Results of Job: search_946f8ad9-eea5-4dc9-afb2-f757e5a9d1cb

Query Target Key Target Name Description P-Value MaxTC

compound_1

GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 1.427e-149 0.36
VE1_HPV11 E1 Replication protein E1 6.154e-146 0.49
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 2.7e-134 0.65
CRTM_STAAU crtM 4,4'-diapophytoene synthase 5.583e-118 0.45
GPR34_MOUSE Gpr34 Probable G-protein coupled receptor 34 3.513e-111 0.35
FFAR1_RAT Ffar1 Free fatty acid receptor 1 4.788e-94 0.41
AOFB_RAT Maob Amine oxidase [flavin-containing] B 5.693e-86 0.37
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 2.301e-75 0.36
P2Y10_MOUSE P2ry10 Putative P2Y purinoceptor 10 5.94e-70 0.35
O68720_YERPE yopH Targeted effector protein 3.353e-68 0.40
EGLN2_HUMAN EGLN2 Egl nine homolog 2 3.65e-65 0.34
MMP13_HUMAN MMP13 Collagenase 3 3.09e-62 0.44
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 8.336e-62 0.31
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 3.794e-61 0.46
EPOR_HUMAN EPOR Erythropoietin receptor 2.728e-60 0.34
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 1.687e-54 0.47
MMP2_HUMAN MMP2 72 kDa type IV collagenase 6.154e-54 0.47
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 6.98e-54 0.47
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 2.692e-53 0.40
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.239e-52 0.44
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 7.808e-52 0.47
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 2.031e-50 0.42
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 8.316e-50 0.37
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 1.178e-48 0.38
FDFT_HUMAN FDFT1 Squalene synthase 1.374e-48 0.43
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 1.597e-48 0.40
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 1.113e-44 0.42
PHHY_PSEFL pobA p-hydroxybenzoate hydroxylase 1.353e-43 0.35
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 2.271e-42 0.35
MMP1_HUMAN MMP1 Interstitial collagenase 2.342e-42 0.45
PDS_SYNE7 pds 15-cis-phytoene desaturase 3.45e-42 0.31
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 3.923e-42 0.64
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 1.03e-41 0.42
CETP_RABIT CETP Cholesteryl ester transfer protein 1.76e-41 0.44
NR1H2_MOUSE Nr1h2 Oxysterols receptor LXR-beta 6.964e-40 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 2.806e-39 0.40
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 8.103e-39 0.34
KAT1_HUMAN KYAT1 Kynurenine--oxoglutarate transaminase 1 1.579e-38 0.31
FFAR1_MACFA FFAR1 Free fatty acid receptor 1 9.681e-38 0.30
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 3.587e-37 0.30
MMP3_HUMAN MMP3 Stromelysin-1 3.136e-35 0.43
ADA17_MOUSE Adam17 Disintegrin and metalloproteinase domain-containing protein 17 5.282e-35 0.31
KLK_PIG Glandular kallikrein 1.396e-32 0.39
PTPRZ_HUMAN PTPRZ1 Receptor-type tyrosine-protein phosphatase zeta 2.828e-31 0.39
AMP1_PLAFQ M1 family aminopeptidase 1.055e-30 0.38
Q9RMI3_STAAU fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] 4.985e-30 0.33
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 5.651e-30 0.37
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 3.467e-29 0.33
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 3.86e-29 0.37
MDHM_PIG MDH2 Malate dehydrogenase, mitochondrial 2.198e-28 0.38
ACRO_PIG ACR Acrosin 3.872e-28 0.37
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 4.751e-28 0.40
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 7.275e-28 0.40
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.14e-27 0.44
Q6RY99_RAT Tetraspanin 1.15e-27 0.39
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 1.032e-26 0.41
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.145e-26 0.41
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 1.142e-25 0.41
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.398e-25 0.39
NMDZ1_HUMAN GRIN1 Glutamate receptor ionotropic, NMDA 1 1.346e-24 0.39
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 2.319e-24 0.39
MMP12_MOUSE Mmp12 Macrophage metalloelastase 2.631e-24 0.30
MMP8_HUMAN MMP8 Neutrophil collagenase 2.679e-24 0.43
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.836e-23 0.40
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 3.897e-23 0.47
THA_HUMAN THRA Thyroid hormone receptor alpha 2.081e-22 0.33
SIR3_HUMAN SIRT3 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 2.727e-22 0.33
CLTR1_CAVPO CYSLTR1 Cysteinyl leukotriene receptor 1 9.11e-22 0.39
MGLL_MOUSE Mgll Monoglyceride lipase 4.016e-21 0.37
EGLN1_HUMAN EGLN1 Egl nine homolog 1 6.115e-21 0.34
DGLA_MOUSE Dagla Sn1-specific diacylglycerol lipase alpha 1.073e-20 0.41
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.202e-20 0.30
MMP7_HUMAN MMP7 Matrilysin 1.385e-20 0.40
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 1.464e-20 0.31
ADA17_RAT Adam17 Disintegrin and metalloproteinase domain-containing protein 17 1.976e-20 0.28
GP183_MOUSE Gpr183 G-protein coupled receptor 183 2.333e-20 0.31
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 3.311e-20 0.31
FFAR4_MOUSE Ffar4 Free fatty acid receptor 4 3.88e-20 0.39
