Results of Job: search_7415eba6-e0b2-4b03-857f-a1ec07ab31fa

Query Target Key Target Name Description P-Value MaxTC

Hexamidine

ACRO_PIG ACR Acrosin 2.389e-247 1.00
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 2.9e-124 1.00
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 1.872e-57 1.00
TRY1_HUMAN PRSS1 Trypsin-1 1.473e-43 1.00
S100B_HUMAN S100B Protein S100-B 1.735e-32 1.00
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.937e-30 1.00
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 3.693e-26 1.00
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 6.746e-21 1.00
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.197e-20 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 7.339e-20 1.00
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.207e-06 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.882e-05 1.00
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 0.001681 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.003008 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.0173 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.03486 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.03766 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.04984 1.00
STRP_STRP1 ska Streptokinase A 0.1079 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.3005 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.3287 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.6581 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.6956 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.7051 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.8581 1.00
KLK_PIG Glandular kallikrein 5.215e-163 0.56
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 8.108e-115 0.44
S100B_RAT S100b Protein S100-B 5.939e-100 0.53
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.921e-82 0.48
FA10_BOVIN F10 Coagulation factor X 3.18e-75 0.62
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.935e-65 0.50
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.62e-49 0.56
THRB_BOVIN F2 Prothrombin 2.87e-41 0.62
TRY1_BOVIN Cationic trypsin 9.424e-41 0.56
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 2.317e-40 0.32
O69638_MYCTO Hydrolase, alpha/beta hydrolase fold family 5.351e-37 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 5.633e-36 0.40
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 8.011e-33 0.35
ENTK_HUMAN TMPRSS15 Enteropeptidase 3.111e-32 0.36
PLMN_HUMAN PLG Plasminogen 4.771e-29 0.56
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 8.234e-29 0.35
LSS_HUMAN LSS Lanosterol synthase 1.122e-28 0.39
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 3.198e-28 0.39
THRB_HUMAN F2 Prothrombin 1.005e-25 0.58
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.433e-25 0.34
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 2.44e-21 0.45
ACRO_HUMAN ACR Acrosin 3.128e-20 0.42
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.228e-19 0.36
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 2.805e-19 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.903e-19 0.40
PAR16_HUMAN PARP16 Protein mono-ADP-ribosyltransferase PARP16 1.594e-18 0.35
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 3.743e-18 0.43
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.47e-17 0.62
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.544e-17 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.007e-17 0.35
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 4.583e-17 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.11e-16 0.36
HRH3_CAVPO HRH3 Histamine H3 receptor 1.11e-16 0.36
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 2.22e-16 0.34
ITB3_HUMAN ITGB3 Integrin beta-3 6.661e-16 0.45
KLK1_HUMAN KLK1 Kallikrein-1 8.771e-15 0.48
FA10_HUMAN F10 Coagulation factor X 4.641e-14 0.50
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 9.504e-14 0.30
HRH3_HUMAN HRH3 Histamine H3 receptor 1.102e-13 0.36
SQHC_ALIAD shc Squalene--hopene cyclase 2.506e-13 0.38
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 7.311e-13 0.28
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 1.02e-12 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 1.228e-12 0.37
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.893e-12 0.48
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.935e-12 0.35
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.525e-12 0.41
HRH1_HUMAN HRH1 Histamine H1 receptor 1.299e-11 0.34
HRH2_HUMAN HRH2 Histamine H2 receptor 1.866e-11 0.33
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 8.505e-11 0.37
KLK8_HUMAN KLK8 Kallikrein-8 1.369e-10 0.28
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.758e-10 0.45
ESR1_HUMAN ESR1 Estrogen receptor 2.103e-10 0.39
CHLE_HORSE BCHE Cholinesterase 2.32e-10 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.525e-10 0.35
PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 3.352e-10 0.35
KLK4_HUMAN KLK4 Kallikrein-4 9.181e-10 0.28
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.208e-09 0.40
AHR_RABIT AHR Aryl hydrocarbon receptor 1.628e-09 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 6.429e-09 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.371e-08 0.35
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 1.751e-08 0.34
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 1.922e-08 0.33
RARB_HUMAN RARB Retinoic acid receptor beta 2.21e-08 0.46
CBPB1_PIG CPB1 Carboxypeptidase B 2.824e-08 0.34
HRH3_MOUSE Hrh3 Histamine H3 receptor 3.231e-08 0.30
STS_HUMAN STS Steryl-sulfatase 3.869e-08 0.35
FA7_HUMAN F7 Coagulation factor VII 5.098e-08 0.34
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 6.136e-08 0.34
THA_HUMAN THRA Thyroid hormone receptor alpha 6.938e-08 0.40
ACES_ELEEL ache Acetylcholinesterase 8.192e-08 0.36
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.342e-07 0.30
A4_HUMAN APP Amyloid-beta precursor protein 1.591e-07 0.33
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.619e-07 0.36
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 2.014e-07 0.30
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 2.06e-07 0.36
LYAG_MOUSE Gaa Lysosomal alpha-glucosidase 2.362e-07 0.29
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 2.651e-07 0.30
CP19A_HUMAN CYP19A1 Aromatase 3.506e-07 0.39
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 3.662e-07 0.29
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 8.351e-07 0.37
AOC1_RAT Aoc1 Amiloride-sensitive amine oxidase [copper-containing] 9.396e-07 0.29
HMOX2_RAT Hmox2 Heme oxygenase 2 1.225e-06 0.33
LSS_RAT Lss Lanosterol synthase 1.479e-06 0.32
HEPS_HUMAN HPN Serine protease hepsin 1.584e-06 0.33
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.594e-06 0.38
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.886e-06 0.32
TRYP_PIG Trypsin 3.189e-06 0.33
AGP1_YEAST AGP1 General amino acid permease AGP1 4.296e-06 0.30
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 7.575e-06 0.36
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.707e-06 0.30
O61059_LEIME LmGT2 Glucose transporter 8.107e-06 0.49
LYOX_HUMAN LOX Protein-lysine 6-oxidase 8.755e-06 0.28
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 9.847e-06 0.29

Roxadustat

EGLN1_HUMAN EGLN1 Egl nine homolog 1 6.456e-164 1.00
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.025e-59 1.00
EGLN2_HUMAN EGLN2 Egl nine homolog 2 2.696e-214 0.60
EGLN1_RAT Egln1 Egl nine homolog 1 1.84e-108 0.38
BODG_PSESK Gamma-butyrobetaine dioxygenase 1.263e-84 0.54
CRTM_STAAU crtM 4,4'-diapophytoene synthase 9.598e-56 0.34
MCL1_MOUSE Mcl1 Induced myeloid leukemia cell differentiation protein Mcl-1 homolog 6.008e-49 0.34
Q25615_ONCVO Chitinase 1.843e-39 0.34
NAC1_HUMAN SLC8A1 Sodium/calcium exchanger 1 5.401e-39 0.34
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.003e-37 0.33
KAT1_HUMAN KYAT1 Kynurenine--oxoglutarate transaminase 1 3.875e-36 0.29
THA_HUMAN THRA Thyroid hormone receptor alpha 5.672e-34 0.38
THB_RAT Thrb Thyroid hormone receptor beta 3.408e-33 0.34
THB_HUMAN THRB Thyroid hormone receptor beta 1.349e-32 0.38
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.165e-31 0.33
EGLN3_HUMAN EGLN3 Egl nine homolog 3 2.607e-31 0.40
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 1.435e-30 0.34
PA_I34A1 PA Polymerase acidic protein 7.388e-24 0.33
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 2.171e-19 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.228e-18 0.37
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 3.371e-18 0.39
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 4.879e-18 0.29
FDFT_HUMAN FDFT1 Squalene synthase 6.916e-18 0.34
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 9.235e-18 0.29
PANC_MYCTU panC Pantothenate synthetase 4.115e-17 0.37
AMP1_PLAFQ M1 family aminopeptidase 1.11e-16 0.32
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 1.11e-16 0.31
CGAS_HUMAN CGAS Cyclic GMP-AMP synthase 2.22e-16 0.31
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 3.22e-15 0.31
ANDR_MOUSE Ar Androgen receptor 5.773e-15 0.32
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 7.883e-15 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 9.215e-15 0.35
ELNE_MOUSE Elane Neutrophil elastase 9.504e-14 0.34
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 6.568e-13 0.32
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 8.195e-13 0.37
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.42e-12 0.35
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 3.176e-12 0.32
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 3.63e-12 0.30
CD69_HUMAN CD69 Early activation antigen CD69 1.508e-11 0.28
O39930_9HEPC NS5b RNA-directed RNA polymerase 1.521e-11 0.35
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 1.628e-11 0.33
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 2.19e-11 0.33
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 4.393e-11 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 4.627e-11 0.33
MMP13_HUMAN MMP13 Collagenase 3 4.797e-11 0.33
HXK4_HUMAN GCK Hexokinase-4 1.05e-10 0.39
ITF2_HUMAN TCF4 Transcription factor 4 1.309e-10 0.28
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.317e-10 0.30
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 4.007e-10 0.35
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 6.016e-10 0.35
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 6.353e-10 0.35
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 8.177e-10 0.32
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 8.387e-10 0.32
NR1H2_MOUSE Nr1h2 Oxysterols receptor LXR-beta 1.012e-09 0.28
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 2.012e-09 0.31
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 4.331e-09 0.31
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 4.61e-09 0.35
MGLL_HUMAN MGLL Monoglyceride lipase 5.875e-09 0.32
NEP_RAT Mme Neprilysin 9.926e-09 0.35
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.198e-08 0.36
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.352e-08 0.34
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.586e-08 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.813e-08 0.28
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 2.474e-08 0.35
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 2.799e-08 0.33
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.868e-08 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 3.314e-08 0.32
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 3.342e-08 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.711e-08 0.31
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.924e-08 0.32
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.218e-07 0.34
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 2.436e-07 0.32
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 2.44e-07 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 4.065e-07 0.30
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 7.144e-07 0.33
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 7.167e-07 0.32
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 7.434e-07 0.36
DYR_BOVIN DHFR Dihydrofolate reductase 8.094e-07 0.32
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 1.019e-06 0.28
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 1.142e-06 0.28
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 1.338e-06 0.30
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.517e-06 0.35
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.795e-06 0.37
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.045e-06 0.31
FEN1_HUMAN FEN1 Flap endonuclease 1 2.19e-06 0.34
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 2.395e-06 0.31
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.546e-06 0.37
PRIO_SHEEP PRNP Major prion protein 2.849e-06 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 3.38e-06 0.31
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 3.616e-06 0.30
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.976e-06 0.31
PRTN3_HUMAN PRTN3 Myeloblastin 4.347e-06 0.34
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 4.397e-06 0.36
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.924e-06 0.37
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 6.323e-06 0.30
P2RX3_HUMAN P2RX3 P2X purinoceptor 3 6.677e-06 0.43
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 6.753e-06 0.34
LYOX_HUMAN LOX Protein-lysine 6-oxidase 7.112e-06 0.29
BAD_HUMAN BAD Bcl2-associated agonist of cell death 7.578e-06 0.37
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 8.683e-06 0.29

Clevidipine

CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.2e-161 1.00
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 7.982e-114 0.46
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 4.289e-91 0.46
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 6.884e-50 0.35
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.16e-49 0.52
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 4.721e-47 0.45
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.124e-44 0.36
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 4.314e-36 0.52
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 2.487e-34 0.45
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.986e-32 0.53
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.861e-31 0.52
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 2.304e-30 0.37
Q03732_HBV HBcAg Capsid protein 1.141e-27 0.33
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 2.4e-27 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.05e-24 0.34
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 3.5e-23 0.45
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 6.661e-16 0.52
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 2.974e-12 0.35
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 1.787e-10 0.41
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.488e-09 0.36
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 4.078e-09 0.29
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 7.857e-09 0.34
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.842e-06 0.35
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.959e-06 0.52

Maraviroc

CCR5_MACMU CCR5 C-C chemokine receptor type 5 2.503e-151 1.00
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 2.631e-91 1.00
CCR5_MOUSE Ccr5 C-C chemokine receptor type 5 2.698e-09 1.00
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 4.614e-68 0.31
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 2.039e-33 0.31
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 2.084e-27 0.30
Q8WSF8_APLCA Soluble acetylcholine receptor 2.223e-17 0.29
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 4.236e-12 0.29
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.158e-11 0.33
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 8.293e-09 0.32
RENI_MACFA REN Renin 1.212e-08 0.32
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.396e-08 0.30
ACHP_LYMST Acetylcholine-binding protein 1.127e-07 0.29
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.282e-07 0.33
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 3.729e-07 0.31
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 5.012e-07 0.31
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 5.012e-07 0.31
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 5.012e-07 0.31
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 5.012e-07 0.31
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 5.012e-07 0.31
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 5.012e-07 0.31
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 5.012e-07 0.31
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 5.012e-07 0.31
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 5.012e-07 0.31
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 5.012e-07 0.31
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 5.012e-07 0.31
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 5.012e-07 0.31
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 5.012e-07 0.31
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 5.012e-07 0.31
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 5.012e-07 0.31
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 5.012e-07 0.31
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 5.012e-07 0.31
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 5.012e-07 0.31
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 1.155e-06 0.31
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 2.028e-06 0.29
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.216e-06 0.29
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 5.732e-06 0.72

Nilotinib

BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 4.085e-149 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.085e-77 1.00
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.139e-74 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.969e-73 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 6.143e-65 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.215e-57 1.00
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.625e-55 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 4.359e-50 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.919e-48 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 4.316e-45 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.942e-32 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 5.303e-31 1.00
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 2.175e-29 1.00
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 2.505e-28 1.00
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.144e-27 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 5.308e-26 1.00
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.565e-25 1.00
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 7.773e-24 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.051e-23 1.00
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.696e-21 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.001e-19 1.00
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.075e-18 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.21e-18 1.00
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 6.398e-18 1.00
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 1.11e-16 1.00
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.22e-16 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 3.331e-16 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 5.551e-16 1.00
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.432e-14 1.00
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 6.084e-14 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.351e-13 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 2.184e-13 1.00
CAH3_HUMAN CA3 Carbonic anhydrase 3 7.175e-13 1.00
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 7.175e-13 1.00
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 9.469e-13 1.00
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.584e-12 1.00
CAH13_MOUSE Ca13 Carbonic anhydrase 13 5.862e-12 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 9.352e-12 1.00
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 1.001e-11 1.00
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.203e-11 1.00
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 2.718e-11 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.307e-11 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 6.599e-11 1.00
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 7.48e-11 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.818e-10 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 1.839e-10 1.00
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.977e-10 1.00
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 5.058e-10 1.00
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.555e-09 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 5.842e-07 1.00
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 6.44e-07 1.00
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 2.404e-06 1.00
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 2.583e-06 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.03e-06 1.00
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 7.605e-06 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.101e-05 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 0.0001466 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 0.0003202 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 0.0006726 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 0.0008312 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 0.0009832 1.00
CAH4_HUMAN CA4 Carbonic anhydrase 4 0.001375 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 0.002251 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 0.007532 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 0.585 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 0.7794 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.8351 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 0.961 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.9944 1.00
BCR_HUMAN BCR Breakpoint cluster region protein 3.029e-88 0.50
INSR_HUMAN INSR Insulin receptor 3.785e-57 0.55
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 1.201e-56 0.43
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 4.386e-55 0.52
GSK3B_RAT Gsk3b Glycogen synthase kinase-3 beta 8.873e-46 0.37
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 2.084e-45 0.52
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 1.119e-39 0.52
SHH_MOUSE Shh Sonic hedgehog protein 4.709e-39 0.40
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 7.115e-38 0.36
RXFP1_HUMAN RXFP1 Relaxin receptor 1 9.31e-38 0.37
GYRB_STRPN gyrB DNA gyrase subunit B 6.46e-37 0.34
Q7X1P7_STREE parE DNA topoisomerase (ATP-hydrolyzing) 6.46e-37 0.34
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 9.966e-30 0.38
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 1.127e-29 0.35
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 3.214e-28 0.39
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 4.339e-28 0.52
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.835e-27 0.61
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 3.941e-27 0.33
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 1.083e-26 0.35
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 7.052e-26 0.35
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 6.092e-25 0.34
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 6.931e-23 0.31
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 4.343e-22 0.36
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.219e-21 0.30
FGFR3_MOUSE Fgfr3 Fibroblast growth factor receptor 3 8.931e-21 0.40
FGFR4_MOUSE Fgfr4 Fibroblast growth factor receptor 4 8.931e-21 0.40
FGR_MOUSE Fgr Tyrosine-protein kinase Fgr 8.931e-21 0.40
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 2.585e-19 0.52
KLK14_HUMAN KLK14 Kallikrein-14 9.376e-19 0.30
SYK_HUMAN KARS1 Lysine--tRNA ligase 4.134e-18 0.33
BMX_MOUSE Bmx Cytoplasmic tyrosine-protein kinase BMX 4.666e-18 0.40
EPHB2_MOUSE Ephb2 Ephrin type-B receptor 2 4.666e-18 0.40
LYN_MOUSE Lyn Tyrosine-protein kinase Lyn 4.666e-18 0.40
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.413e-18 0.52
RXFP2_HUMAN RXFP2 Relaxin receptor 2 7.502e-18 0.28
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 5.445e-17 0.35
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 1.11e-16 0.29
ALK_MOUSE Alk ALK tyrosine kinase receptor 4.441e-16 0.40
EPHA3_MOUSE Epha3 Ephrin type-A receptor 3 4.441e-16 0.40
MK09_MOUSE Mapk9 Mitogen-activated protein kinase 9 4.441e-16 0.40
RET_MOUSE Ret Proto-oncogene tyrosine-protein kinase receptor Ret 4.441e-16 0.40
ROS1_MOUSE Ros1 Proto-oncogene tyrosine-protein kinase ROS 4.441e-16 0.40
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.441e-16 0.52
TIE1_MOUSE Tie1 Tyrosine-protein kinase receptor Tie-1 4.441e-16 0.40
JUN_HUMAN JUN Transcription factor AP-1 1.887e-15 0.33
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 3.331e-15 0.40
Q76129_9HIV1 gag Structural capsid protein 3.553e-15 0.34
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 7.216e-15 0.34
INHBA_MOUSE Inhba Inhibin beta A chain 7.216e-15 0.28
FLT3_MOUSE Flt3 Receptor-type tyrosine-protein kinase FLT3 1.232e-14 0.40
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 1.898e-14 0.52
TXK_HUMAN TXK Tyrosine-protein kinase TXK 3.297e-14 0.36
CDKL1_HUMAN CDKL1 Cyclin-dependent kinase-like 1 1.602e-13 0.29
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 1.801e-13 0.40
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 3.217e-13 0.38
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 3.949e-13 0.35
BTK_HUMAN BTK Tyrosine-protein kinase BTK 4.904e-13 0.40
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 4.974e-13 0.38
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.13e-12 0.32
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 1.734e-12 0.31
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 2.471e-12 0.31
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 2.471e-12 0.31
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.096e-11 0.38
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1.224e-11 0.35
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 2.224e-11 0.38
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 2.224e-11 0.38
NICA_HUMAN NCSTN Nicastrin 2.224e-11 0.38
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 2.248e-11 0.38
PSN2_HUMAN PSEN2 Presenilin-2 2.321e-11 0.38
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 3.777e-11 0.35
PSN1_HUMAN PSEN1 Presenilin-1 6.236e-11 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 8.189e-11 0.49
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.371e-10 0.38
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.642e-10 0.29
INSR_MOUSE Insr Insulin receptor 1.715e-10 0.40
O96526_LEIMA CRK3 Cdc2-related kinase 1.731e-10 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 4.7e-10 0.38
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 4.982e-10 0.39
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 1.183e-09 0.38
TEC_HUMAN TEC Tyrosine-protein kinase Tec 5.458e-09 0.36
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 7.35e-09 0.36
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 8.668e-09 0.52
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 1.015e-08 0.35
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.08e-08 0.37
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.277e-08 0.52
PANK1_HUMAN PANK1 Pantothenate kinase 1 4.728e-08 0.28
AURKA_HUMAN AURKA Aurora kinase A 5.22e-08 0.39
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 5.89e-08 0.52
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 8.839e-08 0.29
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 9.481e-08 0.32
KPCA_HUMAN PRKCA Protein kinase C alpha type 1.5e-07 0.47
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 1.555e-07 0.32
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.696e-07 0.32
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.848e-07 0.33
TPOR_HUMAN MPL Thrombopoietin receptor 2.386e-07 0.31
PANK3_HUMAN PANK3 Pantothenate kinase 3 2.753e-07 0.28
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 2.96e-07 0.38
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 4.566e-07 0.29
HSF1_HUMAN HSF1 Heat shock factor protein 1 5.957e-07 0.31
MTAP2_HUMAN MAP2 Microtubule-associated protein 2 7.357e-07 0.29
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 7.624e-07 0.32
PRIO_SHEEP PRNP Major prion protein 7.856e-07 0.31
HDAC4_HUMAN HDAC4 Histone deacetylase 4 9.143e-07 0.35
HDAC6_HUMAN HDAC6 Histone deacetylase 6 9.859e-07 0.44
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 1.52e-06 0.38
KLK5_HUMAN KLK5 Kallikrein-5 1.676e-06 0.30
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 2.118e-06 0.34
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 2.492e-06 0.34
AURKB_HUMAN AURKB Aurora kinase B 2.797e-06 0.38
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 3.041e-06 0.34
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 3.536e-06 0.33
FAK1_HUMAN PTK2 Focal adhesion kinase 1 3.564e-06 0.33
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 6.671e-06 0.31
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 6.91e-06 0.29
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 7.191e-06 0.31
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 7.196e-06 0.36
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 8.371e-06 0.40
GYRB_STAAU gyrB DNA gyrase subunit B 9.318e-06 0.30

Thymidine

KITH_HUMAN TK1 Thymidine kinase, cytosolic 6.456e-143 1.00
A3RLP8_CHV1 UL23 Thymidine kinase 1.564e-136 1.00
KITH_HHV1S TK Thymidine kinase 9.361e-101 1.00
Q03732_HBV HBcAg Capsid protein 1.377e-17 1.00
KTHY_MYCTU tmk Thymidylate kinase 3.812e-138 0.74
TYSY_LACCA thyA Thymidylate synthase 1.375e-123 0.70
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 4.512e-120 0.65
TYPH_RAT Tymp Thymidine phosphorylase 3.644e-117 0.51
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 1.78e-115 0.53
CDD_HUMAN CDA Cytidine deaminase 5.324e-104 0.34
DNK_DROME dnk Deoxynucleoside kinase 1.043e-102 0.59
KITH_RAT Tk1 Thymidine kinase, cytosolic 1.979e-99 0.79
KITH_VZVD TK Thymidine kinase 6.017e-98 0.42
D3ZGQ2_RAT Tk2 Thymidine kinase 2 3.871e-83 0.67
KTHY_HUMAN DTYMK Thymidylate kinase 8.379e-75 0.45
TYSY_BOVIN TYMS Thymidylate synthase 3.442e-71 0.46
CDD_MOUSE Cda Cytidine deaminase 1.777e-69 0.35
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.862e-69 0.47
TYSY_MYCTU thyA Thymidylate synthase ThyA 4.557e-66 0.53
DPOD1_HUMAN POLD1 DNA polymerase delta catalytic subunit 1.447e-64 0.52
Q6L709_HHV2 TK Thymidine kinase 1.896e-61 0.53
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 7.654e-53 0.53
KITH_HHV1 TK Thymidine kinase 2.043e-39 0.60
NT5M_HUMAN NT5M 5'(3')-deoxyribonucleotidase, mitochondrial 4.536e-38 0.30
DPOLB_HUMAN POLB DNA polymerase beta 4.861e-37 0.61
GGTA1_BOVIN GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 6.395e-36 0.28
Q8KHJ3_NEIME lgtC Alpha 1,4 galactosyltransferase 6.395e-36 0.28
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.992e-33 0.46
DPOL_HHV1K DNA polymerase catalytic subunit 6.67e-32 0.52
KITH_VZVO TK Thymidine kinase 9.257e-32 0.39
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 2.03e-30 0.40
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 4.714e-28 0.46
P2RY6_RAT P2ry6 P2Y purinoceptor 6 2.645e-27 0.33
TYSY_MOUSE Tyms Thymidylate synthase 1.554e-26 0.74
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 4.502e-26 0.32
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 4.502e-26 0.32
ADA_MOUSE Ada Adenosine deaminase 4.212e-24 0.30
TYPH_HUMAN TYMP Thymidine phosphorylase 1.512e-23 0.57
DPOL_HHV11 DNA polymerase catalytic subunit 4.622e-23 0.52
DPOL_VZVD DNA polymerase catalytic subunit 4.622e-23 0.52
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 8.715e-21 0.53
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 6.068e-20 0.79
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 3.774e-17 0.33
ADA_BOVIN ADA Adenosine deaminase 1.11e-15 0.46
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 1.554e-15 0.71
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 1.776e-15 0.46
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 4.108e-15 0.71
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 4.441e-15 0.37
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 5.44e-15 0.28
TYSY_HUMAN TYMS Thymidylate synthase 2.709e-14 0.56
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.277e-13 0.38
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 9.009e-13 0.64
CHLE_HUMAN BCHE Cholinesterase 4.089e-12 0.50
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.101e-11 0.33
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 3.772e-11 0.33
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.137e-10 0.32
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.399e-09 0.45
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 1.495e-08 0.33
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 5.567e-06 0.28

Ceftobiprole

Q7DHH4_STAAU mecA MecA 2.9e-124 1.00
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 2.136e-30 0.35
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 3.736e-23 0.28
B2ZTR6_ACIBA Beta-lactamase 4.398e-22 0.35
D6NSM8_ACIBA ampC Beta-lactamase 4.398e-22 0.35
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.312e-19 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 6.715e-19 0.35
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 3.22e-15 0.29
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 7.425e-11 0.44
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.453e-08 0.28
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.053e-07 0.35

D-Serine

AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 2.9e-124 1.00
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 0.0003763 1.00
GLN1B_ECOLI glnA Glutamine synthetase 3.806e-87 0.44
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 6.328e-87 0.38
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 2.24e-80 0.48
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 2.319e-77 0.38
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 2.392e-77 0.48
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.133e-71 0.42
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 1.915e-65 0.44
GSH1_HUMAN GCLC Glutamate--cysteine ligase catalytic subunit 1.209e-61 0.34
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 2.134e-58 0.44
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 2.231e-58 0.33
KYNU_HUMAN KYNU Kynureninase 4.654e-57 0.34
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 1.638e-55 0.48
DHAS_HELPY asd Aspartate-semialdehyde dehydrogenase 3.573e-55 0.44
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 3.573e-55 0.44
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 5.22e-55 0.48
ARGI1_HUMAN ARG1 Arginase-1 6.267e-54 0.38
ARGI2_HUMAN ARG2 Arginase-2, mitochondrial 1.098e-47 0.38
GRIA1_HUMAN GRIA1 Glutamate receptor 1 1.981e-46 0.38
BHMT2_HUMAN BHMT2 S-methylmethionine--homocysteine S-methyltransferase BHMT2 3.987e-46 0.37
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 2.038e-45 0.41
GRIA2_RAT Gria2 Glutamate receptor 2 7.244e-42 0.36
OTC_HUMAN OTC Ornithine carbamoyltransferase, mitochondrial 8.37e-41 0.32
TY3H_RAT Th Tyrosine 3-monooxygenase 8.37e-41 0.32
GRIA1_MOUSE Gria1 Glutamate receptor 1 8.831e-40 0.32
KYNU_RAT Kynu Kynureninase 1.157e-39 0.31
LUXS_ECOLI luxS S-ribosylhomocysteine lyase 1.381e-38 0.31
LUXS_VIBCB luxS S-ribosylhomocysteine lyase 1.381e-38 0.31
GLT_PYRHO Glutamate transporter homolog 2.83e-38 0.30
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 2.62e-37 0.43
MURI_LACFE murI Glutamate racemase 1.332e-36 0.29
GRIA4_HUMAN GRIA4 Glutamate receptor 4 9.948e-36 0.39
GRIA3_RAT Gria3 Glutamate receptor 3 1.521e-35 0.33
GRIA3_HUMAN GRIA3 Glutamate receptor 3 3.616e-35 0.33
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 7.604e-33 0.59
LUXS_BACSU luxS S-ribosylhomocysteine lyase 8.33e-33 0.31
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 2.598e-32 0.48
GRIA4_RAT Gria4 Glutamate receptor 4 6.393e-31 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.008e-30 0.44
ARGI1_RAT Arg1 Arginase-1 1.3e-30 0.38
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 2.003e-28 0.46
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.052e-26 0.31
DAPE_HAEIN dapE Succinyl-diaminopimelate desuccinylase 5.827e-26 0.32
B9V8S1_XENLA grik2.L Ionotropic glutamate receptor subunit GluR6(Q) 3.516e-24 0.30
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 2.847e-23 0.29
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 5.518e-23 0.28
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.144e-22 0.29
GRIA2_HUMAN GRIA2 Glutamate receptor 2 1.633e-22 0.38
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.321e-21 0.38
TY3H_HUMAN TH Tyrosine 3-monooxygenase 2.588e-20 0.32
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 3.559e-20 0.36
AMPN_ECOLI pepN Aminopeptidase N 1.608e-19 0.31
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 2.434e-19 0.44
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 4.468e-19 0.43
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.915e-17 0.35
GRIA1_RAT Gria1 Glutamate receptor 1 1.11e-16 0.36
NOS2_RAT Nos2 Nitric oxide synthase, inducible 1.11e-16 0.37
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.22e-16 0.31
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 9.992e-16 0.41
1A15_ARATH ACS5 1-aminocyclopropane-1-carboxylate synthase 5 2.665e-15 0.29
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 3.22e-15 0.38
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 7.105e-15 0.37
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 9.77e-15 0.48
NEP_MOUSE Mme Neprilysin 2.298e-14 0.31
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 2.998e-14 0.35
NOS1_MOUSE Nos1 Nitric oxide synthase, brain 2.842e-12 0.34
CGL_HUMAN CTH Cystathionine gamma-lyase 6.464e-12 0.29
AMPB_HUMAN RNPEP Aminopeptidase B 1.105e-10 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.38e-10 0.55
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 9.77e-10 0.32
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 1.634e-09 0.37
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 4.037e-09 0.43
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 4.373e-09 0.37
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 4.498e-09 0.37
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 7.329e-09 0.31
DCOR_RAT Odc1 Ornithine decarboxylase 9.518e-09 0.35
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 9.771e-08 0.30
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.297e-07 0.41
AMPB_RAT Rnpep Aminopeptidase B 2.041e-07 0.30
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 5.772e-07 0.32
NOS1_RAT Nos1 Nitric oxide synthase, brain 1.735e-06 0.37
KMO_RAT Kmo Kynurenine 3-monooxygenase 2.322e-06 0.36
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 2.368e-06 0.35

Flunarizine

CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 9.4e-117 1.00
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.3e-110 1.00
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.964e-97 1.00
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.629e-39 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.325e-21 1.00
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.457e-20 1.00
OPRD_HUMAN OPRD1 Delta-type opioid receptor 6.661e-16 1.00
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.438e-15 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 8.993e-15 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 9.388e-13 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.622e-12 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.51e-11 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.812e-11 1.00
RCE1_YEAST RCE1 CAAX prenyl protease 2 3.118e-11 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 3.299e-11 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.247e-10 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 4.074e-09 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 6.569e-09 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.084e-08 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 4.384e-08 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 8.462e-08 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.914e-07 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 6.375e-06 1.00
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 1.204e-05 1.00
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 4.079e-05 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 4.211e-05 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.839e-05 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.0004261 1.00
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 0.0007809 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.000956 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.001297 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.003564 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.007402 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.01364 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.04697 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.05982 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.07102 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.1416 1.00
CNR1_HUMAN CNR1 Cannabinoid receptor 1 0.6363 1.00
STRP_STRP1 ska Streptokinase A 0.7642 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.8476 1.00
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 1.976e-76 0.38
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 1.976e-76 0.38
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 3.57e-69 0.38
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.052e-49 0.66
GPR4_RAT Gpr4 G-protein coupled receptor 4 8.225e-47 0.33
GPR4_MOUSE Gpr4 G-protein coupled receptor 4 5.968e-41 0.33
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.116e-40 0.66
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.474e-37 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 7.946e-35 0.30
GPR4_HUMAN GPR4 G-protein coupled receptor 4 2.339e-26 0.34
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.946e-25 0.41
GP183_HUMAN GPR183 G-protein coupled receptor 183 2.862e-23 0.41
OPRX_HUMAN OPRL1 Nociceptin receptor 6.458e-21 0.46
MC4R_HUMAN MC4R Melanocortin receptor 4 4.898e-17 0.38
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 6.661e-16 0.35
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 2.442e-15 0.41
MGLL_RAT Mgll Monoglyceride lipase 3.664e-15 0.36
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 7.794e-14 0.33
Q63380_RAT NET Transporter 1.247e-13 0.36
MGLL_MOUSE Mgll Monoglyceride lipase 2.136e-12 0.36
Q9WTR4_RAT Slc6a2 Transporter 2.927e-12 0.36
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.009e-11 0.34
DRD2_MOUSE Drd2 D(2) dopamine receptor 3.894e-11 0.36
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.052e-10 0.36
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.525e-10 0.38
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 6.468e-10 0.31
AHR_RABIT AHR Aryl hydrocarbon receptor 8.347e-10 0.30
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.108e-09 0.29
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 4.55e-09 0.48
MGLL_HUMAN MGLL Monoglyceride lipase 6.174e-09 0.40
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 7.976e-09 0.33
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.339e-07 0.36
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.451e-07 0.36
OPRD_RAT Oprd1 Delta-type opioid receptor 8.3e-07 0.41
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.229e-06 0.30
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.583e-06 0.40
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.025e-06 0.37
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 2.365e-06 0.35
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.037e-06 0.28
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.988e-06 0.30
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 6.299e-06 0.35
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 6.868e-06 0.36

Vildagliptin

DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 8.641e-107 1.00
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 1.136e-74 1.00
SEPR_HUMAN FAP Prolyl endopeptidase FAP 5.597e-70 1.00
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 5.121e-61 1.00
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 3.52e-50 1.00
DPP4_RAT Dpp4 Dipeptidyl peptidase 4 5.05e-48 1.00
O31048_PORGN DPP IV Dipeptidyl peptidase IV 4.135e-20 1.00
SEPR_MOUSE Fap Prolyl endopeptidase FAP 2.467e-181 0.70
PPCE_HUMAN PREP Prolyl endopeptidase 1.407e-91 0.70
PPCE_PIG PREP Prolyl endopeptidase 9.044e-41 0.42
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.234e-28 0.56
Q9S446_STAAU srtA Class A sortase SrtA 4.365e-11 0.31
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.542e-10 0.31
DPP4_PIG DPP4 Dipeptidyl peptidase 4 4.614e-10 0.36
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 1.45e-08 0.34

Phenolphthalein

TYSY_ECOLI thyA Thymidylate synthase 4.265e-98 1.00
TYSY_ENTFA thyA Thymidylate synthase 1.089e-50 1.00
TYSY_LACCA thyA Thymidylate synthase 6.471e-41 1.00
TYSY_HUMAN TYMS Thymidylate synthase 4.384e-07 1.00
GPR55_HUMAN GPR55 G-protein coupled receptor 55 1.183e-05 1.00
TYSY_CRYNB TMP1 Thymidylate synthase 1.186e-131 0.56
C3SWJ7_ECOLX thyA Thymidylate synthase 2.433e-31 0.56
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.523e-18 0.29
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 1.523e-18 0.29
ITPR3_HUMAN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 2.923e-10 0.30
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 1.775e-09 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.44e-08 0.29
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 1.002e-07 0.31
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.106e-07 0.30
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.994e-07 0.28
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 5.622e-07 0.28
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 5.622e-07 0.28
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.338e-06 0.34
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.592e-06 0.32
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.907e-06 0.28
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.959e-06 0.29
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.011e-06 0.62
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.213e-06 0.28

Taurocholic_acid

NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.4e-96 1.00
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 2.286e-88 1.00
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.496e-63 1.00
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 9.713e-83 0.42
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.888e-72 0.72
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 3.028e-68 0.37
BXA1_CLOBO botA Botulinum neurotoxin type A 8.867e-45 0.45
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 4.62e-43 0.81
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 7.077e-42 0.53
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.236e-32 0.35
CAH2_HUMAN CA2 Carbonic anhydrase 2 6.795e-27 0.72
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.025e-26 0.72
NR1H4_HUMAN NR1H4 Bile acid receptor 3.568e-26 0.81
ABCBB_HUMAN ABCB11 Bile salt export pump 9.234e-24 0.60
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.993e-23 0.32
CP125_MYCTU cyp125 Steroid C26-monooxygenase 3.817e-23 0.28
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 2.245e-21 0.34
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.971e-19 0.34
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 6.741e-19 0.30
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 2.22e-15 0.29
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.154e-14 0.55
REST_BORBU resT Telomere resolvase ResT 1.463e-13 0.33
GCR_HUMAN NR3C1 Glucocorticoid receptor 3.205e-10 0.57
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 3.721e-10 0.38
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 6.147e-10 0.38
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.548e-09 0.38
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 1.548e-09 0.38
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 3.554e-09 0.38
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.164e-09 0.30
DPOLB_RAT Polb DNA polymerase beta 6.53e-09 0.44
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.071e-08 0.38
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.071e-08 0.38
VDR_HUMAN VDR Vitamin D3 receptor 1.236e-08 0.44
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.322e-08 0.29
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.497e-08 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 2.062e-08 0.38
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 5.39e-08 0.30
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.502e-08 0.38
MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.076e-07 0.50
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 5.056e-07 0.38
ANDR_HUMAN AR Androgen receptor 6.248e-07 0.50
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.87e-06 0.41
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 1.992e-06 0.30
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 7.745e-06 0.56
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 7.953e-06 0.28

Estrone_sulfate

SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.84e-87 1.00
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 5.121e-61 1.00
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.08e-27 1.00
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 9.905e-10 1.00
STS_HUMAN STS Steryl-sulfatase 1.506e-171 0.80
CP19A_HUMAN CYP19A1 Aromatase 3.57e-112 0.70
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 8.002e-70 0.70
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 2.014e-69 0.48
Q95MF8_PIG Sulfotransferase 6.191e-63 0.36
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.028e-55 0.36
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.668e-40 0.45
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.974e-40 0.70
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 7.718e-40 0.36
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.663e-35 0.67
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.96e-31 0.70
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 8.66e-29 0.46
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.312e-27 0.44
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 2.261e-25 0.34
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.558e-23 0.38
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.419e-20 0.33
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 1.147e-17 0.44
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 1.722e-17 0.36
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 8.882e-16 0.32
ESR1_HUMAN ESR1 Estrogen receptor 2.554e-15 0.80
ESR1_MOUSE Esr1 Estrogen receptor 1.02e-13 0.44
ESR2_MOUSE Esr2 Estrogen receptor beta 1.02e-13 0.44
Q690N0_BOVIN PGR Progesterone receptor 1.696e-13 0.70
ESR2_HUMAN ESR2 Estrogen receptor beta 1.3e-11 0.80
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.842e-11 0.39
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.844e-09 0.44
ESR1_RAT Esr1 Estrogen receptor 8.973e-09 0.44
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.414e-08 0.34
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.077e-08 0.41
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 4.455e-08 0.32
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 2.617e-07 0.28
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.109e-07 0.30
ANDR_RAT Ar Androgen receptor 4.918e-07 0.70
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 8.806e-07 0.65
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.419e-06 0.44
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 4.176e-06 0.70
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 7.013e-06 0.54
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 7.705e-06 0.28

