Results of Job: search_85f98963-3380-4601-a886-b08a5b5abd6e

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 2.119e-184 0.60
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 3.168e-100 0.49
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 8.415e-99 0.43
CEPT1_HUMAN CEPT1 Choline/ethanolaminephosphotransferase 1 2.524e-95 0.35
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 1.421e-81 0.36
C3SLB7_ECOLX glmU Bifunctional protein GlmU 8.942e-72 0.40
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.862e-68 0.40
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 1.209e-65 0.35
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.98e-62 0.40
Q8IL11_PLAF7 M17 leucyl aminopeptidase 1.833e-59 0.45
ETHR_MYCS2 ethR HTH-type transcriptional regulator EthR 2.412e-58 0.36
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 4.02e-54 0.39
ERBB2_RAT Erbb2 Receptor tyrosine-protein kinase erbB-2 7.653e-52 0.33
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.891e-49 0.44
MET_HUMAN MET Hepatocyte growth factor receptor 1.384e-45 0.41
SHH_MOUSE Shh Sonic hedgehog protein 1.679e-43 0.37
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 9.984e-43 0.47
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.251e-40 0.38
PRIO_HUMAN PRNP Major prion protein 9.344e-37 0.37
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.229e-36 0.40
O31272_9GAMM imiS Beta-lactamase 9.344e-36 0.31
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 1.144e-34 0.40
PDE2A_BOVIN PDE2A cGMP-dependent 3',5'-cyclic phosphodiesterase 2.96e-32 0.34
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 9.749e-32 0.33
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.661e-30 0.32
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 4.08e-30 0.41
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 2.014e-29 0.37
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 2.039e-28 0.38
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 3.139e-28 0.37
KC1D_RAT Csnk1d Casein kinase I isoform delta 6.142e-28 0.45
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 9.393e-28 0.34
PI4KA_HUMAN PI4KA Phosphatidylinositol 4-kinase alpha 1.49e-26 0.36
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 7.455e-26 0.30
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 7.472e-25 0.49
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.132e-24 0.49
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 2.098e-24 0.34
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.676e-24 0.36
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.089e-23 0.45
S27A1_MOUSE Slc27a1 Long-chain fatty acid transport protein 1 1.765e-23 0.35
TLR4_HUMAN TLR4 Toll-like receptor 4 2.646e-23 0.38
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.36e-23 0.45
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 7.318e-23 0.28
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 7.686e-23 0.46
TSHR_HUMAN TSHR Thyrotropin receptor 3.21e-22 0.37
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.331e-22 0.38
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 1.981e-21 0.33
AUKBA_XENLA aurkb-a Aurora kinase B-A 2.329e-21 0.34
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 6.221e-21 0.31
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 6.652e-21 0.33
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 2.525e-20 0.49
CETP_HUMAN CETP Cholesteryl ester transfer protein 3.179e-20 0.37
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.136e-20 0.39
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 5.482e-20 0.30
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 8.689e-20 0.39
Q38C41_TRYB2 Phosphotransferase 1.276e-19 0.37
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 1.825e-19 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.635e-19 0.31
ATM_HUMAN ATM Serine-protein kinase ATM 4.362e-19 0.30
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 4.7e-19 0.47
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 8.741e-19 0.35
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 1.431e-18 0.35
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 1.891e-18 0.33
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 3.886e-18 0.29
LIPL_BOVIN LPL Lipoprotein lipase 7.773e-18 0.28
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 2.215e-17 0.37
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 1.11e-16 0.42
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.11e-16 0.29
PANK1_HUMAN PANK1 Pantothenate kinase 1 5.551e-16 0.30
ACES_ELEEL ache Acetylcholinesterase 8.882e-16 0.36
PTN12_HUMAN PTPN12 Tyrosine-protein phosphatase non-receptor type 12 9.992e-16 0.34
PA21B_HUMAN PLA2G1B Phospholipase A2 1.776e-15 0.49
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 2.22e-15 0.38
AXIN2_HUMAN AXIN2 Axin-2 3.664e-15 0.29
