Results of Job: search_94ec5266-c641-4ecf-9f05-309d20ce5c01

Query Target Key Target Name Description P-Value MaxTC

compound_11

MEP50_HUMAN WDR77 Methylosome protein 50 7.35e-229 0.43
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 3.81e-227 0.43
SCN1A_HUMAN SCN1A Sodium channel protein type 1 subunit alpha 5.073e-87 0.38
SCN9A_MOUSE Scn9a Sodium channel protein type 9 subunit alpha 1.449e-81 0.38
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 4.602e-62 0.33
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 3.309e-61 0.45
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 5.399e-61 0.38
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.756e-55 0.35
Q5YLN7_CANLF SCN5A Voltage-gated sodium channel Nav1.5 cardiac isoform 6.678e-41 0.32
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 7.214e-41 0.36
NAT_MYCSM nat Arylamine N-acetyltransferase 9.26e-40 0.32
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.248e-38 0.36
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 5.307e-25 0.32
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 2e-23 0.29
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 1.193e-22 0.32
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.601e-22 0.33
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 9.475e-22 0.30
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 4.879e-18 0.29
ACHP_LYMST Acetylcholine-binding protein 6.054e-18 0.36
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 4.441e-16 0.30
HS90B_HUMAN HSP90AB1 Heat shock protein HSP 90-beta 2.887e-15 0.37
5HT1B_GORGO HTR1B 5-hydroxytryptamine receptor 1B 5.551e-15 0.28
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 7.461e-14 0.32
MTR1B_CHICK Melatonin receptor type 1B 9.215e-14 0.30
Q5TKS5_STAAU fabI Enoyl-ACP reductase 1.915e-12 0.30
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 6.063e-12 0.36
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.445e-11 0.36
Q6RY99_RAT Tetraspanin 2.119e-11 0.31
CALM_BOVIN CALM Calmodulin 6.343e-11 0.29
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 2.131e-10 0.30
VACHT_TETCF Vesicular acetylcholine transporter 2.859e-10 0.31
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 3.506e-10 0.34
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.117e-09 0.30
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 1.217e-09 0.28
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.431e-09 0.34
PPCE_HUMAN PREP Prolyl endopeptidase 1.748e-09 0.32
HRH1_RAT Hrh1 Histamine H1 receptor 4.523e-09 0.36
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 5.056e-09 0.32
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 5.897e-09 0.30
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 6.879e-09 0.39
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 2.827e-08 0.31
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.894e-08 0.39
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 1.147e-07 0.39
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 1.633e-07 0.37
NORA_STAAU norA Quinolone resistance protein NorA 5.215e-07 0.33
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 5.484e-07 0.36
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 8.305e-07 0.39
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 8.87e-07 0.36
NR1H4_MOUSE Nr1h4 Bile acid receptor 1.054e-06 0.32
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.343e-06 0.31
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.449e-06 0.36
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.489e-06 0.31
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.079e-06 0.31
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.053e-06 0.36

compound_15

ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.243e-193 0.37
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 2.652e-180 0.45
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 1.124e-84 0.38
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 2.165e-78 0.44
ACES_MOUSE Ache Acetylcholinesterase 2.061e-67 0.41
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 3.124e-61 0.36
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 5.073e-58 0.38
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.733e-54 0.37
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.752e-52 0.36
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 1.859e-51 0.38
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 3.537e-46 0.37
CCR1_MOUSE Ccr1 C-C chemokine receptor type 1 2.016e-45 0.34
DRD4_HUMAN DRD4 D(4) dopamine receptor 4.675e-42 0.40
DRD1_BOVIN DRD1 D(1A) dopamine receptor 9.827e-42 0.34
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 6.678e-41 0.32
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 6.678e-41 0.32
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.008e-40 0.37
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 5.657e-40 0.34
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 7.506e-40 0.36
UR2R_MACMU UTS2R Urotensin-2 receptor 1.317e-37 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 6.403e-34 0.43
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.217e-33 0.32
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 4.968e-32 0.35
ACES_RAT Ache Acetylcholinesterase 6.165e-32 0.38
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 7.508e-32 0.34
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 2.423e-31 0.34
CTNB1_HUMAN CTNNB1 Catenin beta-1 5.029e-31 0.32
MTLR_HUMAN MLNR Motilin receptor 1.213e-30 0.33
G3H407_CRIGR PROKR2 2.208e-28 0.34
ACES_HUMAN ACHE Acetylcholinesterase 4.318e-28 0.41
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 6.039e-28 0.42
HRH3_CAVPO HRH3 Histamine H3 receptor 9.487e-28 0.42
OGA_RAT Oga Protein O-GlcNAcase 4.374e-27 0.31
EHMT2_MOUSE Ehmt2 Histone-lysine N-methyltransferase EHMT2 1.158e-26 0.33
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.598e-25 0.34
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 6.397e-25 0.40
GHSR_MOUSE Ghsr Growth hormone secretagogue receptor type 1 2.158e-24 0.30
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 4.098e-23 0.36
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 5.184e-23 0.40
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.853e-22 0.36
VACHT_TETCF Vesicular acetylcholine transporter 3.444e-22 0.32
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 4.65e-22 0.36
ACES_ELEEL ache Acetylcholinesterase 1.819e-21 0.36
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 6.571e-21 0.32
PIM3_HUMAN PIM3 Serine/threonine-protein kinase pim-3 7.404e-21 0.34
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.037e-19 0.33
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 2.196e-19 0.31
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 2.416e-19 0.37
CHLE_HORSE BCHE Cholinesterase 2.665e-19 0.36
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 4.792e-19 0.35
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 6.05e-19 0.39
MIP_LEGPN mip Outer membrane protein MIP 9.157e-19 0.29
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.831e-18 0.30
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 1.965e-18 0.42
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.3e-18 0.34
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 4.34e-18 0.30
TRPC1_HUMAN TRPC1 Short transient receptor potential channel 1 8.104e-18 0.28
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 8.598e-18 0.33
CARP2_CANAX SAP2 Candidapepsin-2 1.928e-17 0.28
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.892e-17 0.40
CHLE_HUMAN BCHE Cholinesterase 2.22e-16 0.34
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 2.22e-16 0.37
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 3.331e-16 0.37
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 7.772e-16 0.32
S1PR5_HUMAN S1PR5 Sphingosine 1-phosphate receptor 5 8.882e-16 0.35
UR2R_HUMAN UTS2R Urotensin-2 receptor 8.882e-16 0.34
PIM2_HUMAN PIM2 Serine/threonine-protein kinase pim-2 2.109e-15 0.34
PA_I000X PA Polymerase acidic protein 2.22e-15 0.29
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 5.551e-15 0.36
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 5.551e-15 0.39
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 9.992e-15 0.32
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 1.177e-14 0.29
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.51e-14 0.34
Q9HUN3_PSEAE dnaB Replicative DNA helicase 2.132e-14 0.32
BRS3_RAT Brs3 Bombesin receptor subtype-3 3.73e-14 0.29
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 5.329e-14 0.36
G3HIE5_CRIGR Prokineticin receptor 1 5.618e-14 0.34
ENV_HV1Y2 env Envelope glycoprotein gp160 8.493e-14 0.30
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 9.681e-14 0.34
S1PR3_HUMAN S1PR3 Sphingosine 1-phosphate receptor 3 1.521e-13 0.34
SC6A3_MACFA SLC6A3 Sodium-dependent dopamine transporter 1.733e-13 0.30
STIM1_RAT Stim1 Stromal interaction molecule 1 2.649e-13 0.36
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 2.801e-13 0.37
HRH1_CAVPO HRH1 Histamine H1 receptor 2.982e-13 0.39
GDIR1_HUMAN ARHGDIA Rho GDP-dissociation inhibitor 1 3.235e-13 0.32
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 3.281e-13 0.37
S1PR1_HUMAN S1PR1 Sphingosine 1-phosphate receptor 1 3.9e-13 0.35
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 3.991e-13 0.35
LX15B_HUMAN ALOX15B Arachidonate 15-lipoxygenase B 4.028e-13 0.32
OPRX_MOUSE Oprl1 Nociceptin receptor 6.588e-13 0.28
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 8.066e-13 0.31
KS6A2_HUMAN RPS6KA2 Ribosomal protein S6 kinase alpha-2 8.733e-13 0.31
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 1.908e-12 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.979e-12 0.40
STIM1_HUMAN STIM1 Stromal interaction molecule 1 2.037e-12 0.36
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 3.239e-12 0.30
A0A059UE90_BOVIN GSK3beta Glycogen synthase kinase-3 beta splice variant X1 5.022e-12 0.32
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 5.723e-12 0.30
ACHP_LYMST Acetylcholine-binding protein 7.211e-12 0.33
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.035e-11 0.40
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 2.67e-11 0.36
FA5_HUMAN F5 Coagulation factor V 4.487e-11 0.30
DRD3_RAT Drd3 D(3) dopamine receptor 4.922e-11 0.36
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.353e-10 0.33
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.585e-10 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 6.511e-10 0.37
Q9JLY8_RAT Ccr1 C-C motif chemokine receptor 1 6.767e-10 0.34
OPRM_RAT Oprm1 Mu-type opioid receptor 6.8e-10 0.34
PIM1_HUMAN PIM1 Serine/threonine-protein kinase pim-1 7.064e-10 0.34
NK2R_HUMAN TACR2 Substance-K receptor 9.057e-10 0.35
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 9.457e-10 0.35
OPRD_HUMAN OPRD1 Delta-type opioid receptor 9.819e-10 0.38
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 1.433e-09 0.37
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 1.511e-09 0.41
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 1.82e-09 0.30
PDE1C_HUMAN PDE1C Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 1.926e-09 0.31
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.376e-09 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 4.155e-09 0.28
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 4.279e-09 0.36
AA2BR_MOUSE Adora2b Adenosine receptor A2b 4.608e-09 0.28
CCNC_HUMAN CCNC Cyclin-C 6.585e-09 0.31
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 7.244e-09 0.30
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 1.573e-08 0.36
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.115e-08 0.30
OPRM_HUMAN OPRM1 Mu-type opioid receptor 3.269e-08 0.38
SMYD2_HUMAN SMYD2 N-lysine methyltransferase SMYD2 3.867e-08 0.29
BACE1_MOUSE Bace1 Beta-secretase 1 4.262e-08 0.29
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 6.882e-08 0.30
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 8.188e-08 0.30
THRB_HUMAN F2 Prothrombin 8.672e-08 0.33
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 1.063e-07 0.32
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 1.232e-07 0.31
IL6_HUMAN IL6 Interleukin-6 1.563e-07 0.29
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.913e-07 0.30
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 2.095e-07 0.33
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 2.169e-07 0.32
MTP_HUMAN MTTP Microsomal triglyceride transfer protein large subunit 2.676e-07 0.34
Q9BRH5_HUMAN DGAT1 DGAT1 protein 2.853e-07 0.31
PANK3_HUMAN PANK3 Pantothenate kinase 3 3.118e-07 0.28
HRH3_HUMAN HRH3 Histamine H3 receptor 3.159e-07 0.41
PA_I34A1 PA Polymerase acidic protein 4.097e-07 0.29
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 5.521e-07 0.30
NK1R_HUMAN TACR1 Substance-P receptor 6.13e-07 0.35
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 7.258e-07 0.30
DRD2_RAT Drd2 D(2) dopamine receptor 7.859e-07 0.36
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 8.736e-07 0.33
PRIO_SHEEP PRNP Major prion protein 1.069e-06 0.31
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.153e-06 0.30
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 1.34e-06 0.30
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.405e-06 0.34
ACES_BOVIN ACHE Acetylcholinesterase 1.448e-06 0.30
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.828e-06 0.39
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.906e-06 0.37
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 2.962e-06 0.31
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 5.176e-06 0.37
CCR5_MACFA CCR5 C-C chemokine receptor type 5 5.752e-06 0.28
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 5.815e-06 0.28
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 6.077e-06 0.31
PPARA_RAT Ppara Peroxisome proliferator-activated receptor alpha 6.845e-06 0.28
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 8.168e-06 0.29
Q9WTR4_RAT Slc6a2 Transporter 8.454e-06 0.39
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 9.719e-06 0.30

