Results of Job: search_7b77f3f6-acfc-4063-9682-dd6eb94d3fdb

Query Target Key Target Name Description P-Value MaxTC

compound_1

THRB_HUMAN F2 Prothrombin 0.9968 1.00
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 7.597e-103 0.73
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.865e-83 0.68
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 2.131e-74 0.70
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 5.687e-68 0.36
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.897e-67 0.56
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.972e-66 0.53
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 7.968e-66 0.39
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.668e-61 0.48
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.954e-57 0.72
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 3.773e-56 0.70
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.189e-55 0.73
VDR_RAT Vdr Vitamin D3 receptor 2.627e-51 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.811e-45 0.56
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 9.387e-45 0.48
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 2.371e-42 0.37
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 4.226e-42 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 6.366e-40 0.33
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.586e-40 0.54
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 3.269e-39 0.49
VDR_PIG VDR Vitamin D3 receptor 4.754e-38 0.30
VTDB_HUMAN GC Vitamin D-binding protein 4.754e-38 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 3.987e-37 0.60
VDRA_DANRE vdra Vitamin D3 receptor A 4.291e-37 0.30
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 8.297e-37 0.29
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.283e-36 0.46
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.654e-34 0.54
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.303e-33 0.45
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.964e-30 0.38
VDR_HUMAN VDR Vitamin D3 receptor 2.132e-29 0.41
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.063e-28 0.38
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.532e-26 0.58
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 6.795e-26 0.32
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 9.144e-26 0.79
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 1.436e-24 0.36
VDR_CHICK VDR Vitamin D3 receptor 2.922e-23 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 4.462e-21 0.43
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.832e-20 0.54
VDR_BOVIN VDR Vitamin D3 receptor 4.921e-20 0.31
NR1H4_HUMAN NR1H4 Bile acid receptor 3.237e-19 0.41
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.344e-18 0.36
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.698e-18 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 1.11e-16 0.49
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.22e-16 0.54
ECR_DROME EcR Ecdysone receptor 2.22e-16 0.30
ANDR_HUMAN AR Androgen receptor 5.551e-16 0.49
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 6.661e-16 0.31
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.663e-15 0.51
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7.438e-15 0.44
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.176e-14 0.70
REST_BORBU resT Telomere resolvase ResT 2.798e-14 0.35
ABCBB_HUMAN ABCB11 Bile salt export pump 3.186e-14 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.619e-14 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 8.215e-13 0.53
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 1.559e-12 0.53
ESR1_HUMAN ESR1 Estrogen receptor 3.32e-12 0.49
ANDR_RAT Ar Androgen receptor 4.219e-12 0.34
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.066e-12 0.53
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 5.066e-12 0.53
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.462e-11 0.53
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.274e-11 0.38
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 5.969e-11 0.53
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 5.969e-11 0.53
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 9.149e-11 0.53
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.365e-10 0.38
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.376e-10 0.53
SHH_MOUSE Shh Sonic hedgehog protein 3.63e-10 0.60
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 5.601e-10 0.56
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 8.373e-10 0.53
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.349e-09 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.37e-09 0.30
CP19A_HUMAN CYP19A1 Aromatase 2.019e-09 0.53
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.225e-09 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.152e-09 0.29
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.722e-09 0.66
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 8.109e-09 0.53
GLI1_HUMAN GLI1 Zinc finger protein GLI1 9.718e-09 0.31
DPOLB_RAT Polb DNA polymerase beta 2.644e-08 0.41
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 8.146e-08 0.74
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 9.17e-08 0.32
ANDR_MOUSE Ar Androgen receptor 1.124e-07 0.32
Q690N0_BOVIN PGR Progesterone receptor 1.742e-07 0.32
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.895e-07 0.29
SHH_HUMAN SHH Sonic hedgehog protein 5.577e-07 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 5.849e-07 0.35
RORG_HUMAN RORC Nuclear receptor ROR-gamma 7.332e-07 0.79
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.611e-06 0.29
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 7.896e-06 0.48