Febuxostat

XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 7.403e-83 1.00
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 3.324e-27 1.00
XDH_RAT Xdh Xanthine dehydrogenase/oxidase 1.377e-17 1.00
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.862e-50 0.56
MAX_HUMAN MAX Protein max 8.416e-44 0.35
PPARD_CANLF PPARD Peroxisome proliferator-activated receptor delta 5.239e-40 0.32
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.575e-35 0.42
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 1.148e-31 0.33
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 1.039e-27 0.42
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.375e-23 0.41
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.191e-21 0.43
GRIA4_HUMAN GRIA4 Glutamate receptor 4 2.514e-17 0.31
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 1.11e-16 0.33
PPGB_HUMAN CTSA Lysosomal protective protein 1.11e-16 0.36
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.109e-15 0.67
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 8.939e-12 0.40
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 1.06e-11 0.31
TESK2_HUMAN TESK2 Dual specificity testis-specific protein kinase 2 1.339e-11 0.28
RARB_HUMAN RARB Retinoic acid receptor beta 1.664e-11 0.33
RARA_HUMAN RARA Retinoic acid receptor alpha 4.591e-10 0.33
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 3.676e-09 0.32
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 5.058e-09 0.34
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 2.731e-08 0.32
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 6.029e-08 0.38
RARG_HUMAN RARG Retinoic acid receptor gamma 1.802e-07 0.33
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 2.989e-07 0.32
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 3.159e-07 0.31
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 9.396e-07 0.29
EDNRA_RAT Ednra Endothelin-1 receptor 4.896e-06 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 5.266e-06 0.34
MYC_HUMAN MYC Myc proto-oncogene protein 6.119e-06 0.35
GRIA2_HUMAN GRIA2 Glutamate receptor 2 6.312e-06 0.30
PPARA_CANLF PPARA Peroxisome proliferator-activated receptor alpha 6.636e-06 0.32
DCK_HUMAN DCK Deoxycytidine kinase 6.968e-06 0.30

Iloperidone

DRD2_RAT Drd2 D(2) dopamine receptor 7.395e-81 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.05e-46 1.00
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 2.822e-31 1.00
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.377e-17 1.00
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 3.859e-17 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.882e-16 1.00
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 3.097e-11 1.00
CCR3_RAT Ccr3 C-C chemokine receptor type 3 5.938e-122 0.37
ALBU_BOVIN ALB Serum albumin 9.634e-122 0.50
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 2.351e-103 0.37
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 8.057e-85 0.64
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 1.287e-73 0.37
MET_HUMAN MET Hepatocyte growth factor receptor 1.029e-69 0.41
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.376e-67 0.61
HRH1_CAVPO HRH1 Histamine H1 receptor 5.969e-65 0.62
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 1.493e-60 0.36
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.43e-58 0.30
HRH2_HUMAN HRH2 Histamine H2 receptor 9.046e-56 0.46
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 5.112e-54 0.64
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.599e-50 0.33
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.626e-49 0.60
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 2.371e-47 0.40
DRD1_PIG DRD1 D(1A) dopamine receptor 2.09e-43 0.36
HGF_HUMAN HGF Hepatocyte growth factor 4.411e-43 0.33
DRD5_RAT Drd5 D(1B) dopamine receptor 2.759e-40 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.463e-39 0.52
HRH3_RAT Hrh3 Histamine H3 receptor 2.172e-39 0.37
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 6.601e-38 0.33
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.323e-37 0.58
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 1.501e-37 0.34
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.564e-37 0.40
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.043e-32 0.37
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.374e-32 0.62
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.535e-31 0.49
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.168e-30 0.40
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 2.168e-29 0.39
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.101e-28 0.61
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.289e-28 0.61
HRH1_HUMAN HRH1 Histamine H1 receptor 1.329e-27 0.61
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.502e-26 0.46
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 5.563e-25 0.33
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 5.974e-25 0.46
HRH3_HUMAN HRH3 Histamine H3 receptor 1.025e-24 0.37
DRD3_RAT Drd3 D(3) dopamine receptor 1.539e-24 0.62
ATM_HUMAN ATM Serine-protein kinase ATM 1.902e-24 0.34
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.344e-24 0.40
Q53I59_TRYCR PDEC Phosphodiesterase 2.85e-24 0.31
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 4.974e-24 0.61
Q4DCQ3_TRYCC Superoxide dismutase 5.448e-24 0.29
NK1R_CAVPO TACR1 Substance-P receptor 5.751e-24 0.32
H10_HUMAN H1-0 Histone H1.0 1.168e-23 0.46
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 4.156e-23 0.40
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 6.666e-23 0.29
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.142e-22 0.46
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 6.581e-22 0.40
AUKBA_XENLA aurkb-a Aurora kinase B-A 8.933e-22 0.35
ACOD_HUMAN SCD Acyl-CoA desaturase 6.524e-21 0.42
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.128e-20 0.46
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.613e-20 0.32
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 1.878e-20 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.692e-20 0.41
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 4.506e-20 0.46
DRD4_RAT Drd4 D(4) dopamine receptor 7.993e-20 0.39
SCD5_HUMAN SCD5 Stearoyl-CoA desaturase 5 2.621e-19 0.31
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 3.013e-19 0.33
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 9.265e-19 0.40
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.088e-18 0.39
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 1.523e-18 0.29
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.648e-18 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 2.335e-18 0.46
MYO3A_HUMAN MYO3A Myosin-IIIa 4.46e-18 0.40
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 4.749e-18 0.45
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 5.525e-18 0.39
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 7.017e-18 0.40
RON_HUMAN MST1R Macrophage-stimulating protein receptor 7.333e-18 0.41
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 2.898e-17 0.33
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 2.943e-17 0.40
MYO3B_HUMAN MYO3B Myosin-IIIb 3.448e-17 0.40
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.382e-17 0.36
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 4.629e-17 0.40
CHLE_HORSE BCHE Cholinesterase 5.208e-17 0.38
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 5.386e-17 0.57
ACES_ELEEL ache Acetylcholinesterase 1.11e-16 0.56
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.11e-16 0.40
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.11e-16 0.34
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 1.11e-16 0.40
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 1.11e-16 0.40
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.22e-16 0.40
BLK_MOUSE Blk Tyrosine-protein kinase Blk 3.331e-16 0.31
DRD1_RAT Drd1 D(1A) dopamine receptor 4.441e-16 0.58
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 6.661e-16 0.34
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 9.992e-16 0.40
IRAK3_HUMAN IRAK3 Interleukin-1 receptor-associated kinase 3 1.11e-15 0.40
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.221e-15 0.46
AURKA_HUMAN AURKA Aurora kinase A 1.221e-15 0.40
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 2.331e-15 0.40
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 2.665e-15 0.40
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 3.109e-15 0.36
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 3.442e-15 0.33
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.997e-15 0.53
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 4.33e-15 0.40
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.996e-15 0.33
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 5.662e-15 0.34
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 5.773e-15 0.40
M3K3_HUMAN MAP3K3 Mitogen-activated protein kinase kinase kinase 3 5.773e-15 0.40
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 6.994e-15 0.40
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 7.55e-15 0.39
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 8.216e-15 0.32
SIK2_HUMAN SIK2 Serine/threonine-protein kinase SIK2 8.216e-15 0.40
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 2.121e-14 0.40
SSR5_MOUSE Sstr5 Somatostatin receptor type 5 2.631e-14 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.519e-14 0.46
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 4.097e-14 0.32
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 4.43e-14 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 7.183e-14 0.58
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 7.605e-14 0.40
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 9.392e-14 0.31
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.104e-13 0.40
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.191e-13 0.39
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 1.32e-13 0.40
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 1.463e-13 0.33
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 1.503e-13 0.40
CTRO_HUMAN CIT Citron Rho-interacting kinase 1.53e-13 0.40
M3K2_HUMAN MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1.53e-13 0.40
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 1.53e-13 0.40
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.56e-13 0.29
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.62e-13 0.40
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 2.421e-13 0.40
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.494e-13 0.36
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 4.018e-13 0.40
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 4.018e-13 0.40
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 4.6e-13 0.40
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.228e-13 0.35
OGA_RAT Oga Protein O-GlcNAcase 5.476e-13 0.28
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 5.906e-13 0.35
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 6.161e-13 0.62
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 6.187e-13 0.37
DRD1_HUMAN DRD1 D(1A) dopamine receptor 7.284e-13 0.48
CDK16_HUMAN CDK16 Cyclin-dependent kinase 16 8.871e-13 0.40
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.941e-13 0.40
MEN1_HUMAN MEN1 Menin 1.07e-12 0.31
E2AK1_HUMAN EIF2AK1 Eukaryotic translation initiation factor 2-alpha kinase 1 1.138e-12 0.40
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 1.195e-12 0.40
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.325e-12 0.40
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 2.011e-12 0.32
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.111e-12 0.40
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.297e-12 0.40
NORA_STAAU norA Quinolone resistance protein NorA 2.75e-12 0.33
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 2.868e-12 0.40
Q8MMZ8_EIMTE cGMP-dependent protein kinase 3.736e-12 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.953e-12 0.39
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.502e-12 0.30
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 4.716e-12 0.40
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 4.998e-12 0.40
FPTA_PSEAE fptA Fe(3+)-pyochelin receptor 6.254e-12 0.29
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 6.528e-12 0.31
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 9.7e-12 0.29
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 1.031e-11 0.40
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 1.605e-11 0.40
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1.683e-11 0.31
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.016e-11 0.37
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 2.64e-11 0.40
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 2.811e-11 0.30
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 3.543e-11 0.40
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.76e-11 0.46
NK2R_MOUSE Tacr2 Substance-K receptor 4.238e-11 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 4.698e-11 0.40
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 5.263e-11 0.40
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 5.834e-11 0.33
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 7.038e-11 0.48
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.213e-10 0.33
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.352e-10 0.40
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 1.472e-10 0.28
NEK11_HUMAN NEK11 Serine/threonine-protein kinase Nek11 1.517e-10 0.31
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.638e-10 0.32
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 2.05e-10 0.40
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 2.1e-10 0.32
DMPK_HUMAN DMPK Myotonin-protein kinase 2.366e-10 0.33
CSK_HUMAN CSK Tyrosine-protein kinase CSK 2.638e-10 0.40
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 4.343e-10 0.40
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 4.343e-10 0.40
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 4.343e-10 0.40
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 4.343e-10 0.40
ACES_MOUSE Ache Acetylcholinesterase 5.09e-10 0.31
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.409e-10 0.40
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 5.409e-10 0.40
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 6.214e-10 0.41
MK06_HUMAN MAPK6 Mitogen-activated protein kinase 6 6.557e-10 0.33
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 6.557e-10 0.33
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 7.157e-10 0.33
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 7.924e-10 0.40
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.104e-09 0.35
PHKG1_HUMAN PHKG1 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1.185e-09 0.33
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.295e-09 0.40
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.383e-09 0.40
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 1.941e-09 0.40
ACES_RAT Ache Acetylcholinesterase 2.043e-09 0.56
GAK_HUMAN GAK Cyclin-G-associated kinase 3.917e-09 0.34
TEC_HUMAN TEC Tyrosine-protein kinase Tec 4.126e-09 0.40
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 4.791e-09 0.40
RENI_CALJA REN Renin 5.129e-09 0.30
DRD5_HUMAN DRD5 D(1B) dopamine receptor 6.339e-09 0.46
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 6.845e-09 0.40
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 6.884e-09 0.40
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 8.213e-09 0.40
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 9.61e-09 0.35
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 1.006e-08 0.33
MK14_MOUSE Mapk14 Mitogen-activated protein kinase 14 1.051e-08 0.31
TLK2_HUMAN TLK2 Serine/threonine-protein kinase tousled-like 2 1.083e-08 0.31
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 1.303e-08 0.34
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.443e-08 0.40
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 1.545e-08 0.40
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.593e-08 0.40
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 2.193e-08 0.41
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 2.335e-08 0.32
AURKB_HUMAN AURKB Aurora kinase B 2.371e-08 0.40
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.825e-08 0.40
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 3.012e-08 0.31
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 3.012e-08 0.31
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 3.012e-08 0.31
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 3.428e-08 0.46
ACES_HUMAN ACHE Acetylcholinesterase 4.108e-08 0.56
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 4.816e-08 0.32
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 5.018e-08 0.32
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 5.115e-08 0.36
INSRR_HUMAN INSRR Insulin receptor-related protein 5.218e-08 0.40
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 5.218e-08 0.40
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 7.347e-08 0.31
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 7.347e-08 0.31
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 7.912e-08 0.29
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 8.817e-08 0.46
MK11_MOUSE Mapk11 Mitogen-activated protein kinase 11 9.157e-08 0.29
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 9.16e-08 0.40
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 9.229e-08 0.41
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.031e-07 0.29
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 1.35e-07 0.28
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 1.539e-07 0.40
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 1.595e-07 0.40
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 1.612e-07 0.31
TLK1_HUMAN TLK1 Serine/threonine-protein kinase tousled-like 1 1.612e-07 0.31
AURKC_HUMAN AURKC Aurora kinase C 1.674e-07 0.40
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.786e-07 0.31
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1.874e-07 0.40
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.038e-07 0.46
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 2.392e-07 0.40
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 2.43e-07 0.31
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 3.244e-07 0.31
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 3.244e-07 0.31
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.409e-07 0.33
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 3.881e-07 0.40
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 3.881e-07 0.40
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 4.198e-07 0.40
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 4.242e-07 0.40
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 4.767e-07 0.40
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 5.876e-07 0.40
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 6.378e-07 0.40
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 7.881e-07 0.29
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 8.73e-07 0.29
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 9.458e-07 0.40
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 9.867e-07 0.40
M3K11_HUMAN MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1.007e-06 0.40
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.069e-06 0.31
PI42C_HUMAN PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1.526e-06 0.40
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.567e-06 0.30
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 1.751e-06 0.40
NR1H4_MOUSE Nr1h4 Bile acid receptor 2.102e-06 0.30
CHLE_HUMAN BCHE Cholinesterase 2.237e-06 0.36
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 2.414e-06 0.40
Q5TKS5_STAAU fabI Enoyl-ACP reductase 2.415e-06 0.28
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.583e-06 0.40
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 3.656e-06 0.40
PLD1_RAT Pld1 Phospholipase D1 3.933e-06 0.30
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 3.95e-06 0.31
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 4.399e-06 0.31
M3K9_HUMAN MAP3K9 Mitogen-activated protein kinase kinase kinase 9 4.693e-06 0.40
PLD2_HUMAN PLD2 Phospholipase D2 4.869e-06 0.30
Q8WQX9_9TRYP PDEB1 Phosphodiesterase 5.278e-06 0.31
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 7.079e-06 0.40
HRH3_CAVPO HRH3 Histamine H3 receptor 7.52e-06 0.39
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 9.449e-06 0.31

Estriol

SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 6.368e-80 1.00
SHBG_HUMAN SHBG Sex hormone-binding globulin 7.876e-46 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.379e-36 1.00
ESR1_HUMAN ESR1 Estrogen receptor 3.997e-36 1.00
ESR2_HUMAN ESR2 Estrogen receptor beta 5.797e-33 1.00
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.716e-08 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.3819 1.00
STS_HUMAN STS Steryl-sulfatase 1.314e-163 0.69
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.237e-86 0.69
Q95MF8_PIG Sulfotransferase 1.829e-80 0.48
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 5.687e-45 0.73
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 3.715e-42 0.56
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 9.635e-40 0.62
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 3.672e-37 0.73
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 1.131e-34 0.48
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.442e-33 0.54
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 7.335e-29 0.73
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 2.312e-27 0.44
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 3.343e-26 0.32
ESR1_MOUSE Esr1 Estrogen receptor 2.634e-22 0.73
ESR2_MOUSE Esr2 Estrogen receptor beta 2.634e-22 0.73
ADCY5_RAT Adcy5 Adenylate cyclase type 5 2.585e-19 0.36
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 2.813e-19 0.73
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.945e-19 0.52
SECA1_STAA8 secA1 Protein translocase subunit SecA 1 3.334e-18 0.29
Q690N0_BOVIN PGR Progesterone receptor 5.551e-16 0.73
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.443e-15 0.47
ESR1_RAT Esr1 Estrogen receptor 5.329e-15 0.73
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 6.106e-15 0.73
CP19A_HUMAN CYP19A1 Aromatase 1.446e-11 0.62
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.508e-11 0.28
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.748e-10 0.73
ANDR_RAT Ar Androgen receptor 5.323e-09 0.73
ESR2_RAT Esr2 Estrogen receptor beta 1.216e-08 0.73
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 8.261e-08 0.73
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.039e-07 0.47
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 1.848e-07 0.33
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.697e-07 0.58
DRD2_BOVIN DRD2 D(2) dopamine receptor 2.366e-06 0.33
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.92e-06 0.45

Lorcaserin

5HT2C_CANLF HTR2C 5-hydroxytryptamine receptor 2C 2.714e-79 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 6.102e-33 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 5.547e-27 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.188e-17 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.336e-08 1.00
PNMT_BOVIN PNMT Phenylethanolamine N-methyltransferase 7.119e-31 0.35
PNMT_HUMAN PNMT Phenylethanolamine N-methyltransferase 1.526e-20 0.50
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.266e-18 0.35
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 1.11e-16 0.36
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.22e-16 0.32
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 4.552e-15 0.35
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 5.562e-14 0.32
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 1.891e-09 0.35
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 2.774e-09 0.32
DRD1_RAT Drd1 D(1A) dopamine receptor 4.807e-09 0.36
5HT3A_MOUSE Htr3a 5-hydroxytryptamine receptor 3A 4.652e-08 0.30
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 4.79e-08 0.28
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.311e-07 0.40
TAA7B_RAT Taar7b Trace amine-associated receptor 7b 1.625e-07 0.31
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 4.676e-07 0.32
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 3.059e-06 0.33
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.46e-06 0.39
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 4.414e-06 0.34
HRH1_RAT Hrh1 Histamine H1 receptor 5.352e-06 0.32

Deoxycholic_acid

GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 6.042e-76 1.00
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.078e-38 1.00
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 6.102e-107 0.61
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 1.476e-101 0.54
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.851e-84 0.61
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 2.109e-79 0.47
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 1.66e-70 0.33
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 1.146e-65 0.37
CAH4_BOVIN CA4 Carbonic anhydrase 4 6.566e-58 0.65
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 2.202e-54 0.54
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 2.154e-53 0.33
GBRA4_RAT Gabra4 Gamma-aminobutyric acid receptor subunit alpha-4 2.355e-52 0.37
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.37e-47 0.53
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.877e-46 0.55
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 7.877e-45 0.36
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 1.073e-41 0.37
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 4.019e-37 0.41
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 5.244e-33 0.41
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.548e-31 0.48
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 2.685e-30 0.30
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 4.608e-29 0.36
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.211e-27 0.47
SHBG_RAT Shbg Sex hormone-binding globulin 1.343e-26 0.33
CP125_MYCTU cyp125 Steroid C26-monooxygenase 2.505e-26 0.32
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 2.614e-25 0.31
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 5.667e-25 0.32
NR1H4_HUMAN NR1H4 Bile acid receptor 9.248e-25 0.77
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 3.873e-24 0.39
REST_BORBU resT Telomere resolvase ResT 7.465e-23 0.58
IF4A1_MOUSE Eif4a1 Eukaryotic initiation factor 4A-I 2.958e-22 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.656e-21 0.65
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 3.565e-21 0.34
CAH1_HUMAN CA1 Carbonic anhydrase 1 9.55e-21 0.63
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.593e-20 0.48
ABCBB_HUMAN ABCB11 Bile salt export pump 3.199e-20 0.51
NMDE3_HUMAN GRIN2C Glutamate receptor ionotropic, NMDA 2C 1.985e-19 0.31
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 8.104e-18 0.28
NMDE4_HUMAN GRIN2D Glutamate receptor ionotropic, NMDA 2D 3.331e-16 0.31
DPOLB_RAT Polb DNA polymerase beta 3.664e-15 0.77
UD2B7_HUMAN UGT2B7 UDP-glucuronosyltransferase 2B7 4.119e-14 0.33
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 5.485e-14 0.47
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 4.378e-12 0.47
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.167e-11 0.40
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 1.397e-11 0.31
Q2TU57_MAIZE Sterol-8,7-isomerase 1.397e-11 0.31
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.949e-11 0.46
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.479e-11 0.39
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 3.442e-11 0.46
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 9.802e-11 0.46
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 9.802e-11 0.46
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.904e-10 0.35
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 2.513e-10 0.46
ANDR_RAT Ar Androgen receptor 2.938e-10 0.48
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 3.229e-10 0.41
RORA_HUMAN RORA Nuclear receptor ROR-alpha 7.387e-10 0.32
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 8.765e-10 0.46
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 8.765e-10 0.46
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 9.651e-10 0.47
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.281e-09 0.46
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.841e-09 0.46
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.085e-09 0.39
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 2.195e-09 0.39
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.677e-09 0.48
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 2.948e-09 0.47
ECR_DROME EcR Ecdysone receptor 3.998e-09 0.32
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 9.158e-09 0.46
LICH_HUMAN LIPA Lysosomal acid lipase/cholesteryl ester hydrolase 1.083e-08 0.31
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 5.166e-08 0.40
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 6.545e-08 0.47
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6.567e-08 0.34
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 6.891e-08 0.46
VDR_HUMAN VDR Vitamin D3 receptor 1.424e-07 0.77
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 3.148e-07 0.53
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 8.948e-07 0.31
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 2.572e-06 0.61
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.437e-06 0.38
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.843e-06 0.44
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 5.824e-06 0.74
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 8.632e-06 0.61

Flibanserin

5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.379e-72 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.947e-37 1.00
PLD1_RAT Pld1 Phospholipase D1 1.32e-97 0.35
RMLC_MYCTO rmlC dTDP-4-dehydrorhamnose 3,5-epimerase 1.142e-77 0.33
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.237e-66 0.71
PLD2_HUMAN PLD2 Phospholipase D2 1.926e-55 0.35
HDP_PLAF7 HDP Heme ligase 1.882e-51 0.41
PLD1_HUMAN PLD1 Phospholipase D1 1.117e-48 0.35
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 4.445e-48 0.56
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 1.189e-47 0.38
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.449e-45 0.48
TERT_RAT Tert Telomerase reverse transcriptase 3.537e-44 0.35
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.024e-42 0.44
DRD2_RAT Drd2 D(2) dopamine receptor 3.349e-38 0.52
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 4.863e-36 0.36
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.349e-30 0.56
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.679e-30 0.57
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 6.058e-28 0.34
PDS_SYNE7 pds 15-cis-phytoene desaturase 6.966e-28 0.37
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.264e-27 0.48
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.963e-26 0.52
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.639e-25 0.41
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.011e-25 0.52
LYSC1_RAT Lyz1 Lysozyme C-1 2.158e-24 0.30
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 2.403e-24 0.56
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 6.005e-24 0.56
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 7.721e-23 0.34
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.912e-22 0.47
DRD3_RAT Drd3 D(3) dopamine receptor 1.765e-21 0.45
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.392e-20 0.45
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 4.466e-20 0.37
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.996e-20 0.51
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.052e-19 0.55
BGLR_RAT Gusb Beta-glucuronidase 6.741e-19 0.30
EBPL_HUMAN EBPL Emopamil-binding protein-like 6.741e-19 0.30
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 7.277e-19 0.34
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 8.871e-18 0.32
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.149e-17 0.37
MAOX_HUMAN ME1 NADP-dependent malic enzyme 3.331e-17 0.43
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 1.11e-16 0.32
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.11e-16 0.32
KCMA1_RAT Kcnma1 Calcium-activated potassium channel subunit alpha-1 1.11e-16 0.32
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 9.992e-16 0.56
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.11e-15 0.52
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.998e-15 0.57
ZAP70_MOUSE Zap70 Tyrosine-protein kinase ZAP-70 4.441e-15 0.29
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.799e-14 0.36
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 3.445e-13 0.35
BMX_MOUSE Bmx Cytoplasmic tyrosine-protein kinase BMX 3.922e-13 0.29
LYN_MOUSE Lyn Tyrosine-protein kinase Lyn 3.922e-13 0.29
MET_MOUSE Met Hepatocyte growth factor receptor 3.922e-13 0.29
RON_MOUSE Mst1r Macrophage-stimulating protein receptor 3.922e-13 0.29
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 9.533e-13 0.30
TLR7_HUMAN TLR7 Toll-like receptor 7 5.153e-12 0.33
MK09_MOUSE Mapk9 Mitogen-activated protein kinase 9 9.7e-12 0.29
RET_MOUSE Ret Proto-oncogene tyrosine-protein kinase receptor Ret 9.7e-12 0.29
ROS1_MOUSE Ros1 Proto-oncogene tyrosine-protein kinase ROS 9.7e-12 0.29
TIE1_MOUSE Tie1 Tyrosine-protein kinase receptor Tie-1 9.7e-12 0.29
OPRX_HUMAN OPRL1 Nociceptin receptor 2.799e-11 0.36
CALM_BOVIN CALM Calmodulin 3.542e-11 0.30
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.311e-11 0.41
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 8.921e-11 0.47
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 1.068e-10 0.31
FLT3_MOUSE Flt3 Receptor-type tyrosine-protein kinase FLT3 1.105e-10 0.29
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.19e-10 0.32
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 3.757e-10 0.32
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 4.398e-10 0.29
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 7.386e-10 0.41
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 7.541e-10 0.29
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 1.104e-09 0.28
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.537e-09 0.46
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.89e-09 0.36
ELNE_HUMAN ELANE Neutrophil elastase 1.922e-09 0.34
Q76129_9HIV1 gag Structural capsid protein 5.139e-09 0.32
RGS4_HUMAN RGS4 Regulator of G-protein signaling 4 5.348e-09 0.39
DRD1_HUMAN DRD1 D(1A) dopamine receptor 7.365e-09 0.50
Q3Y5H1_9GAMC 3C-like protease 7.775e-09 0.48
GALR3_HUMAN GALR3 Galanin receptor type 3 1.173e-08 0.41
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.593e-08 0.58
CALM1_HUMAN CALM1 Calmodulin-1 1.709e-08 0.30
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.561e-08 0.41
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.014e-08 0.44
ERG2_YEAST ERG2 C-8 sterol isomerase 4.225e-08 0.32
DRD4_RAT Drd4 D(4) dopamine receptor 7.053e-08 0.34
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 7.511e-08 0.35
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 7.757e-08 0.33
WDR48_HUMAN WDR48 WD repeat-containing protein 48 9.989e-08 0.34
INSR_MOUSE Insr Insulin receptor 1.031e-07 0.29
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.36e-07 0.34
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.245e-07 0.31
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 2.36e-07 0.34
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 2.531e-07 0.36
DRD1_RAT Drd1 D(1A) dopamine receptor 4.599e-07 0.46
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 5.563e-07 0.41
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.012e-07 0.32
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 1.182e-06 0.41
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.316e-06 0.40
OXDA_HUMAN DAO D-amino-acid oxidase 1.843e-06 0.37
OXDA_MOUSE Dao D-amino-acid oxidase 1.886e-06 0.31
OXDA_PIG DAO D-amino-acid oxidase 2.062e-06 0.35
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 2.185e-06 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.817e-06 0.34
RXFP1_HUMAN RXFP1 Relaxin receptor 1 3.367e-06 0.32
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 3.462e-06 0.29
TNFA_HUMAN TNF Tumor necrosis factor 3.657e-06 0.38
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 3.679e-06 0.34
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.813e-06 0.34
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 4.091e-06 0.33
ADCY5_RAT Adcy5 Adenylate cyclase type 5 5.463e-06 0.28
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 8.028e-06 0.31

Fluspirilene

OPRX_HUMAN OPRL1 Nociceptin receptor 7.493e-68 1.00
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 1.11e-15 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.253e-07 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.245e-06 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.1e-05 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.157e-05 1.00
XBP1_HUMAN XBP1 X-box-binding protein 1 0.000332 1.00
DNAB_MYCTU dnaB Replicative DNA helicase 0.1212 1.00
PLD2_HUMAN PLD2 Phospholipase D2 2.527e-126 0.53
PLD1_HUMAN PLD1 Phospholipase D1 1.401e-121 0.52
OPRX_RAT Oprl1 Nociceptin receptor 2.955e-105 0.50
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 4.396e-54 0.68
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.342e-47 0.41
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.213e-42 0.41
DRD4_RAT Drd4 D(4) dopamine receptor 9.257e-42 0.51
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.045e-37 0.68
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.901e-36 0.65
DRD5_HUMAN DRD5 D(1B) dopamine receptor 9.261e-31 0.47
CASB_RAT Csn2 Beta-casein 4.625e-30 0.68
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.248e-28 0.68
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 1.657e-28 0.65
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.695e-28 0.50
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.159e-27 0.42
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 2.133e-27 0.53
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.288e-26 0.33
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.313e-25 0.72
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.912e-24 0.41
DRD2_RAT Drd2 D(2) dopamine receptor 2.95e-24 0.68
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.223e-24 0.38
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.541e-24 0.47
DRD1_PIG DRD1 D(1A) dopamine receptor 4.482e-24 0.33
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 8.538e-24 0.72
Q63380_RAT NET Transporter 9.2e-24 0.38
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.129e-23 0.38
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.141e-23 0.65
DRD3_CHLAE DRD3 D(3) dopamine receptor 2.604e-22 0.51
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 7.119e-22 0.47
NK2R_RAT Tacr2 Substance-K receptor 4.546e-21 0.32
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 3.411e-20 0.47
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 5.121e-20 0.39
DRD1_MOUSE Drd1 D(1A) dopamine receptor 5.72e-20 0.70
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.619e-19 0.49
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.999e-19 0.30
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.043e-18 0.68
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.419e-18 0.68
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.83e-18 0.70
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 9.19e-18 0.42
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.538e-17 0.68
H10_HUMAN H1-0 Histone H1.0 3.332e-17 0.33
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.551e-16 0.68
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 2.776e-15 0.29
DRD2_CHLAE DRD2 D(2) dopamine receptor 5.174e-14 0.51
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.874e-13 0.68
DRD1_HUMAN DRD1 D(1A) dopamine receptor 6.282e-13 0.68
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.124e-12 0.48
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.313e-12 0.42
MC4R_HUMAN MC4R Melanocortin receptor 4 1.749e-12 0.35
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.885e-12 0.70
HRH2_HUMAN HRH2 Histamine H2 receptor 1.986e-12 0.47
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.379e-12 0.68
HRH1_HUMAN HRH1 Histamine H1 receptor 2.525e-12 0.48
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 3.63e-12 0.30
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 5.348e-12 0.35
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 6.181e-12 0.43
DRD2_MOUSE Drd2 D(2) dopamine receptor 3.897e-11 0.35
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 5.592e-11 0.68
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.507e-10 0.33
DRD5_RAT Drd5 D(1B) dopamine receptor 6.538e-10 0.29
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 8.973e-10 0.33
DRD1_RAT Drd1 D(1A) dopamine receptor 1.748e-09 0.38
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 7.788e-09 0.68
Q9WTR4_RAT Slc6a2 Transporter 1.184e-08 0.38
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.658e-08 0.55
ERG2_YEAST ERG2 C-8 sterol isomerase 2.81e-08 0.33
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 4.182e-08 0.68
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 4.59e-08 0.47
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 1.07e-07 0.30
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.549e-07 0.30
VKOR1_RAT Vkorc1 Vitamin K epoxide reductase complex subunit 1 1.91e-07 0.30
LEF_BACAN lef Lethal factor 1.991e-07 0.36
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.254e-07 0.33
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.426e-07 0.38
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 6.152e-07 0.33
OPRM_RAT Oprm1 Mu-type opioid receptor 1.516e-06 0.53
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.546e-06 0.68
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 1.7e-06 0.30
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.026e-06 0.33
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 3.07e-06 0.32
HRH1_CAVPO HRH1 Histamine H1 receptor 4.244e-06 0.33
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.99e-06 0.29

Mepenzolate

ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.492e-66 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.073e-38 1.00
Q8WMX0_BOVIN Muscarinic receptor M1 1.051e-75 0.46
AMYP_RAT Amy2 Pancreatic alpha-amylase 9.142e-72 0.34
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 3.335e-60 0.48
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 8.636e-36 0.50
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 5.758e-32 0.60
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.255e-31 0.60
Q8WSF8_APLCA Soluble acetylcholine receptor 8.445e-31 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 9.115e-28 0.46
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.513e-26 0.64
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 8.424e-22 0.31
ACHP_LYMST Acetylcholine-binding protein 4.538e-19 0.33
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 1.224e-18 0.36
ABHDB_HUMAN ABHD11 Protein ABHD11 2.576e-18 0.29
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 6.81e-18 0.64
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 9.104e-15 0.64
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.009e-12 0.60
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 6.464e-12 0.29
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 7.655e-11 0.29
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.801e-09 0.50
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 5.153e-09 0.33
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 9.002e-08 0.29
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 2.772e-07 0.40

Tetrabenazine

VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.352e-58 1.00
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.735e-32 1.00
HCN2_MOUSE Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 5.334e-59 0.37
DRD1_HUMAN DRD1 D(1A) dopamine receptor 8.009e-51 0.55
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 7.521e-48 0.62
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 2.097e-43 0.62
HCN1_MOUSE Hcn1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 3.522e-42 0.37
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 3.804e-27 0.35
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 2.242e-25 0.35
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 3.115e-21 0.34
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 5.679e-21 0.40
ACES_MOUSE Ache Acetylcholinesterase 1.061e-19 0.32
TF_HUMAN F3 Tissue factor 1.079e-18 0.51
DRD1_RAT Drd1 D(1A) dopamine receptor 1.11e-16 0.52
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 1.11e-16 0.46
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.22e-16 0.43
DRD5_HUMAN DRD5 D(1B) dopamine receptor 6.661e-16 0.51
ACES_RAT Ache Acetylcholinesterase 8.774e-13 0.33
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 9.659e-13 0.41
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 9.914e-12 0.37
ACES_HUMAN ACHE Acetylcholinesterase 2.265e-11 0.37
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 3.974e-11 0.51
CAH14_HUMAN CA14 Carbonic anhydrase 14 4.723e-11 0.35
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 6.414e-11 0.40
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.133e-10 0.41
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 1.517e-10 0.31
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 7.626e-09 0.32
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 9.917e-09 0.32
OX2R_HUMAN HCRTR2 Orexin receptor type 2 1.508e-08 0.38
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.846e-08 0.38
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.497e-08 0.55
Q9JKC1_RAT Bche Carboxylic ester hydrolase 4.98e-08 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.027e-08 0.46
FDFT_HUMAN FDFT1 Squalene synthase 5.724e-08 0.33
KLK7_HUMAN KLK7 Kallikrein-7 1.111e-07 0.53
KCNN3_HUMAN KCNN3 Small conductance calcium-activated potassium channel protein 3 1.361e-07 0.41
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.743e-07 0.35
ACPM_BOVIN NDUFAB1 Acyl carrier protein, mitochondrial 2.472e-07 0.35
NDUV1_BOVIN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 2.472e-07 0.35
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 9.629e-07 0.53
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.342e-06 0.51
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.358e-06 0.28
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.397e-06 0.37
DRD2_RAT Drd2 D(2) dopamine receptor 3.155e-06 0.52
ACES_BOVIN ACHE Acetylcholinesterase 4.967e-06 0.32

Berberine

ACES_ELEEL ache Acetylcholinesterase 9.049e-57 1.00
CHLE_HORSE BCHE Cholinesterase 2.033e-48 1.00
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.617e-08 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.08263 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.09988 1.00
CHLE_HUMAN BCHE Cholinesterase 0.4887 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.7183 1.00
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.503e-61 0.77
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.819e-40 0.48
VE2_HPV1 E2 Regulatory protein E2 1.215e-35 0.28
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 4.212e-24 0.30
RGS17_HUMAN RGS17 Regulator of G-protein signaling 17 2.952e-20 0.32
Q9XSW7_PIG Phosphodiesterase 1.211e-18 0.30
XBP1_RAT Xbp1 X-box-binding protein 1 1.565e-14 0.32
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 6.917e-14 0.45
TF_HUMAN F3 Tissue factor 4.686e-09 0.34
Q49PX0_9POXV N1L N1L 9.971e-09 0.31
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 2.668e-08 0.31
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.058e-08 0.28
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.14e-07 0.35
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 3.991e-06 0.64

Doconexent

OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 2.339e-51 1.00
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 4.857e-06 1.00
A3QR02_CHISP est1 Carboxylic ester hydrolase 1.317e-63 0.40
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 6.12e-55 0.55
LOXX_SOYBN LOX1.4 Seed linoleate 9S-lipoxygenase 2.374e-54 0.43
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 1.52e-40 0.32
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.52e-40 0.32
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.06e-33 0.55
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 6.567e-29 0.32
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 4.633e-23 0.28
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 4.633e-23 0.28
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 1.94e-21 0.37
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 2.44e-18 0.36
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 5.836e-18 0.71
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 7.088e-18 0.28
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.11e-16 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.532e-14 0.36
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.865e-14 0.33
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 9.238e-13 0.29
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 5.566e-11 0.32
MGLL_RAT Mgll Monoglyceride lipase 5.971e-11 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 6.177e-11 0.32
Q6RY99_RAT Tetraspanin 1.105e-10 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.266e-10 0.34
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 2.404e-09 0.44
TLR2_HUMAN TLR2 Toll-like receptor 2 3.831e-09 0.34
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.771e-08 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.816e-08 0.29
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 8.044e-08 0.32
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.291e-07 0.44
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 6.132e-07 0.34
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 9.911e-07 0.32
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.195e-06 0.29
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 1.618e-06 0.32
PTGIS_HUMAN PTGIS Prostacyclin synthase 2.07e-06 0.28
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 2.226e-06 0.31
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.341e-06 0.49
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 5.108e-06 0.57
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 5.16e-06 0.28
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.838e-06 0.31
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 8.041e-06 0.32

Bifonazole

CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.788e-44 1.00
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 9.774e-19 1.00
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 2.06e-05 1.00
PA21B_HUMAN PLA2G1B Phospholipase A2 0.001746 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.01651 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 0.04827 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 0.4604 1.00
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 6.268e-97 0.71
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 2.094e-59 0.44
CP19A_RAT Cyp19a1 Aromatase 7.901e-57 0.83
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.12e-44 0.37
CP19A_HUMAN CYP19A1 Aromatase 4.559e-36 0.83
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 7.069e-34 0.73
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 9.576e-27 0.44
HMOX1_RAT Hmox1 Heme oxygenase 1 5.349e-25 0.44
THAS_RAT Tbxas1 Thromboxane-A synthase 1.751e-23 0.32
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 2.75e-22 0.73
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.031e-20 0.35
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 3.079e-10 0.43
MGLL_RAT Mgll Monoglyceride lipase 2.183e-08 0.40
ADHX_HUMAN ADH5 Alcohol dehydrogenase class-3 2.185e-08 0.34
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.318e-08 0.45
SKN1_CAEEL skn-1 Protein skinhead-1 1.626e-07 0.50
HMOX2_RAT Hmox2 Heme oxygenase 2 4.43e-07 0.38
MGLL_MOUSE Mgll Monoglyceride lipase 6.746e-07 0.40
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 8.092e-07 0.30
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.347e-06 0.31

