Results of Job: search_964b1ce2-aa2d-4fbb-84d0-f40cf543147e

Query Target Key Target Name Description P-Value MaxTC

Miglustat

GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 0 1.00
B5THE3_MOUSE Sis Sucrase-isomaltase 2.244e-240 1.00
CEGT_HUMAN UGCG Ceramide glucosyltransferase 2.908e-167 1.00
Q9LGC6_ORYSJ P0504H10.9 Putative alpha-glucosidase 3.878e-145 1.00
GBA2_MOUSE Gba2 Non-lysosomal glucosylceramidase 2.9e-124 1.00
GDE_HUMAN AGL Glycogen debranching enzyme 7.118e-96 1.00
SUIS_RAT Si Sucrase-isomaltase, intestinal 1.066e-81 1.00
SUIS_HUMAN SI Sucrase-isomaltase, intestinal 1.411e-78 1.00
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 3.749e-74 1.00
LYAG_HUMAN GAA Lysosomal alpha-glucosidase 1.626e-64 1.00
LYAG_RAT Gaa Lysosomal alpha-glucosidase 3.935e-52 1.00
CEGT_MOUSE Ugcg Ceramide glucosyltransferase 3.185e-257 0.87
LYAG_MOUSE Gaa Lysosomal alpha-glucosidase 3.578e-219 0.90
GLCM_HUMAN GBA Lysosomal acid glucosylceramidase 5.582e-130 0.87
LPH_HUMAN LCT Lactase-phlorizin hydrolase 6.014e-59 0.47
P94451_GEOSE Alpha-amylase 3.087e-54 0.42
BGAL_RHIML lacZ Beta-galactosidase 4.484e-51 0.41
BGLS_RHIRD cbg-1 Beta-glucosidase 3.155e-49 0.41
BGAL_ECOLI lacZ Beta-galactosidase 7.082e-47 0.41
BGAL_HUMAN GLB1 Beta-galactosidase 9.541e-45 0.41
Q9RK76_STRCO Putative beta-hexosaminidase (Putative secreted protein) 5.459e-39 0.31
Q9GPQ4_TRYVI IAG-nucleoside hydrolase 1.061e-37 0.38
AGAL_COFAR Alpha-galactosidase 2.504e-30 0.41
GDE_RABIT AGL Glycogen debranching enzyme 5.185e-30 0.68
BGLS_AGRSA abg Beta-glucosidase 2.669e-26 0.32
LPH_RAT Lct Lactase-phlorizin hydrolase 2.958e-20 0.56
BGAL_BOVIN GLB1 Beta-galactosidase 7.346e-13 0.49
PYGL_RAT Pygl Glycogen phosphorylase, liver form 4.884e-10 0.29
FGF1_HUMAN FGF1 Fibroblast growth factor 1 1.111e-08 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.268e-07 0.29
BGAL_ECOLX lacZ Beta-galactosidase 1.237e-06 0.38
LSS_RAT Lss Lanosterol synthase 2.152e-06 0.30

Diltiazem

CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 1.982e-212 1.00
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 6.409e-36 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 2.526e-20 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 8.733e-12 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.08748 1.00
DEF_STAAM def Peptide deformylase 1.404e-67 0.39
PRIO_MOUSE Prnp Major prion protein 8.37e-41 0.32
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 6.39e-39 0.32
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 8.266e-28 0.36
KLK6_HUMAN KLK6 Kallikrein-6 7.772e-16 0.30
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 7.239e-14 0.38
CALM_BOVIN CALM Calmodulin 5.439e-12 0.32
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 9.7e-12 0.29
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 2.708e-10 0.28
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.795e-10 0.32
SNAT_SHEEP AANAT Serotonin N-acetyltransferase 5.076e-10 0.29
CALM1_HUMAN CALM1 Calmodulin-1 4.237e-09 0.32
ESR2_HUMAN ESR2 Estrogen receptor beta 7.09e-09 0.35
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 2.006e-08 0.30
CP1A1_RAT Cyp1a1 Cytochrome P450 1A1 8.502e-08 0.29
ESR1_HUMAN ESR1 Estrogen receptor 1.027e-07 0.35
TSPO_RAT Tspo Translocator protein 1.339e-06 0.66
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 3.538e-06 0.32
CCKAR_RAT Cckar Cholecystokinin receptor type A 5.33e-06 0.37

Atenolol

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.715e-187 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 8.866e-131 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 7.972e-103 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.005502 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.292e-115 0.71
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 9.763e-101 0.63
ADRB2_MOUSE Adrb2 Beta-2 adrenergic receptor 2.725e-90 0.43
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.033e-89 0.53
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 6.575e-61 0.53
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 7.684e-49 0.64
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 1.26e-38 0.41
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 4.349e-38 0.41
GPR88_MOUSE Gpr88 Probable G-protein coupled receptor 88 1.627e-37 0.30
ACACB_HUMAN ACACB Acetyl-CoA carboxylase 2 2.814e-37 0.39
DNMT1_MOUSE Dnmt1 DNA (cytosine-5)-methyltransferase 1 4.307e-37 0.36
CASR_BOVIN CASR Extracellular calcium-sensing receptor 1.215e-35 0.28
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 2.853e-31 0.33
CASR_HUMAN CASR Extracellular calcium-sensing receptor 3.865e-31 0.43
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 3.784e-30 0.41
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 8.308e-26 0.34
PAR10_HUMAN PARP10 Protein mono-ADP-ribosyltransferase PARP10 5.432e-25 0.37
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 6.581e-23 0.34
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.701e-20 0.45
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 7.653e-19 0.62
EPOR_HUMAN EPOR Erythropoietin receptor 9.056e-18 0.28
AOC3_MOUSE Aoc3 Membrane primary amine oxidase 6.661e-16 0.30
SCYD_MAGO7 SDH1 Scytalone dehydratase 2.442e-15 0.32
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.998e-15 0.33
AOFB_RAT Maob Amine oxidase [flavin-containing] B 1.443e-14 0.42
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 9.504e-14 0.30
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 1.408e-13 0.30
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.237e-12 0.30
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 1.465e-12 0.34
FDFT_RAT Fdft1 Squalene synthase 1.538e-12 0.64
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 6.135e-11 0.29
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 3.761e-10 0.30
ACRO_HUMAN ACR Acrosin 8.019e-10 0.30
PA24B_HUMAN PLA2G4B Cytosolic phospholipase A2 beta 9.918e-10 0.32
PDS_SYNE7 pds 15-cis-phytoene desaturase 1.121e-09 0.31
ACRO_PIG ACR Acrosin 2.627e-09 0.33
HISX_BRUSU hisD Histidinol dehydrogenase 5.131e-09 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 5.139e-09 0.32
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 2.351e-08 0.38
HISX_BRAOC HDH Histidinol dehydrogenase, chloroplastic 4.633e-08 0.30
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 6.381e-08 0.31
TAU_HUMAN MAPT Microtubule-associated protein tau 1.067e-07 0.30
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.106e-07 0.30
SCNNA_HUMAN SCNN1A Amiloride-sensitive sodium channel subunit alpha 1.299e-07 0.32
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 1.511e-07 0.29
CAC1I_HUMAN CACNA1I Voltage-dependent T-type calcium channel subunit alpha-1I 1.083e-06 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.777e-06 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.148e-06 0.33
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 2.914e-06 0.39
AMP1_PLAFQ M1 family aminopeptidase 6.889e-06 0.31
PCNA_HUMAN PCNA Proliferating cell nuclear antigen 8.152e-06 0.29
NMT_CANAL NMT1 Glycylpeptide N-tetradecanoyltransferase 9.134e-06 0.42

Thiethylperazine

PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.278e-154 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.887e-15 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.0002166 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 0.0002389 1.00
PRIO_MOUSE Prnp Major prion protein 3.604e-58 0.46
LYSC1_RAT Lyz1 Lysozyme C-1 1.069e-51 0.65
TYTR_TRYCR TPR Trypanothione reductase 1.087e-49 0.46
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 7.283e-41 0.46
BGLR_RAT Gusb Beta-glucuronidase 7.594e-40 0.65
EBPL_HUMAN EBPL Emopamil-binding protein-like 7.594e-40 0.65
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 9.634e-40 0.36
CALM_BOVIN CALM Calmodulin 2.833e-39 0.65
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.275e-38 0.53
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.254e-37 0.73
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.858e-36 0.36
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 2.05e-33 0.32
CALM1_HUMAN CALM1 Calmodulin-1 2.1e-29 0.65
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 5.074e-27 0.37
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.138e-24 0.36
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.175e-22 0.73
HRH1_HUMAN HRH1 Histamine H1 receptor 7.812e-22 0.73
DRD2_RAT Drd2 D(2) dopamine receptor 1.07e-20 0.65
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.79e-19 0.73
Q9IP65_HCMV US28 G protein-coupled receptor 2.502e-19 0.37
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 1.343e-18 0.31
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 1.351e-18 0.59
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.487e-18 0.73
Q39829_SOYBN Lipoxygenase 4.879e-18 0.29
DRD3_HUMAN DRD3 D(3) dopamine receptor 8.342e-18 0.73
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 4.603e-17 0.46
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.11e-16 0.65
DRD1_RAT Drd1 D(1A) dopamine receptor 2.22e-16 0.46
ERG2_YEAST ERG2 C-8 sterol isomerase 2.22e-16 0.65
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.331e-16 0.73
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.441e-16 0.53
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 5.551e-16 0.73
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.772e-16 0.32
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 4.219e-15 0.73
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 6.55e-15 0.73
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 4.452e-14 0.31
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.075e-13 0.37
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.245e-13 0.37
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.973e-13 0.73
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 4.294e-13 0.33
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 5.125e-13 0.73
HRH1_RAT Hrh1 Histamine H1 receptor 2.574e-12 0.42
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 3.768e-12 0.33
DRD1_HUMAN DRD1 D(1A) dopamine receptor 5.953e-12 0.73
DRD3_RAT Drd3 D(3) dopamine receptor 3.712e-11 0.36
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.118e-11 0.46
CHLE_HORSE BCHE Cholinesterase 7.403e-11 0.49
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 7.551e-11 0.37
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.24e-10 0.31
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 2.17e-10 0.33
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 8.038e-10 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.309e-10 0.73
DRD1_PIG DRD1 D(1A) dopamine receptor 9.49e-10 0.31
HRH2_HUMAN HRH2 Histamine H2 receptor 1.328e-09 0.53
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.598e-09 0.73
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 2.533e-09 0.29
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 5.502e-09 0.73
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.413e-08 0.73
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 1.495e-08 0.46
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 2.237e-08 0.33
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.025e-08 0.73
WDR48_HUMAN WDR48 WD repeat-containing protein 48 9.964e-08 0.65
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.214e-07 0.30
PRIO_HUMAN PRNP Major prion protein 1.277e-07 0.46
UBP1_HUMAN USP1 Ubiquitin carboxyl-terminal hydrolase 1 1.357e-07 0.65
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 9.352e-07 0.73
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 9.412e-07 0.30
NOX1_HUMAN NOX1 NADPH oxidase 1 1.341e-06 0.31
DRD2_BOVIN DRD2 D(2) dopamine receptor 2.226e-06 0.46
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.848e-06 0.73
5HT6R_RAT Htr6 5-hydroxytryptamine receptor 6 9.31e-06 0.37
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 9.46e-06 0.43

Digoxin

AT1A1_HUMAN ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 3.135e-150 1.00
AT1A3_RAT Atp1a3 Sodium/potassium-transporting ATPase subunit alpha-3 9.481e-131 1.00
AT1A2_RAT Atp1a2 Sodium/potassium-transporting ATPase subunit alpha-2 2.753e-118 1.00
AT1A1_CANLF ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1.596e-97 1.00
AT1A4_RAT Atp1a4 Sodium/potassium-transporting ATPase subunit alpha-4 2.744e-47 1.00
AT1B1_RAT Atp1b1 Sodium/potassium-transporting ATPase subunit beta-1 2.744e-47 1.00
SO1A4_RAT Slco1a4 Solute carrier organic anion transporter family member 1A4 6.524e-44 1.00
RORG_MOUSE Rorc Nuclear receptor ROR-gamma 1.722e-07 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 1.915e-07 1.00
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.064e-05 1.00
RORG_HUMAN RORC Nuclear receptor ROR-gamma 0.02798 1.00
NOTC1_MOUSE Notch1 Neurogenic locus notch homolog protein 1 1.035e-119 0.67
SO4C1_HUMAN SLCO4C1 Solute carrier organic anion transporter family member 4C1 1.975e-89 0.81
AT1B3_RAT Atp1b3 Sodium/potassium-transporting ATPase subunit beta-3 1.061e-54 0.44
AT1A1_PIG ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 4.509e-49 0.32
AT1A1_RAT Atp1a1 Sodium/potassium-transporting ATPase subunit alpha-1 4.512e-35 0.44
AT12A_HUMAN ATP12A Potassium-transporting ATPase alpha chain 2 5.324e-35 0.50
NMDE3_HUMAN GRIN2C Glutamate receptor ionotropic, NMDA 2C 1.006e-17 0.28
NOTC1_HUMAN NOTCH1 Neurogenic locus notch homolog protein 1 1.11e-15 0.38
NMDE4_HUMAN GRIN2D Glutamate receptor ionotropic, NMDA 2D 8.105e-15 0.28
KLF5_HUMAN KLF5 Krueppel-like factor 5 1.88e-06 0.44

Nisoldipine

CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.812e-150 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.413e-60 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.291e-05 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.106 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.9981 1.00
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.973e-168 0.80
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 1.923e-135 0.80
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 2.881e-77 0.38
COLA_CLOPE colA Collagenase ColA 2.904e-73 0.32
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 9.998e-63 0.80
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 5.961e-54 0.41
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 7.742e-49 0.80
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 5.692e-48 0.80
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 6.187e-41 0.80
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 8.195e-41 0.80
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 1.322e-37 0.34
AMPN_RAT Anpep Aminopeptidase N 9.406e-37 0.29
SCMU_MYCTU Secreted chorismate mutase 1.332e-36 0.29
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 4.16e-35 0.44
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 6.124e-31 0.38
MCR_HUMAN NR3C2 Mineralocorticoid receptor 8.443e-24 0.48
Q95MF8_PIG Sulfotransferase 1.211e-18 0.30
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 4.628e-18 0.42
GATA4_MOUSE Gata4 Transcription factor GATA-4 6.073e-14 0.30
NKX25_MOUSE Nkx2-5 Homeobox protein Nkx-2.5 6.073e-14 0.30
THER_BACTH npr Thermolysin 7.339e-14 0.31
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 5.421e-13 0.30
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 7.195e-13 0.41
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 1.064e-12 0.42
RORA_HUMAN RORA Nuclear receptor ROR-alpha 9.905e-12 0.30
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 1.187e-11 0.45
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 5.83e-10 0.42
MEP2_YEAST MEP2 Ammonium transporter MEP2 7.541e-10 0.29
AROQ_STRCO aroQ 3-dehydroquinate dehydratase 1.37e-09 0.30
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.37e-09 0.30
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.74e-09 0.42
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 9.23e-09 0.42
5HT7R_CAVPO HTR7 5-hydroxytryptamine receptor 7 1.181e-08 0.29
GRP3_HUMAN RASGRP3 Ras guanyl-releasing protein 3 4.581e-08 0.28
METC_ECOLI metC Cystathionine beta-lyase MetC 6.009e-08 0.31
HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 9.732e-08 0.28
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 9.817e-08 0.42
PLCG2_HUMAN PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1.031e-07 0.29
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.14e-07 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.206e-07 0.31
ILVB_ARATH ALS Acetolactate synthase, chloroplastic 5.859e-07 0.29
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 7.979e-07 0.30
Q03732_HBV HBcAg Capsid protein 1.522e-06 0.35
B4URF0_I33A0 Neuraminidase 1.878e-06 0.32
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 3.137e-06 0.80
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 6.616e-06 0.50
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 6.727e-06 0.34

Amlodipine

CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 7.827e-146 1.00
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.63e-67 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.898e-48 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.743e-33 1.00
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.937e-30 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.304e-10 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.076e-08 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 7.675e-08 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 3.019e-06 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 3.485e-05 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.5319 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.8098 1.00
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.138e-113 0.58
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 2.084e-94 0.58
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 2.829e-65 0.43
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 2.213e-57 0.36
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 2.882e-51 0.38
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 1.743e-37 0.39
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 2.77e-36 0.35
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 1.71e-32 0.43
MCR_HUMAN NR3C2 Mineralocorticoid receptor 3.019e-29 0.59
Q03732_HBV HBcAg Capsid protein 1.673e-28 0.39
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 2.362e-26 0.33
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 4.397e-22 0.43
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 1.11e-16 0.42
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 3.053e-14 0.44
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.019e-14 0.41
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 5.92e-13 0.35
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 1.319e-09 0.37
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 1.474e-09 0.31
ILVB_YEAST ILV2 Acetolactate synthase catalytic subunit, mitochondrial 1.496e-09 0.30
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 1.065e-06 0.34
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.278e-06 0.61
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 5.03e-06 0.31

Hydromorphone

OPRD_HUMAN OPRD1 Delta-type opioid receptor 6.475e-137 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 7.594e-106 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 5.71e-99 1.00
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 4.862e-140 0.61
OPRM_MOUSE Oprm1 Mu-type opioid receptor 4.513e-124 0.65
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.095e-111 0.61
OPRX_CAVPO OPRL1 Nociceptin receptor 2.476e-107 0.59
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 4.292e-101 0.65
OPRM_BOVIN OPRM1 Mu-type opioid receptor 4.634e-100 0.56
OPRD_RAT Oprd1 Delta-type opioid receptor 2.05e-94 0.65
OPRM_RAT Oprm1 Mu-type opioid receptor 1.126e-92 0.65
OPRD_MOUSE Oprd1 Delta-type opioid receptor 3.306e-85 0.69
F7HEV7_MACMU YTHDF2 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.753e-64 0.30
H9FL65_MACMU OPRK1 Kappa-type opioid receptor 1.753e-64 0.30
OPRM_MACMU OPRM1 Mu-type opioid receptor 2.545e-57 0.30
OPRK_RAT Oprk1 Kappa-type opioid receptor 5.207e-56 0.65
TLR4_MOUSE Tlr4 Toll-like receptor 4 1.44e-42 0.44
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 7.996e-20 0.29
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 2.984e-17 0.38
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 9.109e-11 0.53
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 5.659e-10 0.37
OPRX_HUMAN OPRL1 Nociceptin receptor 1.293e-08 0.38

Terfenadine

CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 7.827e-135 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.381e-34 1.00
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.601e-26 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.11e-16 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 4.441e-16 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 2.121e-14 1.00
NK2R_HUMAN TACR2 Substance-K receptor 2.343e-14 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.52e-12 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 1.053e-11 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.867e-11 1.00
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.016e-09 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 5.587e-08 1.00
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.576e-07 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 5.715e-06 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 2.071e-05 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.23e-05 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.000124 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.000155 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.0001703 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.0009137 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.001365 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.001421 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.005275 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.01181 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.01226 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.03689 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.9996 1.00
Q8WMX0_BOVIN Muscarinic receptor M1 3.084e-53 0.31
MEN1_HUMAN MEN1 Menin 1.923e-44 0.44
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.49e-41 0.41
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 4.474e-40 0.39
O19067_PIG N-methyl-D-aspartate receptor 4.694e-40 0.32
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 9.422e-39 0.31
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.819e-37 0.38
CASR_MOUSE Casr Extracellular calcium-sensing receptor 6.395e-36 0.28
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.54e-35 0.35
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 1.162e-32 0.42
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 3.855e-32 0.32
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.456e-31 0.44
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 1.676e-31 0.39
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.637e-31 0.47
EHMT2_MOUSE Ehmt2 Histone-lysine N-methyltransferase EHMT2 2.164e-27 0.34
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 8.731e-26 0.40
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 3.743e-25 0.33
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.697e-23 0.33
B6TK44_MAIZE Cycloeucalenol cycloisomerase 4.632e-23 0.30
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 4.777e-23 0.40
DRD2_MOUSE Drd2 D(2) dopamine receptor 5.495e-23 0.38
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 5.688e-23 0.40
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.445e-22 0.44
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.856e-22 0.44
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.881e-22 0.33
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 2.509e-22 0.38
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 6.417e-21 0.30
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 3.69e-20 0.40
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 9.305e-20 0.44
ABHDB_HUMAN ABHD11 Protein ABHD11 4.43e-19 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.894e-17 0.40
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.11e-16 0.35
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.219e-15 0.35
LMCPB_LEIME LMCPB Cysteine proteinase B 4.441e-15 0.29
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 1.232e-14 0.32
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.06e-14 0.45
AMYP_RAT Amy2 Pancreatic alpha-amylase 3.164e-13 0.29
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 3.773e-13 0.32
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 4.035e-13 0.36
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 4.211e-13 0.40
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 2.111e-12 0.30
CCR3_RAT Ccr3 C-C chemokine receptor type 3 1.398e-11 0.30
MGLL_MOUSE Mgll Monoglyceride lipase 2.282e-11 0.34
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.683e-11 0.36
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 2.783e-11 0.30
Q2TU57_MAIZE Sterol-8,7-isomerase 3.542e-11 0.30
Q6Q253_PIG 5-HT4R 5-hydroxytryptamine receptor 4 protein 4.393e-11 0.30
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 4.44e-11 0.34
Q63380_RAT NET Transporter 4.996e-11 0.40
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 1.127e-10 0.35
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.006e-10 0.41
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 8.799e-10 0.33
PYGL_RAT Pygl Glycogen phosphorylase, liver form 8.972e-10 0.28
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.406e-09 0.44
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.488e-09 0.31
HRH2_HUMAN HRH2 Histamine H2 receptor 5.725e-09 0.44
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 9.025e-09 0.41
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.242e-08 0.37
ERG2_YEAST ERG2 C-8 sterol isomerase 3.428e-08 0.32
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 3.663e-08 0.31
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 4.111e-08 0.38
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 4.184e-08 0.39
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 4.345e-08 0.36
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 7.445e-08 0.33
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.027e-07 0.39
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.436e-07 0.30
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.685e-07 0.44
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 2.759e-07 0.36
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.685e-07 0.33
CCR3_MOUSE Ccr3 Probable C-C chemokine receptor type 3 3.772e-07 0.30
NMDE2_RAT Grin2b Glutamate receptor ionotropic, NMDA 2B 4.222e-07 0.40
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 5.035e-07 0.32
CP19A_RAT Cyp19a1 Aromatase 2.382e-06 0.28
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.617e-06 0.32
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 3.67e-06 0.32
DRD2_RAT Drd2 D(2) dopamine receptor 4.2e-06 0.41
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 4.215e-06 0.40
DRD5_HUMAN DRD5 D(1B) dopamine receptor 8.047e-06 0.31

Tacrine

ACES_BOVIN ACHE Acetylcholinesterase 9.531e-130 1.00
CHLE_HUMAN BCHE Cholinesterase 3.457e-129 1.00
ACES_HUMAN ACHE Acetylcholinesterase 1.024e-127 1.00
ACES_ELEEL ache Acetylcholinesterase 5.8e-121 1.00
CHLE_HORSE BCHE Cholinesterase 2.361e-109 1.00
Q9JKC1_RAT Bche Carboxylic ester hydrolase 2.471e-105 1.00
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 5.529e-99 1.00
ACES_RAT Ache Acetylcholinesterase 1.522e-75 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.000184 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.317 1.00
ACES_TETCF ache Acetylcholinesterase 3.581e-83 0.70
ACHE_HUMAN CHRNE Acetylcholine receptor subunit epsilon 9.587e-69 0.55
EF2K_HUMAN EEF2K Eukaryotic elongation factor 2 kinase 3.092e-60 0.37
HNMT_RAT Hnmt Histamine N-methyltransferase 2.102e-45 0.48
TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 5.114e-29 0.36
ATP4A_PIG ATP4A Potassium-transporting ATPase alpha chain 1 7.363e-20 0.37
A4_HUMAN APP Amyloid-beta precursor protein 1.679e-19 0.54
Q9WTR4_RAT Slc6a2 Transporter 1.055e-14 0.97
PGH1_MOUSE Ptgs1 Prostaglandin G/H synthase 1 6.892e-13 0.42
ACES_MOUSE Ache Acetylcholinesterase 1.613e-12 0.59
TERA_HUMAN VCP Transitional endoplasmic reticulum ATPase 6.778e-12 0.39
HRH3_RAT Hrh3 Histamine H3 receptor 2.744e-11 0.48
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 7.655e-11 0.29
REV_HV1H2 rev Protein Rev 7.514e-10 0.39
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 1.721e-09 0.64
O97467_PLAFA ht1 Hexose transporter 1 6.228e-09 0.53
O61059_LEIME LmGT2 Glucose transporter 7.189e-09 0.53
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.145e-08 0.54
PRIO_MESAU PRNP Major prion protein 1.254e-08 0.41
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.317e-08 0.41
AOFB_HUMAN MAOB Amine oxidase [flavin-containing] B 1.326e-08 0.34
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.847e-08 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 2.073e-08 0.48
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 2.863e-08 0.37
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.986e-08 0.41
TLR8_HUMAN TLR8 Toll-like receptor 8 1.406e-07 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 3.801e-07 0.97
CHLE_MOUSE Bche Cholinesterase 3.949e-06 0.32
8ODP_HUMAN NUDT1 7,8-dihydro-8-oxoguanine triphosphatase 4.211e-06 0.38
AGTR1_CAVPO AGTR1 Type-1 angiotensin II receptor 4.915e-06 0.28
ACM2_PIG CHRM2 Muscarinic acetylcholine receptor M2 7.33e-06 0.30

Nimodipine

CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.244e-129 1.00
CAC1C_HUMAN CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 2.135e-67 1.00
TRPA1_MOUSE Trpa1 Transient receptor potential cation channel subfamily A member 1 4.13e-61 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 2.136e-08 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 1.108e-07 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 5.249e-06 1.00
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 2.18e-05 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 2.247e-05 1.00
NR1H4_HUMAN NR1H4 Bile acid receptor 0.02329 1.00
CNR1_HUMAN CNR1 Cannabinoid receptor 1 0.9986 1.00
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.779e-251 0.82
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 5.201e-194 0.82
S27A4_HUMAN SLC27A4 Long-chain fatty acid transport protein 4 1.658e-94 0.43
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 4.185e-60 0.35
S29A1_RAT Slc29a1 Equilibrative nucleoside transporter 1 6.992e-50 0.62
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.118e-49 0.57
CAC1D_HUMAN CACNA1D Voltage-dependent L-type calcium channel subunit alpha-1D 3.416e-44 0.42
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1e-39 0.69
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 1.487e-30 0.35
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 4.549e-29 0.35
GLO2_RAT Hagh Hydroxyacylglutathione hydrolase, mitochondrial 1.736e-24 0.30
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 2.623e-24 0.57
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 3.127e-23 0.39
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 1.318e-21 0.42
Q01HZ7_ORYSA OSIGBa0132E09-OSIGBa0108L24.11 Glutamine synthetase 1.375e-19 0.31
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 2.222e-18 0.57
ACRO_PIG ACR Acrosin 5.337e-18 0.32
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.022e-17 0.57
CAC1S_RAT Cacna1s Voltage-dependent L-type calcium channel subunit alpha-1S 2.481e-17 0.69
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.276e-17 0.31
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.11e-16 0.62
DDX3X_HUMAN DDX3X ATP-dependent RNA helicase DDX3X 3.331e-16 0.31
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 4.441e-16 0.44
TRPM8_RAT Trpm8 Transient receptor potential cation channel subfamily M member 8 5.551e-16 0.31
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.11e-15 0.57
GRM8_HUMAN GRM8 Metabotropic glutamate receptor 8 2.109e-15 0.34
KMO_MOUSE Kmo Kynurenine 3-monooxygenase 9.115e-14 0.34
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.149e-13 0.57
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 3.887e-13 0.42
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 4.206e-13 0.57
IF4H_HUMAN EIF4H Eukaryotic translation initiation factor 4H 1.022e-12 0.29
RORA_HUMAN RORA Nuclear receptor ROR-alpha 4.202e-12 0.33
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.309e-11 0.31
GRP3_HUMAN RASGRP3 Ras guanyl-releasing protein 3 9.307e-11 0.29
KMO_RAT Kmo Kynurenine 3-monooxygenase 9.543e-11 0.34
DYR_STAAW folA Dihydrofolate reductase 1.011e-10 0.31
KPCA_MOUSE Prkca Protein kinase C alpha type 1.968e-10 0.32
ACES_HUMAN ACHE Acetylcholinesterase 3.456e-10 0.48
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 3.655e-10 0.29
A3KMY8_BOVIN GUSB Beta-glucuronidase 3.767e-10 0.30
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 5.076e-10 0.29
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 5.366e-10 0.39
AROK_HELPY aroK Shikimate kinase 9.414e-10 0.31
TYTR_TRYBB TPR Trypanothione reductase 1.717e-09 0.34
GRM6_HUMAN GRM6 Metabotropic glutamate receptor 6 1.944e-09 0.34
COLA_CLOPE colA Collagenase ColA 2.734e-09 0.31
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.791e-09 0.29
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 4.847e-09 0.32
MRP2_HUMAN ABCC2 Canalicular multispecific organic anion transporter 1 2.389e-08 0.31
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 2.628e-08 0.44
NF2L2_HUMAN NFE2L2 Nuclear factor erythroid 2-related factor 2 3.067e-08 0.33
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 9.525e-08 0.36
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.205e-07 0.70
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 2.701e-07 0.31
SENP1_HUMAN SENP1 Sentrin-specific protease 1 3.409e-07 0.33
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 4.065e-07 0.33
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 4.603e-07 0.31
Q8ST54_TRYCR HK Phosphotransferase 5.095e-07 0.31
MIP_LEGPN mip Outer membrane protein MIP 6.257e-07 0.29
5HT1D_HUMAN HTR1D 5-hydroxytryptamine receptor 1D 7.468e-07 0.38
MDR1A_MOUSE Abcb1a ATP-dependent translocase ABCB1 1.081e-06 0.62
NORA_STAAU norA Quinolone resistance protein NorA 1.571e-06 0.31
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.737e-06 0.41
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 2.622e-06 0.62
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 2.86e-06 0.33
BGAL_ECOLX lacZ Beta-galactosidase 3.759e-06 0.35
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 4.368e-06 0.33
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.389e-06 0.30
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 5.692e-06 0.33
AGP1_YEAST AGP1 General amino acid permease AGP1 7.112e-06 0.29

Gentian_violet_cation

DNAS1_HUMAN DNASE1 Deoxyribonuclease-1 2.9e-124 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 0.0002947 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.002212 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 0.01089 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.0116 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
ANDR_RAT Ar Androgen receptor 0.01773 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.04204 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 0.06101 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.1054 1.00
NK2R_HUMAN TACR2 Substance-K receptor 0.1254 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.1968 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.3224 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 0.5554 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 0.5947 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.6272 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.8715 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.9519 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9869 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.9947 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.9968 1.00
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.9981 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.9982 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.9986 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 0.9986 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 1 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 1 1.00
ITPR1_HUMAN ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 9.662e-18 0.44
ITPR3_HUMAN ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 7.994e-15 0.44
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 2.463e-10 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.031e-07 0.29
DPOL_VACCW POL DNA polymerase 1.435e-06 0.32
HDAC1_RAT Hdac1 Histone deacetylase 1 4.596e-06 0.29
A5H660_SCHMA HDAC8 Histone deacetylase 8 9.802e-06 0.31

Mupirocin

SYI_THET8 ileS Isoleucine--tRNA ligase 2.9e-124 1.00
SYI_ECOLI ileS Isoleucine--tRNA ligase 5.121e-61 1.00
SYIC_HUMAN IARS1 Isoleucine--tRNA ligase, cytoplasmic 3.633e-40 1.00
STRP_STRP1 ska Streptokinase A 0.905 1.00
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 8.851e-09 0.28

Norepinephrine

ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 2.9e-124 1.00
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 2.9e-124 1.00
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 7.854e-53 1.00
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 9.198e-29 1.00
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 1.692e-25 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 2.123e-25 1.00
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 1.066e-19 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.632e-13 1.00
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 3.911e-12 1.00
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 6.427e-10 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.206e-08 1.00
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 3.312e-08 1.00
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.599e-05 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 0.0001617 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.0004854 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 0.0008999 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.002853 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.003049 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.01743 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 0.03968 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.906 1.00
Q06347_9HIV2 reverse transcriptase Reverse transcriptase 1.721e-49 0.39
H9TVJ1_CHISP TyR1 2.434e-47 0.59
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 5.574e-46 0.55
KYNU_RAT Kynu Kynureninase 5.239e-40 0.32
ARP19_RAT Arpp19 cAMP-regulated phosphoprotein 19 9.4e-34 0.42
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 2.519e-24 0.55
Q39829_SOYBN Lipoxygenase 9.993e-23 0.36
G3HDX1_CRIGR Alpha-1B adrenergic receptor 1.11e-16 0.32
KYNU_HUMAN KYNU Kynureninase 1.743e-14 0.32
TYRO_MOUSE Tyr Tyrosinase 5.851e-14 0.34
RNH1_HUMAN RNASEH1 Ribonuclease H1 2.802e-13 0.39
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 1.517e-12 0.58
Q2PCB5_DICLA ca Carbonic anhydrase 1.309e-11 0.31
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 1.639e-11 0.42
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 4.384e-11 0.36
TYRO_HUMAN TYR Tyrosinase 4.655e-10 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 5.219e-10 0.31
DHPR_RAT Qdpr Dihydropteridine reductase 6.557e-10 0.33
LOX15_RABIT ALOX15 Arachidonate 15-lipoxygenase 6.898e-10 0.55
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.422e-09 0.33
DHPR_HUMAN QDPR Dihydropteridine reductase 2.37e-09 0.33
COMT_PIG COMT Catechol O-methyltransferase 2.791e-09 0.29
SYUA_HUMAN SNCA Alpha-synuclein 2.827e-09 0.32
Q49PX0_9POXV N1L N1L 7.329e-09 0.31
1433G_HUMAN YWHAG 14-3-3 protein gamma 1.709e-08 0.30
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 2.143e-08 0.28
AA2BR_RAT Adora2b Adenosine receptor A2b 6.098e-08 0.42
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 7.996e-08 0.37
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 9.396e-07 0.29
Q7ZJM1_9HIV1 pol Integrase 1.354e-06 0.34
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 1.42e-06 0.36
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.845e-06 0.30
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 2.941e-06 0.28
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 5.379e-06 0.28
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 6.663e-06 0.33
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 8.279e-06 0.28

