Results of Job: search_98df702c-587b-4ff9-a814-c004101744e2

Query Target Key Target Name Description P-Value MaxTC

compound_1

IKKE_HUMAN IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2.84e-166 0.51
TBK1_HUMAN TBK1 Serine/threonine-protein kinase TBK1 2.466e-150 0.51
SMG1_HUMAN SMG1 Serine/threonine-protein kinase SMG1 4.222e-138 0.53
CCND2_HUMAN CCND2 G1/S-specific cyclin-D2 1.337e-131 0.42
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 9.354e-109 0.48
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 6.085e-96 0.42
CDK4_HUMAN CDK4 Cyclin-dependent kinase 4 2.737e-84 0.50
CCND3_HUMAN CCND3 G1/S-specific cyclin-D3 4.408e-68 0.42
CDK6_HUMAN CDK6 Cyclin-dependent kinase 6 7.194e-67 0.41
KSYK_HUMAN SYK Tyrosine-protein kinase SYK 6.338e-65 0.46
DKK1_HUMAN DKK1 Dickkopf-related protein 1 4.013e-53 0.38
CCNB1_HUMAN CCNB1 G2/mitotic-specific cyclin-B1 8.74e-51 0.48
MK10_HUMAN MAPK10 Mitogen-activated protein kinase 10 2.142e-47 0.54
SYK_HUMAN KARS1 Lysine--tRNA ligase 5.76e-47 0.38
JAK3_MOUSE Jak3 Tyrosine-protein kinase JAK3 3.345e-44 0.37
KPCD1_HUMAN PRKD1 Serine/threonine-protein kinase D1 1.159e-43 0.38
CDK2_HUMAN CDK2 Cyclin-dependent kinase 2 1.632e-42 0.50
MAPK5_HUMAN MAPKAPK5 MAP kinase-activated protein kinase 5 1.371e-41 0.39
IKKB_HUMAN IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 4.073e-41 0.53
CCNA2_HUMAN CCNA2 Cyclin-A2 4.541e-41 0.48
IKKA_HUMAN CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha 2.116e-40 0.45
CCNE2_HUMAN CCNE2 G1/S-specific cyclin-E2 2.779e-36 0.41
HRH1_MOUSE Hrh1 Histamine H1 receptor 1.097e-35 0.28
CCNH_HUMAN CCNH Cyclin-H 1.569e-35 0.40
CDK7_HUMAN CDK7 Cyclin-dependent kinase 7 6.863e-33 0.49
ZAP70_HUMAN ZAP70 Tyrosine-protein kinase ZAP-70 9.045e-32 0.46
NEMO_HUMAN IKBKG NF-kappa-B essential modulator 1.097e-31 0.30
CDK1_HUMAN CDK1 Cyclin-dependent kinase 1 3.831e-31 0.48
ACVR1_HUMAN ACVR1 Activin receptor type-1 5.743e-31 0.50
CCNB2_HUMAN CCNB2 G2/mitotic-specific cyclin-B2 1.815e-30 0.40
CCNB3_HUMAN CCNB3 G2/mitotic-specific cyclin-B3 1.815e-30 0.40
CCNA1_HUMAN CCNA1 Cyclin-A1 4.841e-30 0.48
BMR1A_HUMAN BMPR1A Bone morphogenetic protein receptor type-1A 9.318e-30 0.50
PK3CA_HUMAN PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 8.422e-29 0.41
JUN_HUMAN JUN Transcription factor AP-1 1.81e-28 0.48
MTOR_HUMAN MTOR Serine/threonine-protein kinase mTOR 4.849e-27 0.45
RIPK1_MOUSE Ripk1 Receptor-interacting serine/threonine-protein kinase 1 6.018e-27 0.35
EPHB4_HUMAN EPHB4 Ephrin type-B receptor 4 9.474e-27 0.42
BMP4_MOUSE Bmp4 Bone morphogenetic protein 4 1.989e-26 0.32
CD63_HUMAN CD63 CD63 antigen 2.278e-26 0.36
ACVR1_MOUSE Acvr1 Activin receptor type-1 2.362e-26 0.33
HIPK1_HUMAN HIPK1 Homeodomain-interacting protein kinase 1 8.807e-26 0.37
JAK3_HUMAN JAK3 Tyrosine-protein kinase JAK3 1.239e-23 0.59
Q0GMK6_RABIT CDK4 Cyclin-dependent kinase 4 9.436e-23 0.33
MP2K1_MOUSE Map2k1 Dual specificity mitogen-activated protein kinase kinase 1 9.993e-23 0.36
JAK2_HUMAN JAK2 Tyrosine-protein kinase JAK2 1.018e-22 0.62
BCR_HUMAN BCR Breakpoint cluster region protein 7.766e-22 0.35
KPCD2_HUMAN PRKD2 Serine/threonine-protein kinase D2 2.343e-20 0.46
IGF1R_HUMAN IGF1R Insulin-like growth factor 1 receptor 2.792e-20 0.47