Milnacipran

SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.79e-40 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.119e-30 1.00
Q63380_RAT NET Transporter 1.586e-17 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.355e-11 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 9.97e-10 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 3.167e-25 0.28
NK3R_HUMAN TACR3 Neuromedin-K receptor 6.581e-25 0.36
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.11e-16 0.35
OPRX_HUMAN OPRL1 Nociceptin receptor 4.441e-16 0.37
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.443e-15 0.38
Q9WTR4_RAT Slc6a2 Transporter 2.931e-14 0.76
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 3.719e-13 0.35
O77773_PIG Voltage-dependent calcium channel alpha-2 delta subunit 7.701e-11 0.30
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.093e-10 0.37
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.536e-09 0.76
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.572e-08 0.35
Q17SB2_PLAFA Plasmepsin 4 2.596e-08 0.33
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.59e-07 0.37
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 2.887e-07 0.32
OPRD_HUMAN OPRD1 Delta-type opioid receptor 6.434e-07 0.33
TSPO_HUMAN TSPO Translocator protein 1.256e-06 0.31
TSPO_RAT Tspo Translocator protein 1.401e-06 0.32
CHLE_MOUSE Bche Cholinesterase 5.79e-06 0.31
Q8I6Z5_PLAF7 Plasmepsin V 9.1e-06 0.33

Cyproterone_acetate

Q690N0_BOVIN PGR Progesterone receptor 4.909e-37 1.00
ANDR_RAT Ar Androgen receptor 1.729e-08 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 0.006655 1.00
ANDR_HUMAN AR Androgen receptor 0.03055 1.00
AA1R_RAT Adora1 Adenosine receptor A1 0.8224 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 0.9986 1.00
UB2D3_HUMAN UBE2D3 Ubiquitin-conjugating enzyme E2 D3 1.704e-13 0.29

Clioquinol

COMT_RAT Comt Catechol O-methyltransferase 8.52e-32 1.00
Q8IL32_PLAF7 Heat shock protein 90, putative 2.858e-30 1.00
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 2.603e-17 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.422e-08 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.1918 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.8917 1.00
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 3.421e-47 0.42
AMPL_YEAST APE1 Vacuolar aminopeptidase 1 5.023e-46 0.37
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 1.509e-38 0.72
BXA1_CLOBO botA Botulinum neurotoxin type A 2.931e-35 0.54
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 5.186e-34 0.57
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.677e-28 0.39
BXA1_CLOBH botA Botulinum neurotoxin type A 3.509e-28 0.48
LMP1_EBVB9 LMP1 Latent membrane protein 1 5.74e-21 0.47
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 4.996e-15 0.38
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.266e-14 0.36
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.799e-14 0.36
STRP_STRP1 ska Streptokinase A 3.176e-13 0.72
EZRI_HUMAN EZR Ezrin 1.508e-11 0.28
COMT_HUMAN COMT Catechol O-methyltransferase 1.988e-11 0.36
Q7ZJM1_9HIV1 pol Integrase 8.57e-11 0.35
A3KMY8_BOVIN GUSB Beta-glucuronidase 3.819e-10 0.33
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5.395e-10 0.48
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.828e-09 0.32
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.889e-09 0.33
VP16_HHV11 Tegument protein VP16 1.66e-08 0.49
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.293e-08 0.33
PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 5.837e-08 0.45
KLF5_HUMAN KLF5 Krueppel-like factor 5 7.433e-08 0.41
T23O_MOUSE Tdo2 Tryptophan 2,3-dioxygenase 1.178e-07 0.38
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 4.108e-07 0.32
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 5.884e-07 0.54
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.589e-07 0.36

Huperzine_A

ACES_TETCF ache Acetylcholinesterase 2.823e-31 1.00
ACES_RAT Ache Acetylcholinesterase 4.336e-28 1.00
ACES_BOVIN ACHE Acetylcholinesterase 3.068e-13 1.00
ACES_HUMAN ACHE Acetylcholinesterase 5.353e-09 1.00
ACES_MOUSE Ache Acetylcholinesterase 1.21e-05 1.00
CHLE_HUMAN BCHE Cholinesterase 0.4887 1.00
ACES_ELEEL ache Acetylcholinesterase 0.9235 1.00

Caprylic_acid

TLR2_HUMAN TLR2 Toll-like receptor 2 1.778e-29 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.839e-23 1.00
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.774e-19 1.00
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.257e-08 1.00
GPR84_HUMAN GPR84 G-protein coupled receptor 84 6.874e-05 1.00
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 3.022e-155 0.59
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 8.414e-128 0.45
A1ZA98_DROME Jhe Carboxylic ester hydrolase 8.756e-103 0.52
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.441e-89 0.46
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 9.991e-87 0.37
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 5.666e-85 0.46
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.097e-84 0.37
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.695e-82 0.38
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 7.841e-81 0.39
Q9MYX2_PIG CPT1 Carnitine palmitoyl transferase I liver isoform 5.405e-75 0.40
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 2.312e-74 0.65
EST5_RAT Liver carboxylesterase B-1 1.14e-70 0.34
PLB1_CRYNB PLB1 Phospholipase B 5.639e-69 0.36
Q9GPG0_MANSE Carboxylic ester hydrolase 1.317e-68 0.52
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 2.387e-67 0.35
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 2.274e-64 0.37
EST1_PIG Liver carboxylesterase 6.538e-64 0.52
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 1.333e-63 0.35
KDM7A_HUMAN KDM7A Lysine-specific demethylase 7A 2.172e-62 0.39
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 2.948e-61 0.48
CP4F2_HUMAN CYP4F2 Cytochrome P450 4F2 4.15e-60 0.48
LYAM3_MOUSE Selp P-selectin 8.213e-58 0.29
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.785e-57 0.37
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 5.734e-57 0.45
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.734e-57 0.45
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 8.63e-56 0.34
Q95Z89_LEIMA Top1B DNA topoisomerase type IB small subunit 1.011e-55 0.44
Q6UB75_PIG Group VII phospholipase A2 1.207e-55 0.50
GSHR_PLAF7 GR3 Glutathione reductase 1.383e-55 0.35
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 7.867e-55 0.42
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 2.035e-54 0.35
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 2.339e-54 0.37
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 9.185e-54 0.43
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 3.94e-52 0.35
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 4.056e-52 0.33
SC6A8_RAT Slc6a8 Sodium- and chloride-dependent creatine transporter 1 2.78e-51 0.32
LASR_PSEAE lasR Transcriptional activator protein LasR 2.499e-50 0.42
CERT_HUMAN CERT1 Ceramide transfer protein 3.077e-50 0.40
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 4.665e-50 0.38
EST2_HUMAN CES2 Cocaine esterase 3.256e-49 0.65
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 7.397e-49 0.40
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.933e-48 0.31
EST1_RABIT Liver carboxylesterase 1 1.7e-47 0.65
CP4A4_RABIT CYP4A4 Cytochrome P450 4A4 3.737e-47 0.38
A3QR02_CHISP est1 Carboxylic ester hydrolase 5.346e-47 0.29
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 9.669e-47 0.49
ACER2_HUMAN ACER2 Alkaline ceramidase 2 2.422e-46 0.37
DYN1_HUMAN DNM1 Dynamin-1 2.637e-46 0.42
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 3.081e-46 0.32
LYAM1_MOUSE Sell L-selectin 1.112e-45 0.29
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 2.009e-45 0.35
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 2.13e-45 0.31
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.714e-44 0.45
ADH7_HUMAN ADH7 All-trans-retinol dehydrogenase [NAD(+)] ADH7 1.353e-43 0.35
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.562e-42 0.62
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 2.779e-42 0.30
EST1_HUMAN CES1 Liver carboxylesterase 1 4.151e-41 0.65
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 1.421e-39 0.33
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 2.302e-39 0.52
DPOLM_HUMAN POLM DNA-directed DNA/RNA polymerase mu 4.474e-39 0.31
MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 4.474e-39 0.31
PA2A1_NAJMO Acidic phospholipase A2 CM-I 4.474e-39 0.31
TDT_BOVIN DNTT DNA nucleotidylexotransferase 4.474e-39 0.31
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 1.2e-38 0.35
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 3.458e-38 0.30
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.738e-37 0.34
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 2.395e-37 0.31
LUXR_ALIFS luxR Transcriptional activator protein LuxR 3.098e-36 0.34
LYAM2_MOUSE Sele E-selectin 3.875e-36 0.29
PSB6_YEAST PRE7 Proteasome subunit beta type-6 3.875e-36 0.29
SGPL1_RAT Sgpl1 Sphingosine-1-phosphate lyase 1 3.875e-36 0.29
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 5.447e-36 0.43
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 1.807e-35 0.33
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.723e-35 0.45
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 1.067e-34 0.43
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.204e-34 0.58
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 1.78e-34 0.43
ERG1_RAT Sqle Squalene monooxygenase 5.238e-34 0.32
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 9.4e-34 0.42
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 4.946e-33 0.36
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 9.687e-33 0.37
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 9.391e-32 0.40
PPCE_RAT Prep Prolyl endopeptidase 3.726e-31 0.33
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 3.801e-31 0.36
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.535e-30 0.44
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.119e-30 0.29
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.147e-29 0.43
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.289e-29 0.36
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.391e-29 0.35
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.442e-29 0.52
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 4.299e-29 0.52
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 8.093e-28 0.43
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.008e-27 0.56
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.372e-27 0.44
Q5HMD9_STAEQ murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 2.669e-26 0.32
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 2.091e-25 0.46
TRAR_RHIRD traR Transcriptional activator protein TraR 2.94e-25 0.34
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 3.82e-25 0.40
POLI_MOUSE Poli DNA polymerase iota 3.865e-25 0.31
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 7.752e-25 0.38
KPCA_RAT Prkca Protein kinase C alpha type 1.013e-23 0.33
DXS_ECO27 dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.239e-23 0.29
DXS_MYCTU dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.239e-23 0.29
PPAF_PHAVU Fe(3+)-Zn(2+) purple acid phosphatase 1.605e-23 0.29
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.704e-23 0.45
NSMA_HUMAN SMPD2 Sphingomyelin phosphodiesterase 2 2.847e-23 0.29
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.457e-22 0.74
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 1.064e-21 0.32
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.128e-21 0.37
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 3.392e-21 0.34
LYAM1_HUMAN SELL L-selectin 3.834e-21 0.29
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.989e-20 0.34
AMPN_ECOLI pepN Aminopeptidase N 2.318e-20 0.32
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 4.22e-20 0.32
KPCL_MOUSE Prkch Protein kinase C eta type 6.772e-20 0.38
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 9.411e-20 0.40
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 1.122e-19 0.48
O07911_STAAU agrC AgrC 1.175e-19 0.38
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 1.193e-19 0.31
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 1.446e-19 0.31
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 1.643e-19 0.52
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 1.832e-19 0.35
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 7.925e-19 0.52
PHLC_BACCE plc Phospholipase C 1.133e-18 0.28
D5FGE8_TRYCR POT1.5 Putative amino acid permease/transporter 1.265e-18 0.30
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 2.576e-18 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 3.263e-18 0.35
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.555e-18 0.74
PSB5_YEAST PRE2 Proteasome subunit beta type-5 4.879e-18 0.29
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 6.307e-18 0.34
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 9.174e-18 0.39
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.033e-17 0.42
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.981e-17 0.45
Q6RY99_RAT Tetraspanin 2.857e-17 0.48
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.11e-16 0.35
ACEA_CANAX ICL1 Isocitrate lyase 3.331e-16 0.31
POLH_HUMAN POLH DNA polymerase eta 3.331e-16 0.31
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 5.551e-16 0.48
FAS_RAT Fasn Fatty acid synthase 6.661e-16 0.32
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 7.772e-16 0.43
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 9.992e-16 0.35
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 1.332e-15 0.34
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.887e-15 0.32
LSS_RAT Lss Lanosterol synthase 3.22e-15 0.35
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 3.331e-15 0.45
THB_HUMAN THRB Thyroid hormone receptor beta 3.553e-15 0.41
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 5.218e-15 0.47
REST_BORBU resT Telomere resolvase ResT 1.01e-14 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.055e-14 0.46
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.243e-14 0.55
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.565e-14 0.32
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.787e-14 0.41
LYAM3_HUMAN SELP P-selectin 1.843e-14 0.36
DPEP1_PIG DPEP1 Dipeptidase 1 1.976e-14 0.32
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.531e-14 0.48
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 7.905e-14 0.43
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 7.905e-14 0.44
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.215e-13 0.38
THA_HUMAN THRA Thyroid hormone receptor alpha 1.233e-13 0.41
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.404e-13 0.35
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.45e-13 0.32
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 1.783e-13 0.37
ECR_BOMMO EcR Ecdysone receptor 2.287e-13 0.36
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 2.462e-13 0.48
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 3.13e-13 0.35
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.444e-13 0.37
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.586e-13 0.32
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 1.169e-12 0.31
POLK_HUMAN POLK DNA polymerase kappa 1.191e-12 0.31
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.203e-12 0.37
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 2.324e-12 0.47
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 2.951e-12 0.40
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 3.497e-12 0.30
ALF_CANAL FBA1 Fructose-bisphosphate aldolase 4.114e-12 0.30
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 6.124e-12 0.29
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 6.464e-12 0.29
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 8.284e-12 0.35
DPOLB_HUMAN POLB DNA polymerase beta 9.07e-12 0.42
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.425e-11 0.44
B6TK44_MAIZE Cycloeucalenol cycloisomerase 1.437e-11 0.28
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.502e-11 0.36
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 1.762e-11 0.49
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 1.882e-11 0.45
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.121e-11 0.57
KPCA_HUMAN PRKCA Protein kinase C alpha type 4.429e-11 0.38
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 4.573e-11 0.56
KPCA_BOVIN PRKCA Protein kinase C alpha type 4.579e-11 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 8.53e-11 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 9.526e-11 0.45
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.07e-10 0.38
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.286e-10 0.35
Q2TU57_MAIZE Sterol-8,7-isomerase 1.577e-10 0.28
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 2.305e-10 0.39
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.877e-10 0.33
MEP2_YEAST MEP2 Ammonium transporter MEP2 4.084e-10 0.29
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 6.157e-10 0.50
PI2R_HUMAN PTGIR Prostacyclin receptor 7.924e-10 0.37
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 8.483e-10 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 8.524e-10 0.36
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.18e-09 0.43
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.389e-09 0.74
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 1.497e-09 0.31
MGLL_MOUSE Mgll Monoglyceride lipase 1.537e-09 0.35
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.561e-09 0.47
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.968e-09 0.39
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 3.258e-09 0.45
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.419e-09 0.36
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 4.595e-09 0.39
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 6.485e-09 0.45
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 7.167e-09 0.33
DPOLL_HUMAN POLL DNA polymerase lambda 9.718e-09 0.31
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.532e-08 0.35
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.301e-08 0.31
AMPL_HUMAN LAP3 Cytosol aminopeptidase 3.53e-08 0.33
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 3.831e-08 0.38
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 4.585e-08 0.45
KPCD_MOUSE Prkcd Protein kinase C delta type 4.72e-08 0.35
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 6.161e-08 0.45
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 6.987e-08 0.46
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 7.105e-08 0.32
Q8ST54_TRYCR HK Phosphotransferase 1.084e-07 0.34
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.767e-07 0.41
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 3.03e-07 0.38
MGLL_RAT Mgll Monoglyceride lipase 3.616e-07 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 3.854e-07 0.47
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.48e-07 0.29
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 8.227e-07 0.29
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 1.164e-06 0.41
Q8IL32_PLAF7 Heat shock protein 90, putative 1.244e-06 0.54
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.248e-06 0.71
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.285e-06 0.44
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 1.454e-06 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.57e-06 0.47
DPOLB_RAT Polb DNA polymerase beta 1.653e-06 0.31
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.79e-06 0.30
ACLY_RAT Acly ATP-citrate synthase 3.596e-06 0.33
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 3.946e-06 0.74
PA21B_HUMAN PLA2G1B Phospholipase A2 5.464e-06 0.32
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.875e-06 0.29
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 7.259e-06 0.45
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 8.053e-06 0.29
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 9.626e-06 0.34

Palmitic_Acid

TLR2_HUMAN TLR2 Toll-like receptor 2 1.778e-29 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.839e-23 1.00
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.774e-19 1.00
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.257e-08 1.00
GPR84_HUMAN GPR84 G-protein coupled receptor 84 6.874e-05 1.00
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 3.022e-155 0.59
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 8.414e-128 0.45
A1ZA98_DROME Jhe Carboxylic ester hydrolase 8.756e-103 0.52
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.441e-89 0.46
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 9.991e-87 0.37
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 5.666e-85 0.46
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.097e-84 0.37
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.695e-82 0.38
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 7.841e-81 0.39
Q9MYX2_PIG CPT1 Carnitine palmitoyl transferase I liver isoform 5.405e-75 0.40
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 2.312e-74 0.65
EST5_RAT Liver carboxylesterase B-1 1.14e-70 0.34
PLB1_CRYNB PLB1 Phospholipase B 5.639e-69 0.36
Q9GPG0_MANSE Carboxylic ester hydrolase 1.317e-68 0.52
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 2.387e-67 0.35
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 2.274e-64 0.37
EST1_PIG Liver carboxylesterase 6.538e-64 0.52
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 1.333e-63 0.35
KDM7A_HUMAN KDM7A Lysine-specific demethylase 7A 2.172e-62 0.39
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 2.948e-61 0.48
CP4F2_HUMAN CYP4F2 Cytochrome P450 4F2 4.15e-60 0.48
LYAM3_MOUSE Selp P-selectin 8.213e-58 0.29
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.785e-57 0.37
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 5.734e-57 0.45
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.734e-57 0.45
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 8.63e-56 0.34
Q95Z89_LEIMA Top1B DNA topoisomerase type IB small subunit 1.011e-55 0.44
Q6UB75_PIG Group VII phospholipase A2 1.207e-55 0.50
GSHR_PLAF7 GR3 Glutathione reductase 1.383e-55 0.35
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 7.867e-55 0.42
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 2.035e-54 0.35
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 2.339e-54 0.37
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 9.185e-54 0.43
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 3.94e-52 0.35
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 4.056e-52 0.33
SC6A8_RAT Slc6a8 Sodium- and chloride-dependent creatine transporter 1 2.78e-51 0.32
LASR_PSEAE lasR Transcriptional activator protein LasR 2.499e-50 0.42
CERT_HUMAN CERT1 Ceramide transfer protein 3.077e-50 0.40
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 4.665e-50 0.38
EST2_HUMAN CES2 Cocaine esterase 3.256e-49 0.65
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 7.397e-49 0.40
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 1.933e-48 0.31
EST1_RABIT Liver carboxylesterase 1 1.7e-47 0.65
CP4A4_RABIT CYP4A4 Cytochrome P450 4A4 3.737e-47 0.38
A3QR02_CHISP est1 Carboxylic ester hydrolase 5.346e-47 0.29
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 9.669e-47 0.49
ACER2_HUMAN ACER2 Alkaline ceramidase 2 2.422e-46 0.37
DYN1_HUMAN DNM1 Dynamin-1 2.637e-46 0.42
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 3.081e-46 0.32
LYAM1_MOUSE Sell L-selectin 1.112e-45 0.29
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 2.009e-45 0.35
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 2.13e-45 0.31
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.714e-44 0.45
ADH7_HUMAN ADH7 All-trans-retinol dehydrogenase [NAD(+)] ADH7 1.353e-43 0.35
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.562e-42 0.62
Q964Q8_TRYCR SPPS Solanesyl diphosphate synthase 2.779e-42 0.30
EST1_HUMAN CES1 Liver carboxylesterase 1 4.151e-41 0.65
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 1.421e-39 0.33
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 2.302e-39 0.52
DPOLM_HUMAN POLM DNA-directed DNA/RNA polymerase mu 4.474e-39 0.31
MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 4.474e-39 0.31
PA2A1_NAJMO Acidic phospholipase A2 CM-I 4.474e-39 0.31
TDT_BOVIN DNTT DNA nucleotidylexotransferase 4.474e-39 0.31
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 1.2e-38 0.35
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 3.458e-38 0.30
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.738e-37 0.34
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 2.395e-37 0.31
LUXR_ALIFS luxR Transcriptional activator protein LuxR 3.098e-36 0.34
LYAM2_MOUSE Sele E-selectin 3.875e-36 0.29
PSB6_YEAST PRE7 Proteasome subunit beta type-6 3.875e-36 0.29
SGPL1_RAT Sgpl1 Sphingosine-1-phosphate lyase 1 3.875e-36 0.29
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 5.447e-36 0.43
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 1.807e-35 0.33
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.723e-35 0.45
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 1.067e-34 0.43
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.204e-34 0.58
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 1.78e-34 0.43
ERG1_RAT Sqle Squalene monooxygenase 5.238e-34 0.32
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 9.4e-34 0.42
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 4.946e-33 0.36
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 9.687e-33 0.37
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 9.391e-32 0.40
PPCE_RAT Prep Prolyl endopeptidase 3.726e-31 0.33
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 3.801e-31 0.36
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.535e-30 0.44
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.119e-30 0.29
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.147e-29 0.43
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.289e-29 0.36
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.391e-29 0.35
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.442e-29 0.52
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 4.299e-29 0.52
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 8.093e-28 0.43
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.008e-27 0.56
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.372e-27 0.44
Q5HMD9_STAEQ murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 2.669e-26 0.32
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 2.091e-25 0.46
TRAR_RHIRD traR Transcriptional activator protein TraR 2.94e-25 0.34
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 3.82e-25 0.40
POLI_MOUSE Poli DNA polymerase iota 3.865e-25 0.31
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 7.752e-25 0.38
KPCA_RAT Prkca Protein kinase C alpha type 1.013e-23 0.33
DXS_ECO27 dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.239e-23 0.29
DXS_MYCTU dxs 1-deoxy-D-xylulose-5-phosphate synthase 1.239e-23 0.29
PPAF_PHAVU Fe(3+)-Zn(2+) purple acid phosphatase 1.605e-23 0.29
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.704e-23 0.45
NSMA_HUMAN SMPD2 Sphingomyelin phosphodiesterase 2 2.847e-23 0.29
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.457e-22 0.74
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 1.064e-21 0.32
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.128e-21 0.37
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 3.392e-21 0.34
LYAM1_HUMAN SELL L-selectin 3.834e-21 0.29
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.989e-20 0.34
AMPN_ECOLI pepN Aminopeptidase N 2.318e-20 0.32
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 4.22e-20 0.32
KPCL_MOUSE Prkch Protein kinase C eta type 6.772e-20 0.38
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 9.411e-20 0.40
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 1.122e-19 0.48
O07911_STAAU agrC AgrC 1.175e-19 0.38
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 1.193e-19 0.31
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 1.446e-19 0.31
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 1.643e-19 0.52
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 1.832e-19 0.35
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 7.925e-19 0.52
PHLC_BACCE plc Phospholipase C 1.133e-18 0.28
D5FGE8_TRYCR POT1.5 Putative amino acid permease/transporter 1.265e-18 0.30
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 2.576e-18 0.29
RARB_HUMAN RARB Retinoic acid receptor beta 3.263e-18 0.35
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.555e-18 0.74
PSB5_YEAST PRE2 Proteasome subunit beta type-5 4.879e-18 0.29
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 6.307e-18 0.34
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 9.174e-18 0.39
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.033e-17 0.42
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.981e-17 0.45
Q6RY99_RAT Tetraspanin 2.857e-17 0.48
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.11e-16 0.35
ACEA_CANAX ICL1 Isocitrate lyase 3.331e-16 0.31
POLH_HUMAN POLH DNA polymerase eta 3.331e-16 0.31
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 5.551e-16 0.48
FAS_RAT Fasn Fatty acid synthase 6.661e-16 0.32
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 7.772e-16 0.43
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 9.992e-16 0.35
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 1.332e-15 0.34
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.887e-15 0.32
LSS_RAT Lss Lanosterol synthase 3.22e-15 0.35
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 3.331e-15 0.45
THB_HUMAN THRB Thyroid hormone receptor beta 3.553e-15 0.41
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 5.218e-15 0.47
REST_BORBU resT Telomere resolvase ResT 1.01e-14 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.055e-14 0.46
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.243e-14 0.55
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 1.565e-14 0.32
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.787e-14 0.41
LYAM3_HUMAN SELP P-selectin 1.843e-14 0.36
DPEP1_PIG DPEP1 Dipeptidase 1 1.976e-14 0.32
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.531e-14 0.48
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 7.905e-14 0.43
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 7.905e-14 0.44
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.215e-13 0.38
THA_HUMAN THRA Thyroid hormone receptor alpha 1.233e-13 0.41
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.404e-13 0.35
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.45e-13 0.32
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 1.783e-13 0.37
ECR_BOMMO EcR Ecdysone receptor 2.287e-13 0.36
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 2.462e-13 0.48
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 3.13e-13 0.35
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.444e-13 0.37
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.586e-13 0.32
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 1.169e-12 0.31
POLK_HUMAN POLK DNA polymerase kappa 1.191e-12 0.31
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 1.203e-12 0.37
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 2.324e-12 0.47
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 2.951e-12 0.40
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 3.497e-12 0.30
ALF_CANAL FBA1 Fructose-bisphosphate aldolase 4.114e-12 0.30
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 6.124e-12 0.29
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 6.464e-12 0.29
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 8.284e-12 0.35
DPOLB_HUMAN POLB DNA polymerase beta 9.07e-12 0.42
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.425e-11 0.44
B6TK44_MAIZE Cycloeucalenol cycloisomerase 1.437e-11 0.28
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.502e-11 0.36
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 1.762e-11 0.49
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 1.882e-11 0.45
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.121e-11 0.57
KPCA_HUMAN PRKCA Protein kinase C alpha type 4.429e-11 0.38
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 4.573e-11 0.56
KPCA_BOVIN PRKCA Protein kinase C alpha type 4.579e-11 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 8.53e-11 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 9.526e-11 0.45
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.07e-10 0.38
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.286e-10 0.35
Q2TU57_MAIZE Sterol-8,7-isomerase 1.577e-10 0.28
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 2.305e-10 0.39
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.877e-10 0.33
MEP2_YEAST MEP2 Ammonium transporter MEP2 4.084e-10 0.29
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 6.157e-10 0.50
PI2R_HUMAN PTGIR Prostacyclin receptor 7.924e-10 0.37
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 8.483e-10 0.32
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 8.524e-10 0.36
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.18e-09 0.43
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.389e-09 0.74
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 1.497e-09 0.31
MGLL_MOUSE Mgll Monoglyceride lipase 1.537e-09 0.35
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.561e-09 0.47
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.968e-09 0.39
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 3.258e-09 0.45
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.419e-09 0.36
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 4.595e-09 0.39
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 6.485e-09 0.45
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 7.167e-09 0.33
DPOLL_HUMAN POLL DNA polymerase lambda 9.718e-09 0.31
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.532e-08 0.35
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.301e-08 0.31
AMPL_HUMAN LAP3 Cytosol aminopeptidase 3.53e-08 0.33
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 3.831e-08 0.38
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 4.585e-08 0.45
KPCD_MOUSE Prkcd Protein kinase C delta type 4.72e-08 0.35
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 6.161e-08 0.45
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 6.987e-08 0.46
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 7.105e-08 0.32
Q8ST54_TRYCR HK Phosphotransferase 1.084e-07 0.34
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.767e-07 0.41
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 3.03e-07 0.38
MGLL_RAT Mgll Monoglyceride lipase 3.616e-07 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 3.854e-07 0.47
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.48e-07 0.29
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 8.227e-07 0.29
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 1.164e-06 0.41
Q8IL32_PLAF7 Heat shock protein 90, putative 1.244e-06 0.54
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.248e-06 0.71
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.285e-06 0.44
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 1.454e-06 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.57e-06 0.47
DPOLB_RAT Polb DNA polymerase beta 1.653e-06 0.31
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.79e-06 0.30
ACLY_RAT Acly ATP-citrate synthase 3.596e-06 0.33
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 3.946e-06 0.74
PA21B_HUMAN PLA2G1B Phospholipase A2 5.464e-06 0.32
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.875e-06 0.29
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 7.259e-06 0.45
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 8.053e-06 0.29
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 9.626e-06 0.34

Nomifensine

Q9WTR4_RAT Slc6a2 Transporter 1.948e-27 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.399e-24 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 5.718e-24 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 6.919e-23 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.144e-19 1.00
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.551e-16 1.00
Q63380_RAT NET Transporter 9.96e-06 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.02198 1.00
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 9.226e-70 0.40
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.365e-55 0.40
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 9.305e-54 0.67
SL9A3_RAT Slc9a3 Sodium/hydrogen exchanger 3 2.237e-33 0.42
IKZF1_HUMAN IKZF1 DNA-binding protein Ikaros 4.879e-18 0.29
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.441e-16 0.47
CRBN_HUMAN CRBN Protein cereblon 4.441e-15 0.29
DRD1_RAT Drd1 D(1A) dopamine receptor 4.474e-14 0.46
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 8.006e-09 0.58
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 2.72e-08 0.35
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.011e-08 0.39
DRD1_CARAU D(1) dopamine receptor 8.255e-08 0.38
DRD1_MOUSE Drd1 D(1A) dopamine receptor 3.299e-07 0.38
SL9A3_HUMAN SLC9A3 Sodium/hydrogen exchanger 3 3.655e-07 0.33
HRH3_HUMAN HRH3 Histamine H3 receptor 5.166e-07 0.39

Oleic_Acid

FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.196e-26 1.00
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 5.185e-10 1.00
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.303e-09 1.00
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 3.146e-07 1.00
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 1.784e-120 0.46
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 5.342e-117 0.70
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 2.064e-94 0.45
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 3.397e-92 0.39
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 9.657e-89 0.88
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 4.404e-88 0.41
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 1.383e-82 0.45
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.302e-82 0.44
Q6UB75_PIG Group VII phospholipase A2 1.959e-81 0.46
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 1.157e-80 0.44
A1ZA98_DROME Jhe Carboxylic ester hydrolase 2.121e-78 0.42
A3QR02_CHISP est1 Carboxylic ester hydrolase 1.115e-74 0.47
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.626e-69 0.51
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 4.851e-63 0.41
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 3.53e-62 0.40
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 1.479e-60 0.41
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.718e-59 0.38
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 3.14e-59 0.44
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 7.993e-59 0.32
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 5.852e-58 0.41
Q9GPG0_MANSE Carboxylic ester hydrolase 1.862e-56 0.42
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 2.106e-55 0.44
CNR1_RAT Cnr1 Cannabinoid receptor 1 7.892e-54 0.70
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 4.681e-51 0.41
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 1.951e-49 0.51
CP4F2_HUMAN CYP4F2 Cytochrome P450 4F2 1.202e-48 0.39
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 1.507e-48 0.41
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.873e-48 0.46
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 6.133e-48 0.50
CERT_HUMAN CERT1 Ceramide transfer protein 1.697e-47 0.38
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 5.023e-46 0.37
Q95Z89_LEIMA Top1B DNA topoisomerase type IB small subunit 9.43e-46 0.36
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 4.974e-45 0.44
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 5.965e-45 0.36
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.965e-45 0.36
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 5.204e-44 0.45
ACER2_HUMAN ACER2 Alkaline ceramidase 2 6.315e-44 0.35
LPAR3_RAT Lpar3 Lysophosphatidic acid receptor 3 6.524e-44 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 6.433e-41 0.63
ADH7_HUMAN ADH7 All-trans-retinol dehydrogenase [NAD(+)] ADH7 1.096e-40 0.32
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 4.208e-40 0.50
CP4A4_RABIT CYP4A4 Cytochrome P450 4A4 7.545e-40 0.32
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 3.765e-38 0.61
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 4.744e-38 0.49
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.039e-37 0.61
MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 1.225e-37 0.30
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 1.015e-36 0.47
SPTC1_HUMAN SPTLC1 Serine palmitoyltransferase 1 1.195e-36 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.653e-36 0.50
EST2_HUMAN CES2 Cocaine esterase 4.13e-36 0.50
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 1.491e-35 0.32
EST1_RABIT Liver carboxylesterase 1 2.812e-35 0.50
LASR_PSEAE lasR Transcriptional activator protein LasR 4.753e-35 0.36
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 5.464e-35 0.30
EST1_PIG Liver carboxylesterase 1.144e-34 0.42
EST5_RAT Liver carboxylesterase B-1 1.698e-32 0.29
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 3.962e-32 0.49
EST1_HUMAN CES1 Liver carboxylesterase 1 4.077e-32 0.61
POLI_MOUSE Poli DNA polymerase iota 6.575e-32 0.40
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.227e-31 0.41
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 3.047e-31 0.30
LUXR_ALIFS luxR Transcriptional activator protein LuxR 3.417e-31 0.33
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 1.927e-30 0.36
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 1.339e-29 0.36
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 2.022e-29 0.36
PLB1_CRYNB PLB1 Phospholipase B 2.535e-29 0.29
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 2.631e-29 0.38
PA1B2_HUMAN PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 5.114e-29 0.36
GSTK1_HUMAN GSTK1 Glutathione S-transferase kappa 1 1.52e-28 0.35
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 2.026e-28 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 2.687e-28 0.47
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 3.787e-28 0.41
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 5.953e-27 0.46
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 6.161e-27 0.30
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.467e-26 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 3.446e-26 0.42
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 4.428e-25 0.36
Q9MYX2_PIG CPT1 Carnitine palmitoyl transferase I liver isoform 7.916e-25 0.42
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.586e-24 0.31
TRAR_RHIRD traR Transcriptional activator protein TraR 9.513e-24 0.33
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.448e-23 0.37
DPEP1_PIG DPEP1 Dipeptidase 1 1.451e-23 0.35
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 2.251e-23 0.36
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 3.107e-23 0.48
KPCA_HUMAN PRKCA Protein kinase C alpha type 7.841e-23 0.47
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 9.993e-23 0.36
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.888e-22 0.42
MGLL_RAT Mgll Monoglyceride lipase 3.643e-22 0.41
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.109e-21 0.40
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.658e-21 0.45
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 3.006e-21 0.30
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 5.943e-21 0.38
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.043e-21 0.74
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 8.432e-21 0.41
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 1.026e-20 0.31
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 1.373e-20 0.41
POLH_HUMAN POLH DNA polymerase eta 1.441e-20 0.40
KDM7A_HUMAN KDM7A Lysine-specific demethylase 7A 2.318e-20 0.32
KPCA_BOVIN PRKCA Protein kinase C alpha type 6.94e-20 0.47
KAPCA_RAT Prkaca cAMP-dependent protein kinase catalytic subunit alpha 1.069e-19 0.38
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 5.19e-19 0.30
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 6.319e-19 0.57
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.224e-18 0.36
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 2.193e-18 0.46
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.44e-18 0.31
D5FGE8_TRYCR POT1.5 Putative amino acid permease/transporter 4.879e-18 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 5.532e-18 0.30
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.07e-17 0.65
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.102e-17 0.45
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 2.175e-17 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.073e-17 0.74
KPCL_MOUSE Prkch Protein kinase C eta type 4.899e-17 0.33
O07911_STAAU agrC AgrC 1.11e-16 0.33
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 2.22e-16 0.43
POLK_HUMAN POLK DNA polymerase kappa 5.551e-16 0.40
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 8.882e-16 0.35
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.554e-15 0.39
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.554e-15 0.39
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.998e-15 0.29
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.22e-15 0.38
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 3.775e-15 0.44
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 4.441e-15 0.29
TLR2_HUMAN TLR2 Toll-like receptor 2 6.106e-15 0.74
CNR1_HUMAN CNR1 Cannabinoid receptor 1 1.121e-14 0.57
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 1.521e-14 0.41
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 2.276e-14 0.31
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.874e-14 0.74
GSHR_PLAF7 GR3 Glutathione reductase 7.55e-14 0.30
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 7.949e-14 0.41
NSMA_RAT Smpd2 Sphingomyelin phosphodiesterase 2 1.027e-13 0.28
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.221e-13 0.50
Q6RY99_RAT Tetraspanin 1.305e-13 0.37
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 4.877e-13 0.39
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.153e-12 0.41
REST_BORBU resT Telomere resolvase ResT 1.4e-12 0.31
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 2.198e-12 0.57
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 3.024e-12 0.41
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 4.108e-12 0.36
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 4.733e-12 0.57
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 1.466e-11 0.56
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 1.792e-11 0.39
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 1.859e-11 0.36
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 2.095e-11 0.41
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 2.236e-11 0.29
PPCE_RAT Prep Prolyl endopeptidase 3.283e-11 0.40
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 3.629e-11 0.48
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 4.095e-11 0.57
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 6.095e-11 0.33
DYN1_HUMAN DNM1 Dynamin-1 6.153e-11 0.39
NAAA_HUMAN NAAA N-acylethanolamine-hydrolyzing acid amidase 6.642e-11 0.36
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 6.662e-11 0.39
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.399e-10 0.47
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 2.98e-10 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.747e-10 0.38
PI2R_HUMAN PTGIR Prostacyclin receptor 7.36e-10 0.38
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 1.045e-09 0.28
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 1.314e-09 0.36
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.136e-09 0.35
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 4.782e-09 0.55
TA2R_RAT Tbxa2r Thromboxane A2 receptor 9.367e-09 0.37
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.319e-08 0.36
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 2.076e-08 0.43
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 2.163e-08 0.46
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 2.389e-08 0.41
LEF_BACAN lef Lethal factor 2.483e-08 0.44
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 4.043e-08 0.36
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 4.168e-08 0.30
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 7.264e-08 0.78
ECR_BOMMO EcR Ecdysone receptor 7.444e-08 0.31
LPAR1_RAT Lpar1 Lysophosphatidic acid receptor 1 9.381e-08 0.33
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 1.031e-07 0.29
KPCA_RAT Prkca Protein kinase C alpha type 1.227e-07 0.28
CNR2_HUMAN CNR2 Cannabinoid receptor 2 1.462e-07 0.57
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.782e-07 0.39
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.848e-07 0.33
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 2.137e-07 0.36
CNR2_RAT Cnr2 Cannabinoid receptor 2 2.212e-07 0.49
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 2.413e-07 0.33
TOP1_HUMAN TOP1 DNA topoisomerase 1 2.62e-07 0.88
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 3.68e-07 0.36
RARB_HUMAN RARB Retinoic acid receptor beta 3.895e-07 0.30
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 6.794e-07 0.33
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 8.045e-07 0.58
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.158e-06 0.45
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 1.166e-06 0.28
MGLL_HUMAN MGLL Monoglyceride lipase 1.194e-06 0.46
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 1.198e-06 0.28
KPCE_HUMAN PRKCE Protein kinase C epsilon type 1.33e-06 0.34
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.349e-06 0.57
DPOLB_HUMAN POLB DNA polymerase beta 1.475e-06 0.39
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 1.487e-06 0.66
Q8ST54_TRYCR HK Phosphotransferase 1.683e-06 0.29
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 2.176e-06 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 2.216e-06 0.39
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 2.422e-06 0.32
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 3.216e-06 0.40
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.217e-06 0.70
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 3.989e-06 0.34
LYAM3_HUMAN SELP P-selectin 6.485e-06 0.35

