Results of Job: search_8067b702-e351-4e23-a008-4daf8641408a

Query Target Key Target Name Description P-Value MaxTC

compound_1

KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 5.303e-156 0.69
AURKA_HUMAN AURKA Aurora kinase A 2.263e-152 0.69
AURKB_HUMAN AURKB Aurora kinase B 9.408e-87 0.58
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.512e-82 0.48
C3SLB7_ECOLX glmU Bifunctional protein GlmU 2.371e-70 0.47
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.125e-59 0.45
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.94e-55 0.45
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 6.985e-53 0.36
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.114e-49 0.39
TPOR_HUMAN MPL Thrombopoietin receptor 5.134e-46 0.36
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 1.437e-42 0.34
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.22e-41 0.39
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 2.46e-41 0.38
BAP1_HUMAN BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1 9.26e-40 0.32
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.468e-39 0.48
PSBA_SPIOL psbA Photosystem II protein D1 1.286e-37 0.33
COX1_SHEEP MT-CO1 Cytochrome c oxidase subunit 1 3.56e-37 0.29
S20A2_HUMAN SLC20A2 Sodium-dependent phosphate transporter 2 1.332e-36 0.29
AURKB_MOUSE Aurkb Aurora kinase B 1.097e-35 0.28
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.278e-35 0.35
LUCI_AQULA Luciferin 4-monooxygenase 8.672e-35 0.38
SHH_MOUSE Shh Sonic hedgehog protein 5.475e-34 0.40
FA10_HUMAN F10 Coagulation factor X 8.009e-34 0.42
PRIO_SHEEP PRNP Major prion protein 1.353e-31 0.42
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.588e-31 0.45
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.716e-30 0.40
F16P1_PIG FBP1 Fructose-1,6-bisphosphatase 1 2.216e-29 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 9.048e-27 0.39
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 1.045e-26 0.33
ENL_HUMAN MLLT1 Protein ENL 1.239e-26 0.33
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.326e-26 0.42
RXFP1_HUMAN RXFP1 Relaxin receptor 1 6.791e-25 0.40
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 9.556e-24 0.43
GBRD_RAT Gabrd Gamma-aminobutyric acid receptor subunit delta 1.348e-23 0.29
S20A1_HUMAN SLC20A1 Sodium-dependent phosphate transporter 1 1.444e-23 0.29
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.466e-23 0.40
AUKBA_XENLA aurkb-a Aurora kinase B-A 6.194e-23 0.37
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 8.182e-23 0.37
Q25615_ONCVO Chitinase 9.276e-23 0.35
DNM3L_HUMAN DNMT3L DNA (cytosine-5)-methyltransferase 3-like 4.933e-22 0.35
WNT3A_MOUSE Wnt3a Protein Wnt-3a 5.932e-22 0.31
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 2.006e-21 0.36
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.048e-21 0.36
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.538e-21 0.35
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 4.523e-21 0.29
Q38C41_TRYB2 Phosphotransferase 2.627e-20 0.30
EPHB_MYCTO Epoxide hydrolase B 3.801e-20 0.32
CD38_MOUSE Cd38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 3.466e-19 0.34
KCNQ2_RAT Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 3.678e-19 0.36
NR1H4_HUMAN NR1H4 Bile acid receptor 2.151e-18 0.35
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 8.087e-18 0.34
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.456e-17 0.34
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.485e-17 0.29
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.546e-17 0.37
APOB_HUMAN APOB Apolipoprotein B-100 2.96e-17 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 4.706e-17 0.31
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.11e-16 0.32
CD38_HUMAN CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1.11e-16 0.34
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.11e-16 0.42
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.11e-16 0.43
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.11e-16 0.41
V1AR_RAT Avpr1a Vasopressin V1a receptor 3.331e-16 0.37
V2R_RAT Avpr2 Vasopressin V2 receptor 8.882e-16 0.37
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.221e-15 0.43
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 4.108e-15 0.29
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.921e-14 0.36
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 2.209e-14 0.34
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.498e-14 0.39
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 3.038e-13 0.39
AURKA_MOUSE Aurka Aurora kinase A 5.641e-13 0.28
MK04_HUMAN MAPK4 Mitogen-activated protein kinase 4 5.848e-13 0.28
TNR16_HUMAN NGFR Tumor necrosis factor receptor superfamily member 16 5.848e-13 0.28
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 6.607e-13 0.32
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 9.427e-13 0.34
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 1.141e-12 0.35