JAK2_MOUSE Jak2 Tyrosine-protein kinase JAK2 6.172e-20 0.50
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 6.439e-20 0.54
MK10_RAT Mapk10 Mitogen-activated protein kinase 10 7.643e-20 0.54
PK3CG_HUMAN PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 7.968e-20 0.37
FAK1_HUMAN PTK2 Focal adhesion kinase 1 5.412e-19 0.47
BMP4_HUMAN BMP4 Bone morphogenetic protein 4 8.843e-18 0.33
DYR1B_HUMAN DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1.333e-17 0.47
MTOR_RAT Mtor Serine/threonine-protein kinase mTOR 4.96e-17 0.36
CDK9_HUMAN CDK9 Cyclin-dependent kinase 9 5.106e-17 0.49
BMR1B_HUMAN BMPR1B Bone morphogenetic protein receptor type-1B 5.413e-17 0.50
CCNT1_HUMAN CCNT1 Cyclin-T1 5.422e-17 0.49
LCK_HUMAN LCK Tyrosine-protein kinase Lck 1.11e-16 0.46
MK09_HUMAN MAPK9 Mitogen-activated protein kinase 9 1.11e-16 0.54
YES_HUMAN YES1 Tyrosine-protein kinase Yes 1.11e-16 0.41
ACK1_HUMAN TNK2 Activated CDC42 kinase 1 2.22e-16 0.47
CCNE1_HUMAN CCNE1 G1/S-specific cyclin-E1 1.443e-15 0.47
BPTF_HUMAN BPTF Nucleosome-remodeling factor subunit BPTF 1.776e-15 0.29
KCC2D_HUMAN CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 5.107e-15 0.49
BRAF_HUMAN BRAF Serine/threonine-protein kinase B-raf 6.217e-15 0.37
BMPR2_HUMAN BMPR2 Bone morphogenetic protein receptor type-2 1.188e-14 0.33
KSYK_RAT Syk Tyrosine-protein kinase SYK 1.832e-14 0.40
SRC_HUMAN SRC Proto-oncogene tyrosine-protein kinase Src 2.054e-14 0.46
ABL1_HUMAN ABL1 Tyrosine-protein kinase ABL1 3.053e-14 0.47
INSR_HUMAN INSR Insulin receptor 4.141e-14 0.46
NK2R_MESAU TACR2 Substance-K receptor 5.063e-14 0.33
PMYT1_HUMAN PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5.296e-14 0.39
WEE1_HUMAN WEE1 Wee1-like protein kinase 5.862e-14 0.47
FLT3_HUMAN FLT3 Receptor-type tyrosine-protein kinase FLT3 1.403e-13 0.53
CHK1_HUMAN CHEK1 Serine/threonine-protein kinase Chk1 2.079e-13 0.47
KIT_MOUSE Kit Mast/stem cell growth factor receptor Kit 2.581e-13 0.40
CLK2_HUMAN CLK2 Dual specificity protein kinase CLK2 3.364e-13 0.47
ABL1_MOUSE Abl1 Tyrosine-protein kinase ABL1 4.11e-13 0.30
MAPK2_HUMAN MAPKAPK2 MAP kinase-activated protein kinase 2 4.416e-13 0.35
Q9HUN3_PSEAE dnaB Replicative DNA helicase 4.673e-13 0.28
LTK_HUMAN LTK Leukocyte tyrosine kinase receptor 4.736e-13 0.47
PGFRA_HUMAN PDGFRA Platelet-derived growth factor receptor alpha 6.63e-13 0.53
AURKA_HUMAN AURKA Aurora kinase A 8.905e-13 0.50
TTK_HUMAN TTK Dual specificity protein kinase TTK 1.194e-12 0.36
TAOK1_HUMAN TAOK1 Serine/threonine-protein kinase TAO1 1.59e-12 0.47
ALK_HUMAN ALK ALK tyrosine kinase receptor 1.604e-12 0.47
RET_HUMAN RET Proto-oncogene tyrosine-protein kinase receptor Ret 4.525e-12 0.47
M4K5_HUMAN MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 6.199e-12 0.47
PAK1_HUMAN PAK1 Serine/threonine-protein kinase PAK 1 8.649e-12 0.41
O96526_LEIMA CRK3 Cdc2-related kinase 9.793e-12 0.35
CLK4_HUMAN CLK4 Dual specificity protein kinase CLK4 1.037e-11 0.47
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 1.374e-11 0.39
ACV1B_HUMAN ACVR1B Activin receptor type-1B 1.851e-11 0.33
MP2K2_HUMAN MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 2.511e-11 0.47
FYN_HUMAN FYN Tyrosine-protein kinase Fyn 3.034e-11 0.47