Phenacetin

CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 4.23e-14 1.00
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 2.128e-73 0.40
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 2.154e-69 0.50
ACRO_HUMAN ACR Acrosin 9.8e-65 0.46
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 8.346e-63 0.34
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.208e-60 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.987e-59 0.44
PSBA_MARPO psbA Photosystem II protein D1 5.649e-56 0.32
O68720_YERPE yopH Targeted effector protein 7.296e-52 0.34
O69638_MYCTO Hydrolase, alpha/beta hydrolase fold family 1.67e-51 0.41
TSHR_HUMAN TSHR Thyrotropin receptor 6.787e-49 0.35
PSBA_SPIOL psbA Photosystem II protein D1 5.695e-46 0.42
THRB_MOUSE F2 Prothrombin 5.739e-46 0.37
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.777e-41 0.40
NMDZ1_MOUSE Grin1 Glutamate receptor ionotropic, NMDA 1 1.841e-40 0.32
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.302e-39 0.56
Q8IL11_PLAF7 M17 leucyl aminopeptidase 2.016e-39 0.59
UT1_RAT Slc14a1 Urea transporter 1 3e-39 0.40
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.086e-38 0.35
Q25615_ONCVO Chitinase 2.258e-38 0.33
EPHB_MYCTO Epoxide hydrolase B 3.653e-38 0.31
Q50565_METTH Carbonic anhydrase 1.225e-37 0.30
D4ADR1_RAT Lpar5 Lysophosphatidic acid receptor 5 4.749e-37 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.124e-36 0.66
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 7.235e-36 0.48
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 2.952e-35 0.38
PRIO_SHEEP PRNP Major prion protein 5.609e-34 0.55
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.911e-33 0.49
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.584e-32 0.42
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.731e-31 0.41
KLK1_HUMAN KLK1 Kallikrein-1 3.38e-31 0.38
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 5.985e-31 0.38
AS3MT_HUMAN AS3MT Arsenite methyltransferase 2.275e-30 0.34
PLMN_MOUSE Plg Plasminogen 1.607e-29 0.37
UROK_RAT Plau Urokinase-type plasminogen activator 1.607e-29 0.37
MYOC_HUMAN MYOC Myocilin 2.586e-28 0.35
KLKB1_HUMAN KLKB1 Plasma kallikrein 3.819e-28 0.39
MYG_HUMAN MB Myoglobin 1.275e-26 0.52
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.019e-25 0.36
LUCI_PHOPY Luciferin 4-monooxygenase 8.146e-25 0.56
NOX1_HUMAN NOX1 NADPH oxidase 1 3.572e-24 0.43
Q86PR3_AEDAE SCP-2 Sterol carrier protein 2 1.605e-23 0.29
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.476e-23 0.39
PDS_SYNE7 pds 15-cis-phytoene desaturase 5.487e-23 0.37
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.44e-23 0.34
ACACA_HUMAN ACACA Acetyl-CoA carboxylase 1 7.054e-23 0.49
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 8.093e-23 0.35
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 9.85e-23 0.34
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.998e-22 0.42
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.39e-21 0.45
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.002e-21 0.37
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 2.491e-21 0.34
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.555e-21 0.45
B4URF0_I33A0 Neuraminidase 7.356e-21 0.57
UT2_RAT Slc14a2 Urea transporter 2 8.931e-21 0.40
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.252e-20 0.53
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.981e-19 0.38
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 2.886e-19 0.31
CAH12_HUMAN CA12 Carbonic anhydrase 12 6.473e-19 0.52
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 6.48e-19 0.29
ANDR_MOUSE Ar Androgen receptor 2.258e-18 0.34
CAH9_HUMAN CA9 Carbonic anhydrase 9 4.63e-18 0.53
CAH1_HUMAN CA1 Carbonic anhydrase 1 4.841e-18 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.03e-18 0.53
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 8.324e-18 0.44
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 1.073e-17 0.45
ANDR_RAT Ar Androgen receptor 1.132e-17 0.40
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.285e-17 0.41
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 2.651e-17 0.37
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 4.11e-17 0.33
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.11e-16 0.37
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 1.11e-16 0.37
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.11e-16 0.48
F262_HUMAN PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 1.11e-16 0.34
MDHM_HUMAN MDH2 Malate dehydrogenase, mitochondrial 1.11e-16 0.38
UROK_MOUSE Plau Urokinase-type plasminogen activator 1.11e-16 0.37
MMP9_RAT Mmp9 Matrix metalloproteinase-9 2.22e-16 0.37
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 4.441e-16 0.38
Q9SPL6_CICIN PPX1 Protoporphyrinogen oxidase 8.882e-16 0.30
Q9XQA6_POAAN psbA Photosystem II protein D1 8.882e-16 0.30
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 9.992e-16 0.35
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 2.442e-15 0.38
CAN_CANAL NCE103 Carbonic anhydrase 2.998e-15 0.45
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 6.106e-15 0.28
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.01e-14 0.35
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 1.199e-14 0.45
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.477e-14 0.33
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.554e-14 0.33
P2RY2_MOUSE P2ry2 P2Y purinoceptor 2 1.599e-14 0.36
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.754e-14 0.52
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.976e-14 0.38
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 2.32e-14 0.45
GATA4_MOUSE Gata4 Transcription factor GATA-4 2.465e-14 0.33
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 2.465e-14 0.33
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 2.731e-14 0.45
TAAR1_RAT Taar1 Trace amine-associated receptor 1 2.831e-14 0.47
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 3.053e-14 0.34
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.209e-14 0.51
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.041e-14 0.31
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 4.197e-14 0.37
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 4.43e-14 0.54
STF1_HUMAN NR5A1 Steroidogenic factor 1 4.996e-14 0.40
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 5.107e-14 0.40
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 9.237e-14 0.40
MTR1B_CHICK Melatonin receptor type 1B 9.992e-14 0.30
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.077e-13 0.35
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.33e-13 0.36
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.912e-13 0.41
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 1.977e-13 0.41
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 3.391e-13 0.31
CDKL1_HUMAN CDKL1 Cyclin-dependent kinase-like 1 4.846e-13 0.28
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 4.967e-13 0.54
MITF_HUMAN MITF Microphthalmia-associated transcription factor 5.053e-13 0.59
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.532e-13 0.38
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 6.424e-13 0.40
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 7.419e-13 0.41
A6QR73_RAT Gpr39 G protein-coupled receptor 39 7.476e-13 0.31
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 8.278e-13 0.33
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 8.321e-13 0.43
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 8.952e-13 0.29
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.238e-12 0.31
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.629e-12 0.61
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.75e-12 0.43
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 1.775e-12 0.35
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.19e-12 0.45
SENP6_HUMAN SENP6 Sentrin-specific protease 6 2.786e-12 0.43
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 3.473e-12 0.54
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 3.582e-12 0.37
Q8MMZ4_PLAFA cGMP-dependent protein kinase 3.82e-12 0.30
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 4.425e-12 0.34
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 5.042e-12 0.40
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 5.13e-12 0.33
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 5.729e-12 0.49
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 6.303e-12 0.40
RXFP1_HUMAN RXFP1 Relaxin receptor 1 7.08e-12 0.31
F261_HUMAN PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 7.566e-12 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 8.695e-12 0.37
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 1.17e-11 0.28
TBB3_HUMAN TUBB3 Tubulin beta-3 chain 1.23e-11 0.28
AHR_RABIT AHR Aryl hydrocarbon receptor 1.646e-11 0.36
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.714e-11 0.43
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 1.834e-11 0.40
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 2.686e-11 0.42
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.779e-11 0.35
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 2.829e-11 0.45
LYOX_HUMAN LOX Protein-lysine 6-oxidase 3.389e-11 0.30
RS27_HUMAN RPS27 40S ribosomal protein S27 4.757e-11 0.30
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 8.18e-11 0.31
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 8.437e-11 0.30
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 8.878e-11 0.29
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.063e-10 0.45
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 1.577e-10 0.47
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.794e-10 0.33
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.887e-10 0.34
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.955e-10 0.36
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.257e-10 0.35
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 2.304e-10 0.36
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 2.389e-10 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.502e-10 0.41
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 2.688e-10 0.39
F13A_HUMAN F13A1 Coagulation factor XIII A chain 4.971e-10 0.31
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 5.218e-10 0.48
XBP1_HUMAN XBP1 X-box-binding protein 1 5.431e-10 0.38
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 5.86e-10 0.40
FURIN_HUMAN FURIN Furin 6.479e-10 0.33
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 6.806e-10 0.39
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.2e-10 0.31
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 8.643e-10 0.39
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 8.811e-10 0.28
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 1.036e-09 0.33
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 1.233e-09 0.47
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 1.297e-09 0.41
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 1.454e-09 0.40
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.595e-09 0.42
UROK_HUMAN PLAU Urokinase-type plasminogen activator 1.796e-09 0.49
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.295e-09 0.41
MMP2_HUMAN MMP2 72 kDa type IV collagenase 2.595e-09 0.43
AOX_TRYBB AOX Alternative oxidase, mitochondrial 2.903e-09 0.29
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.903e-09 0.29
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 2.975e-09 0.38
F263_HUMAN PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 3.006e-09 0.34
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 3.139e-09 0.45
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.942e-09 0.52
GLI1_MOUSE Gli1 Zinc finger protein GLI1 3.959e-09 0.38
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 4.155e-09 0.28
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 4.254e-09 0.41
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 4.856e-09 0.37
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 5.006e-09 0.33
ELOV6_HUMAN ELOVL6 Elongation of very long chain fatty acids protein 6 5.16e-09 0.29
RECA_MYCTU recA Protein RecA 6.881e-09 0.44
REV1_HUMAN REV1 DNA repair protein REV1 7.167e-09 0.33
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 7.188e-09 0.42
A4_HUMAN APP Amyloid-beta precursor protein 8.158e-09 0.33
AOC3_HUMAN AOC3 Membrane primary amine oxidase 8.97e-09 0.35
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 9.593e-09 0.39
STRP_STRP1 ska Streptokinase A 1.004e-08 0.53
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.008e-08 0.41
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.135e-08 0.35
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.201e-08 0.54
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.202e-08 0.41
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 1.224e-08 0.37
HPSE_HUMAN HPSE Heparanase 1.312e-08 0.30
BGLR_HUMAN GUSB Beta-glucuronidase 1.327e-08 0.35
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 1.413e-08 0.50
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.475e-08 0.31
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 1.512e-08 0.28
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 1.512e-08 0.28
SC5A2_MOUSE Slc5a2 Sodium/glucose cotransporter 2 1.589e-08 0.30
AOC1_HUMAN AOC1 Amiloride-sensitive amine oxidase [copper-containing] 1.75e-08 0.30
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 1.805e-08 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.114e-08 0.47
TRY1_HUMAN PRSS1 Trypsin-1 2.208e-08 0.43
LUCI_PHOPE Luciferin 4-monooxygenase 2.326e-08 0.34
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.476e-08 0.38
PANK1_HUMAN PANK1 Pantothenate kinase 1 2.572e-08 0.29
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 2.583e-08 0.32
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 3.183e-08 0.40
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 3.72e-08 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 3.918e-08 0.34
HSF1_MOUSE Hsf1 Heat shock factor protein 1 4.024e-08 0.41
O61059_LEIME LmGT2 Glucose transporter 4.312e-08 0.41
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 4.521e-08 0.28
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 4.881e-08 0.43
CHS1_CANAX CHS1 Chitin synthase 1 5.69e-08 0.31
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 5.978e-08 0.45
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 6.225e-08 0.39
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 6.419e-08 0.42
Q9BPW0_HUMAN PPP5C Serine/threonine-protein phosphatase 6.736e-08 0.47
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 7.922e-08 0.36
THB_RAT Thrb Thyroid hormone receptor beta 8.065e-08 0.35
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 9.102e-08 0.53
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 9.241e-08 0.38
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.376e-08 0.42
Q43570_TOBAC NtBBF1.1 Zn finger protein 9.481e-08 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.066e-07 0.44
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 1.07e-07 0.32
ALF_MYCTU fba Fructose-bisphosphate aldolase 1.146e-07 0.48
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.162e-07 0.28
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.162e-07 0.28
MYO3A_HUMAN MYO3A Myosin-IIIa 1.162e-07 0.28
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.162e-07 0.28
CBP_HUMAN CREBBP CREB-binding protein 1.174e-07 0.34
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.312e-07 0.30
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.355e-07 0.45
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 1.572e-07 0.31
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.595e-07 0.29
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.615e-07 0.32
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.647e-07 0.43
Q38C41_TRYB2 Phosphotransferase 1.664e-07 0.31
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1.665e-07 0.35
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 1.725e-07 0.47
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.745e-07 0.54
MMP1_HUMAN MMP1 Interstitial collagenase 1.808e-07 0.43
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 1.925e-07 0.35
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.964e-07 0.34
FA7_HUMAN F7 Coagulation factor VII 2.098e-07 0.38
O97467_PLAFA ht1 Hexose transporter 1 2.163e-07 0.41
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 2.269e-07 0.37
DNAB_MYCTU dnaB Replicative DNA helicase 2.283e-07 0.39
REV_HV1H2 rev Protein Rev 2.362e-07 0.29
PAX8_HUMAN PAX8 Paired box protein Pax-8 2.55e-07 0.55
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 2.645e-07 0.28
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 2.645e-07 0.28
MYO3B_HUMAN MYO3B Myosin-IIIb 2.645e-07 0.28
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 2.778e-07 0.56
PA_I34A1 PA Polymerase acidic protein 3.008e-07 0.30
HRH3_HUMAN HRH3 Histamine H3 receptor 3.281e-07 0.43
G5EF15_CAEEL pos-1 Cytoplasmic zinc-finger protein 3.561e-07 0.33
CAH3_HUMAN CA3 Carbonic anhydrase 3 3.621e-07 0.52
Q865E1_MACMU HRH3 Histamine receptor H3 4.187e-07 0.34
Q932Y6_PSEAI bla(tem-2) Beta-lactamase 4.367e-07 0.36
CAH3_BOVIN CA3 Carbonic anhydrase 3 5.217e-07 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 5.298e-07 0.43
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 5.464e-07 0.28
GALR3_HUMAN GALR3 Galanin receptor type 3 5.592e-07 0.39
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 5.944e-07 0.33
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 6.234e-07 0.43
LMP1_EBVB9 LMP1 Latent membrane protein 1 6.488e-07 0.44
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 7.566e-07 0.41
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 8.358e-07 0.29
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 8.358e-07 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 8.752e-07 0.32
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 9.522e-07 0.35
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 9.942e-07 0.33
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1.042e-06 0.28
RARB_HUMAN RARB Retinoic acid receptor beta 1.159e-06 0.33
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 1.229e-06 0.29
THA_HUMAN THRA Thyroid hormone receptor alpha 1.36e-06 0.30
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 1.482e-06 0.29
BXA1_CLOBH botA Botulinum neurotoxin type A 1.504e-06 0.29
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.612e-06 0.54
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.7e-06 0.30
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 1.8e-06 0.40
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 1.858e-06 0.28
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 1.858e-06 0.28
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 1.858e-06 0.28
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 1.858e-06 0.28
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 1.986e-06 0.36
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 2.266e-06 0.43
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 2.31e-06 0.28
AGP1_YEAST AGP1 General amino acid permease AGP1 2.343e-06 0.31
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 2.355e-06 0.31
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 2.355e-06 0.31
CATD_HUMAN CTSD Cathepsin D 2.466e-06 0.36
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.558e-06 0.29
TF_HUMAN F3 Tissue factor 2.778e-06 0.38
PLEC_HUMAN PLEC Plectin 2.799e-06 0.33
MMP13_HUMAN MMP13 Collagenase 3 2.963e-06 0.35
AVR2B_HUMAN ACVR2B Activin receptor type-2B 3.133e-06 0.28
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 3.133e-06 0.28
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 3.133e-06 0.28
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 3.168e-06 0.28
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 3.726e-06 0.38
AA3R_HUMAN ADORA3 Adenosine receptor A3 4.036e-06 0.51
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.057e-06 0.30
CAH_METTE Carbonic anhydrase 4.296e-06 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 4.607e-06 0.30
FFAR1_RAT Ffar1 Free fatty acid receptor 1 4.635e-06 0.31
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 4.685e-06 0.31
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 4.842e-06 0.46
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 5.037e-06 0.28
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 5.037e-06 0.28
GPR35_HUMAN GPR35 G-protein coupled receptor 35 5.163e-06 0.42
FEN1_HUMAN FEN1 Flap endonuclease 1 5.933e-06 0.31
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 6.128e-06 0.32
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 6.512e-06 0.33
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 6.96e-06 0.61
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 7.239e-06 0.44
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 7.77e-06 0.28
INSRR_HUMAN INSRR Insulin receptor-related protein 7.77e-06 0.28
CASP3_HUMAN CASP3 Caspase-3 7.911e-06 0.43
CAH4_BOVIN CA4 Carbonic anhydrase 4 8.144e-06 0.44
Q03732_HBV HBcAg Capsid protein 8.198e-06 0.30
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 8.201e-06 0.38
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 8.717e-06 0.33
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 8.824e-06 0.33
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 9.255e-06 0.37

Nimesulide

PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 3.001e-13 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.602e-10 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 4.945e-06 1.00
PERM_HUMAN MPO Myeloperoxidase 1.322e-05 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 5.814e-05 1.00
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 4.555e-60 0.41
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 1.529e-45 0.36
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 8.564e-41 0.41
UBE2B_HUMAN UBE2B Ubiquitin-conjugating enzyme E2 B 5.953e-37 0.29
NADE_BACAN nadE NH(3)-dependent NAD(+) synthetase 7.62e-36 0.28
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.259e-32 0.34
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 6.149e-30 0.37
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.018e-29 0.40
BRWD1_HUMAN BRWD1 Bromodomain and WD repeat-containing protein 1 3.4e-28 0.35
MYOC_HUMAN MYOC Myocilin 4.494e-28 0.35
BRPF1_HUMAN BRPF1 Peregrin 6.191e-28 0.41
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 2.215e-26 0.43
CP19A_HUMAN CYP19A1 Aromatase 6.519e-26 0.67
PTGES_MOUSE Ptges Prostaglandin E synthase 1.914e-25 0.57
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 6.194e-25 0.37
KMO_RAT Kmo Kynurenine 3-monooxygenase 2.418e-23 0.35
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.377e-23 0.28
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 3.435e-21 0.30
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.856e-21 0.34
COLA_CLOPE colA Collagenase ColA 1.632e-20 0.32
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 1.048e-19 0.31
MGLL_MOUSE Mgll Monoglyceride lipase 1.899e-19 0.32
ERO1A_HUMAN ERO1A ERO1-like protein alpha 1.985e-19 0.31
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 6.787e-19 0.57
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 1.11e-16 0.32
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 2.22e-16 0.41
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.109e-15 0.38
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.288e-14 0.39
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 2.942e-14 0.37
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 3.242e-14 0.32
GCR_HUMAN NR3C1 Glucocorticoid receptor 4.596e-14 0.39
EST1_RABIT Liver carboxylesterase 1 1.494e-13 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.871e-13 0.37
PPOC_ARATH PPOX1 Protoporphyrinogen oxidase 1, chloroplastic 4.4e-13 0.39
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 6.231e-13 0.29
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 8.693e-13 0.32
GCR_RAT Nr3c1 Glucocorticoid receptor 1.457e-12 0.31
BXE_CLOBO botE Botulinum neurotoxin type E 3.63e-12 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.773e-12 0.34
O39930_9HEPC NS5b RNA-directed RNA polymerase 4.424e-12 0.37
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 5.77e-12 0.34
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.215e-11 0.31
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.246e-11 0.32
ACRO_PIG ACR Acrosin 1.466e-11 0.29
I23O2_HUMAN IDO2 Indoleamine 2,3-dioxygenase 2 2.363e-11 0.31
PRGR_HUMAN PGR Progesterone receptor 4.561e-11 0.49
CATL2_HUMAN CTSV Cathepsin L2 5.065e-11 0.40
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 7.17e-11 0.37
PYGL_RAT Pygl Glycogen phosphorylase, liver form 9.976e-11 0.31
CASP4_HUMAN CASP4 Caspase-4 1.585e-10 0.32
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 2.521e-10 0.35
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 1.092e-09 0.40
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.311e-09 0.32
CASP9_HUMAN CASP9 Caspase-9 1.432e-09 0.32
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 1.503e-09 0.33
PGH1_RABIT PTGS1 Prostaglandin G/H synthase 1 1.91e-09 0.30
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 2.491e-09 0.38
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 4.819e-09 0.30
BAZ2A_HUMAN BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 5.62e-09 0.35
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 6.462e-09 0.37
PGH2_RABIT PTGS2 Prostaglandin G/H synthase 2 7.319e-09 0.30
PTR1_LEIMA PTR1 Pteridine reductase 1 9.873e-09 0.31
STXA_SHIDY stxA Shiga toxin subunit A 9.971e-09 0.31
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.402e-08 0.35
C1R_HUMAN C1R Complement C1r subcomponent 1.702e-08 0.29
EST2_HUMAN CES2 Cocaine esterase 2.32e-08 0.33
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 2.983e-08 0.34
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.004e-08 0.30
TF65_HUMAN RELA Transcription factor p65 3.9e-08 0.37
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.239e-08 0.30
CCR2_MOUSE Ccr2 C-C chemokine receptor type 2 6.46e-08 0.32
METC_ECOLI metC Cystathionine beta-lyase MetC 7.847e-08 0.31
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 9.708e-08 0.33
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 1.312e-07 0.37
Q8IL32_PLAF7 Heat shock protein 90, putative 1.456e-07 0.39
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 1.612e-07 0.31
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.709e-07 0.38
PGH1_MOUSE Ptgs1 Prostaglandin G/H synthase 1 1.914e-07 0.57
TYSY_ECOLI thyA Thymidylate synthase 1.929e-07 0.32
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 2.459e-07 0.34
DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 4.339e-07 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.442e-07 0.37
Q6FTL6_CANGA NCE103 Carbonic anhydrase 5.189e-07 0.32
PSBA_SPIOL psbA Photosystem II protein D1 5.645e-07 0.33
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 6.033e-07 0.29
5NTD_RAT Nt5e 5'-nucleotidase 6.081e-07 0.37
TLR4_MOUSE Tlr4 Toll-like receptor 4 8.523e-07 0.32
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.052e-06 0.31
TTHY_HUMAN TTR Transthyretin 1.293e-06 0.31
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.585e-06 0.37
NORA_STAAU norA Quinolone resistance protein NorA 1.715e-06 0.33
MGLL_HUMAN MGLL Monoglyceride lipase 1.992e-06 0.35
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 2.123e-06 0.29
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 2.324e-06 0.30
CAH2_BOVIN CA2 Carbonic anhydrase 2 3.863e-06 0.34
AGP1_YEAST AGP1 General amino acid permease AGP1 4.586e-06 0.30
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.773e-06 0.35
BKRB2_RAT Bdkrb2 B2 bradykinin receptor 4.793e-06 0.31
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 5.372e-06 0.37
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 5.567e-06 0.28
WDR5_HUMAN WDR5 WD repeat-containing protein 5 6.227e-06 0.33
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 6.833e-06 0.30
O49150_SOLTU Lipoxygenase 7.112e-06 0.29
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 8.528e-06 0.36
SKN1_CAEEL skn-1 Protein skinhead-1 8.81e-06 0.31

Zimelidine

SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 2.25e-10 1.00
Q9WTR4_RAT Slc6a2 Transporter 1.478e-08 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.1147 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.2939 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.3896 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 4.324e-91 0.58
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.127e-41 0.45
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.347e-27 0.33
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.156e-20 0.34
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 9.703e-19 0.39
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 3.331e-16 0.37
SQHC_ALIAD shc Squalene--hopene cyclase 4.441e-16 0.31
TA2R_RAT Tbxa2r Thromboxane A2 receptor 2.331e-15 0.45
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 8.854e-13 0.33
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 2.989e-12 0.30
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.712e-12 0.31
CYSP_PLAFA Trophozoite cysteine proteinase 4.054e-11 0.32
LSS_HUMAN LSS Lanosterol synthase 1.382e-10 0.31
CAS1_ARATH CAS1 Cycloartenol synthase 9.644e-09 0.31
ERG7_YEAST ERG7 Lanosterol synthase 9.644e-09 0.31
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 1.76e-06 0.47
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 3.596e-06 0.33
H6TY12_PERAM Nicotinic acetylcholine receptor alpha8 subunit 4.596e-06 0.29

Arachidonic_Acid

CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 5.138e-10 1.00
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 6.68e-10 1.00
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 6.813e-10 1.00
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.031e-07 1.00
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 0.0002947 1.00
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 9.066e-117 0.65
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 4.766e-94 0.89
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 9.125e-91 0.34
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.477e-78 0.42
CNR1_RAT Cnr1 Cannabinoid receptor 1 3.546e-72 0.72
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 6.451e-72 0.45
Q6UB75_PIG Group VII phospholipase A2 2.484e-71 0.41
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 2.939e-69 0.45
LPAR1_MOUSE Lpar1 Lysophosphatidic acid receptor 1 3.001e-69 0.37
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.266e-66 0.49
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 9.1e-61 0.45
A3QR02_CHISP est1 Carboxylic ester hydrolase 1.183e-58 0.37
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 1.965e-57 0.35
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 2.369e-56 0.34
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 2.258e-51 0.63
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 1.351e-50 0.35
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 2.836e-48 0.31
LPAR4_HUMAN LPAR4 Lysophosphatidic acid receptor 4 1.041e-45 0.36
PRP19_YEAST PRP19 Pre-mRNA-processing factor 19 1.176e-45 0.45
LPAR4_MOUSE Lpar4 Lysophosphatidic acid receptor 4 1.634e-45 0.36
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 1.684e-44 0.61
LOXX_SOYBN LOX1.4 Seed linoleate 9S-lipoxygenase 1.968e-44 0.35
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 7.096e-43 0.45
CERT_HUMAN CERT1 Ceramide transfer protein 5.166e-42 0.33
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 5.166e-42 0.33
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 5.166e-42 0.33
LPAR3_RAT Lpar3 Lysophosphatidic acid receptor 3 7.656e-39 0.29
Q95Z89_LEIMA Top1B DNA topoisomerase type IB small subunit 1.381e-38 0.31
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.947e-38 0.30
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 3.391e-38 0.34
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 7.839e-37 0.72
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.054e-36 0.44
MCAT_HUMAN SLC25A20 Mitochondrial carnitine/acylcarnitine carrier protein 1.572e-36 0.29
CP4F2_HUMAN CYP4F2 Cytochrome P450 4F2 3.875e-36 0.29
PA1B2_HUMAN PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 5.971e-36 0.45
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 3.8e-34 0.42
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 3.754e-33 0.60
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 8.789e-33 0.45
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 2.256e-31 0.45
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 3.407e-31 0.44
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 3.519e-31 0.50
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 6.968e-31 0.45
EST1_RABIT Liver carboxylesterase 1 1.69e-29 0.38
LPAR6_HUMAN LPAR6 Lysophosphatidic acid receptor 6 3.125e-29 0.36
POLI_MOUSE Poli DNA polymerase iota 1.52e-28 0.35
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 3.333e-28 0.42
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 8.97e-28 0.45
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 1.668e-27 0.34
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.867e-27 0.45
MGLL_RAT Mgll Monoglyceride lipase 1.079e-26 0.51
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.159e-26 0.42
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 3.415e-26 0.42
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 3.891e-26 0.37
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 5.292e-26 0.45
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.378e-25 0.30
Q9GPG0_MANSE Carboxylic ester hydrolase 1.635e-25 0.31
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.914e-25 0.29
KAT5_HUMAN KAT5 Histone acetyltransferase KAT5 2.258e-25 0.31
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.497e-24 0.89
PA2GA_RABIT PLA2G2A Phospholipase A2, membrane associated 2.158e-24 0.30
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 2.765e-24 0.41
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 9.234e-24 0.60
SPTC2_HUMAN SPTLC2 Serine palmitoyltransferase 2 5.976e-23 0.37
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 8.374e-23 0.42
PA2GC_HUMAN PLA2G2C Putative inactive group IIC secretory phospholipase A2 2.523e-22 0.38
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 5.58e-22 0.36
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 1.018e-21 0.42
EST1_HUMAN CES1 Liver carboxylesterase 1 1.342e-21 0.49
Q9MYX2_PIG CPT1 Carnitine palmitoyl transferase I liver isoform 1.587e-21 0.37
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.741e-20 0.44
DPEP1_PIG DPEP1 Dipeptidase 1 4.945e-20 0.33
EST2_HUMAN CES2 Cocaine esterase 1.48e-19 0.38
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 3.122e-19 0.31
A1ZA98_DROME Jhe Carboxylic ester hydrolase 3.125e-19 0.31
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.094e-18 0.29
POLH_HUMAN POLH DNA polymerase eta 1.982e-18 0.35
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 6.653e-18 0.65
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 9.317e-18 0.44
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.882e-17 0.33
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.335e-17 0.72
KAPCA_RAT Prkaca cAMP-dependent protein kinase catalytic subunit alpha 4.899e-17 0.33
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 1.11e-16 0.50
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 2.22e-16 0.31
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 1.887e-15 0.45
ACPM_HUMAN NDUFAB1 Acyl carrier protein, mitochondrial 7.105e-15 0.28
CIA30_HUMAN NDUFAF1 Complex I intermediate-associated protein 30, mitochondrial 7.105e-15 0.28
NDUA1_HUMAN NDUFA1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 7.105e-15 0.28
NDUA2_HUMAN NDUFA2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 7.105e-15 0.28
NDUA3_HUMAN NDUFA3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 7.105e-15 0.28
NDUA5_HUMAN NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 7.105e-15 0.28
NDUA6_HUMAN NDUFA6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 7.105e-15 0.28
NDUA7_HUMAN NDUFA7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 7.105e-15 0.28
NDUA8_HUMAN NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 7.105e-15 0.28
NDUA9_HUMAN NDUFA9 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 7.105e-15 0.28
NDUAA_HUMAN NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 7.105e-15 0.28
NDUAB_HUMAN NDUFA11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 7.105e-15 0.28
NDUAC_HUMAN NDUFA12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 7.105e-15 0.28
NDUAD_HUMAN NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 7.105e-15 0.28
NDUB1_HUMAN NDUFB1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 7.105e-15 0.28
NDUB2_HUMAN NDUFB2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial 7.105e-15 0.28
NDUB3_HUMAN NDUFB3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 7.105e-15 0.28
NDUB4_HUMAN NDUFB4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 7.105e-15 0.28
NDUB5_HUMAN NDUFB5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial 7.105e-15 0.28
NDUB6_HUMAN NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 7.105e-15 0.28
NDUB7_HUMAN NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 7.105e-15 0.28
NDUB8_HUMAN NDUFB8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 7.105e-15 0.28
NDUB9_HUMAN NDUFB9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 7.105e-15 0.28
NDUBA_HUMAN NDUFB10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 7.105e-15 0.28
NDUBB_HUMAN NDUFB11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 7.105e-15 0.28
NDUC1_HUMAN NDUFC1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial 7.105e-15 0.28
NDUC2_HUMAN NDUFC2 NADH dehydrogenase [ubiquinone] 1 subunit C2 7.105e-15 0.28
NDUF2_HUMAN NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 7.105e-15 0.28
NDUF3_HUMAN NDUFAF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 7.105e-15 0.28
NDUF4_HUMAN NDUFAF4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 7.105e-15 0.28
NDUS1_HUMAN NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 7.105e-15 0.28
NDUS2_HUMAN NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 7.105e-15 0.28
NDUS3_HUMAN NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 7.105e-15 0.28
NDUS4_HUMAN NDUFS4 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 7.105e-15 0.28
NDUS5_HUMAN NDUFS5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 7.105e-15 0.28
NDUS6_HUMAN NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 7.105e-15 0.28
NDUS7_HUMAN NDUFS7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 7.105e-15 0.28
NDUS8_HUMAN NDUFS8 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 7.105e-15 0.28
NDUV1_HUMAN NDUFV1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 7.105e-15 0.28
NDUV2_HUMAN NDUFV2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 7.105e-15 0.28
NDUV3_HUMAN NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 7.105e-15 0.28
NU1M_HUMAN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.105e-15 0.28
NU2M_HUMAN MT-ND2 NADH-ubiquinone oxidoreductase chain 2 7.105e-15 0.28
NU3M_HUMAN MT-ND3 NADH-ubiquinone oxidoreductase chain 3 7.105e-15 0.28
NU4LM_HUMAN MT-ND4L NADH-ubiquinone oxidoreductase chain 4L 7.105e-15 0.28
NU5M_HUMAN MT-ND5 NADH-ubiquinone oxidoreductase chain 5 7.105e-15 0.28
NU6M_HUMAN MT-ND6 NADH-ubiquinone oxidoreductase chain 6 7.105e-15 0.28
NUA4L_HUMAN NDUFA4L2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 7.105e-15 0.28
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.55e-15 0.53
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 1.177e-14 0.72
THAS_HUMAN TBXAS1 Thromboxane-A synthase 2.087e-14 0.41
POLK_HUMAN POLK DNA polymerase kappa 2.598e-14 0.35
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.741e-14 0.56
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 5.296e-14 0.34
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.315e-13 0.42
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 4.889e-13 0.42
Q6RY99_RAT Tetraspanin 9.976e-13 0.34
TLR2_HUMAN TLR2 Toll-like receptor 2 1.227e-12 0.56
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 1.256e-12 0.35
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 6.156e-12 0.45
NDUA4_HUMAN NDUFA4 Cytochrome c oxidase subunit NDUFA4 1.383e-11 0.28
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.425e-11 0.44
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 2.335e-11 0.33
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 6.156e-11 0.50
TA2R_RAT Tbxa2r Thromboxane A2 receptor 8.053e-11 0.38
PI2R_HUMAN PTGIR Prostacyclin receptor 9.459e-11 0.42
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.841e-11 0.56
KPCA_HUMAN PRKCA Protein kinase C alpha type 1.261e-10 0.39
PA2GA_RAT Pla2g2a Phospholipase A2, membrane associated 2.659e-10 0.30
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 5.756e-10 0.61
Q965D6_PLAFA fabG 3-oxoacyl-acyl-carrier protein reductase 9.414e-10 0.31
NU4M_HUMAN MT-ND4 NADH-ubiquinone oxidoreductase chain 4 1.012e-09 0.28
S1PR2_HUMAN S1PR2 Sphingosine 1-phosphate receptor 2 1.044e-09 0.37
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.019e-09 0.41
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 2.214e-09 0.34
CNR2_RAT Cnr2 Cannabinoid receptor 2 5.482e-09 0.63
CNR2_HUMAN CNR2 Cannabinoid receptor 2 8.008e-09 0.61
DYN1_HUMAN DNM1 Dynamin-1 1.323e-08 0.30
KPCA_BOVIN PRKCA Protein kinase C alpha type 2.164e-08 0.39
Q965D7_PLAFA fabZ Beta-hydroxyacyl-ACP dehydratase 3.394e-08 0.31
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 3.549e-08 0.69
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.403e-08 0.33
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 6.162e-08 0.43
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.106e-07 0.30
LEF_BACAN lef Lethal factor 2.108e-07 0.39
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 3.176e-07 0.42
PSBA_SPIOL psbA Photosystem II protein D1 4.304e-07 0.33
TOP1_HUMAN TOP1 DNA topoisomerase 1 4.54e-07 0.81
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 4.707e-07 0.30
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.521e-07 0.31
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 5.716e-07 0.53
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 5.944e-07 0.33
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 6.098e-07 0.68
LPAR1_RAT Lpar1 Lysophosphatidic acid receptor 1 6.257e-07 0.29
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 9.875e-07 0.33
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 1.09e-06 0.30
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.453e-06 0.29
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 1.918e-06 0.53
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.707e-06 0.33
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 5.201e-06 0.33
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 6.415e-06 0.36
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 7.065e-06 0.74
PPCE_RAT Prep Prolyl endopeptidase 8.258e-06 0.33

Cholesterol

RORG_HUMAN RORC Nuclear receptor ROR-gamma 4.318e-08 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.2687 1.00
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.833e-91 0.80
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 1.624e-90 0.77
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.667e-86 0.72
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 1.127e-73 0.40
VDR_RAT Vdr Vitamin D3 receptor 5.409e-72 0.38
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.706e-70 0.59
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.179e-69 0.56
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 3.87e-65 0.39
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.563e-64 0.51
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 6.908e-64 0.80
CP125_MYCTU cyp125 Steroid C26-monooxygenase 8.812e-63 0.79
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.539e-58 0.77
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 1.722e-58 0.52
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.438e-57 0.59
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.243e-55 0.53
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.353e-52 0.57
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 6.519e-51 0.51
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 1.525e-49 0.39
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.716e-49 0.40
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 2.576e-45 0.51
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.448e-45 0.57
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.667e-44 0.61
VDR_PIG VDR Vitamin D3 receptor 1.713e-41 0.33
VTDB_HUMAN GC Vitamin D-binding protein 1.713e-41 0.33
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.882e-41 0.35
VDRA_DANRE vdra Vitamin D3 receptor A 1.879e-40 0.33
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 2.472e-40 0.66
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.634e-36 0.45
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 1.766e-33 0.53
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 8.789e-33 0.41
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 9.217e-33 0.38
CAH4_BOVIN CA4 Carbonic anhydrase 4 5.209e-29 0.38
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.297e-28 0.40
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.824e-27 0.60
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 8.344e-27 0.84
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.728e-26 0.46
VDR_CHICK VDR Vitamin D3 receptor 5.473e-26 0.33
ERG2_YEAST ERG2 C-8 sterol isomerase 1.646e-25 0.42
VDR_HUMAN VDR Vitamin D3 receptor 2.002e-24 0.42
SHBG_RAT Shbg Sex hormone-binding globulin 1.926e-23 0.29
CAS1_ARATH CAS1 Cycloartenol synthase 1.124e-21 0.33
ERG7_YEAST ERG7 Lanosterol synthase 1.124e-21 0.33
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.886e-21 0.57
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 6.75e-21 0.40
NR1H4_HUMAN NR1H4 Bile acid receptor 1.152e-20 0.45
RORA_HUMAN RORA Nuclear receptor ROR-alpha 3.321e-20 0.69
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 1.336e-19 0.71
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.122e-19 0.31
ECR_DROME EcR Ecdysone receptor 7.289e-19 0.35
ESR2_HUMAN ESR2 Estrogen receptor beta 1.113e-18 0.52
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 6.556e-18 0.28
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 7.773e-18 0.28
ANDR_HUMAN AR Androgen receptor 9.669e-18 0.52
ANDR_RAT Ar Androgen receptor 2.884e-17 0.37
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.22e-16 0.80
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.443e-15 0.30
REST_BORBU resT Telomere resolvase ResT 7.105e-15 0.37
ABCBB_HUMAN ABCB11 Bile salt export pump 9.104e-15 0.36
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 9.881e-15 0.31
ERG7_PNECA ERG7 Lanosterol synthase 1.31e-14 0.32
ESR1_HUMAN ESR1 Estrogen receptor 2.38e-13 0.52
SHH_MOUSE Shh Sonic hedgehog protein 2.679e-13 0.63
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 9.012e-13 0.53
CP19A_HUMAN CYP19A1 Aromatase 1.062e-12 0.56
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.707e-12 0.53
B6TK44_MAIZE Cycloeucalenol cycloisomerase 3.999e-12 0.30
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.525e-12 0.53
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.525e-12 0.53
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.589e-11 0.53
Q690N0_BOVIN PGR Progesterone receptor 2.942e-11 0.35
VDR_BOVIN VDR Vitamin D3 receptor 3.177e-11 0.33
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 4.959e-11 0.30
Q2TU57_MAIZE Sterol-8,7-isomerase 4.959e-11 0.30
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 6.457e-11 0.53
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 6.457e-11 0.53
FGF1_HUMAN FGF1 Fibroblast growth factor 1 6.893e-11 0.37
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.883e-11 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.395e-10 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.485e-10 0.53
ANDR_MOUSE Ar Androgen receptor 2.948e-10 0.35
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.855e-10 0.38
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.793e-10 0.57
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 5.881e-10 0.35
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.98e-10 0.53
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.37e-09 0.30
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.559e-09 0.33
GLI1_HUMAN GLI1 Zinc finger protein GLI1 4.926e-09 0.32
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 4.981e-09 0.28
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.633e-09 0.53
DPOLB_RAT Polb DNA polymerase beta 1.197e-08 0.42
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.559e-08 0.35
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 9.412e-08 0.30
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.29e-07 0.74
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 2.056e-07 0.62
SHH_HUMAN SHH Sonic hedgehog protein 3.277e-07 0.32
CEGT_HUMAN UGCG Ceramide glucosyltransferase 4.152e-07 0.62
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 5.312e-07 0.49
HRH3_RAT Hrh3 Histamine H3 receptor 9.155e-07 0.37
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.507e-06 0.30
PRGR_RABIT PGR Progesterone receptor 2.061e-06 0.30
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 3.736e-06 0.47
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.75e-06 0.80
IL2_HUMAN IL2 Interleukin-2 7.451e-06 0.30

