Results of Job: search_90e505c2-d827-4d33-8ad2-a2efb8b29b12

Query Target Key Target Name Description P-Value MaxTC

compound_1

TYSY_MOUSE Tyms Thymidylate synthase 9.17e-303 0.56
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 8.649e-199 0.53
TYSY_HUMAN TYMS Thymidylate synthase 5.475e-148 0.55
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 4.825e-130 0.53
FOLR1_HUMAN FOLR1 Folate receptor alpha 3.703e-129 0.43
DYR_ENTFC folA Dihydrofolate reductase 7.084e-126 0.49
PCFT_HUMAN SLC46A1 Proton-coupled folate transporter 5.032e-120 0.43
DYR_MOUSE Dhfr Dihydrofolate reductase 2.395e-118 0.46
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 4.189e-116 0.44
FOLR2_HUMAN FOLR2 Folate receptor beta 2.064e-106 0.43
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 1.898e-100 0.53
S19A1_HUMAN SLC19A1 Reduced folate transporter 7.85e-84 0.41
DYR_LACCA folA Dihydrofolate reductase 3.306e-83 0.46
TYSY_RAT Tyms Thymidylate synthase 4.524e-75 0.46
Q9I056_PSEAE cpg2 Carboxypeptidase G2 1.691e-74 0.42
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 4.024e-73 0.37
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 4.601e-72 0.43
DYR_HUMAN DHFR Dihydrofolate reductase 5.956e-72 0.54
E2QDN0_ECOLX thyA Thymidylate synthase 2.606e-70 0.46
ENPP1_HUMAN ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 8.083e-69 0.42
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 2.328e-59 0.34
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.314e-58 0.34
TYSY_LACCA thyA Thymidylate synthase 3.345e-57 0.47
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.81e-53 0.32
FOLC_ECOLI folC Dihydrofolate synthase/folylpolyglutamate synthase 1.559e-52 0.42
ITA3_HUMAN ITGA3 Integrin alpha-3 1.892e-51 0.38
Q8IL11_PLAF7 M17 leucyl aminopeptidase 5.568e-49 0.44
MTDC_HUMAN MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 1.697e-47 0.38
ATS1_HUMAN ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1 7.376e-45 0.30
C3SLN3_ECOLX gyrB DNA gyrase subunit B 1.19e-39 0.30
METH_HUMAN MTR Methionine synthase 1.098e-38 0.32
BLAN1_KLEPN blaNDM-1 Metallo-beta-lactamase type 2 2.959e-38 0.35
C3SWJ7_ECOLX thyA Thymidylate synthase 5.315e-33 0.46
DYR_RAT Dhfr Dihydrofolate reductase 6.733e-33 0.53
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 1.518e-31 0.35
D2K2A8_9HEPC NS4A Non-structural protein 4A 1.755e-30 0.40
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 3.251e-29 0.41
FOLH1_RAT Folh1 Glutamate carboxypeptidase 2 3.398e-29 0.38
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.5e-28 0.34
HMGB1_HUMAN HMGB1 High mobility group protein B1 5.245e-27 0.33
A3EZI9_9HEPC NS3 Genome polyprotein 6.418e-25 0.40
GYRA_STAAU gyrA DNA gyrase subunit A 6.025e-24 0.40
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 9.126e-24 0.33
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 9.411e-24 0.37
PUR9_HUMAN ATIC Bifunctional purine biosynthesis protein PURH 1.112e-23 0.51
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 2.063e-23 0.29
ENL_HUMAN MLLT1 Protein ENL 2.117e-23 0.29
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 3.122e-23 0.34
GGH_HUMAN GGH Gamma-glutamyl hydrolase 4.035e-23 0.28
DYR_MYCTU folA Dihydrofolate reductase 3.693e-22 0.33
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 4.805e-22 0.31
NALD2_HUMAN NAALAD2 N-acetylated-alpha-linked acidic dipeptidase 2 1.5e-21 0.30
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 2.342e-21 0.43
EF1A1_HUMAN EEF1A1 Elongation factor 1-alpha 1 4.321e-21 0.34
EF1A2_HUMAN EEF1A2 Elongation factor 1-alpha 2 4.321e-21 0.34
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 6.261e-21 0.36
PRIO_HUMAN PRNP Major prion protein 7.418e-21 0.38
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.472e-20 0.31
ITA2_HUMAN ITGA2 Integrin alpha-2 2.561e-20 0.38
X5EH84_STAAU folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 2.511e-19 0.37
GLUC_HUMAN GCG Glucagon 2.786e-19 0.32
WNK3_HUMAN WNK3 Serine/threonine-protein kinase WNK3 1.126e-18 0.30
AUKBA_XENLA aurkb-a Aurora kinase B-A 1.187e-18 0.30
Q9ZTP8_MAIZE hd1b Histone deacetylase 8.035e-18 0.31
MMP2_MOUSE Mmp2 72 kDa type IV collagenase 9.056e-18 0.28
MMP9_MOUSE Mmp9 Matrix metalloproteinase-9 9.056e-18 0.28
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 1.671e-17 0.46
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 2.53e-17 0.34
ANPRC_HUMAN NPR3 Atrial natriuretic peptide receptor 3 1.11e-16 0.29
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 1.11e-16 0.29
TNKS1_HUMAN TNKS Poly [ADP-ribose] polymerase tankyrase-1 2.22e-16 0.39
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 5.551e-16 0.58
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.332e-15 0.31
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 1.665e-15 0.29
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.442e-15 0.38
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 4.441e-15 0.29