SMO_HUMAN SMO Smoothened homolog 1.572e-12 0.44
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 2.321e-12 0.42
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.47e-12 0.40
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 2.706e-12 0.42
CCNA1_HUMAN CCNA1 Cyclin-A1 3.411e-12 0.32
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 4.224e-12 0.35
BXE_CLOBO botE Botulinum neurotoxin type E 8.017e-12 0.29
BAD_HUMAN BAD Bcl2-associated agonist of cell death 8.469e-12 0.30
ULK3_MOUSE Ulk3 Serine/threonine-protein kinase ULK3 1.383e-11 0.28
CCNK_HUMAN CCNK Cyclin-K 2.618e-11 0.30
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 3.264e-11 0.42
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 3.808e-11 0.34
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 3.935e-11 0.40
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 5.659e-11 0.29
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 7.338e-11 0.30
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.832e-11 0.41
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.481e-10 0.34
O61059_LEIME LmGT2 Glucose transporter 1.68e-10 0.37
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.897e-10 0.38
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 3.28e-10 0.40
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 4.892e-10 0.38
O31272_9GAMM imiS Beta-lactamase 5.219e-10 0.31
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 5.601e-10 0.30
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 7.7e-10 0.38
O97467_PLAFA ht1 Hexose transporter 1 7.83e-10 0.37
SENP7_HUMAN SENP7 Sentrin-specific protease 7 8.023e-10 0.39
PSBA_MARPO psbA Photosystem II protein D1 8.149e-10 0.31
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 8.866e-10 0.34
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.034e-09 0.37
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.267e-09 0.38
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.401e-09 0.38
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.602e-09 0.37
PARP2_MOUSE Parp2 Poly [ADP-ribose] polymerase 2 1.741e-09 0.37
AOFB_RAT Maob Amine oxidase [flavin-containing] B 2.14e-09 0.32
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.196e-09 0.41
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.263e-09 0.31
GBRA6_RAT Gabra6 Gamma-aminobutyric acid receptor subunit alpha-6 2.72e-09 0.29
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 3.243e-09 0.31
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 3.314e-09 0.40
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 3.578e-09 0.30
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 3.808e-09 0.37
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 4.17e-09 0.33
TPA_HUMAN PLAT Tissue-type plasminogen activator 4.752e-09 0.39
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 6.905e-09 0.41
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.158e-08 0.30
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.33e-08 0.33
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.393e-08 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.425e-08 0.28
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 1.425e-08 0.28
TBA1A_RAT Tuba1a Tubulin alpha-1A chain 1.703e-08 0.28
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.834e-08 0.34
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 2.167e-08 0.28
STXA_SHIDY stxA Shiga toxin subunit A 2.572e-08 0.29
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.873e-08 0.32
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 3.716e-08 0.44
EST1_HUMAN CES1 Liver carboxylesterase 1 3.917e-08 0.33
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 4.589e-08 0.29
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 5.028e-08 0.43
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.192e-08 0.28
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 5.651e-08 0.36
CTRO_HUMAN CIT Citron Rho-interacting kinase 7.447e-08 0.30
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 7.808e-08 0.43
CAH4_HUMAN CA4 Carbonic anhydrase 4 7.997e-08 0.38
E3UJZ5_SPOLI Ecdysone receptor 8.415e-08 0.32
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.249e-07 0.41
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 1.291e-07 0.28
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 1.292e-07 0.39
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 1.39e-07 0.37
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.442e-07 0.38
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 1.475e-07 0.35
PTGES_HUMAN PTGES Prostaglandin E synthase 1.634e-07 0.35
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 1.951e-07 0.34
IL6_HUMAN IL6 Interleukin-6 2.362e-07 0.29
BTK_HUMAN BTK Tyrosine-protein kinase BTK 2.387e-07 0.37
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.476e-07 0.38
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 2.577e-07 0.29
GLI1_MOUSE Gli1 Zinc finger protein GLI1 2.582e-07 0.33