Dronedarone

CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.239e-07 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.001203 1.00
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 0.00732 1.00
NMDZ1_MOUSE Grin1 Glutamate receptor ionotropic, NMDA 1 1.51e-42 0.34
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 9.799e-37 0.42
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 3.001e-31 0.30
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 3.442e-28 0.42
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 6.993e-26 0.40
Q66HS9_RAT Slc16a7 Monocarboxylate transporter 2 3.516e-24 0.30
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 3.746e-22 0.31
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.255e-21 0.47
PLM2_PLAFA Plasmepsin-2 3.097e-18 0.41
Q2XUH7_PIG Angiotensin type II receptor 4.802e-18 0.30
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.233e-17 0.37
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 5.551e-15 0.28
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 7.994e-15 0.31
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 5.639e-12 0.32
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.168e-10 0.40
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.258e-10 0.36
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.333e-10 0.36
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 4.321e-10 0.30
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 6.278e-10 0.31
THA_HUMAN THRA Thyroid hormone receptor alpha 1.128e-09 0.47
NPY5R_MOUSE Npy5r Neuropeptide Y receptor type 5 1.324e-09 0.32
AGTR1_PIG AGTR1 Type-1 angiotensin II receptor 3.315e-09 0.28
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 4.585e-09 0.34
LSS_HUMAN LSS Lanosterol synthase 1.306e-08 0.29
SPRE_HUMAN SPR Sepiapterin reductase 1.844e-08 0.32
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.305e-08 0.31
ACES_RAT Ache Acetylcholinesterase 3.656e-08 0.33
Q9JKC1_RAT Bche Carboxylic ester hydrolase 4.389e-08 0.32
THB_HUMAN THRB Thyroid hormone receptor beta 6.738e-08 0.47
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 7.354e-08 0.33
ACES_HUMAN ACHE Acetylcholinesterase 1.275e-07 0.35
MOGT2_HUMAN MOGAT2 2-acylglycerol O-acyltransferase 2 2.562e-07 0.30
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 7.268e-07 0.32
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 9.215e-07 0.30
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 1.11e-06 0.34
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.841e-06 0.28
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.096e-06 0.36
ERG2_YEAST ERG2 C-8 sterol isomerase 2.62e-06 0.47
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 6.605e-06 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.93e-06 0.31

Prenylamine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.248e-07 1.00
NEP_MOUSE Mme Neprilysin 1.085e-77 0.40
NEP_RABIT MME Neprilysin 3.635e-70 0.38
NEP_RAT Mme Neprilysin 4.082e-60 0.36
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 5.002e-56 0.32
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 3.123e-47 0.53
AMPB_RAT Rnpep Aminopeptidase B 5.691e-47 0.36
ACE_MOUSE Ace Angiotensin-converting enzyme 1.581e-45 0.40
NEP_HUMAN MME Neprilysin 5.793e-45 0.36
AMPN_PIG ANPEP Aminopeptidase N 7.611e-41 0.36
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.083e-38 0.36
VM1B1_BOTAS Snake venom metalloproteinase BaP1 1.854e-38 0.32
AMPB_MOUSE Rnpep Aminopeptidase B 6.694e-38 0.30
AMPL_BOVIN LAP3 Cytosol aminopeptidase 6.694e-38 0.30
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.104e-37 0.37
CANX_CHICK Calpain-1 catalytic subunit 1.917e-37 0.30
Q6IE76_BOVIN FDFT1 FDFT1 protein 3.875e-36 0.29
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 9.618e-36 0.40
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 5.141e-35 0.32
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 2.905e-34 0.38
NK1R_RAT Tacr1 Substance-P receptor 3.405e-29 0.38
CBPA1_HUMAN CPA1 Carboxypeptidase A1 3.104e-27 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.729e-26 0.34
AMP1_PLAFQ M1 family aminopeptidase 1.04e-24 0.36
Q3HTL5_PLAFA fp2B Falcipain 2B 4.212e-24 0.30
TYTR_TRYCR TPR Trypanothione reductase 5.263e-24 0.44
AMPB_HUMAN RNPEP Aminopeptidase B 1.139e-23 0.37
Q9NBD4_PLAFA Cysteine protease falcipain-2 1.839e-23 0.29
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.131e-23 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.348e-23 0.66
CALM_BOVIN CALM Calmodulin 2.04e-22 0.62
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.936e-21 0.53
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 6.315e-21 0.33
CPNS1_PIG CAPNS1 Calpain small subunit 1 7.765e-20 0.28
ACE_HUMAN ACE Angiotensin-converting enzyme 4.737e-19 0.38
AMPN_HUMAN ANPEP Aminopeptidase N 4.781e-19 0.37
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 6.741e-19 0.30
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 1.753e-18 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.877e-18 0.30
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 4.879e-18 0.29
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 7.088e-18 0.28
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.11e-16 0.33
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 3.331e-16 0.33
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 4.441e-16 0.30
CATH_HUMAN CTSH Pro-cathepsin H 1.332e-15 0.31
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 4.774e-15 0.36
LY96_HUMAN LY96 Lymphocyte antigen 96 6.106e-15 0.28
MDM4_HUMAN MDM4 Protein Mdm4 7.327e-15 0.37
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 8.438e-15 0.35
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.232e-14 0.62
ACE_RAT Ace Angiotensin-converting enzyme 2.731e-14 0.37
THER_BACTH npr Thermolysin 4.308e-14 0.33
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 8.205e-14 0.31
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.104e-13 0.53
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.965e-13 0.29
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.773e-13 0.41
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 5.299e-13 0.48
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 5.338e-13 0.28
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 9.48e-13 0.31
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.231e-12 0.43
CATL1_BOVIN CTSL Cathepsin L1 1.486e-12 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.795e-12 0.36
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 2.334e-12 0.30
AMPX_VIBPR Bacterial leucyl aminopeptidase 2.757e-12 0.30
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 3.164e-12 0.33
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.272e-12 0.34
O61059_LEIME LmGT2 Glucose transporter 3.651e-12 0.43
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 7.665e-12 0.53
PAPA1_CARPA Papain 8.348e-12 0.30
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 2.063e-11 0.30
AMPN_MOUSE Anpep Aminopeptidase N 3.542e-11 0.30
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 4.364e-11 0.32
Q63380_RAT NET Transporter 4.799e-11 0.35
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.423e-11 0.43
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 5.423e-11 0.33
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 6.148e-11 0.43
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 6.631e-11 0.34
O97467_PLAFA ht1 Hexose transporter 1 1.583e-10 0.43
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.615e-10 0.38
CATB_BOVIN CTSB Cathepsin B 2.166e-10 0.30
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 2.588e-10 0.29
NEP_PIG MME Neprilysin 2.659e-10 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 4.535e-10 0.29
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 7.905e-10 0.29
CALM1_HUMAN CALM1 Calmodulin-1 7.909e-10 0.35
AOC3_HUMAN AOC3 Membrane primary amine oxidase 9.143e-10 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.582e-09 0.30
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.904e-09 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 2.459e-09 0.31
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 2.647e-09 0.53
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.925e-09 0.32
MMP8_RAT Mmp8 Neutrophil collagenase 4.316e-09 0.28
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 6.517e-09 0.66
ANF_HUMAN NPPA Natriuretic peptides A 7.102e-09 0.31
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.139e-08 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.288e-08 0.30
NISCH_HUMAN NISCH Nischarin 1.711e-08 0.32
NISCH_RAT Nisch Nischarin 2.491e-08 0.32
ACE_RABIT ACE Angiotensin-converting enzyme 3.593e-08 0.36
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.014e-08 0.42
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 5.141e-08 0.42
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 6.091e-08 0.33
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 6.978e-08 0.29
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 7.146e-08 0.34
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.188e-07 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.909e-07 0.49
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 2.14e-07 0.40
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.38e-07 0.30
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 3.461e-07 0.31
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 5.533e-07 0.28
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.806e-07 0.41
CATB_HUMAN CTSB Cathepsin B 6.642e-07 0.33
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 7.877e-07 0.33
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 8.97e-07 0.31
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 9.427e-07 0.30
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.051e-06 0.30
Q72874_9HIV1 pol Pol polyprotein 1.149e-06 0.32
ALBU_BOVIN ALB Serum albumin 1.218e-06 0.29
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 1.256e-06 0.31
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 1.317e-06 0.31
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.482e-06 0.29
Q4U254_9ENTO protease Protease 1.966e-06 0.30
BLA2_BACCE blm Metallo-beta-lactamase type 2 2.044e-06 0.32
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 2.088e-06 0.29
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 2.486e-06 0.29
OPRM_RAT Oprm1 Mu-type opioid receptor 2.56e-06 0.36
AA1R_BOVIN ADORA1 Adenosine receptor A1 2.63e-06 0.33
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 2.863e-06 0.34
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.129e-06 0.30
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 4.685e-06 0.31
HRH1_CAVPO HRH1 Histamine H1 receptor 5.231e-06 0.31
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.552e-06 0.30
MMP8_HUMAN MMP8 Neutrophil collagenase 5.761e-06 0.35
CMA1_HUMAN CMA1 Chymase 5.909e-06 0.32
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 7.896e-06 0.29
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 8.32e-06 0.34
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 8.782e-06 0.31

Methapyrilene

HRH1_HUMAN HRH1 Histamine H1 receptor 1.496e-06 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 4.108e-06 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.000124 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.0003123 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.001084 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.003437 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.004184 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.1562 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.3613 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.5633 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.723 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.8044 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.8144 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.8835 1.00
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 1.156e-39 0.47
Q533H1_FELCA UTS2R Urotensin II receptor 3.055e-09 0.29
M2_I72A8 M Matrix protein 2 3.718e-09 0.31
DOPO_BOVIN DBH Dopamine beta-hydroxylase 5.907e-08 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.077e-07 0.29
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 2.253e-07 0.30
CLK3_HUMAN CLK3 Dual specificity protein kinase CLK3 8.946e-06 0.32
HRH1_CAVPO HRH1 Histamine H1 receptor 9.292e-06 0.55

Trioxsalen

AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.001209 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.2317 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.9572 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.969 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.9981 1.00
ANTR2_HUMAN ANTXR2 Anthrax toxin receptor 2 4.884e-19 0.30
CSK21_RAT Csnk2a1 Casein kinase II subunit alpha 8.138e-14 0.34
CSK2B_RAT Csnk2b Casein kinase II subunit beta 8.138e-14 0.34
PPBI_HUMAN ALPI Intestinal-type alkaline phosphatase 6.589e-13 0.36
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 5.401e-11 0.37
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.621e-10 0.36
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 3.522e-08 0.32
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 3.253e-06 0.33

Nebivolol

SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.006199 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9999 1.00
NAC1_HUMAN SLC8A1 Sodium/calcium exchanger 1 5.44e-15 0.32
AK1A1_PIG AKR1A1 Aldo-keto reductase family 1 member A1 1.196e-11 0.28
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 1.54e-09 0.39
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 9.87e-08 0.29

Iproniazid

AOFA_RAT Maoa Amine oxidase [flavin-containing] A 0.04433 1.00
AOFB_RAT Maob Amine oxidase [flavin-containing] B 0.05217 1.00
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 0.3005 1.00
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 0.7342 1.00
SRPK1_MOUSE Srpk1 SRSF protein kinase 1 5.166e-42 0.33
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.213e-29 0.43
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 3.299e-28 0.32
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.563e-25 0.43
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 8.281e-24 0.34
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 2.158e-21 0.43
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 2.491e-21 0.34
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.322e-20 0.34
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 4.173e-17 0.43
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 5.086e-17 0.43
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 1.11e-16 0.43
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 2.22e-16 0.43
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.654e-14 0.37
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 7.279e-13 0.43
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.715e-12 0.32
PANC_MYCTU panC Pantothenate synthetase 5.041e-12 0.31
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 7.527e-11 0.43
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 2.011e-10 0.43
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 2.095e-10 0.29
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 2.768e-10 0.36
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.01e-10 0.43
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.01e-10 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.1e-10 0.33
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 4.211e-10 0.45
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 6.468e-10 0.31
H9B8T9_CAPHI CTSB Cathepsin B 1.113e-09 0.31
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.471e-09 0.36
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.516e-09 0.36
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 2.936e-09 0.36
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.566e-09 0.34
ROCK2_RAT Rock2 Rho-associated protein kinase 2 5.776e-09 0.36
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.3e-09 0.33
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 9e-09 0.36
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 1.322e-08 0.29
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 2.752e-08 0.30
KPCG_HUMAN PRKCG Protein kinase C gamma type 1.141e-07 0.36
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 2.405e-07 0.43
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 2.43e-07 0.31
PEPT1_DERPT DERP1 Peptidase 1 2.493e-07 0.34
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 4.206e-07 0.30
KPCD_HUMAN PRKCD Protein kinase C delta type 5.965e-07 0.43
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 9.396e-07 0.29
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.198e-06 0.28
PRIO_SHEEP PRNP Major prion protein 1.385e-06 0.30
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 2.381e-06 0.43
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 2.844e-06 0.29
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.858e-06 0.33
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 4.402e-06 0.45
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 4.816e-06 0.33
CCL2_HUMAN CCL2 C-C motif chemokine 2 6.45e-06 0.36
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 6.773e-06 0.30
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 8.046e-06 0.35
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 8.86e-06 0.36

Quinestrol

STRP_STRP1 ska Streptokinase A 0.7183 1.00
STS_HUMAN STS Steryl-sulfatase 2.627e-139 0.53
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.274e-59 0.56
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 2.026e-49 0.42
SHBG_HUMAN SHBG Sex hormone-binding globulin 9.418e-48 0.44
Q690N0_BOVIN PGR Progesterone receptor 1.02e-45 0.44
Q95MF8_PIG Sulfotransferase 4.846e-41 0.35
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.518e-33 0.46
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 8.667e-28 0.45
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.727e-25 0.41
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 3.931e-24 0.38
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 1.114e-23 0.29
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 8.154e-22 0.35
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.779e-19 0.41
ESR1_HUMAN ESR1 Estrogen receptor 2.654e-18 0.78
ANDR_RAT Ar Androgen receptor 3.647e-18 0.78
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 2.22e-16 0.41
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 8.882e-16 0.45
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.243e-14 0.43
ESR1_MOUSE Esr1 Estrogen receptor 1.044e-12 0.41
ESR2_MOUSE Esr2 Estrogen receptor beta 1.044e-12 0.41
ESR2_HUMAN ESR2 Estrogen receptor beta 2.185e-12 0.71
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 8.524e-11 0.34
NK1R_RAT Tacr1 Substance-P receptor 4.561e-09 0.35
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.32e-08 0.41
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.58e-08 0.47
ESR1_RAT Esr1 Estrogen receptor 2.268e-08 0.41
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.093e-06 0.41
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 5.066e-06 0.45

Amineptine

SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 0.9111 1.00
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.783e-63 0.38
GSHR_PLAF7 GR3 Glutathione reductase 2.234e-56 0.36
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 4.979e-43 0.34
GLCM_MOUSE Gba Lysosomal acid glucosylceramidase 1.271e-41 0.29
RCOR3_HUMAN RCOR3 REST corepressor 3 2.905e-40 0.32
CERT_HUMAN CERT1 Ceramide transfer protein 1.102e-37 0.30
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 1.469e-37 0.36
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.917e-37 0.30
ACHP_LYMST Acetylcholine-binding protein 8.775e-37 0.35
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 2.703e-34 0.33
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 6.125e-32 0.38
EDNRA_PIG EDNRA Endothelin-1 receptor 1.257e-27 0.32
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.283e-27 0.35
Q8WSF8_APLCA Soluble acetylcholine receptor 5.456e-27 0.33
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 8.612e-25 0.35
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 1.21e-22 0.34
Q7K6A1_PLAF7 Histone deacetylase 4.748e-20 0.32
DRD5_RAT Drd5 D(1B) dopamine receptor 1.026e-19 0.30
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.187e-19 0.40
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 1.487e-18 0.35
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 4.564e-18 0.28
GBRA1_MOUSE Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 9.771e-18 0.28
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.11e-16 0.35
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 5.551e-16 0.36
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 7.772e-16 0.32
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.332e-15 0.34
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 6.994e-15 0.44
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.01e-14 0.38
REST_BORBU resT Telomere resolvase ResT 7.838e-14 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 8.626e-14 0.35
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 9.515e-14 0.33
PRIO_MESAU PRNP Major prion protein 7.645e-13 0.32
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 7.816e-13 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.845e-13 0.37
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 8.944e-13 0.38
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.188e-12 0.37
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.384e-12 0.35
Q6RY99_RAT Tetraspanin 1.465e-12 0.34
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.843e-12 0.29
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 2.763e-12 0.29
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 6.836e-12 0.36
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.023e-11 0.28
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.164e-11 0.35
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 1.236e-11 0.35
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.532e-11 0.38
ITB5_HUMAN ITGB5 Integrin beta-5 1.608e-11 0.33
SNAT_SHEEP AANAT Serotonin N-acetyltransferase 1.068e-10 0.31
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.131e-10 0.37
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 1.413e-10 0.35
Q9SEH8_SOYBN Man1 alpha-1,2-Mannosidase 1.441e-10 0.33
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.002e-10 0.34
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 2.537e-10 0.38
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.571e-10 0.37
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.482e-09 0.33
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.537e-09 0.42
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 1.585e-09 0.34
HDAC9_HUMAN HDAC9 Histone deacetylase 9 3.414e-09 0.35
NEP_RABIT MME Neprilysin 4.189e-09 0.35
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 5.136e-09 0.34
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.494e-09 0.32
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 7.149e-09 0.30
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 8.162e-09 0.28
HDAC1_HUMAN HDAC1 Histone deacetylase 1 9.312e-09 0.35
HRH1_RAT Hrh1 Histamine H1 receptor 1.723e-08 0.36
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.813e-08 0.28
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.264e-08 0.38
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 4.442e-08 0.32
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.565e-08 0.35
HDAC2_HUMAN HDAC2 Histone deacetylase 2 7.082e-08 0.35
V1AR_RAT Avpr1a Vasopressin V1a receptor 7.548e-08 0.31
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 8.525e-08 0.33
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 8.976e-08 0.33
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 9.779e-08 0.36
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.11e-07 0.35
ACES_RAT Ache Acetylcholinesterase 1.417e-07 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.46e-07 0.30
TYTR_TRYCR TPR Trypanothione reductase 1.942e-07 0.34
Q9BEG3_BOVIN 5-lipoxygenase 2.159e-07 0.34
HDAC7_HUMAN HDAC7 Histone deacetylase 7 2.543e-07 0.36
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 3.002e-07 0.28
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 4.161e-07 0.33
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 5.2e-07 0.33
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 5.336e-07 0.36
MTR1B_CHICK Melatonin receptor type 1B 6.322e-07 0.28
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 6.773e-07 0.32
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.046e-06 0.32
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 1.181e-06 0.29
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 2.122e-06 0.31
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.352e-06 0.39
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.74e-06 0.39
PI2R_HUMAN PTGIR Prostacyclin receptor 3.294e-06 0.33
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 3.301e-06 0.33
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.664e-06 0.32
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 4.131e-06 0.35
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 4.188e-06 0.29
HDAC5_HUMAN HDAC5 Histone deacetylase 5 4.397e-06 0.36
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 6.629e-06 0.36
NEP_RAT Mme Neprilysin 8.138e-06 0.45
OPRM_HUMAN OPRM1 Mu-type opioid receptor 8.814e-06 0.38
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 9.257e-06 0.35

Afamelanotide

MC5R_MOUSE Mc5r Melanocortin receptor 5 3.913e-272 0.58
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.105e-216 0.58
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 2.794e-215 0.49
MC3R_MOUSE Mc3r Melanocortin receptor 3 8.94e-205 0.56
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 7.155e-193 0.58
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.389e-174 0.56
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.253e-167 0.52
CD36_RAT Cd36 Platelet glycoprotein 4 1.333e-160 0.52
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.454e-150 0.58
FURIN_HUMAN FURIN Furin 6.413e-149 0.44
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 5.51e-148 0.53
OPRM_RAT Oprm1 Mu-type opioid receptor 3.426e-147 0.54
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.291e-143 0.54
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 1.246e-140 0.49
MC3R_HUMAN MC3R Melanocortin receptor 3 3.086e-128 0.56
NTR1_RAT Ntsr1 Neurotensin receptor type 1 1.834e-122 0.47
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.603e-120 0.53
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 9.075e-116 0.39
OPRD_RAT Oprd1 Delta-type opioid receptor 1.396e-114 0.54
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.692e-110 0.53
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 1.366e-108 0.52
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.108e-107 0.53
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 2.977e-107 0.39
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 2.556e-105 0.39
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 1.151e-104 0.41
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 5.154e-104 0.51
MC4R_HUMAN MC4R Melanocortin receptor 4 1.018e-103 0.56
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 2.546e-100 0.41
KISSR_HUMAN KISS1R KiSS-1 receptor 3.633e-93 0.50
EDNRB_RAT Ednrb Endothelin receptor type B 1.563e-92 0.49
MMP11_MOUSE Mmp11 Stromelysin-3 5.2e-91 0.35
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 5.288e-90 0.37
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 1.361e-89 0.38
RENI_RAT Ren1 Renin 2.181e-88 0.47
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 9.22e-83 0.40
SORT_HUMAN SORT1 Sortilin 1.08e-82 0.46
GRIA1_RAT Gria1 Glutamate receptor 1 3.2e-80 0.33
EDNRA_MOUSE Ednra Endothelin-1 receptor 3.44e-79 0.49
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 2.638e-78 0.37
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 3.401e-78 0.36
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 1.076e-76 0.41
O57585_DANRE oprd1a Opioid receptor homologue 1.076e-76 0.41
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 3.173e-75 0.37
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 3.173e-75 0.37
NK2R_MESAU TACR2 Substance-K receptor 4.813e-75 0.43
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 2.476e-72 0.45
TETX_CLOTE tetX Tetanus toxin 3.111e-72 0.33
POLG_WNV Genome polyprotein 7.14e-72 0.35
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 2.06e-69 0.41
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 5.271e-69 0.51
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 5.541e-69 0.38
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 7.321e-69 0.45
SURA_ECOLI surA Chaperone SurA 7.927e-65 0.52
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 8.621e-64 0.43
GRPR_RAT Grpr Gastrin-releasing peptide receptor 2.76e-63 0.37
NK2R_RAT Tacr2 Substance-K receptor 3.146e-61 0.43
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 5.079e-61 0.51
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 1.051e-60 0.35
CBX7_HUMAN CBX7 Chromobox protein homolog 7 3.03e-59 0.38
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 3.897e-58 0.42
NK1R_CAVPO TACR1 Substance-P receptor 2.124e-57 0.44
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 3.97e-57 0.42
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 3.404e-56 0.45
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 7.48e-56 0.47
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 3.114e-54 0.47
BXA1_CLOBH botA Botulinum neurotoxin type A 2.679e-52 0.34
MBOA4_HUMAN MBOAT4 Ghrelin O-acyltransferase 4.755e-52 0.29
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 4.844e-52 0.57
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 9.818e-52 0.37
TR10A_HUMAN TNFRSF10A Tumor necrosis factor receptor superfamily member 10A 6.87e-50 0.34
EDNRA_PIG EDNRA Endothelin-1 receptor 1.013e-48 0.40
NK1R_RAT Tacr1 Substance-P receptor 1.04e-48 0.51
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 1.161e-48 0.32
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.147e-48 0.41
POLG_DEN26 Genome polyprotein 1.001e-46 0.35
TRY1_BOVIN Cationic trypsin 1.589e-45 0.40
MMP11_HUMAN MMP11 Stromelysin-3 6.103e-45 0.30
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 1.092e-43 0.35
OPRX_MOUSE Oprl1 Nociceptin receptor 1.308e-43 0.33
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 5.999e-43 0.37
HEPS_HUMAN HPN Serine protease hepsin 1.741e-42 0.43
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 5.122e-42 0.36
FSHR_RAT Fshr Follicle-stimulating hormone receptor 6.159e-41 0.51
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 8.165e-41 0.38
PSB6_YEAST PRE7 Proteasome subunit beta type-6 1.918e-40 0.32
CATJ_RAT Ctsj Cathepsin J 2.268e-40 0.36
Q5D7U5_CHICK OXTR Oxytocin-like receptor 1.099e-39 0.31
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.854e-38 0.54
KLK3_HUMAN KLK3 Prostate-specific antigen 1.629e-37 0.33
OPRK_RAT Oprk1 Kappa-type opioid receptor 3.989e-37 0.50
IL1RA_MOUSE Il1rn Interleukin-1 receptor antagonist protein 4.001e-37 0.29
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.123e-37 0.47
Q91H74_9FLAV Genome polyprotein 2.283e-36 0.37
A3EZI9_9HEPC NS3 Genome polyprotein 4.45e-35 0.40
A4HSF7_LEIIN TRYR Trypanothione reductase 9.901e-35 0.43
GRIA1_HUMAN GRIA1 Glutamate receptor 1 7.52e-34 0.33
THRB_HUMAN F2 Prothrombin 1.046e-33 0.40
CATC_RAT Ctsc Dipeptidyl peptidase 1 1.394e-33 0.36
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 7.544e-33 0.38
ELAS_PSEAE lasB Elastase 7.744e-33 0.36
NMBR_RAT Nmbr Neuromedin-B receptor 1.128e-32 0.41
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 1.937e-32 0.43
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.966e-32 0.34
CCKAR_RAT Cckar Cholecystokinin receptor type A 5.186e-32 0.47
NK3R_RAT Tacr3 Neuromedin-K receptor 8.071e-32 0.37
NRP1_RAT Nrp1 Neuropilin-1 1.717e-31 0.49
CFAB_HUMAN CFB Complement factor B 2.257e-31 0.46
EDNRA_HUMAN EDNRA Endothelin-1 receptor 3.052e-31 0.49
AMPN_HUMAN ANPEP Aminopeptidase N 3.573e-30 0.51
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 5.235e-30 0.52
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 5.97e-30 0.46
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 6.835e-30 0.32
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 8.484e-30 0.51
ST14_MOUSE St14 Suppressor of tumorigenicity 14 protein homolog 9.336e-30 0.32
RENI_HUMAN REN Renin 1.042e-29 0.49
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 1.4e-29 0.45
CATZ_RAT Ctsz Cathepsin Z 2.203e-29 0.36
CATE_HUMAN CTSE Cathepsin E 5.799e-29 0.33
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 2.286e-27 0.34
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 5.657e-27 0.32
CTRA_BOVIN Chymotrypsinogen A 3.018e-26 0.34
NK3R_CAVPO TACR3 Neuromedin-K receptor 4.312e-26 0.39
OPRM_HUMAN OPRM1 Mu-type opioid receptor 8.357e-26 0.56
WDR5_HUMAN WDR5 WD repeat-containing protein 5 1.227e-25 0.42
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.431e-25 0.35
NMT_YEAST NMT1 Glycylpeptide N-tetradecanoyltransferase 7.913e-25 0.31
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 8.119e-25 0.40
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 8.445e-25 0.31
NMBR_HUMAN NMBR Neuromedin-B receptor 2.112e-24 0.40
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.007e-24 0.50
Q8I6Z5_PLAF7 Plasmepsin V 5.661e-24 0.32
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 7.178e-24 0.57
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.087e-23 0.29
PAR1_HUMAN F2R Proteinase-activated receptor 1 1.836e-23 0.35
OPRM_MOUSE Oprm1 Mu-type opioid receptor 4.858e-23 0.50
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 6.116e-23 0.28
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 6.219e-23 0.45
IDE_HUMAN IDE Insulin-degrading enzyme 1.935e-22 0.45
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 1.215e-21 0.31
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 4.75e-21 0.34
MMP8_HUMAN MMP8 Neutrophil collagenase 9.403e-21 0.35
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 1.073e-20 0.33
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.795e-20 0.35
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 3.266e-20 0.37
PSB5_YEAST PRE2 Proteasome subunit beta type-5 3.878e-20 0.32
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 5.699e-20 0.44
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 7.22e-20 0.34
TYRO_HUMAN TYR Tyrosinase 3.205e-19 0.34
CTRC_HUMAN CTRC Chymotrypsin-C 3.231e-19 0.38
VM1B1_BOTAS Snake venom metalloproteinase BaP1 3.521e-19 0.30
ACE_HUMAN ACE Angiotensin-converting enzyme 4.935e-19 0.49
PLMN_RAT Plg Plasminogen 8.727e-19 0.38
CATH_RAT Ctsh Pro-cathepsin H 1.721e-18 0.29
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 1.809e-18 0.31
CMA1_HUMAN CMA1 Chymase 2.122e-18 0.38
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 2.272e-18 0.35
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 2.722e-18 0.38
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 5.637e-18 0.28
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 7.032e-18 0.43
UR2R_RAT Uts2r Urotensin-2 receptor 1.276e-17 0.53
PLMN_HUMAN PLG Plasminogen 3.373e-17 0.38
ANPRC_HUMAN NPR3 Atrial natriuretic peptide receptor 3 4.882e-17 0.30
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 5.109e-17 0.56
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.11e-16 0.32
PRSS8_HUMAN PRSS8 Prostasin 1.11e-16 0.34
CATB_RAT Ctsb Cathepsin B 3.331e-16 0.36
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 3.331e-16 0.37
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.441e-16 0.37
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 5.551e-16 0.30
ITB1_HUMAN ITGB1 Integrin beta-1 1.332e-15 0.41
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.22e-15 0.40
CCNA2_HUMAN CCNA2 Cyclin-A2 3.442e-15 0.42
ELNE_HUMAN ELANE Neutrophil elastase 3.886e-15 0.38
OXYR_HUMAN OXTR Oxytocin receptor 6.55e-15 0.34
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 7.772e-15 0.33
ITAV_HUMAN ITGAV Integrin alpha-V 1.021e-14 0.39
CATG_HUMAN CTSG Cathepsin G 2.709e-14 0.33
NK2R_RABIT TACR2 Substance-K receptor 3.73e-14 0.43
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 3.753e-14 0.31
MC5R_HUMAN MC5R Melanocortin receptor 5 4.408e-14 0.56
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 4.863e-14 0.37
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 4.963e-14 0.33
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 6.495e-14 0.41
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 9.692e-14 0.37
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 1.397e-13 0.41
CATL1_HUMAN CTSL Cathepsin L1 3.517e-13 0.41
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 3.944e-13 0.32
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.806e-13 0.31
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.175e-12 0.30
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 1.413e-12 0.36
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.722e-12 0.31
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 2.801e-12 0.32
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 4.308e-12 0.40
V2R_PIG AVPR2 Vasopressin V2 receptor 4.777e-12 0.30
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 5.003e-12 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.606e-12 0.30
NK3R_HUMAN TACR3 Neuromedin-K receptor 7.62e-12 0.37
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.098e-11 0.35
Q72874_9HIV1 pol Pol polyprotein 1.287e-11 0.43
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.629e-11 0.33
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.93e-11 0.46
TAT_HV1H2 tat Protein Tat 1.955e-11 0.34
PRTN3_HUMAN PRTN3 Myeloblastin 2.542e-11 0.34
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 2.718e-11 0.37
TRY3_HUMAN PRSS3 Trypsin-3 3.542e-11 0.30
PRO_HTL1A gag-pro Gag-Pro polyprotein 3.6e-11 0.40
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 3.809e-11 0.34
CASPA_HUMAN CASP10 Caspase-10 4.506e-11 0.32
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 5.275e-11 0.37
MMP2_HUMAN MMP2 72 kDa type IV collagenase 5.278e-11 0.35
PAPA1_CARPA Papain 6.516e-11 0.40
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 8.003e-11 0.37
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.714e-10 0.33
OPRX_HUMAN OPRL1 Nociceptin receptor 2.036e-10 0.45
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 2.187e-10 0.35
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 2.382e-10 0.32
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 2.949e-10 0.29
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.129e-10 0.50
BKRB2_RABIT BDKRB2 B2 bradykinin receptor 4.733e-10 0.29
CBX8_HUMAN CBX8 Chromobox protein homolog 8 6.672e-10 0.29
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 6.991e-10 0.33
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 7.057e-10 0.33
TRY1_HUMAN PRSS1 Trypsin-1 8.023e-10 0.38
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.028e-09 0.33
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.04e-09 0.34
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 1.14e-09 0.35
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.519e-09 0.40
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.609e-09 0.30
D2K2A8_9HEPC NS4A Non-structural protein 4A 2.042e-09 0.38
CASP9_HUMAN CASP9 Caspase-9 3.111e-09 0.32
PPCE_BOVIN PREP Prolyl endopeptidase 3.338e-09 0.29
MEN1_HUMAN MEN1 Menin 3.809e-09 0.60
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 4.356e-09 0.32
THER_BACTH npr Thermolysin 4.574e-09 0.30
TRY1_RAT Prss1 Anionic trypsin-1 5.013e-09 0.32
UPAR_RAT Plaur Urokinase plasminogen activator surface receptor 5.013e-09 0.32
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5.86e-09 0.36
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 6.286e-09 0.38
FA10_BOVIN F10 Coagulation factor X 6.993e-09 0.38
THRB_RAT F2 Prothrombin 7.694e-09 0.32
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 8.422e-09 0.29
EDNRB_PIG EDNRB Endothelin receptor type B 2.328e-08 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 2.793e-08 0.31
V1AR_RAT Avpr1a Vasopressin V1a receptor 2.885e-08 0.34
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 3.169e-08 0.31
NEP_RABIT MME Neprilysin 3.22e-08 0.35
Q82323_9DELA Protease 3.8e-08 0.40
NK2R_HUMAN TACR2 Substance-K receptor 3.948e-08 0.51
CASP1_HUMAN CASP1 Caspase-1 5.084e-08 0.33
PEPA_PIG PGA Pepsin A 7.106e-08 0.37
AMPL_HUMAN LAP3 Cytosol aminopeptidase 8.173e-08 0.31
ITA4_HUMAN ITGA4 Integrin alpha-4 9.007e-08 0.41
ITB3_HUMAN ITGB3 Integrin beta-3 9.242e-08 0.40
V2R_HUMAN AVPR2 Vasopressin V2 receptor 9.308e-08 0.35
ACE_RABIT ACE Angiotensin-converting enzyme 1.155e-07 0.37
Q4U254_9ENTO protease Protease 2.139e-07 0.42
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 4.24e-07 0.30
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.379e-07 0.32
ITB8_HUMAN ITGB8 Integrin beta-8 5.08e-07 0.30
CATD_HUMAN CTSD Cathepsin D 6.253e-07 0.33
NK1R_HUMAN TACR1 Substance-P receptor 6.351e-07 0.53
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 6.957e-07 0.29
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 8.931e-07 0.29
NEP_RAT Mme Neprilysin 1.018e-06 0.37
Q9YQ12_9HIV1 protease Protease 1.062e-06 0.42
CASP5_HUMAN CASP5 Caspase-5 1.435e-06 0.32
FA11_HUMAN F11 Coagulation factor XI 1.53e-06 0.35
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.62e-06 0.42
MMP1_HUMAN MMP1 Interstitial collagenase 1.811e-06 0.35
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 2.32e-06 0.35
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 2.494e-06 0.34
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 2.745e-06 0.30
GRAB_HUMAN GZMB Granzyme B 2.889e-06 0.32
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 3.135e-06 0.31
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 4.42e-06 0.32
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 4.833e-06 0.31
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 9.196e-06 0.37
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 9.302e-06 0.34

