Results of Job: search_934d5bcd-90da-49c3-a9b3-693a55a025d9

Query Target Key Target Name Description P-Value MaxTC

compound_1

HRH3_HUMAN HRH3 Histamine H3 receptor 1.746e-165 0.74
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.45e-165 0.51
DRD2_MOUSE Drd2 D(2) dopamine receptor 2.793e-141 0.51
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 3.396e-133 0.58
HRH3_RAT Hrh3 Histamine H3 receptor 3.252e-117 0.49
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 3.26e-117 0.68
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 7.311e-111 0.71
ACES_MOUSE Ache Acetylcholinesterase 2.652e-107 0.43
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 3.257e-97 0.61
HRH1_HUMAN HRH1 Histamine H1 receptor 3.336e-97 0.57
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.074e-94 0.66
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.68e-85 0.57
HRH3_CAVPO HRH3 Histamine H3 receptor 6.398e-82 0.66
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.206e-79 0.66
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.199e-78 0.33
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 5.965e-76 0.61
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 9.659e-76 0.86
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.308e-75 0.63
HRH2_HUMAN HRH2 Histamine H2 receptor 1.591e-74 0.45
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.633e-74 0.58
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 8.447e-72 0.44
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 1.29e-65 0.48
ACES_ELEEL ache Acetylcholinesterase 4.378e-64 0.55
CHLE_HORSE BCHE Cholinesterase 3.991e-63 0.55
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 8.242e-60 0.41
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.119e-58 0.50
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 1.846e-58 0.39
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.838e-57 0.42
HRH3_MOUSE Hrh3 Histamine H3 receptor 7.408e-56 0.58
MEN1_HUMAN MEN1 Menin 2.978e-52 0.45
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 3.135e-52 0.50
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.868e-52 0.66
NORA_STAAU norA Quinolone resistance protein NorA 1.998e-51 0.41
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 3.629e-50 0.57
HRH1_CAVPO HRH1 Histamine H1 receptor 6.356e-50 0.49
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 5.56e-47 0.45
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.65e-47 0.57
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.057e-46 0.51
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.64e-46 0.66
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 5.447e-46 0.40
DRD2_RAT Drd2 D(2) dopamine receptor 1.428e-45 0.56
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.936e-45 0.61
ACES_HUMAN ACHE Acetylcholinesterase 1.098e-44 0.60
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 5.451e-44 0.41
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 1.973e-43 0.34
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 1.973e-43 0.34
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 3.942e-43 0.40
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 5.724e-43 0.33
DRD4_HUMAN DRD4 D(4) dopamine receptor 9.824e-43 0.52
HNMT_RAT Hnmt Histamine N-methyltransferase 1.583e-42 0.37
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 2.889e-41 0.33
O19067_PIG N-methyl-D-aspartate receptor 2.89e-41 0.33
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 2.214e-40 0.38
Q2HXR2_TOXGO PNP Purine nucleoside phosphorylase 1.948e-36 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.525e-34 0.50
DRD4_RAT Drd4 D(4) dopamine receptor 6.447e-34 0.57
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 5.881e-32 0.50
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.276e-31 0.52
DRD3_HUMAN DRD3 D(3) dopamine receptor 4.184e-31 0.57
DNM3A_HUMAN DNMT3A DNA (cytosine-5)-methyltransferase 3A 2.919e-30 0.32
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 5.223e-30 0.61
ACES_RAT Ache Acetylcholinesterase 7.568e-30 0.55
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 3.291e-29 0.33
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.95e-28 0.39
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 2.19e-28 0.62
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 2.574e-28 0.42
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.184e-28 0.66
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.211e-28 0.50
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 1.79e-27 0.34
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.262e-27 0.42
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 5.486e-27 0.35
NPY1R_HUMAN NPY1R Neuropeptide Y receptor type 1 7.766e-27 0.52
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 3.085e-26 0.52
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.496e-26 0.61
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 3.122e-25 0.31
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.335e-25 0.45
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 6.007e-25 0.51
CHLE_HUMAN BCHE Cholinesterase 1.103e-24 0.42
5HT7R_MOUSE Htr7 5-hydroxytryptamine receptor 7 2.158e-24 0.30