Sulpiride

DRD2_CANLF DRD2 D(2) dopamine receptor 2.9e-124 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 5.546e-58 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.586e-45 1.00
CAH1_HUMAN CA1 Carbonic anhydrase 1 2.4e-36 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.868e-29 1.00
CAH7_HUMAN CA7 Carbonic anhydrase 7 1.832e-28 1.00
CAH4_BOVIN CA4 Carbonic anhydrase 4 3.001e-28 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 7.559e-27 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.689e-22 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 3.542e-19 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.17e-18 1.00
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 7.772e-16 1.00
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 8.882e-16 1.00
A6YCJ1_9METZ Astrosclerin-3 1.221e-15 1.00
Q5TU56_ANOGA 1272966 Carbonic anhydrase 1.144e-14 1.00
CYNT_HELPY cynT Carbonic anhydrase 3.02e-14 1.00
CAN_YEAST NCE103 Carbonic anhydrase 4.785e-14 1.00
C0IX24_STYPI CA2 Carbonic anhydrase 1.731e-13 1.00
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.731e-13 1.00
B2V8E3_SULSY Carbonate dehydratase 5.523e-13 1.00
B5SU02_STYPI CA Alpha carbonic anhydrase 5.523e-13 1.00
Q31FD6_HYDCU Carbonic anhydrase, alpha family 5.523e-13 1.00
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 1.172e-08 1.00
CAN_CANAL NCE103 Carbonic anhydrase 1.769e-08 1.00
CAH15_MOUSE Ca15 Carbonic anhydrase 15 6.422e-08 1.00
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.508e-07 1.00
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 1.123e-06 1.00
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 1.261e-06 1.00
PERM_HUMAN MPO Myeloperoxidase 1.263e-05 1.00
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.188e-05 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.002309 1.00
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 2.112e-93 0.45
GLUPH_PLAF7 Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase 1.509e-60 0.39
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 1.678e-57 0.34
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.206e-53 0.38
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.129e-51 0.42
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 9.615e-51 0.38
SCMU_MYCTU Secreted chorismate mutase 8.297e-37 0.29
CASP7_HUMAN CASP7 Caspase-7 2.271e-36 0.34
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 1.822e-32 0.31
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.297e-30 0.44
DRD1_BOVIN DRD1 D(1A) dopamine receptor 4.946e-30 0.40
DRD3_RAT Drd3 D(3) dopamine receptor 4.168e-28 0.51
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 8.855e-28 0.39
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 3.636e-27 0.32
MIP_LEGPN mip Outer membrane protein MIP 1.928e-25 0.32
CAH4_HUMAN CA4 Carbonic anhydrase 4 1.22e-23 0.42
5HT6R_MOUSE Htr6 5-hydroxytryptamine receptor 6 2e-23 0.29
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 2.795e-23 0.34
CASP3_HUMAN CASP3 Caspase-3 1.845e-21 0.34
F1SH20_PIG TRHDE Uncharacterized protein 1.298e-20 0.29
MCLN3_HUMAN MCOLN3 Mucolipin-3 3.118e-19 0.35
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 5.021e-18 0.41
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.11e-16 0.62
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 1.11e-15 0.32
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 1.443e-15 0.38
ABCBB_RAT Abcb11 Bile salt export pump 1.554e-15 0.38
SEPR_MOUSE Fap Prolyl endopeptidase FAP 6.217e-15 0.34
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 7.661e-15 0.41
SPHK1_MOUSE Sphk1 Sphingosine kinase 1 8.105e-15 0.28
MMP13_RAT Mmp13 Collagenase 3 2.698e-14 0.29
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 4.496e-14 0.29
AA2BR_RAT Adora2b Adenosine receptor A2b 3.516e-13 0.31
PTPRG_HUMAN PTPRG Receptor-type tyrosine-protein phosphatase gamma 1.035e-12 0.32
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.228e-12 0.43
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.707e-12 0.38
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 3.519e-12 0.32
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 5.109e-12 0.44
OX2R_HUMAN HCRTR2 Orexin receptor type 2 5.321e-12 0.38
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.64e-11 0.32
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.582e-11 0.38
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 2.618e-11 0.30
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 4.058e-11 0.29
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 7.898e-11 0.32
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.633e-10 0.62
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 2.219e-10 0.34
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 4.059e-10 0.38
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 5.093e-10 0.31
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 5.747e-10 0.41
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 5.906e-10 0.32
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 6.991e-10 0.31
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.06e-09 0.30
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.297e-09 0.86
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 1.449e-09 0.38
CASP9_HUMAN CASP9 Caspase-9 4.868e-09 0.32
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 6.595e-09 0.36
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.974e-09 0.62
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 1.867e-08 0.30
BRPF1_HUMAN BRPF1 Peregrin 2.225e-08 0.31
MMP7_HUMAN MMP7 Matrilysin 2.789e-08 0.30
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.921e-08 0.31
DPOL_HHV6U U38 DNA polymerase catalytic subunit 3.118e-08 0.29
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 4.203e-08 0.33
CAH2_BOVIN CA2 Carbonic anhydrase 2 8.921e-08 0.29
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 1.385e-07 0.33
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.215e-07 0.34
UREA_CANEN Urease 2.818e-07 0.35
DRD1_RAT Drd1 D(1A) dopamine receptor 3.209e-07 0.59
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 3.229e-07 0.28
PDE4B_HUMAN PDE4B cAMP-specific 3',5'-cyclic phosphodiesterase 4B 3.347e-07 0.32
DLDH_MYCTU lpdC Dihydrolipoyl dehydrogenase 5.868e-07 0.32
ENV_HV1Y2 env Envelope glycoprotein gp160 7.243e-07 0.42
Q9JKC1_RAT Bche Carboxylic ester hydrolase 7.613e-07 0.31
CPT1B_RAT Cpt1b Carnitine O-palmitoyltransferase 1, muscle isoform 8.679e-07 0.29
SPHK2_HUMAN SPHK2 Sphingosine kinase 2 8.867e-07 0.30
GPR55_HUMAN GPR55 G-protein coupled receptor 55 1.302e-06 0.35
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 1.302e-06 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 1.626e-06 0.35
OPRX_CAVPO OPRL1 Nociceptin receptor 1.777e-06 0.30
PPCE_HUMAN PREP Prolyl endopeptidase 2.329e-06 0.32
Q5TKS5_STAAU fabI Enoyl-ACP reductase 2.425e-06 0.28
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.641e-06 0.29
SPHK1_HUMAN SPHK1 Sphingosine kinase 1 3.161e-06 0.30
Q9TSW7_PIG ADRA1A Alpha-1A adrenergic receptor 3.272e-06 0.28
MMP3_HUMAN MMP3 Stromelysin-1 4.785e-06 0.33
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 6.166e-06 0.29
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 7.185e-06 0.30
MMP1_HUMAN MMP1 Interstitial collagenase 7.295e-06 0.33
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 8.272e-06 0.32
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 9.866e-06 0.66

Nitisinone

HPPD_PIG HPD 4-hydroxyphenylpyruvate dioxygenase 1.244e-122 1.00
HPPD_RAT Hpd 4-hydroxyphenylpyruvate dioxygenase 9.004e-88 1.00
HPPD_HUMAN HPD 4-hydroxyphenylpyruvate dioxygenase 5.083e-11 1.00
PPOM_TOBAC PPXII Protoporphyrinogen oxidase, mitochondrial 3.502e-48 0.38
HPPD_ARATH HPD 4-hydroxyphenylpyruvate dioxygenase 7.003e-42 0.62
SC6A9_BOVIN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 7.44e-41 0.31
HPPD_DAUCA 4-hydroxyphenylpyruvate dioxygenase 5.953e-37 0.29
PAI1_HUMAN SERPINE1 Plasminogen activator inhibitor 1 2.229e-27 0.35
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 1.179e-18 0.41
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 1.232e-14 0.40
TRPV4_MOUSE Trpv4 Transient receptor potential cation channel subfamily V member 4 1.448e-13 0.40
KTHY_HUMAN DTYMK Thymidylate kinase 2.986e-13 0.29
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 6.597e-13 0.32
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 2.466e-09 0.34
Q8X6S1_ECO57 nfsA Nitroreductase A 6.78e-09 0.30
EST2_HUMAN CES2 Cocaine esterase 9.899e-09 0.37
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.383e-08 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.217e-08 0.41
Q9FYV8_MAIZE Protoporphyrinogen oxidase 1.825e-07 0.38
IF4E_HUMAN EIF4E Eukaryotic translation initiation factor 4E 3.387e-07 0.32
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 4.997e-06 0.32

Progesterone

SHBG_HUMAN SHBG Sex hormone-binding globulin 1.821e-121 1.00
ANDR_RAT Ar Androgen receptor 3.251e-89 1.00
Q690N0_BOVIN PGR Progesterone receptor 2.519e-85 1.00
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.835e-54 1.00
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 6.19e-39 1.00
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.549e-36 1.00
ANDR_MOUSE Ar Androgen receptor 1.308e-27 1.00
PRGR_RABIT PGR Progesterone receptor 2.885e-27 1.00
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.108e-25 1.00
ERG2_YEAST ERG2 C-8 sterol isomerase 6.854e-25 1.00
ANDR_HUMAN AR Androgen receptor 1.11e-16 1.00
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.11e-16 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 7.772e-16 1.00
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 2.348e-11 1.00
PRGR_HUMAN PGR Progesterone receptor 5.303e-06 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.04975 1.00
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 0.1211 1.00
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 0.5063 1.00
P2RX3_HUMAN P2RX3 P2X purinoceptor 3 0.5505 1.00
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 5.129e-251 0.64
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.735e-171 0.64
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 9.295e-161 0.78
CP19A_HUMAN CYP19A1 Aromatase 5.515e-109 0.72
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 2.105e-108 0.53
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.699e-102 0.47
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.729e-98 0.78
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 1.38e-90 0.47
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.495e-69 0.68
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 2.981e-66 0.39
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 5.112e-65 0.72
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 7.584e-56 0.36
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 1.311e-54 0.60
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 4.095e-54 0.56
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.842e-44 0.68
TAT_HV112 tat Protein Tat 4.83e-42 0.31
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 1.474e-39 0.31
DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 5.983e-39 0.32
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 7.134e-38 0.47
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.837e-37 0.44
GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 1.915e-36 0.47
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 2.943e-35 0.71
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.23e-34 0.44
SHBG_RAT Shbg Sex hormone-binding globulin 6.58e-28 0.34
GCR_MOUSE Nr3c1 Glucocorticoid receptor 8.335e-26 0.44
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 1.33e-25 0.40
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.685e-24 0.30
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.569e-23 0.36
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 2e-23 0.29
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 3.968e-23 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 4.682e-19 0.30
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 1.11e-15 0.47
PRGR_RAT Pgr Progesterone receptor 5.884e-15 0.33
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 1.533e-13 0.47
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.105e-13 0.29
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 2.597e-13 0.56
MCR_RAT Nr3c2 Mineralocorticoid receptor 4.289e-13 0.50
GPER1_HUMAN GPER1 G-protein coupled estrogen receptor 1 9.7e-12 0.29
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 2.131e-10 0.30
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 7.341e-10 0.32
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 9.352e-10 0.29
GLNA_HUMAN GLUL Glutamine synthetase 1.37e-09 0.30
ESR1_MOUSE Esr1 Estrogen receptor 3.598e-09 0.29
ESR2_MOUSE Esr2 Estrogen receptor beta 3.598e-09 0.29
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 4.086e-09 0.36
GBRB3_HUMAN GABRB3 Gamma-aminobutyric acid receptor subunit beta-3 1.452e-08 0.47
CP19A_RAT Cyp19a1 Aromatase 3.521e-08 0.57
PPO2_AGABI PPO2 Polyphenol oxidase 2 6.571e-08 0.56
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 6.884e-08 0.35
IL6_HUMAN IL6 Interleukin-6 1.106e-07 0.30
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 1.539e-07 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 1.141e-06 0.53
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 2.611e-06 0.29
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 5.923e-06 0.56

Sorafenib

VGFR2_DANRE kdr Vascular endothelial growth factor receptor 2 4.568e-115 1.00
RAF1_HUMAN RAF1 RAF proto-oncogene serine/threonine-protein kinase 6.55e-113 1.00
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.338e-94 1.00
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 3.116e-89 1.00
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 3.609e-64 1.00
CDKL3_HUMAN CDKL3 Cyclin-dependent kinase-like 3 3.647e-45 1.00
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 8.731e-44 1.00
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 2.066e-40 1.00
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 5.009e-39 1.00
MYO3B_HUMAN MYO3B Myosin-IIIb 4.574e-33 1.00
ARAF_HUMAN ARAF Serine/threonine-protein kinase A-Raf 3.664e-32 1.00
TIE2_HUMAN TEK Angiopoietin-1 receptor 1.376e-30 1.00
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.88e-30 1.00
ABL2_HUMAN ABL2 Tyrosine-protein kinase ABL2 5.07e-30 1.00
CDK15_HUMAN CDK15 Cyclin-dependent kinase 15 5.975e-29 1.00
NLK_HUMAN NLK Serine/threonine-protein kinase NLK 6.321e-29 1.00
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 6.43e-26 1.00
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 3.444e-25 1.00
CDK14_HUMAN CDK14 Cyclin-dependent kinase 14 4.197e-25 1.00
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.816e-24 1.00
CDK17_HUMAN CDK17 Cyclin-dependent kinase 17 2.468e-24 1.00
CDKL2_HUMAN CDKL2 Cyclin-dependent kinase-like 2 5.803e-23 1.00
CDPK1_PLAF7 CPK1 Calcium-dependent protein kinase 1 5.803e-23 1.00
MUSK_HUMAN MUSK Muscle, skeletal receptor tyrosine-protein kinase 5.803e-23 1.00
STK36_HUMAN STK36 Serine/threonine-protein kinase 36 2.388e-22 1.00
MYLK2_HUMAN MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 3.08e-21 1.00
MK15_HUMAN MAPK15 Mitogen-activated protein kinase 15 9.83e-21 1.00
TNK1_HUMAN TNK1 Non-receptor tyrosine-protein kinase TNK1 2.929e-20 1.00
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 4.435e-20 1.00
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 8.201e-20 1.00
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 9.745e-20 1.00
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 9.997e-20 1.00
SRPK1_HUMAN SRPK1 SRSF protein kinase 1 3.373e-19 1.00
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 5.447e-19 1.00
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 5.447e-19 1.00
TAOK2_HUMAN TAOK2 Serine/threonine-protein kinase TAO2 5.447e-19 1.00
MYLK3_HUMAN MYLK3 Myosin light chain kinase 3 9.774e-19 1.00
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.108e-18 1.00
BLK_HUMAN BLK Tyrosine-protein kinase Blk 1.667e-18 1.00
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 2.989e-18 1.00
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 3.743e-18 1.00
CTRO_HUMAN CIT Citron Rho-interacting kinase 6.58e-18 1.00
HIPK3_HUMAN HIPK3 Homeodomain-interacting protein kinase 3 6.58e-18 1.00
RIPK2_HUMAN RIPK2 Receptor-interacting serine/threonine-protein kinase 2 9.819e-18 1.00
BRAF_MOUSE Braf Serine/threonine-protein kinase B-raf 1.377e-17 1.00
M4K1_HUMAN MAP4K1 Mitogen-activated protein kinase kinase kinase kinase 1 1.396e-17 1.00
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 2.859e-17 1.00
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 2.859e-17 1.00
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.11e-16 1.00
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.11e-16 1.00
MK13_HUMAN MAPK13 Mitogen-activated protein kinase 13 1.11e-16 1.00
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 1.11e-16 1.00
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 3.331e-16 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 3.331e-16 1.00
TIE1_HUMAN TIE1 Tyrosine-protein kinase receptor Tie-1 3.331e-16 1.00
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 4.441e-16 1.00
VGFR3_HUMAN FLT4 Vascular endothelial growth factor receptor 3 8.882e-16 1.00
KCC2B_HUMAN CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta 2.331e-15 1.00
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 3.109e-15 1.00
FRK_HUMAN FRK Tyrosine-protein kinase FRK 1.754e-14 1.00
MP2K5_HUMAN MAP2K5 Dual specificity mitogen-activated protein kinase kinase 5 2.165e-14 1.00
LYN_HUMAN LYN Tyrosine-protein kinase Lyn 2.22e-14 1.00
MKNK1_HUMAN MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 3.586e-14 1.00
STK10_HUMAN STK10 Serine/threonine-protein kinase 10 5.029e-14 1.00
UFO_HUMAN AXL Tyrosine-protein kinase receptor UFO 2.325e-13 1.00
STK33_HUMAN STK33 Serine/threonine-protein kinase 33 6.558e-13 1.00
M3K19_HUMAN MAP3K19 Mitogen-activated protein kinase kinase kinase 19 9.076e-13 1.00
PLK4_HUMAN PLK4 Serine/threonine-protein kinase PLK4 1.084e-12 1.00
CDK3_HUMAN CDK3 Cyclin-dependent kinase 3 1.291e-12 1.00
DDR2_HUMAN DDR2 Discoidin domain-containing receptor 2 6.647e-12 1.00
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 8.07e-12 1.00
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 9.584e-12 1.00
MKNK2_HUMAN MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 9.65e-12 1.00
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 9.851e-12 1.00
MINK1_HUMAN MINK1 Misshapen-like kinase 1 1.729e-11 1.00
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 1.825e-11 1.00
NTRK1_HUMAN NTRK1 High affinity nerve growth factor receptor 2.359e-11 1.00
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.753e-11 1.00
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 3.086e-11 1.00
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 3.307e-11 1.00
FGR_HUMAN FGR Tyrosine-protein kinase Fgr 3.875e-11 1.00
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 3.952e-11 1.00
HIPK2_HUMAN HIPK2 Homeodomain-interacting protein kinase 2 4.761e-11 1.00
CSK_HUMAN CSK Tyrosine-protein kinase CSK 4.84e-11 1.00
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 7.503e-11 1.00
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 1.167e-10 1.00
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 1.377e-10 1.00
AURKC_HUMAN AURKC Aurora kinase C 8.2e-10 1.00
AURKB_HUMAN AURKB Aurora kinase B 1.113e-09 1.00
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.284e-09 1.00
LIMK1_HUMAN LIMK1 LIM domain kinase 1 3.571e-09 1.00
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 1.131e-08 1.00
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 1.629e-08 1.00
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 3.691e-08 1.00
MK11_HUMAN MAPK11 Mitogen-activated protein kinase 11 3.867e-08 1.00
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 5.82e-08 1.00
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 7.306e-08 1.00
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 7.388e-08 1.00
DDR1_HUMAN DDR1 Epithelial discoidin domain-containing receptor 1 1.474e-07 1.00
KS6B1_HUMAN RPS6KB1 Ribosomal protein S6 kinase beta-1 4.948e-07 1.00
TNIK_HUMAN TNIK TRAF2 and NCK-interacting protein kinase 7.863e-07 1.00
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1.11e-06 1.00
LIMK2_HUMAN LIMK2 LIM domain kinase 2 1.111e-06 1.00
AURKA_HUMAN AURKA Aurora kinase A 1.275e-06 1.00
TNI3K_HUMAN TNNI3K Serine/threonine-protein kinase TNNI3K 2.141e-06 1.00
MK12_HUMAN MAPK12 Mitogen-activated protein kinase 12 2.259e-06 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 4.273e-06 1.00
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 4.38e-06 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 8.013e-06 1.00
DYRK3_HUMAN DYRK3 Dual specificity tyrosine-phosphorylation-regulated kinase 3 1.466e-05 1.00
MERTK_HUMAN MERTK Tyrosine-protein kinase Mer 3.701e-05 1.00
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 4.563e-05 1.00
FGFR3_HUMAN FGFR3 Fibroblast growth factor receptor 3 0.0002206 1.00
INSR_HUMAN INSR Insulin receptor 0.0003609 1.00
FGFR2_HUMAN FGFR2 Fibroblast growth factor receptor 2 0.0005601 1.00
HCK_HUMAN HCK Tyrosine-protein kinase HCK 0.0006946 1.00
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 0.0008378 1.00
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 0.0008637 1.00
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 0.001005 1.00
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 0.001061 1.00
TTK_HUMAN TTK Dual specificity protein kinase TTK 0.001508 1.00
EGFR_HUMAN EGFR Epidermal growth factor receptor 0.001699 1.00
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 0.004736 1.00
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 0.007045 1.00
PAX8_HUMAN PAX8 Paired box protein Pax-8 0.01178 1.00
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 0.01239 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.01417 1.00
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 0.0243 1.00
CCNA2_HUMAN CCNA2 Cyclin-A2 0.09404 1.00
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 0.5068 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 0.6237 1.00
MC4R_HUMAN MC4R Melanocortin receptor 4 0.7865 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.9238 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.9948 1.00
GRM4_RAT Grm4 Metabotropic glutamate receptor 4 3.575e-66 0.54
BLM_HUMAN BLM Bloom syndrome protein 3.601e-49 0.48
TMPS4_HUMAN TMPRSS4 Transmembrane protease serine 4 8.109e-48 0.31
SCNAA_RAT Scn10a Sodium channel protein type 10 subunit alpha 2.579e-47 0.36
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.122e-46 0.36
P2RY1_HUMAN P2RY1 P2Y purinoceptor 1 3.811e-46 0.42
PYGL_RAT Pygl Glycogen phosphorylase, liver form 7.804e-43 0.36
H9BT73_9POAL ACCase 1.157e-39 0.31
FAA32_MYCTU fadD32 Long-chain-fatty-acid--AMP ligase FadD32 1.097e-35 0.28
NADE_BACAN nadE NH(3)-dependent NAD(+) synthetase 1.215e-35 0.28
S20A2_HUMAN SLC20A2 Sodium-dependent phosphate transporter 2 1.71e-35 0.28
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 2.102e-35 0.54
RPGF3_HUMAN RAPGEF3 Rap guanine nucleotide exchange factor 3 2.103e-35 0.38
SHH_MOUSE Shh Sonic hedgehog protein 5.407e-35 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 1.399e-34 0.37
Q25615_ONCVO Chitinase 2.689e-34 0.33
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 7.096e-33 0.39
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 6.088e-32 0.36
RPGF4_MOUSE Rapgef4 Rap guanine nucleotide exchange factor 4 9.207e-32 0.38
MYOC_HUMAN MYOC Myocilin 5.245e-27 0.33
EPHB_MYCTO Epoxide hydrolase B 2.07e-23 0.38
MCHR1_MOUSE Mchr1 Melanin-concentrating hormone receptor 1 2.581e-23 0.31
ANDR_RAT Ar Androgen receptor 2.702e-23 0.45
S20A1_HUMAN SLC20A1 Sodium-dependent phosphate transporter 1 7.318e-23 0.28
GRM5_RAT Grm5 Metabotropic glutamate receptor 5 2.207e-20 0.46
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 6.034e-20 0.71
ANDR_MOUSE Ar Androgen receptor 1.678e-19 0.39
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 1.985e-19 0.31
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.991e-19 0.36
CDKL1_HUMAN CDKL1 Cyclin-dependent kinase-like 1 4.666e-18 0.40
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 8.85e-18 0.49
TRPV1_HUMAN TRPV1 Transient receptor potential cation channel subfamily V member 1 1.011e-17 0.47
Q9SPL6_CICIN PPX1 Protoporphyrinogen oxidase 1.11e-16 0.32
Q9XQA6_POAAN psbA Photosystem II protein D1 1.11e-16 0.32
LYOX_HUMAN LOX Protein-lysine 6-oxidase 2.22e-16 0.30
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 3.331e-16 0.37
M3K6_HUMAN MAP3K6 Mitogen-activated protein kinase kinase kinase 6 4.441e-16 0.40
KTHY_MYCTU tmk Thymidylate kinase 6.661e-16 0.35
CSF1R_MOUSE Csf1r Macrophage colony-stimulating factor 1 receptor 3.442e-15 0.40
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 7.994e-15 0.36
IMDH_CRYPV Inosine-5'-monophosphate dehydrogenase 2.076e-14 0.41
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 2.442e-14 0.34
PTPA_MYCTU ptpA Probable low molecular weight protein-tyrosine-phosphatase 9.359e-14 0.41
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 7.914e-13 0.40
MET_HUMAN MET Hepatocyte growth factor receptor 9.803e-13 0.43
KCNJ6_HUMAN KCNJ6 G protein-activated inward rectifier potassium channel 2 1.017e-12 0.32
MAK_HUMAN MAK Serine/threonine-protein kinase MAK 1.593e-12 0.40
SMN_HUMAN SMN1; SMN2 Survival motor neuron protein 1.688e-12 0.30
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.953e-12 0.38
KCNJ3_HUMAN KCNJ3 G protein-activated inward rectifier potassium channel 1 4.985e-12 0.40
KAPCB_HUMAN PRKACB cAMP-dependent protein kinase catalytic subunit beta 9.784e-12 0.40
ST38L_HUMAN STK38L Serine/threonine-protein kinase 38-like 9.784e-12 0.40
ATF1_HUMAN ATF1 Cyclic AMP-dependent transcription factor ATF-1 1.168e-11 0.30
Q6FTL6_CANGA NCE103 Carbonic anhydrase 1.326e-11 0.35
C3SLB7_ECOLX glmU Bifunctional protein GlmU 1.363e-11 0.30
LOXL2_HUMAN LOXL2 Lysyl oxidase homolog 2 1.457e-11 0.30
TRPV1_RAT Trpv1 Transient receptor potential cation channel subfamily V member 1 1.995e-11 0.47
NEK9_HUMAN NEK9 Serine/threonine-protein kinase Nek9 4.559e-11 0.40
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 1.414e-10 0.40
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 1.479e-10 0.28
CDKL5_HUMAN CDKL5 Cyclin-dependent kinase-like 5 1.715e-10 0.40
KCC4_HUMAN CAMK4 Calcium/calmodulin-dependent protein kinase type IV 1.715e-10 0.40
MYO3A_HUMAN MYO3A Myosin-IIIa 1.715e-10 0.40
STK39_HUMAN STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1.715e-10 0.40
PSBA_MARPO psbA Photosystem II protein D1 3.092e-10 0.32
NEK4_HUMAN NEK4 Serine/threonine-protein kinase Nek4 5.297e-10 0.40
KCNJ5_HUMAN KCNJ5 G protein-activated inward rectifier potassium channel 4 5.432e-10 0.40
CD11A_HUMAN CDK11A Cyclin-dependent kinase 11A 5.445e-10 0.40
CDK13_HUMAN CDK13 Cyclin-dependent kinase 13 5.445e-10 0.40
MCHR2_HUMAN MCHR2 Melanin-concentrating hormone receptor 2 6.163e-10 0.29
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 1.393e-09 0.35
NEK5_HUMAN NEK5 Serine/threonine-protein kinase Nek5 1.507e-09 0.40
GLRA1_HUMAN GLRA1 Glycine receptor subunit alpha-1 3.723e-09 0.83
M3K1_HUMAN MAP3K1 Mitogen-activated protein kinase kinase kinase 1 3.726e-09 0.40
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 4.342e-09 0.71
PLK3_HUMAN PLK3 Serine/threonine-protein kinase PLK3 7.137e-09 0.40
KC1G2_HUMAN CSNK1G2 Casein kinase I isoform gamma-2 7.979e-09 0.40
CD11B_HUMAN CDK11B Cyclin-dependent kinase 11B 8.387e-09 0.40
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 8.387e-09 0.40
SGK3_HUMAN SGK3 Serine/threonine-protein kinase Sgk3 8.387e-09 0.40
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.034e-08 0.38
KS6A5_HUMAN RPS6KA5 Ribosomal protein S6 kinase alpha-5 1.476e-08 0.40
AVR2B_HUMAN ACVR2B Activin receptor type-2B 1.744e-08 0.40
CDK18_HUMAN CDK18 Cyclin-dependent kinase 18 1.744e-08 0.40
STK24_HUMAN STK24 Serine/threonine-protein kinase 24 1.744e-08 0.40
EFC4B_HUMAN CRACR2A EF-hand calcium-binding domain-containing protein 4B 2.15e-08 0.30
CAN_CANAL NCE103 Carbonic anhydrase 2.159e-08 0.35
GRM7_RAT Grm7 Metabotropic glutamate receptor 7 2.544e-08 0.32
LYAM2_HUMAN SELE E-selectin 2.849e-08 0.33
VCAM1_HUMAN VCAM1 Vascular cell adhesion protein 1 2.915e-08 0.31
NEK6_HUMAN NEK6 Serine/threonine-protein kinase Nek6 3.392e-08 0.40
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 3.392e-08 0.40
MARK2_HUMAN MARK2 Serine/threonine-protein kinase MARK2 4.287e-08 0.33
PYRD_MOUSE Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 4.46e-08 0.32
TAAR1_RAT Taar1 Trace amine-associated receptor 1 4.951e-08 0.33
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 5.796e-08 0.34
SCNAA_HUMAN SCN10A Sodium channel protein type 10 subunit alpha 5.847e-08 0.30
CILK1_HUMAN CILK1 Serine/threonine-protein kinase ICK 6.224e-08 0.40
INSRR_HUMAN INSRR Insulin receptor-related protein 6.224e-08 0.40
CNR2_MOUSE Cnr2 Cannabinoid receptor 2 7.211e-08 0.37
KC1G1_HUMAN CSNK1G1 Casein kinase I isoform gamma-1 7.733e-08 0.40
DUSTY_HUMAN DSTYK Dual serine/threonine and tyrosine protein kinase 1.086e-07 0.40
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 1.086e-07 0.40
TESK1_HUMAN TESK1 Dual specificity testis-specific protein kinase 1 1.086e-07 0.40
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 1.138e-07 0.28
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 1.457e-07 0.33
M3K13_HUMAN MAP3K13 Mitogen-activated protein kinase kinase kinase 13 1.815e-07 0.40
KS6A4_HUMAN RPS6KA4 Ribosomal protein S6 kinase alpha-4 1.912e-07 0.40
NFKB1_HUMAN NFKB1 Nuclear factor NF-kappa-B p105 subunit 2.293e-07 0.30
ANKK1_HUMAN ANKK1 Ankyrin repeat and protein kinase domain-containing protein 1 2.918e-07 0.40
STK35_HUMAN STK35 Serine/threonine-protein kinase 35 2.918e-07 0.40
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 3.161e-07 0.40
SCNAA_MOUSE Scn10a Sodium channel protein type 10 subunit alpha 3.92e-07 0.29
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 4.5e-07 0.38
STK25_HUMAN STK25 Serine/threonine-protein kinase 25 4.535e-07 0.40
PYRD_RAT Dhodh Dihydroorotate dehydrogenase (quinone), mitochondrial 5.265e-07 0.32
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 5.801e-07 0.40
KKCC1_HUMAN CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 6.837e-07 0.40
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 6.837e-07 0.40
ULK3_HUMAN ULK3 Serine/threonine-protein kinase ULK3 6.837e-07 0.40
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 8.196e-07 0.40
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.011e-06 0.31
PLCB_HUMAN AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1.148e-06 0.30
Q865E1_MACMU HRH3 Histamine receptor H3 1.431e-06 0.31
NOX1_HUMAN NOX1 NADPH oxidase 1 1.583e-06 0.31
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.816e-06 0.41
ULK1_HUMAN ULK1 Serine/threonine-protein kinase ULK1 2.015e-06 0.40
KC1D_HUMAN CSNK1D Casein kinase I isoform delta 2.406e-06 0.40
TAAR1_MOUSE Taar1 Trace amine-associated receptor 1 2.488e-06 0.33
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 2.768e-06 0.40
STK4_HUMAN STK4 Serine/threonine-protein kinase 4 2.768e-06 0.40
ULK2_HUMAN ULK2 Serine/threonine-protein kinase ULK2 2.768e-06 0.40
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 3.736e-06 0.40
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 3.736e-06 0.40
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 3.933e-06 0.30
GSK3B_RAT Gsk3b Glycogen synthase kinase-3 beta 4.399e-06 0.31
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 5.146e-06 0.37
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.188e-06 0.31
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 5.806e-06 0.32
CAH9_HUMAN CA9 Carbonic anhydrase 9 6.072e-06 0.41
SIK1_HUMAN SIK1 Serine/threonine-protein kinase SIK1 6.488e-06 0.40
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 6.969e-06 0.28
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 8.555e-06 0.36
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 8.86e-06 0.35
KMO_HUMAN KMO Kynurenine 3-monooxygenase 9.473e-06 0.31

Tolcapone

COMT_RAT Comt Catechol O-methyltransferase 1.197e-96 1.00
COMT_HUMAN COMT Catechol O-methyltransferase 8.853e-30 1.00
GPR35_HUMAN GPR35 G-protein coupled receptor 35 3.92e-18 1.00
TTHY_HUMAN TTR Transthyretin 2.22e-16 1.00
COMT_PIG COMT Catechol O-methyltransferase 2.791e-68 0.44
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 4.486e-48 0.40
COMT_MOUSE Comt Catechol O-methyltransferase 1.122e-42 0.34
KLF10_HUMAN KLF10 Krueppel-like factor 10 5.166e-42 0.33
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 2.858e-38 0.42
ACEA_CANAX ICL1 Isocitrate lyase 2.886e-36 0.38
EST1_RABIT Liver carboxylesterase 1 1.481e-29 0.43
FUT7_HUMAN FUT7 Alpha-(1,3)-fucosyltransferase 7 4.312e-28 0.32
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 2.41e-23 0.32
Q26964_TRYCR TCTS-154 Trans-sialidase 4.377e-23 0.28
Q2PCB5_DICLA ca Carbonic anhydrase 4.247e-22 0.32
ERN1_HUMAN ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 3.376e-19 0.41
FABH_MYCTU fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 6.668e-18 0.30
GLR_RAT Gcgr Glucagon receptor 9.714e-18 0.33
GSTM2_HUMAN GSTM2 Glutathione S-transferase Mu 2 1.703e-17 0.30
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 4.11e-17 0.33
Q9XQA6_POAAN psbA Photosystem II protein D1 4.11e-17 0.33
O77078_PLAFA fabH Beta-ketoacyl-acyl carrier protein synthase III 1.11e-16 0.30
TPMT_HUMAN TPMT Thiopurine S-methyltransferase 1.11e-16 0.42
DHB14_HUMAN HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 3.331e-16 0.30
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 6.661e-16 0.30
HNF4A_RAT Hnf4a Hepatocyte nuclear factor 4-alpha 2.665e-15 0.32
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.442e-15 0.33
KTHY_HUMAN DTYMK Thymidylate kinase 1.174e-13 0.30
P89582_9HIV2 pol Integrase 1.965e-13 0.29
RLGM1_TRYBB REL1 RNA-editing ligase 1, mitochondrial 2.77e-13 0.33
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 8.976e-13 0.35
VCAM1_HUMAN VCAM1 Vascular cell adhesion protein 1 1.006e-12 0.47
EST2_HUMAN CES2 Cocaine esterase 1.066e-12 0.43
HNF4A_HUMAN HNF4A Hepatocyte nuclear factor 4-alpha 1.962e-12 0.32
TYRO_MOUSE Tyr Tyrosinase 5.251e-12 0.29
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 1.063e-11 0.28
TAT_HV1H2 tat Protein Tat 1.435e-11 0.34
TRXR2_PLAF7 trxr2 Thioredoxin reductase 2 5.087e-11 0.30
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 6.179e-11 0.32
GSTP1_HUMAN GSTP1 Glutathione S-transferase P 1.431e-10 0.30
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 5.853e-10 0.38
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 6.557e-10 0.33
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 6.557e-10 0.33
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 8.726e-10 0.40
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.663e-09 0.42
Q6UCJ9_TOXGO ENR Enoyl-acyl carrier reductase 2.021e-09 0.31
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 2.37e-09 0.33
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 2.406e-09 0.29
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 2.602e-09 0.40
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6.368e-09 0.43
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 1.76e-08 0.55
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.764e-08 0.33
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.696e-07 0.32
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 2.403e-07 0.31
EST1_HUMAN CES1 Liver carboxylesterase 1 2.635e-07 0.43
PPBN_HUMAN ALPG Alkaline phosphatase, germ cell type 2.654e-07 0.29
C3SLB7_ECOLX glmU Bifunctional protein GlmU 4.603e-07 0.34
AMYP_PIG AMY2 Pancreatic alpha-amylase 6.572e-07 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.048e-06 0.39
COLA_CLOPE colA Collagenase ColA 1.374e-06 0.30
NOS3_BOVIN NOS3 Nitric oxide synthase, endothelial 1.421e-06 0.32
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.064e-06 0.31
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 3.637e-06 0.30