Inosine

AA1R_RAT Adora1 Adenosine receptor A1 1.773e-196 0.60
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 3.504e-169 0.45
ADK_TOXGO AK Adenosine kinase 2.561e-152 0.50
ADOK_MYCTO adoK Adenosine kinase 1.559e-151 0.39
AA1R_CHICK ADORA1 Adenosine receptor A1 2.529e-124 0.45
OXGR1_RAT Oxgr1 2-oxoglutarate receptor 1 4.147e-124 0.34
CDD_MOUSE Cda Cytidine deaminase 3.036e-121 0.49
AA2AR_RAT Adora2a Adenosine receptor A2a 1.162e-119 0.50
AA1R_RABIT ADORA1 Adenosine receptor A1 2.139e-112 0.36
DNPH1_HUMAN DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 5.349e-112 0.34
AA3R_RABIT ADORA3 Adenosine receptor A3 1.953e-110 0.36
DNPH1_RAT Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 2.443e-110 0.34
C3SIU2_ECOLX metJ Met repressor 4.338e-104 0.35
CDD_HUMAN CDA Cytidine deaminase 1.156e-98 0.49
AA1R_CAVPO ADORA1 Adenosine receptor A1 5.866e-94 0.60
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 9.893e-93 0.38
AA3R_RAT Adora3 Adenosine receptor A3 1.116e-92 0.50
AA3R_HUMAN ADORA3 Adenosine receptor A3 5.911e-90 0.50
MTAP_MOUSE Mtap S-methyl-5'-thioadenosine phosphorylase 3.76e-80 0.35
AA1R_HUMAN ADORA1 Adenosine receptor A1 1.984e-77 0.50
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 1.066e-73 0.35
P2RY1_RAT P2ry1 P2Y purinoceptor 1 1.427e-71 0.35
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 6.104e-70 0.38
DCAM_HUMAN AMD1 S-adenosylmethionine decarboxylase proenzyme 3.351e-65 0.39
SPEE_HUMAN SRM Spermidine synthase 7.028e-65 0.34
SAHH_HUMAN AHCY Adenosylhomocysteinase 9.351e-65 0.49
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.049e-59 0.45
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 7.907e-59 0.34
Q99MI5_RAT LOC100912604 Spermidine synthase 1.19e-58 0.34
SYQ_HUMAN QARS1 Glutamine--tRNA ligase 1.766e-58 0.35
MBTA_MYCTU mbtA Salicyl-AMP ligase / salicyl-S-ArCP synthetase 4.314e-56 0.38
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.241e-55 0.50
RASK_HUMAN KRAS GTPase KRas 1.327e-55 0.32
ASNS_HUMAN ASNS Asparagine synthetase [glutamine-hydrolyzing] 2.226e-55 0.30
ADK_HUMAN ADK Adenosine kinase 7.218e-55 0.50
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1.742e-52 0.50
HSP7C_HUMAN HSPA8 Heat shock cognate 71 kDa protein 2.656e-52 0.38
KAD3_RAT Ak3 GTP:AMP phosphotransferase AK3, mitochondrial 6.933e-51 0.35
SPSY_HUMAN SMS Spermine synthase 1.07e-49 0.32
PQSA_PSEAE pqsA Anthranilate--CoA ligase 2.423e-48 0.31
KMT5C_HUMAN KMT5C Histone-lysine N-methyltransferase KMT5C 1.274e-47 0.38
SETB1_HUMAN SETDB1 Histone-lysine N-methyltransferase SETDB1 1.274e-47 0.38
IF4E_RABIT EIF4E Eukaryotic translation initiation factor 4E 1.795e-47 0.34
SYRC_HUMAN RARS1 Arginine--tRNA ligase, cytoplasmic 2.434e-47 0.30
G3PC_LEIME GAPC Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2.754e-47 0.31
PYGB_HUMAN PYGB Glycogen phosphorylase, brain form 1.645e-46 0.30
BIP_HUMAN HSPA5 Endoplasmic reticulum chaperone BiP 7.748e-46 0.38
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 4.84e-45 0.32
SYD_ECOLI aspS Aspartate--tRNA ligase 7.877e-45 0.36
MACD1_HUMAN MACROD1 ADP-ribose glycohydrolase MACROD1 1.968e-44 0.35
MACD2_HUMAN MACROD2 ADP-ribose glycohydrolase MACROD2 1.968e-44 0.35
ADA_BOVIN ADA Adenosine deaminase 2.343e-44 0.51
NADK1_LISMF nadK1 NAD kinase 1 3.092e-44 0.35
NADK_STAAC nadK NAD kinase 3.092e-44 0.35
SYS_ECOLI serS Serine--tRNA ligase 9.991e-44 0.35
HSP7C_BOVIN HSPA8 Heat shock cognate 71 kDa protein 3.059e-43 0.34
WALK_STAAU walK Sensor protein kinase WalK 3.059e-43 0.34
HARS1_HUMAN HARS1 Histidine--tRNA ligase, cytoplasmic 4.699e-43 0.34
ENPL_PIG HSP90B1 Endoplasmin 1.204e-42 0.34
P2RY4_RAT P2ry4 P2Y purinoceptor 4 1.726e-42 0.35
MSHC_MYCTU mshC L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 5.166e-42 0.33
ENPP1_RAT Enpp1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.471e-41 0.34
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 6.353e-41 0.35
SETD2_HUMAN SETD2 Histone-lysine N-methyltransferase SETD2 6.678e-41 0.32
A3RLP8_CHV1 UL23 Thymidine kinase 2.055e-40 0.30
METK2_RAT Mat2a S-adenosylmethionine synthase isoform type-2 2.671e-40 0.32
SYY_ECOLI tyrS Tyrosine--tRNA ligase 6.244e-40 0.32
P2RX5_RAT P2rx5 P2X purinoceptor 5 6.706e-40 0.34
P2RX6_RAT P2rx6 P2X purinoceptor 6 6.706e-40 0.34
ADA_MOUSE Ada Adenosine deaminase 2.809e-39 0.49
KAD2_RAT Ak2 Adenylate kinase 2, mitochondrial 3.187e-39 0.35
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.382e-38 0.32
UBA7_HUMAN UBA7 Ubiquitin-like modifier-activating enzyme 7 2.276e-38 0.30
RN5A_HUMAN RNASEL 2-5A-dependent ribonuclease 3.17e-38 0.30
P2RX1_HUMAN P2RX1 P2X purinoceptor 1 3.409e-38 0.35
Q9HWG3_PSEAE pchD Pyochelin biosynthesis protein PchD 9.681e-38 0.30
Q8T6J6_PLAFA ompdc Orotidine 5'-monophosphate decarboxylase 1.627e-37 0.30
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.171e-36 0.34
BIRA_ECOLI birA Bifunctional ligase/repressor BirA 2.43e-36 0.29
Q8TA74_HEMPU Ryanodine receptor 2.71e-36 0.30
IMDH2_MOUSE Impdh2 Inosine-5'-monophosphate dehydrogenase 2 8.267e-35 0.28
Q4VQ11_PIG Adenosine receptor A1 1.172e-34 0.45
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 9.4e-34 0.42
S28A2_HUMAN SLC28A2 Sodium/nucleoside cotransporter 2 2.704e-33 0.30
PARG_BOVIN PARG Poly(ADP-ribose) glycohydrolase 2.51e-32 0.32
ADA_HUMAN ADA Adenosine deaminase 7.391e-31 0.49
P96884_MYCTO birA BirA bifunctional protein 2.685e-30 0.30
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.503e-29 0.35
PUR6_CHICK AIRC Multifunctional protein ADE2 2.297e-27 0.33
TOP1_HUMAN TOP1 DNA topoisomerase 1 3.533e-27 0.33
SYL_ECOLI leuS Leucine--tRNA ligase 5.245e-27 0.33
AMPD1_RABIT AMPD1 AMP deaminase 1 1.343e-26 0.33
KTHY_HUMAN DTYMK Thymidylate kinase 3.612e-26 0.29
KITH_VZVD TK Thymidine kinase 6.259e-26 0.40
NADK_HUMAN NADK NAD kinase 7.184e-26 0.32
ANM7_HUMAN PRMT7 Protein arginine N-methyltransferase 7 1.42e-25 0.32
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 1.524e-25 0.33
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 1.661e-25 0.52
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 3.444e-25 0.34
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 6.244e-25 0.32
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 6.853e-25 0.45
CDK12_HUMAN CDK12 Cyclin-dependent kinase 12 7.913e-25 0.31
UBA6_HUMAN UBA6 Ubiquitin-like modifier-activating enzyme 6 1.087e-24 0.30
RN5A_MOUSE Rnasel 2-5A-dependent ribonuclease 1.342e-24 0.30
PNPH_HUMAN PNP Purine nucleoside phosphorylase 1.74e-24 0.39
AA2AR_CAVPO ADORA2A Adenosine receptor A2a 1.852e-24 0.47
GPR17_HUMAN GPR17 Uracil nucleotide/cysteinyl leukotriene receptor 2.597e-24 0.33
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 4.904e-24 0.30
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 4.904e-24 0.30
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 5.903e-24 0.38
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 1.333e-23 0.31
DHE3_BOVIN GLUD1 Glutamate dehydrogenase 1, mitochondrial 3.915e-23 0.28
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 4.592e-23 0.29
ADCY2_RAT Adcy2 Adenylate cyclase type 2 8.689e-23 0.35
SAHH_MOUSE Ahcy Adenosylhomocysteinase 1.554e-22 0.33
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 5.792e-22 0.32
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 2.303e-21 0.34
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 3.872e-21 0.37
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 4.028e-21 0.44
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 9.983e-21 0.38
BPL1_HUMAN HLCS Biotin--protein ligase 1.451e-20 0.29
SAHH_RAT Ahcy Adenosylhomocysteinase 2.536e-20 0.34
PARG_HUMAN PARG Poly(ADP-ribose) glycohydrolase 4.22e-20 0.32
KITH_HUMAN TK1 Thymidine kinase, cytosolic 4.482e-20 0.38
KITH_RAT Tk1 Thymidine kinase, cytosolic 5.429e-20 0.32
SYI_ECOLI ileS Isoleucine--tRNA ligase 7.563e-20 0.32
MRAY_ECOLI mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.211e-18 0.30
IUNH_CRIFA IUNH Inosine-uridine preferring nucleoside hydrolase 1.406e-18 0.36
O15727_TRYBB Inosine-adenosine-guanosine-nucleoside hydrolase 1.406e-18 0.36
P2RX4_RAT P2rx4 P2X purinoceptor 4 1.474e-18 0.34
METK1_RAT Mat1a S-adenosylmethionine synthase isoform type-1 3.72e-18 0.29
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 6.533e-18 0.30
AA1R_BOVIN ADORA1 Adenosine receptor A1 1.993e-17 0.47
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.172e-17 0.37
PANC_MYCTU panC Pantothenate synthetase 1.11e-16 0.34
B4EH87_BURCJ Lectin 1.443e-15 0.30
DCAM_RAT Amd1 S-adenosylmethionine decarboxylase proenzyme 1.998e-15 0.37
Q9HX69_PSEAE rocR RocR 2.22e-15 0.29
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 2.442e-15 0.49
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2.554e-15 0.34
SAHH2_HUMAN AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 2.665e-15 0.29
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 5.884e-15 0.28
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 6.217e-15 0.37
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 8.105e-15 0.38
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 1.044e-14 0.35
SYMC_HUMAN MARS1 Methionine--tRNA ligase, cytoplasmic 6.062e-14 0.34
P2Y11_HUMAN P2RY11 P2Y purinoceptor 11 6.095e-14 0.34
P2RX1_RAT P2rx1 P2X purinoceptor 1 8.66e-14 0.46
SAHH_PLAF7 Adenosylhomocysteinase 1.549e-13 0.30
P2RY6_RAT P2ry6 P2Y purinoceptor 6 3.164e-13 0.29
A0A0E7NXW5_STAAU birA Bifunctional ligase/repressor BirA 3.333e-13 0.29
TYPH_HUMAN TYMP Thymidine phosphorylase 6.387e-13 0.40
CD69_HUMAN CD69 Early activation antigen CD69 1.562e-12 0.31
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 1.562e-12 0.31
SYTC_HUMAN TARS1 Threonine--tRNA ligase 1, cytoplasmic 2.074e-12 0.32
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 2.816e-12 0.36
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.685e-12 0.43
RAB7A_HUMAN RAB7A Ras-related protein Rab-7a 1.562e-11 0.36
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.033e-11 0.36
CCNK_HUMAN CCNK Cyclin-K 2.276e-11 0.31
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 2.371e-11 0.39
KMT2A_HUMAN KMT2A Histone-lysine N-methyltransferase 2A 1.603e-10 0.38
HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 2.135e-10 0.47
Q8T9Z7_PLAFA PNP Purine nucleoside phosphorylase 2.292e-10 0.30
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 3.132e-10 0.38
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.272e-09 0.38
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.361e-09 0.35
E1BN64_BOVIN PDE3B Phosphodiesterase 9.079e-09 0.29
INMT_HUMAN INMT Indolethylamine N-methyltransferase 1.04e-08 0.38
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 3.82e-08 0.32
I6YFP0_MYCTU birA Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase) 1.408e-07 0.30
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 1.498e-07 0.28
5NTD_RAT Nt5e 5'-nucleotidase 2.736e-07 0.34
IL6_HUMAN IL6 Interleukin-6 2.994e-07 0.28
Q9Y0I0_9TRYP AT1 Adenosine transporter 1 3.35e-07 0.32
5NTD_HUMAN NT5E 5'-nucleotidase 3.876e-07 0.34
IF4E_MOUSE Eif4e Eukaryotic translation initiation factor 4E 5.775e-07 0.30
HS71A_HUMAN HSPA1A Heat shock 70 kDa protein 1A 8.059e-07 0.34
PNPH_BOVIN PNP Purine nucleoside phosphorylase 8.657e-07 0.30
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 1.151e-06 0.39
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.175e-06 0.32
P2Y12_RAT P2ry12 P2Y purinoceptor 12 1.177e-06 0.34
SYT_YERPE thrS Threonine--tRNA ligase 1.435e-06 0.32
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 1.96e-06 0.31
GRK1_HUMAN GRK1 Rhodopsin kinase GRK1 2.524e-06 0.38
ENPL_CANLF HSP90B1 Endoplasmin 2.99e-06 0.34
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 3.512e-06 0.40
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 4.188e-06 0.29
P2RX2_RAT P2rx2 P2X purinoceptor 2 5.334e-06 0.34
AA1R_MOUSE Adora1 Adenosine receptor A1 6.621e-06 0.43
EZH2_HUMAN EZH2 Histone-lysine N-methyltransferase EZH2 7.769e-06 0.38
AMPD3_HUMAN AMPD3 AMP deaminase 3 9.865e-06 0.48

Dantron

Q9BEG3_BOVIN 5-lipoxygenase 3.181e-169 0.57
AL1A7_RAT Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 1.834e-74 0.63
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 3.617e-56 0.40
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 5.384e-43 0.41
SIR2_YEAST SIR2 NAD-dependent histone deacetylase SIR2 1.52e-40 0.32
ALDH2_RAT Aldh2 Aldehyde dehydrogenase, mitochondrial 1.579e-38 0.31
GSHR_PLAF7 GR3 Glutathione reductase 6.435e-38 0.44
TYTR_TRYCR TPR Trypanothione reductase 1.038e-34 0.39
MSRA_BOVIN MSRA Mitochondrial peptide methionine sulfoxide reductase 2.504e-30 0.31
AGRA_STAAU agrA Accessory gene regulator protein A 1.603e-28 0.38
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 3.116e-28 0.50
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.159e-27 0.40
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 4.902e-25 0.63
Q2PCB5_DICLA ca Carbonic anhydrase 1.826e-23 0.36
PGAM1_HUMAN PGAM1 Phosphoglycerate mutase 1 3.395e-23 0.37
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 1.126e-21 0.35
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.218e-20 0.41
DUS1_MOUSE Dusp1 Dual specificity protein phosphatase 1 4.22e-20 0.32
3MG_HUMAN MPG DNA-3-methyladenine glycosylase 7.758e-19 0.36
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 1.158e-17 0.45
REV_HV1H2 rev Protein Rev 1.11e-16 0.40
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.331e-16 0.39
TYSY_ENTFA thyA Thymidylate synthase 3.109e-15 0.29
ITF2_HUMAN TCF4 Transcription factor 4 1.232e-14 0.40
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 1.31e-14 0.36
FIBB_HUMAN FGB Fibrinogen beta chain 5.934e-13 0.35
TERT_HUMAN TERT Telomerase reverse transcriptase 7.457e-13 0.39
DNLI1_HUMAN LIG1 DNA ligase 1 7.834e-13 0.31
RLGM1_TRYBB REL1 RNA-editing ligase 1, mitochondrial 1.108e-12 0.31
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 1.284e-12 0.31
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 2.034e-11 0.33
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.205e-11 0.36
TLR1_MOUSE Tlr1 Toll-like receptor 1 2.743e-11 0.31
TLR2_MOUSE Tlr2 Toll-like receptor 2 2.743e-11 0.31
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 7.066e-11 0.44
ACLY_HUMAN ACLY ATP-citrate synthase 1.414e-10 0.35
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 2.791e-10 0.39
MEP2_YEAST MEP2 Ammonium transporter MEP2 4.084e-10 0.29
P2RX7_MOUSE P2rx7 P2X purinoceptor 7 4.32e-10 0.33
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 1.584e-09 0.54
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 1.705e-09 0.32
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 2.026e-08 0.39
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.165e-08 0.36
TP4A3_HUMAN PTP4A3 Protein tyrosine phosphatase type IVA 3 2.593e-08 0.41
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 4.013e-08 0.39
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 6.44e-08 0.29
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 6.738e-08 0.54
CAH3_BOVIN CA3 Carbonic anhydrase 3 9.381e-08 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 1.243e-07 0.39
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.356e-07 0.31
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.925e-07 0.35
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 2.19e-07 0.38
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 2.648e-07 0.38
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 2.994e-07 0.28
G3P_HUMAN GAPDH Glyceraldehyde-3-phosphate dehydrogenase 3.065e-07 0.46
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 3.298e-07 0.36
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 5.561e-07 0.39
G5EF15_CAEEL pos-1 Cytoplasmic zinc-finger protein 6.747e-07 0.29
ODP2_MYCTU dlaT Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 6.968e-07 0.28
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 1.221e-06 0.54
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.274e-06 0.36
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 2.681e-06 0.55
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 3.477e-06 0.28
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 4.399e-06 0.31
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 5.346e-06 0.36
ELNE_HUMAN ELANE Neutrophil elastase 5.839e-06 0.68
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 6.484e-06 0.35
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 9.557e-06 0.35

Lactose

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 3.027e-147 0.63
LEG4_HUMAN LGALS4 Galectin-4 1.737e-98 0.64
LEG8_HUMAN LGALS8 Galectin-8 1.737e-98 0.64
B4EH87_BURCJ Lectin 1.748e-94 0.63
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 2.742e-86 0.53
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 3.213e-69 0.38
CXB2_HUMAN GJB2 Gap junction beta-2 protein 5.198e-64 0.51
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 1.397e-59 0.34
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 4.263e-57 0.35
CDD_MOUSE Cda Cytidine deaminase 1.353e-53 0.31
FGF1_HUMAN FGF1 Fibroblast growth factor 1 4.69e-52 0.53
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 6.114e-52 0.41
LEG3_HUMAN LGALS3 Galectin-3 2.98e-45 0.64
LUXS_BACSU luxS S-ribosylhomocysteine lyase 1.893e-41 0.32
CDD_HUMAN CDA Cytidine deaminase 3.929e-41 0.31
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 1.52e-40 0.32
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.13e-39 0.36
TYRO_HUMAN TYR Tyrosinase 5.805e-39 0.51
Q77YF8_HV1H2 rev Protein Rev 6.052e-39 0.49
AMY1A_HUMAN AMY1A Alpha-amylase 1 6.231e-39 0.46
P79074_9AGAR cppg1 Endopolygalacturonase 8.333e-36 0.28
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.095e-33 0.53
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 5.386e-32 0.35
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 4.318e-31 0.34
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 2.535e-29 0.29
CD69_HUMAN CD69 Early activation antigen CD69 1.206e-28 0.42
CHIT_YEAST CTS1 Endochitinase 7.288e-28 0.34
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 4.175e-24 0.53
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 4.904e-24 0.30
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 5.204e-24 0.34
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 6.537e-23 0.29
O57585_DANRE oprd1a Opioid receptor homologue 6.537e-23 0.29
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 8.763e-21 0.29
P94451_GEOSE Alpha-amylase 1.04e-20 0.46
GDE_RABIT AGL Glycogen debranching enzyme 3.269e-20 0.45
GLCM_BOVIN GBA Lysosomal acid glucosylceramidase 9.052e-19 0.30
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 1.265e-18 0.30
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 2.576e-18 0.29
IL2_HUMAN IL2 Interleukin-2 5.551e-16 0.31
PDIA1_HUMAN P4HB Protein disulfide-isomerase 6.117e-14 0.35
LEF_BACAN lef Lethal factor 8.527e-14 0.49
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.169e-13 0.29
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.488e-13 0.51
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.195e-13 0.67
ENV_HV1H2 env Envelope glycoprotein gp160 6.108e-13 0.28
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.601e-12 0.67
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 2.614e-12 0.31
OGA_HUMAN OGA Protein O-GlcNAcase 1.293e-11 0.31
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 1.835e-10 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.767e-10 0.45
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 7.625e-10 0.35
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 9.719e-10 0.31
LEG9_HUMAN LGALS9 Galectin-9 1.067e-09 0.44
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.958e-09 0.36
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 5.304e-09 0.34
O96394_LEIAM Arginase 7.319e-09 0.30
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.16e-08 0.67
LYAG_RAT Gaa Lysosomal alpha-glucosidase 1.278e-08 0.46
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.29e-08 0.34
BGAL_HUMAN GLB1 Beta-galactosidase 4.652e-08 0.35
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 4.702e-08 0.43
MAG_HUMAN MAG Myelin-associated glycoprotein 6.174e-08 0.29
LYAG_HUMAN GAA Lysosomal alpha-glucosidase 1.189e-07 0.46
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.662e-07 0.67
AA1R_CHICK ADORA1 Adenosine receptor A1 2.362e-07 0.29
HPSE_HUMAN HPSE Heparanase 2.622e-07 0.53
PPO2_AGABI PPO2 Polyphenol oxidase 2 6.712e-07 0.47
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 1.448e-06 0.31
CHIA_HUMAN CHIA Acidic mammalian chitinase 1.581e-06 0.34
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.989e-06 0.35
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.047e-06 0.35
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 2.061e-06 0.29
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 2.109e-06 0.42
RASH_HUMAN HRAS GTPase HRas 4.349e-06 0.43
CHIB_SERMA chiB Chitinase B 4.971e-06 0.34
IL5_MOUSE Il5 Interleukin-5 8.822e-06 0.30

Benoxaprofen

HPSE_HUMAN HPSE Heparanase 4.312e-140 0.42
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 1.01e-58 0.43
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 3.049e-55 0.40
Q548M1_ECOLX groL 60 kDa chaperonin 3.104e-53 0.39
Q7BGE6_ECOLX groES 10 kDa chaperonin 3.104e-53 0.39
ESR1_MOUSE Esr1 Estrogen receptor 1.103e-51 0.46
ESR2_MOUSE Esr2 Estrogen receptor beta 1.103e-51 0.46
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 8.594e-50 0.49
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.351e-39 0.39
FAS_MOUSE Fasn Fatty acid synthase 4.067e-39 0.31
Q7TNH1_MESAU ppara Peroxisome proliferator-activated receptor alpha 1.007e-38 0.31
DUS26_HUMAN DUSP26 Dual specificity protein phosphatase 26 7.101e-36 0.28
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 4.096e-35 0.45
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 1.516e-30 0.37
CETP_HUMAN CETP Cholesteryl ester transfer protein 2.759e-29 0.48
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 5.245e-27 0.33
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.742e-26 0.38
OX1R_MOUSE Hcrtr1 Orexin receptor type 1 2.847e-23 0.29
OX2R_MOUSE Hcrtr2 Orexin receptor type 2 2.847e-23 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.422e-21 0.39
FFAR2_HUMAN FFAR2 Free fatty acid receptor 2 1.509e-19 0.46
ESR2_RAT Esr2 Estrogen receptor beta 1.515e-19 0.46
KLK14_HUMAN KLK14 Kallikrein-14 6.785e-18 0.28
ESR1_RAT Esr1 Estrogen receptor 1.117e-17 0.46
GP119_HUMAN GPR119 Glucose-dependent insulinotropic receptor 5.42e-17 0.39
KMO_HUMAN KMO Kynurenine 3-monooxygenase 3.331e-16 0.33
HELD_ECOLI helD DNA helicase IV 2.665e-15 0.29
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 6.883e-15 0.33
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 5.362e-14 0.35
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.473e-13 0.38
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 4.515e-13 0.35
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.401e-12 0.45
ESR2_HUMAN ESR2 Estrogen receptor beta 2.151e-12 0.46
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.707e-12 0.39
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 1.508e-11 0.28
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 2.328e-11 0.29
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 3.836e-11 0.33
Q7ZJM1_9HIV1 pol Integrase 6.088e-11 0.41
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 6.813e-11 0.31
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 6.835e-11 0.33
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 9.814e-11 0.36
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.497e-10 0.59
SYPC_CANAX PRS Proline--tRNA ligase, cytoplasmic 2.404e-10 0.32
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 2.997e-10 0.31
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 4.21e-10 0.35
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 5.368e-10 0.31
IL8_HUMAN CXCL8 Interleukin-8 6.464e-10 0.33
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 1.554e-09 0.36
ESR1_HUMAN ESR1 Estrogen receptor 3.55e-09 0.46
CTRC_HUMAN CTRC Chymotrypsin-C 4.577e-09 0.35
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 5.148e-09 0.30
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 6.603e-09 0.30
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 1.699e-08 0.29
LIPS_RAT Lipe Hormone-sensitive lipase 2.011e-08 0.38
DGAT1_RAT Dgat1 Diacylglycerol O-acyltransferase 1 2.244e-08 0.38
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 3.051e-08 0.47
AMPC_ECOLI ampC Beta-lactamase 4.333e-08 0.35
TSPO_RAT Tspo Translocator protein 4.364e-08 0.33
PTGES_HUMAN PTGES Prostaglandin E synthase 5.105e-08 0.34
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 5.28e-08 0.37
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 6.605e-08 0.30
ADA_HUMAN ADA Adenosine deaminase 9.685e-08 0.35
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 1.631e-07 0.34
ALBU_BOVIN ALB Serum albumin 2.534e-07 0.33
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 2.698e-07 0.34
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 4.194e-07 0.39
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 4.617e-07 0.33
SKN1_CAEEL skn-1 Protein skinhead-1 5.51e-07 0.45
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 9.444e-07 0.32
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 1.4e-06 0.31
POL_HV1BR gag-pol Gag-Pol polyprotein 1.535e-06 0.29
PPARA_RAT Ppara Peroxisome proliferator-activated receptor alpha 2.198e-06 0.31
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.483e-06 0.29
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 2.789e-06 0.29
KLK5_HUMAN KLK5 Kallikrein-5 3.168e-06 0.28
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.306e-06 0.31
SENP6_HUMAN SENP6 Sentrin-specific protease 6 3.891e-06 0.55
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 4.084e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.188e-06 0.29
MMP13_BOVIN MMP13 Collagenase 3 6.191e-06 0.33
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 6.347e-06 0.29
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 7.583e-06 0.32

Ospemifene

ERR3_HUMAN ESRRG Estrogen-related receptor gamma 8.095e-139 0.65
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.662e-119 0.54
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 4.765e-58 0.54
SAT1_HUMAN SAT1 Diamine acetyltransferase 1 4.673e-41 0.33
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 9.105e-40 0.50
ACRO_PIG ACR Acrosin 1.985e-34 0.39
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.821e-30 0.43
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 2.828e-30 0.35
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 2.391e-26 0.32
ESR1_HUMAN ESR1 Estrogen receptor 1.181e-25 0.70
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 3.625e-23 0.36
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.747e-20 0.43
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.278e-19 0.50
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 6.661e-16 0.50
ERG2_YEAST ERG2 C-8 sterol isomerase 3.886e-15 0.43
KLK_PIG Glandular kallikrein 1.754e-14 0.29
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.209e-14 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.179e-13 0.36
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 4.551e-12 0.38
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.71e-12 0.32
S100B_HUMAN S100B Protein S100-B 4.111e-11 0.33
CP19A_HUMAN CYP19A1 Aromatase 1.303e-10 0.70
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.433e-10 0.33
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 4.084e-10 0.29
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 5.162e-10 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 1.67e-08 0.70
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.816e-07 0.33
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.015e-06 0.34
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 4.331e-06 0.30
LSS_HUMAN LSS Lanosterol synthase 7.309e-06 0.34
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 9.664e-06 0.33

Debrisoquine

MEP50_HUMAN WDR77 Methylosome protein 50 1.567e-133 0.40
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 3.454e-132 0.40
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.081e-55 0.44
DRD4_RAT Drd4 D(4) dopamine receptor 1.046e-42 0.42
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.708e-41 0.39
ENV_MMTVG env Envelope glycoprotein gp70 1.142e-39 0.31
ENV_VILV env Envelope glycoprotein gp160 1.176e-38 0.31
A8PUY1_MALGO LIP1, secretory lipase (Family 3) 3.56e-37 0.29
GAG_AVIER gag Gag polyprotein 5.593e-34 0.31
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 2.743e-30 0.53
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 5.22e-27 0.45
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 6.957e-27 0.42
O31048_PORGN DPP IV Dipeptidyl peptidase IV 8.671e-25 0.38
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.82e-24 0.45
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 3.782e-24 0.56
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 9.074e-24 0.38
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 5.943e-21 0.47
Q6PRC7_IXORI Legumain-like protease 7.077e-19 0.35
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 1.858e-18 0.29
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 7.935e-18 0.39
M2_I72A8 M Matrix protein 2 1.719e-17 0.31
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.331e-16 0.39
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 7.772e-16 0.29
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.331e-15 0.39
RYR2_HUMAN RYR2 Ryanodine receptor 2 3.22e-15 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 6.883e-15 0.43
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.454e-14 0.33
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 9.504e-14 0.30
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 3.3e-13 0.36
PPCE_HUMAN PREP Prolyl endopeptidase 7.742e-13 0.34
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 2.334e-12 0.30
TRPC6_HUMAN TRPC6 Short transient receptor potential channel 6 3.021e-12 0.36
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.032e-12 0.42
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 7.677e-12 0.40
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 2.232e-11 0.39
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.488e-11 0.42
TRPC3_HUMAN TRPC3 Short transient receptor potential channel 3 4.393e-11 0.36
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.361e-10 0.38
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.27e-10 0.42
Q89535_HRSV F Fusion glycoprotein F0 5.437e-10 0.32
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.029e-09 0.33
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.077e-09 0.38
LIPS_HUMAN LIPE Hormone-sensitive lipase 5.383e-09 0.36
DPP9_HUMAN DPP9 Dipeptidyl peptidase 9 6.167e-08 0.38
FA10_HUMAN F10 Coagulation factor X 8.224e-08 0.46
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.059e-07 0.39
BAD_HUMAN BAD Bcl2-associated agonist of cell death 1.623e-07 0.31
AMP1_PLAFQ M1 family aminopeptidase 1.728e-07 0.43
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.305e-07 0.37
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.9e-07 0.40
SEPR_HUMAN FAP Prolyl endopeptidase FAP 4.26e-07 0.33
TNFA_HUMAN TNF Tumor necrosis factor 5.532e-07 0.33
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 7.935e-07 0.48
EED_HUMAN EED Polycomb protein EED 1.054e-06 0.39
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.764e-06 0.30
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.117e-06 0.42
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.552e-06 0.30
LIPE_MOUSE Lipg Endothelial lipase 5.571e-06 0.40
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 6.316e-06 0.29
ENPL_CANLF HSP90B1 Endoplasmin 6.365e-06 0.32
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 9.349e-06 0.29
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 9.453e-06 0.42

Didecyldimethylammonium

PLB1_CRYNB PLB1 Phospholipase B 4.622e-122 0.65
SC6A8_RAT Slc6a8 Sodium- and chloride-dependent creatine transporter 1 1.656e-118 0.75
DYN1_HUMAN DNM1 Dynamin-1 3.002e-80 0.94
ADH7_HUMAN ADH7 All-trans-retinol dehydrogenase [NAD(+)] ADH7 2.281e-40 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 7.596e-35 0.59
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 1.809e-33 0.33
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 3.451e-30 0.33
ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 4.497e-30 0.44
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 4.497e-30 0.44
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 9.052e-27 0.44
Q9GPG0_MANSE Carboxylic ester hydrolase 2.847e-23 0.29
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.142e-22 0.59
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 2.29e-22 0.50
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 6.051e-20 0.32
PHLC_BACCE plc Phospholipase C 1.225e-19 0.30
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 9.283e-19 0.44
A1ZA98_DROME Jhe Carboxylic ester hydrolase 1.485e-17 0.29
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.441e-17 0.65
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 4.441e-15 0.29
EST1_RABIT Liver carboxylesterase 1 1.854e-14 0.35
EST2_HUMAN CES2 Cocaine esterase 1.119e-11 0.35
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 2.583e-10 0.32
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 3.547e-10 0.32
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 5.64e-10 0.32
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 8.421e-10 0.59
EST1_HUMAN CES1 Liver carboxylesterase 1 2.087e-09 0.35
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 3.507e-09 0.70
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 4.503e-09 0.78
Q8IL32_PLAF7 Heat shock protein 90, putative 1.027e-07 0.78
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.214e-07 0.37
LPAR2_HUMAN LPAR2 Lysophosphatidic acid receptor 2 4.023e-07 0.32
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.875e-07 0.33
MGLL_MOUSE Mgll Monoglyceride lipase 2.258e-06 0.32
ADH1A_HUMAN ADH1A Alcohol dehydrogenase 1A 2.686e-06 0.32
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.849e-06 0.31
STE24_YEAST STE24 CAAX prenyl protease 1 5.352e-06 0.35
PA21B_HUMAN PLA2G1B Phospholipase A2 7.023e-06 0.70