compound_6

PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 4.774e-133 0.46
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 7.577e-122 0.46
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.277e-52 0.32
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.346e-51 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 9.444e-51 0.49
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 3.004e-41 0.32
NEP_RAT Mme Neprilysin 3.1e-29 0.32
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 1.895e-28 0.34
ACE_RABIT ACE Angiotensin-converting enzyme 3.91e-27 0.35
MMP9_RAT Mmp9 Matrix metalloproteinase-9 9.204e-27 0.34
CATL1_BOVIN CTSL Cathepsin L1 2.429e-25 0.34
ACE_RAT Ace Angiotensin-converting enzyme 3.657e-25 0.32
ACE_HUMAN ACE Angiotensin-converting enzyme 6.405e-25 0.34
PROC_HUMAN PROC Vitamin K-dependent protein C 5.953e-22 0.33
AMP1_PLAFQ M1 family aminopeptidase 1.023e-21 0.34
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 9.432e-21 0.29
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 1.075e-20 0.33
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 2.137e-19 0.32
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 2.324e-19 0.32
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 8.175e-19 0.36
M9TGV3_MYCTX inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 5.844e-18 0.41
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 7.369e-18 0.33
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 4.134e-17 0.35
PPCE_HUMAN PREP Prolyl endopeptidase 1.11e-16 0.37
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 5.551e-16 0.33
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 3.775e-15 0.38
ENV_HV1H2 env Envelope glycoprotein gp160 7.105e-15 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 7.994e-15 0.32
PAPA1_CARPA Papain 5.196e-14 0.34
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 5.473e-14 0.29
CAC1H_HUMAN CACNA1H Voltage-dependent T-type calcium channel subunit alpha-1H 6.428e-14 0.33
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.044e-13 0.32
TP53B_HUMAN TP53BP1 TP53-binding protein 1 1.242e-13 0.30
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 1.842e-13 0.29
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.846e-13 0.30
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 4.751e-13 0.28
PPCE_PIG PREP Prolyl endopeptidase 2.145e-12 0.36
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.331e-11 0.34
CATS_HUMAN CTSS Cathepsin S 1.621e-11 0.36
CATK_RABIT CTSK Cathepsin K 2.165e-11 0.30
KLKB1_HUMAN KLKB1 Plasma kallikrein 2.177e-11 0.35
THER_BACTH npr Thermolysin 2.246e-11 0.29
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.566e-11 0.38
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 3.03e-11 0.38
RS27_HUMAN RPS27 40S ribosomal protein S27 4.393e-11 0.30
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 6.023e-11 0.29
C3SIU2_ECOLX metJ Met repressor 7.597e-11 0.28
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 7.687e-11 0.38
NEP_RABIT MME Neprilysin 8.704e-11 0.32
NEP_HUMAN MME Neprilysin 1.662e-10 0.32
MCA2_TRYBB MCA2 Metacaspase 3.619e-10 0.30
MAZF_ECOLI mazF Endoribonuclease toxin MazF 5.916e-10 0.41
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.529e-09 0.32
PPCE_BOVIN PREP Prolyl endopeptidase 2.039e-09 0.29
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 2.15e-09 0.29
ISPT_STRPN uppS Isoprenyl transferase 2.576e-09 0.31
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 3.73e-09 0.32
LGMN_HUMAN LGMN Legumain 7.641e-09 0.34
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.187e-08 0.32
AMPN_PIG ANPEP Aminopeptidase N 1.721e-08 0.32
ITA2_HUMAN ITGA2 Integrin alpha-2 2.394e-08 0.30
CATK_HUMAN CTSK Cathepsin K 3.019e-08 0.34
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.754e-08 0.35
O31048_PORGN DPP IV Dipeptidyl peptidase IV 5.622e-08 0.32
PANK3_HUMAN PANK3 Pantothenate kinase 3 5.941e-08 0.31
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 7.902e-08 0.39
CATB_HUMAN CTSB Cathepsin B 8.563e-08 0.32
MMP13_RAT Mmp13 Collagenase 3 9.613e-08 0.30
Q4U254_9ENTO protease Protease 1.044e-07 0.38
CATL1_HUMAN CTSL Cathepsin L1 2.094e-07 0.33
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 3.359e-07 0.30
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 4.838e-07 0.31
AMPN_HUMAN ANPEP Aminopeptidase N 4.894e-07 0.34
ACE_MOUSE Ace Angiotensin-converting enzyme 5.408e-07 0.28
OXYR_RAT Oxtr Oxytocin receptor 7.431e-07 0.30
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 9.613e-07 0.29
EZH1_HUMAN EZH1 Histone-lysine N-methyltransferase EZH1 1.106e-06 0.28
ITB1_HUMAN ITGB1 Integrin beta-1 1.179e-06 0.35
SEPR_MOUSE Fap Prolyl endopeptidase FAP 1.315e-06 0.31
ITA4_HUMAN ITGA4 Integrin alpha-4 1.795e-06 0.35
PEPT1_DERPT DERP1 Peptidase 1 1.812e-06 0.30
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.518e-06 0.33
DPP8_HUMAN DPP8 Dipeptidyl peptidase 8 3.405e-06 0.37
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 4.232e-06 0.32
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.241e-06 0.36
CATC_HUMAN CTSC Dipeptidyl peptidase 1 4.423e-06 0.34
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 5.078e-06 0.40
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 5.293e-06 0.29
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 6.009e-06 0.29
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 6.271e-06 0.30
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 6.909e-06 0.30
TF2AA_HUMAN GTF2A1 Transcription initiation factor IIA subunit 1 7.112e-06 0.29
HDAC6_MOUSE Hdac6 Histone deacetylase 6 7.339e-06 0.30

compound_1

ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.491e-122 0.35
ADA17_MOUSE Adam17 Disintegrin and metalloproteinase domain-containing protein 17 2.291e-91 0.33
DEF_MYCTU def Peptide deformylase 1.933e-86 0.33
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 6.131e-61 0.32
Q1HEC0_RAT Acetyl-Coenzyme A carboxylase 2 4.07e-55 0.31
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 3.241e-50 0.31
ADA17_HUMAN ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4.945e-49 0.35
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 6.254e-47 0.34
OX1R_RAT Hcrtr1 Orexin receptor type 1 1.314e-42 0.35
UTS2_MACMU UTS2 Urotensin-2 5.166e-42 0.33
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 5.689e-42 0.32
SEPR_MOUSE Fap Prolyl endopeptidase FAP 1.814e-41 0.49
OX2R_HUMAN HCRTR2 Orexin receptor type 2 6.662e-41 0.40
PPCE_PIG PREP Prolyl endopeptidase 3.754e-39 0.32
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.769e-37 0.40
ACHA3_MOUSE Chrna3 Neuronal acetylcholine receptor subunit alpha-3 2.707e-37 0.30
CRTY_PANAN crtY Lycopene beta-cyclase 2.707e-37 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 8.021e-34 0.35
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.89e-32 0.35
NK2R_BOVIN TACR2 Substance-K receptor 9.508e-30 0.30
PPCE_HUMAN PREP Prolyl endopeptidase 2.683e-23 0.49
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 5.225e-23 0.28
CCNC_HUMAN CCNC Cyclin-C 2.13e-19 0.41
OXYR_MOUSE Oxtr Oxytocin receptor 3.244e-18 0.29
ACACA_HUMAN ACACA Acetyl-CoA carboxylase 1 2.22e-16 0.34
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 3.331e-16 0.35
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 3.331e-16 0.31
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 5.551e-16 0.31
ADHX_HUMAN ADH5 Alcohol dehydrogenase class-3 6.661e-16 0.35
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 6.661e-16 0.30
SSR3_MOUSE Sstr3 Somatostatin receptor type 3 1.776e-15 0.29
ADA33_HUMAN ADAM33 Disintegrin and metalloproteinase domain-containing protein 33 2.22e-15 0.31
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 7.55e-15 0.33
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.277e-14 0.33
Q9BRH5_HUMAN DGAT1 DGAT1 protein 5.884e-14 0.32
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 5.623e-13 0.41
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 9.813e-13 0.29
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.162e-12 0.37
KCND3_HUMAN KCND3 Potassium voltage-gated channel subfamily D member 3 1.608e-12 0.31
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 2.641e-12 0.35
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 4.021e-12 0.32
FIBB_HUMAN FGB Fibrinogen beta chain 1.397e-11 0.31
COX2_SHEEP MT-CO2 Cytochrome c oxidase subunit 2 2.783e-11 0.30
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 3.332e-11 0.33
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 8.943e-11 0.35
PPCE_RAT Prep Prolyl endopeptidase 2.134e-10 0.31
SYPC_CANAX PRS Proline--tRNA ligase, cytoplasmic 2.676e-10 0.30
GYRB_MYCSM gyrB DNA gyrase subunit B 3.293e-10 0.34
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 1.214e-09 0.39
S12A5_HUMAN SLC12A5 Solute carrier family 12 member 5 1.53e-09 0.29
IF4A3_HUMAN EIF4A3 Eukaryotic initiation factor 4A-III 1.601e-09 0.30
ACHA4_CHICK CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.91e-09 0.30
ACHA9_RAT Chrna9 Neuronal acetylcholine receptor subunit alpha-9 1.91e-09 0.30
FABI_STAA8 fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI 2.518e-09 0.33
ALF_MYCTU fba Fructose-bisphosphate aldolase 3.137e-09 0.42
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.364e-08 0.32
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 6.101e-08 0.30
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 6.732e-08 0.39
PYRD_HUMAN DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial 7.9e-08 0.37
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 8.103e-08 0.32
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.046e-07 0.30
BCL2_HUMAN BCL2 Apoptosis regulator Bcl-2 5.398e-07 0.31
ACHA4_MOUSE Chrna4 Neuronal acetylcholine receptor subunit alpha-4 5.972e-07 0.30
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 6.461e-07 0.34
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 1.608e-06 0.31
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.9e-06 0.36
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 2.271e-06 0.31
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 2.324e-06 0.30
ACHB3_RAT Chrnb3 Neuronal acetylcholine receptor subunit beta-3 3.073e-06 0.30
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 5.029e-06 0.31
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 5.565e-06 0.40
CCR5_MACFA CCR5 C-C chemokine receptor type 5 5.752e-06 0.28
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 6.166e-06 0.29
AGP1_YEAST AGP1 General amino acid permease AGP1 6.605e-06 0.29
ACH4_DROME nAChRbeta2 Acetylcholine receptor subunit beta-like 2 7.294e-06 0.30
FABI_STAAR fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI 8.394e-06 0.33
MMP13_HUMAN MMP13 Collagenase 3 8.811e-06 0.32

