avpr2 Vasopressin V2 receptor 8.634e-08 0.36
SHH_MOUSE Shh Sonic hedgehog protein 1.236e-07 0.31
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.448e-07 0.39
CTNB1_HUMAN CTNNB1 Catenin beta-1 1.516e-07 0.31
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.75e-07 0.30
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.956e-07 0.36
Q25615_ONCVO Chitinase 2.139e-07 0.31
CTRB_BOVIN Chymotrypsinogen B 2.362e-07 0.29
IL6_HUMAN IL6 Interleukin-6 2.362e-07 0.29
NEP_HUMAN MME Neprilysin 2.677e-07 0.31
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 2.727e-07 0.32
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.216e-07 0.35
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 3.533e-07 0.37
TPA_HUMAN PLAT Tissue-type plasminogen activator 3.662e-07 0.32
SENP1_HUMAN SENP1 Sentrin-specific protease 1 4.466e-07 0.33
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.707e-07 0.30
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 5.06e-07 0.38
Q9ZTP8_MAIZE hd1b Histone deacetylase 5.407e-07 0.33
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.52e-07 0.35
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.565e-07 0.34
CYNT_HELPY cynT Carbonic anhydrase 5.986e-07 0.31
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 6.072e-07 0.31
HSF1_MOUSE Hsf1 Heat shock factor protein 1 7.068e-07 0.33
TRY1_HUMAN PRSS1 Trypsin-1 7.349e-07 0.33
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 7.353e-07 0.31
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.968e-07 0.39
SENP8_HUMAN SENP8 Sentrin-specific protease 8 8.932e-07 0.38
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 9.065e-07 0.33
NOX1_HUMAN NOX1 NADPH oxidase 1 9.106e-07 0.33
SCYD_MAGO7 SDH1 Scytalone dehydratase 9.337e-07 0.30
NK1R_RAT Tacr1 Substance-P receptor 9.688e-07 0.31
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.062e-06 0.35
MMP12_MOUSE Mmp12 Macrophage metalloelastase 1.359e-06 0.29
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.402e-06 0.38
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 1.411e-06 0.39
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.595e-06 0.31
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.611e-06 0.30
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.653e-06 0.35
DEF_PSEAE def Peptide deformylase 1.678e-06 0.29
EST2_HUMAN CES2 Cocaine esterase 2.154e-06 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.568e-06 0.35
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.624e-06 0.39
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.586e-06 0.38
LUCI_AQULA Luciferin 4-monooxygenase 3.933e-06 0.30
AMPL_PIG LAP3 Cytosol aminopeptidase 4.519e-06 0.33
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 4.622e-06 0.41
CAH4_BOVIN CA4 Carbonic anhydrase 4 4.809e-06 0.36
BLA2_BACCE blm Metallo-beta-lactamase type 2 5.327e-06 0.29
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 5.408e-06 0.36
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 5.8e-06 0.31
DNAB_MYCTU dnaB Replicative DNA helicase 6.149e-06 0.40
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 6.194e-06 0.31
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 6.229e-06 0.35
CMA1_HUMAN CMA1 Chymase 6.336e-06 0.32
STRP_STRP1 ska Streptokinase A 6.348e-06 0.38
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 6.358e-06 0.30
CBPA1_BOVIN CPA1 Carboxypeptidase A1 6.516e-06 0.31
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 7.896e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 8.09e-06 0.28
CATB_HUMAN CTSB Cathepsin B 8.265e-06 0.35
CHLE_MOUSE Bche Cholinesterase 8.54e-06 0.29
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 9.308e-06 0.36
MMP7_HUMAN MMP7 Matrilysin 9.715e-06 0.34
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 9.919e-06 0.34