Indomethacin

AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.354e-81 1.00
PGH1_RAT Ptgs1 Prostaglandin G/H synthase 1 1.035e-73 1.00
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 2.138e-71 1.00
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 4.185e-65 1.00
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 4.804e-59 1.00
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.659e-58 1.00
COX2_HUMAN MT-CO2 Cytochrome c oxidase subunit 2 1.089e-50 1.00
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 8.381e-34 1.00
PGH1_HUMAN PTGS1 Prostaglandin G/H synthase 1 1.518e-33 1.00
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 2.474e-32 1.00
ALDR_BOVIN AKR1B1 Aldo-keto reductase family 1 member B1 3.138e-29 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.811e-19 1.00
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 9.774e-19 1.00
IL8_HUMAN CXCL8 Interleukin-8 1.251e-18 1.00
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 7.195e-18 1.00
PGH2_MOUSE Ptgs2 Prostaglandin G/H synthase 2 1.283e-17 1.00
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.22e-16 1.00
PGH1_BOVIN PTGS1 Prostaglandin G/H synthase 1 2.387e-14 1.00
PGH1_MOUSE Ptgs1 Prostaglandin G/H synthase 1 1.584e-12 1.00
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 1.187e-06 1.00
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.046e-05 1.00
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 0.00285 1.00
THAS_HUMAN TBXAS1 Thromboxane-A synthase 0.01078 1.00
ANDR_HUMAN AR Androgen receptor 0.03475 1.00
PD2R_MOUSE Ptgdr Prostaglandin D2 receptor 1.744e-143 0.75
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 2.265e-102 0.68
AK1C4_HUMAN AKR1C4 Aldo-keto reductase family 1 member C4 5.163e-85 0.80
GTR1_RAT Slc2a1 Solute carrier family 2, facilitated glucose transporter member 1 1.039e-78 0.63
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 7.245e-70 0.75
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 2.017e-65 0.55
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 9.609e-64 0.83
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 3.607e-57 0.39
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 2.626e-45 0.41
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 3.378e-40 0.61
Q70GC6_9HEPC NS5B RNA-directed RNA polymerase 1.054e-37 0.33
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 3.912e-37 0.41
Q16198_HUMAN EWS-Fli1 EWS-Fli1 protein 2.095e-36 0.29
KLK14_HUMAN KLK14 Kallikrein-14 8.05e-36 0.30
Q862F3_BOVIN Similar to alpha-tubulin isoform 1 4.649e-33 0.41
PI2R_HUMAN PTGIR Prostacyclin receptor 1.006e-32 0.58
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.203e-30 0.80
PE2R3_MOUSE Ptger3 Prostaglandin E2 receptor EP3 subtype 6.09e-27 0.61
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 1.452e-26 0.74
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 3.417e-26 0.61
GP183_MOUSE Gpr183 G-protein coupled receptor 183 2.986e-24 0.30
HASP_HUMAN HASPIN Serine/threonine-protein kinase haspin 7.335e-22 0.32
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 7.496e-22 0.35
KSYK_RAT Syk Tyrosine-protein kinase SYK 1.403e-21 0.32
PE2R1_RAT Ptger1 Prostaglandin E2 receptor EP1 subtype 6.928e-21 0.32
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 1.066e-20 0.34
CPT1B_HUMAN CPT1B Carnitine O-palmitoyltransferase 1, muscle isoform 4.876e-20 0.34
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.181e-18 0.32
CPT1A_HUMAN CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 2.041e-18 0.34
CLTR2_HUMAN CYSLTR2 Cysteinyl leukotriene receptor 2 4.214e-17 0.33
CPT1A_RAT Cpt1a Carnitine O-palmitoyltransferase 1, liver isoform 1.11e-16 0.34
CYSP_PLAFA Trophozoite cysteine proteinase 1.11e-16 0.29
FABPI_HUMAN FABP2 Fatty acid-binding protein, intestinal 1.11e-16 0.32
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 3.331e-16 0.41
NORA_STAAU norA Quinolone resistance protein NorA 1.998e-15 0.32
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 3.142e-14 0.46
LOX5_RAT Alox5 Arachidonate 5-lipoxygenase 3.365e-13 0.82
EST1_RABIT Liver carboxylesterase 1 4.3e-13 0.31
EDNRA_RAT Ednra Endothelin-1 receptor 5.336e-13 0.36
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.038e-12 0.40
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.16e-12 0.31
KLK5_HUMAN KLK5 Kallikrein-5 5.393e-12 0.30
DYR_BOVIN DHFR Dihydrofolate reductase 1.416e-11 0.32
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 2.324e-11 0.36
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 2.501e-11 0.30
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 4.024e-11 0.31
PPARA_CANLF PPARA Peroxisome proliferator-activated receptor alpha 6.128e-11 0.32
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 1.07e-10 0.30
EDNRB_PIG EDNRB Endothelin receptor type B 1.751e-10 0.31
PRTN3_HUMAN PRTN3 Myeloblastin 1.779e-10 0.32
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 3.32e-10 0.51
ACRO_HUMAN ACR Acrosin 4.265e-10 0.32
GRM3_HUMAN GRM3 Metabotropic glutamate receptor 3 4.872e-10 0.31
GP183_HUMAN GPR183 G-protein coupled receptor 183 5.387e-10 0.30
XDH_BOVIN XDH Xanthine dehydrogenase/oxidase 8.923e-10 0.34
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 4.315e-09 0.67
MURB_ECOLI murB UDP-N-acetylenolpyruvoylglucosamine reductase 5.32e-09 0.34
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 5.47e-09 0.33
DPOL_HHV6U U38 DNA polymerase catalytic subunit 5.818e-09 0.32
CLTR1_HUMAN CYSLTR1 Cysteinyl leukotriene receptor 1 6.187e-09 0.33
KCNJ2_MOUSE Kcnj2 Inward rectifier potassium channel 2 6.78e-09 0.30
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 9.005e-09 0.31
NQO2_HUMAN NQO2 Ribosyldihydronicotinamide dehydrogenase [quinone] 1.902e-08 0.38
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 2.002e-08 0.30
BAZ2A_HUMAN BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 2.355e-08 0.30
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.472e-08 0.44
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 3.049e-08 0.33
PANC_MYCTU panC Pantothenate synthetase 3.73e-08 0.31
A5H660_SCHMA HDAC8 Histone deacetylase 8 4.051e-08 0.30
SPRE_HUMAN SPR Sepiapterin reductase 5.037e-08 0.30
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 5.192e-08 0.28
SSR5_HUMAN SSTR5 Somatostatin receptor type 5 5.544e-08 0.33
P96830_MYCTO TYR_PHOSPHATASE_2 domain-containing protein 7.546e-08 0.41
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 1.032e-07 0.41
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 1.141e-07 0.41
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1.264e-07 0.30
THA_HUMAN THRA Thyroid hormone receptor alpha 1.268e-07 0.33
CPT2_RAT Cpt2 Carnitine O-palmitoyltransferase 2, mitochondrial 1.269e-07 0.32
Q38C41_TRYB2 Phosphotransferase 1.498e-07 0.34
POLG_WNV Genome polyprotein 1.976e-07 0.32
LTC4S_HUMAN LTC4S Leukotriene C4 synthase 2.036e-07 0.30
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.739e-07 0.34
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 3.029e-07 0.31
GLR_HUMAN GCGR Glucagon receptor 3.033e-07 0.35
EIS_MYCTU eis N-acetyltransferase Eis 3.732e-07 0.32
FADS1_RAT Fads1 Acyl-CoA (8-3)-desaturase 3.975e-07 0.37
GRIK2_HUMAN GRIK2 Glutamate receptor ionotropic, kainate 2 3.981e-07 0.33
THB_RAT Thrb Thyroid hormone receptor beta 5.401e-07 0.30
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.412e-07 0.65
ELNE_HUMAN ELANE Neutrophil elastase 9.007e-07 0.46
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 1.138e-06 0.33
EST2_HUMAN CES2 Cocaine esterase 1.181e-06 0.31
OXER1_HUMAN OXER1 Oxoeicosanoid receptor 1 1.961e-06 0.29
HDAC6_HUMAN HDAC6 Histone deacetylase 6 2.298e-06 0.65
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 2.551e-06 0.32
MMP16_HUMAN MMP16 Matrix metalloproteinase-16 2.99e-06 0.29
CNR2_HUMAN CNR2 Cannabinoid receptor 2 3.154e-06 0.82
THB_HUMAN THRB Thyroid hormone receptor beta 3.215e-06 0.33
AOFB_BOVIN MAOB Amine oxidase [flavin-containing] B 3.591e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 3.933e-06 0.30
Q7ZJM1_9HIV1 pol Integrase 4.041e-06 0.35
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 4.222e-06 0.36
PRIO_HUMAN PRNP Major prion protein 4.78e-06 0.32
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 7.494e-06 0.30
SDF1_HUMAN CXCL12 Stromal cell-derived factor 1 8.558e-06 0.28
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 9.064e-06 0.32
ELAV1_HUMAN ELAVL1 ELAV-like protein 1 9.133e-06 0.29

Loxapine

HRH4_HUMAN HRH4 Histamine H4 receptor 1.959e-78 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 6.429e-28 1.00
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.857e-25 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.898e-24 1.00
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.411e-24 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 3.491e-23 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 6.661e-19 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 4.751e-08 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.842e-08 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 6.578e-08 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.413e-05 1.00
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 0.000243 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.379e-71 0.74
HRH4_RAT Hrh4 Histamine H4 receptor 6.979e-48 0.35
DRD1_RAT Drd1 D(1A) dopamine receptor 3.831e-45 0.73
PRIO_MOUSE Prnp Major prion protein 7.62e-36 0.28
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.982e-18 0.35
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 4.162e-18 0.41
Q91ZY3_CAVPO HRH4 Histamine H4 receptor 6.785e-18 0.28
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 1.887e-15 0.33
DRD2_BOVIN DRD2 D(2) dopamine receptor 9.437e-15 0.43
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.343e-14 0.45
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 3.553e-14 0.33
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 7.327e-14 0.74
TYTR_TRYBB TPR Trypanothione reductase 1.06e-13 0.34
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 1.883e-13 0.33
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 3.617e-13 0.33
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 4.081e-11 0.38
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 9.793e-11 0.33
CALM_BOVIN CALM Calmodulin 1.336e-10 0.28
HRH1_HUMAN HRH1 Histamine H1 receptor 3.486e-10 0.80
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 1.885e-09 0.33
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.226e-09 0.28
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.106e-08 0.33
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 2.182e-08 0.36
OPRX_RAT Oprl1 Nociceptin receptor 2.649e-08 0.33
HRH4_MOUSE Hrh4 Histamine H4 receptor 2.775e-08 0.32
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 3.665e-08 0.33
CALM1_HUMAN CALM1 Calmodulin-1 4.589e-08 0.28
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 4.664e-08 0.36
DRD4_RAT Drd4 D(4) dopamine receptor 5.826e-08 0.40
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.729e-07 0.74
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.344e-07 0.74
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 7.453e-07 0.32
AHR_HUMAN AHR Aryl hydrocarbon receptor 8.553e-07 0.33
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.154e-06 0.33
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 2.665e-06 0.74
DRD3_RAT Drd3 D(3) dopamine receptor 3.499e-06 0.42
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.749e-06 0.32
HRH2_HUMAN HRH2 Histamine H2 receptor 5.528e-06 0.80
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 6.038e-06 0.74
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 6.433e-06 0.29

Zoledronic_acid

ISPA_ECOLI ispA Farnesyl diphosphate synthase 1.063e-74 1.00
FPPS_HUMAN FDPS Farnesyl pyrophosphate synthase 1.065e-66 1.00
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 8.511e-46 1.00
GGPPS_YEAST BTS1 Geranylgeranyl pyrophosphate synthase 1.331e-42 1.00
BT3A1_HUMAN BTN3A1 Butyrophilin subfamily 3 member A1 2.191e-35 1.00
GGPPS_HUMAN GGPS1 Geranylgeranyl pyrophosphate synthase 8.644e-20 1.00
CAH14_HUMAN CA14 Carbonic anhydrase 14 0.02729 1.00
CAH12_HUMAN CA12 Carbonic anhydrase 12 0.7093 1.00
CAH9_HUMAN CA9 Carbonic anhydrase 9 0.8695 1.00
MMP2_HUMAN MMP2 72 kDa type IV collagenase 0.9472 1.00
CAH2_HUMAN CA2 Carbonic anhydrase 2 0.9984 1.00
CPXA_PSEPU camC Camphor 5-monooxygenase 1.163e-56 0.40
THAS_HUMAN TBXAS1 Thromboxane-A synthase 6.461e-48 0.44
THAS_RAT Tbxas1 Thromboxane-A synthase 2.403e-44 0.35
HMOX1_RAT Hmox1 Heme oxygenase 1 3.043e-44 0.34
Q8ST54_TRYCR HK Phosphotransferase 1.203e-23 0.44
HMOX2_RAT Hmox2 Heme oxygenase 2 2.372e-21 0.33
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 6.389e-19 0.37
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 1.11e-16 0.42
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 4.071e-11 0.42
Q8WS26_TRYCR Farnesyl diphosphate synthase 2.583e-10 0.37
Q8MTZ4_9TRYP PPase1 Vacuolar-type proton translocating pyrophosphatase 1 2.06e-07 0.32
PLAP_HUMAN PLAA Phospholipase A-2-activating protein 3.409e-07 0.33
CP19A_HUMAN CYP19A1 Aromatase 4.124e-07 0.35
CP51A_HUMAN CYP51A1 Lanosterol 14-alpha demethylase 3.052e-06 0.31
C11B1_RAT Cyp11b1 Cytochrome P450 11B1, mitochondrial 7.884e-06 0.31

Megestrol_acetate

Q690N0_BOVIN PGR Progesterone receptor 1.193e-72 1.00
ANDR_RAT Ar Androgen receptor 1.927e-22 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 9.155e-11 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.8822 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.675e-56 0.41
SHBG_HUMAN SHBG Sex hormone-binding globulin 1.433e-40 0.59
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 8.463e-38 0.33
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.223e-37 0.31
CP19A_HUMAN CYP19A1 Aromatase 7.216e-29 0.58
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.039e-27 0.32
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.056e-23 0.33
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.082e-22 0.34
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.43e-20 0.33
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 8.29e-19 0.30
PRGR_RAT Pgr Progesterone receptor 9.504e-14 0.30
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.951e-13 0.38
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.827e-13 0.34
ANDR_MOUSE Ar Androgen receptor 5.388e-13 0.59
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 9.303e-13 0.34
ABCBB_RAT Abcb11 Bile salt export pump 1.794e-12 0.30
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 6.433e-11 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 7.356e-11 0.34
PRGR_RABIT PGR Progesterone receptor 8.035e-10 0.34
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 3.031e-09 0.34
ERG2_YEAST ERG2 C-8 sterol isomerase 1.162e-08 0.34
ANDR_HUMAN AR Androgen receptor 9.637e-08 0.59
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.67e-07 0.59
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.663e-06 0.30
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 3.952e-06 0.59

Fluorometholone

Q690N0_BOVIN PGR Progesterone receptor 3.234e-67 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 8.198e-39 1.00
ANDR_RAT Ar Androgen receptor 1.651e-07 1.00
ATTY_RAT Tat Tyrosine aminotransferase 2.433e-105 0.40
GCR_RAT Nr3c1 Glucocorticoid receptor 5.622e-74 0.50
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 7.894e-46 0.44
SHBG_HUMAN SHBG Sex hormone-binding globulin 2.124e-18 0.35
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.793e-17 0.37
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.221e-11 0.37
GLNA_HUMAN GLUL Glutamine synthetase 1.221e-11 0.37
IL6_HUMAN IL6 Interleukin-6 2.701e-09 0.37
CP19A_HUMAN CYP19A1 Aromatase 6.004e-08 0.38

Levonorgestrel

SHBG_HUMAN SHBG Sex hormone-binding globulin 3.188e-66 1.00
Q690N0_BOVIN PGR Progesterone receptor 2.843e-61 1.00
ANDR_RAT Ar Androgen receptor 1.301e-20 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 2.185e-07 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.3636 1.00
PRGR_RAT Pgr Progesterone receptor 1.337e-35 0.53
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.928e-32 0.31
F1Q298_CANLF NR3C1 Glucocorticoid receptor 6.531e-30 0.37
GCR_PIG NR3C1 Glucocorticoid receptor 6.531e-30 0.37
SHBG_RAT Shbg Sex hormone-binding globulin 1.348e-23 0.29
PRGR_RABIT PGR Progesterone receptor 1.833e-23 0.52
PRGR_HUMAN PGR Progesterone receptor 5.183e-19 0.72
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 1.211e-18 0.30
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 6.556e-18 0.28
ANDR_HUMAN AR Androgen receptor 3.331e-16 0.61
CP19A_HUMAN CYP19A1 Aromatase 6.439e-15 0.51
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.831e-14 0.30
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.233e-09 0.61
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 2.72e-09 0.29
ERG2_YEAST ERG2 C-8 sterol isomerase 7.83e-08 0.30
ANDR_MOUSE Ar Androgen receptor 1.369e-07 0.30
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 2.041e-07 0.30
PPO2_AGABI PPO2 Polyphenol oxidase 2 3.474e-07 0.45
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.369e-06 0.29

Pramipexole

DRD3_RAT Drd3 D(3) dopamine receptor 2.485e-63 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 5.329e-15 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.436e-06 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.0001278 1.00
DRD2_BOVIN DRD2 D(2) dopamine receptor 0.0004316 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 0.1132 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.9968 1.00
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 6.067e-13 0.32

Alfuzosin

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 8.116e-63 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.712e-45 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.704e-45 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 4.571e-24 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 1.147e-21 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 1.152e-21 1.00
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 6.817e-14 1.00
ACES_HUMAN ACHE Acetylcholinesterase 0.001829 1.00
EHMT1_HUMAN EHMT1 Histone-lysine N-methyltransferase EHMT1 1.553e-129 0.47
EHMT2_HUMAN EHMT2 Histone-lysine N-methyltransferase EHMT2 4.299e-83 0.47
CASB_RAT Csn2 Beta-casein 5.789e-46 0.36
KMT5A_HUMAN KMT5A N-lysine methyltransferase KMT5A 1.562e-39 0.37
PDE4B_RAT Pde4b cAMP-specific 3',5'-cyclic phosphodiesterase 4B 9.807e-34 0.31
ADA2A_PIG ADRA2A Alpha-2A adrenergic receptor 5.245e-27 0.33
DRTS_TRYCR Bifunctional dihydrofolate reductase-thymidylate synthase 3.749e-23 0.30
PI3R5_HUMAN PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 4.816e-21 0.30
UHRF1_HUMAN UHRF1 E3 ubiquitin-protein ligase UHRF1 3.809e-18 0.29
Q53I59_TRYCR PDEC Phosphodiesterase 6.661e-16 0.30
ATM_HUMAN ATM Serine-protein kinase ATM 1.887e-15 0.32
SCNNA_MOUSE Scnn1a Amiloride-sensitive sodium channel subunit alpha 6.545e-13 0.32
DYR_PNECA Dihydrofolate reductase 4.491e-09 0.33
ACES_BOVIN ACHE Acetylcholinesterase 1.588e-08 0.34
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 3.013e-08 0.33
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 6.454e-08 0.33
PDE4D_HUMAN PDE4D cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1.318e-07 0.31
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 1.381e-07 0.28
CCR4_HUMAN CCR4 C-C chemokine receptor type 4 2.871e-07 0.33
DYR_RAT Dhfr Dihydrofolate reductase 4.37e-07 0.33
ADA1A_RABIT ADRA1A Alpha-1A adrenergic receptor 3.703e-06 0.51
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 4.327e-06 0.51
RAD52_HUMAN RAD52 DNA repair protein RAD52 homolog 4.552e-06 0.34
DPOL_VACCW POL DNA polymerase 5.02e-06 0.29
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.112e-06 0.29

Remoxipride

DRD2_RAT Drd2 D(2) dopamine receptor 7.469e-62 1.00
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.645e-26 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 2.688e-26 1.00
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.11e-16 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 3.331e-16 1.00
DRD4_HUMAN DRD4 D(4) dopamine receptor 1.443e-15 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.002272 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.09659 1.00
Q25856_PLAFA PFG6PD Glucose-6-phosphate dehydrogenase 2.347e-92 0.45
DRD2_CANLF DRD2 D(2) dopamine receptor 5.709e-77 0.62
GLUPH_PLAF7 Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase 4.466e-60 0.38
S29A2_RAT Slc29a2 Equilibrative nucleoside transporter 2 2.07e-38 0.30
PDE5A_CANLF PDE5A cGMP-specific 3',5'-cyclic phosphodiesterase 5.796e-36 0.33
DRD3_RAT Drd3 D(3) dopamine receptor 1.269e-31 0.61
SC5A7_HUMAN SLC5A7 High affinity choline transporter 1 1.152e-26 0.34
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.109e-26 0.38
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 5.97e-26 0.36
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 1.093e-23 0.32
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 8.494e-22 0.34
O77823_PIG PDE4A Cyclic AMP-specific phosphodiesterase SSPDE4A1A 5.752e-21 0.34
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 2.687e-20 0.30
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 4.441e-16 0.34
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 9.992e-16 0.30
NLRP3_MOUSE Nlrp3 NACHT, LRR and PYD domains-containing protein 3 1.443e-15 0.29
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.665e-14 0.76
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 9.936e-14 0.31
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 2.133e-13 0.45
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 6.764e-12 0.53
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 2.874e-11 0.35
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 1.479e-10 0.28
SEPR_MOUSE Fap Prolyl endopeptidase FAP 2.395e-10 0.32
HCN4_HUMAN HCN4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 3.367e-10 0.30
AA2BR_RAT Adora2b Adenosine receptor A2b 4.678e-10 0.30
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 5.096e-10 0.32
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 5.484e-10 0.37
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 5.504e-10 0.62
SMAD3_HUMAN SMAD3 Mothers against decapentaplegic homolog 3 6.299e-10 0.40
MTR1A_HUMAN MTNR1A Melatonin receptor type 1A 1.728e-09 0.34
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.595e-09 0.62
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 2.751e-09 0.29
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 4.608e-09 0.28
CAN_YEAST NCE103 Carbonic anhydrase 6.324e-09 0.62
ACHA5_HUMAN CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 8.147e-09 0.31
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.222e-08 0.35
PTAFR_CAVPO PTAFR Platelet-activating factor receptor 1.234e-08 0.32
C0IX24_STYPI CA2 Carbonic anhydrase 1.406e-08 0.62
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.406e-08 0.62
B2V8E3_SULSY Carbonate dehydratase 2.891e-08 0.62
B5SU02_STYPI CA Alpha carbonic anhydrase 2.891e-08 0.62
Q31FD6_HYDCU Carbonic anhydrase, alpha family 2.891e-08 0.62
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 3.289e-08 0.33
A6YCJ1_9METZ Astrosclerin-3 7.553e-08 0.62
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.526e-07 0.36
DRD1_RAT Drd1 D(1A) dopamine receptor 1.918e-07 0.68
CAH6_HUMAN CA6 Carbonic anhydrase 6 2.152e-07 0.62
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 2.286e-07 0.33
CYNT_HELPY cynT Carbonic anhydrase 3.688e-07 0.62
MIP_LEGPN mip Outer membrane protein MIP 4.44e-07 0.30
MTR1B_CHICK Melatonin receptor type 1B 6.013e-07 0.28
KCNK3_HUMAN KCNK3 Potassium channel subfamily K member 3 6.754e-07 0.31
ENV_HV1Y2 env Envelope glycoprotein gp160 7.85e-07 0.42
Q9JKC1_RAT Bche Carboxylic ester hydrolase 1.005e-06 0.30
OX2R_HUMAN HCRTR2 Orexin receptor type 2 1.521e-06 0.36
PLD1_RAT Pld1 Phospholipase D1 1.988e-06 0.32
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 2.147e-06 0.29
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 3.559e-06 0.29
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 4.021e-06 0.36
MBTP1_HUMAN MBTPS1 Membrane-bound transcription factor site-1 protease 4.73e-06 0.31
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 7.652e-06 0.28

Methylphenidate

SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 4.565e-60 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 1.007e-31 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.856e-17 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 6.379e-13 1.00
Q9WTR4_RAT Slc6a2 Transporter 1.501e-08 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.982e-54 0.32
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 1.371e-38 0.32
IL2RA_HUMAN IL2RA Interleukin-2 receptor subunit alpha 7.142e-37 0.29
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 2.067e-32 0.32
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 7.308e-31 0.33
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.257e-28 0.33
BLAB_BACCE Metallo-beta-lactamase type 2 3.797e-28 0.32
PPME1_HUMAN PPME1 Protein phosphatase methylesterase 1 1.246e-25 0.32
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 1.819e-25 0.34
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 8.806e-25 0.33
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 7.69e-23 0.35
NK1R_RAT Tacr1 Substance-P receptor 1.073e-22 0.37
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.908e-21 0.35
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 2.796e-20 0.29
KCNQ4_HUMAN KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 1.753e-18 0.29
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 1.91e-18 0.35
Q5TKS5_STAAU fabI Enoyl-ACP reductase 5.342e-18 0.29
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 2.366e-17 0.38
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.11e-16 0.44
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 1.11e-16 0.29
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.887e-15 0.46
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 1.887e-15 0.29
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.665e-15 0.36
NK1R_MOUSE Tacr1 Substance-P receptor 2.665e-15 0.29
MA2A1_HUMAN MAN2A1 Alpha-mannosidase 2 4.441e-15 0.29
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 5.107e-15 0.29
MA1B1_HUMAN MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1.166e-14 0.29
MRGX1_HUMAN MRGPRX1 Mas-related G-protein coupled receptor member X1 1.976e-14 0.32
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 2.121e-14 0.36
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 5.107e-14 0.29
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.961e-13 0.38
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 2.138e-13 0.33
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 3.184e-13 0.28
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.458e-13 0.32
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 3.99e-13 0.31
KYNU_HUMAN KYNU Kynureninase 4.967e-13 0.28
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 1.252e-12 0.34
Q7JHP9_MACMU SLC6A3 Transporter 1.604e-12 0.30
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 5.06e-12 0.29
NK1R_HUMAN TACR1 Substance-P receptor 5.916e-12 0.39
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 5.963e-12 0.29
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 9.267e-12 0.31
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 9.7e-12 0.29
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 9.7e-12 0.29
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.171e-11 0.35
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 2.363e-11 0.31
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 9.617e-11 0.29
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.02e-10 0.29
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 1.105e-10 0.29
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 1.415e-10 0.31
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 2.262e-10 0.43
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 2.317e-10 0.34
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 2.538e-10 0.33
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 2.882e-10 0.35
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.984e-10 0.35
SC6A3_BOVIN SLC6A3 Sodium-dependent dopamine transporter 3.022e-10 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 3.304e-10 0.70
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 4.109e-10 0.33
MLX_HUMAN MLX Max-like protein X 7.541e-10 0.29
Q27552_CRYPV DHFR-TS Bifunctional dihydrofolate reductase-thymidylate synthase 1.448e-09 0.29
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 1.497e-09 0.33
DPP2_HUMAN DPP7 Dipeptidyl peptidase 2 1.876e-09 0.33
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.98e-09 0.41
PPCE_BOVIN PREP Prolyl endopeptidase 2.184e-09 0.29
Q9SEH8_SOYBN Man1 alpha-1,2-Mannosidase 2.304e-09 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.616e-09 0.35
Q8WMX0_BOVIN Muscarinic receptor M1 5.129e-09 0.32
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 6.016e-09 0.32
Q8WSF8_APLCA Soluble acetylcholine receptor 6.075e-09 0.29
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 1.096e-08 0.32
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.147e-08 0.33
TAAR1_RAT Taar1 Trace amine-associated receptor 1 1.64e-08 0.39
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 1.881e-08 0.33
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.293e-08 0.35
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 2.365e-08 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.659e-08 0.35
IL2RA_MOUSE Il2ra Interleukin-2 receptor subunit alpha 2.8e-08 0.29
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 3.985e-08 0.29
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 4.403e-08 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.692e-08 0.38
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.707e-08 0.29
PPCE_HUMAN PREP Prolyl endopeptidase 8.639e-08 0.33
TRYB1_HUMAN TPSAB1 Tryptase alpha/beta-1 1.311e-07 0.33
DPP4_HUMAN DPP4 Dipeptidyl peptidase 4 1.351e-07 0.38
ACHP_LYMST Acetylcholine-binding protein 1.361e-07 0.29
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 1.383e-07 0.32
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 1.749e-07 0.41
O31048_PORGN DPP IV Dipeptidyl peptidase IV 2.06e-07 0.29
THRB_HUMAN F2 Prothrombin 2.184e-07 0.34
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.337e-07 0.35
MMP13_RAT Mmp13 Collagenase 3 2.362e-07 0.29
MGLL_RAT Mgll Monoglyceride lipase 3.455e-07 0.30
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 3.574e-07 0.34
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 3.591e-07 0.32
MAP2_HUMAN METAP2 Methionine aminopeptidase 2 4.7e-07 0.34
NK3R_HUMAN TACR3 Neuromedin-K receptor 5.524e-07 0.37
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 5.796e-07 0.32
OPRX_HUMAN OPRL1 Nociceptin receptor 1.144e-06 0.38
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.615e-06 0.31
MMP12_MOUSE Mmp12 Macrophage metalloelastase 1.858e-06 0.28
BLA2_BACCE blm Metallo-beta-lactamase type 2 1.938e-06 0.32
MTR1B_HUMAN MTNR1B Melatonin receptor type 1B 2.805e-06 0.32
KLK5_HUMAN KLK5 Kallikrein-5 2.849e-06 0.29
LSHR_HUMAN LHCGR Lutropin-choriogonadotropic hormone receptor 2.917e-06 0.30
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 2.994e-06 0.33
AMPL_PIG LAP3 Cytosol aminopeptidase 3.596e-06 0.33
TS1R1_HUMAN TAS1R1 Taste receptor type 1 member 1 4.142e-06 0.29
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 5.377e-06 0.32
CATK_HUMAN CTSK Cathepsin K 5.537e-06 0.31
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 8.364e-06 0.29
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 8.372e-06 0.29

Codeine

OPRM_HUMAN OPRM1 Mu-type opioid receptor 4.923e-59 1.00
OPRX_CAVPO OPRL1 Nociceptin receptor 1.98e-140 0.77
OPRD_HUMAN OPRD1 Delta-type opioid receptor 8.133e-64 0.79
OPRM_CAVPO OPRM1 Mu-type opioid receptor 4.473e-55 0.77
OPRM_BOVIN OPRM1 Mu-type opioid receptor 2.502e-49 0.41
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 1.171e-48 0.77
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 4.123e-48 0.79
OPRM_MOUSE Oprm1 Mu-type opioid receptor 7.323e-39 0.79
OPRM_RAT Oprm1 Mu-type opioid receptor 7.836e-33 0.79
OPRD_RAT Oprd1 Delta-type opioid receptor 8.666e-32 0.51
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 3.864e-24 0.54
ACES_TETCF ache Acetylcholinesterase 2.323e-22 0.41
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.236e-19 0.51
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.341e-19 0.79
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 4.312e-19 0.38
Q9JKC1_RAT Bche Carboxylic ester hydrolase 3.538e-17 0.41
ACES_RAT Ache Acetylcholinesterase 6.661e-16 0.41
KCNN1_HUMAN KCNN1 Small conductance calcium-activated potassium channel protein 1 3.598e-09 0.29
KCNN2_HUMAN KCNN2 Small conductance calcium-activated potassium channel protein 2 1.031e-07 0.29
OX1R_HUMAN HCRTR1 Orexin receptor type 1 1.735e-07 0.34
SSR1_RAT Sstr1 Somatostatin receptor type 1 3.097e-07 0.29

Timolol

B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.668e-56 1.00
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.36e-53 1.00
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 4.955e-21 1.00
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 5.011e-19 1.00
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 1.11e-16 1.00
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 3.331e-16 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.8514 1.00
LICH_HUMAN LIPA Lysosomal acid lipase/cholesteryl ester hydrolase 2.461e-84 0.48
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 2.476e-14 0.35
KCNQ3_HUMAN KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 8.542e-11 0.32
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 3.026e-08 0.36
Q8I5C5_PLAF7 Macrophage migration inhibitory factor 2.587e-06 0.29
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 5.919e-06 0.32