compound_24

DGAT2_HUMAN DGAT2 Diacylglycerol O-acyltransferase 2 5.915e-119 0.40
ERG_HUMAN ERG Transcriptional regulator ERG 2.883e-29 0.31
GPBAR_MOUSE Gpbar1 G-protein coupled bile acid receptor 1 2.22e-16 0.33
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 2.22e-16 0.31
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 1.632e-14 0.32
DUS22_HUMAN DUSP22 Dual specificity protein phosphatase 22 9.387e-12 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 4.958e-11 0.35
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 2.38e-09 0.33
S10A4_HUMAN S100A4 Protein S100-A4 4.764e-09 0.32
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 7.675e-09 0.37
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 2.529e-08 0.31
ALK_HUMAN ALK ALK tyrosine kinase receptor 3.892e-08 0.33
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 2.868e-07 0.34
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 5.797e-06 0.31

compound_23

ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 2.266e-109 0.36
PANK1_HUMAN PANK1 Pantothenate kinase 1 9.993e-91 0.35
TA2R8_HUMAN TAS2R8 Taste receptor type 2 member 8 6.609e-54 0.35
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 7.727e-45 0.48
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.663e-43 0.33
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 3.03e-43 0.36
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.44e-40 0.34
PANK2_HUMAN PANK2 Pantothenate kinase 2, mitochondrial 9.279e-38 0.30
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.272e-32 0.33
DBF4A_HUMAN DBF4 Protein DBF4 homolog A 8.371e-29 0.32
KKCC2_MOUSE Camkk2 Calcium/calmodulin-dependent protein kinase kinase 2 7.318e-23 0.28
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 2.919e-22 0.32
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 2.919e-22 0.32
RYAR_DROME RYa-R RYamide receptor 2.694e-18 0.29
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 2.082e-17 0.32
PRKX_HUMAN PRKX cAMP-dependent protein kinase catalytic subunit PRKX 1.11e-16 0.33
CALRL_HUMAN CALCRL Calcitonin gene-related peptide type 1 receptor 3.331e-16 0.33
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 5.995e-15 0.40
ST17A_HUMAN STK17A Serine/threonine-protein kinase 17A 9.881e-15 0.32
KAPCA_HUMAN PRKACA cAMP-dependent protein kinase catalytic subunit alpha 1.21e-14 0.33
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 1.232e-14 0.32
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 8.127e-13 0.33
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 2.308e-12 0.32
MINK1_HUMAN MINK1 Misshapen-like kinase 1 2.42e-12 0.32
Q8MI13_BOVIN 5htr1d 5-hydroxytryptamine 1D receptor 2.721e-12 0.29
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 5.449e-12 0.31
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 5.728e-12 0.32
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 9.826e-12 0.33
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.802e-11 0.34
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.911e-11 0.33
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 3.54e-11 0.33
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 6.118e-11 0.33
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 2.119e-10 0.33
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 2.775e-10 0.32
AL1B1_HUMAN ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 2.923e-10 0.30
JUN_HUMAN JUN Transcription factor AP-1 4.597e-10 0.31
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 4.795e-10 0.33
TSSK1_HUMAN TSSK1B Testis-specific serine/threonine-protein kinase 1 5.123e-10 0.31
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1.453e-09 0.33
AL1A2_HUMAN ALDH1A2 Retinal dehydrogenase 2 1.496e-09 0.30
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 2.299e-09 0.32
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 3.933e-09 0.32
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 1.713e-08 0.35
KGP2_HUMAN PRKG2 cGMP-dependent protein kinase 2 2.014e-08 0.31
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 4.369e-08 0.31
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 5.043e-08 0.33
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 5.653e-08 0.32
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 6.739e-08 0.32
5HT1D_RAT Htr1d 5-hydroxytryptamine receptor 1D 1.578e-07 0.31
DHI1_RAT Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 5.397e-07 0.32
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 6.879e-07 0.33
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 8.92e-07 0.31
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 1.046e-06 0.34
DYRK4_HUMAN DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 1.224e-06 0.30
KGP1_HUMAN PRKG1 cGMP-dependent protein kinase 1 1.758e-06 0.31
Q5TKS5_STAAU fabI Enoyl-ACP reductase 1.942e-06 0.29
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 3.729e-06 0.33
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 3.972e-06 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 4.235e-06 0.31
BRSK1_HUMAN BRSK1 Serine/threonine-protein kinase BRSK1 4.749e-06 0.31
NAC1_HUMAN SLC8A1 Sodium/calcium exchanger 1 5.165e-06 0.33
KKCC2_HUMAN CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 6.661e-06 0.30
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 6.673e-06 0.29
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 6.772e-06 0.33

compound_28

SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 8.172e-95 0.40
SSR1_RAT Sstr1 Somatostatin receptor type 1 1.496e-48 0.38
SSR2_RAT Sstr2 Somatostatin receptor type 2 3.824e-30 0.38
P2RX3_RAT P2rx3 P2X purinoceptor 3 8.955e-21 0.32
BKRB1_MACFA BDKRB1 B1 bradykinin receptor 1.11e-15 0.32
VATB1_HUMAN ATP6V1B1 V-type proton ATPase subunit B, kidney isoform 3.922e-13 0.29
VPP1_CHICK ATP6V0A1 V-type proton ATPase 116 kDa subunit a isoform 1 3.922e-13 0.29
GP119_MOUSE Gpr119 Glucose-dependent insulinotropic receptor 5.198e-11 0.37
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 1.22e-10 0.30
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.678e-10 0.34
PANK1_HUMAN PANK1 Pantothenate kinase 1 4.951e-08 0.28
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 8.724e-07 0.31
DRD4_RAT Drd4 D(4) dopamine receptor 2.163e-06 0.33
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 3.5e-06 0.30
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 5.551e-06 0.38

compound_4

ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.748e-94 0.41
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 7.241e-63 0.40
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 1.421e-47 0.31
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 4.245e-43 0.44
OGA_RAT Oga Protein O-GlcNAcase 1.654e-40 0.33
I6X8D2_MYCTU pks13 Polyketide synthase Pks13 3.17e-38 0.30
SCAF_HHV8P ORF17 Capsid scaffolding protein 1.097e-35 0.28
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 1.742e-33 0.37
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 5.759e-33 0.31
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 9.339e-30 0.34
TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 1.116e-29 0.33
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.504e-29 0.42
ACES_MOUSE Ache Acetylcholinesterase 3.809e-28 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.325e-28 0.39
CTNB1_HUMAN CTNNB1 Catenin beta-1 2.267e-27 0.33
RCOR1_HUMAN RCOR1 REST corepressor 1 4.544e-23 0.33
PARP1_MOUSE Parp1 Poly [ADP-ribose] polymerase 1 7.676e-23 0.36
BRPF1_HUMAN BRPF1 Peregrin 1.5e-20 0.32
Q8T8E9_9TRYP galE UDP-galactose 4-epimerase 3.887e-20 0.31
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 6.151e-20 0.38
DRD1_BOVIN DRD1 D(1A) dopamine receptor 6.389e-20 0.32
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.11e-15 0.32
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.108e-15 0.31
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 5.107e-15 0.36
ACES_HUMAN ACHE Acetylcholinesterase 4.041e-14 0.39
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.417e-14 0.32
ACES_ELEEL ache Acetylcholinesterase 6.783e-14 0.38
HRH1_CAVPO HRH1 Histamine H1 receptor 9.67e-14 0.37
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 2.268e-13 0.33
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.361e-13 0.29
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 6.184e-13 0.38
CHLE_HUMAN BCHE Cholinesterase 6.567e-13 0.38
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 7.189e-13 0.35
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.105e-12 0.32
CHLE_HORSE BCHE Cholinesterase 1.458e-12 0.38
FA5_HUMAN F5 Coagulation factor V 3.305e-12 0.33
BXE_CLOBO botE Botulinum neurotoxin type E 1.196e-11 0.28
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 4.325e-11 0.37
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 5.091e-11 0.29
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 6.563e-11 0.33
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 7.502e-11 0.33
FADS1_HUMAN FADS1 Acyl-CoA (8-3)-desaturase 8.663e-11 0.31
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 8.701e-11 0.34
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.351e-10 0.33
VACHT_TETCF Vesicular acetylcholine transporter 1.923e-10 0.33
DRD3_RAT Drd3 D(3) dopamine receptor 1.953e-10 0.33
FA10_HUMAN F10 Coagulation factor X 3.679e-10 0.41
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 1.411e-09 0.30
ACES_RAT Ache Acetylcholinesterase 1.877e-09 0.33
AOX_TRYBB AOX Alternative oxidase, mitochondrial 2.988e-09 0.29
STXA_SHIDY stxA Shiga toxin subunit A 9.257e-09 0.31
CYB_PIG MT-CYB Cytochrome b 1.364e-08 0.30
DHPR_RAT Qdpr Dihydropteridine reductase 1.536e-08 0.28
DRD2_RAT Drd2 D(2) dopamine receptor 1.62e-08 0.37
TERT_HUMAN TERT Telomerase reverse transcriptase 3.095e-08 0.38
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.268e-08 0.36
DHPR_HUMAN QDPR Dihydropteridine reductase 4.589e-08 0.28
HDAC1_HUMAN HDAC1 Histone deacetylase 1 9.942e-08 0.48
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.289e-07 0.36
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.444e-07 0.33
Q8VBU5_MOUSE Pde4b Phosphodiesterase 1.467e-07 0.33
SORT_HUMAN SORT1 Sortilin 1.649e-07 0.32
PANK3_HUMAN PANK3 Pantothenate kinase 3 1.895e-07 0.29
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 2.009e-07 0.33
PD1L1_HUMAN CD274 Programmed cell death 1 ligand 1 2.362e-07 0.29
PARP2_HUMAN PARP2 Poly [ADP-ribose] polymerase 2 2.433e-07 0.33
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 2.618e-07 0.29
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 2.84e-07 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 2.878e-07 0.31
EGFR_MOUSE Egfr Epidermal growth factor receptor 3.335e-07 0.29
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 4.215e-07 0.33
Q25615_ONCVO Chitinase 4.308e-07 0.29
BRD1_HUMAN BRD1 Bromodomain-containing protein 1 4.783e-07 0.30
DRD2_MOUSE Drd2 D(2) dopamine receptor 5.162e-07 0.29
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 7.053e-07 0.38
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 7.143e-07 0.33
PRIO_SHEEP PRNP Major prion protein 8.63e-07 0.31
PDIA1_HUMAN P4HB Protein disulfide-isomerase 9.09e-07 0.31
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 1.242e-06 0.34
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.523e-06 0.33
5HT1F_HUMAN HTR1F 5-hydroxytryptamine receptor 1F 1.568e-06 0.30
DRD1_PIG DRD1 D(1A) dopamine receptor 1.592e-06 0.33
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.037e-06 0.35
PLD1_RAT Pld1 Phospholipase D1 2.983e-06 0.31
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 3.911e-06 0.29
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 3.991e-06 0.32
NCOA1_HUMAN NCOA1 Nuclear receptor coactivator 1 5.131e-06 0.30
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 5.236e-06 0.39
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 6.699e-06 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 7.95e-06 0.34
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 8.404e-06 0.28
HSF1_MOUSE Hsf1 Heat shock factor protein 1 9.266e-06 0.35

