Results of Job: search_92b7bffe-f539-4b73-a956-c16847e5fc06

Query Target Key Target Name Description P-Value MaxTC

compound_1

ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 6.706e-224 0.48
INSR_HUMAN INSR Insulin receptor 2.705e-71 0.38
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.452e-61 0.31
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 4.821e-60 0.39
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.133e-59 0.39
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 2.527e-57 0.38
KDM1B_HUMAN KDM1B Lysine-specific histone demethylase 1B 1.688e-53 0.30
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 4.824e-46 0.42
DRD1_BOVIN DRD1 D(1A) dopamine receptor 1.224e-45 0.35
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 4.479e-45 0.36
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 2.248e-43 0.33
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 2.688e-43 0.38
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.238e-42 0.42
OGA_RAT Oga Protein O-GlcNAcase 1.539e-42 0.34
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 3.595e-42 0.38
CTNB1_HUMAN CTNNB1 Catenin beta-1 5.316e-40 0.33
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 2.547e-37 0.38
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 2.531e-36 0.56
GYRB_STRPN gyrB DNA gyrase subunit B 9.248e-36 0.31
Q7X1P7_STREE parE DNA topoisomerase (ATP-hydrolyzing) 9.248e-36 0.31
PARE_ECOLI parE DNA topoisomerase 4 subunit B 1.139e-35 0.30
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 1.263e-34 0.62
PRIO_SHEEP PRNP Major prion protein 4.931e-33 0.38
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 5.433e-33 0.34
DRD4_HUMAN DRD4 D(4) dopamine receptor 6.444e-33 0.39
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.404e-32 0.39
INHBA_MOUSE Inhba Inhibin beta A chain 3.217e-32 0.34
ACES_MOUSE Ache Acetylcholinesterase 9.54e-31 0.34
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.142e-30 0.39
EGFR_HUMAN EGFR Epidermal growth factor receptor 8.153e-30 0.39
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 8.297e-30 0.39
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.328e-29 0.38
HDAC1_HUMAN HDAC1 Histone deacetylase 1 6.698e-29 0.41
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.757e-28 0.36
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 6.182e-26 0.56
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 2.033e-25 0.35
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 4.828e-25 0.44
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.33e-24 0.36
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 4.567e-24 0.39
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 9.893e-24 0.39
LEF1_HUMAN LEF1 Lymphoid enhancer-binding factor 1 1.444e-23 0.29
TSHR_HUMAN TSHR Thyrotropin receptor 2.208e-23 0.32
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.177e-23 0.35
AAPK2_HUMAN PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 3.069e-22 0.33
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 3.154e-22 0.31
FGF2_HUMAN FGF2 Fibroblast growth factor 2 5.823e-22 0.35
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.007e-21 0.40
AUKBA_XENLA aurkb-a Aurora kinase B-A 4.268e-21 0.34
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 7.013e-21 0.35
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 7.924e-20 0.35
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 8.089e-20 0.36
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 1.714e-19 0.39
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.264e-19 0.34
ASF1A_HUMAN ASF1A Histone chaperone ASF1A 3.915e-19 0.30
MET_HUMAN MET Hepatocyte growth factor receptor 1.339e-18 0.38
FAK1_HUMAN PTK2 Focal adhesion kinase 1 2.345e-18 0.36
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.929e-18 0.39
DGAT1_HUMAN DGAT1 Diacylglycerol O-acyltransferase 1 3.991e-18 0.35
BCR_HUMAN BCR Breakpoint cluster region protein 4.879e-18 0.29
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 8.711e-18 0.35
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 1.601e-17 0.35
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.04e-17 0.36
BRPF1_HUMAN BRPF1 Peregrin 2.547e-17 0.30
OX2R_HUMAN HCRTR2 Orexin receptor type 2 2.782e-17 0.40
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.142e-17 0.38
OX1R_HUMAN HCRTR1 Orexin receptor type 1 3.611e-17 0.40
PLD1_HUMAN PLD1 Phospholipase D1 1.11e-16 0.34
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.331e-16 0.36
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 3.331e-16 0.35
HRH3_CAVPO HRH3 Histamine H3 receptor 6.661e-16 0.37
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 6.661e-16 0.39
DRD3_RAT Drd3 D(3) dopamine receptor 7.772e-16 0.38
HDAC2_HUMAN HDAC2 Histone deacetylase 2 8.882e-16 0.38
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 1.221e-15 0.34
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.554e-15 0.39
ACES_ELEEL ache Acetylcholinesterase 1.998e-15 0.35
O97467_PLAFA ht1 Hexose transporter 1 2.22e-15 0.37
PLD2_HUMAN PLD2 Phospholipase D2 2.665e-15 0.33
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 2.665e-15 0.33