Benzoic_acid

EST1_RABIT Liver carboxylesterase 1 5.582e-115 0.82
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 4.414e-82 0.59
EST2_HUMAN CES2 Cocaine esterase 4.562e-78 0.82
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 4.766e-72 0.42
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 4.416e-66 0.59
Q2PCB5_DICLA ca Carbonic anhydrase 7.874e-65 0.58
Q44079_AERHY cphA2 Beta-lactamase 1.045e-63 0.42
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 5.839e-63 0.42
USP_DROME usp Protein ultraspiracle 3.168e-61 0.41
MANR_PSEPU mdlA Mandelate racemase 7.191e-58 0.32
CBPA3_HUMAN CPA3 Mast cell carboxypeptidase A 1.158e-55 0.31
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 1.283e-55 0.43
RXRG_MOUSE Rxrg Retinoic acid receptor RXR-gamma 8.586e-55 0.33
RXRB_MOUSE Rxrb Retinoic acid receptor RXR-beta 1.171e-53 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 1.29e-53 0.82
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 2.671e-53 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 6.072e-53 0.38
ECR_DROME EcR Ecdysone receptor 4.297e-50 0.41
AL1A1_RAT Aldh1a1 Retinal dehydrogenase 1 2.048e-49 0.33
HIF1N_HUMAN HIF1AN Hypoxia-inducible factor 1-alpha inhibitor 2.433e-48 0.38
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 4.728e-48 0.39
CYC_HUMAN CYCS Cytochrome c 3.737e-47 0.38
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 5.965e-45 0.36
BLA2_BACCE blm Metallo-beta-lactamase type 2 5.086e-44 0.39
RARB_HUMAN RARB Retinoic acid receptor beta 1.285e-43 0.41
G3V906_RAT Hcar1 Hydroxycarboxylic acid receptor 1 1.353e-43 0.35
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 4.229e-42 0.48
D3ZDM7_RAT Ddo D-aspartate oxidase 5.166e-42 0.33
OXDD_MOUSE Ddo D-aspartate oxidase 5.166e-42 0.33
RAGE_RAT Ager Advanced glycosylation end product-specific receptor 5.166e-42 0.33
ECR_BOMMO EcR Ecdysone receptor 1.479e-41 0.41
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 4.101e-41 0.38
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.177e-40 0.44
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.153e-39 0.46
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.383e-37 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.865e-37 0.78
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 3.56e-37 0.29
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.725e-37 0.36
RARG_HUMAN RARG Retinoic acid receptor gamma 1.81e-36 0.41
RCOR3_HUMAN RCOR3 REST corepressor 3 1.377e-35 0.28
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.233e-35 0.35
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 6.767e-35 0.48
BLAB_BACCE Metallo-beta-lactamase type 2 1.521e-34 0.39
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 9.333e-34 0.41
BLAB_SERMA Metallo-beta-lactamase type 2 6e-33 0.41
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 3.098e-32 0.40
DYN2_RAT Dnm2 Dynamin-2 1.125e-31 0.39
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.381e-31 0.48
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 1.441e-30 0.42
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 9.154e-30 0.39
RXRA_HUMAN RXRA Retinoic acid receptor RXR-alpha 1.926e-29 0.36
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 4.128e-29 0.42
RXRB_HUMAN RXRB Retinoic acid receptor RXR-beta 4.652e-29 0.33
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 1.079e-28 0.35
E3UJZ5_SPOLI Ecdysone receptor 2.466e-28 0.41
RARA_HUMAN RARA Retinoic acid receptor alpha 3.215e-28 0.38
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.692e-28 0.42
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 5.96e-27 0.38
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 6.423e-27 0.48
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 7.722e-27 0.48
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 7.864e-27 0.55
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.315e-26 0.48
MEP1B_HUMAN MEP1B Meprin A subunit beta 2.162e-26 0.33
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 7.017e-26 0.38
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 7.517e-26 0.33
Q43014_PRUAV Beta-glucosidase 1.635e-25 0.31
EPHB_MYCTO Epoxide hydrolase B 1.839e-25 0.41
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.164e-25 0.34
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.704e-25 0.38
O87171_SPHPI lsdA Dioxygenase 3.332e-25 0.31
PA_I34A1 PA Polymerase acidic protein 1.387e-24 0.46
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.723e-24 0.41
LUCI_AQULA Luciferin 4-monooxygenase 1.997e-24 0.34
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 6.916e-24 0.42
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 7.581e-24 0.40
PA_I000X PA Polymerase acidic protein 1.103e-23 0.46
HMGB1_HUMAN HMGB1 High mobility group protein B1 6.377e-23 0.28
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.836e-22 0.36
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.287e-22 0.38
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.354e-21 0.29
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 1.571e-21 0.34
IL8_HUMAN CXCL8 Interleukin-8 2.244e-21 0.35
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 3.707e-21 0.32
RXRG_HUMAN RXRG Retinoic acid receptor RXR-gamma 5.989e-21 0.33
CATG_HUMAN CTSG Cathepsin G 6.542e-21 0.38
OXDD_HUMAN DDO D-aspartate oxidase 6.654e-21 0.33
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 1.631e-20 0.38
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.088e-20 0.32
LUCI_PHOPY Luciferin 4-monooxygenase 1.149e-19 0.38
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.295e-19 0.34
UREA_CANEN Urease 1.558e-18 0.33
HSF1_MOUSE Hsf1 Heat shock factor protein 1 1.574e-18 0.41
CAH3_HUMAN CA3 Carbonic anhydrase 3 1.632e-18 0.58
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 1.893e-18 0.41
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 2.893e-18 0.33
HDAC8_HUMAN HDAC8 Histone deacetylase 8 4.889e-18 0.37
Q7K6A1_PLAF7 Histone deacetylase 9.056e-18 0.28
KMO_RAT Kmo Kynurenine 3-monooxygenase 1.221e-17 0.31
AGP1_YEAST AGP1 General amino acid permease AGP1 1.616e-17 0.31
DOPO_HUMAN DBH Dopamine beta-hydroxylase 1.983e-17 0.38
EST5_RAT Liver carboxylesterase B-1 2.142e-17 0.31
FEN1_HUMAN FEN1 Flap endonuclease 1 2.445e-17 0.35
MITF_HUMAN MITF Microphthalmia-associated transcription factor 3.646e-17 0.38
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.11e-16 0.57
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.11e-16 0.41
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 2.22e-16 0.35
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 2.22e-16 0.33
TTHY_HUMAN TTR Transthyretin 2.22e-16 0.40
SENP7_HUMAN SENP7 Sentrin-specific protease 7 3.331e-16 0.41
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 6.661e-16 0.31
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.11e-15 0.46
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 1.221e-15 0.34
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1.554e-15 0.38
AHK3_ARATH AHK3 Histidine kinase 3 1.665e-15 0.29
HES1_MOUSE Hes1 Transcription factor HES-1 1.665e-15 0.29
SENP6_HUMAN SENP6 Sentrin-specific protease 6 1.887e-15 0.39
REST_BORBU resT Telomere resolvase ResT 1.998e-15 0.38
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.998e-15 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 6.661e-15 0.37
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 7.438e-15 0.28
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.549e-15 0.46
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 8.993e-15 0.39
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.077e-14 0.32
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 1.321e-14 0.31
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.41e-14 0.38
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.032e-14 0.58
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 2.065e-14 0.38
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 2.187e-14 0.31
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.309e-14 0.58
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.953e-14 0.41
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.308e-14 0.42
KC1A_PIG CSNK1A1 Casein kinase I isoform alpha 4.097e-14 0.31
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 4.341e-14 0.39
CAH12_HUMAN CA12 Carbonic anhydrase 12 5.695e-14 0.58
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 6.051e-14 0.35
ACES_ANOGA Ace Acetylcholinesterase 9.27e-14 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.18e-13 0.30
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 1.719e-13 0.30
HCAR2_RAT Hcar2 Hydroxycarboxylic acid receptor 2 2.437e-13 0.31
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 2.482e-13 0.29
P89582_9HIV2 pol Integrase 2.482e-13 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 3.313e-13 0.58
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 3.536e-13 0.30
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.81e-13 0.48
RARB_MOUSE Rarb Retinoic acid receptor beta 4.252e-13 0.31
ACES_TETCF ache Acetylcholinesterase 5.15e-13 0.41
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 5.851e-13 0.38
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.289e-13 0.58
PRIO_SHEEP PRNP Major prion protein 7.152e-13 0.32
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 7.399e-13 0.33
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 8.933e-13 0.32
EST1_PIG Liver carboxylesterase 1.078e-12 0.69
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 1.586e-12 0.41
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 1.658e-12 0.37
BXE_CLOBO botE Botulinum neurotoxin type E 1.69e-12 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.026e-12 0.42
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 2.203e-12 0.34
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 2.391e-12 0.30
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 2.594e-12 0.40
NR1H4_HUMAN NR1H4 Bile acid receptor 3.305e-12 0.42
AHK4_ARATH AHK4 Histidine kinase 4 4.628e-12 0.29
AROA_ECOLI aroA 3-phosphoshikimate 1-carboxyvinyltransferase 4.908e-12 0.37
Q7ZJM1_9HIV1 pol Integrase 5.137e-12 0.38
POLG_CXB3N Genome polyprotein 5.9e-12 0.33
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 6.095e-12 0.38
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 7.075e-12 0.31
OXDA_HUMAN DAO D-amino-acid oxidase 7.154e-12 0.43
CAH2_HUMAN CA2 Carbonic anhydrase 2 8.167e-12 0.58
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 9.7e-12 0.29
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 9.789e-12 0.42
RARA_MOUSE Rara Retinoic acid receptor alpha 1.073e-11 0.31
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.092e-11 0.34
SENP8_HUMAN SENP8 Sentrin-specific protease 8 1.205e-11 0.39
DNLI1_HUMAN LIG1 DNA ligase 1 1.437e-11 0.28
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.498e-11 0.39
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.789e-11 0.58
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.848e-11 0.58
FACE2_HUMAN RCE1 CAAX prenyl protease 2 2.605e-11 0.33
Q9NBA7_PLAFA Cysteine protease falcipain-3 2.783e-11 0.30
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 3.213e-11 0.39
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 3.369e-11 0.35
MAP1_ECOLI map Methionine aminopeptidase 3.394e-11 0.33
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 4.112e-11 0.58
H9B8T9_CAPHI CTSB Cathepsin B 5.029e-11 0.40
BLAB_AERHY cphA Metallo-beta-lactamase type 2 6.059e-11 0.35
Q9UM81_HUMAN PTPsigma PTPsigma-(Brain) 6.343e-11 0.29
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 6.501e-11 0.44
VACHT_TETCF Vesicular acetylcholine transporter 8.498e-11 0.35
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.068e-10 0.31
HDAC7_HUMAN HDAC7 Histone deacetylase 7 1.074e-10 0.37
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.084e-10 0.43
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.124e-10 0.58
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.345e-10 0.35
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.381e-10 0.37
DNAB_MYCTU dnaB Replicative DNA helicase 2.005e-10 0.39
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 2.151e-10 0.58
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.252e-10 0.58
Q8IL32_PLAF7 Heat shock protein 90, putative 2.367e-10 0.39
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.966e-10 0.41
PPCE_PIG PREP Prolyl endopeptidase 3.168e-10 0.34
RNH1_HUMAN RNASEH1 Ribonuclease H1 3.238e-10 0.30
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.287e-10 0.37
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.579e-10 0.32
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 4.834e-10 0.40
Q6DMN0_TOXGO CPL Cathepsin L 5.732e-10 0.29
Q8WSF8_APLCA Soluble acetylcholine receptor 5.759e-10 0.33
RECA_MYCTU recA Protein RecA 5.894e-10 0.39
AOX_TRYBB AOX Alternative oxidase, mitochondrial 8.149e-10 0.31
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 1.07e-09 0.38
ACES_MOUSE Ache Acetylcholinesterase 1.399e-09 0.34
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.543e-09 0.36
OXDA_PIG DAO D-amino-acid oxidase 1.557e-09 0.38
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 1.645e-09 0.30
CTRA_BOVIN Chymotrypsinogen A 1.725e-09 0.34
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 1.761e-09 0.41
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 1.803e-09 0.31
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.15e-09 0.35
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 2.163e-09 0.39
PPAP_HUMAN ACP3 Prostatic acid phosphatase 2.391e-09 0.35
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 2.432e-09 0.38
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.603e-09 0.41
HDAC5_HUMAN HDAC5 Histone deacetylase 5 2.721e-09 0.37
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 2.888e-09 0.38
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 3.766e-09 0.34
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 3.861e-09 0.34
CAH4_HUMAN CA4 Carbonic anhydrase 4 6.079e-09 0.58
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 6.284e-09 0.50
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 7.286e-09 0.31
R1AB_SARS rep Replicase polyprotein 1ab 8.363e-09 0.30
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 9.972e-09 0.36
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.043e-08 0.29
VE1_HPV11 E1 Replication protein E1 1.056e-08 0.30
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.081e-08 0.34
APEX1_HUMAN APEX1 DNA-(apurinic or apyrimidinic site) lyase 1.121e-08 0.31
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 1.136e-08 0.30
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.171e-08 0.48
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 1.247e-08 0.30
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 1.322e-08 0.29
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 1.335e-08 0.40
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.396e-08 0.31
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.406e-08 0.29
ACHP_LYMST Acetylcholine-binding protein 1.813e-08 0.33
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.932e-08 0.35
Q8WMX0_BOVIN Muscarinic receptor M1 2.143e-08 0.28
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 2.176e-08 0.41
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.254e-08 0.28
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.291e-08 0.39
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.757e-08 0.42
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 3.101e-08 0.39
CAH3_BOVIN CA3 Carbonic anhydrase 3 3.632e-08 0.35
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.301e-08 0.33
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.192e-08 0.28
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5.257e-08 0.33
ACMSD_HUMAN ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 5.975e-08 0.30
Q9BEG3_BOVIN 5-lipoxygenase 6.371e-08 0.34
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 6.603e-08 0.34
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 6.713e-08 0.33
CMA1_HUMAN CMA1 Chymase 7.433e-08 0.38
LUCI_PHOPE Luciferin 4-monooxygenase 7.654e-08 0.31
LOX5_MOUSE Alox5 Arachidonate 5-lipoxygenase 8.316e-08 0.35
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 8.656e-08 0.31
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.226e-07 0.44
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 1.385e-07 0.39
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.4e-07 0.36
PA2GD_HUMAN PLA2G2D Group IID secretory phospholipase A2 1.508e-07 0.32
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.61e-07 0.29
HDAC9_HUMAN HDAC9 Histone deacetylase 9 1.801e-07 0.35
RHOA_HUMAN RHOA Transforming protein RhoA 2.088e-07 0.43
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 2.341e-07 0.39
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.362e-07 0.29
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.542e-07 0.40
NR4A2_HUMAN NR4A2 Nuclear receptor subfamily 4 group A member 2 2.729e-07 0.30
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.869e-07 0.28
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 3.063e-07 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 3.409e-07 0.33
UCHL1_HUMAN UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 3.447e-07 0.29
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 3.51e-07 0.34
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 4.014e-07 0.32
Q5TU56_ANOGA 1272966 Carbonic anhydrase 4.236e-07 0.46
G5EF15_CAEEL pos-1 Cytoplasmic zinc-finger protein 4.371e-07 0.32
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 4.445e-07 0.38
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 5.536e-07 0.35
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 5.738e-07 0.32
RARG_MOUSE Rarg Retinoic acid receptor gamma 5.904e-07 0.28
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 5.921e-07 0.35
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 6.253e-07 0.34
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 6.636e-07 0.40
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 6.663e-07 0.46
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 7.271e-07 0.30
RET4_HUMAN RBP4 Retinol-binding protein 4 7.555e-07 0.37
MPIP2_HUMAN CDC25B M-phase inducer phosphatase 2 8.857e-07 0.41
Q8MWR1_SPOFR USP Ultraspiracle protein 1.074e-06 0.34
Q8MWR2_SPOFR EcR Ecdysteroid receptor 1.074e-06 0.34
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.149e-06 0.31
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 1.166e-06 0.35
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 1.324e-06 0.28
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.383e-06 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.45e-06 0.42
TCMO_POPKI CYP73A16 Trans-cinnamate 4-monooxygenase 1.467e-06 0.36
C0IX24_STYPI CA2 Carbonic anhydrase 1.499e-06 0.46
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.499e-06 0.46
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.647e-06 0.38
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 1.653e-06 0.31
B2LUN4_PIG GSK3-beta Glycogen synthase kinase 3 beta 1.788e-06 0.31
NEUR3_HUMAN NEU3 Sialidase-3 1.959e-06 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.972e-06 0.44
Q8ST54_TRYCR HK Phosphotransferase 2.07e-06 0.28
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.129e-06 0.44
PLEC_HUMAN PLEC Plectin 2.537e-06 0.32
B2V8E3_SULSY Carbonate dehydratase 2.571e-06 0.46
B5SU02_STYPI CA Alpha carbonic anhydrase 2.571e-06 0.46
Q31FD6_HYDCU Carbonic anhydrase, alpha family 2.571e-06 0.46
PA21B_HUMAN PLA2G1B Phospholipase A2 2.633e-06 0.36
NR1H4_MOUSE Nr1h4 Bile acid receptor 2.794e-06 0.30
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 2.849e-06 0.29
TYRO_HUMAN TYR Tyrosinase 3.023e-06 0.58
ELNE_HUMAN ELANE Neutrophil elastase 4.247e-06 0.40
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 4.447e-06 0.38
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 4.894e-06 0.42
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 4.945e-06 0.33
DPOL_VACCW POL DNA polymerase 5.02e-06 0.29
A6YCJ1_9METZ Astrosclerin-3 5.277e-06 0.46
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 5.387e-06 0.38
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 5.473e-06 0.44
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 5.753e-06 0.38
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 5.882e-06 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 6.174e-06 0.34
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 7.693e-06 0.32
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 7.824e-06 0.44
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 7.842e-06 0.30
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 7.938e-06 0.41
ACES_RAT Ache Acetylcholinesterase 8.233e-06 0.32
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 8.279e-06 0.28
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 8.279e-06 0.28
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 8.639e-06 0.32
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 9.165e-06 0.44
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 9.906e-06 0.37
Q6FTL6_CANGA NCE103 Carbonic anhydrase 9.911e-06 0.46

Methaqualone

HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 6.952e-113 0.54
I23O2_HUMAN IDO2 Indoleamine 2,3-dioxygenase 2 1.177e-76 0.55
HCAR1_HUMAN HCAR1 Hydroxycarboxylic acid receptor 1 6.608e-51 0.46
ATP4A_PIG ATP4A Potassium-transporting ATPase alpha chain 1 6.089e-40 0.43
BGLR_HUMAN GUSB Beta-glucuronidase 2.896e-39 0.33
VDAC2_HUMAN VDAC2 Voltage-dependent anion-selective channel protein 2 4.536e-38 0.30
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 1.336e-36 0.43
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 4.008e-32 0.40
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 4.186e-31 0.39
SC6A9_RAT Slc6a9 Sodium- and chloride-dependent glycine transporter 1 8.956e-30 0.43
C1R_HUMAN C1R Complement C1r subcomponent 4.433e-29 0.31
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 2.881e-27 0.38
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 5.245e-27 0.33
DYR_BOVIN DHFR Dihydrofolate reductase 2.243e-26 0.33
SUMO1_HUMAN SUMO1 Small ubiquitin-related modifier 1 5.245e-24 0.30
SHH_MOUSE Shh Sonic hedgehog protein 1.048e-23 0.33
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.479e-22 0.33
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 1.205e-20 0.41
GLUP_BACSU gluP Rhomboid protease GluP 1.193e-19 0.31
RAD1_HUMAN RAD1 Cell cycle checkpoint protein RAD1 1.913e-19 0.31
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 3.368e-18 0.31
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 4.617e-18 0.32
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5.109e-17 0.38
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.11e-16 0.32
JUN_HUMAN JUN Transcription factor AP-1 1.11e-16 0.56
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5.551e-16 0.38
SCAF_HHV11 UL26 Capsid scaffolding protein 1.332e-15 0.31
HRH3_HUMAN HRH3 Histamine H3 receptor 1.543e-14 0.46
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 7.361e-14 0.40
A3KMY8_BOVIN GUSB Beta-glucuronidase 5.181e-13 0.31
Q38C41_TRYB2 Phosphotransferase 5.983e-12 0.35
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 7.263e-12 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 9.779e-12 0.36
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.548e-11 0.31
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 3.644e-11 0.37
PRIO_HUMAN PRNP Major prion protein 1.584e-10 0.34
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 2.005e-10 0.34
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 3.539e-10 0.44
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 4.887e-10 0.47
MPI_HUMAN MPI Mannose-6-phosphate isomerase 8.284e-10 0.35
PERM_HUMAN MPO Myeloperoxidase 8.713e-10 0.38
MTSI_SPISQ sssIM CPG DNA methylase 3.598e-09 0.29
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 3.648e-09 0.31
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 7.842e-09 0.34
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 9.506e-09 0.41
PA21B_HUMAN PLA2G1B Phospholipase A2 1.07e-08 0.41
HRH3_MOUSE Hrh3 Histamine H3 receptor 1.256e-08 0.33
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 1.469e-08 0.45
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.846e-08 0.40
1433G_HUMAN YWHAG 14-3-3 protein gamma 3.548e-08 0.29
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 4.651e-08 0.36
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 4.823e-08 0.33
LOXL3_HUMAN LOXL3 Lysyl oxidase homolog 3 5.363e-08 0.28
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 6.462e-08 0.42
ALKB3_HUMAN ALKBH3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 9.558e-08 0.30
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 1.028e-07 0.30
MK11_MOUSE Mapk11 Mitogen-activated protein kinase 11 1.038e-07 0.29
PDE7A_HUMAN PDE7A High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 1.157e-07 0.48
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 1.403e-07 0.33
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 1.714e-07 0.37
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 1.87e-07 0.30
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.073e-07 0.36
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.924e-07 0.56
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 3.048e-07 0.39
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 3.629e-07 0.29
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 4.986e-07 0.35
CASR_HUMAN CASR Extracellular calcium-sensing receptor 6.953e-07 0.38
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.102e-06 0.41
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 1.159e-06 0.31
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.385e-06 0.30
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 2.698e-06 0.31
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 2.932e-06 0.55
LUCI_AQULA Luciferin 4-monooxygenase 3.933e-06 0.30
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 4.002e-06 0.32
GCN5_YEAST GCN5 Histone acetyltransferase GCN5 4.296e-06 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.414e-06 0.30
THER_BACTH npr Thermolysin 5.179e-06 0.44
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 5.606e-06 0.44
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 8.642e-06 0.32

Carbocisteine

BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 9.188e-110 0.61
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.719e-97 0.48
GLN1B_ECOLI glnA Glutamine synthetase 3.044e-72 0.34
LUXS_BACSU luxS S-ribosylhomocysteine lyase 1.752e-69 0.37
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 5.324e-63 0.32
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 1.202e-58 0.39
DHAS_HELPY asd Aspartate-semialdehyde dehydrogenase 3.604e-58 0.46
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 1.955e-57 0.46
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 1.215e-56 0.39
GSH1_HUMAN GCLC Glutamate--cysteine ligase catalytic subunit 1.432e-53 0.30
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 1.887e-52 0.41
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 6.114e-52 0.41
BHMT2_HUMAN BHMT2 S-methylmethionine--homocysteine S-methyltransferase BHMT2 1.721e-49 0.39
ARGI1_HUMAN ARG1 Arginase-1 3.418e-49 0.32
LUXS_ECOLI luxS S-ribosylhomocysteine lyase 2.422e-46 0.37
LUXS_VIBCB luxS S-ribosylhomocysteine lyase 2.422e-46 0.37
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 6.251e-42 0.39
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 4.803e-41 0.34
ARGI2_HUMAN ARG2 Arginase-2, mitochondrial 8.37e-41 0.32
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 3.136e-38 0.41
KYNU_HUMAN KYNU Kynureninase 6.122e-38 0.30
GRIA1_HUMAN GRIA1 Glutamate receptor 1 7.628e-37 0.32
CBPM_HUMAN CPM Carboxypeptidase M 1.097e-35 0.28
OTC_HUMAN OTC Ornithine carbamoyltransferase, mitochondrial 1.097e-35 0.28
TY3H_RAT Th Tyrosine 3-monooxygenase 1.097e-35 0.28
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.107e-35 0.29
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 2.527e-35 0.39
GRIA1_MOUSE Gria1 Glutamate receptor 1 8.661e-35 0.28
GRIA4_HUMAN GRIA4 Glutamate receptor 4 2.361e-31 0.33
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.348e-30 0.38
GRIA2_RAT Gria2 Glutamate receptor 2 3.979e-29 0.31
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 2.5e-28 0.41
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 2.859e-27 0.39
ARGI1_RAT Arg1 Arginase-1 3.081e-26 0.32
GRIA3_RAT Gria3 Glutamate receptor 3 4.826e-25 0.29
GRIA4_RAT Gria4 Glutamate receptor 4 1.738e-24 0.29
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 1.139e-23 0.38
STE14_YEAST STE14 Protein-S-isoprenylcysteine O-methyltransferase 1.444e-23 0.29
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 5.518e-23 0.28
GRIA2_HUMAN GRIA2 Glutamate receptor 2 9.041e-21 0.32
GRIA3_HUMAN GRIA3 Glutamate receptor 3 7.642e-19 0.29
GSTM1_HUMAN GSTM1 Glutathione S-transferase Mu 1 1.523e-18 0.29
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 4.879e-18 0.29
GRPE_ECOLI grpE Protein GrpE 6.785e-18 0.28
TY3H_HUMAN TH Tyrosine 3-monooxygenase 8.104e-18 0.28
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 1.332e-15 0.30
NOS2_RAT Nos2 Nitric oxide synthase, inducible 2.298e-14 0.31
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.356e-13 0.32
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 1.582e-13 0.39
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 2.282e-13 0.30
MVD1_HUMAN MVD Diphosphomevalonate decarboxylase 3.497e-12 0.30
GRIA1_RAT Gria1 Glutamate receptor 1 1.523e-11 0.29
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 4.82e-11 0.41
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 1.422e-10 0.45
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 2.263e-10 0.35
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 5.037e-10 0.34
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.477e-09 0.31
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.241e-08 0.32
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 4.945e-08 0.31
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 6.44e-08 0.29
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 1.099e-07 0.41
DCOR_RAT Odc1 Ornithine decarboxylase 1.849e-07 0.29
CBPB1_PIG CPB1 Carboxypeptidase B 4.055e-07 0.29
NOS1_MOUSE Nos1 Nitric oxide synthase, brain 4.4e-06 0.30
DPEP1_PIG DPEP1 Dipeptidase 1 8.468e-06 0.31
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 8.558e-06 0.28

Ribostamycin

Q77YF8_HV1H2 rev Protein Rev 5.49e-109 0.88
CXB2_HUMAN GJB2 Gap junction beta-2 protein 1.272e-88 0.71
LEG4_HUMAN LGALS4 Galectin-4 8.654e-66 0.38
LEG8_HUMAN LGALS8 Galectin-8 8.654e-66 0.38
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 6.462e-39 0.38
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.003e-38 0.37
GGTA1_PIG GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 2.222e-36 0.29
B4EH87_BURCJ Lectin 2.754e-36 0.38
Q70E71_9ENTE aac(6')-Ii Aminoglycoside N(6')-acetyltransferase 2.173e-35 0.34
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 1.601e-23 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.811e-23 0.37
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 9.993e-23 0.36
TAT_HV112 tat Protein Tat 6.971e-22 0.38
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.645e-20 0.77
TYRO_HUMAN TYR Tyrosinase 1.065e-18 0.32
LEF_BACAN lef Lethal factor 8.737e-18 0.88
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 3.922e-17 0.37
AMY1A_HUMAN AMY1A Alpha-amylase 1 1.665e-15 0.29
LEG3_HUMAN LGALS3 Galectin-3 2.109e-15 0.38
GDE_RABIT AGL Glycogen debranching enzyme 1.21e-14 0.32
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 9.381e-14 0.77
P94451_GEOSE Alpha-amylase 1.704e-13 0.29
CD69_HUMAN CD69 Early activation antigen CD69 3.63e-12 0.30
LEG9_HUMAN LGALS9 Galectin-9 7.091e-07 0.30
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.452e-06 0.33
LYAG_RAT Gaa Lysosomal alpha-glucosidase 5.148e-06 0.32

Oxeladin

AMYP_RAT Amy2 Pancreatic alpha-amylase 3.253e-104 0.61
Q8WMX0_BOVIN Muscarinic receptor M1 1.052e-49 0.61
CBX2_HUMAN CBX2 Chromobox protein homolog 2 1.71e-35 0.28
CBX6_HUMAN CBX6 Chromobox protein homolog 6 1.71e-35 0.28
CDY1_HUMAN CDY1; CDY1B Testis-specific chromodomain protein Y 1 1.71e-35 0.28
CDYL_HUMAN CDYL Chromodomain Y-like protein 1.71e-35 0.28
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.218e-26 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 4.616e-24 0.35
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 8.254e-20 0.31
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.025e-19 0.61
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.551e-16 0.64
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 9.215e-15 0.32
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 7.883e-14 0.30
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.35e-13 0.32
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.548e-13 0.64
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.844e-12 0.52
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.895e-12 0.61
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.02e-11 0.36
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.045e-10 0.64
CBX8_HUMAN CBX8 Chromobox protein homolog 8 1.104e-09 0.28
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 3.363e-09 0.28
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 1.536e-08 0.28
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.909e-08 0.57
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.056e-07 0.32
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 2.495e-07 0.33
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 3.065e-07 0.28
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 7.949e-07 0.30
CBX7_HUMAN CBX7 Chromobox protein homolog 7 2.415e-06 0.28
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 2.5e-06 0.35
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.532e-06 0.42
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.903e-06 0.57

Ximelagatran

TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 7.699e-99 0.40
MLX_HUMAN MLX Max-like protein X 5.99e-75 0.46
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 3.561e-65 0.34
THRB_HUMAN F2 Prothrombin 2.818e-64 0.53
LGMN_HUMAN LGMN Legumain 1.167e-49 0.33
BIRC7_HUMAN BIRC7 Baculoviral IAP repeat-containing protein 7 5.966e-39 0.31
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.521e-34 0.34
PROC_HUMAN PROC Vitamin K-dependent protein C 9.084e-34 0.37
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.066e-32 0.34
TRY1_BOVIN Cationic trypsin 1.633e-31 0.53
F1SH20_PIG TRHDE Uncharacterized protein 9.529e-31 0.29
VHL_HUMAN VHL von Hippel-Lindau disease tumor suppressor 3.173e-30 0.31
ELOB_HUMAN ELOB Elongin-B 8.947e-28 0.29
ELOC_HUMAN ELOC Elongin-C 8.947e-28 0.29
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 1.448e-27 0.41
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 2.468e-25 0.32
TF_HUMAN F3 Tissue factor 2.586e-23 0.34
FA7_HUMAN F7 Coagulation factor VII 2.832e-23 0.39
TMPS2_HUMAN TMPRSS2 Transmembrane protease serine 2 5.704e-22 0.35
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 6.236e-18 0.29
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 1.196e-17 0.29
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.504e-17 0.46
A3EZI9_9HEPC NS3 Genome polyprotein 1.665e-15 0.35
PLMN_HUMAN PLG Plasminogen 3.941e-14 0.38
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 2.388e-12 0.29
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 2.52e-12 0.29
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 1.312e-11 0.49
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 1.55e-11 0.29
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.011e-11 0.34
IL2_HUMAN IL2 Interleukin-2 2.916e-10 0.28
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 3.443e-10 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 1.402e-09 0.33
LGMN_MOUSE Lgmn Legumain 5.727e-09 0.37
TRY1_HUMAN PRSS1 Trypsin-1 6.96e-09 0.38
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 7.664e-09 0.31
ELNE_HUMAN ELANE Neutrophil elastase 7.984e-09 0.33
IL2RA_MOUSE Il2ra Interleukin-2 receptor subunit alpha 4.728e-08 0.28
FA10_HUMAN F10 Coagulation factor X 9.932e-08 0.53
DEF_STRPN def Peptide deformylase 2.268e-07 0.31
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 3.048e-07 0.42
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 4.514e-07 0.29
DEF_STAAU def Peptide deformylase 7.352e-07 0.31
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 3.253e-06 0.32
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 4.283e-06 0.29

Citric_acid

S13A5_HUMAN SLC13A5 Solute carrier family 13 member 5 1.152e-96 0.44
ACLY_RAT Acly ATP-citrate synthase 2.265e-80 0.46
S13A2_HUMAN SLC13A2 Solute carrier family 13 member 2 5.13e-43 0.34
S13A3_HUMAN SLC13A3 Solute carrier family 13 member 3 5.13e-43 0.34
S13A5_MOUSE Slc13a5 Solute carrier family 13 member 5 5.13e-43 0.34
S13A5_RAT Slc13a5 Solute carrier family 13 member 5 5.13e-43 0.34
EAA3_RAT Slc1a1 Excitatory amino acid transporter 3 8.37e-41 0.32
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 1.947e-38 0.30
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.947e-38 0.30
ACLY_HUMAN ACLY ATP-citrate synthase 1.77e-29 0.46
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 8.933e-22 0.35
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 5.551e-16 0.30
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.804e-12 0.37
Q6RY99_RAT Tetraspanin 8.327e-12 0.32
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 1.936e-10 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.91e-07 0.30
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 7.045e-07 0.29
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.87e-06 0.33
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 2.064e-06 0.30
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 2.561e-06 0.31
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 3.285e-06 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.703e-06 0.37

Picric_acid

COMT_RAT Comt Catechol O-methyltransferase 8.832e-87 0.79
COMT_PIG COMT Catechol O-methyltransferase 3.399e-74 0.48
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 1.868e-71 0.50
Q8X6S1_ECO57 nfsA Nitroreductase A 1.907e-53 0.42
COMT_MOUSE Comt Catechol O-methyltransferase 1.917e-37 0.30
NTRK1_RAT Ntrk1 High affinity nerve growth factor receptor 7.142e-37 0.29
PMM2_HUMAN PMM2 Phosphomannomutase 2 9.064e-35 0.39
VCAM1_HUMAN VCAM1 Vascular cell adhesion protein 1 3.285e-32 0.41
Q9XQA6_POAAN psbA Photosystem II protein D1 1.542e-29 0.58
FAS_RAT Fasn Fatty acid synthase 1.837e-29 0.32
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 3.693e-26 0.32
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 1.373e-24 0.45
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 1.937e-24 0.36
PHOP1_HUMAN PHOSPHO1 Phosphoethanolamine/phosphocholine phosphatase 3.872e-24 0.39
MANBA_HUMAN MANBA Beta-mannosidase 6.243e-24 0.29
MYOC_HUMAN MYOC Myocilin 1.444e-23 0.29
GPR35_HUMAN GPR35 G-protein coupled receptor 35 8.238e-22 0.73
EST1_RABIT Liver carboxylesterase 1 2.282e-19 0.42
Q01HZ7_ORYSA OSIGBa0132E09-OSIGBa0108L24.11 Glutamine synthetase 6.741e-19 0.30
RLGM1_TRYBB REL1 RNA-editing ligase 1, mitochondrial 3.381e-18 0.45
HIS1_MYCTU hisG ATP phosphoribosyltransferase 1.805e-17 0.39
MGLL_HUMAN MGLL Monoglyceride lipase 1.11e-16 0.36
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 3.331e-16 0.32
KTHY_HUMAN DTYMK Thymidylate kinase 3.442e-15 0.33
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.865e-14 0.65
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.143e-14 0.34
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 6.761e-14 0.34
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 1.781e-13 0.37
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 2.173e-13 0.29
TTHY_HUMAN TTR Transthyretin 4.873e-13 0.79
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 1.036e-12 0.31
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 1.141e-12 0.41
PNMT_BOVIN PNMT Phenylethanolamine N-methyltransferase 4.011e-12 0.31
COMT_HUMAN COMT Catechol O-methyltransferase 1.989e-11 0.39
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3.002e-11 0.45
PNMT_HUMAN PNMT Phenylethanolamine N-methyltransferase 4.753e-11 0.31
CAH2_BOVIN CA2 Carbonic anhydrase 2 6.809e-11 0.32
Q8IL32_PLAF7 Heat shock protein 90, putative 4.357e-10 0.43
KMO_RAT Kmo Kynurenine 3-monooxygenase 4.832e-10 0.31
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 5.425e-10 0.40
EST2_HUMAN CES2 Cocaine esterase 1.479e-09 0.42
GRIK5_RAT Grik5 Glutamate receptor ionotropic, kainate 5 1.645e-09 0.30
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.885e-09 0.30
COLA_CLOPE colA Collagenase ColA 2.394e-09 0.32
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 2.944e-09 0.31
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 2.944e-09 0.31
MPI_HUMAN MPI Mannose-6-phosphate isomerase 8.091e-09 0.39
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.075e-08 0.33
METC_ECOLI metC Cystathionine beta-lyase MetC 1.18e-08 0.34
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.241e-08 0.32
OXDA_PIG DAO D-amino-acid oxidase 1.432e-08 0.31
RECA_MYCTU recA Protein RecA 2.325e-08 0.44
PTR1_LEIMA PTR1 Pteridine reductase 1 3.186e-08 0.28
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.792e-08 0.30
DNAB_MYCTU dnaB Replicative DNA helicase 4.408e-08 0.44
MITF_HUMAN MITF Microphthalmia-associated transcription factor 3.978e-07 0.41
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 4.707e-07 0.30
EST1_HUMAN CES1 Liver carboxylesterase 1 6.907e-07 0.39
Q8ST54_TRYCR HK Phosphotransferase 8.676e-07 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 9.84e-07 0.35
PSBA_SPIOL psbA Photosystem II protein D1 1.125e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.312e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 5.327e-06 0.29
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 6.014e-06 0.30

Carboxin

KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 9.617e-83 0.36
LIPL_RAT Lpl Lipoprotein lipase 1.995e-45 0.32
RCOR3_HUMAN RCOR3 REST corepressor 3 1.225e-37 0.30
PRIO_SHEEP PRNP Major prion protein 5.796e-37 0.34
Q25615_ONCVO Chitinase 8.062e-32 0.34
EPHB_MYCTO Epoxide hydrolase B 1.296e-23 0.38
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.743e-21 0.36
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 1.133e-20 0.34
ANO1_HUMAN ANO1 Anoctamin-1 3.875e-20 0.33
Q7K6A1_PLAF7 Histone deacetylase 9.052e-19 0.30
AHK3_ARATH AHK3 Histidine kinase 3 4.441e-16 0.31
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 9.137e-14 0.38
BXE_CLOBO botE Botulinum neurotoxin type E 1.463e-13 0.33
TAT_HV112 tat Protein Tat 8.54e-13 0.31
PANC_MYCTU panC Pantothenate synthetase 1.177e-12 0.37
AHK4_ARATH AHK4 Histidine kinase 4 1.608e-12 0.31
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.945e-12 0.40
TYRO_MOUSE Tyr Tyrosinase 5.251e-12 0.29
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.899e-11 0.38
ANO2_HUMAN ANO2 Anoctamin-2 2.363e-11 0.31
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.944e-11 0.33
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 5.834e-11 0.34
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 6.171e-10 0.29
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 8.972e-10 0.28
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 1.038e-09 0.34
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.195e-09 0.33
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.76e-09 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.209e-09 0.32
V2R_RAT Avpr2 Vasopressin V2 receptor 3.877e-09 0.33
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 1.161e-08 0.30
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.939e-08 0.30
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 6.816e-08 0.30
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 6.922e-08 0.36
KLK1_HUMAN KLK1 Kallikrein-1 1.094e-07 0.35
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.615e-07 0.33
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 1.788e-07 0.32
GATA4_MOUSE Gata4 Transcription factor GATA-4 1.84e-07 0.31
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 1.84e-07 0.31
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 2.347e-07 0.30
TRYP_PIG Trypsin 2.571e-07 0.35
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 2.68e-07 0.28
FA12_HUMAN F12 Coagulation factor XII 3.132e-07 0.29
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.66e-07 0.32
LUCI_PHOPY Luciferin 4-monooxygenase 5.656e-07 0.37
DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 6.322e-07 0.28
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 7.295e-07 0.30
NOX1_HUMAN NOX1 NADPH oxidase 1 1.132e-06 0.32
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 1.621e-06 0.33
AGP1_YEAST AGP1 General amino acid permease AGP1 1.778e-06 0.32
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 1.814e-06 0.32
HSF1_MOUSE Hsf1 Heat shock factor protein 1 2.616e-06 0.34
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.849e-06 0.29
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.965e-06 0.36
RCOR1_HUMAN RCOR1 REST corepressor 1 3.789e-06 0.33
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.7e-06 0.28
A5H660_SCHMA HDAC8 Histone deacetylase 8 6.575e-06 0.32
SENP6_HUMAN SENP6 Sentrin-specific protease 6 7.935e-06 0.40
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 8.986e-06 0.33
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 9.02e-06 0.36

Bepotastine

CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 3.363e-82 0.34
HRH3_CAVPO HRH3 Histamine H3 receptor 1.499e-48 0.40
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 4.8e-47 0.45
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.351e-45 0.53
O19067_PIG N-methyl-D-aspartate receptor 1.157e-39 0.31
HRH1_HUMAN HRH1 Histamine H1 receptor 1.02e-37 0.49
DRD4_RAT Drd4 D(4) dopamine receptor 2.164e-34 0.38
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.259e-33 0.49
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 9.917e-32 0.38
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 4.531e-30 0.43
KMO_PSEFL kmo Kynurenine 3-monooxygenase 5.049e-30 0.37
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.526e-29 0.42
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 4.085e-27 0.44
MEN1_HUMAN MEN1 Menin 5.552e-27 0.33
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.401e-26 0.36
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.997e-26 0.37
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 9.437e-26 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.869e-25 0.36
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 7.593e-25 0.32
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.685e-24 0.30
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 5.9e-24 0.35
US28_HCMVA US28 G-protein coupled receptor homolog US28 6.855e-24 0.34
DRD1_PIG DRD1 D(1A) dopamine receptor 5.036e-23 0.34
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 5.518e-23 0.28
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.232e-22 0.39
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.17e-22 0.37
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.203e-21 0.40
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 2.734e-21 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 7.739e-21 0.49
Q9WTR4_RAT Slc6a2 Transporter 1.239e-20 0.40
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.831e-20 0.36
HRH1_RAT Hrh1 Histamine H1 receptor 6.252e-20 0.39
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.516e-19 0.30
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.065e-19 0.33
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.063e-19 0.37
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 9.46e-19 0.49
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 9.586e-19 0.49
HRH1_CAVPO HRH1 Histamine H1 receptor 1.423e-18 0.49
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.605e-18 0.49
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 8.414e-18 0.35
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.525e-17 0.47
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.778e-17 0.49
TYTR_TRYBB TPR Trypanothione reductase 2.942e-17 0.30
NK2R_HUMAN TACR2 Substance-K receptor 1.11e-16 0.49
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 2.22e-16 0.33
H10_HUMAN H1-0 Histone H1.0 7.772e-16 0.30
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.221e-15 0.49
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.443e-15 0.32
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.443e-15 0.35
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 5.551e-15 0.40
DRD2_RAT Drd2 D(2) dopamine receptor 1.577e-14 0.35
HRP1_PLAFA Histidine-rich protein PFHRP-II 1.887e-14 0.30
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 2.498e-14 0.31
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.609e-14 0.40
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 2.609e-14 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.413e-13 0.39
GSHR_PLAF7 GR3 Glutathione reductase 3.164e-13 0.29
OGA_RAT Oga Protein O-GlcNAcase 3.922e-13 0.29
OPRX_MOUSE Oprl1 Nociceptin receptor 4.673e-13 0.28
CASB_RAT Csn2 Beta-casein 5.641e-13 0.28
HRH2_HUMAN HRH2 Histamine H2 receptor 7.775e-13 0.49
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 9.293e-13 0.29
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 1.267e-12 0.31
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 1.267e-12 0.31
DRD5_HUMAN DRD5 D(1B) dopamine receptor 2.171e-12 0.32
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.889e-12 0.47
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.499e-12 0.40
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.795e-12 0.31
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.536e-12 0.49
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 8.165e-12 0.29
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.165e-11 0.49
PLD1_RAT Pld1 Phospholipase D1 1.295e-11 0.32
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 1.304e-11 0.28
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.754e-11 0.31
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.068e-11 0.49
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 2.823e-11 0.30
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 3.723e-11 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 5.493e-11 0.38
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 5.711e-11 0.35
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 6.906e-11 0.34
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.082e-10 0.29
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 1.479e-10 0.28
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.526e-10 0.34
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 2.634e-10 0.34
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 3.297e-10 0.38
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 6.228e-10 0.34
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 7.61e-10 0.49
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 9.247e-10 0.34
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 9.533e-10 0.49
DRD5_RAT Drd5 D(1B) dopamine receptor 9.852e-10 0.28
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.326e-09 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.161e-09 0.35
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.474e-09 0.35
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.564e-09 0.32
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 4.736e-09 0.34
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 4.923e-09 0.30
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 5.609e-09 0.34
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.576e-08 0.30
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.586e-08 0.36
PLD1_HUMAN PLD1 Phospholipase D1 1.897e-08 0.32
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.22e-08 0.49
ACES_ELEEL ache Acetylcholinesterase 4.34e-08 0.56
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 5.19e-08 0.31
PLD2_HUMAN PLD2 Phospholipase D2 5.932e-08 0.32
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 7.249e-08 0.30
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 9.513e-08 0.31
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.054e-07 0.49
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.256e-07 0.49
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.348e-07 0.34
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.477e-07 0.31
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.301e-07 0.49
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 4.267e-07 0.40
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 4.547e-07 0.35
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 4.641e-07 0.31
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 5.008e-07 0.33
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 5.815e-07 0.28
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.858e-07 0.49
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.314e-07 0.49
DRD1_HUMAN DRD1 D(1A) dopamine receptor 7.653e-07 0.49
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 8.501e-07 0.30
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.32e-06 0.40
ACLY_HUMAN ACLY ATP-citrate synthase 1.595e-06 0.29
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.041e-06 0.49
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.319e-06 0.49
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.542e-06 0.49
CNR1_HUMAN CNR1 Cannabinoid receptor 1 2.724e-06 0.42
PI2R_HUMAN PTGIR Prostacyclin receptor 3.11e-06 0.39
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.183e-06 0.32
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 5.71e-06 0.38
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.451e-06 0.30
THAS_HUMAN TBXAS1 Thromboxane-A synthase 8.909e-06 0.32
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 9.098e-06 0.35