compound_14

THAS_RAT Tbxas1 Thromboxane-A synthase 6.488e-88 0.42
FABH_HAEIN fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.157e-39 0.31
THAS_HUMAN TBXAS1 Thromboxane-A synthase 2.759e-38 0.49
HMOX1_RAT Hmox1 Heme oxygenase 1 1.584e-32 0.37
FABH_STRP3 fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 3.59e-32 0.31
QPCT_HUMAN QPCT Glutaminyl-peptide cyclotransferase 1.835e-30 0.42
RXFP1_HUMAN RXFP1 Relaxin receptor 1 4.639e-28 0.33
HMOX2_RAT Hmox2 Heme oxygenase 2 2.517e-26 0.37
FABH_STAAM fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.635e-25 0.31
A2TEF2_LEIIN CYP51 Putative lanosterol 14-alpha-demethylase 1.971e-25 0.31
A4TVL0_9PROT Cereblon isoform 4 9.841e-25 0.30
CP26A_HUMAN CYP26A1 Cytochrome P450 26A1 2.243e-24 0.37
1433S_HUMAN SFN 14-3-3 protein sigma 1.348e-23 0.29
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.452e-22 0.30
FABH_ENTFA fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.374e-21 0.33
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.728e-21 0.29
Q95214_RABIT ACAT Acyl-CoA:cholesterol acyltransferase 4.261e-20 0.35
PTN1_MOUSE Ptpn1 Tyrosine-protein phosphatase non-receptor type 1 3.028e-18 0.29
STIM1_RAT Stim1 Stromal interaction molecule 1 3.045e-17 0.32
CRBN_HUMAN CRBN Protein cereblon 5.551e-16 0.30
JAK1_HUMAN JAK1 Tyrosine-protein kinase JAK1 2.442e-15 0.38
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 5.884e-15 0.33
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 6.55e-15 0.34
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.488e-14 0.34
RAGE_HUMAN AGER Advanced glycosylation end product-specific receptor 1.112e-13 0.30
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.466e-13 0.30
CP19A_HUMAN CYP19A1 Aromatase 2.538e-12 0.48
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 3.28e-12 0.38
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 3.897e-12 0.42
STIM1_HUMAN STIM1 Stromal interaction molecule 1 5.685e-12 0.32
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.343e-12 0.30
CRCM1_RAT Orai1 Calcium release-activated calcium channel protein 1 5.068e-11 0.32
CRCM1_HUMAN ORAI1 Calcium release-activated calcium channel protein 1 6.779e-11 0.32
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.289e-10 0.28
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1.513e-10 0.30
PYGL_RAT Pygl Glycogen phosphorylase, liver form 8.682e-10 0.28
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 2.66e-09 0.34
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.733e-09 0.34
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.401e-08 0.30
STXA_SHIDY stxA Shiga toxin subunit A 1.709e-08 0.30
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 1.235e-07 0.35
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.326e-07 0.32
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 1.526e-07 0.38
Q9RMI3_STAAU fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] 2.473e-07 0.31
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 2.921e-07 0.31
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 4.295e-07 0.32
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.032e-07 0.34
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 5.506e-07 0.32
G2YM83_BOTF4 Cytochrome b-c1 complex subunit Rieske, mitochondrial 6.913e-07 0.35
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 7.42e-07 0.30
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.395e-06 0.30
CCNA2_HUMAN CCNA2 Cyclin-A2 3.19e-06 0.38
HIF1A_HUMAN HIF1A Hypoxia-inducible factor 1-alpha 4.419e-06 0.36
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5.455e-06 0.30
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 8.344e-06 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.962e-06 0.32

compound_17

G3H407_CRIGR PROKR2 2.156e-76 0.41
G3HIE5_CRIGR Prokineticin receptor 1 3.382e-52 0.36
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 3.919e-27 0.40
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 1.289e-19 0.40
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 5.662e-15 0.31
Q8MHZ5_SHEEP Ghrelin/growth hormone secretagogue receptor 6.693e-12 0.31
PDE8B_HUMAN PDE8B High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 1.139e-10 0.40
NOS2_HUMAN NOS2 Nitric oxide synthase, inducible 7.398e-10 0.41
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 8.056e-10 0.36
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 3.831e-09 0.46
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 2.72e-08 0.30
BKRB1_RABIT BDKRB1 B1 bradykinin receptor 6.475e-08 0.32
PRIO_MESAU PRNP Major prion protein 6.505e-07 0.32
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 2.581e-06 0.31

compound_25

CCR3_HUMAN CCR3 C-C chemokine receptor type 3 6.944e-74 0.49
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 5.436e-50 0.46
PKR1_HUMAN PROKR1 Prokineticin receptor 1 2.462e-48 0.44
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 2.566e-42 0.46
Q5TKS5_STAAU fabI Enoyl-ACP reductase 3.996e-42 0.36
CCR5_MOUSE Ccr5 C-C chemokine receptor type 5 1.748e-38 0.35
NMT1_HUMAN NMT1 Glycylpeptide N-tetradecanoyltransferase 1 2.4e-37 0.46
CCR3_MACFA CCR3 C-C chemokine receptor type 3 2.516e-36 0.29
TRPC7_HUMAN TRPC7 Short transient receptor potential channel 7 1.343e-30 0.31
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 1.849e-28 0.30
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 3.228e-24 0.35
NMT_ASPFU nmt1 Glycylpeptide N-tetradecanoyltransferase 9.525e-24 0.33
MTLR_HUMAN MLNR Motilin receptor 3.626e-22 0.36
NR1D2_HUMAN NR1D2 Nuclear receptor subfamily 1 group D member 2 9.713e-22 0.35
TRPC6_MOUSE Trpc6 Short transient receptor potential channel 6 1.893e-21 0.31
GP183_MOUSE Gpr183 G-protein coupled receptor 183 1.246e-20 0.33
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 9.719e-20 0.38
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 7.028e-19 0.40
LIPL_HUMAN LPL Lipoprotein lipase 9.803e-19 0.30
CCL5_HUMAN CCL5 C-C motif chemokine 5 1.535e-18 0.34
ALBU_BOVIN ALB Serum albumin 6.036e-18 0.29
RYAR_DROME RYa-R RYamide receptor 9.056e-18 0.28
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 1.11e-16 0.42
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.11e-16 0.34
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 4.219e-15 0.36
HAOX2_RAT Hao2 Hydroxyacid oxidase 2 5.329e-15 0.38
MGAT3_HUMAN MGAT3 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase 1.987e-14 0.32
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 3.053e-14 0.34
MGLL_HUMAN MGLL Monoglyceride lipase 4.885e-14 0.36
PANK3_HUMAN PANK3 Pantothenate kinase 3 5.307e-14 0.29
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 7.849e-14 0.31
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 4.573e-13 0.35
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 5.475e-13 0.34
5HT1B_HUMAN HTR1B 5-hydroxytryptamine receptor 1B 9.66e-13 0.36
GP183_HUMAN GPR183 G-protein coupled receptor 183 1.131e-12 0.33
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.903e-12 0.29
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.088e-12 0.33
KCNJ1_RAT Kcnj1 ATP-sensitive inward rectifier potassium channel 1 6.089e-12 0.32
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 8.14e-12 0.34
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 8.222e-12 0.36
ACACA_RAT Acaca Acetyl-CoA carboxylase 1 1.708e-11 0.35
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.95e-11 0.31
HRH1_CAVPO HRH1 Histamine H1 receptor 2.199e-11 0.33
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 4.373e-11 0.35
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.235e-11 0.35
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.185e-10 0.32
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 3.533e-10 0.29
HRH3_CAVPO HRH3 Histamine H3 receptor 4.33e-10 0.37
AROK_HELPY aroK Shikimate kinase 1.37e-09 0.30
RYR2_HUMAN RYR2 Ryanodine receptor 2 2.843e-09 0.32
TRPC3_HUMAN TRPC3 Short transient receptor potential channel 3 3.051e-09 0.31
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 3.257e-09 0.34
AMP1_PLAFQ M1 family aminopeptidase 3.89e-09 0.33
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 4.384e-09 0.30
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 7.012e-09 0.32
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 1.159e-08 0.32
GLF_MYCTU glf UDP-galactopyranose mutase 1.295e-08 0.33
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.314e-08 0.36
ACES_MOUSE Ache Acetylcholinesterase 1.43e-08 0.37
FABI_STAA8 fabI Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI 1.98e-08 0.29
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 4.069e-08 0.34
PANK1_HUMAN PANK1 Pantothenate kinase 1 5.431e-08 0.28
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 5.635e-08 0.32
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 5.655e-08 0.32
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 5.979e-08 0.29
MEN1_HUMAN MEN1 Menin 8.706e-08 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.078e-07 0.36
BRS3_MOUSE Brs3 Bombesin receptor subtype-3 1.522e-07 0.32
LIPS_RAT Lipe Hormone-sensitive lipase 3.72e-07 0.35
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 5.791e-07 0.36
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 7.184e-07 0.32
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 8.386e-07 0.38
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 9.27e-07 0.32
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 1.078e-06 0.37
ALBU_HUMAN ALB Serum albumin 1.186e-06 0.28
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.414e-06 0.29
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 2.149e-06 0.32
THRB_BOVIN F2 Prothrombin 2.706e-06 0.35
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 3.222e-06 0.41
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.449e-06 0.36
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 3.518e-06 0.32
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 4.596e-06 0.29
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.27e-06 0.34
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 5.565e-06 0.32
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 5.942e-06 0.37
PE2R4_RAT Ptger4 Prostaglandin E2 receptor EP4 subtype 6.373e-06 0.29
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 8.177e-06 0.33
CASR_HUMAN CASR Extracellular calcium-sensing receptor 9.368e-06 0.35
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 9.872e-06 0.36

