Results of Job: search_84b10118-d23e-46b7-9fcd-9cdb8a01eb42

Query Target Key Target Name Description P-Value MaxTC

Brensocatib

CATC_HUMAN CTSC Dipeptidyl peptidase 1 2.133e-304 1.00
CATC_CANLF CTSC Dipeptidyl peptidase 1 2.9e-124 1.00
CATC_MOUSE Ctsc Dipeptidyl peptidase 1 2.9e-124 1.00
CATC_RAT Ctsc Dipeptidyl peptidase 1 1.089e-50 1.00
LGMN_HUMAN LGMN Legumain 5.187e-74 0.32
CATF_HUMAN CTSF Cathepsin F 7.689e-45 0.32
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 6.304e-11 0.29
CYSP_TRYCR Cruzipain 6.145e-10 0.32
CATK_HUMAN CTSK Cathepsin K 2.123e-09 0.46
TSPO_RAT Tspo Translocator protein 7.904e-09 0.32
ASAH1_HUMAN ASAH1 Acid ceramidase 8.435e-08 0.34
CATH_HUMAN CTSH Pro-cathepsin H 4.203e-07 0.38

Maralixibat

NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 4.799e-230 1.00
ADA17_RAT Adam17 Disintegrin and metalloproteinase domain-containing protein 17 4.283e-12 0.33

Zuranolone

GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 6.753e-207 1.00
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 8.126e-83 1.00
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 5.056e-57 1.00
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.296e-23 1.00
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 2.108e-20 1.00
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 1.581e-17 1.00
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 8.558e-41 0.36
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.66e-40 0.37
ANDR_RAT Ar Androgen receptor 2.291e-24 0.33
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.373e-22 0.36
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 1.941e-20 0.31
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.895e-18 0.31
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.937e-12 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.54e-12 0.31
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.071e-10 0.36
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.946e-09 0.36
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.608e-09 0.28
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.406e-08 0.31
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.537e-07 0.31
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 2.507e-07 0.30
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 1.243e-06 0.31
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.964e-06 0.29

Ubrogepant

RAMP1_HUMAN RAMP1 Receptor activity-modifying protein 1 2.935e-183 1.00
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 3.7e-98 1.00
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 4.181e-84 0.46
CALCR_HUMAN CALCR Calcitonin receptor 1.579e-56 0.45
CALRL_MOUSE Calcrl Calcitonin gene-related peptide type 1 receptor 1.579e-56 0.45
RAMP3_HUMAN RAMP3 Receptor activity-modifying protein 3 1.579e-56 0.45
CALCA_HUMAN CALCA Calcitonin gene-related peptide 1 8.082e-31 0.41
IL6_HUMAN IL6 Interleukin-6 2.87e-21 0.31
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.67e-12 0.32
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 3.643e-09 0.32
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.797e-06 0.30

Atogepant

RAMP1_HUMAN RAMP1 Receptor activity-modifying protein 1 3.562e-181 1.00
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 1.226e-99 1.00
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 3.31e-83 0.45
CALCR_HUMAN CALCR Calcitonin receptor 1.208e-56 0.45
CALRL_MOUSE Calcrl Calcitonin gene-related peptide type 1 receptor 1.208e-56 0.45
RAMP3_HUMAN RAMP3 Receptor activity-modifying protein 3 1.208e-56 0.45
CALCA_HUMAN CALCA Calcitonin gene-related peptide 1 4.462e-30 0.39
CALCA_RAT Calca Calcitonin gene-related peptide 1 1.444e-23 0.29

Cedazuridine

CDD_HUMAN CDA Cytidine deaminase 1.043e-164 1.00
CDD_MOUSE Cda Cytidine deaminase 6.984e-72 0.58
A3RLP8_CHV1 UL23 Thymidine kinase 2.652e-42 0.31
KITH_HHV1 TK Thymidine kinase 1.99e-17 0.49
KITH_HUMAN TK1 Thymidine kinase, cytosolic 3.353e-13 0.30
Q03732_HBV HBcAg Capsid protein 7.679e-06 0.30

Danicopan

CFAD_HUMAN CFD Complement factor D 2.356e-149 1.00

Zavegepant

CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 2.432e-137 1.00
CALCA_HUMAN CALCA Calcitonin gene-related peptide 1 1.167e-158 0.54
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 2.663e-53 0.40
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 2.073e-40 0.40
CALRL_RAT Calcrl Calcitonin gene-related peptide type 1 receptor 7.96e-29 0.37
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 3.054e-26 0.33
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 5.066e-20 0.32
IGF1R_MOUSE Igf1r Insulin-like growth factor 1 receptor 8.995e-19 0.32
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 5.081e-17 0.35
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 3.193e-12 0.33
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 2.252e-11 0.31
PLD1_RAT Pld1 Phospholipase D1 6.825e-11 0.28
JUN_HUMAN JUN Transcription factor AP-1 4.037e-10 0.32
MC4R_HUMAN MC4R Melanocortin receptor 4 6.63e-10 0.35
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 2.331e-09 0.33
PLD2_HUMAN PLD2 Phospholipase D2 8.442e-08 0.31
ATAD2_HUMAN ATAD2 ATPase family AAA domain-containing protein 2 1.165e-06 0.30
CEGT_HUMAN UGCG Ceramide glucosyltransferase 1.198e-06 0.30
BKRB1_RAT Bdkrb1 B1 bradykinin receptor 1.37e-06 0.31
MC3R_HUMAN MC3R Melanocortin receptor 3 1.371e-06 0.35
PEPT1_DERPT DERP1 Peptidase 1 1.988e-06 0.29
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.047e-06 0.28
RAMP1_HUMAN RAMP1 Receptor activity-modifying protein 1 3.117e-06 0.43

Vorasidenib

IDHP_HUMAN IDH2 Isocitrate dehydrogenase [NADP], mitochondrial 2.772e-121 1.00
IDHC_HUMAN IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 6.848e-12 1.00
KCNH3_HUMAN KCNH3 Potassium voltage-gated channel subfamily H member 3 1.92e-21 0.33
PETD_SPIOL petD Cytochrome b6-f complex subunit 4 2.323e-06 0.30

Rilzabrutinib

BTK_HUMAN BTK Tyrosine-protein kinase BTK 9.159e-118 1.00
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 7.505e-12 1.00
PXL2A_HUMAN PRXL2A Peroxiredoxin-like 2A 1.972e-66 0.53
HCK_HUMAN HCK Tyrosine-protein kinase HCK 7.057e-50 0.53
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 5.002e-35 0.53
LCK_HUMAN LCK Tyrosine-protein kinase Lck 3.589e-32 0.53
TIE2_HUMAN TEK Angiopoietin-1 receptor 2.937e-24 0.43
TEC_HUMAN TEC Tyrosine-protein kinase Tec 2.331e-22 0.53
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.529e-22 0.53
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 3.863e-21 0.35
EGFR_HUMAN EGFR Epidermal growth factor receptor 1.772e-20 0.53
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 1.296e-18 0.35
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 4.321e-18 0.35
CDPK4_PLAF7 CPK4 Calcium-dependent protein kinase 4 7.277e-18 0.28
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.957e-17 0.53
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 7.772e-16 0.56
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 1.998e-15 0.35
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.078e-13 0.35
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.4e-13 0.53
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 3.289e-12 0.35
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 3.922e-12 0.53
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 4.291e-12 0.53
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 4.258e-11 0.35
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 8.157e-10 0.53
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.12e-09 0.53
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 4.359e-09 0.35
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 7.846e-09 0.33
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 8.679e-09 0.53
FER_HUMAN FER Tyrosine-protein kinase Fer 4.103e-08 0.53
INSR_MOUSE Insr Insulin receptor 5.39e-08 0.30
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 8.752e-08 0.53
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 1.485e-07 0.53
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.562e-07 0.53
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 3.169e-07 0.35
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 4.46e-07 0.33
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 6.758e-07 0.43
KCC1A_HUMAN CAMK1 Calcium/calmodulin-dependent protein kinase type 1 7.961e-07 0.35
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 8.975e-07 0.53
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 4.652e-06 0.35
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 5.054e-06 0.35

Delgocitinib

JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 5.992e-110 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 2.083e-70 1.00
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 1.798e-74 0.55
JAK3_RAT Jak3 Tyrosine-protein kinase JAK3 4.15e-60 0.48
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.59e-52 0.48
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 1.102e-43 0.47
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 6.045e-34 0.46
LIMK2_HUMAN LIMK2 LIM domain kinase 2 7.112e-25 0.44
MP2K7_HUMAN MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 2.046e-22 0.31
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 4.138e-21 0.46
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 3.592e-19 0.48
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.11e-16 0.48
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 5.551e-16 0.48
VRK2_HUMAN VRK2 Serine/threonine-protein kinase VRK2 4.03e-14 0.31
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 6.725e-13 0.48
DMPK_HUMAN DMPK Myotonin-protein kinase 1.421e-12 0.48
DCLK3_HUMAN DCLK3 Serine/threonine-protein kinase DCLK3 5.522e-12 0.48
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 1.78e-11 0.31
GRK7_HUMAN GRK7 Rhodopsin kinase GRK7 1.837e-11 0.48
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 5.374e-11 0.48
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 5.374e-11 0.48
NUAK2_HUMAN NUAK2 NUAK family SNF1-like kinase 2 1.411e-10 0.48
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 5.024e-10 0.48
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 7.642e-10 0.31
DOT1L_HUMAN DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.651e-09 0.31
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 2.29e-08 0.43
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 2.442e-08 0.48
ATR_HUMAN ATR Serine/threonine-protein kinase ATR 2.64e-08 0.30
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 2.856e-08 0.31
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 2.856e-08 0.31
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 2.856e-08 0.31
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 2.856e-08 0.31
LIMK1_HUMAN LIMK1 LIM domain kinase 1 4.155e-08 0.44
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 4.362e-08 0.48
STK26_HUMAN STK26 Serine/threonine-protein kinase 26 5.984e-08 0.31
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 6.985e-08 0.31
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 1.537e-07 0.31
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 1.537e-07 0.31
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 1.537e-07 0.31
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 2.109e-07 0.48
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 2.109e-07 0.48
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 3.098e-07 0.31
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.025e-06 0.31
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.025e-06 0.31
M4K3_HUMAN MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 1.056e-06 0.48
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 1.209e-06 0.48
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 1.209e-06 0.48
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 1.717e-06 0.31
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.717e-06 0.31
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 1.808e-06 0.48
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 2.951e-06 0.48
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 9.117e-06 0.31
PAK5_HUMAN PAK5 Serine/threonine-protein kinase PAK 5 9.117e-06 0.31

Leniolisib

PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.221e-105 1.00
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 9.595e-36 1.00
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.035e-23 1.00
PK3CG_MOUSE Pik3cg Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2.387e-14 1.00
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.756e-05 1.00
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0.0565 1.00
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 0.06561 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.4773 1.00
P2RX2_HUMAN P2RX2 P2X purinoceptor 2 4.231e-51 0.34
P2RX3_HUMAN P2RX3 P2X purinoceptor 3 1.27e-21 0.34
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.519e-21 0.36
FAK1_HUMAN PTK2 Focal adhesion kinase 1 4.758e-21 0.32
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.11e-15 0.35
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.776e-15 0.32
MTOR_MOUSE Mtor Serine/threonine-protein kinase mTOR 6.45e-14 0.32
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.116e-13 0.35
CCR2_RAT Ccr2 C-C chemokine receptor type 2 9.7e-12 0.29
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 1.216e-11 0.32
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 8.899e-11 0.33
PB2_I34A1 PB2 Polymerase basic protein 2 2.757e-09 0.36
P3C2A_HUMAN PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 4.408e-08 0.32
ACOD_HUMAN SCD Acyl-CoA desaturase 7.359e-08 0.32
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.669e-07 0.37
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 3.5e-07 0.31
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 3.999e-07 0.30
CCRL2_HUMAN CCRL2 C-C chemokine receptor-like 2 5.01e-07 0.29
SFRP1_HUMAN SFRP1 Secreted frizzled-related protein 1 5.444e-07 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.022e-06 0.36
RET4_HUMAN RBP4 Retinol-binding protein 4 1.592e-06 0.31
PB1_HUMAN PBRM1 Protein polybromo-1 2.153e-06 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 4.546e-06 0.35

Xanomeline

ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 8.028e-92 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 5.898e-44 1.00
Q8WMX0_BOVIN Muscarinic receptor M1 9.345e-31 0.50
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 5.153e-24 0.90
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 4.247e-22 0.90
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.68e-13 0.90
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.847e-11 0.90
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 3.046e-09 0.50
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 4.644e-09 0.58
CHLE_HORSE BCHE Cholinesterase 8.077e-08 0.51

Fezolinetant

NK3R_HUMAN TACR3 Neuromedin-K receptor 1.343e-74 1.00
NK3R_RAT Tacr3 Neuromedin-K receptor 6.646e-64 1.00
Q2WGM0_MACMU nk-3 NK-3 receptor 2.672e-118 0.73
FABP5_HUMAN FABP5 Fatty acid-binding protein 5 4.33e-14 0.29
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 2.195e-12 0.31
P2RX7_RAT P2rx7 P2X purinoceptor 7 1.539e-10 0.48
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 2.98e-08 0.32
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 4.178e-07 0.29
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 7.823e-06 0.29

Chlormadinone_acetate

Q690N0_BOVIN PGR Progesterone receptor 2.678e-73 1.00
ANDR_RAT Ar Androgen receptor 2.251e-22 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 5.391e-08 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.2443 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.433e-46 0.40
SHBG_HUMAN SHBG Sex hormone-binding globulin 7.217e-34 0.58
CP19A_HUMAN CYP19A1 Aromatase 2.424e-24 0.44
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1.707e-22 0.32
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.122e-19 0.31
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.523e-18 0.29
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.332e-15 0.34
GCR_MOUSE Nr3c1 Glucocorticoid receptor 3.664e-15 0.31
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.43e-14 0.31
PRGR_RAT Pgr Progesterone receptor 1.446e-13 0.30
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3.136e-13 0.32
ANDR_MOUSE Ar Androgen receptor 1.145e-12 0.58
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 8.853e-11 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.035e-10 0.34
PRGR_RABIT PGR Progesterone receptor 1.085e-09 0.34
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.197e-09 0.37
ERG2_YEAST ERG2 C-8 sterol isomerase 1.527e-08 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.739e-07 0.34
ANDR_HUMAN AR Androgen receptor 8.199e-07 0.66
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.24e-06 0.32
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 4.848e-06 0.58

Trilaciclib

CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 3.777e-58 1.00
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 7.906e-241 0.50
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 1.697e-190 0.48
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 4.541e-165 0.50
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 3.356e-136 0.42
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 7.719e-103 0.46
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 5.175e-55 0.38
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 4.026e-54 0.43
CCNA2_HUMAN CCNA2 Cyclin-A2 3.175e-44 0.50
CCNH_HUMAN CCNH Cyclin-H 8.107e-43 0.42
INSR_RAT Insr Insulin receptor 8.972e-38 0.30
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 2.943e-35 0.47
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 3.731e-34 0.43
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 2.807e-32 0.31
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 6.217e-23 0.42
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 8.667e-23 0.38
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 8.687e-23 0.43
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 8.687e-23 0.43
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.002e-22 0.41
CCNA1_HUMAN CCNA1 Cyclin-A1 2.052e-20 0.43
ST32C_HUMAN STK32C Serine/threonine-protein kinase 32C 7.776e-19 0.30
CCNT1_HUMAN CCNT1 Cyclin-T1 1.161e-18 0.46
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 9.583e-18 0.34
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 4.595e-17 0.33
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 1.11e-16 0.37
TTK_HUMAN TTK Dual specificity protein kinase TTK 1.11e-16 0.39
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 4.441e-16 0.36
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 5.551e-16 0.36
SRC_MOUSE Src Neuronal proto-oncogene tyrosine-protein kinase Src 1.554e-15 0.30
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 3.442e-15 0.42
INSR_HUMAN INSR Insulin receptor 7.327e-15 0.41
SNRK_HUMAN SNRK SNF-related serine/threonine-protein kinase 1.052e-13 0.30
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 1.392e-13 0.43
WEE2_HUMAN WEE2 Wee1-like protein kinase 2 1.518e-13 0.31
BTK_MOUSE Btk Tyrosine-protein kinase BTK 3.908e-13 0.33
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 1.039e-12 0.30
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.545e-12 0.36
ALK_MOUSE Alk ALK tyrosine kinase receptor 3.019e-12 0.30
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 3.019e-12 0.30
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 4.916e-12 0.31
WEE1_HUMAN WEE1 Wee1-like protein kinase 4.954e-12 0.36
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.698e-11 0.46
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 3.163e-11 0.41
NEK3_HUMAN NEK3 Serine/threonine-protein kinase Nek3 3.845e-11 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 7.27e-11 0.38
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 8.715e-11 0.43
FAK1_HUMAN PTK2 Focal adhesion kinase 1 2.227e-10 0.33
HSF1_HUMAN HSF1 Heat shock factor protein 1 3.137e-10 0.37
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 5.512e-10 0.39
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 5.718e-10 0.36
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 1.062e-09 0.40
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 1.276e-09 0.35
M3K15_HUMAN MAP3K15 Mitogen-activated protein kinase kinase kinase 15 1.469e-09 0.30
STK38_HUMAN STK38 Serine/threonine-protein kinase 38 1.469e-09 0.30
SRC_CHICK SRC Proto-oncogene tyrosine-protein kinase Src 3.737e-09 0.40
AURKA_HUMAN AURKA Aurora kinase A 4.808e-09 0.41
LCK_HUMAN LCK Tyrosine-protein kinase Lck 5.401e-09 0.33
AVR2A_HUMAN ACVR2A Activin receptor type-2A 5.728e-09 0.30
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 5.728e-09 0.30
ST32B_HUMAN STK32B Serine/threonine-protein kinase 32B 5.728e-09 0.30
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 5.728e-09 0.30
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 6.195e-09 0.41
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 1.009e-08 0.35
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 1.149e-08 0.38
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.624e-08 0.38
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 1.817e-08 0.30
NUAK1_HUMAN NUAK1 NUAK family SNF1-like kinase 1 2.339e-08 0.42
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 3.601e-08 0.32
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 4.908e-08 0.30
CSKP_HUMAN CASK Peripheral plasma membrane protein CASK 4.908e-08 0.30
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 4.908e-08 0.30
MAST1_HUMAN MAST1 Microtubule-associated serine/threonine-protein kinase 1 4.908e-08 0.30
MYO3A_HUMAN MYO3A Myosin-IIIa 4.908e-08 0.30
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 4.908e-08 0.30
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 4.908e-08 0.30
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 6.454e-08 0.35
TEC_HUMAN TEC Tyrosine-protein kinase Tec 7.312e-08 0.31
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 1.11e-07 0.31
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 1.168e-07 0.30
MRCKB_HUMAN CDC42BPB Serine/threonine-protein kinase MRCK beta 1.168e-07 0.30
MRCKG_HUMAN CDC42BPG Serine/threonine-protein kinase MRCK gamma 1.168e-07 0.30
MYO3B_HUMAN MYO3B Myosin-IIIb 1.168e-07 0.30
ST32A_HUMAN STK32A Serine/threonine-protein kinase 32A 1.168e-07 0.30
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 2.507e-07 0.30
NEK7_HUMAN NEK7 Serine/threonine-protein kinase Nek7 2.507e-07 0.30
SBK3_HUMAN SBK3 Uncharacterized serine/threonine-protein kinase SBK3 2.507e-07 0.30
SIK3_HUMAN SIK3 Serine/threonine-protein kinase SIK3 2.507e-07 0.30
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 4.549e-07 0.38
HUNK_HUMAN HUNK Hormonally up-regulated neu tumor-associated kinase 4.948e-07 0.30
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 4.948e-07 0.30
NIM1_HUMAN NIM1K Serine/threonine-protein kinase NIM1 4.948e-07 0.30
PRP4B_HUMAN PRPF4B Serine/threonine-protein kinase PRP4 homolog 4.948e-07 0.30
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 9.101e-07 0.30
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 9.101e-07 0.30
AVR2B_HUMAN ACVR2B Activin receptor type-2B 1.578e-06 0.30
KCC1G_HUMAN CAMK1G Calcium/calmodulin-dependent protein kinase type 1G 1.578e-06 0.30
SBK1_HUMAN SBK1 Serine/threonine-protein kinase SBK1 1.578e-06 0.30
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.578e-06 0.30
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 1.619e-06 0.41
AURKB_HUMAN AURKB Aurora kinase B 1.737e-06 0.36
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 2.601e-06 0.30
PAK6_HUMAN PAK6 Serine/threonine-protein kinase PAK 6 2.601e-06 0.30
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 2.601e-06 0.30
PRIO_SHEEP PRNP Major prion protein 2.849e-06 0.29
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 4.105e-06 0.30
INSRR_HUMAN INSRR Insulin receptor-related protein 4.105e-06 0.30
M3K4_HUMAN MAP3K4 Mitogen-activated protein kinase kinase kinase 4 4.105e-06 0.30
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 6.241e-06 0.30
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 6.241e-06 0.30
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 6.241e-06 0.30
O97467_PLAFA ht1 Hexose transporter 1 7.616e-06 0.35
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 9.182e-06 0.30
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 9.182e-06 0.30
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 9.182e-06 0.30