Palonosetron

5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 1.048e-50 1.00
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.089e-50 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9983 1.00
Q8WMX0_BOVIN Muscarinic receptor M1 1.494e-24 0.30
5HT3A_MOUSE Htr3a 5-hydroxytryptamine receptor 3A 3.087e-20 0.47
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 4.455e-17 0.32
ACHA7_RAT Chrna7 Neuronal acetylcholine receptor subunit alpha-7 9.77e-15 0.36
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 3.132e-13 0.34
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 9.701e-12 0.32
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 9.787e-12 0.34
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.031e-07 0.29
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.68e-07 0.28
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 8.041e-06 0.34

Phenylephrine

G3HDX1_CRIGR Alpha-1B adrenergic receptor 1.089e-50 1.00
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 1.307e-06 1.00
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 1.599e-05 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.002267 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 0.004872 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.01053 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.03213 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 0.04974 1.00
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 0.3731 1.00
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.226e-76 0.70
ADRB2_RAT Adrb2 Beta-2 adrenergic receptor 2.208e-65 0.41
KYNU_RAT Kynu Kynureninase 5.398e-61 0.49
SYFA_STAAU pheS Phenylalanine--tRNA ligase alpha subunit 3.223e-56 0.39
ADRB2_HUMAN ADRB2 Beta-2 adrenergic receptor 2.091e-44 0.61
ADRB3_HUMAN ADRB3 Beta-3 adrenergic receptor 9.24e-42 0.41
ADRB1_MOUSE Adrb1 Beta-1 adrenergic receptor 1.847e-40 0.41
ADA2A_MOUSE Adra2a Alpha-2A adrenergic receptor 7.545e-40 0.32
ADA2C_MOUSE Adra2c Alpha-2C adrenergic receptor 7.545e-40 0.32
ADRB1_HUMAN ADRB1 Beta-1 adrenergic receptor 7.685e-32 0.41
PLCG1_BOVIN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5.173e-29 0.28
PPO1_AGABI PPO1 Polyphenol oxidase 1 4.291e-27 0.33
ADRB2_CANLF ADRB2 Beta-2 adrenergic receptor 4.878e-26 0.61
H9TVJ1_CHISP TyR1 7.913e-25 0.31
ADRB1_RAT Adrb1 Beta-1 adrenergic receptor 1.29e-23 0.49
GABT_PIG ABAT 4-aminobutyrate aminotransferase, mitochondrial 5.481e-22 0.35
KYNU_HUMAN KYNU Kynureninase 8.171e-22 0.49
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 1.428e-21 0.40
ADRB3_RAT Adrb3 Beta-3 adrenergic receptor 4.481e-21 0.41
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 8.596e-19 0.30
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 9.008e-19 0.61
ADRB2_MESAU ADRB2 Beta-2 adrenergic receptor 1.686e-18 0.41
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 1.11e-16 0.47
Q2PCB5_DICLA ca Carbonic anhydrase 2.176e-14 0.39
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.161e-13 0.47
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.201e-13 0.45
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 1.233e-13 0.40
VMAT2_BOVIN SLC18A2 Synaptic vesicular amine transporter 1.517e-10 0.31
TYRO_HUMAN TYR Tyrosinase 2.725e-09 0.31
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.674e-08 0.32
DHB1_HUMAN HSD17B1 Estradiol 17-beta-dehydrogenase 1 3.438e-08 0.33
SPRE_HUMAN SPR Sepiapterin reductase 3.632e-08 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 8.826e-08 0.36
DHB2_HUMAN HSD17B2 Estradiol 17-beta-dehydrogenase 2 8.864e-08 0.33
CTBP2_HUMAN CTBP2 C-terminal-binding protein 2 9.771e-08 0.30
ADRB3_CANLF ADRB3 Beta-3 adrenergic receptor 2.194e-07 0.29
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 1.204e-06 0.34
OPRM_RAT Oprm1 Mu-type opioid receptor 1.418e-06 0.39
Q8WSF8_APLCA Soluble acetylcholine receptor 4.248e-06 0.38

Spironolactone

Q690N0_BOVIN PGR Progesterone receptor 1.337e-49 1.00
ANDR_RAT Ar Androgen receptor 7.189e-22 1.00
ANDR_HUMAN AR Androgen receptor 4.585e-14 1.00
MCR_HUMAN NR3C2 Mineralocorticoid receptor 9.694e-12 1.00
GCR_HUMAN NR3C1 Glucocorticoid receptor 5.952e-08 1.00
PRGR_HUMAN PGR Progesterone receptor 1.825e-07 1.00
ESR2_HUMAN ESR2 Estrogen receptor beta 0.1078 1.00
ESR1_HUMAN ESR1 Estrogen receptor 0.5902 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.6144 1.00
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 3.372e-60 0.42
SHBG_HUMAN SHBG Sex hormone-binding globulin 5.299e-54 0.50
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.989e-42 0.37
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 7.263e-34 0.37
CP19A_HUMAN CYP19A1 Aromatase 3.539e-32 0.48
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 4.362e-30 0.40
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 8.507e-26 0.40
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 5.168e-23 0.41
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 3.374e-21 0.34
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 4.049e-21 0.37
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.984e-19 0.31
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 6.229e-18 0.28
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 5.076e-17 0.35
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.887e-15 0.33
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.177e-14 0.40
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.118e-13 0.37
PRGR_RAT Pgr Progesterone receptor 4.751e-13 0.28
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.302e-12 0.40
ANDR_MOUSE Ar Androgen receptor 3.366e-12 0.40
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.681e-11 0.34
PRGR_RABIT PGR Progesterone receptor 1.943e-10 0.40
ERG2_YEAST ERG2 C-8 sterol isomerase 2.27e-10 0.40
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.735e-10 0.40
AK1C3_HUMAN AKR1C3 Aldo-keto reductase family 1 member C3 2.572e-09 0.35
CP19A_RAT Cyp19a1 Aromatase 9.937e-06 0.38

Ipratropium

ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.783e-46 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.528e-27 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.219e-24 1.00
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.662e-23 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.494e-21 1.00
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 8.084e-19 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.11e-16 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 4.301e-12 1.00
Q8VH25_CAVPO GPM4 Muscarinic acetylcholine receptor 1.016e-80 0.65
Q8WSF8_APLCA Soluble acetylcholine receptor 1.857e-63 0.47
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 4.263e-50 0.80
ACER2_HUMAN ACER2 Alkaline ceramidase 2 1.579e-38 0.31
ACHP_LYMST Acetylcholine-binding protein 8.381e-37 0.47
CERT_HUMAN CERT1 Ceramide transfer protein 3.875e-36 0.29
AMYP_RAT Amy2 Pancreatic alpha-amylase 6.646e-26 0.30
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.058e-25 0.63
GLRA1_RAT Glra1 Glycine receptor subunit alpha-1 2.046e-23 0.31
GPR88_HUMAN GPR88 Probable G-protein coupled receptor 88 3.813e-22 0.36
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 5.223e-19 0.65
Q8WMX0_BOVIN Muscarinic receptor M1 1.237e-17 0.63
ACHA7_MOUSE Chrna7 Neuronal acetylcholine receptor subunit alpha-7 1.11e-16 0.37
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 5.551e-16 0.35
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 9.992e-16 0.63
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 7.661e-15 0.80
ACE_MOUSE Ace Angiotensin-converting enzyme 1.215e-13 0.29
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 5.45e-13 0.63
MRGX1_RAT Mrgprx1 Mas-related G-protein coupled receptor member X1 5.731e-11 0.29
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 6.004e-11 0.32
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.41e-09 0.28
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.633e-08 0.35
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.661e-08 0.34
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 1.176e-07 0.65
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.815e-07 0.35
ACHA7_HUMAN CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 4.337e-07 0.47
KCNQ2_HUMAN KCNQ2 Potassium voltage-gated channel subfamily KQT member 2 5.697e-07 0.29
AA1R_BOVIN ADORA1 Adenosine receptor A1 7.007e-07 0.32
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.041e-06 0.35
AMPL_PIG LAP3 Cytosol aminopeptidase 2.472e-06 0.34
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 5.934e-06 0.80

Procyclidine

ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.818e-46 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.001e-42 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.777e-39 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.801e-26 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.684e-25 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.818e-20 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.625e-12 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.281e-06 1.00
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.091e-89 0.39
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.259e-74 0.40
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.311e-58 0.36
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.53e-57 0.33
ABHDB_HUMAN ABHD11 Protein ABHD11 6.795e-57 0.33
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 5.348e-55 0.50
HRH3_HUMAN HRH3 Histamine H3 receptor 1.264e-53 0.39
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 3.021e-49 0.35
MEN1_HUMAN MEN1 Menin 1.691e-47 0.46
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.218e-45 0.41
DGLB_MOUSE Daglb Sn1-specific diacylglycerol lipase beta 2.533e-43 0.36
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 7.365e-43 0.43
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.733e-42 0.42
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 3.028e-39 0.35
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.01e-38 0.39
NPSR1_RAT Npsr1 Neuropeptide S receptor 1.381e-38 0.31
HRH3_MOUSE Hrh3 Histamine H3 receptor 4.085e-38 0.38
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.358e-31 0.36
HNMT_RAT Hnmt Histamine N-methyltransferase 1.753e-29 0.33
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.098e-29 0.39
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.306e-29 0.52
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 7.118e-29 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 6.688e-28 0.40
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.257e-27 0.42
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 1.133e-26 0.36
Q8WMX0_BOVIN Muscarinic receptor M1 2.148e-24 0.30
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.087e-23 0.31
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.954e-23 0.34
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 1.73e-21 0.31
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.338e-21 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.304e-20 0.56
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.443e-17 0.43
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 3.774e-17 0.33
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.11e-16 0.36
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.11e-16 0.32
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 9.548e-15 0.40
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 2.598e-14 0.32
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.275e-14 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 8.071e-14 0.37
HRH1_HUMAN HRH1 Histamine H1 receptor 1.079e-13 0.44
TYTR_TRYBB TPR Trypanothione reductase 4.239e-13 0.32
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.249e-12 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.722e-12 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.513e-12 0.36
TERT_HUMAN TERT Telomerase reverse transcriptase 2.922e-12 0.33
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.605e-12 0.35
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 8.624e-12 0.33
CALM_BOVIN CALM Calmodulin 2.119e-11 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.551e-11 0.34
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 9.019e-11 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.841e-10 0.37
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.162e-10 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 5.581e-10 0.38
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.417e-10 0.42
PPCE_BOVIN PREP Prolyl endopeptidase 1.076e-09 0.30
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.117e-09 0.44
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.533e-09 0.29
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 2.681e-09 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.864e-09 0.28
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 5.529e-09 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.822e-08 0.32
DPO1_THEAQ polA DNA polymerase I, thermostable 3.921e-08 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 8.033e-08 0.32
HRH2_HUMAN HRH2 Histamine H2 receptor 1.249e-07 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.346e-07 0.30
ESR1_HUMAN ESR1 Estrogen receptor 1.427e-07 0.33
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.643e-07 0.34
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 3.393e-07 0.37
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.513e-07 0.32
OPRX_HUMAN OPRL1 Nociceptin receptor 5.254e-07 0.33
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.684e-06 0.29
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 1.955e-06 0.31
Q63380_RAT NET Transporter 2.019e-06 0.33
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 3.168e-06 0.28
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.426e-06 0.31
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.669e-06 0.39
ACES_MOUSE Ache Acetylcholinesterase 3.702e-06 0.35
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.82e-06 0.38
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.618e-06 0.32
ACHP_LYMST Acetylcholine-binding protein 5.32e-06 0.32
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.095e-06 0.56
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 6.522e-06 0.30
HRH3_CAVPO HRH3 Histamine H3 receptor 7.767e-06 0.36
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 7.804e-06 0.38

Trihexyphenidyl

ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 9.818e-46 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.001e-42 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.777e-39 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 9.801e-26 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.684e-25 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 7.818e-20 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.625e-12 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 1.281e-06 1.00
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 1.091e-89 0.39
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 3.259e-74 0.40
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 1.311e-58 0.36
AMYP_RAT Amy2 Pancreatic alpha-amylase 4.53e-57 0.33
ABHDB_HUMAN ABHD11 Protein ABHD11 6.795e-57 0.33
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 5.348e-55 0.50
HRH3_HUMAN HRH3 Histamine H3 receptor 1.264e-53 0.39
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 3.021e-49 0.35
MEN1_HUMAN MEN1 Menin 1.691e-47 0.46
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 3.218e-45 0.41
DGLB_MOUSE Daglb Sn1-specific diacylglycerol lipase beta 2.533e-43 0.36
PSB1_HUMAN PSMB1 Proteasome subunit beta type-1 7.365e-43 0.43
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.733e-42 0.42
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 3.028e-39 0.35
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.01e-38 0.39
NPSR1_RAT Npsr1 Neuropeptide S receptor 1.381e-38 0.31
HRH3_MOUSE Hrh3 Histamine H3 receptor 4.085e-38 0.38
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 1.358e-31 0.36
HNMT_RAT Hnmt Histamine N-methyltransferase 1.753e-29 0.33
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 2.098e-29 0.39
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.306e-29 0.52
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 7.118e-29 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 6.688e-28 0.40
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 9.257e-27 0.42
NPSR1_HUMAN NPSR1 Neuropeptide S receptor 1.133e-26 0.36
Q8WMX0_BOVIN Muscarinic receptor M1 2.148e-24 0.30
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 1.087e-23 0.31
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 8.954e-23 0.34
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 1.73e-21 0.31
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.338e-21 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.304e-20 0.56
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 1.443e-17 0.43
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 3.774e-17 0.33
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.11e-16 0.36
S6A11_HUMAN SLC6A11 Sodium- and chloride-dependent GABA transporter 3 1.11e-16 0.32
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 9.548e-15 0.40
S6A11_MOUSE Slc6a11 Sodium- and chloride-dependent GABA transporter 3 2.598e-14 0.32
LMBL3_HUMAN L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 3.275e-14 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 8.071e-14 0.37
HRH1_HUMAN HRH1 Histamine H1 receptor 1.079e-13 0.44
TYTR_TRYBB TPR Trypanothione reductase 4.239e-13 0.32
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 1.249e-12 0.36
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 1.722e-12 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 2.513e-12 0.36
TERT_HUMAN TERT Telomerase reverse transcriptase 2.922e-12 0.33
VMAT2_RAT Slc18a2 Synaptic vesicular amine transporter 4.605e-12 0.35
VACHT_RAT Slc18a3 Vesicular acetylcholine transporter 8.624e-12 0.33
CALM_BOVIN CALM Calmodulin 2.119e-11 0.31
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.551e-11 0.34
NMD3A_RAT Grin3a Glutamate receptor ionotropic, NMDA 3A 9.019e-11 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 3.841e-10 0.37
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 5.162e-10 0.29
HRH1_CAVPO HRH1 Histamine H1 receptor 5.581e-10 0.38
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 9.417e-10 0.42
PPCE_BOVIN PREP Prolyl endopeptidase 1.076e-09 0.30
KCNA3_HUMAN KCNA3 Potassium voltage-gated channel subfamily A member 3 1.117e-09 0.44
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.533e-09 0.29
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 2.681e-09 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.864e-09 0.28
ANM8_HUMAN PRMT8 Protein arginine N-methyltransferase 8 5.529e-09 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.822e-08 0.32
DPO1_THEAQ polA DNA polymerase I, thermostable 3.921e-08 0.33
ESR2_HUMAN ESR2 Estrogen receptor beta 8.033e-08 0.32
HRH2_HUMAN HRH2 Histamine H2 receptor 1.249e-07 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.346e-07 0.30
ESR1_HUMAN ESR1 Estrogen receptor 1.427e-07 0.33
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 2.643e-07 0.34
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 3.393e-07 0.37
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.513e-07 0.32
OPRX_HUMAN OPRL1 Nociceptin receptor 5.254e-07 0.33
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 1.684e-06 0.29
LKHA4_MOUSE Lta4h Leukotriene A-4 hydrolase 1.955e-06 0.31
Q63380_RAT NET Transporter 2.019e-06 0.33
FKB1A_RAT Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 3.168e-06 0.28
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 3.426e-06 0.31
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 3.669e-06 0.39
ACES_MOUSE Ache Acetylcholinesterase 3.702e-06 0.35
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.82e-06 0.38
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 4.618e-06 0.32
ACHP_LYMST Acetylcholine-binding protein 5.32e-06 0.32
DRD3_HUMAN DRD3 D(3) dopamine receptor 6.095e-06 0.56
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 6.522e-06 0.30
HRH3_CAVPO HRH3 Histamine H3 receptor 7.767e-06 0.36
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 7.804e-06 0.38

Piperacillin

A2RP81_CITFR blaPER-2 Beta-lactamase 6.524e-44 1.00
STRP_STRP1 ska Streptokinase A 0.0006681 1.00
Q82134_9DELA prt Protease 1.273e-124 0.32
Q82323_9DELA Protease 5.568e-90 0.32
PRO_HTL1A gag-pro Gag-Pro polyprotein 3.513e-61 0.33
BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 2.032e-58 0.32
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 5.435e-33 0.41
BLAB_BACCE Metallo-beta-lactamase type 2 5.597e-33 0.37
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.085e-31 0.36
Q3S5C3_SALNE sugE Efflux transporter 1.705e-25 0.41
Q48435_KLEPN bla LAT-2 Beta-lactamase 1.705e-25 0.41
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.529e-23 0.29
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.665e-23 0.47
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 1.095e-20 0.35
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 6.661e-16 0.47
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.132e-14 0.47
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.343e-14 0.32
CATL1_RAT Ctsl Cathepsin L1 3.402e-11 0.35
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.064e-08 0.29
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 1.453e-08 0.28
A5Z252_9INFA Neuraminidase 4.695e-07 0.29
AMPC_ECOLI ampC Beta-lactamase 4.736e-07 0.38
NRAM_I77AB Neuraminidase 3.213e-06 0.29

Rosiglitazone

PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 9.026e-44 1.00
RARG_HUMAN RARG Retinoic acid receptor gamma 0.0009832 1.00
MPC2_HUMAN MPC2 Mitochondrial pyruvate carrier 2 7.666e-77 0.48
CISD1_RAT Cisd1 CDGSH iron-sulfur domain-containing protein 1 6.154e-72 0.53
FFAR1_HUMAN FFAR1 Free fatty acid receptor 1 8.859e-38 0.57
ABCBB_RAT Abcb11 Bile salt export pump 1.306e-36 0.53
PPARG_MOUSE Pparg Peroxisome proliferator-activated receptor gamma 4.609e-25 0.66
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 7.201e-25 0.53
ABCBB_HUMAN ABCB11 Bile salt export pump 3.276e-21 0.53
PPARG_RAT Pparg Peroxisome proliferator-activated receptor gamma 3.323e-18 0.53
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 2.886e-17 0.35
SC5A5_RAT Slc5a5 Sodium/iodide cotransporter 5.551e-16 0.35
ERG2_YEAST ERG2 C-8 sterol isomerase 1.321e-14 0.29
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 1.692e-13 0.62
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 9.075e-13 0.30
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1.815e-12 0.29
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 1.032e-11 0.29
Q690N0_BOVIN PGR Progesterone receptor 1.913e-11 0.50
HRH1_CAVPO HRH1 Histamine H1 receptor 5.783e-09 0.41
PGDH_HUMAN HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 7.283e-09 0.50
PPARA_MOUSE Ppara Peroxisome proliferator-activated receptor alpha 4.735e-08 0.34
ERR3_MOUSE Esrrg Estrogen-related receptor gamma 5.058e-08 0.28
RORA_HUMAN RORA Nuclear receptor ROR-alpha 1.063e-06 0.33
PDE6D_HUMAN PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 2.213e-06 0.31
TP4A3_HUMAN PTP4A3 Protein tyrosine phosphatase type IVA 3 4.225e-06 0.29
PPARD_HUMAN PPARD Peroxisome proliferator-activated receptor delta 5.627e-06 0.35

Aminohippuric_acid

S22A6_MOUSE Slc22a6 Solute carrier family 22 member 6 1.735e-32 1.00
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 2.531e-21 1.00
EGLN1_RAT Egln1 Egl nine homolog 1 2.48e-84 0.33
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.04e-71 0.40
EGLN1_HUMAN EGLN1 Egl nine homolog 1 8.519e-48 0.40
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 1.034e-37 0.33
ECR_CHITE EcR Ecdysone receptor 7.142e-37 0.29
ECR_HELVI EcR Ecdysone receptor 7.142e-37 0.29
O45117_CHITE USP-1 Ultraspiracle 7.142e-37 0.29
Q6IVK1_PLOIN USP 7.142e-37 0.29
Q6RVD3_PLOIN Ecdysone receptor 7.142e-37 0.29
Q7SIF6_HELVI Gene regulation protein 7.142e-37 0.29
Q8I1M8_CHISP CsUSP Ultraspiracle 7.142e-37 0.29
Q8MYA6_CHISP CsEcR-B1 Ecdysone receptor B1 isoform 7.142e-37 0.29
Q962I5_LUCCU Ultraspiracle protein 7.142e-37 0.29
USP_CHOFU USP Protein ultraspiracle homolog 7.142e-37 0.29
EGLN3_HUMAN EGLN3 Egl nine homolog 3 7.525e-32 0.36
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 1.275e-29 0.37
CAH2_HUMAN CA2 Carbonic anhydrase 2 1.218e-28 0.64
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 6.264e-27 0.38
PPIB_HUMAN PPIB Peptidyl-prolyl cis-trans isomerase B 2.63e-23 0.35
S22A1_MOUSE Slc22a1 Solute carrier family 22 member 1 5.992e-23 0.51
NR1H4_HUMAN NR1H4 Bile acid receptor 2.358e-22 0.41
PPID_HUMAN PPID Peptidyl-prolyl cis-trans isomerase D 2.889e-22 0.35
METC_ECOLI metC Cystathionine beta-lyase MetC 1.221e-21 0.33
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.239e-21 0.44
E3UJZ5_SPOLI Ecdysone receptor 1.43e-21 0.30
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 9.143e-21 0.38
USP_DROME usp Protein ultraspiracle 4.198e-20 0.30
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 5.223e-20 0.38
ECR_BOMMO EcR Ecdysone receptor 7.147e-20 0.30
COMT_PIG COMT Catechol O-methyltransferase 2.55e-19 0.34
SEPR_MOUSE Fap Prolyl endopeptidase FAP 2.629e-19 0.35
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 1.28e-18 0.51
Q4W6C8_LEPDE LdUSP Ultraspiracle 2.139e-18 0.29
Q4W6D0_LEPDE LdEcR-A Ecdysone receptor A isoform 2.139e-18 0.29
HDAC3_HUMAN HDAC3 Histone deacetylase 3 2.177e-18 0.37
ITA2B_HUMAN ITGA2B Integrin alpha-IIb 2.299e-18 0.51
Q94F81_MAIZE hda106 HD2 type histone deacetylase HDA106 6.516e-18 0.33
CAH4_BOVIN CA4 Carbonic anhydrase 4 9.209e-18 0.64
HDAC2_HUMAN HDAC2 Histone deacetylase 2 1.046e-17 0.41
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 1.683e-17 0.51
BODG_PSESK Gamma-butyrobetaine dioxygenase 3.088e-17 0.38
ECR_DROME EcR Ecdysone receptor 1.11e-16 0.30
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 1.11e-16 0.36
Q9I056_PSEAE cpg2 Carboxypeptidase G2 2.22e-16 0.36
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 3.331e-16 0.33
FOLH1_HUMAN FOLH1 Glutamate carboxypeptidase 2 5.551e-16 0.40
ITB3_HUMAN ITGB3 Integrin beta-3 5.551e-16 0.51
CGAS_HUMAN CGAS Cyclic GMP-AMP synthase 6.661e-16 0.30
Q9GSG8_AEDAE Ultraspiracle isoform-A 2.22e-15 0.29
NEP_RAT Mme Neprilysin 6.55e-15 0.38
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 7.327e-15 0.49
AOC2_HUMAN AOC2 Retina-specific copper amine oxidase 6.761e-14 0.34
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 1.69e-12 0.31
HYES_RAT Ephx2 Bifunctional epoxide hydrolase 2 2.932e-12 0.37
H9B8T9_CAPHI CTSB Cathepsin B 2.97e-12 0.41
DCMC_HUMAN MLYCD Malonyl-CoA decarboxylase, mitochondrial 3.868e-12 0.35
CAH2_BOVIN CA2 Carbonic anhydrase 2 4.489e-12 0.36
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 5.371e-12 0.36
HDAC6_HUMAN HDAC6 Histone deacetylase 6 9.219e-12 0.41
ELNE_MOUSE Elane Neutrophil elastase 9.7e-12 0.29
Q9FD53_STREE mvaD Diphosphomevalonate decarboxylase 2.175e-11 0.31
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 2.582e-11 0.38
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 2.655e-11 0.37
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 3.261e-11 0.40
LGUL_YEAST GLO1 Lactoylglutathione lyase 6.135e-11 0.29
CAH1_HUMAN CA1 Carbonic anhydrase 1 6.46e-11 0.64
ENPP3_HUMAN ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 8.319e-11 0.34
Q2PCB5_DICLA ca Carbonic anhydrase 1.577e-10 0.28
NEUR1_HUMAN NEU1 Sialidase-1 1.647e-10 0.28
Q6DMN0_TOXGO CPL Cathepsin L 7.541e-10 0.29
PPIG_HUMAN PPIG Peptidyl-prolyl cis-trans isomerase G 1.206e-09 0.30
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 1.706e-09 0.36
VE1_HPV11 E1 Replication protein E1 2.122e-09 0.35
ECR_LUCCU EcR Ecdysone receptor 2.406e-09 0.29
NEP_HUMAN MME Neprilysin 5.401e-09 0.37
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 1.129e-08 0.44
ENTK_HUMAN TMPRSS15 Enteropeptidase 1.144e-08 0.43
STXA_SHIDY stxA Shiga toxin subunit A 2.422e-08 0.29
HDAC8_HUMAN HDAC8 Histone deacetylase 8 3.71e-08 0.41
A0A072ZLE6_PSEAI mvfR LysR family transcriptional regulator 3.985e-08 0.29
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 4.069e-08 0.49
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 4.208e-08 0.32
NCOR1_HUMAN NCOR1 Nuclear receptor corepressor 1 7.083e-08 0.30
NU1M_BOVIN MT-ND1 NADH-ubiquinone oxidoreductase chain 1 7.281e-08 0.30
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 7.465e-08 0.38
LUCI_AQULA Luciferin 4-monooxygenase 7.548e-08 0.40
ITA5_HUMAN ITGA5 Integrin alpha-5 8.53e-08 0.42
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 1.266e-07 0.28
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 1.304e-07 0.37
CYNT_HELPY cynT Carbonic anhydrase 1.544e-07 0.33
NEP_RABIT MME Neprilysin 1.693e-07 0.37
PARG_RAT Parg Poly(ADP-ribose) glycohydrolase 2.362e-07 0.29
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 2.422e-07 0.38
LPXC_ECOLI lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 2.47e-07 0.42
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 3.67e-07 0.37
TRY1_HUMAN PRSS1 Trypsin-1 3.711e-07 0.43
EST1_RABIT Liver carboxylesterase 1 5.035e-07 0.32
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 5.378e-07 0.31
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 6.624e-07 0.37
SC6A9_HUMAN SLC6A9 Sodium- and chloride-dependent glycine transporter 1 6.888e-07 0.40
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 1.274e-06 0.59
O77240_CHOFU EcR Ecdysone receptor isoform A 1.277e-06 0.29
LDLR_HUMAN LDLR Low-density lipoprotein receptor 1.285e-06 0.30
A0A060INS8_CAPHI CTSH Cathepsin H 1.64e-06 0.41
5NTD_HUMAN NT5E 5'-nucleotidase 2.184e-06 0.30
NEUR3_HUMAN NEU3 Sialidase-3 2.473e-06 0.29
HDAC1_RAT Hdac1 Histone deacetylase 1 2.726e-06 0.30
PRIO_SHEEP PRNP Major prion protein 2.849e-06 0.29
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.849e-06 0.29
ACRO_PIG ACR Acrosin 3.165e-06 0.30
C3SLB7_ECOLX glmU Bifunctional protein GlmU 5.091e-06 0.28
A5H660_SCHMA HDAC8 Histone deacetylase 8 5.79e-06 0.33
AMPL_PIG LAP3 Cytosol aminopeptidase 8.819e-06 0.31

Clozapine

DRD2_RAT Drd2 D(2) dopamine receptor 1.264e-29 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 3.479e-08 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 5.986e-77 0.66
HRH4_HUMAN HRH4 Histamine H4 receptor 8.85e-67 0.78
DRD1_RAT Drd1 D(1A) dopamine receptor 4.152e-48 0.76
HRH4_RAT Hrh4 Histamine H4 receptor 1.444e-42 0.37
PRIO_MOUSE Prnp Major prion protein 6.694e-38 0.30
DRD2_HUMAN DRD2 D(2) dopamine receptor 5.269e-31 0.74
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.226e-31 0.76
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.923e-26 0.76
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 1.112e-25 0.37
HRH1_RAT Hrh1 Histamine H1 receptor 5.971e-23 0.62
DRD4_HUMAN DRD4 D(4) dopamine receptor 7.224e-21 0.74
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.974e-20 0.65
Q39829_SOYBN Lipoxygenase 2.755e-20 0.32
DRD5_HUMAN DRD5 D(1B) dopamine receptor 7.98e-20 0.60
Q91ZY3_CAVPO HRH4 Histamine H4 receptor 6.741e-19 0.30
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 2.117e-18 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 4.142e-18 0.30
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 4.32e-18 0.35
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 2.22e-16 0.35
KAPCA_RAT Prkaca cAMP-dependent protein kinase catalytic subunit alpha 4.441e-16 0.31
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 2.884e-13 0.35
KCNH2_CAVPO KCNH2 Potassium voltage-gated channel subfamily H member 2 3.14e-13 0.31
DRD4_RAT Drd4 D(4) dopamine receptor 8.372e-13 0.49
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.381e-12 0.55
HRH4_MOUSE Hrh4 Histamine H4 receptor 4.509e-12 0.32
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.011e-11 0.76
CALM_BOVIN CALM Calmodulin 3.542e-11 0.30
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.052e-10 0.35
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 3.387e-10 0.42
KPCL_HUMAN PRKCH Protein kinase C eta type 9.519e-10 0.35
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.722e-09 0.42
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 1.782e-09 0.31
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 6.95e-09 0.30
HRH1_HUMAN HRH1 Histamine H1 receptor 7.167e-09 0.62
CALM1_HUMAN CALM1 Calmodulin-1 1.709e-08 0.30
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 1.881e-08 0.33
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 3.167e-08 0.32
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 3.77e-08 0.37
DRD3_RAT Drd3 D(3) dopamine receptor 3.986e-08 0.39
5HT3A_MOUSE Htr3a 5-hydroxytryptamine receptor 3A 4.352e-08 0.30
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 4.927e-08 0.37
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 6.851e-08 0.56
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 8.367e-08 0.32
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 8.843e-08 0.32
KCNQ1_CAVPO KCNQ1 Potassium voltage-gated channel subfamily KQT member 1 1.237e-07 0.31
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.266e-07 0.42
TYTR_TRYBB TPR Trypanothione reductase 1.59e-07 0.36
KPCE_HUMAN PRKCE Protein kinase C epsilon type 2.788e-07 0.35
TAT_HV112 tat Protein Tat 1.09e-06 0.30
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 1.732e-06 0.33
ABCC8_RAT Abcc8 ATP-binding cassette sub-family C member 8 1.88e-06 0.28
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.941e-06 0.34
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 2.411e-06 0.42
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.5e-06 0.56
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 2.558e-06 0.29
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 2.712e-06 0.33
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 3.186e-06 0.31
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 3.398e-06 0.42
KPCB_HUMAN PRKCB Protein kinase C beta type 3.493e-06 0.35
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 5.034e-06 0.35
DRD3_HUMAN DRD3 D(3) dopamine receptor 5.596e-06 0.63
CNR2_RAT Cnr2 Cannabinoid receptor 2 6.964e-06 0.34
HRH2_HUMAN HRH2 Histamine H2 receptor 7.369e-06 0.58
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 8.822e-06 0.30
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 9.733e-06 0.56