compound_33

CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.77e-62 0.46
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 3.104e-60 0.38
NPSR1_RAT Npsr1 Neuropeptide S receptor 1.457e-36 0.29
NK2R_HUMAN TACR2 Substance-K receptor 1.219e-33 0.36
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.599e-28 0.34
ADCY5_RAT Adcy5 Adenylate cyclase type 5 1.269e-25 0.38
CNR1_RAT Cnr1 Cannabinoid receptor 1 3.47e-25 0.38
ACES_MOUSE Ache Acetylcholinesterase 1.081e-24 0.38
TRPV4_HUMAN TRPV4 Transient receptor potential cation channel subfamily V member 4 4.555e-24 0.36
NEDD4_HUMAN NEDD4 E3 ubiquitin-protein ligase NEDD4 8.089e-24 0.29
GPC6A_MOUSE Gprc6a G-protein coupled receptor family C group 6 member A 1.61e-23 0.38
IMA1_HUMAN KPNA2 Importin subunit alpha-1 2.847e-23 0.29
5HT1D_MOUSE Htr1d 5-hydroxytryptamine receptor 1D 9.864e-23 0.29
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 2.342e-22 0.34
G3I1B6_CRIGR 5-hydroxytryptamine receptor 5.183e-22 0.30
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 9.474e-22 0.30
TLR9_HUMAN TLR9 Toll-like receptor 9 1.209e-21 0.36
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 4.004e-20 0.32
CBP_HUMAN CREBBP CREB-binding protein 1.11e-16 0.32
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 6.661e-16 0.31
NK2R_CAVPO TACR2 Substance-K receptor 1.554e-15 0.31
ALBU_HUMAN ALB Serum albumin 7.661e-15 0.34
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 2.52e-14 0.32
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.804e-14 0.32
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 8.937e-14 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 9.159e-14 0.31
ACOD_HUMAN SCD Acyl-CoA desaturase 1.177e-13 0.34
DPOL_HHV11 DNA polymerase catalytic subunit 3.285e-13 0.29
DPOL_VZVD DNA polymerase catalytic subunit 3.285e-13 0.29
A5A4K8_RABIT MLNR Motilin receptor 4.751e-13 0.31
OGA_RAT Oga Protein O-GlcNAcase 5.848e-13 0.28
CNR2_HUMAN CNR2 Cannabinoid receptor 2 6.182e-13 0.38
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1.107e-12 0.32
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 5.381e-12 0.35
NOS3_RAT Nos3 Nitric oxide synthase, endothelial 1.133e-11 0.28
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.443e-11 0.39
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.235e-11 0.32
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 2.503e-11 0.35
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.921e-11 0.40
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.552e-11 0.29
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 7.839e-11 0.29
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 1.068e-10 0.31
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.345e-10 0.29
HSP12_CAEEL hsp-16.2 Heat shock protein Hsp-16.2 1.936e-10 0.30
Q03732_HBV HBcAg Capsid protein 2.492e-10 0.29
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 3.678e-10 0.37
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.073e-09 0.32
LIPC_HUMAN LIPC Hepatic triacylglycerol lipase 1.425e-09 0.36
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.795e-09 0.29
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.458e-09 0.42
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.678e-09 0.32
PI2R_HUMAN PTGIR Prostacyclin receptor 2.959e-09 0.41
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 4.553e-09 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 7.068e-09 0.37
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 7.225e-09 0.35
CNR1_HUMAN CNR1 Cannabinoid receptor 1 1.049e-08 0.38
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 1.576e-08 0.30
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.759e-08 0.35
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 2.011e-08 0.32
CAN2_HUMAN CAPN2 Calpain-2 catalytic subunit 2.113e-08 0.31
GYRB_MYCSM gyrB DNA gyrase subunit B 2.597e-08 0.31
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 6.074e-08 0.36
HRH3_CAVPO HRH3 Histamine H3 receptor 1.009e-07 0.34
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.859e-07 0.30
LIPE_HUMAN LIPG Endothelial lipase 1.966e-07 0.36
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 2.188e-07 0.36
CNR2_RAT Cnr2 Cannabinoid receptor 2 2.491e-07 0.33
PK3CA_BOVIN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5.159e-07 0.31
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5.275e-07 0.32
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 6.919e-07 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 6.919e-07 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 6.919e-07 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 6.919e-07 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 6.919e-07 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 6.919e-07 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 6.919e-07 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 6.919e-07 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 6.919e-07 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 6.919e-07 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 6.919e-07 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 6.919e-07 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 6.919e-07 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 6.919e-07 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 6.919e-07 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 6.919e-07 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 6.919e-07 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 6.919e-07 0.30
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 7.266e-07 0.34
GLSK_HUMAN GLS Glutaminase kidney isoform, mitochondrial 9.863e-07 0.33
PDE8B_HUMAN PDE8B High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 1.162e-06 0.32
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.56e-06 0.29
ERCC1_HUMAN ERCC1 DNA excision repair protein ERCC-1 1.885e-06 0.34
XPF_HUMAN ERCC4 DNA repair endonuclease XPF 1.885e-06 0.34
ACES_HUMAN ACHE Acetylcholinesterase 1.98e-06 0.38
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.063e-06 0.33
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 2.423e-06 0.31
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 2.558e-06 0.29
MMP13_BOVIN MMP13 Collagenase 3 3.614e-06 0.34
ILK_HUMAN ILK Integrin-linked protein kinase 4.66e-06 0.32
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 6.318e-06 0.30
PSB10_HUMAN PSMB10 Proteasome subunit beta type-10 8.453e-06 0.31

compound_13

KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 2.694e-58 0.41
RHOA_HUMAN RHOA Transforming protein RhoA 1.596e-54 0.38
PPCE_PIG PREP Prolyl endopeptidase 1.307e-50 0.35
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 1.371e-48 0.41
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 1.052e-46 0.32
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.712e-43 0.32
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1.716e-43 0.32
LOXL2_MOUSE Loxl2 Lysyl oxidase homolog 2 1.78e-36 0.38
PXL2A_HUMAN PRXL2A Peroxiredoxin-like 2A 6.145e-36 0.28
CCR3_MACMU CCR3 C-C chemokine receptor type 3 1.522e-35 0.28
PPARD_CANLF PPARD Peroxisome proliferator-activated receptor delta 1.522e-35 0.28
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 1.875e-35 0.33
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.585e-34 0.37
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 7.953e-34 0.33
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 4.329e-29 0.33
LOXL3_HUMAN LOXL3 Lysyl oxidase homolog 3 5.403e-29 0.38
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 5.89e-27 0.38
LMBL1_HUMAN L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 2.515e-26 0.35
HRH3_HUMAN HRH3 Histamine H3 receptor 3.418e-26 0.40
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 1.697e-25 0.33
SEPR_MOUSE Fap Prolyl endopeptidase FAP 4.112e-25 0.36
LOXL2_RAT Loxl2 Lysyl oxidase homolog 2 8.319e-24 0.38
TRXR1_RAT Txnrd1 Thioredoxin reductase 1, cytoplasmic 7.051e-23 0.29
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 9.661e-22 0.38
SC6A7_HUMAN SLC6A7 Sodium-dependent proline transporter 2.907e-20 0.31
GYS1_HUMAN GYS1 Glycogen [starch] synthase, muscle 1.574e-19 0.31
PDE3B_HUMAN PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B 1.743e-19 0.35
HRH3_RAT Hrh3 Histamine H3 receptor 1.62e-18 0.36
PK3CD_MOUSE Pik3cd Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.053e-18 0.30
LYOX_HUMAN LOX Protein-lysine 6-oxidase 5.526e-18 0.34
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.289e-17 0.33
V1AR_RAT Avpr1a Vasopressin V1a receptor 1.11e-16 0.33
GRM5_HUMAN GRM5 Metabotropic glutamate receptor 5 3.331e-16 0.36
OX2R_RAT Hcrtr2 Orexin receptor type 2 4.441e-16 0.33
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 7.772e-16 0.31
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 9.992e-16 0.32
CPT2_HUMAN CPT2 Carnitine O-palmitoyltransferase 2, mitochondrial 3.22e-15 0.31
Q70GC6_9HEPC NS5B RNA-directed RNA polymerase 3.22e-15 0.31
FAS_HUMAN FASN Fatty acid synthase 4.552e-15 0.33
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.554e-14 0.31
MIP_LEGPN mip Outer membrane protein MIP 3.497e-14 0.33
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 4.752e-14 0.32
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 2.534e-13 0.37
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 2.947e-13 0.34
PDE3A_HUMAN PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase A 5.967e-13 0.35
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 7.039e-13 0.35
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 2.09e-12 0.32
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.031e-11 0.36
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.716e-11 0.33
GRM3_RAT Grm3 Metabotropic glutamate receptor 3 1.838e-11 0.35
TEC_HUMAN TEC Tyrosine-protein kinase Tec 5.282e-11 0.30
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 8.63e-11 0.31
GP183_MOUSE Gpr183 G-protein coupled receptor 183 1.037e-10 0.33
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 3.541e-10 0.36
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 5.186e-10 0.36
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 7.203e-10 0.46
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 1.33e-09 0.41
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 2.812e-09 0.34
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 3.405e-09 0.37
HRH2_CAVPO HRH2 Histamine H2 receptor 3.533e-09 0.31
DCPS_MOUSE Dcps m7GpppX diphosphatase 3.598e-09 0.29
KDM1A_HUMAN KDM1A Lysine-specific histone demethylase 1A 4.227e-09 0.33
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 5.873e-09 0.28
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 6.104e-09 0.34
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 7.77e-09 0.38
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.188e-08 0.42
OX1R_RAT Hcrtr1 Orexin receptor type 1 1.203e-08 0.33
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.507e-08 0.34
A1Z199_HUMAN BCR/ABL fusion BCR/ABL p210 fusion protein 1.704e-08 0.29
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 2.181e-08 0.32
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 4.784e-08 0.32
PDE9A_RAT Pde9a High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 1.426e-07 0.29
HRH2_HUMAN HRH2 Histamine H2 receptor 1.451e-07 0.33
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 2.012e-07 0.30
PPCE_HUMAN PREP Prolyl endopeptidase 2.677e-07 0.31
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 3.979e-07 0.29
HRH1_HUMAN HRH1 Histamine H1 receptor 4.93e-07 0.36
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 4.972e-07 0.33
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 6.048e-07 0.32
FGF2_HUMAN FGF2 Fibroblast growth factor 2 6.148e-07 0.28
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 6.415e-07 0.32
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 6.712e-07 0.36
OX2R_HUMAN HCRTR2 Orexin receptor type 2 8.3e-07 0.45
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 9.565e-07 0.33
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 1.016e-06 0.28
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 1.21e-06 0.28
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 1.886e-06 0.31
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.898e-06 0.35
KDM4A_HUMAN KDM4A Lysine-specific demethylase 4A 2.005e-06 0.32
KDM5A_HUMAN KDM5A Lysine-specific demethylase 5A 2.114e-06 0.29
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 2.147e-06 0.31
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 2.369e-06 0.29
ACHB4_HUMAN CHRNB4 Neuronal acetylcholine receptor subunit beta-4 2.577e-06 0.33
A0A059UE90_BOVIN GSK3beta Glycogen synthase kinase-3 beta splice variant X1 3.148e-06 0.31
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 3.222e-06 0.32
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 3.995e-06 0.36
HXK4_HUMAN GCK Hexokinase-4 4.422e-06 0.33
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 5.041e-06 0.33
OX1R_HUMAN HCRTR1 Orexin receptor type 1 5.535e-06 0.45
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 5.601e-06 0.31
ACHA3_HUMAN CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 6.677e-06 0.33
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 7.564e-06 0.33
BTK_HUMAN BTK Tyrosine-protein kinase BTK 7.711e-06 0.30
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 9.747e-06 0.33