Belumosudil

ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.569e-55 1.00
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.581e-36 1.00
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 2.884e-24 1.00
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 2.349e-23 1.00
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 3.28e-20 1.00
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 7.352e-20 1.00
AURKB_HUMAN AURKB Aurora kinase B 1.517e-19 1.00
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 3.331e-16 1.00
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 5.329e-15 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 6.711e-12 1.00
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.065e-101 0.46
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 6.966e-53 0.41
GDIR1_HUMAN ARHGDIA Rho GDP-dissociation inhibitor 1 6.552e-48 0.35
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 6.353e-33 0.41
CDK3_HUMAN CDK3 Cyclin-dependent kinase 3 8.412e-31 0.33
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 1.252e-29 0.34
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 1.027e-27 0.55
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.109e-25 0.41
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 1.113e-24 0.47
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 2.334e-24 0.42
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 3.477e-23 0.31
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.023e-23 0.32
WDR48_HUMAN WDR48 WD repeat-containing protein 48 5.227e-23 0.31
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 6.794e-23 0.28
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 9.642e-23 0.34
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.352e-22 0.31
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 1.31e-21 0.38
MRCKA_HUMAN CDC42BPA Serine/threonine-protein kinase MRCK alpha 1.359e-21 0.55
PKNB_MYCTU pknB Serine/threonine-protein kinase PknB 2.065e-21 0.37
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.205e-21 0.31
LCK_MOUSE Lck Proto-oncogene tyrosine-protein kinase LCK 3.889e-21 0.41
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 4.091e-21 0.55
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 1.341e-20 0.41
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.713e-20 0.46
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 7.008e-20 0.55
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 7.081e-20 0.57
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 5.785e-19 0.41
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 6.291e-19 0.41
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 1.08e-18 0.41
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.791e-18 0.36
AURKA_HUMAN AURKA Aurora kinase A 2.092e-18 0.40
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 2.811e-18 0.40
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 3.669e-18 0.55
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 6.273e-18 0.40
CMA1_RAT Cma1 Chymase 7.088e-18 0.28
MCPT9_MOUSE Mcpt9 Mast cell protease 9 7.088e-18 0.28
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 7.671e-18 0.41
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 1.459e-17 0.41
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 1.711e-17 0.38
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 3.167e-17 0.41
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 1.11e-16 0.55
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.11e-16 0.35
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 5.551e-16 0.30
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.992e-16 0.46
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 1.11e-15 0.30
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.221e-15 0.31
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 2.22e-15 0.41
KPCG_HUMAN PRKCG Protein kinase C gamma type 2.442e-15 0.55
CASP1_MOUSE Casp1 Caspase-1 3.109e-15 0.34
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 3.997e-15 0.41
MK12_HUMAN MAPK12 Mitogen-activated protein kinase 12 3.997e-15 0.41
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 4.663e-15 0.34
Q76129_9HIV1 gag Structural capsid protein 1.066e-14 0.40
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 2.143e-14 0.38
NK3R_HUMAN TACR3 Neuromedin-K receptor 2.942e-14 0.34
CHLE_HORSE BCHE Cholinesterase 2.998e-14 0.32
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 3.275e-14 0.36
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 3.331e-14 0.41
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 4.752e-14 0.41
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 4.785e-14 0.41
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 1.547e-13 0.38
PDE5A_HUMAN PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 1.896e-13 0.46
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 2.229e-13 0.55
KC1G3_HUMAN CSNK1G3 Casein kinase I isoform gamma-3 2.27e-13 0.41
CASP8_HUMAN CASP8 Caspase-8 2.854e-13 0.36
AKT3_HUMAN AKT3 RAC-gamma serine/threonine-protein kinase 4.804e-13 0.55
KCC2G_HUMAN CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 5.11e-13 0.55
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 5.718e-13 0.41
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 6.529e-13 0.55
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 9.167e-13 0.31
MK13_HUMAN MAPK13 Mitogen-activated protein kinase 13 9.7e-13 0.41
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1.162e-12 0.55
KS6A1_HUMAN RPS6KA1 Ribosomal protein S6 kinase alpha-1 2.775e-12 0.39
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 5.345e-12 0.55
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 6.407e-12 0.41
ARBK1_BOVIN GRK2 Beta-adrenergic receptor kinase 1 7.203e-12 0.31
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 8.927e-12 0.41
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 9.339e-12 0.55
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 9.891e-12 0.55
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 1.343e-11 0.55
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 1.983e-11 0.41
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 2.401e-11 0.35
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 2.401e-11 0.33
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 2.466e-11 0.41
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.736e-11 0.41
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 2.945e-11 0.45
VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 3.882e-11 0.30
EGFR_HUMAN EGFR Epidermal growth factor receptor 4.393e-11 0.46
PTK6_HUMAN PTK6 Protein-tyrosine kinase 6 5.287e-11 0.34
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 5.479e-11 0.39
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 5.678e-11 0.55
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 7.096e-11 0.37
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 7.296e-11 0.31
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 8.302e-11 0.55
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 1.076e-10 0.41
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 1.22e-10 0.33
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.226e-10 0.37
ACES_ELEEL ache Acetylcholinesterase 1.341e-10 0.32
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.444e-10 0.37
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 2.432e-10 0.55
KPCD_HUMAN PRKCD Protein kinase C delta type 2.601e-10 0.55
NR1H2_MOUSE Nr1h2 Oxysterols receptor LXR-beta 3.382e-10 0.30
TOPK_HUMAN PBK Lymphokine-activated killer T-cell-originated protein kinase 4.098e-10 0.55
V1BR_RAT Avpr1b Vasopressin V1b receptor 4.104e-10 0.35
SHH_MOUSE Shh Sonic hedgehog protein 4.939e-10 0.35
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 5.012e-10 0.32
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 7.107e-10 0.33
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 8.287e-10 0.37
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 9.035e-10 0.33
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 9.746e-10 0.41
MATK_HUMAN MATK Megakaryocyte-associated tyrosine-protein kinase 1.2e-09 0.34
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.297e-09 0.46
PKN1_HUMAN PKN1 Serine/threonine-protein kinase N1 1.444e-09 0.39
FRK_HUMAN FRK Tyrosine-protein kinase FRK 1.591e-09 0.41
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.7e-09 0.41
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 1.816e-09 0.41
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 3.44e-09 0.41
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 4.377e-09 0.43
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 6.59e-09 0.41
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 6.653e-09 0.41
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.058e-08 0.36
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.141e-08 0.31
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 1.976e-08 0.41
ACVR1_HUMAN ACVR1 Activin receptor type-1 2.822e-08 0.55
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.913e-08 0.34
ESR1_HUMAN ESR1 Estrogen receptor 3.071e-08 0.35
CASP3_HUMAN CASP3 Caspase-3 3.997e-08 0.36
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 4.04e-08 0.43
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 4.798e-08 0.30
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 5.416e-08 0.33
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 5.851e-08 0.41
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 6.596e-08 0.32
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 8.777e-08 0.55
WEE1_HUMAN WEE1 Wee1-like protein kinase 8.974e-08 0.34
MTNN_ECOLI mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 9.503e-08 0.33
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.047e-07 0.37
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1.076e-07 0.44
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 1.077e-07 0.41
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 2.094e-07 0.56
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 2.125e-07 0.33
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.17e-07 0.39
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 2.191e-07 0.41
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 2.507e-07 0.34
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 2.77e-07 0.41
RON_HUMAN MST1R Macrophage-stimulating protein receptor 3.038e-07 0.55
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 3.521e-07 0.41
LIMK1_HUMAN LIMK1 LIM domain kinase 1 3.649e-07 0.34
CBPA1_HUMAN CPA1 Carboxypeptidase A1 3.757e-07 0.29
CASP7_HUMAN CASP7 Caspase-7 4.158e-07 0.36
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 4.324e-07 0.29
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 4.443e-07 0.34
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 4.902e-07 0.41
SYT_YERPE thrS Threonine--tRNA ligase 5.919e-07 0.35
KCC1D_HUMAN CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 6.096e-07 0.34
FER_HUMAN FER Tyrosine-protein kinase Fer 6.642e-07 0.41
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 7.138e-07 0.41
MTAP2_HUMAN MAP2 Microtubule-associated protein 2 7.672e-07 0.29
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 8.036e-07 0.35
CASP1_HUMAN CASP1 Caspase-1 8.554e-07 0.36
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 8.674e-07 0.41
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 9.994e-07 0.41
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 1.755e-06 0.31
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 2.131e-06 0.35
PTN13_HUMAN PTPN13 Tyrosine-protein phosphatase non-receptor type 13 2.648e-06 0.29
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 2.848e-06 0.33
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 2.876e-06 0.41
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 2.951e-06 0.32
F16P1_RAT Fbp1 Fructose-1,6-bisphosphatase 1 4.145e-06 0.30
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 4.894e-06 0.34
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.073e-06 0.41
CYSP_TRYCR Cruzipain 5.153e-06 0.35
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 5.581e-06 0.37
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 6.096e-06 0.33
KPCT_HUMAN PRKCQ Protein kinase C theta type 6.194e-06 0.55
TXK_HUMAN TXK Tyrosine-protein kinase TXK 6.317e-06 0.33
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 7.191e-06 0.55
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 7.496e-06 0.34
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 8.09e-06 0.28
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 8.587e-06 0.41
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 8.599e-06 0.34
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 9.647e-06 0.29

Colchiceine

TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.674e-32 1.00
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 2.097e-101 0.85
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.433e-81 0.85
TBB5_HUMAN TUBB Tubulin beta chain 1.871e-67 0.85
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 1.871e-67 0.85
MTR1B_CHICK Melatonin receptor type 1B 1.198e-34 0.37
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 1.313e-27 0.53
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.514e-17 0.85
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 3.196e-13 0.37
CP27A_HUMAN CYP27A1 Sterol 26-hydroxylase, mitochondrial 5.848e-13 0.28
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 1.418e-12 0.85
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 5.452e-12 0.37
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 9.7e-12 0.29
SC6A9_BOVIN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 9.862e-12 0.29
CP24A_RAT Cyp24a1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.383e-11 0.28
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 2.063e-09 0.32
MTSI_SPISQ sssIM CPG DNA methylase 3.598e-09 0.29
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 3.378e-08 0.36
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 1.185e-07 0.30
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 1.195e-07 0.32
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 1.256e-07 0.32
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 1.636e-07 0.32
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.362e-07 0.29
GLMU_ECOLI glmU Bifunctional protein GlmU 2.79e-07 0.30
PAX8_HUMAN PAX8 Paired box protein Pax-8 5.3e-07 0.85
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 5.71e-07 0.32
SHBG_HUMAN SHBG Sex hormone-binding globulin 7.332e-07 0.31
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 7.696e-07 0.32
TYRO_HUMAN TYR Tyrosinase 1.373e-06 0.31
LGUL_HUMAN GLO1 Lactoylglutathione lyase 2.26e-06 0.29
CDK3_HUMAN CDK3 Cyclin-dependent kinase 3 2.543e-06 0.32
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 4.151e-06 0.30
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 7.929e-06 0.32
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 8.365e-06 0.30
DRD1_HUMAN DRD1 D(1A) dopamine receptor 9.973e-06 0.31

Finerenone

MCR_HUMAN NR3C2 Mineralocorticoid receptor 2.22e-16 1.00
FAS_HUMAN FASN Fatty acid synthase 4.365e-37 0.38
PRKDC_HUMAN PRKDC DNA-dependent protein kinase catalytic subunit 8.137e-27 0.37
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.112e-20 0.29
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 2.331e-15 0.37
CFAB_HUMAN CFB Complement factor B 2.32e-14 0.29
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 4.735e-13 0.32
RS27_HUMAN RPS27 40S ribosomal protein S27 4.965e-12 0.32
TDT_HUMAN DNTT DNA nucleotidylexotransferase 5.251e-12 0.29
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 6.416e-12 0.37
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 8.017e-12 0.29
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.836e-11 0.31
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 1.742e-10 0.32
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 1.377e-09 0.31
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 2.86e-08 0.33
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 7.315e-08 0.32
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.498e-07 0.33
KS6B2_HUMAN RPS6KB2 Ribosomal protein S6 kinase beta-2 2.06e-07 0.32
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.933e-06 0.37
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.448e-06 0.30

Domatinostat

HDAC3_HUMAN HDAC3 Histone deacetylase 3 3.331e-16 1.00
CCNC_HUMAN CCNC Cyclin-C 1.67e-41 0.40
HDAC1_HUMAN HDAC1 Histone deacetylase 1 4.784e-32 0.51
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 4.036e-27 0.40
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 1.402e-24 0.41
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.044e-14 0.38
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 1.446e-13 0.30
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 2.186e-12 0.30
STXA_SHIDY stxA Shiga toxin subunit A 2.37e-09 0.33
FER_HUMAN FER Tyrosine-protein kinase Fer 3.573e-09 0.35
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 4.919e-09 0.32
HDAC5_HUMAN HDAC5 Histone deacetylase 5 2.707e-08 0.38
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 3.556e-08 0.36
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 1.129e-07 0.28
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.47e-07 0.30
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 7.141e-07 0.35
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 8.511e-07 0.36
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.024e-06 0.32
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 1.339e-06 0.38
FES_HUMAN FES Tyrosine-protein kinase Fes/Fps 1.357e-06 0.35
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 2.206e-06 0.31
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 4.361e-06 0.35
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 5.75e-06 0.31
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 6.192e-06 0.35
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 6.419e-06 0.35
FRK_HUMAN FRK Tyrosine-protein kinase FRK 6.869e-06 0.35
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 7.616e-06 0.35
B5ATN6_PSEAI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.472e-06 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 9.593e-06 0.34

Adiphenine

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 9.593e-10 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.002643 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.119e-97 0.56
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 9.55e-58 0.31
CBX8_HUMAN CBX8 Chromobox protein homolog 8 8.293e-52 0.31
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 1.075e-51 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 1.704e-46 0.56
CBX7_HUMAN CBX7 Chromobox protein homolog 7 7.399e-42 0.31
CBX5_HUMAN CBX5 Chromobox protein homolog 5 4.067e-39 0.31
Q9Z1J7_RAT Slc1a5 Amino acid transporter 2.057e-37 0.30
ACER2_HUMAN ACER2 Alkaline ceramidase 2 3.56e-37 0.29
CBX2_HUMAN CBX2 Chromobox protein homolog 2 1.332e-36 0.29
CBX6_HUMAN CBX6 Chromobox protein homolog 6 1.332e-36 0.29
CDY1_HUMAN CDY1; CDY1B Testis-specific chromodomain protein Y 1 1.332e-36 0.29
CDYL_HUMAN CDYL Chromodomain Y-like protein 1.332e-36 0.29
GPR88_MOUSE Gpr88 Probable G-protein coupled receptor 88 7.62e-36 0.28
GLT_PYRHO Glutamate transporter homolog 9.362e-36 0.28
Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 1.609e-35 0.28
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 4.882e-35 0.57
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.359e-29 0.40
BLAB_BACCE Metallo-beta-lactamase type 2 9.005e-29 0.32
PHLC_BACCE plc Phospholipase C 3.441e-28 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 1.767e-27 0.34
ACE_MOUSE Ace Angiotensin-converting enzyme 2.47e-27 0.31
ERG2_YEAST ERG2 C-8 sterol isomerase 7.064e-26 0.40
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 4.812e-25 0.56
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.473e-23 0.36
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.435e-23 0.39
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 4.989e-23 0.28
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.756e-22 0.63
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.184e-22 0.34
AOC3_HUMAN AOC3 Membrane primary amine oxidase 8.734e-21 0.38
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.4e-20 0.63
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.819e-19 0.63
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 7.484e-19 0.31
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 3.815e-18 0.40
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 4.879e-18 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 3.331e-16 0.63
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.441e-16 0.35
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 7.772e-16 0.35
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 7.772e-16 0.30
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 4.441e-15 0.29
CNGA1_BOVIN CNGA1 cGMP-gated cation channel alpha-1 6.106e-15 0.28
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 6.328e-15 0.28
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.421e-14 0.32
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 1.676e-14 0.32
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 2.587e-14 0.34
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.963e-14 0.31
KPCA_MOUSE Prkca Protein kinase C alpha type 5.529e-14 0.32
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 6.417e-14 0.35
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 8.504e-14 0.51
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.136e-13 0.53
EST1_RABIT Liver carboxylesterase 1 3.019e-13 0.34
CHLE_HUMAN BCHE Cholinesterase 7.743e-13 0.48
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.097e-12 0.30
ACES_HUMAN ACHE Acetylcholinesterase 1.415e-12 0.42
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.602e-12 0.46
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.975e-12 0.30
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 7.838e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 7.838e-12 0.29
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.699e-11 0.32
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 7.579e-11 0.40
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 9.112e-11 0.29
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 1.105e-10 0.29
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 1.105e-10 0.29
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 1.156e-10 0.35
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 2.663e-10 0.32
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 2.921e-10 0.35
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 7.375e-10 0.63
CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 8.972e-10 0.28
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 9.06e-10 0.31
PAOX_HUMAN PAOX Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 9.46e-10 0.28
BLAB_AERHY cphA Metallo-beta-lactamase type 2 1.863e-09 0.30
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 1.883e-09 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.477e-09 0.37
ACES_RAT Ache Acetylcholinesterase 4.581e-09 0.34
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5.908e-09 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.475e-09 0.52
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.742e-08 0.38
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 1.742e-08 0.35
NK1R_RAT Tacr1 Substance-P receptor 1.862e-08 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.487e-08 0.31
EST2_HUMAN CES2 Cocaine esterase 3.196e-08 0.33
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.337e-08 0.40
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 7.986e-08 0.31
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 8.712e-08 0.32
Q17SB2_PLAFA Plasmepsin 4 1e-07 0.30
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.227e-07 0.28
ACES_ELEEL ache Acetylcholinesterase 1.283e-07 0.35
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.436e-07 0.30
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.914e-07 0.29
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.936e-07 0.43
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 2.63e-07 0.38
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 4.701e-07 0.35
CHLE_HORSE BCHE Cholinesterase 4.798e-07 0.35
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.217e-07 0.30
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7.425e-07 0.31
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 9.977e-07 0.50
CBPA1_BOVIN CPA1 Carboxypeptidase A1 1.129e-06 0.36
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 1.385e-06 0.30
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.394e-06 0.40
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.435e-06 0.32
CATB_BOVIN CTSB Cathepsin B 1.499e-06 0.31
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.58e-06 0.32
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 1.907e-06 0.28
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.034e-06 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.051e-06 0.42
NR1H4_MOUSE Nr1h4 Bile acid receptor 2.488e-06 0.30
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 2.683e-06 0.30
EST1_HUMAN CES1 Liver carboxylesterase 1 3.024e-06 0.33
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 4.816e-06 0.30
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.818e-06 0.30
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 5.246e-06 0.35
EST1_PIG Liver carboxylesterase 5.57e-06 0.29
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 6.999e-06 0.29
KITH_HUMAN TK1 Thymidine kinase, cytosolic 8.92e-06 0.36
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 9.636e-06 0.29

Linzagolix

GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 5.623e-09 1.00
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 6.118e-09 0.32
EGLN3_HUMAN EGLN3 Egl nine homolog 3 1.531e-08 0.32
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.726e-06 0.31

Mitapivat

KPYR_HUMAN PKLR Pyruvate kinase PKLR 0 0.73
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.36e-113 0.39
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 2.182e-69 0.39
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 8.694e-58 0.34
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 7.495e-53 0.47
TNKS1_MOUSE Tnks Poly [ADP-ribose] polymerase tankyrase-1 7.528e-39 0.31
TNKS2_MOUSE Tnks2 Poly [ADP-ribose] polymerase tankyrase-2 7.528e-39 0.31
CCR3_MACMU CCR3 C-C chemokine receptor type 3 2.435e-37 0.30
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 3.525e-35 0.36
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 4.033e-33 0.32
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 2.387e-32 0.29
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.708e-31 0.46
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.798e-30 0.47
SFRP1_HUMAN SFRP1 Secreted frizzled-related protein 1 1.087e-27 0.32
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 3.462e-27 0.32
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.832e-23 0.32
PTPRS_HUMAN PTPRS Receptor-type tyrosine-protein phosphatase S 1.676e-22 0.31
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 1.211e-18 0.30
PTR1_LEIMA PTR1 Pteridine reductase 1 3.466e-18 0.35
DRD2_MOUSE Drd2 D(2) dopamine receptor 3.785e-18 0.32
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 1.012e-17 0.34
TF65_HUMAN RELA Transcription factor p65 1.19e-17 0.36
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 1.11e-16 0.29
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 7.772e-16 0.29
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 2.209e-14 0.39
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.276e-14 0.39
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.672e-13 0.45
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 4.799e-13 0.45
PCKGC_HUMAN PCK1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 5.57e-13 0.44
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.128e-12 0.33
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 2.177e-12 0.30
MEP50_HUMAN WDR77 Methylosome protein 50 3.404e-12 0.33
RET4_HUMAN RBP4 Retinol-binding protein 4 7.75e-12 0.32
V5TFZ2_9FLAV Nonstructural protein 5 1.462e-11 0.31
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 7.038e-11 0.45
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 2.51e-10 0.30
MTLR_HUMAN MLNR Motilin receptor 2.983e-10 0.33
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.021e-09 0.30
PDE4C_HUMAN PDE4C cAMP-specific 3',5'-cyclic phosphodiesterase 4C 1.611e-09 0.29
FACE2_HUMAN RCE1 CAAX prenyl protease 2 1.803e-09 0.34
PCKGC_RAT Pck1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 2.948e-09 0.29
DCPS_MOUSE Dcps m7GpppX diphosphatase 3.598e-09 0.29
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 4.344e-09 0.34
C0L093_TOBAC Acetolactate synthase 4.608e-09 0.28
G3I1B6_CRIGR 5-hydroxytryptamine receptor 1.547e-08 0.29
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.73e-08 0.42
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 1.94e-08 0.29
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 3.663e-08 0.36
TYSY_ECOLI thyA Thymidylate synthase 3.804e-08 0.41
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 6.875e-08 0.43
WNT3A_MOUSE Wnt3a Protein Wnt-3a 7.347e-08 0.31
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.202e-07 0.33
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 2.271e-07 0.33
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 5.618e-07 0.35
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 5.744e-07 0.44
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 8.204e-07 0.30
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 8.308e-07 0.34
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 1.186e-06 0.28
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.441e-06 0.42
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.285e-06 0.30
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.933e-06 0.35
BGAL_ECOLX lacZ Beta-galactosidase 4.726e-06 0.35
SGK1_HUMAN SGK1 Serine/threonine-protein kinase Sgk1 5.708e-06 0.32
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.866e-06 0.35
DRD2_HUMAN DRD2 D(2) dopamine receptor 8.994e-06 0.41
LSS_HUMAN LSS Lanosterol synthase 9.326e-06 0.31

Inavolisib

IDHC_HUMAN IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 4.756e-308 0.39
M3K14_HUMAN MAP3K14 Mitogen-activated protein kinase kinase kinase 14 5.173e-56 0.39
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 8.882e-16 0.38
P2RX3_RAT P2rx3 P2X purinoceptor 3 2.187e-14 0.34
P2RX2_HUMAN P2RX2 P2X purinoceptor 2 2.097e-13 0.34
IDHP_HUMAN IDH2 Isocitrate dehydrogenase [NADP], mitochondrial 4.818e-09 0.34

Durlobactam

Q93LQ9_KLEPN KPC-2 Beta-lactamase 3.816e-211 0.39
Q8RL90_PSEAI ampC Beta-lactamase 1.047e-209 0.39
Q8RLA6_ACIBA blaOXA-33 Beta-lactamase 9.984e-71 0.37
AMPC_PSEAE ampC Beta-lactamase 5.845e-08 0.50
AMPC_ENTCL ampC Beta-lactamase 5.079e-07 0.50

Fluoroestradiol_F-18

STS_HUMAN STS Steryl-sulfatase 1.898e-156 0.65
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 2.425e-82 0.69
Q95MF8_PIG Sulfotransferase 1.672e-76 0.46
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.379e-72 0.80
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.012e-42 0.80
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 3.256e-42 0.69
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 1.839e-40 0.59
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 4.67e-40 0.53
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 7.814e-36 0.69
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 5.496e-33 0.46
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 6.051e-32 0.80
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.687e-31 0.51
ESR1_HUMAN ESR1 Estrogen receptor 7.536e-31 0.80
ESR2_HUMAN ESR2 Estrogen receptor beta 1.885e-27 0.80
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 4.155e-27 0.69
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 4.437e-26 0.42
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 4.386e-25 0.31
ESR1_MOUSE Esr1 Estrogen receptor 5.829e-21 0.69
ESR2_MOUSE Esr2 Estrogen receptor beta 5.829e-21 0.69
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 1.369e-18 0.69
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.133e-18 0.49
ADCY5_RAT Adcy5 Adenylate cyclase type 5 2.262e-18 0.34
Q690N0_BOVIN PGR Progesterone receptor 5.107e-15 0.69
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 6.994e-15 0.44
ESR1_RAT Esr1 Estrogen receptor 2.831e-14 0.69
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.73e-14 0.69
CP19A_HUMAN CYP19A1 Aromatase 9.257e-11 0.59
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.157e-10 0.69
ESR2_RAT Esr2 Estrogen receptor beta 3.837e-08 0.69
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.339e-07 0.47
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 1.669e-07 0.69
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.518e-07 0.80
ANDR_RAT Ar Androgen receptor 2.91e-07 0.69
C11B2_RAT Cyp11b2 Cytochrome P450 11B2, mitochondrial 4.171e-07 0.32
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 6.829e-07 0.53
DRD2_BOVIN DRD2 D(2) dopamine receptor 4.55e-06 0.32