O61059_LEIME LmGT2 Glucose transporter 2.887e-15 0.37
DGAT1_MOUSE Dgat1 Diacylglycerol O-acyltransferase 1 4.663e-15 0.34
CHLE_HORSE BCHE Cholinesterase 5.107e-15 0.38
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.218e-15 0.37
HRH1_CAVPO HRH1 Histamine H1 receptor 5.218e-15 0.33
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 9.548e-15 0.29
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.021e-14 0.39
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.743e-14 0.34
HRH2_CAVPO HRH2 Histamine H2 receptor 2.642e-14 0.34
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.653e-14 0.40
HRH2_HUMAN HRH2 Histamine H2 receptor 3.331e-14 0.39
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 7.649e-14 0.39
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.055e-13 0.31
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.178e-13 0.34
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 1.588e-13 0.33
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.712e-13 0.35
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 1.792e-13 0.30
BMX_HUMAN BMX Cytoplasmic tyrosine-protein kinase BMX 2.452e-13 0.31
ALK_HUMAN ALK ALK tyrosine kinase receptor 2.499e-13 0.35
DRD2_RAT Drd2 D(2) dopamine receptor 2.577e-13 0.38
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 3.854e-13 0.35
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 4.301e-13 0.39
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 5.802e-13 0.35
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 1.898e-12 0.33
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2.515e-12 0.39
GYRB_STAAU gyrB DNA gyrase subunit B 2.589e-12 0.33
HPSE_HUMAN HPSE Heparanase 2.85e-12 0.39
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 3.319e-12 0.30
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 3.863e-12 0.36
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.065e-12 0.39
ACES_RAT Ache Acetylcholinesterase 5.603e-12 0.36
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 6.507e-12 0.31
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 9.035e-12 0.32
ACES_HUMAN ACHE Acetylcholinesterase 9.532e-12 0.38
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 1.029e-11 0.34
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 1.23e-11 0.28
STABP_HUMAN STAMBP STAM-binding protein 2.821e-11 0.32
FA12_HUMAN F12 Coagulation factor XII 3.342e-11 0.32
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 3.37e-11 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 5.685e-11 0.30
RCOR1_HUMAN RCOR1 REST corepressor 1 6.684e-11 0.30
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 8.819e-11 0.39
AURKA_HUMAN AURKA Aurora kinase A 1.11e-10 0.34
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.324e-10 0.39
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.39e-10 0.28
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 1.477e-10 0.39
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 1.522e-10 0.34
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 1.628e-10 0.32
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 2.132e-10 0.35
O96526_LEIMA CRK3 Cdc2-related kinase 2.659e-10 0.30
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 3.189e-10 0.41
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 3.382e-10 0.30
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 5.986e-10 0.32
WDR48_HUMAN WDR48 WD repeat-containing protein 48 6.978e-10 0.31
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 8.518e-10 0.32
RXFP1_HUMAN RXFP1 Relaxin receptor 1 9.216e-10 0.31
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.04e-09 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 1.174e-09 0.36
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 1.189e-09 0.36
AURKB_HUMAN AURKB Aurora kinase B 1.256e-09 0.34
SMS2_HUMAN SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 1.354e-09 0.32
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.502e-09 0.34
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.615e-09 0.36
ACHP_LYMST Acetylcholine-binding protein 1.753e-09 0.30
AKT2_HUMAN AKT2 RAC-beta serine/threonine-protein kinase 2.307e-09 0.34
ISPT_STRPN uppS Isoprenyl transferase 3.389e-09 0.30
CCR1_MOUSE Ccr1 C-C chemokine receptor type 1 3.648e-09 0.29
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 3.719e-09 0.37
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 3.822e-09 0.39
PGFRB_RAT Pdgfrb Platelet-derived growth factor receptor beta 3.823e-09 0.39
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 4.331e-09 0.40
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 4.544e-09 0.36
HS90A_HUMAN HSP90AA1 Heat shock protein HSP 90-alpha 5.834e-09 0.33
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 5.836e-09 0.35
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 6.429e-09 0.32
PARE_STAAU parE DNA topoisomerase 4 subunit B 7.134e-09 0.32
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 7.286e-09 0.39
SHH_MOUSE Shh Sonic hedgehog protein 7.707e-09 0.33
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 7.871e-09 0.39
ACES_BOVIN ACHE Acetylcholinesterase 9.051e-09 0.35