compound_32

Q6L5J4_HUMAN FPRL2 FML2_HUMAN 8.238e-58 0.38
PLD1_RAT Pld1 Phospholipase D1 1.135e-54 0.34
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 2.508e-46 0.36
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 9.642e-42 0.38
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.935e-38 0.41
UTS2_MACMU UTS2 Urotensin-2 1.443e-37 0.30
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.164e-36 0.36
PLD2_HUMAN PLD2 Phospholipase D2 3.113e-36 0.34
PLD1_HUMAN PLD1 Phospholipase D1 5.013e-33 0.34
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 2.388e-32 0.41
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.164e-30 0.36
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 9.671e-30 0.38
5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 1.705e-27 0.36
OPRX_MOUSE Oprl1 Nociceptin receptor 4.345e-26 0.30
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.778e-23 0.35
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 1.014e-22 0.28
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.138e-21 0.41
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 6.854e-20 0.31
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 8.966e-19 0.36
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 2.363e-18 0.36
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 2.011e-17 0.31
DRD4_RAT Drd4 D(4) dopamine receptor 2.325e-17 0.32
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.015e-17 0.36
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.441e-16 0.36
DRD3_RAT Drd3 D(3) dopamine receptor 5.44e-15 0.35
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 3.131e-14 0.36
HRH1_CAVPO HRH1 Histamine H1 receptor 4.985e-14 0.39
DRD2_RAT Drd2 D(2) dopamine receptor 9.026e-14 0.40
OGA_RAT Oga Protein O-GlcNAcase 4.846e-13 0.28
DRD1_PIG DRD1 D(1A) dopamine receptor 6.523e-13 0.30
NAAA_RAT Naaa N-acylethanolamine-hydrolyzing acid amidase 1.143e-12 0.30
TYTR_TRYCR TPR Trypanothione reductase 4.72e-12 0.33
GNAI1_HUMAN GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 6.464e-12 0.29
GNAI3_HUMAN GNAI3 Guanine nucleotide-binding protein G(i) subunit alpha 6.464e-12 0.29
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 2.166e-11 0.31
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 6.082e-11 0.28
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 6.609e-11 0.34
GNAO_HUMAN GNAO1 Guanine nucleotide-binding protein G(o) subunit alpha 7.655e-11 0.29
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.755e-10 0.37
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.31e-10 0.44
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.411e-09 0.36
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.083e-09 0.33
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 5.878e-09 0.36
HRH1_RAT Hrh1 Histamine H1 receptor 5.912e-09 0.38
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.172e-08 0.34
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 3.7e-08 0.34
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 5.98e-08 0.28
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 7.948e-08 0.32
DRD2_BOVIN DRD2 D(2) dopamine receptor 8.967e-08 0.36
REV1_HUMAN REV1 DNA repair protein REV1 1.031e-07 0.29
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.083e-07 0.35
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.792e-07 0.39
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.425e-07 0.39
THB_HUMAN THRB Thyroid hormone receptor beta 2.614e-07 0.30
Q6PRC7_IXORI Legumain-like protease 2.761e-07 0.30
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 3.383e-07 0.39
UR2R_RAT Uts2r Urotensin-2 receptor 5.781e-07 0.34
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 7.091e-07 0.30
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 7.091e-07 0.30
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 7.091e-07 0.30
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 7.091e-07 0.30
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 7.091e-07 0.30
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 7.091e-07 0.30
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 7.091e-07 0.30
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 7.091e-07 0.30
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 7.091e-07 0.30
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 7.091e-07 0.30
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 7.091e-07 0.30
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 7.091e-07 0.30
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 7.091e-07 0.30
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 7.091e-07 0.30
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 7.091e-07 0.30
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 7.091e-07 0.30
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 7.091e-07 0.30
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 7.091e-07 0.30
OPRM_RAT Oprm1 Mu-type opioid receptor 7.609e-07 0.38
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.488e-06 0.34
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 1.582e-06 0.33
SHH_MOUSE Shh Sonic hedgehog protein 1.874e-06 0.30
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.045e-06 0.36
LIPE_HUMAN LIPG Endothelial lipase 2.483e-06 0.34
UR2R_HUMAN UTS2R Urotensin-2 receptor 3.332e-06 0.34
G3I1B6_CRIGR 5-hydroxytryptamine receptor 3.603e-06 0.32
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 3.716e-06 0.30
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.817e-06 0.39
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 4.229e-06 0.32
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 8.359e-06 0.33
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 8.707e-06 0.36
OPRX_HUMAN OPRL1 Nociceptin receptor 8.889e-06 0.35

compound_10

WDR48_HUMAN WDR48 WD repeat-containing protein 48 1.091e-57 0.33
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.212e-56 0.33
CP2A6_HUMAN CYP2A6 Cytochrome P450 2A6 1.723e-19 0.35
VHL_HUMAN VHL von Hippel-Lindau disease tumor suppressor 1.273e-11 0.29
NAMPT_MOUSE Nampt Nicotinamide phosphoribosyltransferase 7.734e-08 0.35
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 8.281e-08 0.33
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 8.648e-08 0.31
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 3.12e-07 0.33

compound_30

CP74A_ARATH CYP74A Allene oxide synthase, chloroplastic 5.798e-56 0.30
GP183_HUMAN GPR183 G-protein coupled receptor 183 3.516e-44 0.36
SL9A1_RAT Slc9a1 Sodium/hydrogen exchanger 1 6.099e-40 0.33
A1XG20_PENDI cyp51 Cytochrome P450 14alpha-demethylase 3.151e-30 0.31
GP183_MOUSE Gpr183 G-protein coupled receptor 183 5.62e-30 0.31
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 1.498e-25 0.30
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 5.214e-18 0.31
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.458e-17 0.37
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 1.11e-16 0.32
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 2.22e-16 0.30
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 5.551e-16 0.32
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.887e-15 0.37
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 3.586e-14 0.30
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 3.164e-13 0.29
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.289e-12 0.37
DRD1_PIG DRD1 D(1A) dopamine receptor 3.526e-12 0.31
Q9JKC1_RAT Bche Carboxylic ester hydrolase 6.937e-12 0.32
MGLL_MOUSE Mgll Monoglyceride lipase 3.148e-11 0.30
S13A5_HUMAN SLC13A5 Solute carrier family 13 member 5 5.176e-11 0.35
CCR8_HUMAN CCR8 C-C chemokine receptor type 8 1.004e-10 0.32
CHLE_HORSE BCHE Cholinesterase 1.79e-09 0.34
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.03e-09 0.35
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.405e-09 0.38
CYB_PIG MT-CYB Cytochrome b 6.213e-09 0.32
DRD4_HUMAN DRD4 D(4) dopamine receptor 6.327e-09 0.37
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 4.379e-08 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 4.435e-08 0.35
ADRB1_PIG ADRB1 Beta-1 adrenergic receptor 4.951e-08 0.28
ACES_RAT Ache Acetylcholinesterase 1.256e-07 0.32
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 2.022e-07 0.32
ACES_ELEEL ache Acetylcholinesterase 3.802e-07 0.34
AMYP_PIG AMY2 Pancreatic alpha-amylase 7.69e-07 0.29
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 8.969e-07 0.30
RYR2_HUMAN RYR2 Ryanodine receptor 2 4.63e-06 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 8.474e-06 0.38

compound_12

MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 8.897e-55 0.35
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.393e-13 0.33
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 1.124e-11 0.33
FAK2_MOUSE Ptk2b Protein-tyrosine kinase 2-beta 1.718e-11 0.29
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 7.424e-11 0.33
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 6.066e-10 0.32
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 2.029e-06 0.34

compound_21

DEF_MYCTU def Peptide deformylase 2.899e-46 0.31
FAS_MOUSE Fasn Fatty acid synthase 1.007e-35 0.28
F1MPW5_BOVIN PDE10A Phosphodiesterase 2.713e-30 0.32
OX1R_MOUSE Hcrtr1 Orexin receptor type 1 2.605e-27 0.34
OX2R_MOUSE Hcrtr2 Orexin receptor type 2 2.605e-27 0.34
PTGES_HUMAN PTGES Prostaglandin E synthase 4.01e-18 0.36
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 1.221e-15 0.29
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 9.21e-12 0.33
NPBW1_MOUSE Npbwr1 Neuropeptides B/W receptor type 1 1.702e-11 0.33
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 2.69e-08 0.32
HPGDS_HUMAN HPGDS Hematopoietic prostaglandin D synthase 1.149e-06 0.31
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.526e-06 0.36
DHSO_HUMAN SORD Sorbitol dehydrogenase 5.008e-06 0.36