FTSZ_STAAU ftsZ Cell division protein FtsZ 7.105e-15 0.28
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 7.772e-15 0.33
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 1.155e-14 0.34
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.388e-14 0.36
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.61e-14 0.37
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 1.776e-14 0.34
PPGB_HUMAN CTSA Lysosomal protective protein 2.198e-14 0.31
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 4.885e-14 0.29
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 4.929e-14 0.34
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 7.405e-14 0.43
Q9NBA7_PLAFA Cysteine protease falcipain-3 9.026e-14 0.38
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.266e-13 0.37
RECA_MYCTU recA Protein RecA 3.328e-13 0.42
MET_MOUSE Met Hepatocyte growth factor receptor 3.373e-13 0.29
HPSE_HUMAN HPSE Heparanase 5.537e-13 0.32
Q93EK7_NEIME lgtC LgtC 5.641e-13 0.28
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 6.128e-13 0.32
HGF_HUMAN HGF Hepatocyte growth factor 6.325e-13 0.28
CASB_RAT Csn2 Beta-casein 6.588e-13 0.28
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 8.831e-13 0.38
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.936e-12 0.32
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 2.088e-12 0.35
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 2.427e-12 0.39
PRIO_SHEEP PRNP Major prion protein 2.629e-12 0.31
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 4.037e-12 0.37
XBP1_HUMAN XBP1 X-box-binding protein 1 4.59e-12 0.39
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 4.913e-12 0.46
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.237e-11 0.32
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 1.825e-11 0.33
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.915e-11 0.38
HSF1_MOUSE Hsf1 Heat shock factor protein 1 2.007e-11 0.43
AURKA_HUMAN AURKA Aurora kinase A 2.182e-11 0.39
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 2.584e-11 0.36
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.972e-11 0.33
ABC3G_HUMAN APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G 3.824e-11 0.38
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 4.393e-11 0.30
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 4.937e-11 0.30
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.964e-11 0.33
STF1_HUMAN NR5A1 Steroidogenic factor 1 6.642e-11 0.34
GYRA_STAAU gyrA DNA gyrase subunit A 8.172e-11 0.32
MEP50_HUMAN WDR77 Methylosome protein 50 8.833e-11 0.37
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 9.067e-11 0.38
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.139e-10 0.37
RON_HUMAN MST1R Macrophage-stimulating protein receptor 1.2e-10 0.38
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 1.675e-10 0.28
S100B_HUMAN S100B Protein S100-B 2.015e-10 0.30
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 2.139e-10 0.32
DNAB_MYCTU dnaB Replicative DNA helicase 2.221e-10 0.42
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 2.453e-10 0.35
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.58e-10 0.38
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 2.875e-10 0.42
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 3.47e-10 0.38
PTN22_HUMAN PTPN22 Tyrosine-protein phosphatase non-receptor type 22 3.928e-10 0.34
CHLE_HORSE BCHE Cholinesterase 4.528e-10 0.34
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 5.005e-10 0.35
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 7.172e-10 0.44
TERT_HUMAN TERT Telomerase reverse transcriptase 7.583e-10 0.31
E2AK3_HUMAN EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 7.961e-10 0.33
S12A5_HUMAN SLC12A5 Solute carrier family 12 member 5 8.388e-10 0.30
KHK_HUMAN KHK Ketohexokinase 9.022e-10 0.33
PDE10_HUMAN PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 9.086e-10 0.39
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 9.541e-10 0.39
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 1.892e-09 0.30
MDH_THETH mdh Malate dehydrogenase 2.039e-09 0.29
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.088e-09 0.33
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 2.353e-09 0.36
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 3.511e-09 0.33
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 4.719e-09 0.35
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 6.635e-09 0.33
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 7.03e-09 0.36
AURKB_HUMAN AURKB Aurora kinase B 8.251e-09 0.38
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.086e-08 0.36
DUS6_RAT Dusp6 Dual specificity protein phosphatase 6 1.231e-08 0.34
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.336e-08 0.38
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.666e-08 0.31
TNFA_HUMAN TNF Tumor necrosis factor 1.948e-08 0.35