Verdinexor

XPO1_HUMAN XPO1 Exportin-1 1.274e-83 0.44
RXFP2_HUMAN RXFP2 Relaxin receptor 2 6.375e-18 0.28
RXFP1_HUMAN RXFP1 Relaxin receptor 1 3.331e-15 0.32
RHOA_HUMAN RHOA Transforming protein RhoA 1.21e-14 0.31
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 4.525e-11 0.32
ELOV6_MOUSE Elovl6 Elongation of very long chain fatty acids protein 6 9.852e-10 0.28
ELOV3_HUMAN ELOVL3 Elongation of very long chain fatty acids protein 3 4.608e-09 0.28
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 8.719e-09 0.29
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 5.181e-07 0.32
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 6.83e-07 0.29
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.671e-06 0.32
CAN1_RAT Capn1 Calpain-1 catalytic subunit 6.644e-06 0.29
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 7.961e-06 0.37

CC115

LST8_HUMAN MLST8 Target of rapamycin complex subunit LST8 2.136e-83 0.73
RPTOR_HUMAN RPTOR Regulatory-associated protein of mTOR 2.136e-83 0.73
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 4.522e-18 0.34
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 4.448e-07 0.73

Selinexor

XPO1_HUMAN XPO1 Exportin-1 1.913e-73 0.44
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 1.698e-18 0.29

Ruxolitinib (INCB-18424) phosphate

JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.169e-67 0.91
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 7.649e-61 0.91
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.876e-53 0.91
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 3.677e-44 0.91
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 5.13e-43 0.34
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 5.393e-40 0.91
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 3.052e-32 0.91
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 1.832e-27 0.91
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 7.174e-23 0.91
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 7.174e-23 0.91
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 7.174e-23 0.91
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 7.174e-23 0.91
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 9.736e-22 0.91
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 9.681e-21 0.91
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 9.681e-21 0.91
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 9.681e-21 0.91
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 4.875e-20 0.91
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 7.456e-20 0.91
DMPK_HUMAN DMPK Myotonin-protein kinase 1.588e-19 0.91
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 1.353e-18 0.91
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 2.417e-18 0.91
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 2.417e-18 0.91
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 9.017e-18 0.91
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 1.08e-17 0.91
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.08e-17 0.91
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 4.901e-17 0.91
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 4.901e-17 0.91
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 2.22e-16 0.91
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 1.332e-15 0.91
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 1.332e-15 0.91
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 3.664e-15 0.91
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 4.552e-15 0.91
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 9.215e-15 0.91
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 9.215e-15 0.91
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 9.215e-15 0.91
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 2.187e-14 0.91
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 2.187e-14 0.91
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 4.896e-14 0.91
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 4.896e-14 0.91
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 7.15e-14 0.34
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 1.042e-13 0.91
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 2.125e-13 0.91
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.125e-13 0.91
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 2.125e-13 0.91
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 2.146e-13 0.91
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 4.159e-13 0.91
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 4.159e-13 0.91
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 9.724e-13 0.34
SYT_YERPE thrS Threonine--tRNA ligase 9.724e-13 0.34
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 1.43e-12 0.91
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 1.43e-12 0.91
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 2.527e-12 0.91
DAPK1_HUMAN DAPK1 Death-associated protein kinase 1 4.342e-12 0.91
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 7.266e-12 0.91
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 7.266e-12 0.91
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 7.266e-12 0.91
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.29e-11 0.34
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 4.548e-11 0.91
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.015e-10 0.91
TPX2_HUMAN TPX2 Targeting protein for Xklp2 1.396e-10 0.31
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 3.015e-10 0.91
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.015e-10 0.91
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 3.434e-10 0.91
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 3.434e-10 0.91
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.905e-09 0.91
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 3.206e-09 0.91
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.252e-09 0.91
GRK5_HUMAN GRK5 G protein-coupled receptor kinase 5 7.097e-09 0.91
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 1.397e-08 0.91
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 1.661e-08 0.91
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 3.404e-08 0.91
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 5.797e-08 0.91
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 5.748e-07 0.91
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 9.274e-07 0.91
GAK_HUMAN GAK Cyclin-G-associated kinase 1.297e-06 0.91
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.297e-06 0.91
AURKC_HUMAN AURKC Aurora kinase C 1.444e-06 0.91
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 6.402e-06 0.91
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 8.128e-06 0.91