compound_2

PAR14_HUMAN PARP14 Protein mono-ADP-ribosyltransferase PARP14 1.796e-42 0.33
PPARD_CANLF PPARD Peroxisome proliferator-activated receptor delta 6.253e-37 0.29
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 1.097e-35 0.28
DRD2_CANLF DRD2 D(2) dopamine receptor 1.71e-35 0.28
PHF8_HUMAN PHF8 Histone lysine demethylase PHF8 4.454e-35 0.35
THRB_BOVIN F2 Prothrombin 2.463e-28 0.34
FAAH2_HUMAN FAAH2 Fatty-acid amide hydrolase 2 3.516e-24 0.30
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 6.067e-22 0.31
DCMC_MOUSE Mlycd Malonyl-CoA decarboxylase, mitochondrial 1.189e-18 0.31
DGLB_MOUSE Daglb Sn1-specific diacylglycerol lipase beta 1.372e-18 0.29
TRY2_BOVIN Anionic trypsin 1.515e-18 0.31
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.22e-16 0.37
KDM2B_HUMAN KDM2B Lysine-specific demethylase 2B 7.772e-16 0.37
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.442e-15 0.37
PLMN_HUMAN PLG Plasminogen 2.708e-13 0.30
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 3.285e-13 0.29
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.258e-13 0.36
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 1.058e-12 0.29
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 4.637e-12 0.31
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 6.752e-12 0.31
PARP1_HUMAN PARP1 Poly [ADP-ribose] polymerase 1 1.892e-11 0.36
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 4.486e-11 0.36
AURKA_HUMAN AURKA Aurora kinase A 5.404e-11 0.36
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 9.585e-11 0.29
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.547e-10 0.37
PAR15_HUMAN PARP15 Protein mono-ADP-ribosyltransferase PARP15 4.084e-10 0.29
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 5.486e-10 0.30
TRY1_BOVIN Cationic trypsin 1.151e-09 0.32
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 3.172e-09 0.31
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 3.189e-09 0.29
UROK_HUMAN PLAU Urokinase-type plasminogen activator 6.343e-09 0.30
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 1.179e-08 0.33
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 1.2e-08 0.30
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 1.232e-08 0.36
KDM5B_HUMAN KDM5B Lysine-specific demethylase 5B 1.766e-08 0.37
AURKB_HUMAN AURKB Aurora kinase B 1.942e-08 0.36
CARM1_MOUSE Carm1 Histone-arginine methyltransferase CARM1 2.775e-08 0.34
THRB_HUMAN F2 Prothrombin 7.693e-08 0.34
FA10_HUMAN F10 Coagulation factor X 1.098e-07 0.33
ACMSD_HUMAN ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 1.244e-07 0.28
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.719e-07 0.29
TGFR1_MOUSE Tgfbr1 TGF-beta receptor type-1 2.824e-07 0.28
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 5.638e-07 0.34
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.65e-06 0.37
HEPS_HUMAN HPN Serine protease hepsin 3.615e-06 0.31
CHK2_HUMAN CHEK2 Serine/threonine-protein kinase Chk2 5.949e-06 0.30
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 7.153e-06 0.30
KDM4C_HUMAN KDM4C Lysine-specific demethylase 4C 9.054e-06 0.35

compound_26

ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 1.489e-39 0.34
TOPK_HUMAN PBK Lymphokine-activated killer T-cell-originated protein kinase 3.584e-37 0.33
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 6.752e-37 0.37
E2AK3_RAT Eif2ak3 Eukaryotic translation initiation factor 2-alpha kinase 3 2.333e-36 0.29
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 9.954e-36 0.45
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.887e-35 0.36
ROCK2_HUMAN ROCK2 Rho-associated protein kinase 2 7.026e-35 0.39
ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 9.547e-34 0.37
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.911e-32 0.37
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 6.523e-29 0.46
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.439e-25 0.33
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2e-22 0.39
ACHP_LYMST Acetylcholine-binding protein 4.652e-21 0.33
SEPR_MOUSE Fap Prolyl endopeptidase FAP 6.102e-20 0.36
Q1HEC0_RAT Acetyl-Coenzyme A carboxylase 2 6.009e-18 0.28
NAMPT_HUMAN NAMPT Nicotinamide phosphoribosyltransferase 3.495e-17 0.35
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.11e-16 0.44
ACES_MOUSE Ache Acetylcholinesterase 7.772e-15 0.39
G3I1B6_CRIGR 5-hydroxytryptamine receptor 8.882e-15 0.35
5HT1B_CRIGR HTR1B 5-hydroxytryptamine receptor 1B 1.321e-14 0.35
ACOD1_MOUSE Scd1 Acyl-CoA desaturase 1 5.074e-14 0.36
MIP_LEGPN mip Outer membrane protein MIP 1.365e-12 0.28
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.899e-12 0.35
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 4.567e-12 0.30
DKK1_HUMAN DKK1 Dickkopf-related protein 1 9.7e-12 0.29
Q05BA5_MOUSE Ncoa3 Nuclear receptor coactivator 1.537e-11 0.28
HRH2_CAVPO HRH2 Histamine H2 receptor 2.021e-11 0.31
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 4.489e-11 0.29
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 9.366e-11 0.29
MK03_MOUSE Mapk3 Mitogen-activated protein kinase 3 9.993e-11 0.33
ACHA6_MOUSE Chrna6 Neuronal acetylcholine receptor subunit alpha-6 1.105e-10 0.29
G3HIE5_CRIGR Prokineticin receptor 1 2.274e-10 0.36
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 2.086e-09 0.47
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 3.252e-09 0.38
PARP4_HUMAN PARP4 Protein mono-ADP-ribosyltransferase PARP4 3.598e-09 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 3.902e-09 0.36
G3H407_CRIGR PROKR2 5.492e-09 0.33
MC5R_HUMAN MC5R Melanocortin receptor 5 7.33e-09 0.33
PPCE_HUMAN PREP Prolyl endopeptidase 9.332e-09 0.33
ACOD_HUMAN SCD Acyl-CoA desaturase 9.344e-09 0.36
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.603e-08 0.30
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.894e-08 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 3.133e-08 0.36
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 4.346e-08 0.37
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 4.951e-08 0.28
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 5.39e-08 0.30
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.031e-07 0.29
PDE8A_HUMAN PDE8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 1.031e-07 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.43e-07 0.36
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 2.639e-07 0.36
MK01_MOUSE Mapk1 Mitogen-activated protein kinase 1 2.803e-07 0.33
CASP5_HUMAN CASP5 Caspase-5 5.552e-07 0.35
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.108e-06 0.29
DRD2_MOUSE Drd2 D(2) dopamine receptor 1.282e-06 0.41
STABP_HUMAN STAMBP STAM-binding protein 1.323e-06 0.34
CCR5_MACFA CCR5 C-C chemokine receptor type 5 1.366e-06 0.31
NOX5_HUMAN NOX5 NADPH oxidase 5 2.14e-06 0.29
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 2.306e-06 0.38
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.417e-06 0.40
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.836e-06 0.37
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 3.323e-06 0.41
ACES_ELEEL ache Acetylcholinesterase 4.147e-06 0.34
CASP4_HUMAN CASP4 Caspase-4 4.474e-06 0.35
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 8.789e-06 0.33

compound_9

RORG_HUMAN RORC Nuclear receptor ROR-gamma 2.54e-38 0.53
GPR6_HUMAN GPR6 G-protein coupled receptor 6 2.806e-34 0.36
Q5TKS5_STAAU fabI Enoyl-ACP reductase 2.282e-31 0.31
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.744e-29 0.30
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 6.46e-24 0.31
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.605e-22 0.34
LIPL_HUMAN LPL Lipoprotein lipase 3.72e-18 0.29
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 5.329e-15 0.34
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 6.106e-15 0.37
ATS1_HUMAN ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1 6.55e-15 0.28
DPP4_MOUSE Dpp4 Dipeptidyl peptidase 4 1.532e-14 0.31
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 2.567e-13 0.36
TKNK_HUMAN TAC3 Tachykinin-3 4.33e-12 0.29
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 6.076e-12 0.36
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.022e-10 0.32
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.461e-10 0.44
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 9.722e-10 0.42
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 1.43e-09 0.44
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.767e-09 0.34
DHPR_RAT Qdpr Dihydropteridine reductase 5.367e-09 0.30
RET4_HUMAN RBP4 Retinol-binding protein 4 7.088e-09 0.37
P2RX7_HUMAN P2RX7 P2X purinoceptor 7 1.13e-08 0.35
DHPR_HUMAN QDPR Dihydropteridine reductase 1.709e-08 0.30
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 8.503e-08 0.34
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1.604e-07 0.36
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 3.574e-07 0.35
NPY5R_RAT Npy5r Neuropeptide Y receptor type 5 5.79e-07 0.34
NK1R_HUMAN TACR1 Substance-P receptor 1.284e-06 0.36
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.62e-06 0.38
MC4R_HUMAN MC4R Melanocortin receptor 4 4.891e-06 0.35
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 9.689e-06 0.32
RORB_HUMAN RORB Nuclear receptor ROR-beta 9.878e-06 0.44

compound_31

5HT3B_MOUSE Htr3b 5-hydroxytryptamine receptor 3B 1.222e-36 0.31
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.082e-32 0.30
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 1.65e-20 0.33
KCNJ1_RAT Kcnj1 ATP-sensitive inward rectifier potassium channel 1 7.661e-15 0.32
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 9.801e-11 0.30
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 7.812e-10 0.32
Q5TKS5_STAAU fabI Enoyl-ACP reductase 3.032e-09 0.29
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 3.388e-09 0.32
HRH1_RAT Hrh1 Histamine H1 receptor 4.755e-08 0.31
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 5.714e-08 0.29
F263_HUMAN PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 3.836e-07 0.31
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 3.894e-07 0.29
PRIO_MESAU PRNP Major prion protein 2.444e-06 0.29
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 3.189e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.596e-06 0.29