Floxuridine

TYSY_MOUSE Tyms Thymidylate synthase 1.938e-29 1.00
STRP_STRP1 ska Streptokinase A 0.905 1.00
A3RLP8_CHV1 UL23 Thymidine kinase 3.774e-124 0.74
TYSY_LACCA thyA Thymidylate synthase 1.389e-121 0.72
THYX_MYCTU thyX Flavin-dependent thymidylate synthase 1.431e-117 0.71
KTHY_MYCTU tmk Thymidylate kinase 1.396e-107 0.73
CDD_HUMAN CDA Cytidine deaminase 2.595e-106 0.36
KITH_HUMAN TK1 Thymidine kinase, cytosolic 4.576e-102 0.74
KITM_HUMAN TK2 Thymidine kinase 2, mitochondrial 3.009e-99 0.50
KITH_VZVD TK Thymidine kinase 2.779e-95 0.41
KITH_HHV1S TK Thymidine kinase 3.688e-89 0.74
TYSY_MYCTU thyA Thymidylate synthase ThyA 2.8e-88 0.71
DNK_DROME dnk Deoxynucleoside kinase 2.885e-84 0.47
KITH_RAT Tk1 Thymidine kinase, cytosolic 8.587e-80 0.58
CDD_MOUSE Cda Cytidine deaminase 1.038e-68 0.33
TYSY_BOVIN TYMS Thymidylate synthase 2.92e-68 0.43
TYPH_RAT Tymp Thymidine phosphorylase 4.116e-64 0.37
D3ZGQ2_RAT Tk2 Thymidine kinase 2 1.17e-63 0.51
KTHY_HUMAN DTYMK Thymidylate kinase 4.816e-59 0.35
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 2.091e-54 0.38
Q6L709_HHV2 TK Thymidine kinase 1.631e-52 0.50
DPOD1_HUMAN POLD1 DNA polymerase delta catalytic subunit 7.095e-50 0.40
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 2.353e-38 0.43
KITH_HHV1 TK Thymidine kinase 3.56e-38 0.47
NT5M_HUMAN NT5M 5'(3')-deoxyribonucleotidase, mitochondrial 1.443e-37 0.30
GGTA1_BOVIN GGTA1 N-acetyllactosaminide alpha-1,3-galactosyltransferase 1.71e-35 0.28
Q8KHJ3_NEIME lgtC Alpha 1,4 galactosyltransferase 1.71e-35 0.28
Q8II92_PLAF7 Deoxyuridine 5'-triphosphate nucleotidohydrolase 1.336e-30 0.39
P2RY6_HUMAN P2RY6 P2Y purinoceptor 6 1.8e-30 0.47
UMPS_HUMAN UMPS Uridine 5'-monophosphate synthase 5.491e-30 0.30
KITH_VZVO TK Thymidine kinase 1.068e-29 0.37
DPOLB_HUMAN POLB DNA polymerase beta 1.704e-28 0.47
ADOK_MYCTO adoK Adenosine kinase 1.539e-27 0.32
P2RY2_HUMAN P2RY2 P2Y purinoceptor 2 3.231e-26 0.47
PYRF_METTH pyrF Orotidine 5'-phosphate decarboxylase 4.369e-26 0.37
RNAS1_HUMAN RNASE1 Ribonuclease pancreatic 8.912e-26 0.32
RNAS2_HUMAN RNASE2 Non-secretory ribonuclease 8.912e-26 0.32
DPOL_HHV1K DNA polymerase catalytic subunit 9.742e-25 0.40
ADA_MOUSE Ada Adenosine deaminase 1.114e-23 0.29
DPOL_HHV11 DNA polymerase catalytic subunit 6.247e-18 0.40
DPOL_VZVD DNA polymerase catalytic subunit 6.247e-18 0.40
PYRF_YEAST URA3 Orotidine 5'-phosphate decarboxylase 1.11e-16 0.32
ADCY5_RAT Adcy5 Adenylate cyclase type 5 4.108e-15 0.42
P2RY6_RAT P2ry6 P2Y purinoceptor 6 5.884e-15 0.33
B4GT1_BOVIN B4GALT1 Beta-1,4-galactosyltransferase 1 8.105e-15 0.28
ADA_BOVIN ADA Adenosine deaminase 8.993e-15 0.40
P2RY4_HUMAN P2RY4 P2Y purinoceptor 4 1.121e-14 0.47
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 4.308e-14 0.43
TYSY_HUMAN TYMS Thymidylate synthase 8.771e-14 0.71
Q72547_9HIV1 pol Reverse transcriptase/RNaseH 1.141e-13 0.62
Q03732_HBV HBcAg Capsid protein 2.842e-13 0.74
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 1.125e-12 0.63
ITPR1_RAT Itpr1 Inositol 1,4,5-trisphosphate receptor type 1 5.371e-11 0.32
TYPH_HUMAN TYMP Thymidine phosphorylase 2.908e-10 0.46
Q9WKE8_9HIV1 reverse transcriptase Reverse transcriptase 4.689e-10 0.54
P2Y14_HUMAN P2RY14 P2Y purinoceptor 14 3.805e-09 0.33
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 7.85e-09 0.44
ASAH1_RAT Asah1 Acid ceramidase 1.81e-08 0.31
Q9WJQ2_9HIV1 reverse transcriptase Reverse transcriptase protein 6.255e-08 0.54
GRIK5_HUMAN GRIK5 Glutamate receptor ionotropic, kainate 5 1.223e-06 0.34
C3SWJ7_ECOLX thyA Thymidylate synthase 1.272e-06 0.71
GRIA4_RAT Gria4 Glutamate receptor 4 2.838e-06 0.34

Cetirizine

HRH1_HUMAN HRH1 Histamine H1 receptor 5.095e-28 1.00
CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 4.958e-110 0.55
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 3.196e-98 0.55
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 2.435e-90 0.55
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 2.435e-90 0.55
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 9.472e-82 0.55
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 8.033e-70 0.53
DRD4_RAT Drd4 D(4) dopamine receptor 1.273e-69 0.40
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.581e-61 0.43
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.706e-52 0.45
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 1.936e-51 0.55
SC6A1_RAT Slc6a1 Sodium- and chloride-dependent GABA transporter 1 5.371e-49 0.41
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.653e-47 0.39
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 5.484e-46 0.34
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 4.867e-44 0.39
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 4.162e-42 0.44
DRD4_HUMAN DRD4 D(4) dopamine receptor 5.12e-41 0.44
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.541e-40 0.74
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 8.295e-37 0.40
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 1.415e-36 0.55
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.144e-35 0.37
O19067_PIG N-methyl-D-aspartate receptor 1.377e-35 0.28
TYRP1_MOUSE Tyrp1 5,6-dihydroxyindole-2-carboxylic acid oxidase 4.217e-35 0.29
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 2.006e-34 0.45
DRD3_HUMAN DRD3 D(3) dopamine receptor 2.471e-34 0.62
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 4.274e-33 0.55
OPRX_HUMAN OPRL1 Nociceptin receptor 6.238e-32 0.46
NK2R_BOVIN TACR2 Substance-K receptor 5.36e-31 0.31
HRH3_CAVPO HRH3 Histamine H3 receptor 1.042e-30 0.36
PI2R_HUMAN PTGIR Prostacyclin receptor 1.677e-30 0.41
US28_HCMVA US28 G-protein coupled receptor homolog US28 5.397e-27 0.40
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.757e-26 0.41
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 3.404e-25 0.40
TYTR_TRYBB TPR Trypanothione reductase 1.157e-24 0.34
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 8.657e-24 0.29
ZN664_CAVPO ZNF664 Zinc finger protein 664 1.926e-23 0.29
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 2.058e-23 0.43
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 3.945e-23 0.43
DRD5_HUMAN DRD5 D(1B) dopamine receptor 4.042e-23 0.35
PCP_HUMAN PRCP Lysosomal Pro-X carboxypeptidase 4.877e-23 0.40
Q63380_RAT NET Transporter 2.078e-22 0.36
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 2.463e-22 0.41
OPRD_HUMAN OPRD1 Delta-type opioid receptor 5.456e-22 0.50
HRH1_CAVPO HRH1 Histamine H1 receptor 1.005e-21 0.42
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 2.925e-21 0.74
Q56D28_CAVPO CRTH2 Chemoattractant receptor-homologous molecule expressed on Th2 cells 3.935e-21 0.36
HRH2_HUMAN HRH2 Histamine H2 receptor 4.225e-20 0.35
MGLL_MOUSE Mgll Monoglyceride lipase 5.447e-20 0.43
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 1.97e-19 0.40
SC6A1_MOUSE Slc6a1 Sodium- and chloride-dependent GABA transporter 1 2.63e-19 0.38
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.397e-19 0.41
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 1.883e-18 0.32
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 3.586e-18 0.74
DRD1_PIG DRD1 D(1A) dopamine receptor 1.11e-16 0.32
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.11e-16 0.48
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.11e-16 0.36
PI2R_RAT Ptgir Prostacyclin receptor 3.331e-16 0.35
PA_I000X PA Polymerase acidic protein 6.661e-16 0.30
Q9WTR4_RAT Slc6a2 Transporter 3.331e-15 0.38
H10_HUMAN H1-0 Histone H1.0 3.442e-15 0.29
HRH3_HUMAN HRH3 Histamine H3 receptor 4.663e-15 0.36
MGLL_RAT Mgll Monoglyceride lipase 5.107e-15 0.36
LKHA4_HUMAN LTA4H Leukotriene A-4 hydrolase 5.884e-15 0.38
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.166e-14 0.36
DRD1_HUMAN DRD1 D(1A) dopamine receptor 2.331e-14 0.37
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.398e-14 0.46
DRD2_RAT Drd2 D(2) dopamine receptor 4.607e-14 0.38
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 5.596e-14 0.40
NK2R_RAT Tacr2 Substance-K receptor 1.458e-13 0.31
SL9A3_RAT Slc9a3 Sodium/hydrogen exchanger 3 1.472e-13 0.30
ACES_ELEEL ache Acetylcholinesterase 2.034e-13 0.43
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 3.11e-13 0.55
NK2R_HUMAN TACR2 Substance-K receptor 8.368e-13 0.32
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 8.444e-13 0.31
MAP11_HUMAN METAP1 Methionine aminopeptidase 1 1.112e-12 0.30
DRD3_RAT Drd3 D(3) dopamine receptor 1.705e-12 0.33
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 1.832e-12 0.30
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 2.162e-12 0.30
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.779e-12 0.36
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.336e-12 0.41
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 5.806e-12 0.55
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 6.161e-12 0.32
CNR1_RAT Cnr1 Cannabinoid receptor 1 6.543e-12 0.43
CD69_HUMAN CD69 Early activation antigen CD69 7.616e-12 0.29
CNR1_HUMAN CNR1 Cannabinoid receptor 1 7.791e-12 0.43
TRPM2_HUMAN TRPM2 Transient receptor potential cation channel subfamily M member 2 8.017e-12 0.29
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 8.629e-12 0.39
MC4R_HUMAN MC4R Melanocortin receptor 4 1.287e-11 0.40
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.388e-11 0.36
CALM_BOVIN CALM Calmodulin 1.754e-11 0.31
EBP_CAVPO EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 3.343e-11 0.32
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 7.435e-11 0.32
MGLL_HUMAN MGLL Monoglyceride lipase 9.299e-11 0.36
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.43e-10 0.42
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 1.554e-10 0.41
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.011e-10 0.32
O31048_PORGN DPP IV Dipeptidyl peptidase IV 2.055e-10 0.48
KCNA5_HUMAN KCNA5 Potassium voltage-gated channel subfamily A member 5 2.57e-10 0.45
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.561e-10 0.36
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 4.2e-10 0.43
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 4.942e-10 0.34
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 5.725e-10 0.52
NOS2_MOUSE Nos2 Nitric oxide synthase, inducible 8.26e-10 0.32
ADA1B_HUMAN ADRA1B Alpha-1B adrenergic receptor 9.369e-10 0.48
SC6A1_HUMAN SLC6A1 Sodium- and chloride-dependent GABA transporter 1 9.404e-10 0.32
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.185e-09 0.40
GABR2_RAT Gabbr2 Gamma-aminobutyric acid type B receptor subunit 2 1.547e-09 0.33
MCHR1_RAT Mchr1 Melanin-concentrating hormone receptor 1 2.231e-09 0.32
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.108e-09 0.29
O31272_9GAMM imiS Beta-lactamase 3.598e-09 0.29
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 3.749e-09 0.30
5HT4R_RAT Htr4 5-hydroxytryptamine receptor 4 5.767e-09 0.38
MRP2_HUMAN ABCC2 Canalicular multispecific organic anion transporter 1 7.167e-09 0.33
AP2S1_RAT Ap2s1 AP-2 complex subunit sigma 1.153e-08 0.29
Q6L5J4_HUMAN FPRL2 FML2_HUMAN 1.253e-08 0.32
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 1.613e-08 0.32
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 1.641e-08 0.41
MEP50_HUMAN WDR77 Methylosome protein 50 1.908e-08 0.34
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 2.331e-08 0.34
NK1R_HUMAN TACR1 Substance-P receptor 2.487e-08 0.51
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 3.217e-08 0.39
DRD3_CHLAE DRD3 D(3) dopamine receptor 3.505e-08 0.29
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 3.548e-08 0.29
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 4.755e-08 0.29
OPRD_RAT Oprd1 Delta-type opioid receptor 7.79e-08 0.50
RCE1_YEAST RCE1 CAAX prenyl protease 2 1.203e-07 0.41
5HT1A_MOUSE Htr1a 5-hydroxytryptamine receptor 1A 1.64e-07 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.729e-07 0.41
CASR_HUMAN CASR Extracellular calcium-sensing receptor 2.156e-07 0.33
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.406e-07 0.40
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 2.407e-07 0.36
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 2.455e-07 0.37
PA_I34A1 PA Polymerase acidic protein 2.471e-07 0.30
FABP4_HUMAN FABP4 Fatty acid-binding protein, adipocyte 3.151e-07 0.31
GABR1_RAT Gabbr1 Gamma-aminobutyric acid type B receptor subunit 1 4.324e-07 0.33
DRD2_MOUSE Drd2 D(2) dopamine receptor 4.598e-07 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 6.622e-07 0.30
GABR2_HUMAN GABBR2 Gamma-aminobutyric acid type B receptor subunit 2 7.828e-07 0.33
GP183_HUMAN GPR183 G-protein coupled receptor 183 7.94e-07 0.34
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 1.09e-06 0.30
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.203e-06 0.31
GABR1_HUMAN GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 1.288e-06 0.33
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.656e-06 0.31
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.659e-06 0.41
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 1.692e-06 0.32
ACM1_RAT Chrm1 Muscarinic acetylcholine receptor M1 1.736e-06 0.33
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.905e-06 0.32
SL9A3_HUMAN SLC9A3 Sodium/hydrogen exchanger 3 2.094e-06 0.30
PPARA_HUMAN PPARA Peroxisome proliferator-activated receptor alpha 2.112e-06 0.33
SENP1_HUMAN SENP1 Sentrin-specific protease 1 2.32e-06 0.29
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.474e-06 0.41
ACHP_LYMST Acetylcholine-binding protein 2.476e-06 0.34
GP183_MOUSE Gpr183 G-protein coupled receptor 183 2.907e-06 0.34
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 2.948e-06 0.40
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 3.432e-06 0.30
5HT4R_HUMAN HTR4 5-hydroxytryptamine receptor 4 4.032e-06 0.32
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 4.295e-06 0.36
HCN1_HUMAN HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 7.581e-06 0.29

Profenamine

CHLE_HUMAN BCHE Cholinesterase 2.08e-25 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.86e-10 1.00
CHLE_HORSE BCHE Cholinesterase 1.018e-05 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.003097 1.00
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 0.005635 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 6.588e-113 0.47
PRIO_MOUSE Prnp Major prion protein 1.005e-49 0.40
TYTR_TRYCR TPR Trypanothione reductase 1.308e-31 0.40
LYSC1_RAT Lyz1 Lysozyme C-1 4.502e-26 0.32
ITAM_HUMAN ITGAM Integrin alpha-M 1.246e-25 0.32
CALM_BOVIN CALM Calmodulin 1.314e-25 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 5.289e-21 0.40
BGLR_RAT Gusb Beta-glucuronidase 3.462e-20 0.32
EBPL_HUMAN EBPL Emopamil-binding protein-like 3.462e-20 0.32
CALM1_HUMAN CALM1 Calmodulin-1 3.113e-19 0.40
NOX1_HUMAN NOX1 NADPH oxidase 1 1.167e-17 0.38
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 5.662e-15 0.31
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 2.144e-13 0.37
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.601e-11 0.37
DEF_STAAM def Peptide deformylase 7.996e-11 0.30
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.64e-10 0.74
HRH2_HUMAN HRH2 Histamine H2 receptor 4.079e-09 0.74
PRIO_HUMAN PRNP Major prion protein 6.987e-09 0.74
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 2.134e-07 0.40
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 5.799e-07 0.33
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 8.574e-07 0.74
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 5.639e-06 0.40
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 6.224e-06 0.31
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 8.866e-06 0.74

Mirtazapine

DRD1_RAT Drd1 D(1A) dopamine receptor 1.186e-21 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 4.186e-14 1.00
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 3.438e-13 1.00
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 1.036e-12 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.391e-08 1.00
DRD2_RAT Drd2 D(2) dopamine receptor 4.391e-08 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 6.139e-07 1.00
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 2.653e-06 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 9.936e-06 1.00
Q9WTR4_RAT Slc6a2 Transporter 6.929e-05 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.0002206 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.0002425 1.00
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 0.0008896 1.00
ADA1A_HUMAN ADRA1A Alpha-1A adrenergic receptor 0.00103 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.003901 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.009293 1.00
5HT7R_HUMAN HTR7 5-hydroxytryptamine receptor 7 0.07051 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.8854 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.9945 1.00
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 2.911e-21 0.43
HRH1_RAT Hrh1 Histamine H1 receptor 1.109e-19 0.38
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 1.11e-16 0.32
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 2.22e-16 0.43
HRH4_HUMAN HRH4 Histamine H4 receptor 7.772e-16 0.37
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.998e-15 0.42
Q9IP65_HCMV US28 G protein-coupled receptor 5.884e-15 0.28
DRD5_HUMAN DRD5 D(1B) dopamine receptor 8.882e-15 0.36
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 1.099e-14 0.34
5HT3A_RAT Htr3a 5-hydroxytryptamine receptor 3A 3.231e-14 0.42
5HT2A_BOVIN HTR2A 5-hydroxytryptamine receptor 2A 4.964e-11 0.37
US28_HCMVA US28 G-protein coupled receptor homolog US28 1.336e-10 0.28
5HT3B_RAT Htr3b 5-hydroxytryptamine receptor 3B 7.705e-10 0.32
5HT2C_MOUSE Htr2c 5-hydroxytryptamine receptor 2C 2.663e-09 0.31
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.096e-08 0.55
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 3.244e-08 0.32
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 3.464e-08 0.38
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.712e-08 0.36
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 5.031e-08 0.28
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.548e-07 0.38
5HT1D_PIG HTR1D 5-hydroxytryptamine receptor 1D 3.552e-07 0.37
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.928e-07 0.42
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 9.402e-07 0.34
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 9.454e-07 0.39
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.22e-06 0.36
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.743e-06 0.28
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 4.494e-06 0.42
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 4.647e-06 0.35
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 4.759e-06 0.39
DRD3_RAT Drd3 D(3) dopamine receptor 7.313e-06 0.37
HRH4_RAT Hrh4 Histamine H4 receptor 7.483e-06 0.31
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 8.419e-06 0.31
DRD2_HUMAN DRD2 D(2) dopamine receptor 8.801e-06 0.39
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 8.86e-06 0.35

Aminoglutethimide

CP19A_HUMAN CYP19A1 Aromatase 5.297e-21 1.00
CP19A_RAT Cyp19a1 Aromatase 1.96e-07 1.00

Amitriptyline

HRH1_RAT Hrh1 Histamine H1 receptor 4.016e-20 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 8.138e-14 1.00
DRD5_HUMAN DRD5 D(1B) dopamine receptor 6.857e-10 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.187e-09 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 7.175e-09 1.00
SCN2A_HUMAN SCN2A Sodium channel protein type 2 subunit alpha 7.806e-07 1.00
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 1.851e-06 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 1.958e-06 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.442e-05 1.00
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.457e-05 1.00
HRH2_CAVPO HRH2 Histamine H2 receptor 1.71e-05 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 4.686e-05 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 0.0001263 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 0.0002051 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 0.0006876 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 0.001409 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.001581 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 0.003156 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.008205 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 0.009467 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.01027 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 0.01416 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.02019 1.00
SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.02632 1.00
Q9WTR4_RAT Slc6a2 Transporter 0.04978 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0599 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 0.06681 1.00
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 0.09252 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 0.09468 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.1756 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.1962 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.2137 1.00
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 0.4961 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.536 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.6411 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.6628 1.00
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 0.7805 1.00
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 0.9999 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 6.106e-23 0.60
ASM_HUMAN SMPD1 Sphingomyelin phosphodiesterase 5.699e-22 0.55
GAG_AVIER gag Gag polyprotein 7.264e-21 0.33
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.11e-16 0.42
ENV_MMTVG env Envelope glycoprotein gp70 6.661e-16 0.29
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 4.727e-11 0.51
CALM_BOVIN CALM Calmodulin 1.105e-10 0.29
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.706e-09 0.35
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 2.644e-08 0.33
CALM1_HUMAN CALM1 Calmodulin-1 3.985e-08 0.29
TYTR_TRYCR TPR Trypanothione reductase 1.689e-07 0.34
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.866e-06 0.34
NR1I3_HUMAN NR1I3 Nuclear receptor subfamily 1 group I member 3 2.109e-06 0.30
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 2.849e-06 0.29

Triamterene

PTR1_LEIMA PTR1 Pteridine reductase 1 1.299e-19 1.00
CATG_HUMAN CTSG Cathepsin G 3.347e-06 1.00
CASP1_HUMAN CASP1 Caspase-1 0.03466 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.4243 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.7197 1.00
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 0.9955 1.00
TRPM6_HUMAN TRPM6 Transient receptor potential cation channel subfamily M member 6 2.572e-72 0.58
NOS3_PIG NOS3 Nitric oxide synthase, endothelial 1.381e-47 0.35
DRTS_TOXGO Bifunctional dihydrofolate reductase-thymidylate synthase 1.719e-47 0.86
DYR_PNECA Dihydrofolate reductase 1e-46 0.43
DYR_RAT Dhfr Dihydrofolate reductase 3.242e-45 0.43
DYR_YEAST DFR1 Dihydrofolate reductase 1.994e-39 0.39
DYR_MYCTU folA Dihydrofolate reductase 4.566e-28 0.49
PERE_HUMAN EPX Eosinophil peroxidase 1.941e-26 0.33
PERE_MOUSE Epx Eosinophil peroxidase 1.941e-26 0.33
DYR_HUMAN DHFR Dihydrofolate reductase 2.335e-26 0.49
BLAB_SERMA Metallo-beta-lactamase type 2 3.865e-25 0.31
DYR_CANAX DFR1 Dihydrofolate reductase 3.603e-24 0.35
DYR_STAAU folA Dihydrofolate reductase 1.634e-22 0.41
Q81R22_BACAN dfrA Dihydrofolate reductase 3.35e-20 0.31
J7IFZ2_STRPY Dihydrofolate reductase 3.857e-19 0.31
MECP2_HUMAN MECP2 Methyl-CpG-binding protein 2 1.858e-18 0.29
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 4.879e-18 0.29
DYR_MOUSE Dhfr Dihydrofolate reductase 6.927e-18 0.30
DYR_ECOLI folA Dihydrofolate reductase 1.443e-15 0.38
DYR_LACCA folA Dihydrofolate reductase 5.107e-15 0.38
COQ8A_HUMAN COQ8A Atypical kinase COQ8A, mitochondrial 7.661e-15 0.58
OXSR1_HUMAN OXSR1 Serine/threonine-protein kinase OSR1 7.661e-15 0.58
O30463_MYCAV folA Dihydrofolate reductase 1.676e-14 0.43
KC1AL_HUMAN CSNK1A1L Casein kinase I isoform alpha-like 4.041e-14 0.58
AHR_MOUSE Ahr Aryl hydrocarbon receptor 1.174e-13 0.30
COQ8B_HUMAN COQ8B Atypical kinase COQ8B, mitochondrial 1.754e-13 0.58
PI51C_HUMAN PIP5K1C Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 1.754e-13 0.58
AA1R_HUMAN ADORA1 Adenosine receptor A1 1.902e-13 0.44
ADK_RAT Adk Adenosine kinase 8.571e-13 0.42
LATS1_HUMAN LATS1 Serine/threonine-protein kinase LATS1 2.081e-12 0.58
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 5.976e-12 0.58
GUAD_HUMAN GDA Guanine deaminase 1.007e-11 0.32
AA2AR_HUMAN ADORA2A Adenosine receptor A2a 1.36e-11 0.44
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 1.557e-11 0.58
RIPK4_HUMAN RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1.557e-11 0.58
DNLJ_STAAU ligA DNA ligase 4.899e-11 0.38
LATS2_HUMAN LATS2 Serine/threonine-protein kinase LATS2 8.317e-11 0.58
PI42B_HUMAN PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 8.317e-11 0.58
PI51A_HUMAN PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 3.446e-10 0.58
B0BL08_ECOLX dfrA17 Dihydrofolate reductase 3.706e-10 0.45
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 1.036e-09 0.33
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 1.045e-09 0.28
RIOK1_HUMAN RIOK1 Serine/threonine-protein kinase RIO1 1.172e-09 0.58
RIOK2_HUMAN RIOK2 Serine/threonine-protein kinase RIO2 1.172e-09 0.58
MGMT_HUMAN MGMT Methylated-DNA--protein-cysteine methyltransferase 1.226e-09 0.33
DCPS_HUMAN DCPS m7GpppX diphosphatase 1.384e-09 0.41
SRPK3_HUMAN SRPK3 SRSF protein kinase 3 2.034e-09 0.58
GRK4_HUMAN GRK4 G protein-coupled receptor kinase 4 3.409e-09 0.58
MK01_RAT Mapk1 Mitogen-activated protein kinase 1 7.576e-09 0.31
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 8.736e-09 0.58
Q8Z9J9_SALTI folA Dihydrofolate reductase 1.027e-08 0.35
MP2K4_HUMAN MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 1.344e-08 0.58
BMP2K_HUMAN BMP2K BMP-2-inducible protein kinase 2.966e-08 0.58
KS6A6_HUMAN RPS6KA6 Ribosomal protein S6 kinase alpha-6 2.966e-08 0.58
STK16_HUMAN STK16 Serine/threonine-protein kinase 16 4.275e-08 0.58
DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 1.213e-07 0.37
EPHA4_MOUSE Epha4 Ephrin type-A receptor 4 8.207e-07 0.29
AAK1_HUMAN AAK1 AP2-associated protein kinase 1 9.226e-07 0.58
Q9K2N0_PSEAI blaVIM-2 Beta-lactamase class B VIM-2 9.855e-07 0.31
XDH_HUMAN XDH Xanthine dehydrogenase/oxidase 1.832e-06 0.34
TYSY_LACCA thyA Thymidylate synthase 2.04e-06 0.38
P3C2B_HUMAN PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 3.601e-06 0.58

Promazine

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 4.913e-19 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.251e-18 1.00
HRH1_HUMAN HRH1 Histamine H1 receptor 1.602e-17 1.00
HRH1_RAT Hrh1 Histamine H1 receptor 4.496e-14 1.00
HRH2_HUMAN HRH2 Histamine H2 receptor 2.18e-13 1.00
PRIO_HUMAN PRNP Major prion protein 1.073e-12 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 8.898e-12 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.796e-10 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 2.168e-10 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.118e-09 1.00
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.584e-09 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.697e-09 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 2.687e-08 1.00
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 8.177e-08 1.00
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 8.721e-07 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.384e-06 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 3.895e-06 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 3.906e-06 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 9.785e-06 1.00
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 9.965e-06 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 3.571e-05 1.00
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 6.316e-05 1.00
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 9.26e-05 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 0.0001031 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.0001263 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.000184 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.0007346 1.00
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 0.002178 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.007755 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 3.12e-161 0.78
PRIO_MOUSE Prnp Major prion protein 1.375e-97 0.78
TYTR_TRYCR TPR Trypanothione reductase 1.206e-53 0.78
CALM_BOVIN CALM Calmodulin 7.937e-43 0.78
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.055e-35 0.78
LYSC1_RAT Lyz1 Lysozyme C-1 1.073e-34 0.43
CALM1_HUMAN CALM1 Calmodulin-1 4.769e-32 0.78
BGLR_RAT Gusb Beta-glucuronidase 8.394e-27 0.43
EBPL_HUMAN EBPL Emopamil-binding protein-like 8.394e-27 0.43
DEF_STAAM def Peptide deformylase 5.722e-26 0.37
CHLE_HUMAN BCHE Cholinesterase 6.387e-26 0.49
DYN2_RAT Dnm2 Dynamin-2 1.486e-25 0.31
ITAM_HUMAN ITGAM Integrin alpha-M 2.962e-24 0.30
DYN2_HUMAN DNM2 Dynamin-2 2.097e-23 0.31
NOX1_HUMAN NOX1 NADPH oxidase 1 9.324e-21 0.39
CAC1S_HUMAN CACNA1S Voltage-dependent L-type calcium channel subunit alpha-1S 7.772e-16 0.38
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 7.772e-16 0.78
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 1.998e-15 0.52
HRH1_CAVPO HRH1 Histamine H1 receptor 2.887e-15 0.78
DEFM_HUMAN PDF Peptide deformylase, mitochondrial 5.329e-15 0.42
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 6.106e-14 0.78
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 7.749e-13 0.39
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 7.968e-13 0.41
MYLK_HUMAN MYLK Myosin light chain kinase, smooth muscle 8.669e-13 0.31
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 4.426e-12 0.52
CDK1_MOUSE Cdk1 Cyclin-dependent kinase 1 5.427e-12 0.29
CHLE_HORSE BCHE Cholinesterase 5.449e-12 0.71
TYTR_TRYBB TPR Trypanothione reductase 2.966e-11 0.52
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 5.842e-10 0.78
DRD5_HUMAN DRD5 D(1B) dopamine receptor 1.008e-09 0.78
ERG2_YEAST ERG2 C-8 sterol isomerase 1.765e-09 0.43
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.863e-09 0.30
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 2.073e-09 0.45
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 8.253e-09 0.35
CNOT7_HUMAN CNOT7 CCR4-NOT transcription complex subunit 7 2.572e-08 0.29
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.062e-08 0.43
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 8.564e-08 0.35
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 9.003e-08 0.35
PABP1_HUMAN PABPC1 Polyadenylate-binding protein 1 4.177e-07 0.36
PERM_HUMAN MPO Myeloperoxidase 8.117e-07 0.35
NMDE1_HUMAN GRIN2A Glutamate receptor ionotropic, NMDA 2A 4.877e-06 0.31
CAC1C_RAT Cacna1c Voltage-dependent L-type calcium channel subunit alpha-1C 6.044e-06 0.34
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 6.29e-06 0.39

Methylergometrine

5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 8.972e-18 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.108e-15 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 2.074e-12 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 1.237e-09 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 3.535e-09 1.00
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 2.382e-06 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 4.286e-06 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 1.164e-05 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.018e-05 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.0002181 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.0008147 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.000841 1.00
CASP6_HUMAN CASP6 Caspase-6 0.01055 1.00
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 2.386e-104 0.55
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 1.341e-84 0.50
DRD1_MOUSE Drd1 D(1A) dopamine receptor 1.101e-31 0.61
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 3.183e-29 0.55
GRP1_RAT Rasgrp1 RAS guanyl-releasing protein 1 2.578e-18 0.35
CARP2_CANAX SAP2 Candidapepsin-2 9.326e-18 0.29
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 1.11e-16 0.61
5HT5A_MOUSE Htr5a 5-hydroxytryptamine receptor 5A 2.709e-14 0.70
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.72e-13 0.91
5HT5A_HUMAN HTR5A 5-hydroxytryptamine receptor 5A 6.828e-12 0.70
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.71e-11 0.59
CLK2_MOUSE Clk2 Dual specificity protein kinase CLK2 5.323e-11 0.29
CLK4_MOUSE Clk4 Dual specificity protein kinase CLK4 5.323e-11 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.043e-08 0.29
CLK3_MOUSE Clk3 Dual specificity protein kinase CLK3 6.963e-08 0.28
CLK1_MOUSE Clk1 Dual specificity protein kinase CLK1 1.525e-07 0.29
SSR2_RAT Sstr2 Somatostatin receptor type 2 3.862e-07 0.33
DRD5_HUMAN DRD5 D(1B) dopamine receptor 3.942e-07 0.61
PLEC_HUMAN PLEC Plectin 8.743e-07 0.68
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 1.103e-06 0.59
DYRK2_HUMAN DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1.107e-06 0.29
SSR1_RAT Sstr1 Somatostatin receptor type 1 2.468e-06 0.33
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 7.603e-06 0.59

Dihydroergotamine

ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 1.11e-16 1.00
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 8.882e-16 1.00
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 2.22e-15 1.00
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 5.316e-11 1.00
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.81e-09 1.00
ADA2C_HUMAN ADRA2C Alpha-2C adrenergic receptor 8.506e-09 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 1.998e-08 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 2.826e-08 1.00
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 5.779e-08 1.00
5HT4R_CAVPO HTR4 5-hydroxytryptamine receptor 4 5.535e-07 1.00
ADA1D_HUMAN ADRA1D Alpha-1D adrenergic receptor 5.707e-05 1.00
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 6.405e-05 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 9.646e-05 1.00
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 0.001028 1.00
DRD2_HUMAN DRD2 D(2) dopamine receptor 0.003013 1.00
5HT2C_HUMAN HTR2C 5-hydroxytryptamine receptor 2C 0.004191 1.00
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.007733 1.00
DRD3_HUMAN DRD3 D(3) dopamine receptor 0.0112 1.00
5HT2A_HUMAN HTR2A 5-hydroxytryptamine receptor 2A 0.01615 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.2613 1.00
SSR1_RAT Sstr1 Somatostatin receptor type 1 1.548e-46 0.43
SSR2_RAT Sstr2 Somatostatin receptor type 2 4.885e-44 0.43
CXCR3_MOUSE Cxcr3 C-X-C chemokine receptor type 3 1.125e-31 0.30
CXCR3_RAT Cxcr3 C-X-C chemokine receptor type 3 5.46e-30 0.30
DRD1_MOUSE Drd1 D(1A) dopamine receptor 4.108e-15 0.28
OXYR_RAT Oxtr Oxytocin receptor 9.659e-15 0.32
AGRA_STAAU agrA Accessory gene regulator protein A 3.471e-13 0.32
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 5.597e-12 0.30
AT2A1_HUMAN ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 1.02e-10 0.31
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 4e-10 0.32
EDNRA_PIG EDNRA Endothelin-1 receptor 7.301e-10 0.30
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 3.389e-09 0.32
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 4.233e-09 0.31
V2R_RAT Avpr2 Vasopressin V2 receptor 1.854e-08 0.32
CXCR3_HUMAN CXCR3 C-X-C chemokine receptor type 3 1.922e-08 0.39
5HT1E_HUMAN HTR1E 5-hydroxytryptamine receptor 1E 4.178e-08 0.28
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 8.327e-08 0.32
A0A286XTF2_CAVPO OPRD1 G_PROTEIN_RECEP_F1_2 domain-containing protein 1.041e-07 0.32
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 4.529e-07 0.32
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 5.036e-07 0.38
HDAC1_RAT Hdac1 Histone deacetylase 1 2.488e-06 0.30
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 7.184e-06 0.32

Griseofulvin

S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 4.785e-14 1.00

Eszopiclone

GBRA4_HUMAN GABRA4 Gamma-aminobutyric acid receptor subunit alpha-4 2.504e-10 1.00
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 0.02462 1.00
NPBW1_MOUSE Npbwr1 Neuropeptides B/W receptor type 1 6.084e-51 0.33
S6A15_HUMAN SLC6A15 Sodium-dependent neutral amino acid transporter B(0)AT2 7.049e-38 0.32
HRH1_RAT Hrh1 Histamine H1 receptor 4.36e-23 0.33
SMO_HUMAN SMO Smoothened homolog 7.233e-21 0.38
Q91ZY3_CAVPO HRH4 Histamine H4 receptor 1.523e-18 0.29
CEGT_HUMAN UGCG Ceramide glucosyltransferase 4.441e-16 0.32
HRH3_HUMAN HRH3 Histamine H3 receptor 1.078e-11 0.34
FNTB_HUMAN FNTB Protein farnesyltransferase subunit beta 1.684e-11 0.33
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2.545e-11 0.43
FNTA_HUMAN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 8.69e-11 0.33
MEP2_YEAST MEP2 Ammonium transporter MEP2 2.659e-10 0.30
B9W6M3_CANDC CNA1 Serine/threonine-protein phosphatase 2.536e-08 0.29
ADA10_HUMAN ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 2.498e-07 0.28
NK3R_HUMAN TACR3 Neuromedin-K receptor 6.973e-07 0.32
GYRB_MYCS2 gyrB DNA gyrase subunit B 9.396e-07 0.29
LIPS_HUMAN LIPE Hormone-sensitive lipase 3.26e-06 0.35
AGP1_YEAST AGP1 General amino acid permease AGP1 3.933e-06 0.30
P2Y12_RAT P2ry12 P2Y purinoceptor 12 6.582e-06 0.29
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 7.112e-06 0.29