CTNB1_HUMAN CTNNB1 Catenin beta-1 4.552e-15 0.38
GYRB_STAAU gyrB DNA gyrase subunit B 6.55e-15 0.40
GLR_HUMAN GCGR Glucagon receptor 7.105e-15 0.35
CATL1_HUMAN CTSL Cathepsin L1 7.438e-15 0.35
GIPR_HUMAN GIPR Gastric inhibitory polypeptide receptor 8.66e-15 0.34
GRB7_HUMAN GRB7 Growth factor receptor-bound protein 7 1.044e-14 0.32
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 1.71e-14 0.29
ANO2_HUMAN ANO2 Anoctamin-2 4.508e-14 0.38
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 6.739e-14 0.37
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.294e-14 0.40
ITB3_HUMAN ITGB3 Integrin beta-3 1.038e-13 0.41
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 1.187e-13 0.31
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 3.156e-13 0.33
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 4.864e-13 0.37
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 8.203e-13 0.33
HDAC2_HUMAN HDAC2 Histone deacetylase 2 8.408e-13 0.34
MEP50_HUMAN WDR77 Methylosome protein 50 8.731e-13 0.45
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.179e-12 0.45
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.259e-12 0.31
PARP3_HUMAN PARP3 Protein mono-ADP-ribosyltransferase PARP3 1.4e-12 0.32
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.847e-12 0.34
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.918e-12 0.31
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 4.091e-12 0.31
DHPS_ECOLI folP Dihydropteroate synthase 4.996e-12 0.37
MMP13_HUMAN MMP13 Collagenase 3 6.945e-12 0.39
CATS_HUMAN CTSS Cathepsin S 8.063e-12 0.35
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 9.926e-12 0.31
DYR_CHICK DHFR Dihydrofolate reductase 1.04e-11 0.36
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.476e-11 0.34
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.692e-11 0.36
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 2.459e-11 0.34
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.273e-11 0.42
PDE9A_HUMAN PDE9A High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 3.878e-11 0.39
F1SH20_PIG TRHDE Uncharacterized protein 4.196e-11 0.30
TNF11_MOUSE Tnfsf11 Tumor necrosis factor ligand superfamily member 11 5.386e-11 0.29
ENTK_HUMAN TMPRSS15 Enteropeptidase 5.438e-11 0.30
CCKAR_RAT Cckar Cholecystokinin receptor type A 5.862e-11 0.32
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 1.105e-10 0.29
HDAC8_HUMAN HDAC8 Histone deacetylase 8 1.277e-10 0.39
AURKA_HUMAN AURKA Aurora kinase A 1.499e-10 0.33
DYR_PNECA Dihydrofolate reductase 1.533e-10 0.38
AURKB_HUMAN AURKB Aurora kinase B 2.065e-10 0.34
TYSY_ECOLI thyA Thymidylate synthase 4.061e-10 0.46
NR2E3_HUMAN NR2E3 Photoreceptor-specific nuclear receptor 4.768e-10 0.34
MMP13_BOVIN MMP13 Collagenase 3 5.217e-10 0.30
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 6.176e-10 0.36
Q81R22_BACAN dfrA Dihydrofolate reductase 6.698e-10 0.36
Q38C41_TRYB2 Phosphotransferase 8.067e-10 0.31
Q6DMN0_TOXGO CPL Cathepsin L 8.577e-10 0.28
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 9.102e-10 0.34
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 1.179e-09 0.36
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 1.557e-09 0.32
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.969e-09 0.33
GLP1R_RAT Glp1r Glucagon-like peptide 1 receptor 3.598e-09 0.29
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 4.108e-09 0.31
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 4.199e-09 0.31
HPSE_HUMAN HPSE Heparanase 5.552e-09 0.33
ANPRA_HUMAN NPR1 Atrial natriuretic peptide receptor 1 5.625e-09 0.29
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 6.739e-09 0.48
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 6.842e-09 0.32
AA3R_HUMAN ADORA3 Adenosine receptor A3 8.143e-09 0.34
TNKS2_HUMAN TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 1.217e-08 0.39
PANK1_HUMAN PANK1 Pantothenate kinase 1 1.399e-08 0.30
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 1.433e-08 0.42
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 3.051e-08 0.31
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 3.435e-08 0.31
CATK_HUMAN CTSK Cathepsin K 3.586e-08 0.39
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 4.253e-08 0.36
DYR_BOVIN DHFR Dihydrofolate reductase 4.278e-08 0.33
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 4.5e-08 0.31
TRY1_HUMAN PRSS1 Trypsin-1 6.824e-08 0.33
FA7_HUMAN F7 Coagulation factor VII 7.121e-08 0.33
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 7.247e-08 0.35
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 1.031e-07 0.29
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.219e-07 0.29
ANDR_MOUSE Ar Androgen receptor 1.284e-07 0.32
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 1.3e-07 0.42
TPA_HUMAN PLAT Tissue-type plasminogen activator 1.802e-07 0.34
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.995e-07 0.29