compound_16

PXL2A_HUMAN PRXL2A Peroxiredoxin-like 2A 1.522e-35 0.28
KDM2A_HUMAN KDM2A Lysine-specific demethylase 2A 7.379e-25 0.36
KDM5C_HUMAN KDM5C Lysine-specific demethylase 5C 4.314e-20 0.36
TEC_HUMAN TEC Tyrosine-protein kinase Tec 1.018e-10 0.29
PPCE_MOUSE Prep Prolyl endopeptidase 1.289e-10 0.28
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.296e-09 0.30
PPCE_BOVIN PREP Prolyl endopeptidase 4.099e-09 0.28
PPCE_PIG PREP Prolyl endopeptidase 2.031e-08 0.29
M3K12_HUMAN MAP3K12 Mitogen-activated protein kinase kinase kinase 12 1.131e-07 0.33
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 1.207e-07 0.36
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 1.092e-06 0.28

compound_8

DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.058e-33 0.40
SPHK2_HUMAN SPHK2 Sphingosine kinase 2 2.764e-18 0.36
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.221e-15 0.40
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 7.661e-15 0.38
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.473e-14 0.31
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 1.457e-13 0.36
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.307e-13 0.36
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 9.85e-13 0.36
DRD1_BOVIN DRD1 D(1A) dopamine receptor 4.222e-12 0.47
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.746e-09 0.37
PDE8A_HUMAN PDE8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 1.381e-07 0.28
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 4.085e-07 0.40
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 5.068e-07 0.30
PTPRF_HUMAN PTPRF Receptor-type tyrosine-protein phosphatase F 3.766e-06 0.29

compound_29

TF7L2_HUMAN TCF7L2 Transcription factor 7-like 2 9.806e-33 0.32
CTNB1_HUMAN CTNNB1 Catenin beta-1 3.444e-30 0.32
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 9.798e-29 0.33
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 1.655e-23 0.36
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 5.537e-23 0.35
GPR39_MOUSE Gpr39 G-protein coupled receptor 39 5.922e-20 0.38
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 1.055e-19 0.34
BCR_HUMAN BCR Breakpoint cluster region protein 1.372e-18 0.29
WDR48_HUMAN WDR48 WD repeat-containing protein 48 5.547e-17 0.35
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.11e-16 0.35
GP142_HUMAN GPR142 Probable G-protein coupled receptor 142 4.885e-15 0.32
ATS4_HUMAN ADAMTS4 A disintegrin and metalloproteinase with thrombospondin motifs 4 2.72e-14 0.35
PDK4_HUMAN PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.788e-13 0.29
PDK1_HUMAN PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 2.94e-13 0.31
A6QR73_RAT Gpr39 G protein-coupled receptor 39 2.757e-12 0.30
MTLR_HUMAN MLNR Motilin receptor 2.296e-11 0.32
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 3.086e-11 0.30
GPR39_HUMAN GPR39 G-protein coupled receptor 39 5.165e-11 0.38
PDK3_HUMAN PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 8.4e-11 0.29
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.72e-10 0.31
MMP13_MOUSE Mmp13 Collagenase 3 8.516e-10 0.31
HDAC1_HUMAN HDAC1 Histone deacetylase 1 8.594e-10 0.43
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 2.3e-09 0.31
ITK_HUMAN ITK Tyrosine-protein kinase ITK/TSK 1.885e-08 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 1.974e-08 0.31
HDAC2_HUMAN HDAC2 Histone deacetylase 2 2.265e-08 0.43
ARBK2_HUMAN GRK3 Beta-adrenergic receptor kinase 2 2.404e-08 0.29
HDAC6_HUMAN HDAC6 Histone deacetylase 6 6.865e-08 0.43
HDAC3_HUMAN HDAC3 Histone deacetylase 3 8.258e-08 0.43
PANK3_HUMAN PANK3 Pantothenate kinase 3 2.077e-07 0.29
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 3.027e-07 0.34
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 5.892e-07 0.31
GRM1_HUMAN GRM1 Metabotropic glutamate receptor 1 1.049e-06 0.36
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.124e-06 0.33
KDM6B_HUMAN KDM6B Lysine-specific demethylase 6B 1.37e-06 0.31
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 2.123e-06 0.29
PETD_SPIOL petD Cytochrome b6-f complex subunit 4 2.364e-06 0.29
ARBK1_HUMAN GRK2 Beta-adrenergic receptor kinase 1 3.133e-06 0.32
STABP_HUMAN STAMBP STAM-binding protein 3.495e-06 0.31
SHH_MOUSE Shh Sonic hedgehog protein 5.027e-06 0.39

compound_35

Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 7.749e-27 0.43
NMT1_HUMAN NMT1 Glycylpeptide N-tetradecanoyltransferase 1 6.707e-22 0.35
Q4Q5S8_LEIMA NMT Glycylpeptide N-tetradecanoyltransferase 1.172e-20 0.35
TPX2_HUMAN TPX2 Targeting protein for Xklp2 1.123e-19 0.30
NMT_ASPFU nmt1 Glycylpeptide N-tetradecanoyltransferase 2.431e-14 0.32
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 1.322e-08 0.29

compound_3

ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.11e-16 0.38
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.551e-16 0.38
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 4.53e-14 0.38
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 5.331e-13 0.45
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.881e-11 0.34
MEP50_HUMAN WDR77 Methylosome protein 50 6.058e-09 0.33
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 7.487e-09 0.33
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 2.193e-08 0.45
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 3.45e-08 0.34
MA1B1_HUMAN MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 4.291e-08 0.30
ACE_MOUSE Ace Angiotensin-converting enzyme 2.729e-07 0.30
ADRM1_HUMAN ADRM1 Proteasomal ubiquitin receptor ADRM1 1.101e-06 0.29
PRS10_HUMAN PSMC6 26S proteasome regulatory subunit 10B 1.101e-06 0.29
PRS4_HUMAN PSMC1 26S proteasome regulatory subunit 4 1.101e-06 0.29
PRS6A_HUMAN PSMC3 26S proteasome regulatory subunit 6A 1.101e-06 0.29
PRS6B_HUMAN PSMC4 26S proteasome regulatory subunit 6B 1.101e-06 0.29
PRS7_HUMAN PSMC2 26S proteasome regulatory subunit 7 1.101e-06 0.29
PRS8_HUMAN PSMC5 26S proteasome regulatory subunit 8 1.101e-06 0.29
PSD11_HUMAN PSMD11 26S proteasome non-ATPase regulatory subunit 11 1.101e-06 0.29
PSD12_HUMAN PSMD12 26S proteasome non-ATPase regulatory subunit 12 1.101e-06 0.29
PSD13_HUMAN PSMD13 26S proteasome non-ATPase regulatory subunit 13 1.101e-06 0.29
PSMD1_HUMAN PSMD1 26S proteasome non-ATPase regulatory subunit 1 1.101e-06 0.29
PSMD2_HUMAN PSMD2 26S proteasome non-ATPase regulatory subunit 2 1.101e-06 0.29
PSMD3_HUMAN PSMD3 26S proteasome non-ATPase regulatory subunit 3 1.101e-06 0.29
PSMD4_HUMAN PSMD4 26S proteasome non-ATPase regulatory subunit 4 1.101e-06 0.29
PSMD6_HUMAN PSMD6 26S proteasome non-ATPase regulatory subunit 6 1.101e-06 0.29
PSMD7_HUMAN PSMD7 26S proteasome non-ATPase regulatory subunit 7 1.101e-06 0.29
PSMD8_HUMAN PSMD8 26S proteasome non-ATPase regulatory subunit 8 1.101e-06 0.29
SEM1_HUMAN SEM1 26S proteasome complex subunit SEM1 1.101e-06 0.29
CASR_HUMAN CASR Extracellular calcium-sensing receptor 9.318e-06 0.39

compound_27

O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 2.331e-15 0.30
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 5.485e-11 0.34
LPAR5_HUMAN LPAR5 Lysophosphatidic acid receptor 5 1.354e-08 0.31
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 1.069e-06 0.31
TSPO_HUMAN TSPO Translocator protein 1.247e-06 0.32

compound_18

PA2GE_MOUSE Pla2g2e Group IIE secretory phospholipase A2 5.329e-15 0.30
PA21B_MOUSE Pla2g1b Phospholipase A2 1.261e-13 0.30
PA2GE_HUMAN PLA2G2E Group IIE secretory phospholipase A2 1.261e-13 0.30
PA21B_HUMAN PLA2G1B Phospholipase A2 2.625e-13 0.32
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 5.091e-11 0.29
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 9.931e-11 0.33
A5Z252_9INFA Neuraminidase 2.419e-10 0.30
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 2.658e-10 0.28
SIR2_HUMAN SIRT2 NAD-dependent protein deacetylase sirtuin-2 5.896e-10 0.38
LYAM3_HUMAN SELP P-selectin 5.962e-10 0.31
NRAM_I77AB Neuraminidase 4.327e-09 0.30
PA2GX_MOUSE Pla2g10 Group 10 secretory phospholipase A2 6.78e-09 0.30
MEP50_HUMAN WDR77 Methylosome protein 50 1.396e-08 0.30
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.711e-08 0.30
PA2G5_MOUSE Pla2g5 Calcium-dependent phospholipase A2 1.346e-07 0.30
PA2GA_MOUSE Pla2g2a Phospholipase A2, membrane associated 5.631e-07 0.30
PDE1C_HUMAN PDE1C Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 3.229e-06 0.28
PDE1B_HUMAN PDE1B Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 4.579e-06 0.28

compound_20

CHKA_HUMAN CHKA Choline kinase alpha 1.202e-12 0.34

compound_7

CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.529e-11 0.36
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.054e-10 0.29
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 8.974e-10 0.33
P2Y12_RAT P2ry12 P2Y purinoceptor 12 1.074e-09 0.32
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 1.446e-09 0.29
TYTR_TRYBB TPR Trypanothione reductase 2.981e-09 0.33
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 1.206e-08 0.31
TRPA1_RAT Trpa1 Transient receptor potential cation channel subfamily A member 1 1.643e-07 0.30
ACLY_HUMAN ACLY ATP-citrate synthase 1.845e-07 0.34
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 5.191e-07 0.34
ETHR_MYCTU ethR HTH-type transcriptional regulator EthR 5.89e-07 0.30
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 9.396e-07 0.29
FDFT_HUMAN FDFT1 Squalene synthase 2.016e-06 0.31
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 2.095e-06 0.34
ACOX1_RAT Acox1 Peroxisomal acyl-coenzyme A oxidase 1 3.973e-06 0.32
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 8.558e-06 0.31

compound_19

PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 2.453e-11 0.34
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 6.249e-06 0.33

compound_5

PTGES_CANLF PTGES Prostaglandin E synthase 1.621e-10 0.28
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 1.85e-06 0.35

compound_34

ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.074e-08 0.36

compound_37

MEP50_HUMAN WDR77 Methylosome protein 50 9.313e-08 0.39
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.12e-07 0.39