compound_3

DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 3.916e-96 0.67
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.376e-82 0.71
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.978e-69 0.56
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.421e-66 0.59
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 1.668e-61 0.48
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.425e-56 0.62
CP125_MYCTU cyp125 Steroid C26-monooxygenase 3.969e-49 0.62
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 1.941e-48 0.65
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 6.387e-48 0.60
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.586e-40 0.54
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.796e-35 0.43
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 2.272e-34 0.56
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 4.654e-34 0.54
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 5.248e-30 0.48
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 7.181e-30 0.30
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.375e-29 0.59
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.532e-26 0.58
ERG2_YEAST ERG2 C-8 sterol isomerase 6.81e-25 0.45
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 6.964e-25 0.33
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 4.199e-23 0.67
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 2.242e-22 0.43
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.832e-20 0.54
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3.931e-20 0.32
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.698e-18 0.29
ECR_DROME EcR Ecdysone receptor 2.22e-16 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 4.441e-16 0.49
ANDR_HUMAN AR Androgen receptor 8.882e-16 0.49
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 1.221e-15 0.30
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 2.653e-14 0.39
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 3.064e-14 0.71
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 3.619e-14 0.29
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 5.684e-14 0.32
SHH_HUMAN SHH Sonic hedgehog protein 5.878e-13 0.33
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.199e-12 0.42
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.337e-12 0.60
REST_BORBU resT Telomere resolvase ResT 3.497e-12 0.30
ANDR_RAT Ar Androgen receptor 4.539e-12 0.34
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.974e-12 0.42
ESR1_HUMAN ESR1 Estrogen receptor 8.361e-12 0.49
ABCBB_HUMAN ABCB11 Bile salt export pump 1.133e-11 0.28
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.335e-11 0.33
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 4.746e-11 0.46
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 8.214e-11 0.46
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.254e-10 0.46
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 2.254e-10 0.46
SHH_MOUSE Shh Sonic hedgehog protein 3.949e-10 0.58
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 5.589e-10 0.46
CP19A_HUMAN CYP19A1 Aromatase 1.573e-09 0.56
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.865e-09 0.46
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.865e-09 0.46
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 2.689e-09 0.46
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.152e-09 0.29
GLI1_HUMAN GLI1 Zinc finger protein GLI1 3.815e-09 0.33
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 3.817e-09 0.46
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.304e-09 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 6.135e-09 0.33
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 8.334e-09 0.54
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.358e-08 0.49
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.794e-08 0.46
ANDR_MOUSE Ar Androgen receptor 1.124e-07 0.32
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.257e-07 0.46
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.698e-07 0.31
Q690N0_BOVIN PGR Progesterone receptor 1.742e-07 0.32
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.835e-07 0.67
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.895e-07 0.29
UD2B7_HUMAN UGT2B7 UDP-glucuronosyltransferase 2B7 6.187e-07 0.28
DPOLB_RAT Polb DNA polymerase beta 7.232e-07 0.33
NR1H4_MOUSE Nr1h4 Bile acid receptor 1.031e-06 0.32
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.611e-06 0.29
HRH3_RAT Hrh3 Histamine H3 receptor 2.948e-06 0.35
IL2_HUMAN IL2 Interleukin-2 6.339e-06 0.31

compound_2

S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 2.241e-51 0.30
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.441e-38 0.36
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.217e-36 0.32
VE2_HPV1 E2 Regulatory protein E2 7.62e-36 0.28
SERPH_HUMAN SERPINH1 Serpin H1 1.734e-23 0.29
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 3.299e-20 0.32
DYR_STAAW folA Dihydrofolate reductase 1.302e-19 0.30
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.195e-17 0.33
B4URF0_I33A0 Neuraminidase 2.22e-15 0.34
REV1_HUMAN REV1 DNA repair protein REV1 7.55e-15 0.29
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 9.504e-14 0.30
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.251e-13 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.932e-11 0.30
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 2.184e-09 0.29
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 4.589e-08 0.28
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 2.041e-07 0.29
Q43570_TOBAC NtBBF1.1 Zn finger protein 4.905e-07 0.29
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 5.181e-07 0.31
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 9.737e-07 0.30
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 2.558e-06 0.29
TLR1_MOUSE Tlr1 Toll-like receptor 1 2.686e-06 0.32
TLR2_MOUSE Tlr2 Toll-like receptor 2 2.686e-06 0.32
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 2.722e-06 0.29
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 6.425e-06 0.30