Bortezomib_D-mannitol

RENI_HUMAN REN Renin 1.839e-131 0.38
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 4.288e-129 0.34
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 6.227e-111 0.34
CBX7_HUMAN CBX7 Chromobox protein homolog 7 1.95e-103 0.35
CBX8_HUMAN CBX8 Chromobox protein homolog 8 7.943e-98 0.34
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 1.388e-94 0.44
RENI_RAT Ren1 Renin 8.903e-91 0.34
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.793e-80 0.38
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.099e-79 0.33
CATB_BOVIN CTSB Cathepsin B 3.855e-78 0.44
NEP_MOUSE Mme Neprilysin 3.224e-72 0.36
PEPC_HUMAN PGC Gastricsin 1.452e-68 0.31
MMP8_RAT Mmp8 Neutrophil collagenase 2.405e-68 0.37
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 6.394e-66 0.44
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 3.245e-65 0.37
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 3.245e-65 0.37
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 3.245e-65 0.37
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 3.245e-65 0.37
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 3.245e-65 0.37
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 3.245e-65 0.37
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 3.245e-65 0.37
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 3.245e-65 0.37
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 3.245e-65 0.37
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 3.245e-65 0.37
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 3.245e-65 0.37
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 3.245e-65 0.37
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 3.245e-65 0.37
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 3.245e-65 0.37
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 3.245e-65 0.37
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 3.245e-65 0.37
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 3.245e-65 0.37
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 3.245e-65 0.37
MBOA4_HUMAN MBOAT4 Ghrelin O-acyltransferase 4.822e-63 0.35
VM1B1_BOTAS Snake venom metalloproteinase BaP1 8.813e-60 0.38
MMP9_RAT Mmp9 Matrix metalloproteinase-9 3.333e-59 0.37
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.509e-57 0.39
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 3.55e-57 0.33
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 7.182e-57 0.36
Q4U254_9ENTO protease Protease 3.657e-55 0.39
KLKB1_HUMAN KLKB1 Plasma kallikrein 3.222e-53 0.38
NK2R_MESAU TACR2 Substance-K receptor 7.835e-53 0.33
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 1.328e-52 0.32
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 6.349e-49 0.35
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 6.639e-49 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.645e-48 0.37
AMPB_MOUSE Rnpep Aminopeptidase B 8.334e-48 0.38
AMPL_BOVIN LAP3 Cytosol aminopeptidase 8.334e-48 0.38
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 2.313e-47 0.31
KISSR_HUMAN KISS1R KiSS-1 receptor 1.26e-42 0.34
KLK3_HUMAN KLK3 Prostate-specific antigen 1.735e-42 0.32
CBX5_HUMAN CBX5 Chromobox protein homolog 5 1.846e-42 0.34
PEPA_PIG PGA Pepsin A 5.345e-41 0.34
CATD_BOVIN CTSD Cathepsin D 7.691e-41 0.35
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.63e-40 0.31
CBX2_HUMAN CBX2 Chromobox protein homolog 2 2.565e-40 0.32
CBX6_HUMAN CBX6 Chromobox protein homolog 6 2.565e-40 0.32
CDY1_HUMAN CDY1; CDY1B Testis-specific chromodomain protein Y 1 2.565e-40 0.32
CDYL_HUMAN CDYL Chromodomain Y-like protein 2.565e-40 0.32
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 3.023e-40 0.35
POLG_HRV14 Genome polyprotein 1.271e-39 0.31
CATB_HUMAN CTSB Cathepsin B 2.466e-39 0.37
PAPA1_CARPA Papain 6.582e-39 0.34
PEPT1_DERPT DERP1 Peptidase 1 2.75e-38 0.34
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 7.035e-38 0.37
Q72874_9HIV1 pol Pol polyprotein 2.258e-37 0.36
NEP_RABIT MME Neprilysin 3.322e-37 0.35
G1FEK8_9CALI Protease 4.99e-37 0.29
I1U3K2_9CALI POL Nonstructural polyprotein 4.99e-37 0.29
A0A1D8D5K2_HE71 Genome polyprotein 1.147e-36 0.29
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 4.398e-36 0.29
NK1R_CAVPO TACR1 Substance-P receptor 1.205e-35 0.33
RENI1_MOUSE Ren1 Renin-1 2.567e-35 0.35
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 6.174e-35 0.33
CYSP_TRYCR Cruzipain 1.092e-34 0.37
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 1.188e-34 0.37
THER_BACTH npr Thermolysin 1.507e-34 0.33
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.307e-33 0.31
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 1.844e-33 0.36
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 2.406e-33 0.37
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 2.406e-33 0.37
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 2.406e-33 0.37
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 2.406e-33 0.37
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 2.406e-33 0.37
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 2.406e-33 0.37
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 2.406e-33 0.37
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 2.406e-33 0.37
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 2.406e-33 0.37
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 2.406e-33 0.37
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 2.406e-33 0.37
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 2.406e-33 0.37
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 2.406e-33 0.37
CATL1_HUMAN CTSL Cathepsin L1 4.917e-33 0.38
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 6.486e-33 0.34
PTPRB_HUMAN PTPRB Receptor-type tyrosine-protein phosphatase beta 8.318e-33 0.37
KLK1_HUMAN KLK1 Kallikrein-1 1.463e-32 0.36
MMP1_HUMAN MMP1 Interstitial collagenase 1.467e-32 0.37
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.99e-32 0.31
SSPA_STAAU sspA Glutamyl endopeptidase 4.524e-32 0.33
MC3R_MOUSE Mc3r Melanocortin receptor 3 8.943e-32 0.30
PLM1_PLAFA Plasmepsin-1 1.102e-31 0.35
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 1.256e-31 0.37
NK2R_RAT Tacr2 Substance-K receptor 5.8e-30 0.30
ACE_MOUSE Ace Angiotensin-converting enzyme 1.782e-28 0.36
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 1.627e-27 0.35
A3EZI9_9HEPC NS3 Genome polyprotein 2.88e-27 0.39
CARP_YEAST PEP4 Saccharopepsin 5.245e-27 0.33
NK3R_CAVPO TACR3 Neuromedin-K receptor 7.4e-27 0.30
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 9.603e-27 0.37
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.598e-26 0.37
EDNRB_RAT Ednrb Endothelin receptor type B 7.637e-26 0.32
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 8.938e-26 0.32
CATK_HUMAN CTSK Cathepsin K 2.353e-25 0.38
PEPA1_PENJA Penicillopepsin-1 2.641e-25 0.28
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 2.959e-25 0.34
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 3.011e-25 0.34
PLMN_BOVIN PLG Plasminogen 7.906e-25 0.31
HPGDS_MOUSE Hpgds Hematopoietic prostaglandin D synthase 8.943e-25 0.30
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.226e-24 0.36
AMPB_RAT Rnpep Aminopeptidase B 1.828e-24 0.38
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.576e-24 0.34
Q9NBD4_PLAFA Cysteine protease falcipain-2 3.317e-24 0.30
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 9.957e-24 0.38
Q95PM0_TRYBR rhodesain Cysteine protease 1.206e-23 0.33
CATL2_HUMAN CTSV Cathepsin L2 1.554e-23 0.34
CATK_RAT Ctsk Cathepsin K 2.917e-23 0.30
OPRD_RAT Oprd1 Delta-type opioid receptor 7.529e-23 0.35
OPRM_RAT Oprm1 Mu-type opioid receptor 2.719e-22 0.35
NEP_HUMAN MME Neprilysin 3.24e-22 0.33
NEP_PIG MME Neprilysin 9.062e-22 0.34
AMPN_PIG ANPEP Aminopeptidase N 2.515e-21 0.38
NEP_RAT Mme Neprilysin 1.159e-20 0.33
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 4.395e-20 0.37
D2K2A8_9HEPC NS4A Non-structural protein 4A 4.76e-20 0.39
MMP3_HUMAN MMP3 Stromelysin-1 6.189e-20 0.37
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 9.972e-20 0.34
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.417e-19 0.39
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 2.079e-19 0.31
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 3.192e-19 0.32
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 5.705e-19 0.30
PSDE_HUMAN PSMD14 26S proteasome non-ATPase regulatory subunit 14 1.364e-18 0.37
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 1.372e-18 0.29
PLM2_PLAFA Plasmepsin-2 1.396e-18 0.35
O68720_YERPE yopH Targeted effector protein 2.015e-18 0.31
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 7.249e-18 0.31
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 8.465e-18 0.34
ACE_HUMAN ACE Angiotensin-converting enzyme 1.653e-17 0.34
CATL1_BOVIN CTSL Cathepsin L1 1.834e-17 0.33
CATD_HUMAN CTSD Cathepsin D 2.984e-17 0.35
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 3.151e-17 0.37
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.11e-16 0.32
O07911_STAAU agrC AgrC 1.11e-16 0.32
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.22e-16 0.36
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.331e-16 0.37
CATS_HUMAN CTSS Cathepsin S 4.441e-16 0.39
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.443e-15 0.30
AMPX_VIBPR Bacterial leucyl aminopeptidase 2.331e-15 0.38
AMP1_PLAFQ M1 family aminopeptidase 2.442e-15 0.38
CATE_HUMAN CTSE Cathepsin E 3.664e-15 0.30
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 3.664e-15 0.32
NK1R_RAT Tacr1 Substance-P receptor 7.105e-15 0.35
CD36_RAT Cd36 Platelet glycoprotein 4 1.477e-14 0.30
MMP8_HUMAN MMP8 Neutrophil collagenase 2.376e-14 0.37
ENV_HV1H2 env Envelope glycoprotein gp160 2.431e-14 0.31
MMP2_HUMAN MMP2 72 kDa type IV collagenase 3.608e-14 0.40
PAR1_HUMAN F2R Proteinase-activated receptor 1 4.552e-14 0.35
CBPA1_HUMAN CPA1 Carboxypeptidase A1 5.052e-14 0.31
AMPN_MOUSE Anpep Aminopeptidase N 5.929e-14 0.38
EDNRA_MOUSE Ednra Endothelin-1 receptor 8.193e-14 0.29
PA_I34A1 PA Polymerase acidic protein 1.634e-13 0.31
MMP7_HUMAN MMP7 Matrilysin 2.128e-13 0.35
BODG_PSESK Gamma-butyrobetaine dioxygenase 2.289e-13 0.29
MC3R_HUMAN MC3R Melanocortin receptor 3 2.667e-13 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 1.007e-12 0.38
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.665e-12 0.35
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 6.448e-12 0.36
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 6.994e-12 0.34
Q9YQ12_9HIV1 protease Protease 1.984e-11 0.34
POLG_HCV1 Genome polyprotein 4.296e-11 0.38
OPRD_MOUSE Oprd1 Delta-type opioid receptor 7.657e-11 0.35
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 7.722e-11 0.31
ACE_RAT Ace Angiotensin-converting enzyme 1.037e-10 0.35
Q9YQ30_9PLVG HIV-1 protease HIV-1 protease 1.184e-10 0.38
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1.429e-10 0.31
GLNA_HUMAN GLUL Glutamine synthetase 1.441e-10 0.33
Q6DMN0_TOXGO CPL Cathepsin L 3.238e-10 0.30
CATB_RAT Ctsb Cathepsin B 3.307e-10 0.29
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 5.258e-10 0.34
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 5.634e-10 0.34
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 6.264e-10 0.31
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 6.557e-10 0.33
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 7.993e-10 0.37
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 9.153e-10 0.30
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.027e-09 0.38
CARP_RHICH Rhizopuspepsin 1.171e-09 0.30
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 1.89e-09 0.30
PEPA5_HUMAN PGA5 Pepsin A-5 2.092e-09 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 2.349e-09 0.35
CTRA_BOVIN Chymotrypsinogen A 3.68e-09 0.31
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.089e-09 0.38
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 7.248e-09 0.31
NK3R_RAT Tacr3 Neuromedin-K receptor 7.305e-09 0.29
CASP9_HUMAN CASP9 Caspase-9 7.532e-09 0.30
CBPA1_BOVIN CPA1 Carboxypeptidase A1 8.946e-09 0.33
ANF_HUMAN NPPA Natriuretic peptides A 1.709e-08 0.30
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 1.728e-08 0.30
EDNRA_HUMAN EDNRA Endothelin-1 receptor 2.81e-08 0.32
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 1.77e-07 0.29
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.848e-07 0.33
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 2.254e-07 0.30
APH1A_HUMAN APH1A Gamma-secretase subunit APH-1A 3.132e-07 0.31
APH1B_HUMAN APH1B Gamma-secretase subunit APH-1B 3.132e-07 0.31
NICA_HUMAN NCSTN Nicastrin 3.132e-07 0.31
PEN2_HUMAN PSENEN Gamma-secretase subunit PEN-2 3.154e-07 0.31
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 3.205e-07 0.29
PSN2_HUMAN PSEN2 Presenilin-2 3.222e-07 0.31
ACE_RABIT ACE Angiotensin-converting enzyme 4.082e-07 0.33
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 4.18e-07 0.30
PSN1_HUMAN PSEN1 Presenilin-1 6.189e-07 0.31
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 7.29e-07 0.31
MC4R_HUMAN MC4R Melanocortin receptor 4 7.745e-07 0.31
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 7.797e-07 0.31
OPRK_RAT Oprk1 Kappa-type opioid receptor 8.626e-07 0.32
NK3R_HUMAN TACR3 Neuromedin-K receptor 8.679e-07 0.31
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 9.073e-07 0.32
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 9.97e-07 0.32
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 1.119e-06 0.31
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.276e-06 0.37
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.394e-06 0.34
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.506e-06 0.31
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.782e-06 0.28
PGTB1_HUMAN PGGT1B Geranylgeranyl transferase type-1 subunit beta 2.268e-06 0.31
NK2R_HUMAN TACR2 Substance-K receptor 4.026e-06 0.32
R1AB_SARS rep Replicase polyprotein 1ab 4.383e-06 0.30
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 6.181e-06 0.32
CAN1_RAT Capn1 Calpain-1 catalytic subunit 7.607e-06 0.28
CCNA2_HUMAN CCNA2 Cyclin-A2 8.749e-06 0.30

Foslevodopa

TPH1_HUMAN TPH1 Tryptophan 5-hydroxylase 1 2.613e-131 0.37
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 3.782e-92 0.40
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.242e-85 0.50
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 7.447e-74 0.34
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 1.621e-73 0.35
TY3H_RAT Th Tyrosine 3-monooxygenase 1.885e-68 0.55
GLN1B_ECOLI glnA Glutamine synthetase 1.424e-67 0.32
AMPL_PIG LAP3 Cytosol aminopeptidase 2.511e-66 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 7.804e-65 0.43
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 8.569e-62 0.35
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 2.566e-58 0.39
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.002e-56 0.46
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.788e-53 0.38
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 1.978e-53 0.35
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 4.608e-48 0.34
MURI_LACFE murI Glutamate racemase 9.029e-48 0.38
DDC_MOUSE Ddc Aromatic-L-amino-acid decarboxylase 1.522e-44 0.35
AMPN_PIG ANPEP Aminopeptidase N 6.624e-44 0.35
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 2.401e-43 0.54
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 5.166e-42 0.33
KYNU_RAT Kynu Kynureninase 2.281e-40 0.32
AMPN_HUMAN ANPEP Aminopeptidase N 9.21e-40 0.34
GRM4_MOUSE Grm4 Metabotropic glutamate receptor 4 1.921e-39 0.31
CFAD_RAT Cfd Complement factor D 1.176e-38 0.31
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 1.918e-38 0.31
OTC_HUMAN OTC Ornithine carbamoyltransferase, mitochondrial 6.694e-38 0.30
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 1.572e-36 0.29
GLT_PYRHO Glutamate transporter homolog 3.875e-36 0.29
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 5.019e-36 0.44
AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 1.097e-35 0.28
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.545e-34 0.34
TY3H_HUMAN TH Tyrosine 3-monooxygenase 8.499e-34 0.55
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.768e-31 0.35
EAA4_RAT Slc1a6 Excitatory amino acid transporter 4 4.918e-30 0.30
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 9.712e-29 0.32
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 1.808e-28 0.42
CSK_HUMAN CSK Tyrosine-protein kinase CSK 1.944e-27 0.38
KYNU_HUMAN KYNU Kynureninase 6.376e-27 0.32
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 4.058e-26 0.42
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.807e-24 0.39
FABI_ECOLI fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 5.022e-24 0.35
NK1R_RAT Tacr1 Substance-P receptor 3.965e-23 0.35
NEP_RABIT MME Neprilysin 2.258e-22 0.32
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 9.087e-22 0.36
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 1.804e-21 0.30
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 2.206e-21 0.36
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 5.604e-21 0.44
OPRM_RAT Oprm1 Mu-type opioid receptor 1.071e-20 0.40
Q39829_SOYBN Lipoxygenase 1.948e-20 0.33
OPRD_RAT Oprd1 Delta-type opioid receptor 1.048e-19 0.40
GRIA2_RAT Gria2 Glutamate receptor 2 1.668e-19 0.46
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 3.456e-19 0.36
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 7.785e-19 0.33
GFPT1_HUMAN GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 3.143e-18 0.29
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.615e-18 0.29
EAA3_HUMAN SLC1A1 Excitatory amino acid transporter 3 7.715e-18 0.31
VM1B1_BOTAS Snake venom metalloproteinase BaP1 9.771e-18 0.28
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 1.11e-16 0.33
NEP_MOUSE Mme Neprilysin 1.11e-16 0.38
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 1.11e-16 0.35
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 5.551e-16 0.30
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 8.882e-16 0.33
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 8.882e-16 0.34
OPRM_CAVPO OPRM1 Mu-type opioid receptor 8.882e-16 0.35
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 9.992e-16 0.32
NEP_RAT Mme Neprilysin 1.11e-15 0.35
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.332e-15 0.30
LY96_HUMAN LY96 Lymphocyte antigen 96 1.887e-15 0.29
TPH2_HUMAN TPH2 Tryptophan 5-hydroxylase 2 1.887e-15 0.29
A5A4K8_RABIT MLNR Motilin receptor 3.997e-15 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 6.217e-15 0.43
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 7.327e-15 0.30
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 1.31e-14 0.32
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 2.109e-14 0.32
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 2.109e-14 0.30
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 2.109e-14 0.32
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 8.793e-14 0.31
TTHY_HUMAN TTR Transthyretin 2.033e-13 0.37
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 2.138e-13 0.31
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 3.837e-13 0.29
THB_RAT Thrb Thyroid hormone receptor beta 8.545e-13 0.42
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.31e-12 0.32
NEP_HUMAN MME Neprilysin 2.91e-12 0.32
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 5.06e-12 0.29
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 8.654e-12 0.31
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 1.025e-11 0.35
AMPB_HUMAN RNPEP Aminopeptidase B 4.757e-11 0.30
AROA_ECOLI aroA 3-phosphoshikimate 1-carboxyvinyltransferase 5.882e-11 0.32
OPRD_MOUSE Oprd1 Delta-type opioid receptor 8.033e-11 0.35
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.878e-11 0.29
GRIK5_RAT Grik5 Glutamate receptor ionotropic, kainate 5 3.092e-10 0.32
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.599e-10 0.41
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 6.557e-10 0.33
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 8.781e-10 0.35
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 2.15e-09 0.30
GRIA3_RAT Gria3 Glutamate receptor 3 2.622e-09 0.33
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 2.972e-09 0.30
1433G_HUMAN YWHAG 14-3-3 protein gamma 1.189e-08 0.31
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 1.211e-08 0.30
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 1.429e-08 0.30
CBPA1_BOVIN CPA1 Carboxypeptidase A1 2.24e-08 0.30
GRIK1_HUMAN GRIK1 Glutamate receptor ionotropic, kainate 1 3.408e-08 0.33
OPRK_RAT Oprk1 Kappa-type opioid receptor 3.735e-08 0.33
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 4.95e-08 0.32
CAN_CANAL NCE103 Carbonic anhydrase 6.139e-08 0.32
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 9.801e-08 0.44
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.105e-07 0.31
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 1.106e-07 0.30
JUN_HUMAN JUN Transcription factor AP-1 1.283e-07 0.35
THA_HUMAN THRA Thyroid hormone receptor alpha 1.848e-07 0.42
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 2.101e-07 0.36
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 2.871e-07 0.30
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 4.905e-07 0.29
GRIA1_HUMAN GRIA1 Glutamate receptor 1 5.295e-07 0.31
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 5.51e-07 0.38
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.309e-07 0.31
FOS_HUMAN FOS Proto-oncogene c-Fos 6.962e-07 0.33
POLG_DEN2P Genome polyprotein 8.058e-07 0.29
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 8.793e-07 0.32
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.037e-06 0.45
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 1.039e-06 0.63
RENI_CALJA REN Renin 1.121e-06 0.29
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 2.422e-06 0.32
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 2.709e-06 0.30
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 3.089e-06 0.30
S1PR4_HUMAN S1PR4 Sphingosine 1-phosphate receptor 4 3.447e-06 0.30
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 3.992e-06 0.33
THB_HUMAN THRB Thyroid hormone receptor beta 4.378e-06 0.42
ACE_RAT Ace Angiotensin-converting enzyme 7.038e-06 0.32
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 7.896e-06 0.29
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 8.827e-06 0.29

Berotralstat

CARM1_MOUSE Carm1 Histone-arginine methyltransferase CARM1 2.013e-126 0.43
O77669_CANLF Coagulation factor X 3.317e-52 0.34
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 7.287e-52 0.44
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 1.373e-43 0.36
PDGFA_HUMAN PDGFA Platelet-derived growth factor subunit A 3.067e-37 0.29
FA10_RABIT F10 Coagulation factor X 1.22e-28 0.48
FA10_HUMAN F10 Coagulation factor X 8.902e-18 0.48
FA9_HUMAN F9 Coagulation factor IX 3.064e-14 0.48
FA5_HUMAN F5 Coagulation factor V 9.737e-13 0.35
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 9.792e-13 0.34
ELNE_HUMAN ELANE Neutrophil elastase 4.861e-11 0.30
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 1.614e-10 0.31
THRB_HUMAN F2 Prothrombin 7.021e-07 0.48

Benzhydrocodone

OPRX_CAVPO OPRL1 Nociceptin receptor 9.483e-126 0.59
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.533e-88 0.59
OPRM_HUMAN OPRM1 Mu-type opioid receptor 7.484e-76 0.59
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.974e-69 0.47
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.257e-68 0.59
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.819e-65 0.55
OPRM_CAVPO OPRM1 Mu-type opioid receptor 2.126e-60 0.59
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 2.006e-52 0.48
OPRD_RAT Oprd1 Delta-type opioid receptor 1.512e-51 0.58
OPRM_RAT Oprm1 Mu-type opioid receptor 5.321e-47 0.49
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.313e-46 0.60
SSR1_RAT Sstr1 Somatostatin receptor type 1 7.588e-44 0.33
OPRM_BOVIN OPRM1 Mu-type opioid receptor 7.413e-43 0.42
SSR2_RAT Sstr2 Somatostatin receptor type 2 6.224e-36 0.33
TLR4_MOUSE Tlr4 Toll-like receptor 4 3.823e-32 0.43
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.158e-23 0.45
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 3.608e-20 0.38
ACES_TETCF ache Acetylcholinesterase 1.398e-19 0.36
Q9JKC1_RAT Bche Carboxylic ester hydrolase 3.331e-16 0.32
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 5.551e-16 0.30
ACES_RAT Ache Acetylcholinesterase 4.108e-14 0.32
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 2.346e-10 0.30
OX1R_HUMAN HCRTR1 Orexin receptor type 1 5.756e-07 0.32
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.531e-06 0.28