Phenylpropanolamine

ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 8.391e-10 1.00
ADA2B_RAT Adra2b Alpha-2B adrenergic receptor 3.385e-09 1.00
ADA1A_RAT Adra1a Alpha-1A adrenergic receptor 0.0001121 1.00
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 0.0001659 1.00
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 0.001376 1.00
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 3.171e-47 0.39
ACER2_HUMAN ACER2 Alkaline ceramidase 2 3.737e-47 0.38
KYNU_RAT Kynu Kynureninase 7.528e-39 0.31
AMPB_MOUSE Rnpep Aminopeptidase B 2.435e-37 0.30
AMPL_BOVIN LAP3 Cytosol aminopeptidase 2.435e-37 0.30
SYL_STAA8 leuS Leucine--tRNA ligase 5.351e-37 0.29
CERT_HUMAN CERT1 Ceramide transfer protein 9.362e-36 0.28
LAT1_HUMAN SLC7A5 Large neutral amino acids transporter small subunit 1 1.107e-35 0.29
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.542e-32 0.34
BLAB_BACCE Metallo-beta-lactamase type 2 1.337e-31 0.36
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.602e-31 0.34
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.549e-29 0.44
AOC3_HUMAN AOC3 Membrane primary amine oxidase 3.709e-28 0.57
S22A7_RAT Slc22a7 Solute carrier family 22 member 7 5.245e-27 0.33
SYL_ECOLI leuS Leucine--tRNA ligase 8.089e-24 0.29
MANR_PSEPU mdlA Mandelate racemase 1.139e-23 0.38
AMPB_RAT Rnpep Aminopeptidase B 8.2e-20 0.30
AMPL_HUMAN LAP3 Cytosol aminopeptidase 3.867e-19 0.34
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 7.511e-19 0.31
LCAP_RAT Lnpep Leucyl-cystinyl aminopeptidase 1.265e-18 0.30
VM1B1_BOTAS Snake venom metalloproteinase BaP1 3.143e-18 0.29
PPAP_HUMAN ACP3 Prostatic acid phosphatase 1.937e-17 0.34
VANX_ENTFC vanX D-alanyl-D-alanine dipeptidase 3.987e-17 0.38
DNPEP_HUMAN DNPEP Aspartyl aminopeptidase 3.331e-16 0.31
MA2A1_HUMAN MAN2A1 Alpha-mannosidase 2 6.661e-16 0.30
NEP_MOUSE Mme Neprilysin 1.443e-15 0.34
MA1B1_HUMAN MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1.776e-15 0.30
KYNU_HUMAN KYNU Kynureninase 4.43e-14 0.31
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.063e-14 0.32
AMPN_HUMAN ANPEP Aminopeptidase N 1.135e-13 0.38
ACE_MOUSE Ace Angiotensin-converting enzyme 1.268e-13 0.29
CALM_BOVIN CALM Calmodulin 2.492e-12 0.33
AMPX_VIBPR Bacterial leucyl aminopeptidase 4.114e-12 0.30
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 6.296e-12 0.29
VMAT2_MOUSE Slc18a2 Synaptic vesicular amine transporter 1.437e-11 0.28
PPO1_AGABI PPO1 Polyphenol oxidase 1 3.83e-11 0.35
AMPN_MOUSE Anpep Aminopeptidase N 5.087e-11 0.30
GRIK3_RAT Grik3 Glutamate receptor ionotropic, kainate 3 6.092e-11 0.34
AMPN_PIG ANPEP Aminopeptidase N 7.619e-11 0.41
AMPB_HUMAN RNPEP Aminopeptidase B 1.105e-10 0.29
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.168e-10 0.44
NK1R_RAT Tacr1 Substance-P receptor 1.827e-10 0.36
BLAB_AERHY cphA Metallo-beta-lactamase type 2 5.219e-10 0.31
NPY5R_HUMAN NPY5R Neuropeptide Y receptor type 5 8.596e-10 0.39
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 9.68e-10 0.31
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 1.953e-09 0.50
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 2.428e-09 0.32
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 7.167e-09 0.33
CBPA1_BOVIN CPA1 Carboxypeptidase A1 8.205e-09 0.35
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 8.515e-09 0.29
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.043e-08 0.29
VMAT2_HUMAN SLC18A2 Synaptic vesicular amine transporter 1.324e-07 0.28
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 1.631e-07 0.29
PSA_HUMAN NPEPPS Puromycin-sensitive aminopeptidase 2.996e-07 0.30
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 3.597e-07 0.31
BLA2_BACCE blm Metallo-beta-lactamase type 2 3.68e-07 0.36
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 5.577e-07 0.31
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 5.734e-07 0.29
CBPN_HUMAN CPN1 Carboxypeptidase N catalytic chain 7.834e-07 0.29
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 1.262e-06 0.29
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 1.615e-06 0.41
HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.922e-06 0.33
ACM2_MOUSE Chrm2 Muscarinic acetylcholine receptor M2 2.473e-06 0.29
OXDA_MOUSE Dao D-amino-acid oxidase 2.794e-06 0.30
SYYC_HUMAN YARS1 Tyrosine--tRNA ligase, cytoplasmic 5.455e-06 0.30

Alprazolam

BRD4_HUMAN BRD4 Bromodomain-containing protein 4 1.884e-09 1.00
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 6.36e-08 1.00
GBRA2_HUMAN GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 2.19e-06 1.00
GBRA5_HUMAN GABRA5 Gamma-aminobutyric acid receptor subunit alpha-5 7.578e-06 1.00
GBRA3_HUMAN GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 2.414e-05 1.00
PTAFR_HUMAN PTAFR Platelet-activating factor receptor 1.681e-62 0.62
SC6A9_RAT Slc6a9 Sodium- and chloride-dependent glycine transporter 1 1.153e-42 0.38
SC6A5_RAT Slc6a5 Sodium- and chloride-dependent glycine transporter 2 4.332e-38 0.38
AHR_MOUSE Ahr Aryl hydrocarbon receptor 1.646e-27 0.32
BRD3_HUMAN BRD3 Bromodomain-containing protein 3 5.104e-18 0.48
BRD2_HUMAN BRD2 Bromodomain-containing protein 2 1.11e-16 0.48
AURKA_MOUSE Aurka Aurora kinase A 3.164e-13 0.29
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 6.341e-11 0.37
C11B2_HUMAN CYP11B2 Cytochrome P450 11B2, mitochondrial 4.251e-09 0.38
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 3.66e-08 0.30
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 2.289e-07 0.50
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 8.744e-07 0.31
C11B1_HUMAN CYP11B1 Cytochrome P450 11B1, mitochondrial 9.098e-07 0.38
TAT_HV112 tat Protein Tat 1.09e-06 0.30
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 2.455e-06 0.33
GBRA6_HUMAN GABRA6 Gamma-aminobutyric acid receptor subunit alpha-6 3.543e-06 0.33

Valrubicin

VP16_HHV11 Tegument protein VP16 5.235e-09 1.00
CHIO_HUMAN CHN2 Beta-chimaerin 8.666e-81 0.65
S10A4_HUMAN S100A4 Protein S100-A4 1.749e-71 0.64
FANCF_HUMAN FANCF Fanconi anemia group F protein 8.422e-71 0.57
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 4.555e-40 0.64
1433G_HUMAN YWHAG 14-3-3 protein gamma 8.804e-33 0.64
O40947_HHV8 ORF 73 3.012e-20 0.64
TOP2B_HUMAN TOP2B DNA topoisomerase 2-beta 3.331e-16 0.64
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 2.411e-13 0.64
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 3.927e-07 0.61
CISD1_HUMAN CISD1 CDGSH iron-sulfur domain-containing protein 1 5.269e-06 0.64

Metixene

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.609e-08 1.00
CHLE_HORSE BCHE Cholinesterase 3.138e-07 1.00
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 5.513e-56 0.35
SC6A2_MOUSE Slc6a2 Sodium-dependent noradrenaline transporter 1.769e-47 0.33
ADA1B_MESAU ADRA1B Alpha-1B adrenergic receptor 5.028e-41 0.36
ACH10_RAT Chrna10 Neuronal acetylcholine receptor subunit alpha-10 9.313e-41 0.34
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 7.23e-38 0.33
PRIO_MOUSE Prnp Major prion protein 8.858e-37 0.29
ADA1A_BOVIN ADRA1A Alpha-1A adrenergic receptor 3.932e-34 0.36
LYSC1_RAT Lyz1 Lysozyme C-1 4.036e-26 0.32
CALM_BOVIN CALM Calmodulin 5.327e-22 0.32
BGLR_RAT Gusb Beta-glucuronidase 3.184e-20 0.32
EBPL_HUMAN EBPL Emopamil-binding protein-like 3.184e-20 0.32
ADA1D_RAT Adra1d Alpha-1D adrenergic receptor 1.767e-19 0.36
Q39829_SOYBN Lipoxygenase 1.332e-18 0.30
Q9IP65_HCMV US28 G protein-coupled receptor 4.681e-18 0.35
CALM1_HUMAN CALM1 Calmodulin-1 1.11e-16 0.32
Q9WTR4_RAT Slc6a2 Transporter 4.441e-16 0.33
US28_HCMVA US28 G-protein coupled receptor homolog US28 9.49e-13 0.35
DRD1_RAT Drd1 D(1A) dopamine receptor 9.998e-13 0.39
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 3.522e-12 0.60
HRH1_RAT Hrh1 Histamine H1 receptor 6.58e-12 0.39
HRH1_HUMAN HRH1 Histamine H1 receptor 2.137e-11 0.60
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 5.412e-11 0.35
DRD2_RAT Drd2 D(2) dopamine receptor 2.598e-10 0.40
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 2.533e-09 0.29
DRD3_RAT Drd3 D(3) dopamine receptor 1.107e-08 0.39
TYTR_TRYCR TPR Trypanothione reductase 1.344e-08 0.35
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.139e-08 0.33
MALT1_HUMAN MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 7.725e-08 0.60
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 1.057e-07 0.44
LSS_HUMAN LSS Lanosterol synthase 1.093e-07 0.33
DRD2_BOVIN DRD2 D(2) dopamine receptor 2.193e-07 0.37
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 3.621e-07 0.30
5HT7R_RAT Htr7 5-hydroxytryptamine receptor 7 4.09e-07 0.35
ACM5_RAT Chrm5 Muscarinic acetylcholine receptor M5 4.537e-07 0.33
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.21e-06 0.33
DRD2_HUMAN DRD2 D(2) dopamine receptor 1.284e-06 0.36
ADA2B_HUMAN ADRA2B Alpha-2B adrenergic receptor 1.673e-06 0.60
DRD1_HUMAN DRD1 D(1A) dopamine receptor 3.022e-06 0.35
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 5.494e-06 0.35
ADA2A_BOVIN ADRA2A Alpha-2A adrenergic receptor 6.343e-06 0.33

Carbamoylcholine

ACHB2_HUMAN CHRNB2 Neuronal acetylcholine receptor subunit beta-2 0.0006954 1.00
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 0.0007692 1.00
ACHA4_HUMAN CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 0.001015 1.00
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 0.01305 1.00
BODG_HUMAN BBOX1 Gamma-butyrobetaine dioxygenase 4.219e-15 0.31
ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 4.08e-09 0.30
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 4.08e-09 0.30
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 3.632e-08 0.30
SC5A7_MOUSE Slc5a7 High affinity choline transporter 1 3.431e-07 0.32
Q8VH27_CAVPO GPM2 Muscarinic acetylcholine receptor 6.222e-07 0.41
ACES_BOVIN ACHE Acetylcholinesterase 2.461e-06 0.48
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 7.451e-06 0.30

Sulfadiazine

CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 0.001169 1.00
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.053 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.3019 1.00
S40A1_HUMAN SLC40A1 Solute carrier family 40 member 1 1.228e-66 0.41
QCR7_HUMAN UQCRB Cytochrome b-c1 complex subunit 7 6.245e-64 0.33
BRD4_MOUSE Brd4 Bromodomain-containing protein 4 6.425e-56 0.36
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 1.229e-53 0.36
Q5TU56_ANOGA 1272966 Carbonic anhydrase 2.654e-45 0.51
Q56D22_MACMU HSD11B1 Hydroxysteroid 11-beta dehydrogenase 1 1.389e-44 0.35
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 6.672e-43 0.38
DAPAT_ARATH DAP LL-diaminopimelate aminotransferase, chloroplastic 2.905e-40 0.32
CYNT_HELPY cynT Carbonic anhydrase 1.214e-39 0.46
SYL_STAA8 leuS Leucine--tRNA ligase 1.947e-38 0.30
Q81VW8_BACAN folP Dihydropteroate synthase 6.927e-38 0.44
LN28A_MOUSE Lin28a Protein lin-28 homolog A 2.435e-37 0.30
JHD2C_HUMAN JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 5.351e-37 0.29
Q5U9J1_THAWE ca1 Delta carbonic anhydrase 1.261e-35 0.51
AKT1_MOUSE Akt1 RAC-alpha serine/threonine-protein kinase 1.82e-31 0.30
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.042e-31 0.51
C0IX24_STYPI CA2 Carbonic anhydrase 3.629e-31 0.46
ARY1_HUMAN NAT1 Arylamine N-acetyltransferase 1 1.237e-30 0.33
SMCA4_HUMAN SMARCA4 Transcription activator BRG1 1.426e-30 0.36
MTCA2_MYCTU mtcA2 Carbonic anhydrase 2 3.228e-30 0.46
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 3.384e-30 0.50
B2V8E3_SULSY Carbonate dehydratase 5.63e-30 0.46
B5SU02_STYPI CA Alpha carbonic anhydrase 5.63e-30 0.46
Q31FD6_HYDCU Carbonic anhydrase, alpha family 5.63e-30 0.46
SC5A7_RAT Slc5a7 High affinity choline transporter 1 1.218e-28 0.35
Q388H8_TRYB2 Glycylpeptide N-tetradecanoyltransferase 1.519e-28 0.33
A6YCJ1_9METZ Astrosclerin-3 2.163e-28 0.46
ARY2_MOUSE Nat2 Arylamine N-acetyltransferase 2 4.907e-28 0.33
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 7.894e-28 0.37
CAN_YEAST NCE103 Carbonic anhydrase 6.951e-27 0.46
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.886e-25 0.42
SYL_ECOLI leuS Leucine--tRNA ligase 9.841e-25 0.30
DKK1_HUMAN DKK1 Dickkopf-related protein 1 2.161e-23 0.30
CXCR4_RAT Cxcr4 C-X-C chemokine receptor type 4 7.47e-23 0.35
CAH2_HUMAN CA2 Carbonic anhydrase 2 8.985e-23 0.51
METC_ECOLI metC Cystathionine beta-lyase MetC 9.887e-23 0.33
SCN3A_HUMAN SCN3A Sodium channel protein type 3 subunit alpha 1.393e-22 0.35
Q5XX84_CANLF HSD11B1 11-beta-hydroxysteroid dehydrogenase type 1 3.711e-22 0.35
BRD7_HUMAN BRD7 Bromodomain-containing protein 7 1.615e-21 0.36
CAH_METTE Carbonic anhydrase 1.75e-21 0.44
CAH1_HUMAN CA1 Carbonic anhydrase 1 4.68e-21 0.51
Q3I4V7_CRYNV CAN2 Carbonic anhydrase 8.79e-20 0.46
CAH9_HUMAN CA9 Carbonic anhydrase 9 8.867e-20 0.51
LOX12_HUMAN ALOX12 Arachidonate 12-lipoxygenase, 12S-type 5.615e-19 0.34
Q5VLE3_EMEND rmtA RmtA 6.741e-19 0.30
Q9HVB9_PSEAE Carbonic anhydrase 9.803e-19 0.30
GLRA3_HUMAN GLRA3 Glycine receptor subunit alpha-3 1.125e-18 0.33
Q548M1_ECOLX groL 60 kDa chaperonin 5.446e-18 0.42
Q7BGE6_ECOLX groES 10 kDa chaperonin 5.446e-18 0.42
CAH1_HORSE CA1 Carbonic anhydrase 1 1.545e-17 0.33
CAH13_MOUSE Ca13 Carbonic anhydrase 13 2.253e-17 0.51
CAH15_MOUSE Ca15 Carbonic anhydrase 15 3.347e-17 0.44
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 3.478e-17 0.46
Q6FTL6_CANGA NCE103 Carbonic anhydrase 3.5e-17 0.46
SCN3A_RAT Scn3a Sodium channel protein type 3 subunit alpha 1.11e-16 0.31
FFAR4_RAT Ffar4 Free fatty acid receptor 4 1.443e-15 0.30
CP51_MYCTU cyp51 Lanosterol 14-alpha demethylase 1.887e-15 0.50
CAH6_HUMAN CA6 Carbonic anhydrase 6 1.921e-14 0.46
IKBA_HUMAN NFKBIA NF-kappa-B inhibitor alpha 3.619e-14 0.38
NMT_ASPFU nmt1 Glycylpeptide N-tetradecanoyltransferase 6.029e-14 0.32
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.117e-13 0.44
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.243e-13 0.47
LIMK2_HUMAN LIMK2 LIM domain kinase 2 1.281e-13 0.40
PFKA_TRYCC pfk ATP-dependent 6-phosphofructokinase 1.853e-13 0.30
BAZ2B_HUMAN BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 3.153e-13 0.36
PFKA_TRYBB pfk ATP-dependent 6-phosphofructokinase 1.437e-12 0.30
CAN_CANAL NCE103 Carbonic anhydrase 2.184e-12 0.46
ABCBB_RAT Abcb11 Bile salt export pump 5.427e-12 0.29
FFAR4_HUMAN FFAR4 Free fatty acid receptor 4 1.256e-11 0.33
EDNRA_RAT Ednra Endothelin-1 receptor 1.706e-11 0.46
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 2.386e-11 0.35
KMO_RAT Kmo Kynurenine 3-monooxygenase 2.414e-11 0.38
CAH5B_HUMAN CA5B Carbonic anhydrase 5B, mitochondrial 3.658e-11 0.46
SCN9A_HUMAN SCN9A Sodium channel protein type 9 subunit alpha 6.353e-11 0.37
5HT6R_HUMAN HTR6 5-hydroxytryptamine receptor 6 2.333e-10 0.53
PADI1_HUMAN PADI1 Protein-arginine deiminase type-1 7.541e-10 0.29
PADI2_HUMAN PADI2 Protein-arginine deiminase type-2 7.541e-10 0.29
PADI3_HUMAN PADI3 Protein-arginine deiminase type-3 7.541e-10 0.29
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 3.598e-09 0.29
SYLC_HUMAN LARS1 Leucine--tRNA ligase, cytoplasmic 4.08e-09 0.30
S22AC_HUMAN SLC22A12 Solute carrier family 22 member 12 4.633e-09 0.40
CAH14_HUMAN CA14 Carbonic anhydrase 14 5.982e-09 0.46
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 6.183e-09 0.31
EDNRA_HUMAN EDNRA Endothelin-1 receptor 1.825e-08 0.35
SCN9A_RAT Scn9a Sodium channel protein type 9 subunit alpha 2.372e-08 0.31
PHLP2_HUMAN PHLPP2 PH domain leucine-rich repeat-containing protein phosphatase 2 2.487e-08 0.31
5NTD_HUMAN NT5E 5'-nucleotidase 2.593e-08 0.41
TF65_HUMAN RELA Transcription factor p65 3.995e-08 0.38
CAH5A_HUMAN CA5A Carbonic anhydrase 5A, mitochondrial 4.418e-08 0.46
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 8.805e-08 0.36
NR1I2_HUMAN NR1I2 Nuclear receptor subfamily 1 group I member 2 1.221e-07 0.31
P3C2G_HUMAN PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma 1.422e-07 0.35
CAH7_HUMAN CA7 Carbonic anhydrase 7 5.684e-07 0.44
SCN8A_HUMAN SCN8A Sodium channel protein type 8 subunit alpha 5.762e-07 0.31
EAA2_HUMAN SLC1A2 Excitatory amino acid transporter 2 6.695e-07 0.39
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 8.944e-07 0.36
PADI4_HUMAN PADI4 Protein-arginine deiminase type-4 9.396e-07 0.29
MP2K6_HUMAN MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 1.574e-06 0.33
Q9BHT9_PLABE G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 1.877e-06 0.38
MCLN3_HUMAN MCOLN3 Mucolipin-3 3.486e-06 0.35
EAA1_HUMAN SLC1A3 Excitatory amino acid transporter 1 3.885e-06 0.39
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 4.37e-06 0.33
BRD4_HUMAN BRD4 Bromodomain-containing protein 4 4.389e-06 0.38
GRM4_HUMAN GRM4 Metabotropic glutamate receptor 4 4.664e-06 0.40
OXYR_HUMAN OXTR Oxytocin receptor 5.69e-06 0.38
PLEC_HUMAN PLEC Plectin 6.057e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 7.112e-06 0.29
GSK3B_RAT Gsk3b Glycogen synthase kinase-3 beta 7.294e-06 0.30
ANM1_HUMAN PRMT1 Protein arginine N-methyltransferase 1 8.247e-06 0.31
EDNRA_PIG EDNRA Endothelin-1 receptor 8.41e-06 0.32
GLRB_HUMAN GLRB Glycine receptor subunit beta 8.472e-06 0.32
CAH13_HUMAN CA13 Carbonic anhydrase 13 9.459e-06 0.42

Sapropterin

NOS1_HUMAN NOS1 Nitric oxide synthase, brain 0.001383 1.00
PH4H_HUMAN PAH Phenylalanine-4-hydroxylase 3.434e-100 0.80
PH4H_RAT Pah Phenylalanine-4-hydroxylase 3.238e-44 0.36
PUR2_MOUSE Gart Trifunctional purine biosynthetic protein adenosine-3 2.209e-40 0.38
MTDC_HUMAN MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 1.332e-36 0.29
NOS3_PIG NOS3 Nitric oxide synthase, endothelial 1.994e-31 0.61
PNPH_BOVIN PNP Purine nucleoside phosphorylase 1.17e-23 0.31
PUR2_HUMAN GART Trifunctional purine biosynthetic protein adenosine-3 3.878e-23 0.38
Q81VW8_BACAN folP Dihydropteroate synthase 7.948e-22 0.30
FOLC_MOUSE Fpgs Folylpolyglutamate synthase, mitochondrial 5.047e-19 0.29
SO1A3_RAT Slco1a3 Solute carrier organic anion transporter family member 1A3 8.07e-19 0.30
PNPH_MOUSE Pnp Purine nucleoside phosphorylase 9.056e-18 0.28
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 1.11e-16 0.29
DHPS_ECOLI folP Dihydropteroate synthase 6.217e-15 0.30
X5EH84_STAAU folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 9.182e-14 0.31
FOLC_HUMAN FPGS Folylpolyglutamate synthase, mitochondrial 2.181e-12 0.38
PNPH_RAT Pnp Purine nucleoside phosphorylase 6.572e-12 0.30
THIO_HUMAN TXN Thioredoxin 1.896e-08 0.30
FOLR1_HUMAN FOLR1 Folate receptor alpha 3.875e-08 0.29
PNPH_HUMAN PNP Purine nucleoside phosphorylase 5.696e-07 0.30

Chlorzoxazone

NOS3_HUMAN NOS3 Nitric oxide synthase, endothelial 0.001649 1.00
NOS1_RAT Nos1 Nitric oxide synthase, brain 0.01134 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.4034 1.00
KMO_PSEFL kmo Kynurenine 3-monooxygenase 6.387e-48 0.60
AHR_HUMAN AHR Aryl hydrocarbon receptor 7.302e-23 0.37
NMDE2_MOUSE Grin2b Glutamate receptor ionotropic, NMDA 2B 2.12e-22 0.36
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 2.723e-19 0.39
OXDA_PIG DAO D-amino-acid oxidase 2.205e-17 0.41
V1AR_MOUSE Avpr1a Vasopressin V1a receptor 2.674e-11 0.28
KMO_HUMAN KMO Kynurenine 3-monooxygenase 1.672e-10 0.60
MPIP3_HUMAN CDC25C M-phase inducer phosphatase 3 2.709e-10 0.33
LOX15_HUMAN ALOX15 Arachidonate 15-lipoxygenase 3.068e-10 0.34
ENPP2_RAT Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 6.311e-10 0.31
OXDA_RAT Dao D-amino-acid oxidase 1.173e-08 0.39
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 4.741e-08 0.33
OXDA_HUMAN DAO D-amino-acid oxidase 2.023e-07 0.41
ENPP2_MOUSE Enpp2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5.095e-07 0.31
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 9.755e-07 0.36
OGT1_HUMAN OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1.454e-06 0.31
CAH3_HUMAN CA3 Carbonic anhydrase 3 6.063e-06 0.36

Dexbrompheniramine

SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 0.002094 1.00
Q9WTR4_RAT Slc6a2 Transporter 0.002594 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.5904 1.00
HRH1_CAVPO HRH1 Histamine H1 receptor 2.521e-30 0.75
UR2R_HUMAN UTS2R Urotensin-2 receptor 1.324e-26 0.33
HRH1_RAT Hrh1 Histamine H1 receptor 1.577e-26 0.50
ATP6_MYCTU atpB ATP synthase subunit a 8.559e-25 0.30
ATPA_MYCTU atpA ATP synthase subunit alpha 8.559e-25 0.30
ATPB_MYCTU atpD ATP synthase subunit beta 8.559e-25 0.30
ATPE_MYCTU atpC ATP synthase epsilon chain 8.559e-25 0.30
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 8.559e-25 0.30
ATPF_MYCTU atpF ATP synthase subunit b 8.559e-25 0.30
ATPG_MYCTU atpG ATP synthase gamma chain 8.559e-25 0.30
ATPL_MYCTU atpE ATP synthase subunit c 8.559e-25 0.30
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.086e-17 0.75
HRH3_CAVPO HRH3 Histamine H3 receptor 8.882e-16 0.50
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 3.22e-15 0.75
CALM_BOVIN CALM Calmodulin 1.415e-10 0.28
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.079e-10 0.35
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 4.509e-10 0.75
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 9.827e-10 0.39
HRH1_HUMAN HRH1 Histamine H1 receptor 1.115e-09 0.75
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 1.537e-09 0.75
PPO1_AGABI PPO1 Polyphenol oxidase 1 2.039e-09 0.29
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.644e-09 0.75
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.614e-08 0.31

Mexiletine

SCN5A_HUMAN SCN5A Sodium channel protein type 5 subunit alpha 0.006589 1.00
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 0.7175 1.00
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 1.009e-74 0.72
TAAR1_MACMU TAAR1 Trace amine-associated receptor 1 2.387e-51 0.39
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 2.415e-28 0.41
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.861e-13 0.29
AOFA_RAT Maoa Amine oxidase [flavin-containing] A 1.846e-10 0.37
ADRB2_BOVIN ADRB2 Beta-2 adrenergic receptor 1.027e-09 0.33
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 2.488e-09 0.46
5HT1B_RAT Htr1b 5-hydroxytryptamine receptor 1B 6.611e-08 0.31
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 4.31e-07 0.44
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 1.469e-06 0.33

Methadone

OPRD_HUMAN OPRD1 Delta-type opioid receptor 0.02799 1.00
OPRM_HUMAN OPRM1 Mu-type opioid receptor 0.03864 1.00
MDR1_HUMAN ABCB1 ATP-dependent translocase ABCB1 0.1224 1.00
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 0.8831 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.9623 1.00
AMYP_RAT Amy2 Pancreatic alpha-amylase 2.155e-66 0.33
KIF11_HUMAN KIF11 Kinesin-like protein KIF11 1.704e-37 0.41
ACER2_HUMAN ACER2 Alkaline ceramidase 2 3.56e-37 0.29
UBC12_HUMAN UBE2M NEDD8-conjugating enzyme Ubc12 7.101e-36 0.28
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.068e-33 0.42
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 4.528e-20 0.42
E1BI31_BOVIN DPP9 Dipeptidyl peptidase 9 4.879e-18 0.29
USP_DROME usp Protein ultraspiracle 6.661e-16 0.32
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 2.22e-15 0.29
K4JQ36_LAOST ace2 Carboxylic ester hydrolase 4.441e-15 0.29
Q8WMX0_BOVIN Muscarinic receptor M1 1.932e-13 0.33
NEP_MOUSE Mme Neprilysin 2.173e-13 0.29
ECR_DROME EcR Ecdysone receptor 4.571e-13 0.32
ECR_BOMMO EcR Ecdysone receptor 1.082e-11 0.33
CALM_BOVIN CALM Calmodulin 3.542e-11 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 7.003e-11 0.38
KCNN4_HUMAN KCNN4 Intermediate conductance calcium-activated potassium channel protein 4 7.554e-11 0.33
Q7YWJ9_MUSDO Ache Carboxylic ester hydrolase 1.105e-10 0.29
Q9NJH6_NEPCI AO-AChE Ace-orthologous acetylcholinesterase 1.105e-10 0.29
EST1_RABIT Liver carboxylesterase 1 1.464e-09 0.30
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 2.118e-09 0.39
ACHB4_RAT Chrnb4 Neuronal acetylcholine receptor subunit beta-4 3.396e-09 0.41
Q79MP6_PSEAI blaIMP-1 Beta-lactamase 7.896e-09 0.31
E3UJZ5_SPOLI Ecdysone receptor 3.092e-08 0.32
GBRB1_HUMAN GABRB1 Gamma-aminobutyric acid receptor subunit beta-1 3.301e-08 0.29
EST2_HUMAN CES2 Cocaine esterase 4.053e-08 0.33
EST1_HUMAN CES1 Liver carboxylesterase 1 5.346e-08 0.33
COLA_CLOPE colA Collagenase ColA 6.412e-08 0.30
ACHA3_RAT Chrna3 Neuronal acetylcholine receptor subunit alpha-3 5.636e-07 0.33
CA2D1_MOUSE Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 7.106e-07 0.33
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 7.895e-07 0.29
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 1.782e-06 0.35
CEL2A_PIG CELA2A Chymotrypsin-like elastase family member 2A 2.034e-06 0.30
CBPA1_BOVIN CPA1 Carboxypeptidase A1 3.85e-06 0.33
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 4.818e-06 0.30
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.799e-06 0.28
RIPK1_HUMAN RIPK1 Receptor-interacting serine/threonine-protein kinase 1 7.369e-06 0.33
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 7.451e-06 0.30
AGP1_YEAST AGP1 General amino acid permease AGP1 8.09e-06 0.28

Mefloquine

AA2AR_HUMAN ADORA2A Adenosine receptor A2a 0.064 1.00
AA1R_HUMAN ADORA1 Adenosine receptor A1 0.2103 1.00
AA2BR_HUMAN ADORA2B Adenosine receptor A2b 0.6893 1.00
KCNH2_HUMAN KCNH2 Potassium voltage-gated channel subfamily H member 2 0.7724 1.00
AA3R_HUMAN ADORA3 Adenosine receptor A3 0.9869 1.00
IDHP_HUMAN IDH2 Isocitrate dehydrogenase [NADP], mitochondrial 1.321e-14 0.29
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 7.228e-14 0.37
B0FL73_CAVPO ADRB1 Beta-1 adrenergic receptor 2.292e-12 0.39
ADRB2_CAVPO Adrb2 Beta-2 adrenergic receptor 7.431e-11 0.39
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 6.528e-07 0.34
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 7.334e-07 0.34

Vinorelbine

NK2R_HUMAN TACR2 Substance-K receptor 0.1254 1.00
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 0.886 1.00
Q25270_LEIDO beta-tubulin Beta-tubulin 2.843e-28 0.75
NR0B1_HUMAN NR0B1 Nuclear receptor subfamily 0 group B member 1 5.258e-18 0.67
TRPM8_MOUSE Trpm8 Transient receptor potential cation channel subfamily M member 8 1.199e-14 0.35
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.822e-07 0.75

Dydrogesterone

CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 0.2784 1.00
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.143e-184 0.45
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 8.022e-123 0.45
3BHS1_HUMAN HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1.56e-90 0.44
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.063e-71 0.56
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 8.841e-58 0.32
SHBG_HUMAN SHBG Sex hormone-binding globulin 5.835e-57 0.59
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 6.441e-51 0.46
ANDR_RAT Ar Androgen receptor 8.433e-45 0.59
Q690N0_BOVIN PGR Progesterone receptor 1.215e-43 0.59
CP19A_HUMAN CYP19A1 Aromatase 1.035e-42 0.63
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 1.228e-33 0.59
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.468e-32 0.41
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 5.916e-32 0.36
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.762e-26 0.37
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 1.304e-25 0.38
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 8.689e-25 0.48
ADCYA_HUMAN ADCY10 Adenylate cyclase type 10 2.608e-23 0.37
SHBG_RAT Shbg Sex hormone-binding globulin 4.185e-23 0.28
GBRG1_RAT Gabrg1 Gamma-aminobutyric acid receptor subunit gamma-1 2.35e-21 0.33
NR1I3_MOUSE Nr1i3 Nuclear receptor subfamily 1 group I member 3 6e-20 0.32
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 1.072e-19 0.46
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 1.935e-19 0.59
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 3.553e-18 0.59
GBRB2_HUMAN GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 9.581e-18 0.38
ANDR_MOUSE Ar Androgen receptor 3.331e-16 0.59
S22A1_HUMAN SLC22A1 Solute carrier family 22 member 1 1.373e-13 0.59
ERG2_YEAST ERG2 C-8 sterol isomerase 9.636e-13 0.59
GCR_MOUSE Nr3c1 Glucocorticoid receptor 1.417e-10 0.31
GBRD_HUMAN GABRD Gamma-aminobutyric acid receptor subunit delta 5.463e-10 0.38
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 6.358e-10 0.39
MCR_HUMAN NR3C2 Mineralocorticoid receptor 1.01e-09 0.59
PRGR_RABIT PGR Progesterone receptor 1.951e-09 0.59
CP19A_RAT Cyp19a1 Aromatase 1.55e-07 0.36
GBRA1_HUMAN GABRA1 Gamma-aminobutyric acid receptor subunit alpha-1 2.376e-07 0.38
ANDR_HUMAN AR Androgen receptor 1.896e-06 0.59
GBRG2_HUMAN GABRG2 Gamma-aminobutyric acid receptor subunit gamma-2 2.501e-06 0.38
MCR_RAT Nr3c2 Mineralocorticoid receptor 6.113e-06 0.36