DRD5_HUMAN DRD5 D(1B) dopamine receptor 3.468e-24 0.49
KCNJ3_RAT Kcnj3 G protein-activated inward rectifier potassium channel 1 3.815e-24 0.34
KCNJ5_RAT Kcnj5 G protein-activated inward rectifier potassium channel 4 3.815e-24 0.34
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 1.343e-23 0.42
HRH2_CAVPO HRH2 Histamine H2 receptor 1.959e-23 0.36
NPY1R_RAT Npy1r Neuropeptide Y receptor type 1 2.847e-23 0.29
Q6RY99_RAT Tetraspanin 1.109e-22 0.33
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 3.117e-22 0.50
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 4.7e-22 0.54
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 6.238e-22 0.50
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.277e-22 0.50
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 9.872e-22 0.57
ESR1_HUMAN ESR1 Estrogen receptor 1.926e-20 0.35
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 2.485e-20 0.42
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.924e-20 0.42
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 3.117e-20 0.45
EBPL_HUMAN EBPL Emopamil-binding protein-like 3.462e-20 0.32
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.16e-19 0.50
NR1D2_HUMAN NR1D2 Nuclear receptor subfamily 1 group D member 2 1.375e-19 0.31
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 4.211e-19 0.33
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 5.577e-19 0.45
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 5.826e-19 0.40
ADA1A_MOUSE Adra1a Alpha-1A adrenergic receptor 6.741e-19 0.30
ADA1D_MOUSE Adra1d Alpha-1D adrenergic receptor 6.741e-19 0.30
ACHP_LYMST Acetylcholine-binding protein 9.699e-19 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 1.211e-18 0.35
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.197e-17 0.50
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.697e-17 0.34
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 1.11e-16 0.48
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.11e-16 0.38
RYR2_HUMAN RYR2 Ryanodine receptor 2 1.11e-16 0.40
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 2.22e-16 0.36
DRD1_BOVIN DRD1 D(1A) dopamine receptor 3.331e-16 0.31
Q9HUN3_PSEAE dnaB Replicative DNA helicase 3.331e-16 0.36
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 4.441e-16 0.36
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 5.551e-16 0.31
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 5.551e-16 0.55
ADA1B_MOUSE Adra1b Alpha-1B adrenergic receptor 8.882e-16 0.30
DRD3_MOUSE Drd3 D(3) dopamine receptor 8.882e-16 0.30
NK2R_HUMAN TACR2 Substance-K receptor 1.332e-15 0.39
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.443e-15 0.86
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.109e-15 0.41
RORB_RAT Rorb Nuclear receptor ROR-beta 2.776e-15 0.29
A5A4K8_RABIT MLNR Motilin receptor 3.109e-15 0.32
Q9WTR4_RAT Slc6a2 Transporter 5.107e-15 0.39
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 6.883e-15 0.42
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 7.216e-15 0.37
UR2R_HUMAN UTS2R Urotensin-2 receptor 9.659e-15 0.35
MGLL_HUMAN MGLL Monoglyceride lipase 1.288e-14 0.47
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.321e-14 0.43
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 2.065e-14 0.55
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 2.487e-14 0.42
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.72e-14 0.49
OPRX_MOUSE Oprl1 Nociceptin receptor 4.43e-14 0.31
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 6.706e-14 0.38
ERG2_YEAST ERG2 C-8 sterol isomerase 7.128e-14 0.41
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 9.37e-14 0.50
MIP_LEGPN mip Outer membrane protein MIP 9.781e-14 0.33
CASB_RAT Csn2 Beta-casein 1.131e-13 0.30
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 2.801e-13 0.34
TLR9_HUMAN TLR9 Toll-like receptor 9 4.994e-13 0.39
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.089e-12 0.31
VACHT_TETCF Vesicular acetylcholine transporter 1.271e-12 0.36
DRD1_MOUSE Drd1 D(1A) dopamine receptor 2.727e-12 0.39
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 2.757e-12 0.30
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 3.875e-12 0.45
KDM4B_HUMAN KDM4B Lysine-specific demethylase 4B 5.508e-12 0.36
Q4Q5W4_LEIMA Putative squalene synthase 5.582e-12 0.35
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 5.776e-12 0.29
Q63380_RAT NET Transporter 8.811e-12 0.37
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.127e-11 0.42
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 1.29e-11 0.37
CCR5_MOUSE Ccr5 C-C chemokine receptor type 5 2.46e-11 0.34
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.018e-11 0.42
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 4.554e-11 0.50
UPP1_HUMAN UPP1 Uridine phosphorylase 1 7.435e-11 0.32
PYGL_RAT Pygl Glycogen phosphorylase, liver form 9.765e-11 0.31
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.018e-10 0.40
O97467_PLAFA ht1 Hexose transporter 1 1.111e-10 0.44
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.192e-10 0.30
ACHB2_RAT Chrnb2 Neuronal acetylcholine receptor subunit beta-2 1.231e-10 0.42
O61059_LEIME LmGT2 Glucose transporter 1.319e-10 0.44