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 3.058e-11 0.42
GSK3B_RAT Gsk3b Glycogen synthase kinase-3 beta 3.542e-11 0.32
MTOR_MOUSE Mtor Serine/threonine-protein kinase mTOR 7.011e-11 0.30
TBK1_MOUSE Tbk1 Serine/threonine-protein kinase TBK1 7.183e-11 0.33
GSK3B_HUMAN GSK3B Glycogen synthase kinase-3 beta 8.754e-11 0.46
FGFR1_HUMAN FGFR1 Fibroblast growth factor receptor 1 1.246e-10 0.47
VGFR1_HUMAN FLT1 Vascular endothelial growth factor receptor 1 2.307e-10 0.53
VGFR2_HUMAN KDR Vascular endothelial growth factor receptor 2 2.308e-10 0.53
KPCD3_HUMAN PRKD3 Serine/threonine-protein kinase D3 2.733e-10 0.47
CLK3_HUMAN CLK3 Dual specificity protein kinase CLK3 3.194e-10 0.30
TGFR1_HUMAN TGFBR1 TGF-beta receptor type-1 3.822e-10 0.50
RON_HUMAN MST1R Macrophage-stimulating protein receptor 3.891e-10 0.47
KCC2A_HUMAN CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha 4.705e-10 0.46
CLK1_HUMAN CLK1 Dual specificity protein kinase CLK1 4.955e-10 0.39
AURKB_HUMAN AURKB Aurora kinase B 6.099e-10 0.50
M4K4_HUMAN MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 6.468e-10 0.46
PDE10_RAT Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 6.858e-10 0.33
KS6A3_MOUSE Rps6ka3 Ribosomal protein S6 kinase alpha-3 7.375e-10 0.34
MELK_HUMAN MELK Maternal embryonic leucine zipper kinase 9.432e-10 0.35
RAC1_HUMAN RAC1 Ras-related C3 botulinum toxin substrate 1 1.072e-09 0.28
M4K2_HUMAN MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1.185e-09 0.47
AOC3_HUMAN AOC3 Membrane primary amine oxidase 1.707e-09 0.32
NEK2_HUMAN NEK2 Serine/threonine-protein kinase Nek2 2.193e-09 0.47
PDGFB_HUMAN PDGFB Platelet-derived growth factor subunit B 2.27e-09 0.51
NMT_ASPFU nmt1 Glycylpeptide N-tetradecanoyltransferase 2.485e-09 0.29
ROCK1_HUMAN ROCK1 Rho-associated protein kinase 1 3.08e-09 0.47
S47A2_HUMAN SLC47A2 Multidrug and toxin extrusion protein 2 3.247e-09 0.29
ERBB2_HUMAN ERBB2 Receptor tyrosine-protein kinase erbB-2 3.32e-09 0.43
KIT_HUMAN KIT Mast/stem cell growth factor receptor Kit 4.403e-09 0.53
PK3CB_HUMAN PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 4.997e-09 0.37
FAK2_HUMAN PTK2B Protein-tyrosine kinase 2-beta 6.168e-09 0.34
DAPK3_HUMAN DAPK3 Death-associated protein kinase 3 6.509e-09 0.47
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 7.232e-09 0.41
DYR1A_HUMAN DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 8.4e-09 0.47
PAK4_HUMAN PAK4 Serine/threonine-protein kinase PAK 4 9.86e-09 0.47
TLR9_HUMAN TLR9 Toll-like receptor 9 1.144e-08 0.32
PAK3_HUMAN PAK3 Serine/threonine-protein kinase PAK 3 1.221e-08 0.29
AAPK1_HUMAN PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 1.324e-08 0.47
M3K20_HUMAN MAP3K20 Mitogen-activated protein kinase kinase kinase 20 1.367e-08 0.46
PGFRB_HUMAN PDGFRB Platelet-derived growth factor receptor beta 1.854e-08 0.53
PK3C3_HUMAN PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 2.041e-08 0.30
SRMS_HUMAN SRMS Tyrosine-protein kinase Srms 2.688e-08 0.36
LRRK2_HUMAN LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 2.738e-08 0.47
ACVL1_HUMAN ACVRL1 Serine/threonine-protein kinase receptor R3 3.574e-08 0.33
MARK4_HUMAN MARK4 MAP/microtubule affinity-regulating kinase 4 4.776e-08 0.31