Phenoxymethylpenicillin

CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 0.3161 1.00
O60989_PLAVI Aspartic protease PM4 7.341e-68 0.29
BLAB_BACCE Metallo-beta-lactamase type 2 1.955e-53 0.46
PBPX_STRPN pbpX Penicillin-binding protein 2x 5.927e-51 0.41
PAQR1_HUMAN ADIPOR1 Adiponectin receptor protein 1 4.407e-45 0.36
PAQR2_HUMAN ADIPOR2 Adiponectin receptor protein 2 4.407e-45 0.36
TRAR_RHIRD traR Transcriptional activator protein TraR 2.604e-41 0.35
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 5.87e-39 0.49
D5HSX5_9GAMM blaPER-6 Beta-lactamase 4.749e-37 0.29
Q0VTR6_ACIPI adc-14 Beta-lactamase 4.749e-37 0.29
Q0VTR8_ACIPI adc-16 Beta-lactamase 4.749e-37 0.29
Q7X575_ECOLX SHV-11 Beta-lactamase 4.749e-37 0.29
BLA5_KLEPN bla Beta-lactamase SHV-5 9.406e-37 0.29
Q9Y006_PLAFA hap HAP protein 1.572e-36 0.29
Q3S5C3_SALNE sugE Efflux transporter 4.51e-30 0.49
Q48435_KLEPN bla LAT-2 Beta-lactamase 4.51e-30 0.49
BLAC_STAAU blaZ Beta-lactamase 1.467e-25 0.35
Q6A2E2_AEDAE ace-1 Acetylcholinesterase 6.243e-24 0.29
A1E3K9_ECOLX blaSCO-1 Beta-lactamase 7.498e-24 0.29
A8RR46_BACCS bcl1 Beta-lactamase 7.498e-24 0.29
D2SSQ3_PSEAI Beta-lactamase 7.498e-24 0.29
Q3SAW3_PSEAI bla(BEL1) Beta-lactamase 7.498e-24 0.29
BLA1_KLEPN bla Beta-lactamase SHV-1 1.158e-23 0.29
PPME1_HUMAN PPME1 Protein phosphatase methylesterase 1 1.926e-23 0.29
A2RP81_CITFR blaPER-2 Beta-lactamase 2.29e-22 0.50
PLM2_PLAFA Plasmepsin-2 5.049e-22 0.33
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 2.502e-19 0.37
D1MIX9_PSEAI blaGES-13 Beta-lactamase 1.753e-18 0.29
AMPC_ECOLI ampC Beta-lactamase 1.365e-17 0.50
PTPRE_HUMAN PTPRE Receptor-type tyrosine-protein phosphatase epsilon 5.551e-16 0.30
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 2.22e-15 0.29
BLAT_ECOLX bla; blaT-3; blaT-4; blaT-5; blaT-6 Beta-lactamase TEM 1.854e-14 0.30
LUXS_ALIF1 luxR Transcriptional activator protein LuxR 4.219e-14 0.35
Q5NGQ3_FRATT fabI Enoyl-[acyl-carrier-protein] reductase [NADH] 2.268e-13 0.33
AMPC_CITFR ampC Beta-lactamase 5.743e-12 0.29
BLAC_BACLI penP Beta-lactamase 5.743e-12 0.29
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 5.743e-12 0.29
MK03_HUMAN MAPK3 Mitogen-activated protein kinase 3 6.639e-12 0.29
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 2.44e-11 0.33
FGF1_HUMAN FGF1 Fibroblast growth factor 1 6.557e-10 0.33
BLA1_STEMA Metallo-beta-lactamase L1 type 3 9.72e-10 0.31
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 1.496e-09 0.30
LOX15_RAT Alox15 Arachidonate 15-lipoxygenase 1.461e-08 0.29
FGF2_HUMAN FGF2 Fibroblast growth factor 2 4.403e-08 0.33
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 1.291e-07 0.33
CASP8_HUMAN CASP8 Caspase-8 1.947e-07 0.33
CASP1_HUMAN CASP1 Caspase-1 2.057e-07 0.33
Q9RMS5_PSEAI phzR LuxR family transcriptional regulator 2.105e-07 0.29
STA5A_HUMAN STAT5A Signal transducer and activator of transcription 5A 1.032e-06 0.28
STRP_STRP1 ska Streptokinase A 1.595e-06 0.84
FABPH_HUMAN FABP3 Fatty acid-binding protein, heart 2.03e-06 0.29
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 4.151e-06 0.30
AMPC_ENTCL ampC Beta-lactamase 4.489e-06 0.33
VEGFA_HUMAN VEGFA Vascular endothelial growth factor A 5.201e-06 0.33
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 7.705e-06 0.28
CASP7_HUMAN CASP7 Caspase-7 8.862e-06 0.33

Metformin

STRP_STRP1 ska Streptokinase A 0.905 1.00

Pimecrolimus

PP2BA_HUMAN PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 1.633e-231 0.80
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 1.358e-166 0.91
FKB1A_MOUSE Fkbp1a Peptidyl-prolyl cis-trans isomerase FKBP1A 1.31e-106 0.39
FKB1B_HUMAN FKBP1B Peptidyl-prolyl cis-trans isomerase FKBP1B 1.321e-58 0.80
SO1B1_HUMAN SLCO1B1 Solute carrier organic anion transporter family member 1B1 3.534e-23 0.80
SF3B3_HUMAN SF3B3 Splicing factor 3B subunit 3 2.621e-21 0.80
FKBP4_HUMAN FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4 4.441e-16 0.91
PDCD4_HUMAN PDCD4 Programmed cell death protein 4 1.152e-10 0.36
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 2.551e-09 0.80

Ceruletide

CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 1.586e-205 0.60
MC5R_MOUSE Mc5r Melanocortin receptor 5 1.963e-199 0.45
MC4R_MOUSE Mc4r Melanocortin receptor 4 4.436e-164 0.45
MC3R_MOUSE Mc3r Melanocortin receptor 3 1.286e-159 0.45
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 4.886e-151 0.60
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 7.139e-151 0.44
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 1.458e-146 0.60
CD36_RAT Cd36 Platelet glycoprotein 4 1.684e-135 0.41
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 1.434e-134 0.45
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 2.245e-126 0.45
NK2R_MESAU TACR2 Substance-K receptor 8.247e-122 0.51
MC3R_HUMAN MC3R Melanocortin receptor 3 3.857e-107 0.44
EDNRB_RAT Ednrb Endothelin receptor type B 4.877e-107 0.44
MMP11_MOUSE Mmp11 Stromelysin-3 6.557e-106 0.36
NK1R_CAVPO TACR1 Substance-P receptor 5.975e-102 0.62
OPRM_RAT Oprm1 Mu-type opioid receptor 1.962e-93 0.48
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 2.299e-92 0.44
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 2.157e-91 0.49
KISSR_HUMAN KISS1R KiSS-1 receptor 5.822e-89 0.47
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 1.055e-85 0.43
MC4R_HUMAN MC4R Melanocortin receptor 4 1.194e-84 0.45
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 5.413e-81 0.35
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 6.561e-80 0.36
EDNRA_MOUSE Ednra Endothelin-1 receptor 2.292e-79 0.43
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 5.752e-77 0.35
O57585_DANRE oprd1a Opioid receptor homologue 5.752e-77 0.35
NK2R_RAT Tacr2 Substance-K receptor 9.419e-77 0.50
OPRD_RAT Oprd1 Delta-type opioid receptor 7.582e-73 0.45
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.128e-72 0.56
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 1.169e-69 0.35
GRPR_RAT Grpr Gastrin-releasing peptide receptor 2.327e-69 0.48
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 3.298e-68 0.30
OPRM_CAVPO OPRM1 Mu-type opioid receptor 3.343e-68 0.48
MMP11_HUMAN MMP11 Stromelysin-3 1.285e-67 0.34
RENI_RAT Ren1 Renin 8.059e-67 0.36
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 4.182e-64 0.44
CCKAR_RAT Cckar Cholecystokinin receptor type A 4.767e-64 0.60
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 7.093e-64 0.34
OPRD_MOUSE Oprd1 Delta-type opioid receptor 1.773e-63 0.48
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.714e-60 0.42
OST48_HUMAN DDOST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit 2.1e-60 0.33
PRO_HTL1A gag-pro Gag-Pro polyprotein 3.201e-58 0.38
NK3R_CAVPO TACR3 Neuromedin-K receptor 7.519e-58 0.56
EDNRA_PIG EDNRA Endothelin-1 receptor 1.065e-57 0.44
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 2.026e-56 0.37
FURIN_HUMAN FURIN Furin 4.479e-56 0.38
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 1.059e-54 0.34
SURA_ECOLI surA Chaperone SurA 9.185e-54 0.43
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 3.86e-53 0.35
F1SH20_PIG TRHDE Uncharacterized protein 1.096e-51 0.30
NK2R_RABIT TACR2 Substance-K receptor 2.089e-50 0.50
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 1.057e-49 0.36
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 1.731e-49 0.41
RIR1_MOUSE Rrm1 Ribonucleoside-diphosphate reductase large subunit 3.842e-49 0.31
ANPRC_HUMAN NPR3 Atrial natriuretic peptide receptor 3 5.429e-49 0.31
NK3R_RAT Tacr3 Neuromedin-K receptor 3.769e-48 0.42
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 1.178e-47 0.33
O68720_YERPE yopH Targeted effector protein 2.606e-47 0.35
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 8.059e-47 0.43
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 1.459e-46 0.34
OPRX_MOUSE Oprl1 Nociceptin receptor 1.668e-46 0.36
SHC1_HUMAN SHC1 SHC-transforming protein 1 1.596e-45 0.31
NK1R_RAT Tacr1 Substance-P receptor 8.255e-44 0.45
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 2.801e-42 0.35
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 5.308e-41 0.33
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 5.308e-41 0.33
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 7.042e-41 0.32
EDNRA_HUMAN EDNRA Endothelin-1 receptor 1.434e-40 0.44
BXA1_CLOBH botA Botulinum neurotoxin type A 2.038e-40 0.35
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 3.451e-39 0.43
NMBR_RAT Nmbr Neuromedin-B receptor 4.024e-39 0.49
NMBR_HUMAN NMBR Neuromedin-B receptor 1.665e-38 0.50
NEP_RABIT MME Neprilysin 1.67e-38 0.36
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 2.943e-38 0.32
PSB6_YEAST PRE7 Proteasome subunit beta type-6 3.271e-38 0.30
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.102e-37 0.31
ECE1_RAT Ece1 Endothelin-converting enzyme 1 2.315e-37 0.35
IL1RA_MOUSE Il1rn Interleukin-1 receptor antagonist protein 3.127e-37 0.29
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 9.744e-37 0.56
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 1.754e-36 0.43
Q6IE76_BOVIN FDFT1 FDFT1 protein 3.875e-36 0.29
MMP8_HUMAN MMP8 Neutrophil collagenase 2.556e-35 0.36
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 8.28e-35 0.30
MRAY_STAAU mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase 8.747e-35 0.30
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 2.828e-34 0.46
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 3.246e-34 0.41
MRGX1_MOUSE Mrgprx1 Mas-related G-protein coupled receptor member X1 1.21e-33 0.29
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 3.334e-33 0.34
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 1.254e-32 0.44
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 5.744e-32 0.53
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.782e-31 0.34
ELAS_PSEAE lasB Elastase 2.15e-30 0.42
O07911_STAAU agrC AgrC 3.156e-30 0.29
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 5.97e-30 0.36
RENI_HUMAN REN Renin 1.052e-29 0.39
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 1.94e-29 0.36
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 3.357e-29 0.36
ACE_RAT Ace Angiotensin-converting enzyme 7.338e-29 0.36
CATE_HUMAN CTSE Cathepsin E 8.216e-29 0.33
NK3R_HUMAN TACR3 Neuromedin-K receptor 8.805e-29 0.52
MMP8_RAT Mmp8 Neutrophil collagenase 1.035e-28 0.34
OPRD_HUMAN OPRD1 Delta-type opioid receptor 1.66e-28 0.51
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 1.655e-27 0.40
FSHR_RAT Fshr Follicle-stimulating hormone receptor 8.014e-27 0.33
MMP2_HUMAN MMP2 72 kDa type IV collagenase 7.758e-26 0.36
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.369e-24 0.30
OPRK_RAT Oprk1 Kappa-type opioid receptor 1.65e-24 0.41
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 2.518e-24 0.35
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 1.384e-23 0.36
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 1.599e-23 0.29
DLG4_HUMAN DLG4 Disks large homolog 4 1.887e-23 0.31
HDA11_HUMAN HDAC11 Histone deacetylase 11 1.924e-23 0.35
CASPA_HUMAN CASP10 Caspase-10 2.154e-23 0.42
A4HSF7_LEIIN TRYR Trypanothione reductase 2.847e-23 0.29
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 4.177e-22 0.33
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 2.629e-21 0.42
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 5.65e-21 0.30
TYRO_HUMAN TYR Tyrosinase 6.318e-21 0.37
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.106e-19 0.34
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 1.348e-19 0.35
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.488e-19 0.41
HDA10_HUMAN HDAC10 Polyamine deacetylase HDAC10 3.513e-19 0.35
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 3.678e-19 0.35
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 3.959e-19 0.37
PSB5_YEAST PRE2 Proteasome subunit beta type-5 4.754e-19 0.30
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 4.98e-19 0.36
CASP9_HUMAN CASP9 Caspase-9 6.771e-19 0.42
IDE_HUMAN IDE Insulin-degrading enzyme 6.879e-19 0.41
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 6.993e-19 0.36
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 9.504e-19 0.30
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 2.032e-18 0.29
OPRM_HUMAN OPRM1 Mu-type opioid receptor 2.529e-18 0.51
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 3.785e-18 0.33
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 3.959e-18 0.36
Q72874_9HIV1 pol Pol polyprotein 5.248e-18 0.37
ANPRA_HUMAN NPR1 Atrial natriuretic peptide receptor 1 1.339e-17 0.31
FA12_HUMAN F12 Coagulation factor XII 2.629e-17 0.30
CATL1_HUMAN CTSL Cathepsin L1 2.718e-17 0.39
MMP1_HUMAN MMP1 Interstitial collagenase 3.915e-17 0.37
MMP17_HUMAN MMP17 Matrix metalloproteinase-17 4.309e-17 0.30
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.171e-17 0.30
THER_BACTH npr Thermolysin 5.221e-17 0.34
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.11e-16 0.35
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 2.22e-16 0.50
ACE_HUMAN ACE Angiotensin-converting enzyme 3.331e-16 0.44
NRP1_RAT Nrp1 Neuropilin-1 3.331e-16 0.40
ENV_HV1H2 env Envelope glycoprotein gp160 5.551e-16 0.35
NPY4R_HUMAN NPY4R Neuropeptide Y receptor type 4 1.332e-15 0.31
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 1.554e-15 0.33
MMP12_HUMAN MMP12 Macrophage metalloelastase 2.442e-15 0.31
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.887e-15 0.35
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 4.108e-15 0.34
NK1R_HUMAN TACR1 Substance-P receptor 5.773e-15 0.40
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 7.105e-15 0.37
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 7.327e-15 0.34
HDAC2_HUMAN HDAC2 Histone deacetylase 2 8.993e-15 0.35
MC5R_HUMAN MC5R Melanocortin receptor 5 5.151e-14 0.43
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 5.429e-14 0.35
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 5.684e-14 0.34
ADA12_HUMAN ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 6.173e-14 0.30
NK2R_HUMAN TACR2 Substance-K receptor 6.55e-14 0.41
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 1.216e-13 0.30
CBX7_HUMAN CBX7 Chromobox protein homolog 7 3.543e-13 0.35
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 3.691e-13 0.38
EDNRB_HUMAN EDNRB Endothelin receptor type B 4.017e-13 0.38
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 4.026e-13 0.33
AMPN_HUMAN ANPEP Aminopeptidase N 4.748e-13 0.31
HDAC3_HUMAN HDAC3 Histone deacetylase 3 7.611e-13 0.35
MMP9_RAT Mmp9 Matrix metalloproteinase-9 1.27e-12 0.34
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 4.237e-12 0.32
PEPA_PIG PGA Pepsin A 4.948e-12 0.34
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 6.162e-12 0.34
CASP4_HUMAN CASP4 Caspase-4 9.907e-12 0.42
MMP10_HUMAN MMP10 Stromelysin-2 1.577e-11 0.31
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 3.336e-11 0.30
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 3.659e-11 0.32
GHSR_RAT Ghsr Growth hormone secretagogue receptor type 1 3.788e-11 0.38
TF2AA_HUMAN GTF2A1 Transcription initiation factor IIA subunit 1 3.911e-11 0.29
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 8.589e-11 0.41
FCER2_HUMAN FCER2 Low affinity immunoglobulin epsilon Fc receptor 9.159e-11 0.31
MMP7_HUMAN MMP7 Matrilysin 9.71e-11 0.40
Q4U254_9ENTO protease Protease 1.229e-10 0.33
CATD_HUMAN CTSD Cathepsin D 1.546e-10 0.36
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 2.742e-10 0.35
TAT_HV1H2 tat Protein Tat 2.816e-10 0.30
EDNRB_PIG EDNRB Endothelin receptor type B 6.07e-10 0.33
NEP_PIG MME Neprilysin 1.087e-09 0.28
TIMP3_RAT Timp3 Metalloproteinase inhibitor 3 1.631e-09 0.34
NMDE1_RAT Grin2a Glutamate receptor ionotropic, NMDA 2A 2.21e-09 0.33
SIR1_HUMAN SIRT1 NAD-dependent protein deacetylase sirtuin-1 2.254e-09 0.33
CASP1_HUMAN CASP1 Caspase-1 2.3e-09 0.42
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 3.247e-09 0.41
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 4.338e-09 0.32
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 4.95e-09 0.28
POLG_DEN26 Genome polyprotein 5.186e-09 0.28
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 5.786e-09 0.30
PAPA1_CARPA Papain 6.191e-09 0.37
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 8.982e-09 0.30
PAR1_HUMAN F2R Proteinase-activated receptor 1 9.556e-09 0.32
NEP_HUMAN MME Neprilysin 1.207e-08 0.36
HEPS_HUMAN HPN Serine protease hepsin 1.293e-08 0.35
GRIA1_RAT Gria1 Glutamate receptor 1 1.335e-08 0.33
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 2.017e-08 0.30
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 2.017e-08 0.30
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 2.16e-08 0.33
CASP5_HUMAN CASP5 Caspase-5 2.301e-08 0.42
CATB_HUMAN CTSB Cathepsin B 2.324e-08 0.38
Q9YQ12_9HIV1 protease Protease 4.301e-08 0.37
FA7_HUMAN F7 Coagulation factor VII 4.707e-08 0.34
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 4.867e-08 0.28
MMP3_HUMAN MMP3 Stromelysin-1 5.111e-08 0.34
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 5.236e-08 0.35
FNTA_BOVIN FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 6.119e-08 0.32
HDAC8_HUMAN HDAC8 Histone deacetylase 8 7.677e-08 0.35
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 8.219e-08 0.34
Q82323_9DELA Protease 8.514e-08 0.38
MMP26_HUMAN MMP26 Matrix metalloproteinase-26 8.775e-08 0.30
5HT1D_CAVPO HTR1D 5-hydroxytryptamine receptor 1D 1.075e-07 0.33
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 1.099e-07 0.30
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 1.099e-07 0.30
BACE1_HUMAN BACE1 Beta-secretase 1 1.241e-07 0.35
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.473e-07 0.30
KLKB1_HUMAN KLKB1 Plasma kallikrein 1.522e-07 0.36
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.545e-07 0.32
A3EZI9_9HEPC NS3 Genome polyprotein 1.662e-07 0.36
PROC_HUMAN PROC Vitamin K-dependent protein C 1.715e-07 0.30
Q95PM0_TRYBR rhodesain Cysteine protease 1.775e-07 0.33
KLK1_HUMAN KLK1 Kallikrein-1 1.892e-07 0.32
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.951e-07 0.30
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.114e-07 0.33
CCNA2_HUMAN CCNA2 Cyclin-A2 2.205e-07 0.32
NEP_RAT Mme Neprilysin 2.533e-07 0.35
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.628e-07 0.33
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 5.949e-07 0.39
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 6.759e-07 0.30
A0A0C7ACN7_PSEAI pqsD 3-oxoacyl-ACP synthase 7.518e-07 0.29
HDAC1_HUMAN HDAC1 Histone deacetylase 1 7.642e-07 0.35
Q91H74_9FLAV Genome polyprotein 8.481e-07 0.37
CATD_BOVIN CTSD Cathepsin D 8.518e-07 0.32
PGTB1_BOVIN PGGT1B Geranylgeranyl transferase type-1 subunit beta 8.679e-07 0.31
FPR2_HUMAN FPR2 N-formyl peptide receptor 2 8.763e-07 0.44
BLA1_STEMA Metallo-beta-lactamase L1 type 3 1.09e-06 0.31
Q82134_9DELA prt Protease 1.215e-06 0.38
UR2R_RAT Uts2r Urotensin-2 receptor 1.38e-06 0.40
CASP8_HUMAN CASP8 Caspase-8 1.548e-06 0.42
ITA4_HUMAN ITGA4 Integrin alpha-4 1.62e-06 0.31
TAOK3_HUMAN TAOK3 Serine/threonine-protein kinase TAO3 2.418e-06 0.38
CASP7_HUMAN CASP7 Caspase-7 2.503e-06 0.38
PLMN_HUMAN PLG Plasminogen 2.772e-06 0.33
ITB1_HUMAN ITGB1 Integrin beta-1 2.869e-06 0.31
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 3.23e-06 0.30
MMP15_HUMAN MMP15 Matrix metalloproteinase-15 3.285e-06 0.30
IMDH1_HUMAN IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 3.348e-06 0.29
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 3.656e-06 0.31
R1AB_SARS rep Replicase polyprotein 1ab 5.749e-06 0.30
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 5.799e-06 0.32
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 6.086e-06 0.29
PTPRA_HUMAN PTPRA Receptor-type tyrosine-protein phosphatase alpha 7.232e-06 0.32
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 8.004e-06 0.32
PSA1_HUMAN PSMA1 Proteasome subunit alpha type-1 8.017e-06 0.32
PSA2_HUMAN PSMA2 Proteasome subunit alpha type-2 8.017e-06 0.32
PSA3_HUMAN PSMA3 Proteasome subunit alpha type-3 8.017e-06 0.32
PSA4_HUMAN PSMA4 Proteasome subunit alpha type-4 8.017e-06 0.32
PSA5_HUMAN PSMA5 Proteasome subunit alpha type-5 8.017e-06 0.32
PSA6_HUMAN PSMA6 Proteasome subunit alpha type-6 8.017e-06 0.32
PSA7_HUMAN PSMA7 Proteasome subunit alpha type-7 8.017e-06 0.32
PSB11_HUMAN PSMB11 Proteasome subunit beta type-11 8.017e-06 0.32
PSB3_HUMAN PSMB3 Proteasome subunit beta type-3 8.017e-06 0.32
PSB4_HUMAN PSMB4 Proteasome subunit beta type-4 8.017e-06 0.32
PSB6_HUMAN PSMB6 Proteasome subunit beta type-6 8.017e-06 0.32
PSB7_HUMAN PSMB7 Proteasome subunit beta type-7 8.017e-06 0.32
PSMA8_HUMAN PSMA8 Proteasome subunit alpha-type 8 8.017e-06 0.32

Acetohexamide

HYEP_MOUSE Ephx1 Epoxide hydrolase 1 1.241e-156 0.62
HYEP_HUMAN EPHX1 Epoxide hydrolase 1 1.334e-119 0.62
HYES_HUMAN EPHX2 Bifunctional epoxide hydrolase 2 5.855e-49 0.56
HYES_MOUSE Ephx2 Bifunctional epoxide hydrolase 2 4.502e-44 0.42
AOC3_MOUSE Aoc3 Membrane primary amine oxidase 4.241e-32 0.32
PPIA_RAT Ppia Peptidyl-prolyl cis-trans isomerase A 2.633e-25 0.30
FAAH2_HUMAN FAAH2 Fatty-acid amide hydrolase 2 8.615e-25 0.31
Q26964_TRYCR TCTS-154 Trans-sialidase 1.239e-23 0.29
F16P1_HUMAN FBP1 Fructose-1,6-bisphosphatase 1 9.657e-23 0.36
EPHB_MYCTO Epoxide hydrolase B 6.654e-21 0.33
ABCC8_HUMAN ABCC8 ATP-binding cassette sub-family C member 8 2.532e-19 0.47
ABCBB_RAT Abcb11 Bile salt export pump 9.676e-19 0.47
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 5.175e-18 0.40
STS_HUMAN STS Steryl-sulfatase 3.331e-16 0.34
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 1.887e-15 0.29
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 2.132e-14 0.38
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.28e-13 0.47
TS1R2_HUMAN TAS1R2 Taste receptor type 1 member 2 1.871e-13 0.35
ACHG_HUMAN CHRNG Acetylcholine receptor subunit gamma 7.078e-13 0.29
ACHB_HUMAN CHRNB1 Acetylcholine receptor subunit beta 1.743e-12 0.29
ACHD_HUMAN CHRND Acetylcholine receptor subunit delta 3.059e-12 0.29
TS1R3_HUMAN TAS1R3 Taste receptor type 1 member 3 3.357e-12 0.35
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 3.653e-12 0.47
HRH2_HUMAN HRH2 Histamine H2 receptor 2.934e-11 0.38
VIPR2_HUMAN VIPR2 Vasoactive intestinal polypeptide receptor 2 3.26e-11 0.32
CAH1_HUMAN CA1 Carbonic anhydrase 1 5.747e-11 0.47
ACHA_HUMAN CHRNA1 Acetylcholine receptor subunit alpha 9.804e-11 0.29
I23O1_HUMAN IDO1 Indoleamine 2,3-dioxygenase 1 1.404e-10 0.31
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.784e-10 0.33
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.627e-10 0.47
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 6.32e-10 0.29
CAH9_HUMAN CA9 Carbonic anhydrase 9 8.151e-10 0.48
CAH12_HUMAN CA12 Carbonic anhydrase 12 1.516e-09 0.48
NCEH1_HUMAN NCEH1 Neutral cholesterol ester hydrolase 1 1.743e-09 0.32
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.875e-09 0.41
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 3.055e-09 0.29
HAOX1_HUMAN HAO1 Hydroxyacid oxidase 1 4.934e-09 0.34
MEP1B_HUMAN MEP1B Meprin A subunit beta 1.422e-08 0.29
LIMK2_HUMAN LIMK2 LIM domain kinase 2 2.205e-08 0.33
ALR_HUMAN GFER FAD-linked sulfhydryl oxidase ALR 5.302e-08 0.49
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 8.142e-08 0.36
HCAR3_HUMAN HCAR3 Hydroxycarboxylic acid receptor 3 9.639e-08 0.33
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.504e-07 0.32
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1.664e-07 0.29
CAH14_HUMAN CA14 Carbonic anhydrase 14 1.969e-07 0.35
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 2.059e-07 0.35
HXK4_RAT Gck Hexokinase-4 3.865e-07 0.29
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 3.96e-07 0.30
CAH7_HUMAN CA7 Carbonic anhydrase 7 7.219e-07 0.35
QPCTL_HUMAN QPCTL Glutaminyl-peptide cyclotransferase-like protein 9.577e-07 0.30
PANC_MYCTU panC Pantothenate synthetase 1.069e-06 0.34
P96878_MYCTU Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase) 1.174e-06 0.47
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.469e-06 0.30
Q0GKD7_LEIDO Farnesyl pyrophosphate synthase 1.771e-06 0.29
Q25270_LEIDO beta-tubulin Beta-tubulin 2.185e-06 0.29
CDKA1_HUMAN CDK2AP1 Cyclin-dependent kinase 2-associated protein 1 2.849e-06 0.29
LSHR_HUMAN LHCGR Lutropin-choriogonadotropic hormone receptor 2.917e-06 0.30
A5H660_SCHMA HDAC8 Histone deacetylase 8 4.052e-06 0.34
S5A2_RAT Srd5a2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 4.142e-06 0.29
Q03732_HBV HBcAg Capsid protein 4.618e-06 0.32
MBTD1_HUMAN MBTD1 MBT domain-containing protein 1 5.7e-06 0.28
MTCA1_MYCTU mtcA1 Beta-carbonic anhydrase 1 5.924e-06 0.47
PAFA_HUMAN PLA2G7 Platelet-activating factor acetylhydrolase 9.536e-06 0.32

Beclomethasone_dipropionate

ATTY_RAT Tat Tyrosine aminotransferase 2.2e-142 0.54
GCR_RAT Nr3c1 Glucocorticoid receptor 4.454e-80 0.80
Q690N0_BOVIN PGR Progesterone receptor 4.095e-46 0.69
GCR_HUMAN NR3C1 Glucocorticoid receptor 1.924e-29 0.69
GCR_MOUSE Nr3c1 Glucocorticoid receptor 9.476e-18 0.43
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 2.376e-14 0.32
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.159e-10 0.32
GLNA_HUMAN GLUL Glutamine synthetase 4.159e-10 0.32
IL6_HUMAN IL6 Interleukin-6 4.329e-08 0.32
MMP1_HUMAN MMP1 Interstitial collagenase 1.499e-07 0.56

Aztreonam

PBPA_PSEAE mrcA Penicillin-binding protein 1A 2.415e-111 0.72
Q83TT7_ECOLX ampC AmpC 2.429e-82 0.72
B2ZTR6_ACIBA Beta-lactamase 4.432e-65 0.72
D6NSM8_ACIBA ampC Beta-lactamase 4.432e-65 0.72
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.421e-57 0.72
Q3S5C3_SALNE sugE Efflux transporter 2.355e-44 0.72
Q48435_KLEPN bla LAT-2 Beta-lactamase 2.355e-44 0.72
A2RP81_CITFR blaPER-2 Beta-lactamase 5.589e-32 0.72
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 8.203e-20 0.34
AMPC_CITFR ampC Beta-lactamase 6.861e-13 0.32
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 2.098e-12 0.34
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 5.619e-10 0.34
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.285e-08 0.33
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 5.456e-07 0.31

Nitrofural

DDIT3_HUMAN DDIT3 DNA damage-inducible transcript 3 protein 7.691e-97 0.35
MITF_HUMAN MITF Microphthalmia-associated transcription factor 2.476e-41 0.66
FABH_ECOLI fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.525e-25 0.31
Q86PR3_AEDAE SCP-2 Sterol carrier protein 2 9.841e-25 0.30
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 7.359e-19 0.34
PTN5_HUMAN PTPN5 Tyrosine-protein phosphatase non-receptor type 5 3.331e-16 0.36
O69002_PSEAI pigA Biliverdin-producing heme oxygenase 8.25e-13 0.43
ITF2_HUMAN TCF4 Transcription factor 4 2.492e-12 0.33
MURA_ECOLI murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7.71e-12 0.32
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 3.218e-11 0.52
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 5.074e-11 0.38
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 7.67e-11 0.38
STRP_STRP1 ska Streptokinase A 8.427e-11 0.63
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 3.987e-10 0.58
DUS3_HUMAN DUSP3 Dual specificity protein phosphatase 3 3.433e-09 0.36
TIM23_YEAST TIM23 Mitochondrial import inner membrane translocase subunit TIM23 5e-09 0.60
PTN11_HUMAN PTPN11 Tyrosine-protein phosphatase non-receptor type 11 4.239e-08 0.36
Q8IL32_PLAF7 Heat shock protein 90, putative 1.758e-07 0.42
NR4A1_HUMAN NR4A1 Nuclear receptor subfamily 4 group A member 1 2.636e-06 0.38
CASP6_HUMAN CASP6 Caspase-6 2.652e-06 0.46
MEX5_CAEEL mex-5 Zinc finger protein mex-5 3.017e-06 0.40
PAX8_HUMAN PAX8 Paired box protein Pax-8 4.83e-06 0.48
DNMT1_HUMAN DNMT1 DNA (cytosine-5)-methyltransferase 1 5.061e-06 0.38
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 5.379e-06 0.29
PPBI_MOUSE Iap Intestinal-type alkaline phosphatase 5.854e-06 0.54