Prasterone_enantate

CP19A_HUMAN CYP19A1 Aromatase 2.764e-125 0.57
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 8e-72 0.57
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 9.137e-70 0.53
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.549e-60 0.49
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.114e-49 0.57
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.758e-48 0.57
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 9.089e-48 0.31
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 3.724e-46 0.38
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 9.991e-44 0.35
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.051e-39 0.57
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 1.011e-38 0.34
DHB7_HUMAN HSD17B7 3-keto-steroid reductase 4.239e-37 0.30
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 5.462e-33 0.42
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 3.017e-31 0.48
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 9.209e-30 0.38
CP125_MYCTU cyp125 Steroid C26-monooxygenase 9.286e-30 0.37
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 9.995e-29 0.36
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.549e-28 0.41
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.008e-27 0.34
KPCA_RAT Prkca Protein kinase C alpha type 1.736e-25 0.36
AT2A1_RABIT ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 6.326e-25 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 5.462e-24 0.38
ST1E1_BOVIN SULT1E1 Sulfotransferase 1E1 1.444e-23 0.29
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 1.493e-23 0.46
PPM1A_HUMAN PPM1A Protein phosphatase 1A 7.318e-23 0.28
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 3.947e-22 0.36
STS_HUMAN STS Steryl-sulfatase 2.592e-20 0.39
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 3.93e-20 0.61
S22A8_RAT Slc22a8 Solute carrier family 22 member 8 1.507e-19 0.31
AT2A1_HUMAN ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.297e-19 0.29
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 9.803e-19 0.30
ERG2_YEAST ERG2 C-8 sterol isomerase 1.081e-18 0.59
TRAR_RHIRD traR Transcriptional activator protein TraR 4.666e-18 0.29
Q690N0_BOVIN PGR Progesterone receptor 1.492e-17 0.32
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 2.22e-16 0.34
LUXR_ALIFS luxR Transcriptional activator protein LuxR 2.22e-16 0.29
ANDR_HUMAN AR Androgen receptor 5.551e-16 0.36
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.332e-15 0.34
ANDR_RAT Ar Androgen receptor 1.665e-15 0.36
LSS_RAT Lss Lanosterol synthase 4.33e-15 0.32
LY96_HUMAN LY96 Lymphocyte antigen 96 6.772e-15 0.28
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.376e-14 0.30
LASR_PSEAE lasR Transcriptional activator protein LasR 3.175e-12 0.29
TLR4_HUMAN TLR4 Toll-like receptor 4 4.421e-12 0.33
B6TK44_MAIZE Cycloeucalenol cycloisomerase 6.736e-12 0.29
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.193e-11 0.37
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 3.555e-11 0.42
Q4QYD9_RAT Heat sensitive channel TRPV3 5.796e-11 0.37
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 7.946e-11 0.29
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 1.176e-10 0.44
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 1.561e-10 0.40
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 6.006e-10 0.59
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.406e-09 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 4.58e-09 0.34
KPCA_HUMAN PRKCA Protein kinase C alpha type 5.863e-09 0.36
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 8.869e-09 0.31
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.881e-08 0.33
ANDR_MOUSE Ar Androgen receptor 4.821e-08 0.36
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 1.282e-07 0.36
HRH3_RAT Hrh3 Histamine H3 receptor 1.8e-07 0.38
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.105e-07 0.29
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 9.305e-07 0.31
ESR1_HUMAN ESR1 Estrogen receptor 1.213e-06 0.34
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.185e-06 0.29
IL2_HUMAN IL2 Interleukin-2 5.573e-06 0.31

Iron_polymaltose

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 1.16e-116 0.41
LEG4_HUMAN LGALS4 Galectin-4 4.869e-59 0.36
LEG8_HUMAN LGALS8 Galectin-8 4.869e-59 0.36
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 4.394e-55 0.31
B4EH87_BURCJ Lectin 2.02e-52 0.41
CXB2_HUMAN GJB2 Gap junction beta-2 protein 1.579e-38 0.31
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 5.397e-20 0.32
ENV_HV1H2 env Envelope glycoprotein gp160 3.47e-18 0.40
FGF1_HUMAN FGF1 Fibroblast growth factor 1 3.928e-18 0.32
GDE_RABIT AGL Glycogen debranching enzyme 4.666e-18 0.40
LYAM3_HUMAN SELP P-selectin 8.472e-18 0.33
LYAM1_HUMAN SELL L-selectin 5.218e-15 0.33
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.11e-14 0.32
LEG3_HUMAN LGALS3 Galectin-3 1.865e-11 0.36
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 3.199e-11 0.29
TYRO_HUMAN TYR Tyrosinase 2.995e-09 0.30
O96394_LEIAM Arginase 1.703e-08 0.28
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.679e-06 0.29
CAH13_HUMAN CA13 Carbonic anhydrase 13 2.459e-06 0.32
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 5.231e-06 0.33

Ferric_derisomaltose

FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.329e-115 0.43
MPRI_HUMAN IGF2R Cation-independent mannose-6-phosphate receptor 1.179e-61 0.35
LEG4_HUMAN LGALS4 Galectin-4 7.866e-60 0.37
LEG8_HUMAN LGALS8 Galectin-8 7.866e-60 0.37
B4EH87_BURCJ Lectin 1.133e-53 0.43
CXB2_HUMAN GJB2 Gap junction beta-2 protein 7.545e-40 0.32
GDE_RABIT AGL Glycogen debranching enzyme 1.98e-21 0.48
AMYP_HUMAN AMY2A Pancreatic alpha-amylase 2.444e-20 0.32
FGF1_HUMAN FGF1 Fibroblast growth factor 1 9.895e-19 0.33
LYAM1_HUMAN SELL L-selectin 1.201e-18 0.32
B4GT1_HUMAN B4GALT1 Beta-1,4-galactosyltransferase 1 4.879e-18 0.29
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.11e-16 0.31
ENV_HV1H2 env Envelope glycoprotein gp160 4.441e-16 0.35
LYAG_RAT Gaa Lysosomal alpha-glucosidase 8.882e-16 0.48
FGF2_HUMAN FGF2 Fibroblast growth factor 2 3.664e-15 0.33
LEG3_HUMAN LGALS3 Galectin-3 3.397e-14 0.37
CD69_HUMAN CD69 Early activation antigen CD69 2.368e-13 0.33
SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 2.688e-13 0.34
SUIS_RAT Si Sucrase-isomaltase, intestinal 1.045e-12 0.48
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 3.963e-11 0.33
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 5.025e-11 0.33
LYAM3_HUMAN SELP P-selectin 2.6e-10 0.32
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 6.272e-10 0.32
TYRO_HUMAN TYR Tyrosinase 1.562e-09 0.31
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.684e-08 0.30
MAG_HUMAN MAG Myelin-associated glycoprotein 7.799e-08 0.29
LEG9_HUMAN LGALS9 Galectin-9 1.14e-06 0.29
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 2.629e-06 0.29
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 3.408e-06 0.34
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 8.119e-06 0.29

Gallium_Ga-68_gozetotide

FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 7.222e-110 0.84
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 3.77e-54 0.32
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 8.397e-48 0.38
TYTR_CRIFA TPR Trypanothione reductase 3.737e-47 0.38
PSB6_YEAST PRE7 Proteasome subunit beta type-6 1.046e-36 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 4.097e-35 0.33
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.827e-31 0.31
DLG4_HUMAN DLG4 Disks large homolog 4 3.936e-31 0.31
TYSY_MOUSE Tyms Thymidylate synthase 6.089e-31 0.31
MMP10_HUMAN MMP10 Stromelysin-2 5.462e-29 0.33
PSB5_YEAST PRE2 Proteasome subunit beta type-5 2.576e-18 0.29
DYR_MOUSE Dhfr Dihydrofolate reductase 1.11e-16 0.32
MMP8_HUMAN MMP8 Neutrophil collagenase 1.11e-16 0.33
TYSY_HUMAN TYMS Thymidylate synthase 2.22e-16 0.31
DYR_ENTFC folA Dihydrofolate reductase 3.22e-15 0.31
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 3.664e-15 0.30
TYSY_LACCA thyA Thymidylate synthase 7.938e-14 0.32
GRIA1_RAT Gria1 Glutamate receptor 1 2.283e-13 0.30
Q9I056_PSEAE cpg2 Carboxypeptidase G2 4.673e-13 0.28
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 7.49e-13 0.32
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 8.723e-13 0.36
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 9.56e-13 0.36
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.572e-12 0.38
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 2.992e-12 0.29
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 6.878e-11 0.29
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 7.651e-11 0.32
IDE_HUMAN IDE Insulin-degrading enzyme 1.555e-10 0.34
GRIA1_HUMAN GRIA1 Glutamate receptor 1 3.38e-09 0.31
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 1.214e-08 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.593e-08 0.33
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 2.896e-08 0.36
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.386e-08 0.33
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 3.562e-08 0.31
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 4.248e-08 0.35
MMP3_HUMAN MMP3 Stromelysin-1 9.489e-08 0.35
MMP2_HUMAN MMP2 72 kDa type IV collagenase 2.108e-07 0.35
GRIA3_HUMAN GRIA3 Glutamate receptor 3 5.521e-07 0.30
DYR_HUMAN DHFR Dihydrofolate reductase 7.549e-07 0.31
MMP13_HUMAN MMP13 Collagenase 3 7.729e-07 0.35
FOLR2_HUMAN FOLR2 Folate receptor beta 8.73e-07 0.29
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 1.411e-06 0.32
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.737e-06 0.36
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 4.609e-06 0.34
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 5.684e-06 0.32
DYR_RAT Dhfr Dihydrofolate reductase 5.782e-06 0.31
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 6.678e-06 0.29

Anethole

AHR_RABIT AHR Aryl hydrocarbon receptor 3.643e-107 0.62
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 1.324e-77 0.62
GP183_MOUSE Gpr183 G-protein coupled receptor 183 5.57e-69 0.40
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.182e-52 0.38
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.613e-50 0.57
A4_HUMAN APP Amyloid-beta precursor protein 1.504e-42 0.50
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 3.53e-40 0.55
ACH10_HUMAN CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 7.528e-39 0.31
ACHA9_HUMAN CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 7.528e-39 0.31
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 3.484e-36 0.44
TF65_HUMAN RELA Transcription factor p65 6.299e-34 0.64
GP183_HUMAN GPR183 G-protein coupled receptor 183 3.185e-32 0.40
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 9.491e-29 0.38
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 8.203e-27 0.35
TPPP_BOVIN TPPP Tubulin polymerization-promoting protein 3.081e-26 0.32
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.791e-24 0.76
Q86PR3_AEDAE SCP-2 Sterol carrier protein 2 8.089e-24 0.29
CYSP_PLAFA Trophozoite cysteine proteinase 5.106e-23 0.41
TAU_HUMAN MAPT Microtubule-associated protein tau 1.473e-21 0.55
H9B8T9_CAPHI CTSB Cathepsin B 1.913e-20 0.39
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.753e-20 0.47
CRTN_STAAW crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 5.806e-19 0.36
A0A060INS8_CAPHI CTSH Cathepsin H 8.689e-19 0.39
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.113e-18 0.36
Q49PX0_9POXV N1L N1L 1.842e-17 0.34
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 5.551e-16 0.36
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 5.551e-16 0.53
FFAR4_RAT Ffar4 Free fatty acid receptor 4 6.772e-15 0.28
AHR_HUMAN AHR Aryl hydrocarbon receptor 1.987e-14 0.62
CRTN_STAAE crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 3.253e-14 0.37
Q93EK7_NEIME lgtC LgtC 1.174e-13 0.30
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.326e-13 0.37
CP27A_HUMAN CYP27A1 Sterol 26-hydroxylase, mitochondrial 3.922e-13 0.29
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 3.922e-13 0.29
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.141e-12 0.52
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.507e-12 0.45
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 2.558e-12 0.36
STXA_SHIDY stxA Shiga toxin subunit A 3.273e-12 0.44
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.196e-12 0.44
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.047e-11 0.31
Q4Q5W4_LEIMA Putative squalene synthase 7.648e-11 0.32
MIF_HUMAN MIF Macrophage migration inhibitory factor 9.2e-11 0.39
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.105e-10 0.29
PA_I34A1 PA Polymerase acidic protein 1.688e-10 0.31
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.841e-10 0.36
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 3.47e-10 0.62
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.807e-10 0.31
CALM1_HUMAN CALM1 Calmodulin-1 1.348e-09 0.34
G6PC_HUMAN G6PC Glucose-6-phosphatase 2.916e-09 0.37
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 2.942e-09 0.53
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 6.417e-09 0.34
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 1.134e-08 0.34
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.187e-08 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.29e-08 0.53
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.315e-08 0.44
EST1_RABIT Liver carboxylesterase 1 1.864e-08 0.41
AOC3_BOVIN AOC3 Membrane primary amine oxidase 2.082e-08 0.31
SYUA_HUMAN SNCA Alpha-synuclein 2.899e-08 0.38
LUCI_PHOPY Luciferin 4-monooxygenase 2.997e-08 0.43
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 3.97e-08 0.43
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 5.677e-08 0.38
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 6.978e-08 0.29
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7.455e-08 0.40
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 1.171e-07 0.42
LUCI_PHOPE Luciferin 4-monooxygenase 1.558e-07 0.29
TBA1A_PIG TUBA1A Tubulin alpha-1A chain 1.676e-07 0.53
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.934e-07 0.29
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.502e-07 0.37
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 2.564e-07 0.37
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.094e-07 0.31
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.122e-07 0.45
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 5.944e-07 0.33
POLG_DEN2P Genome polyprotein 7.045e-07 0.29
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 1.584e-06 0.36
OXDA_MOUSE Dao D-amino-acid oxidase 1.788e-06 0.31
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 2.967e-06 0.45
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 3.485e-06 0.62
HDAC1_MOUSE Hdac1 Histone deacetylase 1 5.251e-06 0.29
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.502e-06 0.33
EST2_HUMAN CES2 Cocaine esterase 5.825e-06 0.41
CAH14_HUMAN CA14 Carbonic anhydrase 14 6.432e-06 0.55
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 7.138e-06 0.41

Edotreotide_gallium_Ga-68

SSR5_RAT Sstr5 Somatostatin receptor type 5 4.592e-106 0.64
NK2R_RABIT TACR2 Substance-K receptor 1.624e-92 0.37
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 9.718e-85 0.64
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 4.016e-79 0.40
MC3R_HUMAN MC3R Melanocortin receptor 3 5.033e-78 0.38
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 9.014e-78 0.64
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.201e-72 0.36
EDNRA_PIG EDNRA Endothelin-1 receptor 1.266e-72 0.40
OPRM_RAT Oprm1 Mu-type opioid receptor 3.596e-71 0.60
OPRD_MOUSE Oprd1 Delta-type opioid receptor 2.928e-66 0.42
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.961e-64 0.42
CD36_RAT Cd36 Platelet glycoprotein 4 5.539e-64 0.34
O07911_STAAU agrC AgrC 1.115e-63 0.39
V2R_PIG AVPR2 Vasopressin V2 receptor 1.862e-61 0.36
OPRD_RAT Oprd1 Delta-type opioid receptor 2.333e-61 0.53
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 3.057e-55 0.33
NK2R_MESAU TACR2 Substance-K receptor 3.117e-55 0.38
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 1.348e-52 0.64
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.38e-52 0.36
UR2R_RAT Uts2r Urotensin-2 receptor 6.803e-51 0.58
MC4R_HUMAN MC4R Melanocortin receptor 4 1.3e-50 0.45
V2R_BOVIN AVPR2 Vasopressin V2 receptor 5.325e-49 0.33
NK2R_HUMAN TACR2 Substance-K receptor 5.65e-48 0.41
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 1.601e-47 0.45
GRPR_RAT Grpr Gastrin-releasing peptide receptor 1.433e-45 0.33
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 2.369e-45 0.33
Q5D7U5_CHICK OXTR Oxytocin-like receptor 1.842e-41 0.33
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 2.475e-40 0.31
OXYR_HUMAN OXTR Oxytocin receptor 1.338e-39 0.38
SURA_ECOLI surA Chaperone SurA 1.516e-39 0.31
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 3.57e-39 0.31
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 4.288e-38 0.33
RUVB1_HUMAN RUVBL1 RuvB-like 1 3.875e-36 0.29
MC4R_MOUSE Mc4r Melanocortin receptor 4 4.052e-36 0.36
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 6.637e-36 0.62
GRIA1_RAT Gria1 Glutamate receptor 1 2.053e-35 0.29
KISSR_HUMAN KISS1R KiSS-1 receptor 9.906e-35 0.32
NK2R_RAT Tacr2 Substance-K receptor 1.128e-34 0.35
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.726e-34 0.30
MC5R_HUMAN MC5R Melanocortin receptor 5 4.074e-32 0.38
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 5.681e-32 0.32
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 5.807e-31 0.37
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 6.795e-30 0.33
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 1.173e-29 0.36
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.511e-29 0.64
NK1R_RAT Tacr1 Substance-P receptor 1.899e-29 0.34
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 3.985e-29 0.62
NK1R_MOUSE Tacr1 Substance-P receptor 4.082e-29 0.28
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 4.81e-29 0.35
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.402e-28 0.36
MC3R_MOUSE Mc3r Melanocortin receptor 3 1.989e-27 0.36
FSHR_RAT Fshr Follicle-stimulating hormone receptor 5.245e-27 0.33
OXYR_RAT Oxtr Oxytocin receptor 2.298e-24 0.41
NK3R_RAT Tacr3 Neuromedin-K receptor 3.274e-24 0.34
EDNRA_MOUSE Ednra Endothelin-1 receptor 6.267e-24 0.34
NK1R_CAVPO TACR1 Substance-P receptor 1.198e-23 0.34
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 1.975e-22 0.37
CCKAR_RAT Cckar Cholecystokinin receptor type A 2.197e-22 0.32
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.932e-22 0.41
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 5.062e-22 0.40
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 7.025e-22 0.38
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.426e-21 0.32
NTR1_RAT Ntsr1 Neurotensin receptor type 1 1.715e-21 0.31
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 3.028e-21 0.33
V2R_RAT Avpr2 Vasopressin V2 receptor 1.286e-20 0.41
NK1R_HUMAN TACR1 Substance-P receptor 2.718e-20 0.46
V2R_HUMAN AVPR2 Vasopressin V2 receptor 4.484e-20 0.36
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 8.535e-20 0.36
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.798e-19 0.40
TYRO_HUMAN TYR Tyrosinase 1.229e-18 0.33
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 4.144e-18 0.39
OXYR_MOUSE Oxtr Oxytocin receptor 4.301e-18 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 5.013e-18 0.41
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 5.681e-18 0.28
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 7.066e-18 0.40
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.015e-17 0.42
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 2.797e-17 0.33
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 5.551e-16 0.38
UR2R_HUMAN UTS2R Urotensin-2 receptor 5.551e-16 0.52
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.221e-15 0.34
MMP11_MOUSE Mmp11 Stromelysin-3 1.332e-15 0.29
NEP_RABIT MME Neprilysin 3.109e-15 0.32
AMPN_HUMAN ANPEP Aminopeptidase N 8.771e-15 0.33
ACE_RAT Ace Angiotensin-converting enzyme 2.309e-14 0.32
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 3.975e-14 0.32
ELAS_PSEAE lasB Elastase 1.256e-13 0.31
GRIA1_HUMAN GRIA1 Glutamate receptor 1 2.804e-13 0.32
HDAC5_MOUSE Hdac5 Histone deacetylase 5 2.862e-13 0.29
AGRA_STAAU agrA Accessory gene regulator protein A 3.406e-13 0.32
ENV_HV1H2 env Envelope glycoprotein gp160 3.922e-13 0.29
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.671e-13 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 5.5e-13 0.38
NMBR_HUMAN NMBR Neuromedin-B receptor 1.187e-12 0.30
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.638e-12 0.30
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 3.02e-12 0.36
EDNRB_RAT Ednrb Endothelin receptor type B 4.502e-12 0.33
NRP1_RAT Nrp1 Neuropilin-1 5.884e-12 0.29
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 4.059e-11 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 4.355e-11 0.39
CHIB_SERMA chiB Chitinase B 1.723e-10 0.35
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 5.611e-10 0.44
V1BR_RAT Avpr1b Vasopressin V1b receptor 6.949e-10 0.33
TAT_HV1H2 tat Protein Tat 8.811e-10 0.28
RENI_RAT Ren1 Renin 2.812e-09 0.36
MMP8_RAT Mmp8 Neutrophil collagenase 4.95e-09 0.28
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.067e-08 0.31
RENI_HUMAN REN Renin 1.283e-08 0.39
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.813e-08 0.28
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.085e-08 0.33
ITA3_HUMAN ITGA3 Integrin alpha-3 2.688e-08 0.30
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 3.739e-08 0.29
EDNRA_HUMAN EDNRA Endothelin-1 receptor 4.092e-08 0.34
CBPA1_HUMAN CPA1 Carboxypeptidase A1 4.635e-08 0.33
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 7.801e-08 0.32
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 9.403e-08 0.31
ACE_HUMAN ACE Angiotensin-converting enzyme 4.707e-07 0.33
ITA5_HUMAN ITGA5 Integrin alpha-5 5.965e-07 0.33
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 7.013e-07 0.32
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 9.578e-07 0.29
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 9.91e-07 0.28
CBPB2_HUMAN CPB2 Carboxypeptidase B2 3.191e-06 0.37
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 5.112e-06 0.34
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 5.565e-06 0.31
HDAC6_MOUSE Hdac6 Histone deacetylase 6 8.187e-06 0.29
Q91H74_9FLAV Genome polyprotein 9.901e-06 0.31