NTCP_RAT Slc10a1 Sodium/bile acid cotransporter 4.955e-20 0.32
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 7.006e-20 0.39
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 8.656e-20 0.31
THB_HUMAN THRB Thyroid hormone receptor beta 1.34e-19 0.33
O39930_9HEPC NS5b RNA-directed RNA polymerase 2.313e-19 0.37
KAT3_HUMAN KYAT3 Kynurenine--oxoglutarate transaminase 3 3.333e-19 0.31
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 5.093e-19 0.41
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 9.793e-19 0.37
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.053e-18 0.34
SPHK2_HUMAN SPHK2 Sphingosine kinase 2 1.692e-18 0.39
SENP1_HUMAN SENP1 Sentrin-specific protease 1 1.992e-18 0.31
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 2.153e-18 0.35
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 5.247e-18 0.31
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.561e-17 0.35
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 2.817e-17 0.39
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 2.85e-17 0.31
MGLL_HUMAN MGLL Monoglyceride lipase 2.859e-17 0.40
PTGES_MOUSE Ptges Prostaglandin E synthase 3.088e-17 0.38
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 3.345e-17 0.44
AAAT_HUMAN SLC1A5 Neutral amino acid transporter B(0) 1.11e-16 0.32
AOFA_HUMAN MAOA Amine oxidase [flavin-containing] A 1.11e-16 0.36
SPHK1_MOUSE Sphk1 Sphingosine kinase 1 1.11e-16 0.32
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.331e-16 0.31
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 5.551e-16 0.40
FDFT_RAT Fdft1 Squalene synthase 1.11e-15 0.40
CATL2_HUMAN CTSV Cathepsin L2 2.109e-15 0.37
Q25615_ONCVO Chitinase 2.665e-15 0.34
MMP12_HUMAN MMP12 Macrophage metalloelastase 3.442e-15 0.40
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 2.787e-14 0.35
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 3.753e-14 0.40
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 4.896e-14 0.37
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 5.029e-14 0.33
MMP13_RAT Mmp13 Collagenase 3 5.429e-14 0.29
LPXC_PSEAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.494e-14 0.36
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 7.86e-14 0.31
DPYD_HUMAN DPYD Dihydropyrimidine dehydrogenase [NADP(+)] 8.893e-14 0.34
GRM2_RAT Grm2 Metabotropic glutamate receptor 2 1.052e-13 0.37
KCNA3_MOUSE Kcna3 Potassium voltage-gated channel subfamily A member 3 1.331e-13 0.30
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 2.075e-13 0.37
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 2.518e-13 0.33
Q93EK7_NEIME lgtC LgtC 3.164e-13 0.29
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 5.305e-13 0.35
EDNRA_RAT Ednra Endothelin-1 receptor 5.649e-13 0.39
A85C_MYCTU fbpC Diacylglycerol acyltransferase/mycolyltransferase Ag85C 8.148e-13 0.38
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 9.167e-13 0.31
MCL1_MOUSE Mcl1 Induced myeloid leukemia cell differentiation protein Mcl-1 homolog 1.079e-12 0.29
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 1.123e-12 0.41
PIR_HUMAN PIR Pirin 1.303e-12 0.37
PNPH_RAT Pnp Purine nucleoside phosphorylase 1.938e-12 0.33
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 2.143e-12 0.37
GPR18_HUMAN GPR18 N-arachidonyl glycine receptor 2.822e-12 0.30
PRGR_HUMAN PGR Progesterone receptor 3.771e-12 0.40
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 3.875e-12 0.35
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 4.52e-12 0.33
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.312e-12 0.41
TIF1A_HUMAN TRIM24 Transcription intermediary factor 1-alpha 1.332e-11 0.35
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 1.769e-11 0.37
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.881e-11 0.40
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.904e-11 0.41
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.272e-11 0.30
CAH9_HUMAN CA9 Carbonic anhydrase 9 2.517e-11 0.48
CBPA1_HUMAN CPA1 Carboxypeptidase A1 2.924e-11 0.34
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 3.357e-11 0.34
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 4.48e-11 0.32
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 4.5e-11 0.41
Q9Z1J7_RAT Slc1a5 Amino acid transporter 4.775e-11 0.32
UPP1_HUMAN UPP1 Uridine phosphorylase 1 4.775e-11 0.32
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 6.764e-11 0.33
MOT4_HUMAN SLC16A3 Monocarboxylate transporter 4 9.837e-11 0.34
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 1.094e-10 0.37
Q4Q5W4_LEIMA Putative squalene synthase 1.25e-10 0.31
PMT1_CANAL PMT1 Dolichyl-phosphate-mannose--protein mannosyltransferase 1 1.763e-10 0.32
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.284e-10 0.48
ACACA_HUMAN ACACA Acetyl-CoA carboxylase 1 2.668e-10 0.36
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 3.892e-10 0.37
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.439e-10 0.48
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.972e-10 0.48
HISX_BRUSU hisD Histidinol dehydrogenase 6.158e-10 0.33
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 7.541e-10 0.29
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.069e-09 0.48