Buclizine

CAC1B_RAT Cacna1b Voltage-dependent N-type calcium channel subunit alpha-1B 2.666e-93 0.53
CA2D2_RAT Cacna2d2 Voltage-dependent calcium channel subunit alpha-2/delta-2 2.353e-87 0.49
CACB1_HUMAN CACNB1 Voltage-dependent L-type calcium channel subunit beta-1 2.353e-87 0.49
CACB1_RAT Cacnb1 Voltage-dependent L-type calcium channel subunit beta-1 4.014e-84 0.49
CAC1A_HUMAN CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A 4.736e-79 0.49
AMYP_PIG AMY2 Pancreatic alpha-amylase 4.617e-70 0.37
DRD4_HUMAN DRD4 D(4) dopamine receptor 2.947e-58 0.46
CA2D1_RAT Cacna2d1 Voltage-dependent calcium channel subunit alpha-2/delta-1 2.686e-55 0.47
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 2.383e-46 0.49
SC6A3_RAT Slc6a3 Sodium-dependent dopamine transporter 2.645e-41 0.49
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 2.075e-40 0.33
SGMR1_MOUSE Sigmar1 Sigma non-opioid intracellular receptor 1 1.44e-38 0.44
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 1.82e-37 0.33
O19067_PIG N-methyl-D-aspartate receptor 2.707e-37 0.30
SC6A4_RAT Slc6a4 Sodium-dependent serotonin transporter 1.206e-33 0.49
OPRX_HUMAN OPRL1 Nociceptin receptor 7.314e-33 0.46
SGMR1_CAVPO SIGMAR1 Sigma non-opioid intracellular receptor 1 4.245e-32 0.42
SGMR1_HUMAN SIGMAR1 Sigma non-opioid intracellular receptor 1 1.005e-31 0.55
DRD2_MOUSE Drd2 D(2) dopamine receptor 6.361e-31 0.44
DRD2_HUMAN DRD2 D(2) dopamine receptor 4.25e-27 0.52
B6TK44_MAIZE Cycloeucalenol cycloisomerase 1.85e-25 0.35
DRD1_BOVIN DRD1 D(1A) dopamine receptor 2.36e-24 0.36
ACES_MOUSE Ache Acetylcholinesterase 5.325e-24 0.37
B4FS76_MAIZE 100281352 Delta(14)-sterol reductase 4.351e-23 0.35
Q2TU57_MAIZE Sterol-8,7-isomerase 4.351e-23 0.35
US28_HCMVA US28 G-protein coupled receptor homolog US28 8.996e-23 0.33
ACKR3_HUMAN ACKR3 Atypical chemokine receptor 3 1.321e-22 0.38
CHKA_HUMAN CHKA Choline kinase alpha 2.707e-22 0.37
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.248e-20 0.71
DRD3_HUMAN DRD3 D(3) dopamine receptor 1.43e-19 0.50
FAAH1_HUMAN FAAH Fatty-acid amide hydrolase 1 2.297e-19 0.42
SGMR1_RAT Sigmar1 Sigma non-opioid intracellular receptor 1 3.658e-19 0.38
PA_I000X PA Polymerase acidic protein 6.95e-19 0.36
ACES_ELEEL ache Acetylcholinesterase 2.147e-18 0.45
Q9WTR4_RAT Slc6a2 Transporter 1.658e-17 0.38
LSS_HUMAN LSS Lanosterol synthase 2.401e-17 0.40
CASP5_HUMAN CASP5 Caspase-5 1.11e-16 0.30
DRD3_CHLAE DRD3 D(3) dopamine receptor 1.11e-16 0.33
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.331e-16 0.39
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 3.331e-16 0.32
GP183_HUMAN GPR183 G-protein coupled receptor 183 4.441e-16 0.40
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 7.772e-16 0.68
PA_I34A1 PA Polymerase acidic protein 7.772e-16 0.36
OPRM_HUMAN OPRM1 Mu-type opioid receptor 1.887e-15 0.46
Q8HY88_BOVIN KCNK2 Potassium channel subfamily K member 2 1.998e-15 0.38
MGLL_MOUSE Mgll Monoglyceride lipase 2.554e-15 0.38
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 3.775e-15 0.41
ADA1B_RAT Adra1b Alpha-1B adrenergic receptor 7.105e-15 0.44
5HT2A_PIG HTR2A 5-hydroxytryptamine receptor 2A 1.132e-14 0.33
OPRK_HUMAN OPRK1 Kappa-type opioid receptor 2.109e-14 0.46
HRH3_HUMAN HRH3 Histamine H3 receptor 2.931e-14 0.39
Q9HUN3_PSEAE dnaB Replicative DNA helicase 8.116e-14 0.30
SCN4A_HUMAN SCN4A Sodium channel protein type 4 subunit alpha 2.101e-13 0.31
SC6A3_HUMAN SLC6A3 Sodium-dependent dopamine transporter 4.559e-13 0.44
PGES2_HUMAN PTGES2 Prostaglandin E synthase 2 5.461e-13 0.35
DRD1_PIG DRD1 D(1A) dopamine receptor 7.343e-13 0.37
S6A12_HUMAN SLC6A12 Sodium- and chloride-dependent betaine transporter 1.562e-12 0.31
CCR3_HUMAN CCR3 C-C chemokine receptor type 3 1.795e-12 0.38
SGMR2_RAT Tmem97 Sigma intracellular receptor 2 2.237e-12 0.33
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.171e-12 0.44
ACHP_LYMST Acetylcholine-binding protein 6.254e-12 0.33
SHIP2_HUMAN INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 8.017e-12 0.29
MGLL_HUMAN MGLL Monoglyceride lipase 9.351e-12 0.35
POLK_HUMAN POLK DNA polymerase kappa 1.383e-11 0.28
CA2D1_HUMAN CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 1.402e-11 0.49
PA24A_HUMAN PLA2G4A Cytosolic phospholipase A2 1.644e-11 0.33
CNR1_HUMAN CNR1 Cannabinoid receptor 1 1.832e-11 0.41
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 3.783e-11 0.44
ATP5E_BOVIN ATP5F1E ATP synthase subunit epsilon, mitochondrial 4.248e-11 0.32
ATPB_BOVIN ATP5F1B ATP synthase subunit beta, mitochondrial 4.248e-11 0.32
ATPD_BOVIN ATP5F1D ATP synthase subunit delta, mitochondrial 4.248e-11 0.32
ATPG_BOVIN ATP5F1C ATP synthase subunit gamma, mitochondrial 4.248e-11 0.32
5HT1A_RAT Htr1a 5-hydroxytryptamine receptor 1A 8.057e-11 0.47
MGLL_RAT Mgll Monoglyceride lipase 1.029e-10 0.31
DRD2_CHLAE DRD2 D(2) dopamine receptor 1.241e-10 0.33
CALM_BOVIN CALM Calmodulin 1.309e-10 0.28
CCR9_HUMAN CCR9 C-C chemokine receptor type 9 2.067e-10 0.37
CNR1_RAT Cnr1 Cannabinoid receptor 1 2.49e-10 0.41
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.106e-10 0.28
LAT_MYCTU lat Probable L-lysine-epsilon aminotransferase 3.807e-10 0.30
LOX5_HUMAN ALOX5 Arachidonate 5-lipoxygenase 3.817e-10 0.49
CP19A_RAT Cyp19a1 Aromatase 5.073e-10 0.42
DHCR7_HUMAN DHCR7 7-dehydrocholesterol reductase 5.388e-10 0.29
PDIA1_HUMAN P4HB Protein disulfide-isomerase 6.363e-10 0.32
ACES_HUMAN ACHE Acetylcholinesterase 9.228e-10 0.45
CASP4_HUMAN CASP4 Caspase-4 1.08e-09 0.30
SCN2A_RAT Scn2a Sodium channel protein type 2 subunit alpha 1.083e-09 0.38
ACES_RAT Ache Acetylcholinesterase 1.178e-09 0.45
HRH1_HUMAN HRH1 Histamine H1 receptor 1.245e-09 0.52
RCE1_YEAST RCE1 CAAX prenyl protease 2 1.699e-09 0.38
HRH1_CAVPO HRH1 Histamine H1 receptor 1.796e-09 0.35
OPRD_RAT Oprd1 Delta-type opioid receptor 3.494e-09 0.71
ADA2A_RAT Adra2a Alpha-2A adrenergic receptor 3.532e-09 0.37
GPR6_HUMAN GPR6 G-protein coupled receptor 6 4.224e-09 0.34
DRD2_RAT Drd2 D(2) dopamine receptor 6.509e-09 0.43
Q63380_RAT NET Transporter 1.795e-08 0.37
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 2.082e-08 0.47
S6A13_MOUSE Slc6a13 Sodium- and chloride-dependent GABA transporter 2 2.184e-08 0.31
SC6A4_HUMAN SLC6A4 Sodium-dependent serotonin transporter 2.705e-08 0.42
SC6A2_HUMAN SLC6A2 Sodium-dependent noradrenaline transporter 3.351e-08 0.42
MC4R_HUMAN MC4R Melanocortin receptor 4 7.155e-08 0.41
AL3A1_HUMAN ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1.041e-07 0.31
5HT1A_HUMAN HTR1A 5-hydroxytryptamine receptor 1A 1.462e-07 0.39
CAC1C_CAVPO CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 1.575e-07 0.35
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 1.673e-07 0.44
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 4.028e-07 0.36
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 5.23e-07 0.33
NK1R_HUMAN TACR1 Substance-P receptor 5.376e-07 0.43
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 6.116e-07 0.34
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 6.277e-07 0.34
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 7.41e-07 0.32
HMOX2_RAT Hmox2 Heme oxygenase 2 7.675e-07 0.33
SC6A5_HUMAN SLC6A5 Sodium- and chloride-dependent glycine transporter 2 9.867e-07 0.33
FAAH1_RAT Faah Fatty-acid amide hydrolase 1 1.097e-06 0.42
CAC1B_HUMAN CACNA1B Voltage-dependent N-type calcium channel subunit alpha-1B 1.12e-06 0.38
MPEG1_HUMAN MPEG1 Macrophage-expressed gene 1 protein 1.389e-06 0.29
S6A12_MOUSE Slc6a12 Sodium- and chloride-dependent betaine transporter 1.397e-06 0.31
SC6A3_MOUSE Slc6a3 Sodium-dependent dopamine transporter 1.637e-06 0.28
CCR5_HUMAN CCR5 C-C chemokine receptor type 5 2.031e-06 0.37
5HT2B_HUMAN HTR2B 5-hydroxytryptamine receptor 2B 2.233e-06 0.44
HRH3_RAT Hrh3 Histamine H3 receptor 2.413e-06 0.39
CXCR4_HUMAN CXCR4 C-X-C chemokine receptor type 4 2.443e-06 0.32
OPRM_RAT Oprm1 Mu-type opioid receptor 3.066e-06 0.71
SERA_HUMAN PHGDH D-3-phosphoglycerate dehydrogenase 3.133e-06 0.28
CCR1_HUMAN CCR1 C-C chemokine receptor type 1 3.484e-06 0.34
MDHC_HUMAN MDH1 Malate dehydrogenase, cytoplasmic 4.184e-06 0.30
DCNL1_HUMAN DCUN1D1 DCN1-like protein 1 5.263e-06 0.29
ADA2A_HUMAN ADRA2A Alpha-2A adrenergic receptor 5.416e-06 0.44
HRH2_HUMAN HRH2 Histamine H2 receptor 5.557e-06 0.33
CCR2_HUMAN CCR2 C-C chemokine receptor type 2 6.988e-06 0.36
PCP_MOUSE Prcp Lysosomal Pro-X carboxypeptidase 8.598e-06 0.33
SKN1_CAEEL skn-1 Protein skinhead-1 9.998e-06 0.33

Treprostinil

PI2R_RAT Ptgir Prostacyclin receptor 8.86e-87 0.33
SSR1_RAT Sstr1 Somatostatin receptor type 1 3.524e-62 0.32
SO2A1_HUMAN SLCO2A1 Solute carrier organic anion transporter family member 2A1 6.53e-56 0.33
PI2R_HUMAN PTGIR Prostacyclin receptor 3.342e-52 0.44
PF2R_HUMAN PTGFR Prostaglandin F2-alpha receptor 8.302e-52 0.46
SO2B1_RAT Slco2b1 Solute carrier organic anion transporter family member 2B1 1.021e-47 0.30
SO2A1_MOUSE Slco2a1 Solute carrier organic anion transporter family member 2A1 7.718e-47 0.30
SSR2_RAT Sstr2 Somatostatin receptor type 2 2.308e-46 0.32
PF2R_MOUSE Ptgfr Prostaglandin F2-alpha receptor 3.61e-23 0.33
PF2R_BOVIN PTGFR Prostaglandin F2-alpha receptor 1.113e-22 0.33
GP174_HUMAN GPR174 Probable G-protein coupled receptor 174 1.11e-16 0.28
GPR34_HUMAN GPR34 Probable G-protein coupled receptor 34 3.564e-14 0.28
PD2R_HUMAN PTGDR Prostaglandin D2 receptor 3.73e-14 0.37
PE2R2_HUMAN PTGER2 Prostaglandin E2 receptor EP2 subtype 2.066e-13 0.46
P2Y10_HUMAN P2RY10 Putative P2Y purinoceptor 10 1.423e-12 0.28
SO2A1_RAT Slco2a1 Solute carrier organic anion transporter family member 2A1 2.301e-11 0.32
LPXC_AQUAE lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 9.3e-11 0.29
PE2R1_MOUSE Ptger1 Prostaglandin E2 receptor EP1 subtype 7.173e-09 0.30
PE2R1_HUMAN PTGER1 Prostaglandin E2 receptor EP1 subtype 1.883e-08 0.37
Q6TUJ4_PSEAI blaIMP-1 Metallo beta-lactamase 9.132e-08 0.29
PE2R2_MOUSE Ptger2 Prostaglandin E2 receptor EP2 subtype 2.818e-07 0.30
MTR1B_CHICK Melatonin receptor type 1B 4.905e-07 0.29
PE2R3_HUMAN PTGER3 Prostaglandin E2 receptor EP3 subtype 1.219e-06 0.37
PE2R4_MOUSE Ptger4 Prostaglandin E2 receptor EP4 subtype 1.605e-06 0.30
VACHT_HUMAN SLC18A3 Vesicular acetylcholine transporter 2.192e-06 0.32
PE2R4_HUMAN PTGER4 Prostaglandin E2 receptor EP4 subtype 3.431e-06 0.33

Oxyphencyclimine

AMYP_RAT Amy2 Pancreatic alpha-amylase 7.684e-82 0.41
CP2J2_HUMAN CYP2J2 Cytochrome P450 2J2 8.524e-80 0.35
Q8WMX0_BOVIN Muscarinic receptor M1 1.915e-58 0.32
Q8VH26_CAVPO GPM3 Muscarinic acetylcholine receptor 4.245e-58 0.52
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 5.606e-56 0.52
ABHDB_HUMAN ABHD11 Protein ABHD11 1.035e-55 0.32
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 7.468e-55 0.52
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 8.528e-51 0.52
ACM3_RAT Chrm3 Muscarinic acetylcholine receptor M3 8.576e-47 0.52
ACM2_RAT Chrm2 Muscarinic acetylcholine receptor M2 1.673e-40 0.52
DGLB_MOUSE Daglb Sn1-specific diacylglycerol lipase beta 2.295e-37 0.31
GSTT1_RAT Gstt1 Glutathione S-transferase theta-1 3.56e-37 0.29
PPCE_ELIME f1pep1 Prolyl endopeptidase 3.875e-36 0.29
PPCE_MOUSE Prep Prolyl endopeptidase 1.91e-30 0.29
LYPA2_HUMAN LYPLA2 Acyl-protein thioesterase 2 2.686e-23 0.30
ABHD6_HUMAN ABHD6 Monoacylglycerol lipase ABHD6 3.109e-22 0.31
LYPA1_HUMAN LYPLA1 Acyl-protein thioesterase 1 3.92e-21 0.30
OGRL1_HUMAN OGFRL1 Opioid growth factor receptor-like protein 1 1.109e-20 0.33
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 4.868e-19 0.52
PPCE_BOVIN PREP Prolyl endopeptidase 6.256e-18 0.30
MEN1_HUMAN MEN1 Menin 6.386e-18 0.33
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 2.22e-16 0.52
LUXN_VIBHA luxN Autoinducer 1 sensor kinase/phosphatase LuxN 9.992e-16 0.30
S12A5_RAT Slc12a5 Solute carrier family 12 member 5 9.515e-14 0.31
NMDE2_HUMAN GRIN2B Glutamate receptor ionotropic, NMDA 2B 1.266e-12 0.32
NPY2R_HUMAN NPY2R Neuropeptide Y receptor type 2 1.489e-12 0.34
DGLA_HUMAN DAGLA Sn1-specific diacylglycerol lipase alpha 1.691e-12 0.32
ACES_MOUSE Ache Acetylcholinesterase 5.626e-09 0.32
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 5.69e-08 0.31
ACM4_RAT Chrm4 Muscarinic acetylcholine receptor M4 1.811e-07 0.35
Q8QGU2_CHICK FKBP12.6 Peptidylprolyl isomerase 2.617e-07 0.28
FKB1A_HUMAN FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 5.955e-07 0.32
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.683e-06 0.29
PPCE_HUMAN PREP Prolyl endopeptidase 2.831e-06 0.30
Q8JXU8_9HEPC NS5B RNA-directed RNA polymerase 6.881e-06 0.31
CASP1_MOUSE Casp1 Caspase-1 9.038e-06 0.29

Grepafloxacin

Q47245_ECOLX gyrA DNA gyrase subunit A 4.725e-62 0.52
C3SLN2_ECOLX gyrB DNA gyrase subunit B 9.864e-54 0.52
ACEA_MYCTU icl Isocitrate lyase 9.019e-53 0.41
VATB2_HUMAN ATP6V1B2 V-type proton ATPase subunit B, brain isoform 6.678e-41 0.32
GLYCP_NIPAV G Glycoprotein G 1.5e-32 0.32
DPO3_BACSU polC DNA polymerase III PolC-type 5.048e-22 0.38
PARC_STAAU parC DNA topoisomerase 4 subunit A 5.95e-22 0.53
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 4.774e-15 0.71
GYRA_MYCTU gyrA DNA gyrase subunit A 6.061e-10 0.53
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 1.083e-08 0.31
MAPK3_HUMAN MAPKAPK3 MAP kinase-activated protein kinase 3 3.387e-08 0.39
GYRA_STAAU gyrA DNA gyrase subunit A 5.117e-08 0.52
PARE_STAAU parE DNA topoisomerase 4 subunit B 1.1e-07 0.52
GYRA_ECOLI gyrA DNA gyrase subunit A 6.369e-07 0.52
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 2.282e-06 0.30
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 5.095e-06 0.31

Minoxidil

CASP5_HUMAN CASP5 Caspase-5 1.605e-61 0.38
CASP4_HUMAN CASP4 Caspase-4 1.329e-43 0.38
HRH4_RAT Hrh4 Histamine H4 receptor 2.747e-38 0.46
S100B_HUMAN S100B Protein S100-B 4.289e-11 0.33
HRH4_HUMAN HRH4 Histamine H4 receptor 1.301e-10 0.45
ERM_STREE erm rRNA adenine N-6-methyltransferase 3.598e-09 0.29
CASP1_HUMAN CASP1 Caspase-1 6.387e-07 0.38

Pyrazinamide

Q44079_AERHY cphA2 Beta-lactamase 1.398e-56 0.37
NNMT_HUMAN NNMT Nicotinamide N-methyltransferase 5.226e-48 0.33
HIF1N_HUMAN HIF1AN Hypoxia-inducible factor 1-alpha inhibitor 2.679e-43 0.34
JHD2C_HUMAN JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1.381e-38 0.31
NNMT_MOUSE Nnmt Nicotinamide N-methyltransferase 1.381e-38 0.31
D3ZDM7_RAT Ddo D-aspartate oxidase 2.83e-38 0.30
OXDD_MOUSE Ddo D-aspartate oxidase 2.83e-38 0.30
P4HA1_HUMAN P4HA1 Prolyl 4-hydroxylase subunit alpha-1 1.424e-36 0.31
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 3.311e-29 0.32
P4HA1_RAT P4ha1 Prolyl 4-hydroxylase subunit alpha-1 2.258e-25 0.31
Q7M0F8_CAVPO Protein-glutamine gamma-glutamyltransferase, liver 2.137e-21 0.44
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 3.573e-20 0.32
OXDD_HUMAN DDO D-aspartate oxidase 4.43e-19 0.30
CCNC_HUMAN CCNC Cyclin-C 5.551e-16 0.36
FTO_HUMAN FTO Alpha-ketoglutarate-dependent dioxygenase FTO 5.851e-14 0.34
CDK8_HUMAN CDK8 Cyclin-dependent kinase 8 1.081e-12 0.36
KDM4D_HUMAN KDM4D Lysine-specific demethylase 4D 1.778e-12 0.38
ACHA4_CHICK CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 1.206e-09 0.30
P4HTM_HUMAN P4HTM Transmembrane prolyl 4-hydroxylase 1.697e-09 0.31
MP2K3_HUMAN MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 4.228e-09 0.32
KDM4E_HUMAN KDM4E Lysine-specific demethylase 4E 3.083e-08 0.38
KDM3A_HUMAN KDM3A Lysine-specific demethylase 3A 1.613e-06 0.34

Sucralfate

FGF1_HUMAN FGF1 Fibroblast growth factor 1 3.455e-53 0.46
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.358e-19 0.46

Olanzapine

DRD1_HUMAN DRD1 D(1A) dopamine receptor 1.254e-47 0.79
DRD1_RAT Drd1 D(1A) dopamine receptor 2.513e-33 0.65
HRH4_HUMAN HRH4 Histamine H4 receptor 1.265e-20 0.51
Q39829_SOYBN Lipoxygenase 5.429e-20 0.32
DRD2_RAT Drd2 D(2) dopamine receptor 3.961e-19 0.76
DRD2_HUMAN DRD2 D(2) dopamine receptor 3.51e-18 0.79
DRD2_BOVIN DRD2 D(2) dopamine receptor 1.11e-16 0.76
5HT2C_RAT Htr2c 5-hydroxytryptamine receptor 2C 5.551e-16 0.65
HRH1_RAT Hrh1 Histamine H1 receptor 1.776e-15 0.51
5HT3B_HUMAN HTR3B 5-hydroxytryptamine receptor 3B 2.442e-15 0.29
5HT2A_RAT Htr2a 5-hydroxytryptamine receptor 2A 7.994e-15 0.65
HRH4_RAT Hrh4 Histamine H4 receptor 5.097e-11 0.34
DRD5_HUMAN DRD5 D(1B) dopamine receptor 6.74e-10 0.35
5HT3A_HUMAN HTR3A 5-hydroxytryptamine receptor 3A 5.987e-09 0.32
LOX1_SOYBN LOX1.1 Seed linoleate 13S-lipoxygenase-1 2.015e-08 0.38
DRD4_HUMAN DRD4 D(4) dopamine receptor 3.064e-08 0.65
UPAR_HUMAN PLAUR Urokinase plasminogen activator surface receptor 2.871e-07 0.30
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 2.172e-06 0.60
GLD1_CAEEL gld-1 Female germline-specific tumor suppressor gld-1 3.397e-06 0.32

Tioguanine

GUAD_HUMAN GDA Guanine deaminase 7.456e-46 0.40
PNPH_RAT Pnp Purine nucleoside phosphorylase 7.772e-16 0.41
TGT_ZYMMO tgt Queuine tRNA-ribosyltransferase 3.304e-09 0.31
HPPK_ECOLI folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 1.543e-06 0.49

Ampicillin

BIRC8_HUMAN BIRC8 Baculoviral IAP repeat-containing protein 8 1.731e-44 0.30
BLAC_BACLI penP Beta-lactamase 1.897e-44 0.30
A4ZYU9_ECOLX blaACC-4 Beta-lactamase 1.646e-39 0.49
BLAB_BACCE Metallo-beta-lactamase type 2 4.003e-39 0.44
Q53729_STAAU PBP2 Penicillin-binding protein 2 1.215e-35 0.28
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 2.137e-35 0.38
S15A2_HUMAN SLC15A2 Solute carrier family 15 member 2 1.197e-34 0.43
AMPC_CITFR ampC Beta-lactamase 1.129e-33 0.30
Q3S5C3_SALNE sugE Efflux transporter 1.701e-30 0.49
Q48435_KLEPN bla LAT-2 Beta-lactamase 1.701e-30 0.49
A2RP81_CITFR blaPER-2 Beta-lactamase 1.124e-26 0.60
BIRC2_HUMAN BIRC2 Baculoviral IAP repeat-containing protein 2 1.249e-20 0.32
MA2B1_HUMAN MAN2B1 Lysosomal alpha-mannosidase 9.803e-19 0.30
Q82134_9DELA prt Protease 8.195e-18 0.34
S15A1_HUMAN SLC15A1 Solute carrier family 15 member 1 1.882e-17 0.33
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 1.405e-12 0.43
SOAT1_RAT Soat1 Sterol O-acyltransferase 1 5.319e-12 0.31
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.841e-11 0.30
S22A6_HUMAN SLC22A6 Solute carrier family 22 member 6 3.166e-11 0.43
CATL1_RAT Ctsl Cathepsin L1 2.583e-10 0.31
AMPC_ECOLI ampC Beta-lactamase 3.94e-10 0.48
S22AB_HUMAN SLC22A11 Solute carrier family 22 member 11 9.855e-10 0.30
CDC42_HUMAN CDC42 Cell division control protein 42 homolog 2.72e-09 0.29
Q5A7N4_CANAL TPT1 tRNA 2'-phosphotransferase 4.975e-09 0.30
BLAC_STAAU blaZ Beta-lactamase 9.758e-09 0.32
Q82323_9DELA Protease 8.292e-07 0.33
S22A8_HUMAN SLC22A8 Solute carrier family 22 member 8 3.213e-06 0.30

Cidofovir

HPRT_HUMAN HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3.021e-43 0.46
DPOLB_HUMAN POLB DNA polymerase beta 4.81e-20 0.33
TYPH_RAT Tymp Thymidine phosphorylase 4.879e-19 0.34
RNAS1_BOVIN RNASE1 Ribonuclease pancreatic 8.882e-15 0.37
DPOG1_HUMAN POLG DNA polymerase subunit gamma-1 7.901e-12 0.32
O39930_9HEPC NS5b RNA-directed RNA polymerase 3.57e-11 0.32
V5TFZ2_9FLAV Nonstructural protein 5 6.023e-11 0.29
TYPH_HUMAN TYMP Thymidine phosphorylase 4.265e-10 0.51
SIAT1_HUMAN ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 8.128e-07 0.34
C3TDZ2_ECOLX fabH 3-oxoacyl-[acyl-carrier-protein] synthase 3 1.049e-06 0.35

Calcium_glucoheptonate

Q9GRG6_9TRYP 6pgl 6-phosphogluconolactonase 5.166e-42 0.33
LUXP_VIBHA luxP Autoinducer 2-binding periplasmic protein LuxP 1.166e-06 0.28
MGA_HUMAN MGAM Maltase-glucoamylase, intestinal 2.85e-06 0.29

Carbimazole

PIN4_HUMAN PIN4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 3.458e-38 0.30
WRN_HUMAN WRN Werner syndrome ATP-dependent helicase 1.517e-10 0.31
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 1.863e-09 0.30
PVDQ_PSEAE pvdQ Acyl-homoserine lactone acylase PvdQ 5.262e-07 0.31

Protriptyline

KCNK2_RAT Kcnk2 Potassium channel subfamily K member 2 2.435e-37 0.30
ANM6_HUMAN PRMT6 Protein arginine N-methyltransferase 6 5.06e-28 0.32
CARM1_HUMAN CARM1 Histone-arginine methyltransferase CARM1 2.537e-23 0.32
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 2.84e-08 0.33
S22A1_RAT Slc22a1 Solute carrier family 22 member 1 2.648e-07 0.33
Q9WTR4_RAT Slc6a2 Transporter 4.484e-07 0.33
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 3.267e-06 0.33

Clobazam

PRIO_MOUSE Prnp Major prion protein 3.875e-36 0.29
Q76129_9HIV1 gag Structural capsid protein 5.459e-32 0.38
PPOC_ORYSJ PPOX1 Protoporphyrinogen oxidase, chloroplastic 5.81e-27 0.33
PD2R2_MOUSE Ptgdr2 Prostaglandin D2 receptor 2 5.909e-25 0.32
CATG_HUMAN CTSG Cathepsin G 3.195e-18 0.35
PDR5_YEAST PDR5 Pleiotropic ABC efflux transporter of multiple drugs 4.158e-18 0.29
KAPCA_RAT Prkaca cAMP-dependent protein kinase catalytic subunit alpha 1.11e-16 0.31
NLRP1_HUMAN NLRP1 NACHT, LRR and PYD domains-containing protein 1 3.331e-16 0.36
AADAT_RAT Aadat Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 6.661e-16 0.29
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6.661e-16 0.35
B2LA1_MOUSE Bcl2a1 Bcl-2-related protein A1 1.779e-13 0.35
A0A060INS8_CAPHI CTSH Cathepsin H 1.941e-13 0.33
CTRA_BOVIN Chymotrypsinogen A 2.301e-11 0.35
CALM_BOVIN CALM Calmodulin 1.105e-10 0.29
B2LA1_HUMAN BCL2A1 Bcl-2-related protein A1 6.299e-10 0.34
CAC1D_RAT Cacna1d Voltage-dependent L-type calcium channel subunit alpha-1D 2.114e-09 0.30
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 3.304e-09 0.31
KCNK2_HUMAN KCNK2 Potassium channel subfamily K member 2 3.598e-09 0.29
AL1A1_HUMAN ALDH1A1 Retinal dehydrogenase 1 4.148e-09 0.35
DHB3_HUMAN HSD17B3 Testosterone 17-beta-dehydrogenase 3 1.467e-08 0.33
CALM1_HUMAN CALM1 Calmodulin-1 3.985e-08 0.29
KPCG_RAT Prkcg Protein kinase C gamma type 6.502e-08 0.31
NOX4_HUMAN NOX4 NADPH oxidase 4 1.189e-07 0.33
REV_HV1H2 rev Protein Rev 2.725e-07 0.28
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.146e-07 0.29
RT109_YEAST RTT109 Histone acetyltransferase RTT109 6.721e-07 0.33
CMA1_HUMAN CMA1 Chymase 6.81e-07 0.35
NOX1_HUMAN NOX1 NADPH oxidase 1 8.55e-07 0.33
Q9FYV8_MAIZE Protoporphyrinogen oxidase 8.825e-07 0.33
TYTR_TRYCR TPR Trypanothione reductase 9.218e-07 0.30
RAD51_HUMAN RAD51 DNA repair protein RAD51 homolog 1 6.347e-06 0.29
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 7.398e-06 0.28
SC6A4_MOUSE Slc6a4 Sodium-dependent serotonin transporter 7.679e-06 0.30
DPOL_VACCW POL DNA polymerase 7.85e-06 0.28
AADAT_HUMAN AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 8.822e-06 0.29
ALDH2_HUMAN ALDH2 Aldehyde dehydrogenase, mitochondrial 9.852e-06 0.35

Metocurine_iodide

ACHA2_HUMAN CHRNA2 Neuronal acetylcholine receptor subunit alpha-2 2.83e-34 0.56
ACHB4_MOUSE Chrnb4 Neuronal acetylcholine receptor subunit beta-4 4.652e-14 0.33
ACHB2_MOUSE Chrnb2 Neuronal acetylcholine receptor subunit beta-2 3.688e-13 0.33
ACHA_TETCF CHRNA1 Acetylcholine receptor subunit alpha 3.1e-11 0.62
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 7.601e-10 0.62
PDE1A_HUMAN PDE1A Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 5.93e-09 0.49
KCNN3_RAT Kcnn3 Small conductance calcium-activated potassium channel protein 3 1.244e-06 0.62
A9XFY4_MUSDO nAChRalpha5 Nicotinic acetylcholine receptor alpha 5 subunit 1.353e-06 0.62

Doxylamine

ERR3_MOUSE Esrrg Estrogen-related receptor gamma 1.892e-30 0.30
AMYP_RAT Amy2 Pancreatic alpha-amylase 1.054e-28 0.33
ERR3_HUMAN ESRRG Estrogen-related receptor gamma 4.46e-26 0.31
ATP6_MYCTU atpB ATP synthase subunit a 3.96e-17 0.30
ATPA_MYCTU atpA ATP synthase subunit alpha 3.96e-17 0.30
ATPB_MYCTU atpD ATP synthase subunit beta 3.96e-17 0.30
ATPE_MYCTU atpC ATP synthase epsilon chain 3.96e-17 0.30
ATPFD_MYCTU atpFH ATP synthase subunit b-delta 3.96e-17 0.30
ATPF_MYCTU atpF ATP synthase subunit b 3.96e-17 0.30
ATPG_MYCTU atpG ATP synthase gamma chain 3.96e-17 0.30
ATPL_MYCTU atpE ATP synthase subunit c 3.96e-17 0.30
ACM4_HUMAN CHRM4 Muscarinic acetylcholine receptor M4 8.882e-15 0.47
ACM5_HUMAN CHRM5 Muscarinic acetylcholine receptor M5 1.688e-14 0.47
Q8WMX0_BOVIN Muscarinic receptor M1 9.516e-13 0.31
ERR2_HUMAN ESRRB Steroid hormone receptor ERR2 1.842e-12 0.30
ACM2_HUMAN CHRM2 Muscarinic acetylcholine receptor M2 2.196e-11 0.47
ACM1_HUMAN CHRM1 Muscarinic acetylcholine receptor M1 3.458e-10 0.47
ACM3_HUMAN CHRM3 Muscarinic acetylcholine receptor M3 6.637e-10 0.47
5HT2B_RAT Htr2b 5-hydroxytryptamine receptor 2B 1.01e-08 0.33
ACM1_DROME mAChR-A Muscarinic acetylcholine receptor DM1 3.541e-08 0.32
ACV1B_HUMAN ACVR1B Activin receptor type-1B 4.514e-08 0.34
HRH1_HUMAN HRH1 Histamine H1 receptor 4.175e-07 0.38
C11B1_BOVIN CYP11B1 Cytochrome P450 11B1, mitochondrial 5.217e-07 0.30
NORA_STAAU norA Quinolone resistance protein NorA 2.942e-06 0.30

Omeprazole

TGT_HUMAN QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 7.193e-24 0.29
I23O2_MOUSE Ido2 Indoleamine 2,3-dioxygenase 2 1.143e-21 0.42
TBB2B_BOVIN TUBB2B Tubulin beta-2B chain 1.443e-15 0.32
GSTO1_HUMAN GSTO1 Glutathione S-transferase omega-1 1.532e-14 0.63
PGFRA_MOUSE Pdgfra Platelet-derived growth factor receptor alpha 1.112e-12 0.31
PEBB_HUMAN CBFB Core-binding factor subunit beta 4.663e-12 0.30
TRAP1_HUMAN TRAP1 Heat shock protein 75 kDa, mitochondrial 1.537e-11 0.33
DDAH1_HUMAN DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 1.577e-11 0.42
LUCI_RENRE Coelenterazine h 2-monooxygenase 5.058e-08 0.28
LPAR3_HUMAN LPAR3 Lysophosphatidic acid receptor 3 6.444e-08 0.29
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.077e-07 0.62
TBB1_HUMAN TUBB1 Tubulin beta-1 chain 2.335e-06 0.32
ENPL_CANLF HSP90B1 Endoplasmin 4.303e-06 0.33
DPOL_VACCW POL DNA polymerase 4.478e-06 0.30
S22A2_HUMAN SLC22A2 Solute carrier family 22 member 2 4.563e-06 0.35
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 8.242e-06 0.34
S47A1_HUMAN SLC47A1 Multidrug and toxin extrusion protein 1 8.708e-06 0.35

Dexrazoxane

A4TVL0_9PROT Cereblon isoform 4 2.847e-23 0.29

Ethambutol

Q6UB75_PIG Group VII phospholipase A2 2.163e-09 0.39

Secobarbital

MTP_BOVIN MTTP Microsomal triglyceride transfer protein large subunit 3.629e-07 0.29

Trimethadione

PRTN3_HUMAN PRTN3 Myeloblastin 1.44e-06 0.37

Carisoprodol

CATH_HUMAN CTSH Pro-cathepsin H 4.618e-06 0.32
CATK_HUMAN CTSK Cathepsin K 5.2e-06 0.35