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 2.332e-08 0.34
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.41e-08 0.39
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.592e-08 0.36
CCKAR_RAT Cckar Cholecystokinin receptor type A 2.601e-08 0.38
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 3.063e-08 0.35
ITA3_HUMAN ITGA3 Integrin alpha-3 4.354e-08 0.29
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 4.441e-08 0.33
SENP7_HUMAN SENP7 Sentrin-specific protease 7 4.562e-08 0.33
KLK6_HUMAN KLK6 Kallikrein-6 5.431e-08 0.28
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 5.732e-08 0.38
REV1_HUMAN REV1 DNA repair protein REV1 6.729e-08 0.29
BGLR_HUMAN GUSB Beta-glucuronidase 7.536e-08 0.31
PDE11_HUMAN PDE11A Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 7.642e-08 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 7.855e-08 0.38
GPR55_HUMAN GPR55 G-protein coupled receptor 55 8.431e-08 0.44
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 8.52e-08 0.38
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 9.64e-08 0.30
GALR3_HUMAN GALR3 Galanin receptor type 3 1.043e-07 0.33
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.106e-07 0.29
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 1.338e-07 0.33
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 1.93e-07 0.39
NRAM2_HUMAN SLC11A2 Natural resistance-associated macrophage protein 2 1.949e-07 0.30
STRP_STRP1 ska Streptokinase A 2.118e-07 0.42
WNT3A_MOUSE Wnt3a Protein Wnt-3a 2.148e-07 0.29
O97467_PLAFA ht1 Hexose transporter 1 2.293e-07 0.38
O61059_LEIME LmGT2 Glucose transporter 2.582e-07 0.38
LCK_HUMAN LCK Tyrosine-protein kinase Lck 3.118e-07 0.38
BRPF1_HUMAN BRPF1 Peregrin 3.567e-07 0.32
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.674e-07 0.43
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.719e-07 0.37
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 3.733e-07 0.38
GP142_MOUSE Gpr142 Probable G-protein coupled receptor 142 4.177e-07 0.29
IDE_HUMAN IDE Insulin-degrading enzyme 4.293e-07 0.34
KLF5_HUMAN KLF5 Krueppel-like factor 5 4.494e-07 0.30
COT2_HUMAN NR2F2 COUP transcription factor 2 4.579e-07 0.33
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 4.627e-07 0.36
HDAC8_HUMAN HDAC8 Histone deacetylase 8 5.53e-07 0.36
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.327e-07 0.38
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 7.618e-07 0.35
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 9.396e-07 0.29
GYRB_STAAU gyrB DNA gyrase subunit B 9.91e-07 0.32
ACRO_HUMAN ACR Acrosin 1.09e-06 0.29
KLK7_HUMAN KLK7 Kallikrein-7 1.23e-06 0.39
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.276e-06 0.36
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 1.331e-06 0.34
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 1.331e-06 0.31
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.603e-06 0.31
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 1.655e-06 0.34
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.658e-06 0.30
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.732e-06 0.34
CHLE_HUMAN BCHE Cholinesterase 1.838e-06 0.33
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.841e-06 0.28
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 2.2e-06 0.33
STAT1_HUMAN STAT1 Signal transducer and activator of transcription 1-alpha/beta 2.809e-06 0.36
CBPB1_HUMAN CPB1 Carboxypeptidase B 2.898e-06 0.29
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 3.269e-06 0.51
CETP_RABIT CETP Cholesteryl ester transfer protein 3.42e-06 0.29
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 3.457e-06 0.38
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 3.699e-06 0.32
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 3.71e-06 0.29
JUN_HUMAN JUN Transcription factor AP-1 3.775e-06 0.34
PTN5_HUMAN PTPN5 Tyrosine-protein phosphatase non-receptor type 5 4.112e-06 0.38
PANC_MYCTU panC Pantothenate synthetase 4.159e-06 0.29
NCOA3_HUMAN NCOA3 Nuclear receptor coactivator 3 4.407e-06 0.43
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 4.596e-06 0.29
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 4.596e-06 0.29
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 5.19e-06 0.38
DPOL_VACCW POL DNA polymerase 6.166e-06 0.29
DYR_HUMAN DHFR Dihydrofolate reductase 6.201e-06 0.36
ACOD1_RAT Scd1 Acyl-CoA desaturase 1 6.496e-06 0.33
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 7.139e-06 0.43
TRYP_PIG Trypsin 7.336e-06 0.33
CCR6_HUMAN CCR6 C-C chemokine receptor type 6 7.652e-06 0.28
MITF_HUMAN MITF Microphthalmia-associated transcription factor 7.935e-06 0.31
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 8.402e-06 0.31
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 8.742e-06 0.37
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 9.199e-06 0.36