PPCE_MOUSE Prep Prolyl endopeptidase 1.647e-10 0.28
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 1.681e-10 0.37
AMP1_PLAFQ M1 family aminopeptidase 1.706e-10 0.39
GP183_MOUSE Gpr183 G-protein coupled receptor 183 2.061e-10 0.30
ACHA4_RAT Chrna4 Neuronal acetylcholine receptor subunit alpha-4 2.285e-10 0.42
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 2.634e-10 0.39
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 3.629e-10 0.36
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 4.27e-10 0.32
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 5.47e-10 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.118e-10 0.45
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 8.292e-10 0.35
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 9.336e-10 0.30
ACES_ANOGA Ace Acetylcholinesterase 1.131e-09 0.34
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 1.135e-09 0.34
PA24A_BOVIN PLA2G4A Cytosolic phospholipase A2 1.798e-09 0.29
CASP9_HUMAN CASP9 Caspase-9 2.733e-09 0.32
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 3.595e-09 0.35
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.598e-09 0.29
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 3.652e-09 0.41
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 3.807e-09 0.33
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.135e-09 0.51
Q8WSF8_APLCA Soluble acetylcholine receptor 5.036e-09 0.29
PPCE_BOVIN PREP Prolyl endopeptidase 5.048e-09 0.28
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 5.367e-09 0.30
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 5.553e-09 0.44
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 7.762e-09 0.39
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 7.985e-09 0.35
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 8.47e-09 0.41
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 8.863e-09 0.34
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.972e-08 0.41
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 2.505e-08 0.38
LIPE_MOUSE Lipg Endothelial lipase 2.532e-08 0.29
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.632e-08 0.30
NK3R_CAVPO TACR3 Neuromedin-K receptor 3.878e-08 0.29
CASP2_HUMAN CASP2 Caspase-2 4.226e-08 0.32
CXCR1_HUMAN CXCR1 C-X-C chemokine receptor type 1 4.268e-08 0.40
DRD3_CHLAE DRD3 D(3) dopamine receptor 4.675e-08 0.28
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 5.583e-08 0.38
CASP7_HUMAN CASP7 Caspase-7 8.537e-08 0.32
ACES_BOVIN ACHE Acetylcholinesterase 1.086e-07 0.36
MET_HUMAN MET Hepatocyte growth factor receptor 1.107e-07 0.39
ACHA6_RAT Chrna6 Neuronal acetylcholine receptor subunit alpha-6 1.507e-07 0.30
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 2.004e-07 0.30
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 3.038e-07 0.35
5HT2A_MOUSE Htr2a 5-hydroxytryptamine receptor 2A 4.707e-07 0.30
DRD3_RAT Drd3 D(3) dopamine receptor 4.796e-07 0.32
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 5.031e-07 0.31
Q865E1_MACMU HRH3 Histamine receptor H3 5.745e-07 0.33
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 6.003e-07 0.38
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 6.023e-07 0.30
ACRO_PIG ACR Acrosin 6.334e-07 0.33
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 6.83e-07 0.29
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 8.215e-07 0.44
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.205e-07 0.31
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 9.639e-07 0.34
GYRB_MYCSM gyrB DNA gyrase subunit B 1.004e-06 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.065e-06 0.34
HRH1_RAT Hrh1 Histamine H1 receptor 1.066e-06 0.42
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 1.398e-06 0.36
OPRX_HUMAN OPRL1 Nociceptin receptor 1.517e-06 0.36
DRD1_RAT Drd1 D(1A) dopamine receptor 1.585e-06 0.38
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.829e-06 0.42
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.86e-06 0.39
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.88e-06 0.34
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 2.049e-06 0.29
ITB3_HUMAN ITGB3 Integrin beta-3 2.317e-06 0.39
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 2.509e-06 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.521e-06 0.29
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.735e-06 0.30
DRD1_PIG DRD1 D(1A) dopamine receptor 3.168e-06 0.30
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 3.628e-06 0.31
DRD4_MOUSE Drd4 D(4) dopamine receptor 3.933e-06 0.30
ACES_TETCF ache Acetylcholinesterase 4.025e-06 0.35
OPRM_RAT Oprm1 Mu-type opioid receptor 4.072e-06 0.40
Q72874_9HIV1 pol Pol polyprotein 4.725e-06 0.39
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 5.207e-06 0.37
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 5.463e-06 0.28
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 6.007e-06 0.35
CALCA_HUMAN CALCA Calcitonin gene-related peptide 1 6.189e-06 0.37
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 7.273e-06 0.37
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 8e-06 0.36
OPRM_HUMAN OPRM1 Mu-type opioid receptor 8.896e-06 0.41