G3I1B6_CRIGR 5-hydroxytryptamine receptor 1.004e-08 0.30
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.201e-08 0.29
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 1.401e-08 0.35
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 1.404e-08 0.35
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 1.412e-08 0.31
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.525e-08 0.34
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 1.558e-08 0.32
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.69e-08 0.32
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 1.772e-08 0.39
SMO_HUMAN SMO Smoothened homolog 1.98e-08 0.41
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 4.076e-08 0.37
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 4.314e-08 0.29
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 5.762e-08 0.32
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 6.406e-08 0.39
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 7.165e-08 0.36
BLK_HUMAN BLK Tyrosine-protein kinase Blk 7.415e-08 0.39
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 9.474e-08 0.39
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 9.945e-08 0.36
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.116e-07 0.39
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 1.146e-07 0.39
FA10_HUMAN F10 Coagulation factor X 1.157e-07 0.33
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 1.252e-07 0.33
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.285e-07 0.38
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 1.424e-07 0.30
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 1.447e-07 0.34
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 1.494e-07 0.35
Q17SB2_PLAFA Plasmepsin 4 1.511e-07 0.29
GYRA_STAAU gyrA DNA gyrase subunit A 2.566e-07 0.33
FAS_HUMAN FASN Fatty acid synthase 2.628e-07 0.36
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 4.172e-07 0.34
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 4.814e-07 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.136e-07 0.34
GALR3_HUMAN GALR3 Galanin receptor type 3 5.708e-07 0.37
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 7.057e-07 0.38
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 7.169e-07 0.37
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 8.215e-07 0.34
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 9.528e-07 0.35
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 1.011e-06 0.39
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 1.026e-06 0.28
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 1.084e-06 0.35
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 1.12e-06 0.39
IMDH2_HUMAN IMPDH2 Inosine-5'-monophosphate dehydrogenase 2 1.271e-06 0.30
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.274e-06 0.38
AKT1_HUMAN AKT1 RAC-alpha serine/threonine-protein kinase 1.293e-06 0.34
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 1.335e-06 0.33
PE2R1_RAT Ptger1 Prostaglandin E2 receptor EP1 subtype 1.418e-06 0.35
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 1.564e-06 0.29
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 1.77e-06 0.32
LYOX_HUMAN LOX Protein-lysine 6-oxidase 1.778e-06 0.32
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.808e-06 0.30
NR1H4_HUMAN NR1H4 Bile acid receptor 1.824e-06 0.31
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 1.89e-06 0.37
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 2.066e-06 0.37
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 2.085e-06 0.39
VACHT_TETCF Vesicular acetylcholine transporter 2.196e-06 0.31
EGLN1_HUMAN EGLN1 Egl nine homolog 1 2.252e-06 0.30
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.296e-06 0.39
Q8IL11_PLAF7 M17 leucyl aminopeptidase 2.368e-06 0.35
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 2.676e-06 0.32
CCNA1_HUMAN CCNA1 Cyclin-A1 2.68e-06 0.31
CHLE_HUMAN BCHE Cholinesterase 2.733e-06 0.32
PGK1_HUMAN PGK1 Phosphoglycerate kinase 1 2.734e-06 0.29
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 2.793e-06 0.35
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 2.867e-06 0.28
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 3.151e-06 0.39
FOS_HUMAN FOS Proto-oncogene c-Fos 3.252e-06 0.29
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 3.371e-06 0.32
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 3.998e-06 0.30
V2R_RAT Avpr2 Vasopressin V2 receptor 4.263e-06 0.35
WDR5_HUMAN WDR5 WD repeat-containing protein 5 4.671e-06 0.35
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.441e-06 0.37
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 5.551e-06 0.31
FKBP4_HUMAN FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4 7.332e-06 0.30
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 7.441e-06 0.34
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 8.059e-06 0.33
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 8.32e-06 0.39
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 8.359e-06 0.28
OGA_HUMAN OGA Protein O-GlcNAcase 9.803e-06 0.34
TRPM5_HUMAN TRPM5 Transient receptor potential cation channel subfamily M member 5 9.855e-06 0.31