Results of Job: search_7f10c774-a751-4f5f-a17a-2b3f765f28bf

Query Target Key Target Name Description P-Value MaxTC

compound_1

BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 5.885e-144 0.65
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 4.646e-128 0.85
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 4.227e-110 0.33
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.669e-82 0.38
HSPB1_HUMAN HSPB1 Heat shock protein beta-1 9.765e-50 0.57
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.399e-45 0.57
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 1.72e-41 0.38
PIR_HUMAN PIR Pirin 2.397e-41 0.35
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 8.8e-41 0.35
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 3.915e-39 0.32
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.32e-38 0.36
LCK_HUMAN LCK Tyrosine-protein kinase Lck 9.761e-38 0.44
SRPK1_MOUSE Srpk1 SRSF protein kinase 1 1.007e-35 0.28
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 1.146e-32 0.47
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 1.854e-31 0.33
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 5.739e-31 0.32
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 3.627e-29 0.39
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 5.581e-29 0.37
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 7.368e-28 0.39
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.372e-27 0.41
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 9.348e-27 0.36
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1.522e-26 0.37
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 3.539e-26 0.32
TEC_HUMAN TEC Tyrosine-protein kinase Tec 5.099e-25 0.32
SHH_MOUSE Shh Sonic hedgehog protein 9.746e-25 0.34
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 6.653e-24 0.34
NR2C2_HUMAN NR2C2 Nuclear receptor subfamily 2 group C member 2 3.608e-23 0.28
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 4.429e-22 0.35
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.216e-21 0.37
HSF1_HUMAN HSF1 Heat shock factor protein 1 2.488e-20 0.35
HCK_HUMAN HCK Tyrosine-protein kinase HCK 3.092e-20 0.33
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 3.169e-20 0.32
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 4.761e-20 0.31
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.014e-18 0.41
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.017e-18 0.30
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.044e-18 0.41
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.31e-18 0.41
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 1.983e-18 0.38
TXK_HUMAN TXK Tyrosine-protein kinase TXK 3.052e-18 0.32
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 7.277e-18 0.28
BTK_MOUSE Btk Tyrosine-protein kinase BTK 1.658e-17 0.32
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 4.995e-17 0.37
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 4.441e-16 0.32
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.551e-16 0.38
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 6.661e-16 0.30
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 7.772e-16 0.30
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 7.772e-16 0.31
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 1.887e-15 0.37
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 2.665e-15 0.33
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 4.885e-14 0.33
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 9.015e-14 0.41
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 1.003e-13 0.32
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.605e-13 0.31
YES_HUMAN YES1 Tyrosine-protein kinase Yes 2.703e-13 0.32
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 4.911e-13 0.32
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 9.727e-13 0.31
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.158e-12 0.31
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 1.292e-12 0.38
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 5.496e-12 0.31
ACOD_HUMAN SCD Acyl-CoA desaturase 9.765e-12 0.38
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 1.84e-11 0.35
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 4.507e-11 0.37
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 5.184e-11 0.34
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 8.4e-11 0.32
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.318e-10 0.31
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.519e-10 0.30
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 1.577e-10 0.28
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.983e-10 0.41
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 3.455e-10 0.36
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.206e-10 0.36
INSR_HUMAN INSR Insulin receptor 6.29e-10 0.33
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 7.769e-10 0.36
FRK_HUMAN FRK Tyrosine-protein kinase FRK 1.056e-09 0.33
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 1.624e-09 0.30
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 2.039e-09 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.544e-09 0.36
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 3.737e-09 0.41
NR1H4_HUMAN NR1H4 Bile acid receptor 4.856e-09 0.33
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 5.68e-09 0.38
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 5.982e-09 0.42
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.893e-08 0.43
IDHP_HUMAN IDH2 Isocitrate dehydrogenase [NADP], mitochondrial 2.647e-08 0.31
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 2.678e-08 0.30
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 3.133e-08 0.29
TAAR1_RAT Taar1 Trace amine-associated receptor 1 4.59e-08 0.39
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 6.452e-08 0.33
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 7.179e-08 0.30
IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 7.895e-08 0.33
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.75e-07 0.35
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 1.772e-07 0.33
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 2.245e-07 0.34
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.518e-07 0.39
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 2.725e-07 0.28
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.956e-07 0.31
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 4.056e-07 0.31
HDAC4_HUMAN HDAC4 Histone deacetylase 4 6.743e-07 0.37
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 7.949e-07 0.30
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.104e-06 0.41
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 1.463e-06 0.47
PRIO_SHEEP PRNP Major prion protein 1.959e-06 0.29
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 2.287e-06 0.34
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 3.158e-06 0.30
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 3.621e-06 0.32
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 5.573e-06 0.31
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 5.625e-06 0.35
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 6.159e-06 0.42