GCR_RAT Nr3c1 Glucocorticoid receptor 1.729e-09 0.36
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 1.825e-09 0.38
AROK_HELPY aroK Shikimate kinase 2.304e-09 0.29
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 3.07e-09 0.41
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 3.243e-09 0.34
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 3.313e-09 0.36
PA_I34A1 PA Polymerase acidic protein 3.363e-09 0.41
ANO1_HUMAN ANO1 Anoctamin-1 3.553e-09 0.31
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 4.18e-09 0.33
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 4.214e-09 0.38
AROC_STRPN aroC Chorismate synthase 4.318e-09 0.36
LUCI_RENRE Coelenterazine h 2-monooxygenase 4.353e-09 0.32
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 4.829e-09 0.30
MEP1B_HUMAN MEP1B Meprin A subunit beta 7.272e-09 0.30
P2Y14_MOUSE P2ry14 P2Y purinoceptor 14 7.288e-09 0.34
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 9.133e-09 0.32
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 9.701e-09 0.42
THRB_BOVIN F2 Prothrombin 9.809e-09 0.39
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.036e-08 0.32
STS_HUMAN STS Steryl-sulfatase 1.119e-08 0.34
MMP10_HUMAN MMP10 Stromelysin-2 1.438e-08 0.37
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 1.449e-08 0.32
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 1.62e-08 0.37
B2CL1_HUMAN BCL2L1 Bcl-2-like protein 1 1.627e-08 0.41
GP183_HUMAN GPR183 G-protein coupled receptor 183 1.963e-08 0.31
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 2.002e-08 0.34
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 2.081e-08 0.33
A5H660_SCHMA HDAC8 Histone deacetylase 8 2.146e-08 0.33
Q7ZJM1_9HIV1 pol Integrase 2.229e-08 0.42
EST1_HUMAN CES1 Liver carboxylesterase 1 2.279e-08 0.34
CETP_HUMAN CETP Cholesteryl ester transfer protein 3.043e-08 0.43
LPAR1_HUMAN LPAR1 Lysophosphatidic acid receptor 1 3.141e-08 0.32
XBP1_HUMAN XBP1 X-box-binding protein 1 3.318e-08 0.43
FFAR1_MOUSE Ffar1 Free fatty acid receptor 1 3.386e-08 0.35
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 3.936e-08 0.39
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 4.043e-08 0.31
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 4.117e-08 0.35
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 4.181e-08 0.37
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 4.895e-08 0.38
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 6.502e-08 0.30
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 9.145e-08 0.30
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 9.633e-08 0.30
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 9.948e-08 0.46
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 1.215e-07 0.38
NAC1_HUMAN SLC8A1 Sodium/calcium exchanger 1 1.691e-07 0.30
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 1.848e-07 0.33
PACR_HUMAN ADCYAP1R1 Pituitary adenylate cyclase-activating polypeptide type I receptor 2.457e-07 0.31
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 4.312e-07 0.32
FEN1_HUMAN FEN1 Flap endonuclease 1 4.546e-07 0.39
F13A_HUMAN F13A1 Coagulation factor XIII A chain 4.559e-07 0.41
PTN9_HUMAN PTPN9 Tyrosine-protein phosphatase non-receptor type 9 5.06e-07 0.30
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 5.425e-07 0.32
TA2R_MOUSE Tbxa2r Thromboxane A2 receptor 5.972e-07 0.30
PE2R2_RAT Ptger2 Prostaglandin E2 receptor EP2 subtype 7.205e-07 0.33
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 7.522e-07 0.37
PI2R_HUMAN PTGIR Prostacyclin receptor 8.524e-07 0.32
LOX15_PIG ALOX15 Arachidonate 15-lipoxygenase 1.166e-06 0.28
F261_HUMAN PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 1.176e-06 0.31
ADA10_HUMAN ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 1.183e-06 0.35
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 1.198e-06 0.28
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 1.272e-06 0.30
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 1.393e-06 0.30
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 1.633e-06 0.32
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.744e-06 0.31
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 1.77e-06 0.33
OXDA_MOUSE Dao D-amino-acid oxidase 1.788e-06 0.31
KLF5_HUMAN KLF5 Krueppel-like factor 5 2.041e-06 0.42
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 2.258e-06 0.33
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 2.26e-06 0.29
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3.396e-06 0.33
PLEC_HUMAN PLEC Plectin 3.811e-06 0.32
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 4.338e-06 0.29
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 4.399e-06 0.31
DPOL_VACCW POL DNA polymerase 4.586e-06 0.30
F262_HUMAN PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 4.793e-06 0.31
TAAR1_RAT Taar1 Trace amine-associated receptor 1 4.96e-06 0.38
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 5.567e-06 0.28
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 5.668e-06 0.30
DDIT3_MOUSE Ddit3 DNA damage-inducible transcript 3 protein 6.181e-06 0.43
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 6.729e-06 0.32
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 8.449e-06 0.35