Melphalan_flufenamide

SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.38e-105 0.42
OPRM_RAT Oprm1 Mu-type opioid receptor 2.094e-78 0.43
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 8.859e-71 0.40
OPRD_RAT Oprd1 Delta-type opioid receptor 1.321e-65 0.40
CTRB_BOVIN Chymotrypsinogen B 2.097e-65 0.35
NK1R_RAT Tacr1 Substance-P receptor 4.81e-65 0.43
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.431e-58 0.43
CPNS1_PIG CAPNS1 Calpain small subunit 1 1.221e-57 0.36
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.689e-57 0.38
OPRM_CAVPO OPRM1 Mu-type opioid receptor 4.454e-56 0.43
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.988e-48 0.40
KLK1_HUMAN KLK1 Kallikrein-1 3.598e-47 0.40
GRIA1_RAT Gria1 Glutamate receptor 1 1.321e-44 0.30
VM1B1_BOTAS Snake venom metalloproteinase BaP1 3.203e-42 0.38
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 6.86e-41 0.35
PSB6_YEAST PRE7 Proteasome subunit beta type-6 6.244e-40 0.32
LAT1_RAT Slc7a5 Large neutral amino acids transporter small subunit 1 7.215e-40 0.31
PSB5_YEAST PRE2 Proteasome subunit beta type-5 1.462e-38 0.32
CBPA1_HUMAN CPA1 Carboxypeptidase A1 1.549e-38 0.33
MMP9_RAT Mmp9 Matrix metalloproteinase-9 1.88e-38 0.35
AMPB_MOUSE Rnpep Aminopeptidase B 7.101e-36 0.28
AMPL_BOVIN LAP3 Cytosol aminopeptidase 7.101e-36 0.28
Q9ERC0_RAT Npy2r Neuropeptide Y receptor Y2 2.021e-35 0.29
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.552e-33 0.36
HDAC1_RAT Hdac1 Histone deacetylase 1 5.008e-33 0.29
PAR1_HUMAN F2R Proteinase-activated receptor 1 9.653e-33 0.35
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 1.271e-31 0.34
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 1.363e-31 0.32
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 8.343e-31 0.35
SHC1_HUMAN SHC1 SHC-transforming protein 1 6.126e-30 0.29
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 9.135e-30 0.34
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 2.151e-27 0.39
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 8.956e-26 0.41
Q9NBD4_PLAFA Cysteine protease falcipain-2 3.063e-25 0.31
CSK_HUMAN CSK Tyrosine-protein kinase CSK 9.327e-25 0.38
ACE_HUMAN ACE Angiotensin-converting enzyme 5.533e-24 0.38
NEP_HUMAN MME Neprilysin 4.039e-23 0.38
CYSP_TRYCR Cruzipain 6.954e-22 0.34
AKTS1_HUMAN AKT1S1 Proline-rich AKT1 substrate 1 3.565e-21 0.34
OPRD_HUMAN OPRD1 Delta-type opioid receptor 3.95e-21 0.43
MC3R_HUMAN MC3R Melanocortin receptor 3 1.561e-20 0.39
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 3.922e-20 0.39
PAPA1_CARPA Papain 5.621e-20 0.35
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 8.357e-20 0.32
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.72e-19 0.31
GRIA1_HUMAN GRIA1 Glutamate receptor 1 2.87e-19 0.30
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 2.749e-18 0.29
CATH_RAT Ctsh Pro-cathepsin H 3.809e-18 0.29
CATJ_RAT Ctsj Cathepsin J 3.809e-18 0.29
FA10_BOVIN F10 Coagulation factor X 3.932e-18 0.38
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 5.925e-18 0.35
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 6.556e-18 0.28
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 8.47e-18 0.37
LY96_HUMAN LY96 Lymphocyte antigen 96 3.332e-17 0.33
CATB_BOVIN CTSB Cathepsin B 1.11e-16 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.11e-16 0.30
NEP_RABIT MME Neprilysin 2.22e-16 0.33
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 3.331e-16 0.30
NEP_MOUSE Mme Neprilysin 3.331e-16 0.36
Q4U254_9ENTO protease Protease 3.331e-16 0.36
A5A4K8_RABIT MLNR Motilin receptor 6.661e-16 0.35
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.443e-15 0.34
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 1.554e-15 0.28
PYGM_RAT Pygm Glycogen phosphorylase, muscle form 2.776e-15 0.29
CATC_RAT Ctsc Dipeptidyl peptidase 1 3.664e-15 0.29
CATB_RAT Ctsb Cathepsin B 8.438e-15 0.29
AMPN_PIG ANPEP Aminopeptidase N 2.487e-14 0.35
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 2.642e-14 0.34
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 3.064e-14 0.31
THER_BACTH npr Thermolysin 3.109e-14 0.33
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 3.63e-14 0.31
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 8.438e-14 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 8.693e-14 0.36
POLG_CXB3N Genome polyprotein 1.185e-13 0.34
AMPB_RAT Rnpep Aminopeptidase B 2.115e-13 0.29
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 7.936e-13 0.39
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 1.094e-12 0.30
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 2.289e-12 0.30
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 4.179e-12 0.30
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 9.7e-12 0.29
O57585_DANRE oprd1a Opioid receptor homologue 9.7e-12 0.29
AMPX_VIBPR Bacterial leucyl aminopeptidase 1.17e-11 0.28
MC4R_HUMAN MC4R Melanocortin receptor 4 2.369e-11 0.39
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 4.419e-11 0.30
AMP1_PLAFQ M1 family aminopeptidase 6.693e-11 0.31
NEP_PIG MME Neprilysin 7.054e-11 0.32
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.091e-10 0.33
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.105e-10 0.29
AMPN_MOUSE Anpep Aminopeptidase N 1.309e-10 0.28
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 1.577e-10 0.30
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.531e-10 0.38
Q76353_9HIV1 Integrase 3.506e-10 0.38
CATL1_BOVIN CTSL Cathepsin L1 1.577e-09 0.35
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 2.069e-09 0.33
V1AR_RAT Avpr1a Vasopressin V1a receptor 2.753e-09 0.34
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 6.903e-09 0.32
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 1.308e-08 0.30
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.941e-08 0.35
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 3.611e-08 0.34
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 7.185e-08 0.33
NK1R_CAVPO TACR1 Substance-P receptor 1.002e-07 0.32
CATB_HUMAN CTSB Cathepsin B 1.811e-07 0.33
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.848e-07 0.33
MC5R_HUMAN MC5R Melanocortin receptor 5 1.956e-07 0.31
ACE_RAT Ace Angiotensin-converting enzyme 2.421e-07 0.30
CMA1_HUMAN CMA1 Chymase 2.618e-07 0.35
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.79e-07 0.34
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 3.085e-07 0.29
CATG_HUMAN CTSG Cathepsin G 3.371e-07 0.30
CTRA_BOVIN Chymotrypsinogen A 3.709e-07 0.30
AMPN_HUMAN ANPEP Aminopeptidase N 4.676e-07 0.35
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 5.127e-07 0.30
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 5.464e-07 0.28
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 5.577e-07 0.31
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 5.577e-07 0.31
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 5.577e-07 0.31
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 5.577e-07 0.31
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 5.577e-07 0.31
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 5.577e-07 0.31
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 5.577e-07 0.31
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 5.577e-07 0.31
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 5.577e-07 0.31
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 5.577e-07 0.31
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 5.577e-07 0.31
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 5.577e-07 0.31
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 5.577e-07 0.31
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 5.577e-07 0.31
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 5.577e-07 0.31
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 5.577e-07 0.31
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 5.577e-07 0.31
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 5.577e-07 0.31
LKHA4_CAVPO LTA4H Leukotriene A-4 hydrolase 8.408e-07 0.31
KCNQ2_MOUSE Kcnq2 Potassium voltage-gated channel subfamily KQT member 2 8.676e-07 0.30
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.021e-06 0.30
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 1.033e-06 0.30
OPRX_CAVPO OPRL1 Nociceptin receptor 1.069e-06 0.31
CATL1_HUMAN CTSL Cathepsin L1 1.413e-06 0.32
ITB7_HUMAN ITGB7 Integrin beta-7 2.071e-06 0.33
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 2.1e-06 0.31
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.182e-06 0.29
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.873e-06 0.34
CATH_HUMAN CTSH Pro-cathepsin H 2.933e-06 0.33
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 2.95e-06 0.34
NEP_RAT Mme Neprilysin 3.031e-06 0.33
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 3.082e-06 0.34
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 4.537e-06 0.32
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 4.593e-06 0.33
ACE_RABIT ACE Angiotensin-converting enzyme 7.065e-06 0.36
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 9.26e-06 0.34

Vimseltinib

FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 6.761e-103 0.36
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 4.162e-101 0.36
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 2.39e-81 0.36
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 1.284e-60 0.36
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 7.341e-25 0.41
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 3.26e-18 0.36
TTK_HUMAN TTK Dual specificity protein kinase TTK 3.31e-17 0.33
HGF_HUMAN HGF Hepatocyte growth factor 3.297e-14 0.31
TPX2_HUMAN TPX2 Targeting protein for Xklp2 3.619e-10 0.30
F263_HUMAN PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 4.321e-10 0.32
MET_HUMAN MET Hepatocyte growth factor receptor 1.63e-07 0.52
PK3CA_MOUSE Pik3ca Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1.074e-06 0.29
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 1.636e-06 0.34
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 1.819e-06 0.30
CCNA2_HUMAN CCNA2 Cyclin-A2 2.45e-06 0.32
RON_HUMAN MST1R Macrophage-stimulating protein receptor 5.166e-06 0.31

Copper_oxodotreotide_Cu-64

SSR5_RAT Sstr5 Somatostatin receptor type 5 1.362e-102 0.62
CD36_RAT Cd36 Platelet glycoprotein 4 1.1e-95 0.33
NK2R_RABIT TACR2 Substance-K receptor 4.401e-87 0.34
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.291e-86 0.64
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 2.241e-75 0.62
EDNRA_PIG EDNRA Endothelin-1 receptor 1.524e-71 0.40
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 5.285e-69 0.35
MC3R_HUMAN MC3R Melanocortin receptor 3 3.469e-65 0.37
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.416e-64 0.39
OPRM_RAT Oprm1 Mu-type opioid receptor 4.555e-64 0.59
O07911_STAAU agrC AgrC 7.477e-63 0.39
OPRD_MOUSE Oprd1 Delta-type opioid receptor 6.138e-61 0.44
V2R_PIG AVPR2 Vasopressin V2 receptor 3.439e-60 0.35
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.336e-59 0.44
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 7.406e-58 0.34
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 1.871e-57 0.32
OPRD_RAT Oprd1 Delta-type opioid receptor 5.695e-57 0.55
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.743e-55 0.33
UR2R_RAT Uts2r Urotensin-2 receptor 2.464e-50 0.60
NK2R_MESAU TACR2 Substance-K receptor 2.949e-49 0.37
MC5R_MOUSE Mc5r Melanocortin receptor 5 2.441e-48 0.35
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 5.453e-48 0.64
EDNRA_MOUSE Ednra Endothelin-1 receptor 2.578e-46 0.35
NK2R_HUMAN TACR2 Substance-K receptor 9.674e-46 0.40
GRPR_RAT Grpr Gastrin-releasing peptide receptor 1.351e-45 0.33
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 4.16e-44 0.44
SURA_ECOLI surA Chaperone SurA 9.672e-42 0.33
MC4R_HUMAN MC4R Melanocortin receptor 4 3.865e-41 0.42
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.194e-40 0.33
Q5D7U5_CHICK OXTR Oxytocin-like receptor 2.118e-40 0.32
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 3.677e-38 0.33
PSB6_YEAST PRE7 Proteasome subunit beta type-6 2.829e-36 0.29
CADH2_HUMAN CDH2 Cadherin-2 3.875e-36 0.29
OXYR_HUMAN OXTR Oxytocin receptor 8.633e-36 0.37
MC4R_MOUSE Mc4r Melanocortin receptor 4 1.517e-35 0.35
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 1.376e-34 0.30
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 3.228e-34 0.31
NK2R_RAT Tacr2 Substance-K receptor 2.193e-32 0.34
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 4.62e-32 0.64
MC5R_HUMAN MC5R Melanocortin receptor 5 8.4e-31 0.37
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 3.126e-29 0.35
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 3.485e-28 0.64
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 4.602e-28 0.64
MC3R_MOUSE Mc3r Melanocortin receptor 3 4.882e-27 0.35
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 4.294e-26 0.35
V2R_BOVIN AVPR2 Vasopressin V2 receptor 5.312e-26 0.32
FSHR_RAT Fshr Follicle-stimulating hormone receptor 1.246e-25 0.32
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.307e-25 0.38
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 3.545e-25 0.28
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 4.45e-25 0.33
OXYR_RAT Oxtr Oxytocin receptor 3.177e-24 0.41
CELA1_PIG CELA1 Chymotrypsin-like elastase family member 1 6.672e-24 0.29
EDNRB_RAT Ednrb Endothelin receptor type B 1.601e-23 0.33
NK1R_RAT Tacr1 Substance-P receptor 8.02e-23 0.33
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 7.593e-22 0.36
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 9.089e-22 0.33
NTR1_RAT Ntsr1 Neurotensin receptor type 1 1.193e-21 0.31
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.702e-21 0.36
NK3R_RAT Tacr3 Neuromedin-K receptor 4.478e-21 0.33
V2R_RAT Avpr2 Vasopressin V2 receptor 1.253e-20 0.41
KISSR_HUMAN KISS1R KiSS-1 receptor 3.336e-19 0.31
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 3.868e-19 0.36
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.515e-19 0.40
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 8.471e-19 0.40
TYRO_HUMAN TYR Tyrosinase 2.233e-18 0.32
V2R_HUMAN AVPR2 Vasopressin V2 receptor 2.915e-18 0.35
CCKAR_RAT Cckar Cholecystokinin receptor type A 3.546e-18 0.32
PSB5_YEAST PRE2 Proteasome subunit beta type-5 4.185e-18 0.29
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 4.879e-18 0.29
NK1R_CAVPO TACR1 Substance-P receptor 6.107e-18 0.33
V1AR_RAT Avpr1a Vasopressin V1a receptor 6.881e-18 0.41
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.419e-17 0.38
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 4.563e-17 0.32
NK1R_HUMAN TACR1 Substance-P receptor 1.11e-16 0.44
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 3.331e-16 0.33
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.331e-16 0.38
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.441e-16 0.38
UR2R_HUMAN UTS2R Urotensin-2 receptor 5.551e-16 0.54
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 1.221e-15 0.35
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.887e-15 0.34
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 1.632e-14 0.37
NEP_RABIT MME Neprilysin 2.331e-14 0.32
AMPN_HUMAN ANPEP Aminopeptidase N 1.285e-13 0.34
ACE_RAT Ace Angiotensin-converting enzyme 1.522e-13 0.32
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 1.744e-13 0.32
ENV_HV1H2 env Envelope glycoprotein gp160 3.553e-13 0.29
HDAC5_MOUSE Hdac5 Histone deacetylase 5 6.531e-13 0.28
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 7.093e-13 0.31
AGRA_STAAU agrA Accessory gene regulator protein A 7.563e-13 0.31
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.139e-12 0.38
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 1.438e-12 0.37
NRP1_RAT Nrp1 Neuropilin-1 2.602e-12 0.30
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 4.118e-12 0.29
EDNRA_HUMAN EDNRA Endothelin-1 receptor 6.404e-12 0.35
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.932e-11 0.36
HDAC3_HUMAN HDAC3 Histone deacetylase 3 6.656e-11 0.38
V1BR_RAT Avpr1b Vasopressin V1b receptor 1.215e-09 0.32
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 1.512e-09 0.32
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.266e-09 0.43
ELAS_PSEAE lasB Elastase 3.32e-09 0.30
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 1.121e-08 0.29
ITA3_HUMAN ITGA3 Integrin alpha-3 2.558e-08 0.30
HDAC8_HUMAN HDAC8 Histone deacetylase 8 2.626e-08 0.33
CBPA1_HUMAN CPA1 Carboxypeptidase A1 7.268e-08 0.32
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.331e-07 0.31
RENI_HUMAN REN Renin 1.358e-07 0.38
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 1.807e-07 0.30
NMBR_HUMAN NMBR Neuromedin-B receptor 1.91e-07 0.30
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 6.457e-07 0.30
ITA5_HUMAN ITGA5 Integrin alpha-5 9.198e-07 0.32
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 1.081e-06 0.31
RENI_RAT Ren1 Renin 1.322e-06 0.35
CBPB2_HUMAN CPB2 Carboxypeptidase B2 4.593e-06 0.36
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 5.81e-06 0.30
CHIB_SERMA chiB Chitinase B 6.183e-06 0.34
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 7.376e-06 0.33

Flotufolastat_F-18

FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 1.783e-98 0.45
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 2.335e-37 0.29
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 2.335e-37 0.29
DYR_MOUSE Dhfr Dihydrofolate reductase 8.133e-36 0.35
GSP_CRIFA GSP Glutathionylspermidine synthase 1.306e-22 0.29
DYR_ENTFC folA Dihydrofolate reductase 8.633e-19 0.29
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 9.936e-19 0.29
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 1.022e-17 0.28
TYSY_LACCA thyA Thymidylate synthase 2.22e-16 0.35
FURIN_HUMAN FURIN Furin 4.996e-15 0.31
CFAB_HUMAN CFB Complement factor B 1.221e-14 0.30
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 1.377e-14 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 1.517e-13 0.31
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 6.664e-13 0.28
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 4.932e-12 0.31
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 8.927e-12 0.32
DLG4_HUMAN DLG4 Disks large homolog 4 1.032e-11 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.14e-11 0.32
TYSY_MOUSE Tyms Thymidylate synthase 2.199e-11 0.31
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 1.022e-09 0.28
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 4.034e-08 0.29
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 3.457e-07 0.30
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 3.91e-07 0.31
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 6.047e-07 0.31
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 7.308e-07 0.29
DYR_HUMAN DHFR Dihydrofolate reductase 1.044e-06 0.30
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 2.42e-06 0.32
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 3.027e-06 0.28

Zilucoplan

NTR2_HUMAN NTSR2 Neurotensin receptor type 2 9.826e-98 0.35
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.366e-97 0.35
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.202e-86 0.42
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 2.207e-80 0.38
NTR1_RAT Ntsr1 Neurotensin receptor type 1 7.09e-62 0.35
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 1.177e-52 0.34
SURA_ECOLI surA Chaperone SurA 6.532e-44 0.35
RENI_RAT Ren1 Renin 2.942e-43 0.34
GRPR_RAT Grpr Gastrin-releasing peptide receptor 3.091e-43 0.31
SORT_HUMAN SORT1 Sortilin 4.697e-43 0.33
Q5D7U5_CHICK OXTR Oxytocin-like receptor 7.553e-43 0.34
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 3.586e-40 0.32
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.005e-39 0.33
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 1.599e-36 0.36
KISSR_HUMAN KISS1R KiSS-1 receptor 4.72e-33 0.31
MC3R_HUMAN MC3R Melanocortin receptor 3 2.473e-31 0.39
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 5.984e-31 0.38
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 4.993e-30 0.32
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 4.797e-29 0.32
V2R_PIG AVPR2 Vasopressin V2 receptor 2.88e-28 0.30
FSHR_RAT Fshr Follicle-stimulating hormone receptor 9.664e-27 0.33
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.758e-26 0.30
MC4R_MOUSE Mc4r Melanocortin receptor 4 2.454e-26 0.30
OPRM_RAT Oprm1 Mu-type opioid receptor 5.198e-26 0.37
MC3R_MOUSE Mc3r Melanocortin receptor 3 1.447e-25 0.30
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.494e-25 0.38
MC4R_HUMAN MC4R Melanocortin receptor 4 2.852e-25 0.39
OPRD_MOUSE Oprd1 Delta-type opioid receptor 3.437e-23 0.37
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 9.814e-22 0.35
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.07e-20 0.37
OPRD_RAT Oprd1 Delta-type opioid receptor 1.574e-19 0.36
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.911e-19 0.36
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 4.522e-19 0.30
OXYR_MOUSE Oxtr Oxytocin receptor 1.408e-18 0.29
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.644e-18 0.32
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 4.973e-18 0.33
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.232e-14 0.32
NRP1_RAT Nrp1 Neuropilin-1 5.074e-14 0.35
OXYR_HUMAN OXTR Oxytocin receptor 9.115e-14 0.35
MC5R_HUMAN MC5R Melanocortin receptor 5 1.056e-13 0.39
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 4.757e-12 0.36
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 7.412e-12 0.29
O57585_DANRE oprd1a Opioid receptor homologue 7.412e-12 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 9.957e-12 0.31
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 3.234e-11 0.32
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 8.663e-11 0.29
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.467e-10 0.36
AMPN_HUMAN ANPEP Aminopeptidase N 1.656e-09 0.32
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 3.229e-09 0.36
NTR2_RAT Ntsr2 Neurotensin receptor type 2 7.117e-09 0.35
NK1R_RAT Tacr1 Substance-P receptor 7.225e-09 0.36
V1BR_RAT Avpr1b Vasopressin V1b receptor 8.104e-09 0.30
MEN1_HUMAN MEN1 Menin 1.466e-08 0.37
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.144e-08 0.35
NK2R_MESAU TACR2 Substance-K receptor 2.554e-08 0.29
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.674e-08 0.37
V2R_HUMAN AVPR2 Vasopressin V2 receptor 4.435e-08 0.32
NK2R_RAT Tacr2 Substance-K receptor 9.359e-08 0.29
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.164e-07 0.32
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 3.619e-07 0.29
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 5.477e-07 0.33
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 7.571e-07 0.31
OPRK_RAT Oprk1 Kappa-type opioid receptor 9.38e-07 0.31
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 3.119e-06 0.29
NK2R_RABIT TACR2 Substance-K receptor 4.449e-06 0.29
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 4.942e-06 0.33
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 8.662e-06 0.31
CBPB2_HUMAN CPB2 Carboxypeptidase B2 9.449e-06 0.35
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 9.696e-06 0.29

Lazertinib

INSR_HUMAN INSR Insulin receptor 6.238e-88 0.45
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 8.909e-71 0.51
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 2.564e-67 0.37
EGFR_HUMAN EGFR Epidermal growth factor receptor 2.103e-60 0.52
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 3.158e-52 0.37
FAK1_HUMAN PTK2 Focal adhesion kinase 1 1.265e-43 0.38
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 9.235e-40 0.34
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 9.914e-40 0.38
ALK_HUMAN ALK ALK tyrosine kinase receptor 6.347e-38 0.37
DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 1.557e-37 0.30
TTK_HUMAN TTK Dual specificity protein kinase TTK 3.865e-33 0.36
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 6.621e-32 0.37
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 7.683e-31 0.36
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 4.262e-22 0.37
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 9.275e-19 0.38
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.126e-18 0.30
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 3.061e-18 0.35
BCR_HUMAN BCR Breakpoint cluster region protein 7.088e-18 0.28
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.11e-16 0.39
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 3.442e-15 0.45
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 4.33e-15 0.34
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 6.106e-15 0.31
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 7.55e-15 0.38
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.11e-14 0.37
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 1.366e-14 0.31
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 1.607e-12 0.37
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 3.581e-12 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 1.311e-11 0.33
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.059e-10 0.39
GLMU_ECOLI glmU Bifunctional protein GlmU 2.736e-10 0.29
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 6.458e-10 0.35
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 8.208e-10 0.39
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 1.058e-09 0.37
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 1.684e-09 0.32
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.565e-09 0.37
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 4.669e-09 0.37
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 1.989e-08 0.34
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 2.196e-08 0.35
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 4.112e-08 0.29
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 5.172e-08 0.37
CASR_HUMAN CASR Extracellular calcium-sensing receptor 6.838e-08 0.31
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 6.842e-08 0.37
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 7.507e-08 0.33
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.597e-07 0.32
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.617e-07 0.39
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 1.915e-07 0.34
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 2.041e-07 0.29
LCK_HUMAN LCK Tyrosine-protein kinase Lck 2.178e-07 0.39
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 2.199e-07 0.31
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 3.733e-07 0.39
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.049e-07 0.39
AURKB_HUMAN AURKB Aurora kinase B 4.841e-07 0.39
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.785e-07 0.39
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.218e-06 0.39
PI2R_RAT Ptgir Prostacyclin receptor 1.53e-06 0.31
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 1.679e-06 0.37
TXK_HUMAN TXK Tyrosine-protein kinase TXK 2.597e-06 0.34
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 2.766e-06 0.37
AURKA_HUMAN AURKA Aurora kinase A 3.589e-06 0.37
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 3.727e-06 0.35
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 3.878e-06 0.37
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 5.807e-06 0.39
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 6.963e-06 0.37
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 9.9e-06 0.30