Itacitinib

JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 2.008e-61 0.55
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.263e-50 0.55
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 9.107e-41 0.32
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 2.187e-26 0.55
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 4.499e-23 0.55
TAB1_HUMAN TAB1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 3.077e-20 0.31
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 4.666e-18 0.40
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 7.772e-16 0.34
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 9.437e-15 0.40
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 1.232e-14 0.40
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 3.563e-13 0.32
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 1.593e-12 0.40
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 6.898e-12 0.40
DMPK_HUMAN DMPK Myotonin-protein kinase 1.37e-11 0.40
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 4.767e-11 0.40
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 4.879e-11 0.32
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 1.437e-10 0.40
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 1.715e-10 0.40
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 1.715e-10 0.40
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 1.715e-10 0.40
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.715e-10 0.40
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 3.851e-10 0.40
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 3.851e-10 0.40
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 4.435e-10 0.34
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 5.445e-10 0.40
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 9.346e-10 0.40
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 1.507e-09 0.40
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 1.507e-09 0.40
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 1.507e-09 0.40
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 3.726e-09 0.40
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.744e-08 0.40
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.744e-08 0.40
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 3.392e-08 0.40
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.392e-08 0.40
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.918e-07 0.40
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 2.918e-07 0.40
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 3.425e-07 0.40
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 4.535e-07 0.40
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 6.837e-07 0.40
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 6.837e-07 0.40
RIOK3_HUMAN RIOK3 Serine/threonine-protein kinase RIO3 6.837e-07 0.40
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 1.003e-06 0.40
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 1.003e-06 0.40
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 1.437e-06 0.40
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 1.437e-06 0.40
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 2.015e-06 0.40
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 2.768e-06 0.40
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.768e-06 0.40
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 2.768e-06 0.40
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 3.736e-06 0.40
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 3.736e-06 0.40
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 3.778e-06 0.30
SYT_YERPE thrS Threonine--tRNA ligase 3.778e-06 0.30
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 3.844e-06 0.40
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 3.844e-06 0.40
DAPK2_HUMAN DAPK2 Death-associated protein kinase 2 6.488e-06 0.40
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 6.488e-06 0.40
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 8.371e-06 0.40

SAR20347

KPYR_HUMAN PKLR Pyruvate kinase PKLR 6.752e-50 0.35
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 8.754e-44 0.36
AURKB_MOUSE Aurkb Aurora kinase B 1.574e-41 0.33
BTK_MOUSE Btk Tyrosine-protein kinase BTK 2.201e-33 0.36
AURKA_MOUSE Aurka Aurora kinase A 5.459e-28 0.33
BTK_HUMAN BTK Tyrosine-protein kinase BTK 7.571e-20 0.41
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 5.427e-19 0.44
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.11e-16 0.32
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.11e-16 0.33
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 8.882e-16 0.29
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 8.882e-15 0.33
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 8.882e-15 0.33
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 1.509e-13 0.33
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.122e-12 0.31
SC6A9_MOUSE Slc6a9 Sodium- and chloride-dependent glycine transporter 1 2.708e-11 0.30
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 3.477e-11 0.41
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.324e-10 0.43
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 3.308e-10 0.44
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 4.539e-10 0.44
PE2R3_RAT Ptger3 Prostaglandin E2 receptor EP3 subtype 6.69e-10 0.29
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 9.852e-10 0.28
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 1.651e-09 0.37
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.647e-09 0.34
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 2.969e-09 0.41
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 4.1e-09 0.40
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 6.013e-09 0.38
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 6.487e-09 0.36
TEC_HUMAN TEC Tyrosine-protein kinase Tec 8.619e-09 0.36
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.5e-08 0.36
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.778e-08 0.35
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 6.699e-08 0.33
REV1_HUMAN REV1 DNA repair protein REV1 9.328e-08 0.29
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 1.487e-07 0.31
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 1.58e-07 0.33
ACK1_MOUSE Tnk2 Activated CDC42 kinase 1 2.608e-07 0.30
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 3.685e-07 0.36
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 4.382e-07 0.33
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 7.979e-07 0.33
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 8.895e-07 0.33
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.014e-06 0.36
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 1.106e-06 0.28
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.139e-06 0.33
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.846e-06 0.32
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 1.871e-06 0.41
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.263e-06 0.30
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 5.636e-06 0.30
T23O_HUMAN TDO2 Tryptophan 2,3-dioxygenase 5.979e-06 0.33
ALK_HUMAN ALK ALK tyrosine kinase receptor 6.657e-06 0.37
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 8.74e-06 0.32