PTN7_HUMAN PTPN7 Tyrosine-protein phosphatase non-receptor type 7 2.061e-07 0.36
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 2.1e-07 0.39
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 2.549e-07 0.33
ITB1_HUMAN ITGB1 Integrin beta-1 3.373e-07 0.34
O97467_PLAFA ht1 Hexose transporter 1 3.463e-07 0.33
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 3.738e-07 0.34
Q25615_ONCVO Chitinase 3.923e-07 0.29
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 4.905e-07 0.29
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 5.193e-07 0.30
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 5.578e-07 0.32
UR2R_HUMAN UTS2R Urotensin-2 receptor 5.584e-07 0.31
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 5.631e-07 0.48
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 5.815e-07 0.28
CSK21_HUMAN CSNK2A1 Casein kinase II subunit alpha 5.861e-07 0.34
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.944e-07 0.33
MMP12_HUMAN MMP12 Macrophage metalloelastase 6.834e-07 0.31
EGLN2_HUMAN EGLN2 Egl nine homolog 2 6.931e-07 0.30
HDAC5_HUMAN HDAC5 Histone deacetylase 5 6.934e-07 0.30
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 8.058e-07 0.29
HDAC7_HUMAN HDAC7 Histone deacetylase 7 8.191e-07 0.30
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 8.319e-07 0.31
FUCO_RAT Fuca1 Tissue alpha-L-fucosidase 8.621e-07 0.32
GYRB_MYCSM gyrB DNA gyrase subunit B 8.626e-07 0.33
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 8.817e-07 0.39
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 9.101e-07 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 9.101e-07 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 9.101e-07 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 9.101e-07 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 9.101e-07 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 9.101e-07 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 9.101e-07 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 9.101e-07 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 9.101e-07 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 9.101e-07 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 9.101e-07 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 9.101e-07 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 9.101e-07 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 9.101e-07 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 9.101e-07 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 9.101e-07 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 9.101e-07 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 9.101e-07 0.30
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 9.331e-07 0.29
HDAC6_HUMAN HDAC6 Histone deacetylase 6 1.27e-06 0.35
PRIO_SHEEP PRNP Major prion protein 1.358e-06 0.30
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.415e-06 0.29
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 1.585e-06 0.33
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 1.627e-06 0.38
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 1.628e-06 0.37
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.744e-06 0.34
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.991e-06 0.38
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.122e-06 0.38
MET_HUMAN MET Hepatocyte growth factor receptor 2.441e-06 0.33
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 2.889e-06 0.32
UROK_HUMAN PLAU Urokinase-type plasminogen activator 3.537e-06 0.34
MMP2_HUMAN MMP2 72 kDa type IV collagenase 3.568e-06 0.36
LYOX_HUMAN LOX Protein-lysine 6-oxidase 3.572e-06 0.30
PPGB_HUMAN CTSA Lysosomal protective protein 3.601e-06 0.29
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 4.112e-06 0.30
CAH2_HUMAN CA2 Carbonic anhydrase 2 4.299e-06 0.41
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 4.37e-06 0.32
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.596e-06 0.29
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 4.64e-06 0.29
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 4.809e-06 0.30
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 4.833e-06 0.36
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 4.893e-06 0.29
SIR5_HUMAN SIRT5 NAD-dependent protein deacylase sirtuin-5, mitochondrial 4.923e-06 0.33
ITA4_HUMAN ITGA4 Integrin alpha-4 4.983e-06 0.34
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 5.137e-06 0.33
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 6.024e-06 0.31
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 6.36e-06 0.29
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 6.464e-06 0.31
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.112e-06 0.29
LUCI_AQULA Luciferin 4-monooxygenase 8.279e-06 0.28
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 8.734e-06 0.34
SGK2_HUMAN SGK2 Serine/threonine-protein kinase Sgk2 9.051e-06 0.34
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 9.78e-06 0.34