Prednisolone_acetate

CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.187e-84 0.78
ATTY_RAT Tat Tyrosine aminotransferase 1.811e-83 0.32
Q690N0_BOVIN PGR Progesterone receptor 2.094e-71 0.47
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.465e-47 0.78
GCR_MOUSE Nr3c1 Glucocorticoid receptor 7.368e-46 0.78
GCR_RAT Nr3c1 Glucocorticoid receptor 5.805e-42 0.78
SHBG_HUMAN SHBG Sex hormone-binding globulin 3.308e-40 0.54
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.27e-38 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.808e-32 0.78
CP19A_HUMAN CYP19A1 Aromatase 3.959e-25 0.46
GLNA_HUMAN GLUL Glutamine synthetase 1.488e-23 0.78
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.748e-22 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 4.155e-22 0.34
IL6_HUMAN IL6 Interleukin-6 1.155e-18 0.78
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.109e-15 0.36
NOS2_RAT Nos2 Nitric oxide synthase, inducible 2.975e-14 0.31
PRGR_RAT Pgr Progesterone receptor 3.253e-14 0.31
ANDR_RAT Ar Androgen receptor 6.939e-14 0.47
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 4.033e-13 0.34
PRGR_RABIT PGR Progesterone receptor 4.065e-13 0.32
ANDR_MOUSE Ar Androgen receptor 9.94e-10 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.143e-09 0.34
ERG2_YEAST ERG2 C-8 sterol isomerase 8.732e-08 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 2.131e-07 0.50
MCR_HUMAN NR3C2 Mineralocorticoid receptor 4.002e-07 0.78
TAT_HV112 tat Protein Tat 1.218e-06 0.29

Perfluorohexyloctane

A1ZA98_DROME Jhe Carboxylic ester hydrolase 5.543e-84 0.42
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 3.834e-73 0.42
EST5_RAT Liver carboxylesterase B-1 6.868e-69 0.32
EST1_PIG Liver carboxylesterase 7.632e-55 0.42
Q9GPG0_MANSE Carboxylic ester hydrolase 3.855e-51 0.34
PLB1_CRYNB PLB1 Phospholipase B 1.271e-44 0.30
EST1_HUMAN CES1 Liver carboxylesterase 1 3.778e-23 0.34
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.534e-20 0.33
EST2_HUMAN CES2 Cocaine esterase 1.622e-19 0.42
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 1.443e-15 0.34
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 1.371e-13 0.34
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 7.846e-13 0.33
Q197X6_TOXGO FPPS Farnesyl diphosphate synthase 1.191e-09 0.41
MGLL_MOUSE Mgll Monoglyceride lipase 1.752e-08 0.29
Q8ST54_TRYCR HK Phosphotransferase 1.848e-07 0.33
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.781e-07 0.34

Ethyl_salicylate

FOS_HUMAN FOS Proto-oncogene c-Fos 1.362e-82 0.35
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 3.297e-54 0.37
ERG1_RAT Sqle Squalene monooxygenase 9.794e-48 0.50
HIS7_ECOLI hisB Histidine biosynthesis bifunctional protein HisB 1.307e-45 0.35
JUN_HUMAN JUN Transcription factor AP-1 1.516e-45 0.35
PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 3.546e-45 0.36
I6X8D2_MYCTU pks13 Polyketide synthase Pks13 5.166e-42 0.33
MDTK_ECOLI mdtK Multidrug resistance protein MdtK 1.096e-40 0.32
MGRA_STAAU mgrA HTH-type transcriptional regulator MgrA 1.381e-38 0.31
STIM2_HUMAN STIM2 Stromal interaction molecule 2 1.102e-37 0.30
TCMO_HELTU CYP73A1 Trans-cinnamate 4-monooxygenase 1.443e-37 0.30
ENTP1_RAT Entpd1 Ectonucleoside triphosphate diphosphohydrolase 1 5.351e-37 0.29
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 3.875e-36 0.29
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.787e-35 0.45
GSTA1_HUMAN GSTA1 Glutathione S-transferase A1 9.27e-34 0.36
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 3.236e-32 0.39
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 6.528e-31 0.45
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 9.842e-31 0.35
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 4.348e-30 0.40
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 2.82e-28 0.37
BGAL_ASPNG lacA Beta-galactosidase 1.457e-27 0.34
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 8.695e-27 0.41
STXA_SHIDY stxA Shiga toxin subunit A 1.028e-26 0.37
MYOC_HUMAN MYOC Myocilin 2.362e-26 0.33
HMGB1_HUMAN HMGB1 High mobility group protein B1 5.379e-25 0.31
Q54A96_PLAFA dhod Dihydroorotate dehydrogenase 2.641e-23 0.36
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.861e-22 0.34
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 5.723e-22 0.45
EST1_RABIT Liver carboxylesterase 1 5.994e-22 0.32
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.624e-21 0.33
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.211e-21 0.55
Q4Q5W4_LEIMA Putative squalene synthase 4.944e-21 0.36
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.104e-20 0.40
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 2.515e-20 0.35
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 4.067e-20 0.32
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 4.853e-20 0.35
AA3R_HUMAN ADORA3 Adenosine receptor A3 6.684e-20 0.39
SENP7_HUMAN SENP7 Sentrin-specific protease 7 1.177e-19 0.48
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 4.884e-19 0.30
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 6.448e-19 0.40
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 8.596e-19 0.30
DUS1_MOUSE Dusp1 Dual specificity protein phosphatase 1 8.104e-18 0.28
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 1.789e-17 0.41
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.351e-17 0.33
ACRO_HUMAN ACR Acrosin 2.495e-17 0.37
CAH14_HUMAN CA14 Carbonic anhydrase 14 2.575e-17 0.65
PRTN3_HUMAN PRTN3 Myeloblastin 2.702e-17 0.43
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.11e-16 0.65
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 2.22e-16 0.55
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 3.331e-16 0.36
Q31945_CHEAL Chloroplast thylakoid membrane protein (psbA) 6.661e-16 0.30
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 1.221e-15 0.31
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.332e-15 0.39
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 3.109e-15 0.31
DOPO_HUMAN DBH Dopamine beta-hydroxylase 3.997e-15 0.30
G3PG_TRYCR Glyceraldehyde-3-phosphate dehydrogenase, glycosomal 4.441e-15 0.29
Q7ZJM1_9HIV1 pol Integrase 6.106e-15 0.38
TIM10_YEAST TIM10 Mitochondrial import inner membrane translocase subunit TIM10 1.399e-14 0.42
A0A0Y9T855_PLABE DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.421e-14 0.32
A5K1N1_PLAVS Dihydroorotate dehydrogenase, mitochondrial, putative 1.421e-14 0.32
EST2_HUMAN CES2 Cocaine esterase 1.621e-14 0.34
CLAT_RAT Chat Choline O-acetyltransferase 2.01e-14 0.33
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.964e-14 0.55
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 4.763e-14 0.40
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 6.173e-14 0.30
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 8.715e-14 0.36
KYNU_HUMAN KYNU Kynureninase 9.504e-14 0.30
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 9.781e-14 0.42
CISY2_YEAST CIT2 Citrate synthase, peroxisomal 1.107e-13 0.30
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.492e-13 0.30
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 1.529e-13 0.40
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 1.568e-13 0.30
RECA_MYCTU recA Protein RecA 1.917e-13 0.46
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 3.273e-13 0.40
PRIO_SHEEP PRNP Major prion protein 3.711e-13 0.36
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 3.922e-13 0.29
AOX_TRYBB AOX Alternative oxidase, mitochondrial 4.309e-13 0.42
AA1R_BOVIN ADORA1 Adenosine receptor A1 6.088e-13 0.35
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 6.195e-13 0.36
STRP_STRP1 ska Streptokinase A 7.22e-13 0.43
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 7.834e-13 0.31
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.414e-12 0.41
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.28e-12 0.40
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 2.419e-12 0.36
PRIO_HUMAN PRNP Major prion protein 2.451e-12 0.40
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 2.492e-12 0.33
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 3.217e-12 0.30
ALF_MYCTU fba Fructose-bisphosphate aldolase 3.468e-12 0.39
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 3.649e-12 0.55
STS_HUMAN STS Steryl-sulfatase 4.991e-12 0.39
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 1.717e-11 0.31
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.821e-11 0.65
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.418e-11 0.49
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.702e-11 0.65
HSF1_MOUSE Hsf1 Heat shock factor protein 1 2.807e-11 0.42
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 3.974e-11 0.38
ITF2_HUMAN TCF4 Transcription factor 4 4.196e-11 0.30
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 5.087e-11 0.30
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 5.402e-11 0.31
ELNE_HUMAN ELANE Neutrophil elastase 5.504e-11 0.43
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 5.539e-11 0.47
DCOR_MOUSE Odc1 Ornithine decarboxylase 5.659e-11 0.29
DNAB_MYCTU dnaB Replicative DNA helicase 6.319e-11 0.46
DYR1A_MOUSE Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.019e-11 0.31
LX15B_RAT Alox15b Arachidonate 15-lipoxygenase B 1.441e-10 0.33
P2RX4_MOUSE P2rx4 P2X purinoceptor 4 1.936e-10 0.30
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 2.41e-10 0.39
H9B8T9_CAPHI CTSB Cathepsin B 2.569e-10 0.35
LUCI_PHOPY Luciferin 4-monooxygenase 3.567e-10 0.40
Q8IL11_PLAF7 M17 leucyl aminopeptidase 4.117e-10 0.35
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.323e-10 0.32
GPR55_HUMAN GPR55 G-protein coupled receptor 55 7.824e-10 0.45
PDIA1_HUMAN P4HB Protein disulfide-isomerase 1.07e-09 0.32
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 1.171e-09 0.30
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.317e-09 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 1.543e-09 0.30
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.544e-09 0.36
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.565e-09 0.38
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.645e-09 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.763e-09 0.40
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.247e-09 0.29
ECR_BOMMO EcR Ecdysone receptor 2.487e-09 0.31
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 2.533e-09 0.29
RORA_HUMAN RORA Nuclear receptor ROR-alpha 3.108e-09 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.232e-09 0.33
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 4.127e-09 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 4.166e-09 0.36
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 4.42e-09 0.32
VGFR1_MOUSE Flt1 Vascular endothelial growth factor receptor 1 4.59e-09 0.39
MIF_HUMAN MIF Macrophage migration inhibitory factor 6.478e-09 0.43
EST1_PIG Liver carboxylesterase 6.5e-09 0.30
PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 7.176e-09 0.34
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 8.126e-09 0.31
Q8WMX0_BOVIN Muscarinic receptor M1 1.039e-08 0.30
CAH1_HUMAN CA1 Carbonic anhydrase 1 1.593e-08 0.65
DUS6_RAT Dusp6 Dual specificity protein phosphatase 6 1.715e-08 0.33
GYRB_MYCSM gyrB DNA gyrase subunit B 1.842e-08 0.34
NMT_PLAF7 Glycylpeptide N-tetradecanoyltransferase 2.163e-08 0.35
EST1_HUMAN CES1 Liver carboxylesterase 1 3.022e-08 0.32
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 3.292e-08 0.30
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 3.664e-08 0.40
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.025e-08 0.31
CAH6_HUMAN CA6 Carbonic anhydrase 6 4.084e-08 0.38
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 4.179e-08 0.43
VP16_HHV11 Tegument protein VP16 4.753e-08 0.55
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 4.835e-08 0.49
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 4.975e-08 0.33
Q8IL32_PLAF7 Heat shock protein 90, putative 5.14e-08 0.43
ILVB_ARATH ALS Acetolactate synthase, chloroplastic 5.981e-08 0.37
BGAL_HUMAN GLB1 Beta-galactosidase 6.656e-08 0.34
REV1_HUMAN REV1 DNA repair protein REV1 7.707e-08 0.29
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 8.112e-08 0.35
E3UJZ5_SPOLI Ecdysone receptor 8.262e-08 0.31
NR1D1_HUMAN NR1D1 Nuclear receptor subfamily 1 group D member 1 8.84e-08 0.33
AA1R_RAT Adora1 Adenosine receptor A1 9.987e-08 0.41
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.031e-07 0.29
Q76353_9HIV1 Integrase 1.069e-07 0.42
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 1.235e-07 0.35
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.368e-07 0.65
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 1.612e-07 0.31
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.701e-07 0.30
CAH3_BOVIN CA3 Carbonic anhydrase 3 1.788e-07 0.32
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 1.861e-07 0.35
FACE2_HUMAN RCE1 CAAX prenyl protease 2 1.864e-07 0.31
SCRB1_MOUSE Scarb1 Scavenger receptor class B member 1 2.006e-07 0.35
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 2.191e-07 0.31
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.213e-07 0.30
XBP1_HUMAN XBP1 X-box-binding protein 1 2.326e-07 0.39
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 2.36e-07 0.31
CEL_BOVIN CEL Bile salt-activated lipase 2.38e-07 0.30
SCYD_MAGO7 SDH1 Scytalone dehydratase 2.928e-07 0.35
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 3.047e-07 0.35
APAF_HUMAN APAF1 Apoptotic protease-activating factor 1 3.157e-07 0.36
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 3.203e-07 0.33
KPCA_MOUSE Prkca Protein kinase C alpha type 3.368e-07 0.32
POLG_DEN2P Genome polyprotein 3.597e-07 0.31
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 4.858e-07 0.31
CNR1_MOUSE Cnr1 Cannabinoid receptor 1 5.038e-07 0.34
CYSP_PLAFA Trophozoite cysteine proteinase 5.08e-07 0.28
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 5.365e-07 0.30
AGTRB_RAT Agtr1b Type-1B angiotensin II receptor 5.421e-07 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 5.865e-07 0.30
SOAT1_HUMAN SOAT1 Sterol O-acyltransferase 1 5.884e-07 0.30
A4_RAT App Amyloid-beta A4 protein 5.999e-07 0.30
AA1R_HUMAN ADORA1 Adenosine receptor A1 6.199e-07 0.35
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 7.62e-07 0.39
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 8.723e-07 0.45
EPHA4_MOUSE Epha4 Ephrin type-A receptor 4 8.797e-07 0.29
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 8.908e-07 0.42
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.131e-06 0.38
TLR1_MOUSE Tlr1 Toll-like receptor 1 1.184e-06 0.34
TLR2_MOUSE Tlr2 Toll-like receptor 2 1.184e-06 0.34
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.22e-06 0.41
ERR1_HUMAN ESRRA Steroid hormone receptor ERR1 1.248e-06 0.37
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.348e-06 0.40
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.388e-06 0.31
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 1.435e-06 0.40
O77240_CHOFU EcR Ecdysone receptor isoform A 1.482e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.544e-06 0.31
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.578e-06 0.33
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 1.759e-06 0.38
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.906e-06 0.30
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.947e-06 0.37
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 1.959e-06 0.29
DPOL_VACCW POL DNA polymerase 2.128e-06 0.31
TPA_HUMAN PLAT Tissue-type plasminogen activator 2.605e-06 0.38
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 2.652e-06 0.42
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 2.863e-06 0.30
CAH13_MOUSE Ca13 Carbonic anhydrase 13 3.157e-06 0.38
NSD2_HUMAN NSD2 Histone-lysine N-methyltransferase NSD2 3.239e-06 0.39
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 3.325e-06 0.39
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 3.37e-06 0.35
NORA_STAAU norA Quinolone resistance protein NorA 3.558e-06 0.30
PTGES_HUMAN PTGES Prostaglandin E synthase 3.563e-06 0.39
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 3.628e-06 0.31
SENP6_HUMAN SENP6 Sentrin-specific protease 6 3.851e-06 0.37
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.998e-06 0.38
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.596e-06 0.29
TNFA_HUMAN TNF Tumor necrosis factor 4.616e-06 0.42
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 4.685e-06 0.31
PPBT_HUMAN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 4.935e-06 0.38
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 5.557e-06 0.29
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 6.348e-06 0.38
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 7.048e-06 0.55
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 7.317e-06 0.31
TYDP2_HUMAN TDP2 Tyrosyl-DNA phosphodiesterase 2 7.586e-06 0.39
AGP1_YEAST AGP1 General amino acid permease AGP1 7.953e-06 0.28
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 7.953e-06 0.38
RL19A_YEAST RPL19A 60S ribosomal protein L19-A 8.333e-06 0.29
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 9.375e-06 0.34

L-Acetylleucine

RIR1_HHV11 RIR1 Ribonucleoside-diphosphate reductase large subunit 1.564e-79 0.45
NEP_MOUSE Mme Neprilysin 2.965e-72 0.49
GSP_CRIFA GSP Glutathionylspermidine synthase 1.247e-70 0.41
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.098e-69 0.40
GNPAT_HUMAN GNPAT Dihydroxyacetone phosphate acyltransferase 5.645e-65 0.41
AMPN_PIG ANPEP Aminopeptidase N 2.063e-63 0.46
CATB_BOVIN CTSB Cathepsin B 3.257e-62 0.43
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 6.006e-62 0.40
ST14_MOUSE St14 Suppressor of tumorigenicity 14 protein homolog 3.12e-60 0.33
CAN2_BOVIN CAPN2 Calpain-2 catalytic subunit 1.715e-57 0.32
AMPB_MOUSE Rnpep Aminopeptidase B 4.714e-55 0.44
AMPL_BOVIN LAP3 Cytosol aminopeptidase 4.714e-55 0.44
PLMN_BOVIN PLG Plasminogen 2.766e-54 0.39
THER_BACTH npr Thermolysin 3.072e-54 0.35
AMPL_HUMAN LAP3 Cytosol aminopeptidase 3.744e-51 0.56
CAN1_HUMAN CAPN1 Calpain-1 catalytic subunit 6.196e-51 0.62
AMPB_HUMAN RNPEP Aminopeptidase B 1.815e-50 0.43
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 3.479e-50 0.44
EDNRB_RAT Ednrb Endothelin receptor type B 8.345e-50 0.38
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 9.972e-46 0.41
CFAB_HUMAN CFB Complement factor B 3.591e-45 0.49
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 5.079e-45 0.54
CO2_HUMAN C2 Complement C2 1.968e-44 0.35
AMPX_VIBPR Bacterial leucyl aminopeptidase 6.698e-44 0.44
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 2.98e-42 0.48
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 3.909e-42 0.34
Q6DMN0_TOXGO CPL Cathepsin L 1.602e-41 0.36
VM1B1_BOTAS Snake venom metalloproteinase BaP1 3.13e-40 0.36
CBPA1_BOVIN CPA1 Carboxypeptidase A1 9.716e-39 0.42
SPSB2_HUMAN SPSB2 SPRY domain-containing SOCS box protein 2 1.243e-38 0.33
POLG_HRV14 Genome polyprotein 1.102e-37 0.30
AMPN_MOUSE Anpep Aminopeptidase N 1.629e-37 0.44
AMPN_HUMAN ANPEP Aminopeptidase N 4.633e-37 0.44
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.23e-36 0.52
Q6UB75_PIG Group VII phospholipase A2 1.041e-34 0.33
NRAM_INBLE Neuraminidase 9.974e-33 0.38
PAPA1_CARPA Papain 1.153e-32 0.36
Q95WR6_LEIDO Cysteine protease 1.49e-31 0.39
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 1.069e-29 0.29
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 3.008e-29 0.56
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 4.718e-29 0.42
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 5.812e-29 0.37
AMPB_RAT Rnpep Aminopeptidase B 1.329e-28 0.44
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 3.955e-28 0.62
MMP8_RAT Mmp8 Neutrophil collagenase 4.06e-28 0.32
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 3.617e-27 0.39
HEPS_HUMAN HPN Serine protease hepsin 1.174e-26 0.41
ACE_MOUSE Ace Angiotensin-converting enzyme 3.524e-26 0.44
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 3.773e-26 0.33
CPNS1_PIG CAPNS1 Calpain small subunit 1 6.2e-26 0.33
GGH_HUMAN GGH Gamma-glutamyl hydrolase 3.516e-24 0.30
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 1.771e-23 0.43
Q9NAW4_PLAFA Cysteine protease falcipain-3 4.234e-23 0.39
NEP_RABIT MME Neprilysin 1.022e-22 0.37
NEP_PIG MME Neprilysin 2.443e-22 0.37
NRAM_I34A1 Neuraminidase 1.399e-21 0.38
MMP3_HUMAN MMP3 Stromelysin-1 1.434e-20 0.37
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 2.103e-20 0.42
AMP1_PLAFQ M1 family aminopeptidase 2.957e-18 0.47
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 3.488e-18 0.29
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 3.488e-18 0.29
AMPN_ECOLI pepN Aminopeptidase N 4.879e-18 0.29
NEP_HUMAN MME Neprilysin 8.96e-18 0.46
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.882e-17 0.33
PA2G5_HUMAN PLA2G5 Calcium-dependent phospholipase A2 4.449e-17 0.50
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.11e-16 0.29
NEP_RAT Mme Neprilysin 3.331e-16 0.46
ACE_HUMAN ACE Angiotensin-converting enzyme 7.772e-16 0.39
EDNRA_HUMAN EDNRA Endothelin-1 receptor 1.776e-15 0.36
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.998e-15 0.29
FURIN_HUMAN FURIN Furin 2.331e-15 0.40
CAN1_PIG CAPN1 Calpain-1 catalytic subunit 2.442e-15 0.45
MMP1_HUMAN MMP1 Interstitial collagenase 3.331e-15 0.41
AMPL_PIG LAP3 Cytosol aminopeptidase 6.661e-15 0.30
Q8I6Z5_PLAF7 Plasmepsin V 1.477e-14 0.31
CATL1_BOVIN CTSL Cathepsin L1 1.765e-14 0.36
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 2.121e-14 0.37
KISSR_HUMAN KISS1R KiSS-1 receptor 7.028e-14 0.45
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.323e-13 0.29
Q9I056_PSEAE cpg2 Carboxypeptidase G2 1.492e-13 0.30
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 3.922e-13 0.29
CATK_HUMAN CTSK Cathepsin K 4.55e-13 0.39
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 8.417e-13 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 8.417e-13 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 8.417e-13 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 8.417e-13 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 8.417e-13 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 8.417e-13 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 8.417e-13 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 8.417e-13 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 8.417e-13 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 8.417e-13 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 8.417e-13 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 8.417e-13 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 8.417e-13 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 8.417e-13 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 8.417e-13 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 8.417e-13 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 8.417e-13 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 8.417e-13 0.30
CATH_HUMAN CTSH Pro-cathepsin H 1.364e-12 0.39
PGTB1_HUMAN PGGT1B Geranylgeranyl transferase type-1 subunit beta 2.151e-12 0.33
NK3R_CAVPO TACR3 Neuromedin-K receptor 2.155e-12 0.31
MMP9_RAT Mmp9 Matrix metalloproteinase-9 2.279e-12 0.32
CATB_HUMAN CTSB Cathepsin B 2.444e-12 0.62
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 2.682e-12 0.50
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 8.776e-12 0.35
Q9NBA7_PLAFA Cysteine protease falcipain-3 1.309e-11 0.31
CATL1_HUMAN CTSL Cathepsin L1 1.361e-11 0.40
CHIA_SERMA chiA Chitinase A 1.391e-11 0.34
R1AB_SARS rep Replicase polyprotein 1ab 1.483e-11 0.42
Q95PM0_TRYBR rhodesain Cysteine protease 1.926e-11 0.33
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 2.029e-11 0.34
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 2.029e-11 0.34
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 2.029e-11 0.34
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 2.029e-11 0.34
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 2.029e-11 0.34
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 2.029e-11 0.34
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 2.029e-11 0.34
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 2.029e-11 0.34
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 2.029e-11 0.34
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 2.029e-11 0.34
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 2.029e-11 0.34
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 2.029e-11 0.34
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 2.029e-11 0.34
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 2.949e-11 0.50
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 3.176e-11 0.30
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 4.615e-11 0.34
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 1.151e-10 0.37
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.09e-10 0.44
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 2.874e-10 0.28
CATK_RABIT CTSK Cathepsin K 3.505e-10 0.32
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 5.297e-10 0.38
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 5.445e-10 0.40
CBX7_HUMAN CBX7 Chromobox protein homolog 7 5.673e-10 0.32
AMPE_HUMAN ENPEP Glutamyl aminopeptidase 8.153e-10 0.38
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.221e-09 0.34
SF3B3_HUMAN SF3B3 Splicing factor 3B subunit 3 1.597e-09 0.34
Q4U254_9ENTO protease Protease 1.838e-09 0.37
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 2.112e-09 0.34
POLG_HCV1 Genome polyprotein 2.276e-09 0.32
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.557e-09 0.38
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 2.73e-09 0.33
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 3.061e-09 0.44
NK2R_MESAU TACR2 Substance-K receptor 7.697e-09 0.31
O07911_STAAU agrC AgrC 9.257e-09 0.31
MMP2_HUMAN MMP2 72 kDa type IV collagenase 9.805e-09 0.44
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 1.006e-08 0.33
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 1.322e-08 0.29
NTR2_RAT Ntsr2 Neurotensin receptor type 2 3.613e-08 0.31
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 3.614e-08 0.39
SPP2A_HUMAN SPPL2A Signal peptide peptidase-like 2A 5.69e-08 0.31
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 5.88e-08 0.34
DCOR_HUMAN ODC1 Ornithine decarboxylase 6.44e-08 0.29
CATS_HUMAN CTSS Cathepsin S 6.826e-08 0.38
CBPA1_HUMAN CPA1 Carboxypeptidase A1 6.976e-08 0.35
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 7.294e-08 0.39
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 1.236e-07 0.34
A3EZI9_9HEPC NS3 Genome polyprotein 1.388e-07 0.40
GRIK2_RAT Grik2 Glutamate receptor ionotropic, kainate 2 1.692e-07 0.37
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.651e-07 0.30
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 3.244e-07 0.31
WDR5_HUMAN WDR5 WD repeat-containing protein 5 4.721e-07 0.32
AMD_RAT Pam Peptidylglycine alpha-amidating monooxygenase 8.033e-07 0.36
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.195e-06 0.29
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.35e-06 0.37
H9B8T9_CAPHI CTSB Cathepsin B 1.356e-06 0.39
GRIK1_RAT Grik1 Glutamate receptor ionotropic, kainate 1 2.186e-06 0.37
ACE_RABIT ACE Angiotensin-converting enzyme 2.199e-06 0.46
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 5.463e-06 0.28
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 6.14e-06 0.33
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 6.167e-06 0.39
CAN1_RAT Capn1 Calpain-1 catalytic subunit 7.112e-06 0.29
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 9.449e-06 0.31