Eltrombopag Olamine

TPOR_HUMAN MPL Thrombopoietin receptor 1.536e-41 0.51
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 5.329e-15 0.32

Bithionol

ERMC1_STAAU ermC rRNA adenine N-6-methyltransferase 7.142e-37 0.29
G3V906_RAT Hcar1 Hydroxycarboxylic acid receptor 1 1.377e-35 0.28
ACLY_HUMAN ACLY ATP-citrate synthase 1.056e-19 0.36
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.523e-18 0.29
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 4.628e-12 0.29
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 6.962e-11 0.39
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 6.44e-08 0.29
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.949e-07 0.45
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 3.205e-07 0.29
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.485e-06 0.42
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 4.731e-06 0.42
COMT_RAT Comt Catechol O-methyltransferase 6.253e-06 0.29

Tasisulam

SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 5.184e-26 0.37
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 1.839e-23 0.29
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 3.22e-15 0.39
F16P1_MOUSE Fbp1 Fructose-1,6-bisphosphatase 1 7.55e-15 0.35
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 2.065e-14 0.31
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 1.463e-13 0.33
F264_HUMAN PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 8.011e-12 0.30
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.146e-11 0.38
Q6DMN0_TOXGO CPL Cathepsin L 2.335e-11 0.33
SC6A9_MOUSE Slc6a9 Sodium- and chloride-dependent glycine transporter 1 3.176e-11 0.30
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 5.778e-11 0.28
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 5.778e-11 0.28
H9CNL0_SPOEX Ryanodien receptor 1.577e-10 0.28
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 2.582e-10 0.38
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 1.923e-09 0.33
FEN1_HUMAN FEN1 Flap endonuclease 1 5.971e-09 0.38
METC_ECOLI metC Cystathionine beta-lyase MetC 8.709e-09 0.35
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.986e-08 0.38
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 3.789e-08 0.31
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 5.984e-08 0.33
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 7.82e-08 0.33
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.251e-07 0.37
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 2.532e-07 0.33
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 2.879e-07 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 3.463e-07 0.40
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 3.96e-07 0.30
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 4.905e-07 0.29
CCR4_MOUSE Ccr4 C-C chemokine receptor type 4 5.972e-07 0.30
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 6.257e-07 0.29
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 7.838e-07 0.30
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 9.396e-07 0.29
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 9.642e-07 0.29
A3KMY8_BOVIN GUSB Beta-glucuronidase 1.244e-06 0.28
POLG_HCV1 Genome polyprotein 1.516e-06 0.32
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 3.617e-06 0.30
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 3.933e-06 0.30
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 8.499e-06 0.35

TAK-659 hydrochloride

KSYK_HUMAN SYK Tyrosine-protein kinase SYK 5.92e-18 0.98
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 2.253e-17 0.98
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.626e-12 0.98
PB2_I34A1 PB2 Polymerase basic protein 2 1.358e-09 0.33
FER_HUMAN FER Tyrosine-protein kinase Fer 8.31e-08 0.98
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 1.832e-07 0.37
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 6.183e-07 0.98
SYK_HUMAN KARS1 Lysine--tRNA ligase 6.556e-07 0.29

Alexidine dihydrochloride

NOS2_RAT Nos2 Nitric oxide synthase, inducible 5.338e-13 0.28
DHYS_RAT Dhps Deoxyhypusine synthase 6.519e-08 0.33