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 2.622e-07 0.32
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 2.645e-07 0.28
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 2.723e-07 0.37
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 2.925e-07 0.28
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 3.038e-07 0.38
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 3.123e-07 0.28
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 3.379e-07 0.38
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 3.477e-07 0.29
ACPS_BACSU acpS Holo-[acyl-carrier-protein] synthase 3.513e-07 0.29
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.799e-07 0.30
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 3.902e-07 0.38
KCJ11_HUMAN KCNJ11 ATP-sensitive inward rectifier potassium channel 11 3.995e-07 0.33
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 4.128e-07 0.35
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 4.284e-07 0.29
CYAA_BACAN cya Calmodulin-sensitive adenylate cyclase 4.3e-07 0.33
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 4.339e-07 0.29
EGFR_MOUSE Egfr Epidermal growth factor receptor 4.396e-07 0.29
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 4.396e-07 0.29
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.425e-07 0.45
GATA4_MOUSE Gata4 Transcription factor GATA-4 4.905e-07 0.29
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 4.905e-07 0.29
CNR1_HUMAN CNR1 Cannabinoid receptor 1 4.984e-07 0.33
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 5.092e-07 0.36
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 5.225e-07 0.37
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 5.458e-07 0.31
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 6.013e-07 0.28
GYRB_MYCS2 gyrB DNA gyrase subunit B 6.257e-07 0.29
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 6.751e-07 0.28
UREA_CANEN Urease 6.795e-07 0.33
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 6.958e-07 0.30
DNM3B_HUMAN DNMT3B DNA (cytosine-5)-methyltransferase 3B 7.411e-07 0.35
Q6QLK5_9HIV1 env Envelope glycoprotein gp160 8.467e-07 0.35
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 8.554e-07 0.32
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 8.715e-07 0.33
HDAC6_HUMAN HDAC6 Histone deacetylase 6 8.998e-07 0.36
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.161e-06 0.38
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 1.218e-06 0.36
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 1.294e-06 0.34
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 1.301e-06 0.42
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.331e-06 0.29
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 1.393e-06 0.32
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.672e-06 0.38
EST1_RABIT Liver carboxylesterase 1 1.812e-06 0.29
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.943e-06 0.31
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 2.031e-06 0.34
UROK_HUMAN PLAU Urokinase-type plasminogen activator 2.053e-06 0.39
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.697e-06 0.41
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 2.97e-06 0.31
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 3.057e-06 0.30
Q8MWR1_SPOFR USP Ultraspiracle protein 3.07e-06 0.32
Q8MWR2_SPOFR EcR Ecdysteroid receptor 3.07e-06 0.32
STRP_STRP1 ska Streptokinase A 3.095e-06 0.38
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 3.328e-06 0.38
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 3.409e-06 0.28
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 4.107e-06 0.31
LYOX_HUMAN LOX Protein-lysine 6-oxidase 4.184e-06 0.30
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 4.74e-06 0.31
ECR_BOMMO EcR Ecdysone receptor 4.786e-06 0.32
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 5.034e-06 0.28
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 5.463e-06 0.28
Q76129_9HIV1 gag Structural capsid protein 5.879e-06 0.29
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 5.939e-06 0.28
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 5.974e-06 0.36
TRPA1_HUMAN TRPA1 Transient receptor potential cation channel subfamily A member 1 6.368e-06 0.32
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 6.699e-06 0.33
GABT_RAT Abat 4-aminobutyrate aminotransferase, mitochondrial 6.867e-06 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 7.631e-06 0.37
FRK_HUMAN FRK Tyrosine-protein kinase FRK 7.866e-06 0.38
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 8.017e-06 0.37
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 8.068e-06 0.43
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 8.075e-06 0.36
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 8.145e-06 0.38
GBRA4_RAT Gabra4 Gamma-aminobutyric acid receptor subunit alpha-4 8.994e-06 0.29
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 8.997e-06 0.38