Alloin

SC5A2_HUMAN SLC5A2 Sodium/glucose cotransporter 2 6.285e-78 0.39
FIMH_ECOLI fimH Type 1 fimbrin D-mannose specific adhesin 2.325e-76 0.34
AL1A7_RAT Aldh1a7 Aldehyde dehydrogenase, cytosolic 1 1.898e-75 0.50
ALDH2_RAT Aldh2 Aldehyde dehydrogenase, mitochondrial 1.414e-62 0.50
Q9BEG3_BOVIN 5-lipoxygenase 2.802e-59 0.42
CDD_MOUSE Cda Cytidine deaminase 9.069e-54 0.33
LOX12_MOUSE Alox12 Arachidonate 12-lipoxygenase, 12S-type 1.525e-46 0.32
TOP1_MOUSE Top1 DNA topoisomerase 1 2.116e-40 0.31
RASN_HUMAN NRAS GTPase NRas 3.17e-38 0.30
S28A3_HUMAN SLC28A3 Solute carrier family 28 member 3 6.694e-38 0.30
CDD_HUMAN CDA Cytidine deaminase 4.924e-36 0.33
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 6.252e-36 0.34
FAS_CHICK FASN Fatty acid synthase 6.705e-36 0.28
B4EH87_BURCJ Lectin 4.423e-31 0.31
MALX3_YEAST IMA1 Oligo-1,6-glucosidase IMA1 3.303e-30 0.30
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 5.891e-27 0.34
ADA_MOUSE Ada Adenosine deaminase 1.481e-26 0.33
SC5AB_HUMAN SLC5A11 Sodium/myo-inositol cotransporter 2 5.889e-23 0.28
TOP1_HUMAN TOP1 DNA topoisomerase 1 2.074e-21 0.36
SC5A2_RAT Slc5a2 Sodium/glucose cotransporter 2 2.998e-15 0.31
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 4.441e-15 0.29
TYRO_HUMAN TYR Tyrosinase 7.883e-15 0.31
AGRA_STAAU agrA Accessory gene regulator protein A 1.599e-14 0.36
RASH_HUMAN HRAS GTPase HRas 3.603e-13 0.36
CAH12_HUMAN CA12 Carbonic anhydrase 12 6.104e-13 0.36
SC5A4_HUMAN SLC5A4 Solute carrier family 5 member 4 9.895e-13 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 4.064e-12 0.36
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 9.7e-12 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 1.334e-11 0.36
SC5A1_RAT Slc5a1 Sodium/glucose cotransporter 1 9.374e-11 0.31
IL2_HUMAN IL2 Interleukin-2 1.176e-10 0.30
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 6.538e-10 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 8.829e-10 0.36
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 3.152e-09 0.29
IL6_HUMAN IL6 Interleukin-6 3.482e-09 0.37
G6PT1_HUMAN SLC37A4 Glucose-6-phosphate exchanger SLC37A4 5.367e-09 0.30
O96394_LEIAM Arginase 6.365e-09 0.30
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.153e-08 0.29
TNNC1_HUMAN TNNC1 Troponin C, slow skeletal and cardiac muscles 3.642e-08 0.54
TNNI3_HUMAN TNNI3 Troponin I, cardiac muscle 3.642e-08 0.54
TNNT2_HUMAN TNNT2 Troponin T, cardiac muscle 3.642e-08 0.54
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.855e-08 0.36
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.017e-07 0.30
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 1.849e-07 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.396e-07 0.29
CAH13_HUMAN CA13 Carbonic anhydrase 13 6.368e-07 0.35
PDIA1_HUMAN P4HB Protein disulfide-isomerase 8.02e-07 0.31
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 2.836e-06 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 3.716e-06 0.31
HKDC1_HUMAN HKDC1 Hexokinase HKDC1 5.025e-06 0.54
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 5.03e-06 0.30
IL5_MOUSE Il5 Interleukin-5 8.365e-06 0.30

Fosdenopterin

Q9HX69_PSEAE rocR RocR 5.998e-76 0.40
E1BN64_BOVIN PDE3B Phosphodiesterase 7.17e-11 0.37

Cinoxate

GP183_MOUSE Gpr183 G-protein coupled receptor 183 1.566e-75 0.42
AHR_RABIT AHR Aryl hydrocarbon receptor 4.529e-67 0.40
O93874_COCLU 17HSDcl 17beta-hydroxysteroid dehydrogenase 5.564e-66 0.40
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 5.882e-54 0.33
GP183_HUMAN GPR183 G-protein coupled receptor 183 7.018e-50 0.42
CYSP_PLAFA Trophozoite cysteine proteinase 1.544e-49 0.46
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 2.536e-44 0.39
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 3.353e-41 0.47
ACH10_HUMAN CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 3.56e-37 0.29
ACHA9_HUMAN CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 3.56e-37 0.29
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 9.833e-36 0.39
TAU_HUMAN MAPT Microtubule-associated protein tau 2.672e-35 0.39
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 6.836e-35 0.40
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 2.527e-33 0.48
A4_HUMAN APP Amyloid-beta precursor protein 2.749e-32 0.45
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.57e-31 0.47
MTSI_SPISQ sssIM CPG DNA methylase 1.115e-30 0.35
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.438e-30 0.45
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 1.077e-24 0.46
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 4.357e-24 0.46
CAH13_MOUSE Ca13 Carbonic anhydrase 13 1.626e-23 0.45
Q86PR3_AEDAE SCP-2 Sterol carrier protein 2 4.633e-23 0.28
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 1.828e-22 0.35
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.427e-22 0.50
TF65_HUMAN RELA Transcription factor p65 1.474e-21 0.40
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 2.349e-21 0.50
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 3.215e-21 0.36
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 3.406e-19 0.50
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 2.824e-18 0.36
LT4R1_HUMAN LTB4R Leukotriene B4 receptor 1 5.783e-18 0.37
KLK14_HUMAN KLK14 Kallikrein-14 7.088e-18 0.28
Q7ZJM1_9HIV1 pol Integrase 4.32e-17 0.49
MEP1B_HUMAN MEP1B Meprin A subunit beta 1.11e-16 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.11e-16 0.44
LGUL_HUMAN GLO1 Lactoylglutathione lyase 4.441e-16 0.35
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 4.441e-16 0.34
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.551e-16 0.54
CRTN_STAAW crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 1.887e-15 0.29
ESR1_HUMAN ESR1 Estrogen receptor 5.44e-15 0.42
TNR1A_HUMAN TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1.066e-14 0.45
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.032e-14 0.49
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 4.419e-14 0.35
MMP1_HUMAN MMP1 Interstitial collagenase 6.295e-14 0.44
P90584_PLAFA Pfmrk MO15-related protein kinase Pfmrk 7.86e-14 0.43
DXR_ECOLI dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8.127e-14 0.31
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.204e-13 0.44
CAH7_HUMAN CA7 Carbonic anhydrase 7 3.285e-13 0.54
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 6.973e-13 0.34
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.291e-12 0.48
STXA_SHIDY stxA Shiga toxin subunit A 1.6e-12 0.46
HDAC1_HUMAN HDAC1 Histone deacetylase 1 2.219e-12 0.48
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.308e-12 0.36
TLR4_MOUSE Tlr4 Toll-like receptor 4 4.817e-12 0.40
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 6.661e-12 0.43
HDAC1_MOUSE Hdac1 Histone deacetylase 1 1.057e-11 0.30
H9B8T9_CAPHI CTSB Cathepsin B 1.062e-11 0.37
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.371e-11 0.44
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.852e-11 0.39
CAH9_HUMAN CA9 Carbonic anhydrase 9 3.523e-11 0.54
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 4.31e-11 0.36
FOS_HUMAN FOS Proto-oncogene c-Fos 4.317e-11 0.38
RBBP9_HUMAN RBBP9 Serine hydrolase RBBP9 4.757e-11 0.30
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.865e-11 0.36
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 5.096e-11 0.29
AHR_HUMAN AHR Aryl hydrocarbon receptor 5.901e-11 0.40
P2RX1_MOUSE P2rx1 P2X purinoceptor 1 9.421e-11 0.34
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 1.12e-10 0.47
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 1.122e-10 0.29
CAH12_HUMAN CA12 Carbonic anhydrase 12 2.237e-10 0.54
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 2.276e-10 0.37
CRTN_STAAM crtN 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 4.398e-10 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 5.69e-10 0.40
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 5.944e-10 0.33
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 7.916e-10 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 8.307e-10 0.41
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 8.321e-10 0.37
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 8.589e-10 0.30
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.274e-09 0.37
JUN_HUMAN JUN Transcription factor AP-1 1.702e-09 0.38
CAH1_HUMAN CA1 Carbonic anhydrase 1 4.632e-09 0.54
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 5.783e-09 0.42
CALM1_HUMAN CALM1 Calmodulin-1 2.8e-08 0.29
Q49PX0_9POXV N1L N1L 2.8e-08 0.29
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.288e-08 0.31
CAH3_HUMAN CA3 Carbonic anhydrase 3 7.64e-08 0.33
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.887e-08 0.39
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 7.986e-08 0.31
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 9.002e-08 0.29
MMP13_HUMAN MMP13 Collagenase 3 1.089e-07 0.36
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.096e-07 0.39
EST1_RABIT Liver carboxylesterase 1 1.166e-07 0.36
Q4U254_9ENTO protease Protease 1.184e-07 0.38
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.323e-07 0.35
EXSA_PSEAE exsA Exoenzyme S synthesis regulatory protein ExsA 1.384e-07 0.30
HPSE_HUMAN HPSE Heparanase 1.411e-07 0.32
G6PC_HUMAN G6PC Glucose-6-phosphatase 2.041e-07 0.29
PA_I34A1 PA Polymerase acidic protein 2.225e-07 0.32
AOC3_HUMAN AOC3 Membrane primary amine oxidase 2.26e-07 0.32
ODP2_MYCTU dlaT Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 2.36e-07 0.31
ACES_ELEEL ache Acetylcholinesterase 2.467e-07 0.51
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.825e-07 0.49
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 2.857e-07 0.38
Q9ZTP8_MAIZE hd1b Histone deacetylase 2.879e-07 0.37
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.372e-07 0.41
CLAT_RAT Chat Choline O-acetyltransferase 3.374e-07 0.29
POLG_DEN2P Genome polyprotein 3.68e-07 0.31
CAH2_HUMAN CA2 Carbonic anhydrase 2 4.276e-07 0.54
CAH4_HUMAN CA4 Carbonic anhydrase 4 4.312e-07 0.50
CP26B_HUMAN CYP26B1 Cytochrome P450 26B1 4.339e-07 0.29
AMPN_HUMAN ANPEP Aminopeptidase N 5.055e-07 0.35
NORA_STAAU norA Quinolone resistance protein NorA 5.191e-07 0.34
HDAC8_HUMAN HDAC8 Histone deacetylase 8 6.509e-07 0.48
DXR_MYCTU dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6.6e-07 0.31
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 8.676e-07 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 1.046e-06 0.41
LYAG_RAT Gaa Lysosomal alpha-glucosidase 1.237e-06 0.38
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.241e-06 0.30
TOP2A_HUMAN TOP2A DNA topoisomerase 2-alpha 1.368e-06 0.33
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.545e-06 0.48
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 2.083e-06 0.35
TF_HUMAN F3 Tissue factor 2.141e-06 0.55
TTHY_HUMAN TTR Transthyretin 2.311e-06 0.45
MMP3_HUMAN MMP3 Stromelysin-1 2.372e-06 0.35
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 2.492e-06 0.36
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.99e-06 0.29
OXDA_MOUSE Dao D-amino-acid oxidase 3.203e-06 0.29
MMP12_HUMAN MMP12 Macrophage metalloelastase 3.212e-06 0.33
KLK5_HUMAN KLK5 Kallikrein-5 3.213e-06 0.28
HCAR2_HUMAN HCAR2 Hydroxycarboxylic acid receptor 2 3.582e-06 0.35
NR1H4_HUMAN NR1H4 Bile acid receptor 3.685e-06 0.36
ESR2_HUMAN ESR2 Estrogen receptor beta 3.719e-06 0.42
BACE1_HUMAN BACE1 Beta-secretase 1 4.645e-06 0.56
MMP2_HUMAN MMP2 72 kDa type IV collagenase 5.582e-06 0.44
KPCA_MOUSE Prkca Protein kinase C alpha type 5.924e-06 0.30
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 7.101e-06 0.36
A0A060INS8_CAPHI CTSH Cathepsin H 7.911e-06 0.36
O49150_SOLTU Lipoxygenase 8.09e-06 0.28
SENP7_HUMAN SENP7 Sentrin-specific protease 7 9.676e-06 0.52
MET_HUMAN MET Hepatocyte growth factor receptor 9.679e-06 0.47

Deucravacitinib

O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 4.802e-75 0.32
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 1.112e-29 0.37
ST17B_HUMAN STK17B Serine/threonine-protein kinase 17B 5.978e-25 0.31
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 3.841e-14 0.35
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.421e-13 0.33
TTK_HUMAN TTK Dual specificity protein kinase TTK 1.518e-11 0.34
NTR2_RAT Ntsr2 Neurotensin receptor type 2 5.485e-11 0.29
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 6.98e-10 0.32
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 7.629e-10 0.36
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 3.71e-09 0.35
SC5A1_HUMAN SLC5A1 Sodium/glucose cotransporter 1 3.721e-09 0.30
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 2.783e-08 0.30
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 5.503e-08 0.33
RXFP1_HUMAN RXFP1 Relaxin receptor 1 1.106e-07 0.29
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 4.25e-07 0.32
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 4.436e-07 0.34
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 9.341e-07 0.30
DRD3_RAT Drd3 D(3) dopamine receptor 1.835e-06 0.31
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 1.985e-06 0.29
WNT3_HUMAN WNT3 Proto-oncogene Wnt-3 3.546e-06 0.32
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 5.135e-06 0.33
CDK3_HUMAN CDK3 Cyclin-dependent kinase 3 6.618e-06 0.30

Pirtobrutinib

Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 1.057e-74 0.38
CARM1_MOUSE Carm1 Histone-arginine methyltransferase CARM1 2.71e-65 0.35
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 3.891e-40 0.31
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 1.424e-37 0.35
Q8MMZ4_PLAFA cGMP-dependent protein kinase 2.562e-37 0.33
DRD2_CANLF DRD2 D(2) dopamine receptor 3.56e-37 0.29
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 1.068e-34 0.31
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 2.22e-34 0.38
Q76353_9HIV1 Integrase 2.841e-33 0.35
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.764e-25 0.36
HDAC1_MOUSE Hdac1 Histone deacetylase 1 5.602e-24 0.34
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 6.404e-24 0.45
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 7.6e-23 0.45
PPGB_HUMAN CTSA Lysosomal protective protein 9.468e-23 0.33
MMP13_MOUSE Mmp13 Collagenase 3 4.885e-15 0.30
XPA_HUMAN XPA DNA repair protein complementing XP-A cells 1.354e-14 0.31
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.743e-14 0.36
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 2.187e-14 0.38
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 7.472e-14 0.35
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 1.814e-13 0.38
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 4.553e-13 0.28
GLR_HUMAN GCGR Glucagon receptor 4.662e-13 0.33
RNT1_ASPOR rntA Guanyl-specific ribonuclease T1 6.325e-13 0.28
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 6.983e-13 0.32
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.11e-12 0.42
Q7ZJM1_9HIV1 pol Integrase 2.047e-12 0.33
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 7.384e-12 0.36
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 1.102e-11 0.28
ELNE_HUMAN ELANE Neutrophil elastase 1.402e-11 0.33
STABP_HUMAN STAMBP STAM-binding protein 4.795e-11 0.30
RENI_CALJA REN Renin 7.729e-11 0.29
PPARD_MOUSE Ppard Peroxisome proliferator-activated receptor delta 1.055e-10 0.38
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1.245e-10 0.28
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.257e-10 0.28
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 1.365e-10 0.38
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 1.427e-10 0.30
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 4.015e-09 0.28
SYK_HUMAN KARS1 Lysine--tRNA ligase 4.312e-09 0.31
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 4.601e-09 0.32
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 8.515e-09 0.29
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.791e-08 0.28
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 2.699e-08 0.31
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 4.73e-08 0.32
PI4KB_HUMAN PI4KB Phosphatidylinositol 4-kinase beta 4.756e-08 0.31
HCK_HUMAN HCK Tyrosine-protein kinase HCK 6.375e-08 0.31
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 9.778e-08 0.33
OX2R_HUMAN HCRTR2 Orexin receptor type 2 1.069e-07 0.40
BKRB1_HUMAN BDKRB1 B1 bradykinin receptor 2.132e-07 0.35
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.612e-07 0.33
KPCZ_HUMAN PRKCZ Protein kinase C zeta type 2.958e-07 0.34
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 3.01e-07 0.33
HMDH_RAT Hmgcr 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3.011e-07 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.205e-07 0.29
MMEL1_HUMAN MMEL1 Membrane metallo-endopeptidase-like 1 3.903e-07 0.32
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 5.289e-07 0.31
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 8.107e-07 0.29
GPR52_HUMAN GPR52 G-protein coupled receptor 52 8.878e-07 0.32
GALR3_HUMAN GALR3 Galanin receptor type 3 1.171e-06 0.33
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 1.762e-06 0.35
DPOL_HCMVA UL54 DNA polymerase catalytic subunit 1.782e-06 0.30
KC1E_HUMAN CSNK1E Casein kinase I isoform epsilon 1.947e-06 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 2.683e-06 0.39
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.203e-06 0.29
OX1R_HUMAN HCRTR1 Orexin receptor type 1 3.482e-06 0.40
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 5.875e-06 0.29
FACE2_HUMAN RCE1 CAAX prenyl protease 2 6.35e-06 0.32
PASK_HUMAN PASK PAS domain-containing serine/threonine-protein kinase 6.678e-06 0.29
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 6.902e-06 0.38
MMP13_HUMAN MMP13 Collagenase 3 8.055e-06 0.33
KIFC1_HUMAN KIFC1 Kinesin-like protein KIFC1 8.364e-06 0.29

Laurocapram

GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 5.562e-74 0.35
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 2.463e-72 0.35
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 8.027e-68 0.37
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 4.713e-43 0.30
EST5_RAT Liver carboxylesterase B-1 4.385e-32 0.29
PPCE_RAT Prep Prolyl endopeptidase 2.291e-27 0.31
FSHR_HUMAN FSHR Follicle-stimulating hormone receptor 2.474e-24 0.33
SPHK2_MOUSE Sphk2 Sphingosine kinase 2 1.848e-23 0.29
Q9GPG0_MANSE Carboxylic ester hydrolase 2.847e-23 0.29
SOAT1_CHLAE SOAT1 Sterol O-acyltransferase 1 5.277e-21 0.35
MGLL_RAT Mgll Monoglyceride lipase 1.203e-19 0.45
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.331e-16 0.31
SOAT2_CHLAE SOAT2 Sterol O-acyltransferase 2 3.331e-16 0.35
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 1.665e-15 0.35
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 5.329e-15 0.31
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 2.431e-14 0.31
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 5.973e-14 0.31
LASR_PSEAE lasR Transcriptional activator protein LasR 6.487e-13 0.33
B6TK44_MAIZE Cycloeucalenol cycloisomerase 2.757e-12 0.30
EST2C_MOUSE Ces2c Acylcarnitine hydrolase 9.7e-12 0.29
MEP2_YEAST MEP2 Ammonium transporter MEP2 1.29e-11 0.34
EST1_PIG Liver carboxylesterase 2.773e-11 0.29
Q2TU57_MAIZE Sterol-8,7-isomerase 3.542e-11 0.30
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.415e-10 0.28
LSS_RAT Lss Lanosterol synthase 7.773e-10 0.33
EST1_RABIT Liver carboxylesterase 1 1.095e-09 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 1.457e-09 0.34
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.615e-09 0.31
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 3.344e-09 0.41
A1ZA98_DROME Jhe Carboxylic ester hydrolase 3.598e-09 0.29
EST1_HUMAN CES1 Liver carboxylesterase 1 5.489e-09 0.31
MGLL_HUMAN MGLL Monoglyceride lipase 1.327e-08 0.45
INMT_HUMAN INMT Indolethylamine N-methyltransferase 1.485e-08 0.37
CAN2_PIG CAPN2 Calpain-2 catalytic subunit 1.776e-08 0.38
HDAC6_MOUSE Hdac6 Histone deacetylase 6 2.17e-08 0.29
O07911_STAAU agrC AgrC 3.301e-08 0.29
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 5.317e-08 0.36
EST2_HUMAN CES2 Cocaine esterase 7.234e-08 0.29
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 7.986e-08 0.31
MTR1B_CHICK Melatonin receptor type 1B 8.323e-08 0.32
ASAH1_RAT Asah1 Acid ceramidase 8.691e-08 0.29
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 1.227e-07 0.28
LUXR_ALIFS luxR Transcriptional activator protein LuxR 2.769e-07 0.30
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 2.972e-07 0.30
DPOLB_RAT Polb DNA polymerase beta 4.537e-07 0.34
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 8.113e-07 0.32
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.24e-06 0.29
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 4.54e-06 0.32
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 5.035e-06 0.41
MPIP2_MOUSE Cdc25b M-phase inducer phosphatase 2 6.235e-06 0.29
ICMT_HUMAN ICMT Protein-S-isoprenylcysteine O-methyltransferase 6.761e-06 0.31
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.112e-06 0.29
SOAT2_HUMAN SOAT2 Sterol O-acyltransferase 2 7.713e-06 0.35