Gluconolactone

CDD_HUMAN CDA Cytidine deaminase 1.435e-81 0.35
CDD_MOUSE Cda Cytidine deaminase 8.717e-75 0.35
PYGB_HUMAN PYGB Glycogen phosphorylase, brain form 3.293e-57 0.37
MANBA_HUMAN MANBA Beta-mannosidase 5.433e-56 0.37
B4EH87_BURCJ Lectin 7.873e-55 0.39
TREA_HUMAN TREH Trehalase 2.85e-39 0.31
ADA_MOUSE Ada Adenosine deaminase 1.208e-27 0.34
KLRBA_RAT Klrb1a Killer cell lectin-like receptor subfamily B member 1A 5.722e-25 0.32
HEXB_HUMAN HEXB Beta-hexosaminidase subunit beta 2.158e-24 0.30
KITH_VZVD TK Thymidine kinase 1.331e-20 0.31
A3RLP8_CHV1 UL23 Thymidine kinase 1.861e-20 0.29
GLCM_BOVIN GBA Lysosomal acid glucosylceramidase 4.884e-19 0.30
HEXA_HUMAN HEXA Beta-hexosaminidase subunit alpha 6.741e-19 0.30
KITH_HUMAN TK1 Thymidine kinase, cytosolic 4.795e-17 0.30
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.11e-16 0.32
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 7.772e-16 0.37
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 6.328e-15 0.28
Q2U7N3_ASPOR Beta-galactosidase 1.153e-11 0.38
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 1.275e-11 0.28
Q8AAK6_BACTN Beta-mannosidase 1.339e-11 0.28
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.03e-11 0.37
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 4.052e-11 0.39
IL6_HUMAN IL6 Interleukin-6 7.986e-08 0.31
BGAL_HUMAN GLB1 Beta-galactosidase 5.865e-07 0.30
BGAL_BOVIN GLB1 Beta-galactosidase 3.153e-06 0.38

Lofexidine

ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 5.824e-76 0.72
NISCH_HUMAN NISCH Nischarin 6.118e-69 0.53
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.419e-65 0.72
NISCH_RAT Nisch Nischarin 2.775e-61 0.53
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.086e-55 0.72
G3HDX1_CRIGR Alpha-1B adrenergic receptor 1.882e-17 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 5.636e-08 0.35
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.848e-07 0.33

Permethrin

GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 2.749e-72 0.31
CRTM_STAAU crtM 4,4'-diapophytoene synthase 9.535e-68 0.37
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 3.226e-43 0.30
PPCE_ELIME f1pep1 Prolyl endopeptidase 1.023e-37 0.30
A5K1A2_PLAVS Glycylpeptide N-tetradecanoyltransferase 2.873e-37 0.29
EPOR_HUMAN EPOR Erythropoietin receptor 4.763e-37 0.31
KAT1_HUMAN KYAT1 Kynurenine--oxoglutarate transaminase 1 1.377e-35 0.28
GLT_PYRHO Glutamate transporter homolog 1.609e-35 0.28
PPCE_MOUSE Prep Prolyl endopeptidase 1.55e-34 0.34
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 9.304e-34 0.31
AMP1_PLAFQ M1 family aminopeptidase 1.14e-27 0.38
GHSR_MOUSE Ghsr Growth hormone secretagogue receptor type 1 3.317e-24 0.30
FDFT_HUMAN FDFT1 Squalene synthase 5.307e-24 0.35
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 1.062e-23 0.41
Q6RY99_RAT Tetraspanin 4.37e-22 0.31
MCL1_MOUSE Mcl1 Induced myeloid leukemia cell differentiation protein Mcl-1 homolog 2.084e-21 0.31
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.223e-20 0.31
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 7.203e-20 0.41
Q9Z1J7_RAT Slc1a5 Amino acid transporter 7.598e-20 0.32
Q4WLT4_ASPFU 1,3-beta-glucan synthase catalytic subunit FksP 2.036e-19 0.31
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 6.845e-19 0.37
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 9.056e-18 0.28
DGLA_MOUSE Dagla Sn1-specific diacylglycerol lipase alpha 4.763e-17 0.35
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 1.11e-16 0.32
O13428_CANAX GSC1 Beta-1,3-glucan synthase catalytic subunit 1 3.331e-16 0.31
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 7.883e-15 0.28
MGLL_MOUSE Mgll Monoglyceride lipase 1.144e-14 0.33
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 6.672e-14 0.30
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 4.45e-13 0.29
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 1.498e-12 0.37
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.749e-12 0.31
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 4.37e-11 0.32
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 7.655e-11 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 9.986e-11 0.35
FDFT_RAT Fdft1 Squalene synthase 2.312e-10 0.41
CETP_RABIT CETP Cholesteryl ester transfer protein 2.544e-10 0.31
Q25615_ONCVO Chitinase 3.067e-10 0.29
AROK_HELPY aroK Shikimate kinase 7.549e-10 0.31
PPCE_BOVIN PREP Prolyl endopeptidase 1.516e-09 0.30
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.894e-09 0.31
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.901e-09 0.46
A3EZJ3_9HEPC NS3 Genome polyprotein 3.137e-09 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.228e-09 0.31
CATB_BOVIN CTSB Cathepsin B 9.197e-09 0.31
F13A_HUMAN F13A1 Coagulation factor XIII A chain 9.793e-09 0.38
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 1.4e-08 0.30
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.512e-08 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.304e-08 0.34
NMT_PLAF7 Glycylpeptide N-tetradecanoyltransferase 3.43e-08 0.34
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 8.215e-08 0.38
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.106e-07 0.30
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.573e-07 0.34
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 1.86e-07 0.31
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 4.112e-07 0.33
BLA1_ECOLX bla Beta-lactamase SHV-1 4.511e-07 0.30
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 4.707e-07 0.30
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 6.187e-07 0.35
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 9.298e-07 0.30
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 9.354e-07 0.33
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.133e-06 0.30
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.233e-06 0.31
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.237e-06 0.38
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.854e-06 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 2.072e-06 0.32
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 2.928e-06 0.37
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 3.241e-06 0.35
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.416e-06 0.41
LYOX_HUMAN LOX Protein-lysine 6-oxidase 3.933e-06 0.30
ELNE_HUMAN ELANE Neutrophil elastase 5.406e-06 0.33
FEN1_HUMAN FEN1 Flap endonuclease 1 6.975e-06 0.33
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 7.284e-06 0.31

Celiprolol

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 9.67e-69 0.43
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 3.184e-68 0.29
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.191e-63 0.43
CASR_BOVIN CASR Extracellular calcium-sensing receptor 8.297e-37 0.29
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 4.155e-34 0.34
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.23e-31 0.40
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.99e-31 0.43
CASR_HUMAN CASR Extracellular calcium-sensing receptor 1.748e-19 0.34
ANDR_MOUSE Ar Androgen receptor 1.994e-19 0.32
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.149e-18 0.31
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 1.25e-18 0.40
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 4.032e-13 0.28
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 1.665e-12 0.56
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.099e-10 0.32
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.355e-10 0.31
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.666e-10 0.36
CASR_RAT Casr Extracellular calcium-sensing receptor 6.442e-10 0.32
VDR_HUMAN VDR Vitamin D3 receptor 4.008e-08 0.32
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 3.786e-07 0.41
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 8.453e-07 0.42
PRIO_SHEEP PRNP Major prion protein 1.611e-06 0.30
B4URF0_I33A0 Neuraminidase 1.685e-06 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 6.191e-06 0.32

Hesperidin

T2R31_HUMAN TAS2R31 Taste receptor type 2 member 31 3.897e-68 0.48
CD22_HUMAN CD22 B-cell receptor CD22 2.594e-51 0.30
TYRO_MOUSE Tyr Tyrosinase 1.719e-37 0.33
GOB1_BRUMA Trehalose-phosphatase 6.145e-36 0.28
DCOR_HUMAN ODC1 Ornithine decarboxylase 1.144e-33 0.39
CD22_MOUSE Cd22 B-cell receptor CD22 5.799e-27 0.30
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.129e-26 0.46
IL2_HUMAN IL2 Interleukin-2 2.461e-23 0.39
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 8.868e-22 0.31
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 1.398e-18 0.29
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 5.924e-18 0.28
O96394_LEIAM Arginase 3.501e-17 0.30
B4EH87_BURCJ Lectin 4.441e-16 0.31
KLK2_HUMAN KLK2 Kallikrein-2 2.043e-13 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.504e-13 0.42
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 3.926e-12 0.29
ACES_RAT Ache Acetylcholinesterase 6.022e-12 0.54
CBS_HUMAN CBS Cystathionine beta-synthase 8.4e-11 0.29
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 2.079e-10 0.30
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 6.717e-10 0.57
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 1.072e-09 0.28
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 1.091e-09 0.30
TYRO_HUMAN TYR Tyrosinase 2.026e-09 0.31
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 5.043e-08 0.30
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 1.095e-07 0.51
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 1.35e-07 0.28
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.263e-06 0.42
CP19A_HUMAN CYP19A1 Aromatase 2.624e-06 0.63
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 2.738e-06 0.40
R1AB_SARS rep Replicase polyprotein 1ab 7.888e-06 0.57
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 7.932e-06 0.32
B4URF0_I33A0 Neuraminidase 8.285e-06 0.62
IL5_MOUSE Il5 Interleukin-5 8.822e-06 0.30

Ergosterol

DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 1.144e-67 0.41
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 4.067e-39 0.31
VDR_BOVIN VDR Vitamin D3 receptor 2.367e-36 0.28
CP125_MYCTU cyp125 Steroid C26-monooxygenase 2.026e-28 0.35
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 2.325e-27 0.34
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 5.151e-27 0.35
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 8.657e-24 0.29
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.642e-22 0.41
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 6.896e-20 0.32
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.871e-18 0.34
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.11e-16 0.35
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.11e-16 0.64
VDR_HUMAN VDR Vitamin D3 receptor 4.441e-16 0.38
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 7.772e-16 0.33
FGF2_HUMAN FGF2 Fibroblast growth factor 2 7.994e-15 0.32
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.115e-10 0.33
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 9.429e-10 0.31
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.482e-09 0.30
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.22e-09 0.29
NR1H4_MOUSE Nr1h4 Bile acid receptor 1.419e-08 0.42
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.788e-07 0.34
RXRA_MOUSE Rxra Retinoic acid receptor RXR-alpha 3.321e-07 0.42
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.058e-06 0.31
VDR_RAT Vdr Vitamin D3 receptor 3.471e-06 0.30

Iodipamide

ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.851e-57 0.35
RCOR3_HUMAN RCOR3 REST corepressor 3 6.888e-48 0.38
Q9XYC7_PLAFA HDAC1 Histone deacetylase 8.118e-31 0.38
Q7K6A1_PLAF7 Histone deacetylase 9.074e-24 0.38
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.295e-18 0.38
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.787e-17 0.40
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 1.11e-16 0.38
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 2.22e-16 0.38
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.331e-16 0.38
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 3.109e-15 0.29
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.441e-15 0.40
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 1.266e-14 0.36
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.821e-14 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.79e-12 0.38
HDAC9_HUMAN HDAC9 Histone deacetylase 9 7.338e-11 0.38
HDAC5_HUMAN HDAC5 Histone deacetylase 5 9.894e-11 0.38
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.41e-10 0.38
A5H660_SCHMA HDAC8 Histone deacetylase 8 7.527e-10 0.41
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 3.969e-09 0.38
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.293e-08 0.38
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.445e-08 0.35
HDAC4_HUMAN HDAC4 Histone deacetylase 4 1.555e-08 0.38
HDAC1_MOUSE Hdac1 Histone deacetylase 1 8.101e-07 0.38
POLG_DEN2P Genome polyprotein 9.396e-07 0.29
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.306e-06 0.33
HDAH_ALCSD hdaH Histone deacetylase-like amidohydrolase 6.801e-06 0.38

Fructose

PYGB_HUMAN PYGB Glycogen phosphorylase, brain form 3.293e-57 0.37
B4EH87_BURCJ Lectin 2.366e-48 0.34
TREA_BOMMO Trehalase 9.719e-24 0.29
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 6.11e-12 0.30
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.125e-11 0.37
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.345e-08 0.34
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 3.289e-08 0.30
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.476e-06 0.33
LYAG_HUMAN GAA Lysosomal alpha-glucosidase 4.799e-06 0.35

Pyrophosphoric_acid

ISPH_AQUAE ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 6.563e-55 0.39
B1LRJ1_ECOSM traI Type IV secretion-like conjugative transfer relaxase protein TraI 9.818e-49 0.33
TPIS_HUMAN TPI1 Triosephosphate isomerase 1.312e-47 0.30
TPIS_RABIT TPI1 Triosephosphate isomerase 1.312e-47 0.30
IP3KA_RAT Itpka Inositol-trisphosphate 3-kinase A 5.166e-42 0.33
ITPR3_BOVIN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 5.678e-42 0.37
ALF_ECOLI fbaA Fructose-bisphosphate aldolase class 2 1.947e-38 0.30
ALDOA_RABIT ALDOA Fructose-bisphosphate aldolase A 2.642e-38 0.32
MVD1_HUMAN MVD Diphosphomevalonate decarboxylase 2.917e-35 0.31
ITPR3_HUMAN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1.523e-33 0.35
PLCL1_RAT Plcl1 Inactive phospholipase C-like protein 1 5.245e-27 0.33
BT3A1_HUMAN BTN3A1 Butyrophilin subfamily 3 member A1 4.92e-23 0.32
P79248_PIG Type 1 InsP3 receptor isoform S2 6.654e-21 0.33
ALF_TRYBB ALD Fructose-bisphosphate aldolase, glycosomal 5.429e-20 0.32
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 6.741e-19 0.30
ITPR1_HUMAN ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 1.463e-13 0.33
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 1.463e-13 0.33
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 1.424e-11 0.35
MURA_ECOLI murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3.542e-11 0.30

Clofedanol

Q5TIX5_MYCSM atpE ATP synthase subunit c 3.612e-53 0.29
ATP6_MYCTU atpB ATP synthase subunit a 1.631e-52 0.36
ATPA_MYCTU atpA ATP synthase subunit alpha 1.631e-52 0.36
ATPB_MYCTU atpD ATP synthase subunit beta 1.631e-52 0.36
ATPE_MYCTU atpC ATP synthase epsilon chain 1.631e-52 0.36
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 1.631e-52 0.36
ATPF_MYCTU atpF ATP synthase subunit b 1.631e-52 0.36
ATPG_MYCTU atpG ATP synthase gamma chain 1.631e-52 0.36
ATPL_MYCTU atpE ATP synthase subunit c 1.631e-52 0.36
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 2.01e-37 0.35
ATPL_BACP3 atpE ATP synthase subunit c 1.195e-36 0.29
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.338e-26 0.30
DXS_HAEI8 dxs 1-deoxy-D-xylulose-5-phosphate synthase 2.158e-24 0.30
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 2.331e-15 0.42
ISPA_ECOLI ispA Farnesyl diphosphate synthase 4.43e-14 0.31
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.487e-12 0.31
CALM_BOVIN CALM Calmodulin 5.24e-11 0.30
Q8WMX0_BOVIN Muscarinic receptor M1 8.608e-09 0.30
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.397e-08 0.31
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.352e-08 0.47
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 7.918e-08 0.47
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.171e-07 0.34
CP19A_RAT Cyp19a1 Aromatase 3.387e-07 0.34
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.044e-06 0.29

Nialamide

SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.809e-48 0.35
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 6.896e-48 0.31
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 3.699e-44 0.42
SENP1_HUMAN SENP1 Sentrin-specific protease 1 3.674e-43 0.35
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.219e-40 0.32
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.627e-37 0.30
SENP2_HUMAN SENP2 Sentrin-specific protease 2 5.953e-37 0.29
PGDA2_BACCR Peptidoglycan-N-acetylglucosamine deacetylase BC_1974 8.333e-36 0.28
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 9.122e-36 0.36
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.385e-35 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.385e-32 0.43
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 2.174e-30 0.40
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 7.993e-29 0.37
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 2.676e-25 0.38
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.775e-25 0.41
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.245e-24 0.44
POLG_CXB3N Genome polyprotein 1.037e-23 0.39
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.414e-23 0.56
ACES_TETCF ache Acetylcholinesterase 1.1e-22 0.32
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.386e-22 0.31
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.796e-22 0.36
SUCR1_RAT Sucnr1 Succinate receptor 1 2.323e-22 0.28
CHLE_HUMAN BCHE Cholinesterase 2.018e-21 0.43
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.01e-20 0.37
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.977e-20 0.44
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 4.69e-20 0.40
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 8.529e-20 0.35
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 1.071e-19 0.47
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.298e-19 0.40
VE1_HPV11 E1 Replication protein E1 4.303e-19 0.36
HDAC8_HUMAN HDAC8 Histone deacetylase 8 8.646e-19 0.44
SUCR1_HUMAN SUCNR1 Succinate receptor 1 8.802e-19 0.35
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.229e-18 0.40
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 1.437e-18 0.33
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.957e-18 0.29
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 5.861e-18 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 6.092e-18 0.29
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 6.589e-18 0.37
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 8.343e-18 0.38
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 8.376e-18 0.30
OXGR1_HUMAN OXGR1 2-oxoglutarate receptor 1 8.52e-18 0.28
PADI6_HUMAN PADI6 Protein-arginine deiminase type-6 8.52e-18 0.28
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 2.54e-17 0.37
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.709e-17 0.56
STABP_HUMAN STAMBP STAM-binding protein 5.3e-17 0.35
TRAP_STAAM traP Signal transduction protein TRAP 1.11e-16 0.29
PEPT1_DERPT DERP1 Peptidase 1 3.331e-16 0.32
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 3.331e-16 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 7.772e-16 0.39
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.882e-16 0.40
AMPN_PIG ANPEP Aminopeptidase N 1.11e-15 0.42
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.776e-15 0.30
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 4.33e-15 0.36
FURIN_HUMAN FURIN Furin 4.441e-15 0.30
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.288e-14 0.42
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 2.653e-14 0.46
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 4.718e-14 0.42
AMP1_PLAFQ M1 family aminopeptidase 5.218e-14 0.33
EGFR_MOUSE Egfr Epidermal growth factor receptor 6.717e-14 0.32
ACES_HUMAN ACHE Acetylcholinesterase 6.761e-14 0.32
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 1.007e-13 0.34
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 1.587e-13 0.56
GYRB_MYCS2 gyrB DNA gyrase subunit B 1.691e-13 0.32
BODG_PSESK Gamma-butyrobetaine dioxygenase 2.343e-13 0.29
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 3.416e-13 0.38
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 3.996e-13 0.42
TRY1_RAT Prss1 Anionic trypsin-1 3.996e-13 0.31
UPAR_RAT Plaur Urokinase plasminogen activator surface receptor 3.996e-13 0.31
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 5.076e-13 0.31
KLKB1_HUMAN KLKB1 Plasma kallikrein 5.971e-13 0.38
PANC_MYCTU panC Pantothenate synthetase 1.331e-12 0.34
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.393e-12 0.39
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.393e-12 0.39
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.4e-12 0.31
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 1.557e-12 0.56
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.565e-12 0.36
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.698e-12 0.38
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 4.675e-12 0.46
CTNB1_HUMAN CTNNB1 Catenin beta-1 5.207e-12 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.45e-12 0.39
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 6.139e-12 0.29
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 6.213e-12 0.37
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 6.328e-12 0.30
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 6.439e-12 0.56
ADH1G_HUMAN ADH1C Alcohol dehydrogenase 1C 7.334e-12 0.29
THRB_HUMAN F2 Prothrombin 8.675e-12 0.34
TRXR1_HUMAN TXNRD1 Thioredoxin reductase 1, cytoplasmic 1.196e-11 0.28
THAS_HUMAN TBXAS1 Thromboxane-A synthase 1.222e-11 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.453e-11 0.37
ACES_MOUSE Ache Acetylcholinesterase 1.486e-11 0.42
NEP_RAT Mme Neprilysin 3.166e-11 0.35
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 4.854e-11 0.56
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 6.249e-11 0.32
PA_I34A1 PA Polymerase acidic protein 8.573e-11 0.34
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 8.615e-11 0.35
RS27_HUMAN RPS27 40S ribosomal protein S27 9.3e-11 0.29
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 1.135e-10 0.31
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 1.214e-10 0.34
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 1.267e-10 0.56
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.577e-10 0.28
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.748e-10 0.31
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 2.292e-10 0.35
KLK1_HUMAN KLK1 Kallikrein-1 2.869e-10 0.32
ACOD_HUMAN SCD Acyl-CoA desaturase 3.515e-10 0.34
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.847e-10 0.40
CHLE_HORSE BCHE Cholinesterase 5.385e-10 0.40
TF_HUMAN F3 Tissue factor 5.729e-10 0.36
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 7.814e-10 0.36
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 8.013e-10 0.33
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 8.972e-10 0.28
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 8.972e-10 0.28
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 9.461e-10 0.56
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 9.726e-10 0.56
CTRA_BOVIN Chymotrypsinogen A 1.097e-09 0.37
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 1.427e-09 0.37
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.49e-09 0.38
EGLN1_HUMAN EGLN1 Egl nine homolog 1 1.536e-09 0.39
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.738e-09 0.31
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.948e-09 0.56
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.967e-09 0.35
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 2.025e-09 0.37
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 2.155e-09 0.39
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 2.335e-09 0.33
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.533e-09 0.29
ADH1B_HUMAN ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 2.903e-09 0.29
AA1R_BOVIN ADORA1 Adenosine receptor A1 3.367e-09 0.38
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 3.486e-09 0.38
FUCO_BOVIN FUCA1 Tissue alpha-L-fucosidase 3.826e-09 0.36
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 4.285e-09 0.30
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 4.33e-09 0.56
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 4.388e-09 0.41
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 4.864e-09 0.28
Q533H1_FELCA UTS2R Urotensin II receptor 5.048e-09 0.28
NEP_RABIT MME Neprilysin 5.097e-09 0.32
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 5.367e-09 0.30
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.825e-09 0.36
Q76129_9HIV1 gag Structural capsid protein 6.084e-09 0.31
CAH7_HUMAN CA7 Carbonic anhydrase 7 6.117e-09 0.42
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 6.744e-09 0.56
THRB_RAT F2 Prothrombin 7.334e-09 0.31
CAH2_BOVIN CA2 Carbonic anhydrase 2 9.844e-09 0.37
CATL1_BOVIN CTSL Cathepsin L1 1.237e-08 0.30
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.31e-08 0.39
VHL_HUMAN VHL von Hippel-Lindau disease tumor suppressor 1.318e-08 0.32
PRIO_HUMAN PRNP Major prion protein 1.909e-08 0.32
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 2.142e-08 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.357e-08 0.43
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 2.902e-08 0.33
CAH4_HUMAN CA4 Carbonic anhydrase 4 3.113e-08 0.42
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.378e-08 0.42
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 3.503e-08 0.40
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 3.931e-08 0.48
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 4.852e-08 0.31
HDA11_HUMAN HDAC11 Histone deacetylase 11 6.069e-08 0.36
CAH2_HUMAN CA2 Carbonic anhydrase 2 6.077e-08 0.42
CAH1_HUMAN CA1 Carbonic anhydrase 1 6.354e-08 0.62
ACES_ELEEL ache Acetylcholinesterase 6.539e-08 0.40
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 6.671e-08 0.43
Q9JKC1_RAT Bche Carboxylic ester hydrolase 6.838e-08 0.29
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 7.821e-08 0.56
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 8.922e-08 0.32
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 9.065e-08 0.30
LEG7_HUMAN LGALS7; LGALS7B Galectin-7 1.031e-07 0.29
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.031e-07 0.35
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.14e-07 0.40
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.206e-07 0.40
SCAF_HHV11 UL26 Capsid scaffolding protein 1.324e-07 0.28
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.396e-07 0.39
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.564e-07 0.38
RCOR1_HUMAN RCOR1 REST corepressor 1 1.588e-07 0.30
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 1.617e-07 0.36
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.533e-07 0.39
KPCA_HUMAN PRKCA Protein kinase C alpha type 2.718e-07 0.39
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 2.898e-07 0.37
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.122e-07 0.32
ACES_BOVIN ACHE Acetylcholinesterase 3.163e-07 0.29
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 3.262e-07 0.38
GATA4_MOUSE Gata4 Transcription factor GATA-4 3.374e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 3.374e-07 0.29
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 3.375e-07 0.31
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 3.52e-07 0.38
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.634e-07 0.62
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.635e-07 0.33
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 3.712e-07 0.30
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 3.784e-07 0.34
AMPN_HUMAN ANPEP Aminopeptidase N 4.437e-07 0.33
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 5.045e-07 0.56
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 5.06e-07 0.30
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 5.186e-07 0.33
CRTM_STAAU crtM 4,4'-diapophytoene synthase 5.238e-07 0.28
BCAT1_HUMAN BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic 5.533e-07 0.28
CAN_CANAL NCE103 Carbonic anhydrase 5.62e-07 0.39
Q6FTL6_CANGA NCE103 Carbonic anhydrase 6.276e-07 0.31
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 6.284e-07 0.31
LYOX_HUMAN LOX Protein-lysine 6-oxidase 9.875e-07 0.33
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 1.054e-06 0.28
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.211e-06 0.33
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 1.281e-06 0.34
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 1.4e-06 0.56
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.674e-06 0.29
LEG9_HUMAN LGALS9 Galectin-9 1.683e-06 0.29
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.693e-06 0.33
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.702e-06 0.30
TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 1.718e-06 0.32
KPCG_HUMAN PRKCG Protein kinase C gamma type 1.721e-06 0.56
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 1.784e-06 0.31
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.794e-06 0.29
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 1.886e-06 0.31
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.913e-06 0.34
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.243e-06 0.38
FA7_HUMAN F7 Coagulation factor VII 2.492e-06 0.32
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.271e-06 0.49
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 3.325e-06 0.41
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.351e-06 0.38
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 3.543e-06 0.33
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.573e-06 0.36
Q7ZJM1_9HIV1 pol Integrase 3.938e-06 0.34
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.19e-06 0.38
PAPA1_CARPA Papain 4.318e-06 0.30
GRIA4_RAT Gria4 Glutamate receptor 4 4.519e-06 0.33
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 4.712e-06 0.34
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 6.123e-06 0.36
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 6.18e-06 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 6.571e-06 0.32
CAH14_HUMAN CA14 Carbonic anhydrase 14 6.611e-06 0.42
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 6.8e-06 0.35
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 6.874e-06 0.38
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 8.201e-06 0.38
Q38C41_TRYB2 Phosphotransferase 8.461e-06 0.35
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 9.269e-06 0.38
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 9.511e-06 0.38

Lactic_acid

LEU3_THET8 leuB 3-isopropylmalate dehydrogenase 6.888e-48 0.38
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 2.543e-40 0.33
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 6.694e-38 0.30
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 2.702e-27 0.42
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 2.162e-26 0.31
DAPE_HAEIN dapE Succinyl-diaminopimelate desuccinylase 8.092e-26 0.32
GLN1B_ECOLI glnA Glutamine synthetase 1.914e-25 0.29
CBPA1_BOVIN CPA1 Carboxypeptidase A1 5.231e-20 0.35
AMPN_ECOLI pepN Aminopeptidase N 2.322e-19 0.31
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 3.352e-19 0.37
Q6RY99_RAT Tetraspanin 1.232e-14 0.40
AMPB_HUMAN RNPEP Aminopeptidase B 5.618e-14 0.38
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 9.824e-13 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 2.335e-11 0.33
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 2.041e-10 0.37
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.167e-09 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.322e-08 0.29
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 9.381e-08 0.33
ALBU_BOVIN ALB Serum albumin 1.848e-07 0.33
PGH2_BOVIN PTGS2 Prostaglandin G/H synthase 2 3.409e-07 0.33
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 6.707e-07 0.37
GRIK3_HUMAN GRIK3 Glutamate receptor ionotropic, kainate 3 1.683e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 2.917e-06 0.30
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 3.097e-06 0.32
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 4.379e-06 0.35

Cyclandelate

Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 8.414e-45 0.36
Q8WSF8_APLCA Soluble acetylcholine receptor 3.452e-41 0.35
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.609e-35 0.28
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.476e-33 0.39
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 5.522e-28 0.39
ACHP_LYMST Acetylcholine-binding protein 2.115e-23 0.35
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 6.785e-18 0.28
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 4.441e-16 0.39
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.554e-15 0.38
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 9.215e-14 0.39
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.65e-11 0.39
Q8WMX0_BOVIN Muscarinic receptor M1 6.147e-11 0.38
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 3.924e-08 0.38
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 7.4e-08 0.32
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.193e-07 0.55
CXCR5_HUMAN CXCR5 C-X-C chemokine receptor type 5 6.739e-07 0.30
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 9.337e-07 0.32
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.183e-06 0.55
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.734e-06 0.30
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 4.621e-06 0.36
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.024e-06 0.55
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 5.273e-06 0.40
AMPL_PIG LAP3 Cytosol aminopeptidase 5.293e-06 0.32
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.805e-06 0.55

Latamoxef

CMA1_HUMAN CMA1 Chymase 3.027e-41 0.69
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 3.357e-27 0.47
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 4.989e-23 0.28
B2ZTR6_ACIBA Beta-lactamase 2.214e-22 0.36
D6NSM8_ACIBA ampC Beta-lactamase 2.214e-22 0.36
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.265e-17 0.47
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.11e-16 0.47
A2RP81_CITFR blaPER-2 Beta-lactamase 3.331e-16 0.36
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.607e-08 0.28
CATG_HUMAN CTSG Cathepsin G 3.835e-06 0.57

Propanoic_acid

E5KIY2_ECOLX blaNDM-1 Beta-lactamase 7.545e-40 0.32
GBRT_HUMAN GABRQ Gamma-aminobutyric acid receptor subunit theta 7.545e-40 0.32
S6A13_RAT Slc6a13 Sodium- and chloride-dependent GABA transporter 2 7.545e-40 0.32
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 1.53e-39 0.33
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 3.585e-30 0.35
S22AK_MOUSE Slc22a20 Solute carrier family 22 member 20 4.743e-27 0.30
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 2.158e-24 0.30
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 2.774e-23 0.33
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 1.144e-22 0.29
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 7.396e-20 0.32
KDM7A_HUMAN KDM7A Lysine-specific demethylase 7A 3.691e-19 0.30
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 6.741e-19 0.30
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 7.617e-19 0.31
PURA2_HUMAN ADSS2 Adenylosuccinate synthetase isozyme 2 4.879e-18 0.29
EST1_RABIT Liver carboxylesterase 1 1.11e-16 0.33
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.11e-16 0.32
ACEA_CANAX ICL1 Isocitrate lyase 4.441e-15 0.29
CGL_HUMAN CTH Cystathionine gamma-lyase 1.463e-13 0.33
S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.801e-13 0.40
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 6.857e-13 0.33
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 1.898e-12 0.42
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.938e-12 0.53
CBS_HUMAN CBS Cystathionine beta-synthase 2.492e-12 0.33
Q6RY99_RAT Tetraspanin 2.492e-12 0.33
EST2_HUMAN CES2 Cocaine esterase 5.12e-12 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.421e-10 0.32
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 5.985e-10 0.33
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.201e-09 0.32
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.6e-08 0.42
EST1_HUMAN CES1 Liver carboxylesterase 1 9.171e-08 0.38
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 9.381e-08 0.33
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.07e-07 0.32
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.07e-07 0.32
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.953e-07 0.32
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 1.263e-06 0.32
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.291e-06 0.30
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 2.044e-06 0.32
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.066e-06 0.35
TLR2_HUMAN TLR2 Toll-like receptor 2 2.596e-06 0.42
ACLY_RAT Acly ATP-citrate synthase 6.365e-06 0.32
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 8.822e-06 0.30
GBRR1_HUMAN GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 9.884e-06 0.32

Oxyphenisatin

TYSY_CRYNB TMP1 Thymidylate synthase 7.903e-40 0.41
TYSY_ECOLI thyA Thymidylate synthase 1.142e-30 0.44
TYSY_ENTFA thyA Thymidylate synthase 1.449e-22 0.44
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 3.449e-12 0.33
TYSY_LACCA thyA Thymidylate synthase 3.116e-10 0.44
WNT3A_MOUSE Wnt3a Protein Wnt-3a 5.445e-10 0.40
C3SWJ7_ECOLX thyA Thymidylate synthase 4.422e-09 0.41
NQO1_HUMAN NQO1 NAD(P)H dehydrogenase [quinone] 1 5.156e-06 0.33

Urethane

PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 2.83e-38 0.30
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 2.464e-31 0.30
DXS_ECO27 dxs 1-deoxy-D-xylulose-5-phosphate synthase 5.827e-26 0.32
DXS_ECOLI dxs 1-deoxy-D-xylulose-5-phosphate synthase 4.22e-20 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.039e-09 0.29
PPM1B_HUMAN PPM1B Protein phosphatase 1B 2.44e-09 0.31
PAPA1_CARPA Papain 2.734e-08 0.43
Q8AWE3_CHICK Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B 1.264e-07 0.31

Bunamiodyl

MSRE_MOUSE Msr1 Macrophage scavenger receptor types I and II 6.694e-38 0.30
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 5.213e-08 0.35
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.124e-06 0.28

Zomepirac

TYTR_TRYBB TPR Trypanothione reductase 4.969e-37 0.32
DHRS9_RAT Dhrs9 Dehydrogenase/reductase SDR family member 9 7.04e-23 0.28
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 2.261e-22 0.37
IL8_HUMAN CXCL8 Interleukin-8 5.91e-21 0.48
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 6.401e-21 0.38
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.339e-20 0.35
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 2.009e-19 0.37
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 3.948e-18 0.35
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 7.888e-18 0.34
EST1_RABIT Liver carboxylesterase 1 1.377e-14 0.37
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 6.128e-14 0.39
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 6.55e-14 0.41
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.167e-13 0.33
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.315e-13 0.39
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 7.021e-13 0.35
KMO_RAT Kmo Kynurenine 3-monooxygenase 7.254e-13 0.33
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 9.884e-13 0.41
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 5.746e-11 0.35
Q9BEG3_BOVIN 5-lipoxygenase 1.266e-10 0.32
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 4.146e-10 0.37
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 4.471e-10 0.41
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.829e-10 0.37
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 8.972e-10 0.28
PPOC_ARATH PPOX1 Protoporphyrinogen oxidase 1, chloroplastic 1.087e-09 0.28
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 4.451e-09 0.31
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 5.947e-09 0.37
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 6.681e-09 0.32
EST2_HUMAN CES2 Cocaine esterase 7.64e-09 0.37
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 1.039e-08 0.37
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 1.383e-08 0.30
TA2R_RAT Tbxa2r Thromboxane A2 receptor 2.672e-08 0.31
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.167e-08 0.40
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 6.511e-08 0.48
E3UJZ5_SPOLI Ecdysone receptor 1.152e-07 0.30
Q3Y5H1_9GAMC 3C-like protease 1.343e-07 0.37
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.721e-07 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.916e-07 0.37
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.064e-07 0.39
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 8.579e-07 0.30
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.053e-06 0.29
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 2.149e-06 0.36
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.324e-06 0.32
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 3.101e-06 0.29
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 3.637e-06 0.32
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 4.596e-06 0.29
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 4.924e-06 0.37
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 7.112e-06 0.29
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 7.864e-06 0.32
ECR_BOMMO EcR Ecdysone receptor 8.009e-06 0.30
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.846e-06 0.35
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.96e-06 0.30

Bithionol

ERMC1_STAAU ermC rRNA adenine N-6-methyltransferase 7.142e-37 0.29
G3V906_RAT Hcar1 Hydroxycarboxylic acid receptor 1 1.377e-35 0.28
ACLY_HUMAN ACLY ATP-citrate synthase 1.056e-19 0.36
Q9BJJ9_PLAFA FabI Enoyl-ACP reductase 1.523e-18 0.29
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 4.628e-12 0.29
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 6.962e-11 0.39
CBR1_HUMAN CBR1 Carbonyl reductase [NADPH] 1 6.44e-08 0.29
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 1.949e-07 0.45
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 3.205e-07 0.29
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.485e-06 0.42
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 4.731e-06 0.42
COMT_RAT Comt Catechol O-methyltransferase 6.253e-06 0.29

Buformin

DHYS_RAT Dhps Deoxyhypusine synthase 9.317e-36 0.41
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.548e-11 0.36
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.767e-11 0.42
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.087e-07 0.36
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 2.945e-06 0.36
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 5.746e-06 0.36

Tienilic_acid

PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 2.505e-35 0.40
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 3.246e-28 0.51
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 5.723e-26 0.36
CD69_HUMAN CD69 Early activation antigen CD69 7.837e-26 0.34
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 4.219e-15 0.33
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 1.412e-12 0.51
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 1.783e-10 0.32
Q962Y6_SCHMA TGR Thioredoxin glutathione reductase 1.819e-08 0.31
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.024e-07 0.32
POLG_DEN2P Genome polyprotein 6.572e-07 0.29
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 8.707e-07 0.32
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 2.347e-06 0.45
KLK7_HUMAN KLK7 Kallikrein-7 2.478e-06 0.36
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 2.849e-06 0.29
SKN1_CAEEL skn-1 Protein skinhead-1 6.347e-06 0.35
AMPC_PSEAE ampC Beta-lactamase 6.542e-06 0.31

Ixabepilone

XBP1_RAT Xbp1 X-box-binding protein 1 1.36e-25 0.29

Thenalidine

CCR5_MACFA CCR5 C-C chemokine receptor type 5 2.419e-25 0.35
TRPM8_HUMAN TRPM8 Transient receptor potential cation channel subfamily M member 8 3.173e-22 0.37
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 3.117e-18 0.34
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 3.117e-18 0.34
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.65e-17 0.46
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 2.22e-16 0.33
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.22e-15 0.46
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.448e-13 0.46
DOPO_BOVIN DBH Dopamine beta-hydroxylase 1.761e-11 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.165e-10 0.41
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.176e-09 0.29
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 3.467e-09 0.29
DRD5_HUMAN DRD5 D(1B) dopamine receptor 3.49e-09 0.33
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 8.748e-09 0.34
NOS1_HUMAN NOS1 Nitric oxide synthase, brain 9.858e-09 0.33
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.26e-08 0.34
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.017e-07 0.30
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.031e-07 0.29
G6PC_HUMAN G6PC Glucose-6-phosphatase 1.511e-07 0.29
BLA1_STEMA Metallo-beta-lactamase L1 type 3 5.62e-07 0.34
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 6.072e-07 0.31
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 6.311e-07 0.38
NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 3.499e-06 0.32
HRH1_HUMAN HRH1 Histamine H1 receptor 3.987e-06 0.36
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 5.192e-06 0.32
LSS_HUMAN LSS Lanosterol synthase 7.794e-06 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 8.115e-06 0.34

Rapacuronium

IF4A1_MOUSE Eif4a1 Eukaryotic initiation factor 4A-I 1.173e-21 0.30
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.154e-13 0.29
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.084e-11 0.71
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 4.004e-11 0.71
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 8.502e-08 0.29

Dequalinium

NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 3.545e-17 0.45
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.519e-09 0.45
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 2.651e-09 0.45
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 1.749e-07 0.29
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 1.162e-06 0.44
CHLE_HUMAN BCHE Cholinesterase 2.377e-06 0.33
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 3.407e-06 0.29

Metamizole

FPR2_HUMAN FPR2 N-formyl peptide receptor 2 5.906e-14 0.40
S100B_HUMAN S100B Protein S100-B 1.422e-13 0.40
E2AK4_HUMAN EIF2AK4 eIF-2-alpha kinase GCN2 8.438e-12 0.30
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.866e-09 0.30
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 3.83e-08 0.48
REV1_HUMAN REV1 DNA repair protein REV1 7.127e-08 0.29
TSPO_RAT Tspo Translocator protein 2.694e-06 0.33

Enoximone

HDAC1_MOUSE Hdac1 Histone deacetylase 1 3.402e-11 0.28
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 2.065e-09 0.36
O49150_SOLTU Lipoxygenase 3.046e-07 0.36

Omacetaxine_mepesuccinate

TF_HUMAN F3 Tissue factor 4.271e-07 0.33