STK3_HUMAN STK3 Serine/threonine-protein kinase 3 5.47e-08 0.46
O97467_PLAFA ht1 Hexose transporter 1 6.454e-08 0.40
NTRK2_HUMAN NTRK2 BDNF/NT-3 growth factors receptor 7.016e-08 0.47
KS6A3_HUMAN RPS6KA3 Ribosomal protein S6 kinase alpha-3 7.076e-08 0.47
TYRO3_HUMAN TYRO3 Tyrosine-protein kinase receptor TYRO3 7.221e-08 0.47
MARK3_HUMAN MARK3 MAP/microtubule affinity-regulating kinase 3 7.305e-08 0.46
PIM3_HUMAN PIM3 Serine/threonine-protein kinase pim-3 7.69e-08 0.39
PAK2_HUMAN PAK2 Serine/threonine-protein kinase PAK 2 7.724e-08 0.29
PIM1_HUMAN PIM1 Serine/threonine-protein kinase pim-1 8.137e-08 0.39
KPCA_HUMAN PRKCA Protein kinase C alpha type 8.318e-08 0.35
AAKB1_HUMAN PRKAB1 5'-AMP-activated protein kinase subunit beta-1 9.689e-08 0.33
TYK2_HUMAN TYK2 Non-receptor tyrosine-protein kinase TYK2 1.166e-07 0.53
TGFR2_HUMAN TGFBR2 TGF-beta receptor type-2 1.231e-07 0.33
KC1A_HUMAN CSNK1A1 Casein kinase I isoform alpha 1.417e-07 0.47
P85A_HUMAN PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha 1.478e-07 0.34
CSF1R_HUMAN CSF1R Macrophage colony-stimulating factor 1 receptor 1.978e-07 0.47
AVR2B_HUMAN ACVR2B Activin receptor type-2B 2.532e-07 0.34
PGFRB_MOUSE Pdgfrb Platelet-derived growth factor receptor beta 2.717e-07 0.39
ERBB4_HUMAN ERBB4 Receptor tyrosine-protein kinase erbB-4 2.902e-07 0.41
CDK19_HUMAN CDK19 Cyclin-dependent kinase 19 2.971e-07 0.40
MP2K1_HUMAN MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 3.028e-07 0.47
ROS1_HUMAN ROS1 Proto-oncogene tyrosine-protein kinase ROS 3.081e-07 0.46
M3K7_HUMAN MAP3K7 Mitogen-activated protein kinase kinase kinase 7 3.208e-07 0.35
O61059_LEIME LmGT2 Glucose transporter 4.719e-07 0.40
EGFR_HUMAN EGFR Epidermal growth factor receptor 5.539e-07 0.46
HIPK4_HUMAN HIPK4 Homeodomain-interacting protein kinase 4 5.755e-07 0.46
BRSK2_HUMAN BRSK2 Serine/threonine-protein kinase BRSK2 5.944e-07 0.33
FRK_HUMAN FRK Tyrosine-protein kinase FRK 7.594e-07 0.46
MAT1_HUMAN MNAT1 CDK-activating kinase assembly factor MAT1 9.911e-07 0.32
NTRK3_HUMAN NTRK3 NT-3 growth factor receptor 1.082e-06 0.46
GTR1_HUMAN SLC2A1 Solute carrier family 2, facilitated glucose transporter member 1 1.123e-06 0.40
MK07_HUMAN MAPK7 Mitogen-activated protein kinase 7 1.172e-06 0.30
BTK_HUMAN BTK Tyrosine-protein kinase BTK 1.222e-06 0.47
SLK_HUMAN SLK STE20-like serine/threonine-protein kinase 1.8e-06 0.46
VGFR2_MOUSE Kdr Vascular endothelial growth factor receptor 2 2.342e-06 0.30
CDC7_HUMAN CDC7 Cell division cycle 7-related protein kinase 3.444e-06 0.46
PK3CD_HUMAN PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.729e-06 0.34
AURKC_HUMAN AURKC Aurora kinase C 3.858e-06 0.46
GSK3A_HUMAN GSK3A Glycogen synthase kinase-3 alpha 4.102e-06 0.46
PHKG2_HUMAN PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 4.658e-06 0.46
LUCI_AQULA Luciferin 4-monooxygenase 5.327e-06 0.29
FER_HUMAN FER Tyrosine-protein kinase Fer 5.363e-06 0.46
DPOL_VACCW POL DNA polymerase 5.68e-06 0.29
BLK_HUMAN BLK Tyrosine-protein kinase Blk 6.494e-06 0.46
ADK_RAT Adk Adenosine kinase 7.416e-06 0.32
PKN2_HUMAN PKN2 Serine/threonine-protein kinase N2 7.646e-06 0.47
MK14_HUMAN MAPK14 Mitogen-activated protein kinase 14 7.659e-06 0.35
MK01_HUMAN MAPK1 Mitogen-activated protein kinase 1 9.183e-06 0.43