Paltusotine

MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 2.445e-67 0.49
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.11e-16 0.43
FKB1B_HUMAN FKBP1B Peptidyl-prolyl cis-trans isomerase FKBP1B 3.664e-15 0.29
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.432e-08 0.41
PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.848e-07 0.33

Zoledronate_D_L-Lysine_Monohydrate

GLN1B_ECOLI glnA Glutamine synthetase 1.036e-66 0.33
GRM8_MOUSE Grm8 Metabotropic glutamate receptor 8 2.281e-40 0.32
OTC_HUMAN OTC Ornithine carbamoyltransferase, mitochondrial 7.545e-40 0.32
ARGI1_HUMAN ARG1 Arginase-1 6.58e-28 0.34
GRM8_RAT Grm8 Metabotropic glutamate receptor 8 1.052e-27 0.32
ISPA_ECOLI ispA Farnesyl diphosphate synthase 1.124e-26 0.60
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 7.498e-24 0.29
GRM6_RAT Grm6 Metabotropic glutamate receptor 6 2.309e-22 0.32
BT3A1_HUMAN BTN3A1 Butyrophilin subfamily 3 member A1 1.493e-21 0.60
THAS_HUMAN TBXAS1 Thromboxane-A synthase 2.673e-20 0.42
GGPPS_YEAST BTS1 Geranylgeranyl pyrophosphate synthase 8.254e-20 0.60
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 5.551e-16 0.60
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 3.109e-15 0.60
AMPB_RAT Rnpep Aminopeptidase B 1.099e-14 0.33
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.272e-13 0.32
Q8ST54_TRYCR HK Phosphotransferase 1.983e-13 0.33
AMPB_HUMAN RNPEP Aminopeptidase B 5.659e-11 0.29
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 3.607e-10 0.37
THAS_RAT Tbxas1 Thromboxane-A synthase 8.792e-10 0.30
BHMT1_HUMAN BHMT Betaine--homocysteine S-methyltransferase 1 4.778e-08 0.32
O31048_PORGN DPP IV Dipeptidyl peptidase IV 1.463e-07 0.30
CBPB1_HUMAN CPB1 Carboxypeptidase B 1.591e-06 0.31
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 2.993e-06 0.32
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 4.124e-06 0.32

Indocyanine_green

S22A7_RAT Slc22a7 Solute carrier family 22 member 7 3.2e-66 0.83
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 5.284e-32 0.71
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.56e-17 0.83
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 1.821e-09 0.66

Gadopiclenol

MEP50_HUMAN WDR77 Methylosome protein 50 4.517e-65 0.35
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 5.03e-65 0.35

Ziftomenib

MEN1_MOUSE Men1 Menin 1.414e-62 0.50
MEN1_HUMAN MEN1 Menin 3.809e-18 0.56
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 6.159e-07 0.34

Pafolacianine

Q81VW8_BACAN folP Dihydropteroate synthase 9.07e-58 0.35
DYR_MOUSE Dhfr Dihydrofolate reductase 1.215e-37 0.30
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 1.604e-29 0.30
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 4.628e-24 0.30
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 2.516e-22 0.39
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 7.459e-19 0.30
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 2.844e-12 0.32
E2QDN0_ECOLX thyA Thymidylate synthase 1.398e-10 0.28
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 1.954e-10 0.30
DYR_HUMAN DHFR Dihydrofolate reductase 2.148e-10 0.36
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 1.055e-06 0.30

Foscarbidopa

STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 5.181e-57 0.33
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 3.768e-46 0.33
SCMU_MYCTU Secreted chorismate mutase 2.223e-37 0.30
DDC_MOUSE Ddc Aromatic-L-amino-acid decarboxylase 7.142e-37 0.29
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 1.019e-28 0.38
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 8.971e-25 0.33
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 4.414e-24 0.36
SO1C1_MOUSE Slco1c1 Solute carrier organic anion transporter family member 1C1 5.245e-24 0.30
FABI_ECOLI fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 2.635e-22 0.34
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.809e-19 0.30
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 8.882e-16 0.32
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 2.343e-13 0.29
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 4.998e-13 0.31
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 2.177e-12 0.67
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 2.334e-12 0.30
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.492e-12 0.33
T1QYY3_9HIV1 int Integrase 3.048e-11 0.30
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 3.454e-11 0.38
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 3.267e-09 0.30
Q965D5_PLAFA fabI Enoyl-acyl-carrier protein reductase 2.475e-08 0.30
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.07e-07 0.32
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 2.021e-06 0.33
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 4.532e-06 0.30
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 4.532e-06 0.30
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 6.831e-06 0.32
AROA_ECOLI aroA 3-phosphoshikimate 1-carboxyvinyltransferase 7.884e-06 0.31
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 9.916e-06 0.35

Resorcinol_monoacetate

DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 2.239e-51 0.38
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 1.423e-49 0.38
A6H249_FLAPJ pop Prolyl oligopeptidase family protein 5.512e-41 0.33
CFAD_RAT Cfd Complement factor D 5.512e-41 0.33
PA2A1_NAJMO Acidic phospholipase A2 CM-I 2.905e-40 0.32
KYNU_RAT Kynu Kynureninase 4.474e-39 0.31
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 3.875e-36 0.29
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 1.613e-33 0.38
MCR_RAT Nr3c2 Mineralocorticoid receptor 9.646e-24 0.32
BLAB_SERMA Metallo-beta-lactamase type 2 6.377e-23 0.28
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 5.145e-22 0.41
Q6RY99_RAT Tetraspanin 5.812e-22 0.31
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 1.778e-21 0.34
TLR1_MOUSE Tlr1 Toll-like receptor 1 3.219e-20 0.39
TLR2_MOUSE Tlr2 Toll-like receptor 2 3.219e-20 0.39
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 5.654e-19 0.36
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.375e-18 0.29
IMPA1_BOVIN IMPA1 Inositol monophosphatase 1 1.112e-17 0.32
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.966e-17 0.36
O96394_LEIAM Arginase 2.315e-17 0.31
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 4.583e-17 0.33
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.11e-16 0.36
G3HDX1_CRIGR Alpha-1B adrenergic receptor 3.331e-16 0.31
MYG_HUMAN MB Myoglobin 5.551e-16 0.30
Q2PCB5_DICLA ca Carbonic anhydrase 5.551e-16 0.44
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 3.997e-15 0.39
ACEA_CANAX ICL1 Isocitrate lyase 4.441e-15 0.29
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.221e-14 0.40
KYNU_HUMAN KYNU Kynureninase 3.697e-14 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 4.685e-14 0.42
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.862e-13 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 3.325e-13 0.34
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.417e-12 0.34
ANDR_MOUSE Ar Androgen receptor 3.743e-12 0.33
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.185e-12 0.36
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 9.09e-12 0.44
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.659e-11 0.31
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 2.335e-11 0.33
TTHY_HUMAN TTR Transthyretin 7.163e-11 0.32
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 8.581e-11 0.29
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 1.482e-10 0.44
ACRO_HUMAN ACR Acrosin 2.685e-10 0.32
AOX_TRYBB AOX Alternative oxidase, mitochondrial 1.863e-09 0.30
SPRE_HUMAN SPR Sepiapterin reductase 1.89e-09 0.36
ACES_HUMAN ACHE Acetylcholinesterase 2.884e-09 0.59
CAH6_HUMAN CA6 Carbonic anhydrase 6 3.38e-09 0.42
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 1.083e-08 0.31
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.264e-08 0.30
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 2.26e-08 0.44
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.386e-08 0.29
DHB14_HUMAN HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 4.085e-08 0.29
Q9BEG3_BOVIN 5-lipoxygenase 4.172e-08 0.36
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 4.868e-08 0.32
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 6.134e-08 0.51
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 6.634e-08 0.58
EST1_RABIT Liver carboxylesterase 1 6.959e-08 0.39
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 8.714e-08 0.41
LUCI_PHOPY Luciferin 4-monooxygenase 1.058e-07 0.38
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 1.199e-07 0.28
CHLE_HUMAN BCHE Cholinesterase 1.557e-07 0.44
STS_HUMAN STS Steryl-sulfatase 2.133e-07 0.40
CP1B1_HUMAN CYP1B1 Cytochrome P450 1B1 2.156e-07 0.37
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 3.003e-07 0.40
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.42e-07 0.30
CP1A1_HUMAN CYP1A1 Cytochrome P450 1A1 4.183e-07 0.33
ACES_MOUSE Ache Acetylcholinesterase 4.327e-07 0.40
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.686e-07 0.30
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 8.929e-07 0.40
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 9.643e-07 0.33
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.841e-06 0.44
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.845e-06 0.30
ELNE_HUMAN ELANE Neutrophil elastase 2.119e-06 0.38
MMP1_HUMAN MMP1 Interstitial collagenase 2.44e-06 0.41
O49150_SOLTU Lipoxygenase 2.481e-06 0.31
Q25270_LEIDO beta-tubulin Beta-tubulin 2.849e-06 0.29
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 2.925e-06 0.41
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.231e-06 0.36
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 3.477e-06 0.28
O40947_HHV8 ORF 73 4.462e-06 0.37
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.616e-06 0.32
PA21B_PIG PLA2G1B Phospholipase A2, major isoenzyme 8.306e-06 0.37
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 9.176e-06 0.37
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 9.492e-06 0.33

Vericiguat

P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 3.766e-49 0.35
BUB1_HUMAN BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 8.394e-35 0.34
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1.428e-27 0.35
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 7.25e-27 0.35
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 2.527e-20 0.31
KPYM_HUMAN PKM Pyruvate kinase PKM 1.11e-16 0.35
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2.868e-13 0.34
OGA_RAT Oga Protein O-GlcNAcase 4.673e-13 0.28
AGLU_SCHPO agl1 Alpha-glucosidase 5.641e-13 0.28
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 1.899e-12 0.34
Q9BJF5_TOXGO CDPK1 Calmodulin-domain protein kinase 1 4.602e-11 0.31
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 8.174e-11 0.34
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 2.56e-10 0.31
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 5.575e-10 0.29
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.854e-08 0.30
AA1R_BOVIN ADORA1 Adenosine receptor A1 6.606e-08 0.33
AA1R_HUMAN ADORA1 Adenosine receptor A1 2.286e-07 0.36
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.293e-06 0.36
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 2.992e-06 0.29

Pralsetinib

RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 1.123e-46 0.32
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 4.873e-27 0.34
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.565e-14 0.30
STA5B_HUMAN STAT5B Signal transducer and activator of transcription 5B 1.37e-12 0.29
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 1.065e-07 0.30
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 7.834e-07 0.29
AURKA_HUMAN AURKA Aurora kinase A 5.323e-06 0.34

Calcium_undecylenate

A3QR02_CHISP est1 Carboxylic ester hydrolase 2.861e-46 0.29
TRPV2_RAT Trpv2 Transient receptor potential cation channel subfamily V member 2 5.017e-19 0.32
EST1_RABIT Liver carboxylesterase 1 3.472e-10 0.31
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 6.452e-10 0.32
CQSS_VIBCH cqsS CAI-1 autoinducer sensor kinase/phosphatase CqsS 7.518e-07 0.29
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.198e-06 0.30

Serdexmethylphenidate

LMCPB_LEIME LMCPB Cysteine proteinase B 4.434e-45 0.30
IL2RA_HUMAN IL2RA Interleukin-2 receptor subunit alpha 2.325e-39 0.31
CBX5_HUMAN CBX5 Chromobox protein homolog 5 8.796e-36 0.28
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 7.18e-22 0.32
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 5.419e-21 0.30
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 6.024e-20 0.46
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 8.45e-19 0.32
LGMN_HUMAN LGMN Legumain 3.775e-14 0.31
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 8.737e-14 0.28
ACE_HUMAN ACE Angiotensin-converting enzyme 1.232e-13 0.34
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.666e-12 0.30
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.308e-11 0.35
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 2.78e-10 0.35
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 3.133e-10 0.30
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 7.541e-10 0.29
MLX_HUMAN MLX Max-like protein X 1.045e-09 0.28
PPCE_BOVIN PREP Prolyl endopeptidase 1.37e-09 0.30
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 3.658e-09 0.30
IL2RA_MOUSE Il2ra Interleukin-2 receptor subunit alpha 8.478e-09 0.31
PPCE_PIG PREP Prolyl endopeptidase 1.085e-08 0.30
Q8WMX0_BOVIN Muscarinic receptor M1 1.136e-08 0.30
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.665e-08 0.28
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.424e-07 0.30
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.767e-07 0.31
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 3.677e-07 0.30
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 5.325e-07 0.28
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.213e-06 0.30
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 1.272e-06 0.30
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.539e-06 0.30
PPCE_HUMAN PREP Prolyl endopeptidase 1.718e-06 0.34
KLK5_HUMAN KLK5 Kallikrein-5 2.185e-06 0.29

Iptacopan

SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 7.218e-44 0.32
Q53I59_TRYCR PDEC Phosphodiesterase 1.11e-16 0.34
CFAB_HUMAN CFB Complement factor B 2.331e-14 0.29
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.615e-11 0.31
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 9.501e-08 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.964e-06 0.29

Belzutifan

S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 1.875e-40 0.38
EPAS1_HUMAN EPAS1 Endothelial PAS domain-containing protein 1 1.393e-29 0.69
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 1.898e-06 0.35
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 8.279e-06 0.28

ATH434

AMPL_YEAST APE1 Vacuolar aminopeptidase 1 2.281e-40 0.32
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 9.636e-06 0.29

Sepiapterin

PH4H_HUMAN PAH Phenylalanine-4-hydroxylase 7.545e-40 0.32
Q81VW8_BACAN folP Dihydropteroate synthase 1.305e-13 0.37

Mobocertinib

DUS2L_HUMAN DUS2 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like 1.356e-39 0.31
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.519e-35 0.73
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.604e-30 0.34
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.965e-26 0.36
FGFR4_HUMAN FGFR4 Fibroblast growth factor receptor 4 3.726e-25 0.37
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 7.886e-25 0.35
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 6.684e-23 0.32
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 1.774e-22 0.73
ERBB3_HUMAN ERBB3 Receptor tyrosine-protein kinase erbB-3 5.856e-19 0.73
MK01_RAT Mapk1 Mitogen-activated protein kinase 1 1.11e-16 0.32
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 2.998e-15 0.35
INSR_HUMAN INSR Insulin receptor 7.105e-15 0.73
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 3.431e-14 0.32
FAK1_HUMAN PTK2 Focal adhesion kinase 1 2.742e-12 0.33
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 1.358e-11 0.37
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 2.098e-11 0.31
TTK_HUMAN TTK Dual specificity protein kinase TTK 7.286e-10 0.38
DCLK1_HUMAN DCLK1 Serine/threonine-protein kinase DCLK1 1.61e-09 0.30
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 1.795e-09 0.30
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 2.875e-09 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 9.788e-09 0.32
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 1.219e-07 0.30
TSSK2_HUMAN TSSK2 Testis-specific serine/threonine-protein kinase 2 1.53e-07 0.30
DCLK2_HUMAN DCLK2 Serine/threonine-protein kinase DCLK2 3.137e-07 0.28
BTK_HUMAN BTK Tyrosine-protein kinase BTK 6.384e-07 0.38
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 7.594e-07 0.35
TXK_HUMAN TXK Tyrosine-protein kinase TXK 1.147e-06 0.38
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.54e-06 0.38

Zinc_phenolsulfonate

SSDH_HUMAN ALDH5A1 Succinate-semialdehyde dehydrogenase, mitochondrial 3.543e-39 0.31
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 5.86e-39 0.38
GABT_HUMAN ABAT 4-aminobutyrate aminotransferase, mitochondrial 3.332e-25 0.31
H9TVJ1_CHISP TyR1 2.847e-23 0.29
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 8.099e-23 0.57
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 3.57e-22 0.32
CAH3_HUMAN CA3 Carbonic anhydrase 3 4.509e-21 0.36
CAH2_BOVIN CA2 Carbonic anhydrase 2 5.388e-20 0.30
C0IX24_STYPI CA2 Carbonic anhydrase 2.019e-19 0.30
B2V8E3_SULSY Carbonate dehydratase 1.095e-18 0.30
B5SU02_STYPI CA Alpha carbonic anhydrase 1.095e-18 0.30
Q31FD6_HYDCU Carbonic anhydrase, alpha family 1.095e-18 0.30
CAH15_MOUSE Ca15 Carbonic anhydrase 15 1.113e-18 0.36
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.117e-18 0.45
A6YCJ1_9METZ Astrosclerin-3 1.04e-17 0.30
MYG_HUMAN MB Myoglobin 1.11e-16 0.32
CYNT_HELPY cynT Carbonic anhydrase 4.441e-16 0.30
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 7.438e-15 0.28
CAN_CANAL NCE103 Carbonic anhydrase 7.183e-14 0.32
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.565e-13 0.35
Q2PCB5_DICLA ca Carbonic anhydrase 2.98e-13 0.36
Q6FTL6_CANGA NCE103 Carbonic anhydrase 8.811e-11 0.30
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 4.243e-10 0.36
CAH6_HUMAN CA6 Carbonic anhydrase 6 8.946e-10 0.36
MTSI_SPISQ sssIM CPG DNA methylase 2.635e-09 0.29
ESR1_HUMAN ESR1 Estrogen receptor 3.931e-09 0.43
Q5TU56_ANOGA 1272966 Carbonic anhydrase 4.999e-09 0.30
AK1A1_RAT Akr1a1 Aldo-keto reductase family 1 member A1 1.322e-08 0.29
CAN_YEAST NCE103 Carbonic anhydrase 1.88e-08 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 9.412e-08 0.30
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.366e-07 0.36
CAH7_HUMAN CA7 Carbonic anhydrase 7 2.032e-07 0.45
O49150_SOLTU Lipoxygenase 3.121e-07 0.36
CAH2_HUMAN CA2 Carbonic anhydrase 2 3.576e-07 0.57
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 3.958e-07 0.33
5NTD_HUMAN NT5E 5'-nucleotidase 5.944e-07 0.33
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.617e-06 0.36
CAH_METTE Carbonic anhydrase 4.586e-06 0.30
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 8.457e-06 0.33

Potassium_aspartate

AAA1_RAT Slc7a10 Asc-type amino acid transporter 1 1.917e-37 0.30
VGLU3_RAT Slc17a8 Vesicular glutamate transporter 3 2.576e-18 0.29

Adagrasib

ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.408e-36 0.30
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 3.032e-08 0.29

Mebrofenin

CAH4_BOVIN CA4 Carbonic anhydrase 4 3.91e-33 0.44
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.665e-17 0.39
CAH1_HUMAN CA1 Carbonic anhydrase 1 7.273e-13 0.44
CAH2_HUMAN CA2 Carbonic anhydrase 2 5.248e-12 0.44
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 4.596e-06 0.29

Nirmatrelvir

A3EZI9_9HEPC NS3 Genome polyprotein 2.422e-31 0.45
Q91RS4_9HEPC NS3 protease 2.834e-12 0.33
CATF_HUMAN CTSF Cathepsin F 1.675e-06 0.44

Odevixibat

NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.445e-28 0.32
NTCP2_RAT Slc10a2 Ileal sodium/bile acid cotransporter 1.797e-13 0.29
NTCP2_MOUSE Slc10a2 Ileal sodium/bile acid cotransporter 4.853e-12 0.29
CPNS1_HUMAN CAPNS1 Calpain small subunit 1 2.696e-06 0.29

Repotrectinib

NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 1.91e-26 0.33
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 7.627e-14 0.35
PDE9A_HUMAN PDE9A High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 1.701e-06 0.29
PDE1C_HUMAN PDE1C Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 3.091e-06 0.29

Remibrutinib

BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.919e-24 0.44
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 8.422e-18 0.36
LIMK1_RAT Limk1 LIM domain kinase 1 1.11e-16 0.30

Ensifentrine

MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 1.998e-22 0.68
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 3.571e-11 0.31
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 2.282e-08 0.30
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 1.894e-07 0.35
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.151e-07 0.35
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 6.259e-07 0.38
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 1.054e-06 0.30

Sodium_camphorsulfonate

OXYR_RAT Oxtr Oxytocin receptor 6.792e-22 0.47
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 7.476e-21 0.55
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 2.011e-18 0.44
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.027e-17 0.55
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 4.425e-11 0.48

Olutasidenib

Q91ZY3_CAVPO HRH4 Histamine H4 receptor 5.429e-20 0.32
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 1.042e-17 0.31
BCAT2_HUMAN BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial 2.22e-15 0.29
HRH4_MOUSE Hrh4 Histamine H4 receptor 7.194e-12 0.32
PRGR_HUMAN PGR Progesterone receptor 6.991e-10 0.37
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.054e-06 0.29
HRH4_RAT Hrh4 Histamine H4 receptor 8.126e-06 0.32

Brilliant_blue_G

P2RX7_MOUSE P2rx7 P2X purinoceptor 7 4.408e-14 0.89
P2RY1_MELGA P2RY1 P2Y purinoceptor 1 1.012e-06 0.89

Thenyldiamine

Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.739e-13 0.34
ANM1_RAT Prmt1 Protein arginine N-methyltransferase 1 1.23e-11 0.28
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 5.206e-11 0.34
CALM_BOVIN CALM Calmodulin 7.306e-11 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 1.168e-10 0.61
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 6.319e-10 0.31
CALM1_HUMAN CALM1 Calmodulin-1 2.929e-08 0.29
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.68e-07 0.28
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 5.584e-07 0.39
HRH1_HUMAN HRH1 Histamine H1 receptor 7.207e-07 0.70

Magnesium_malate

LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 7.443e-13 0.29

Sotorasib

SMO_HUMAN SMO Smoothened homolog 1.331e-09 0.33

Selpercatinib

P2RX2_HUMAN P2RX2 P2X purinoceptor 2 4.908e-08 0.32

Sulopenem_etzadroxil

LEP_ECOLI lepB Signal peptidase I 5.941e-08 0.31