Results of Job: search_a02942a5-512f-4ccf-94d1-5dacb79fe277

Query Target Key Target Name Description P-Value MaxTC

compound_1

DYR_BOVIN DHFR Dihydrofolate reductase 4.918e-142 0.61
PLPL6_MOUSE Pnpla6 Neuropathy target esterase 7.957e-84 0.40
ABHD6_MOUSE Abhd6 Monoacylglycerol lipase ABHD6 3.506e-70 0.40
MGLL_MOUSE Mgll Monoglyceride lipase 9.09e-58 0.40
TGM2_CAVCU TGM2 Protein-glutamine gamma-glutamyltransferase 2 3.699e-56 0.32
AGTR1_RABIT AGTR1 Type-1 angiotensin II receptor 1.755e-52 0.44
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 2.83e-51 0.37
AGTR2_RAT Agtr2 Type-2 angiotensin II receptor 6.971e-43 0.44
PPBT_BOVIN ALPL Alkaline phosphatase, tissue-nonspecific isozyme 8.886e-39 0.43
PKR2_HUMAN PROKR2 Prokineticin receptor 2 9.406e-37 0.29
UBE2B_HUMAN UBE2B Ubiquitin-conjugating enzyme E2 B 1.007e-35 0.28
PORCN_MOUSE Porcn Protein-serine O-palmitoleoyltransferase porcupine 6.488e-32 0.36
FAAH1_MOUSE Faah Fatty-acid amide hydrolase 1 3.799e-31 0.40
PDE10_MOUSE Pde10a cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1.023e-29 0.33
MCL1_MOUSE Mcl1 Induced myeloid leukemia cell differentiation protein Mcl-1 homolog 1.545e-29 0.31
NMDE4_RAT Grin2d Glutamate receptor ionotropic, NMDA 2D 2.339e-29 0.40
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 4.732e-29 0.42
RASH_HUMAN HRAS GTPase HRas 3.349e-26 0.36
AL5AP_RAT Alox5ap Arachidonate 5-lipoxygenase-activating protein 6.278e-26 0.32
PA2GA_HUMAN PLA2G2A Phospholipase A2, membrane associated 1.207e-25 0.37
WNK1_HUMAN WNK1 Serine/threonine-protein kinase WNK1 7.863e-25 0.34
Q4DCQ3_TRYCC Superoxide dismutase 8.943e-25 0.30
DPOL_HHV6U U38 DNA polymerase catalytic subunit 1.213e-24 0.35
CP3A4_HUMAN CYP3A4 Cytochrome P450 3A4 8.831e-24 0.51
PPBI_BOVIN ALPI Intestinal-type alkaline phosphatase 6.928e-23 0.43
EXSA_PSEAE exsA Exoenzyme S synthesis regulatory protein ExsA 6.543e-22 0.34
ABCG2_HUMAN ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 7.691e-22 0.39
PKR1_HUMAN PROKR1 Prokineticin receptor 1 8.418e-22 0.34
CP2C9_HUMAN CYP2C9 Cytochrome P450 2C9 1.07e-20 0.51
NPBW1_HUMAN NPBWR1 Neuropeptides B/W receptor type 1 1.414e-20 0.33
CFTR_HUMAN CFTR Cystic fibrosis transmembrane conductance regulator 1.704e-20 0.39
GNRHR_HUMAN GNRHR Gonadotropin-releasing hormone receptor 1.973e-20 0.42
ALDR_RAT Akr1b1 Aldo-keto reductase family 1 member B1 2.504e-20 0.35
AL5AP_HUMAN ALOX5AP Arachidonate 5-lipoxygenase-activating protein 4.287e-20 0.34
PANC_MYCTU panC Pantothenate synthetase 1.024e-18 0.39
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 1.046e-18 0.38
PRIO_HUMAN PRNP Major prion protein 2.004e-18 0.46
O31272_9GAMM imiS Beta-lactamase 2.929e-18 0.30
GLUT4_HUMAN SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 4.879e-18 0.29
CMA1_RAT Cma1 Chymase 7.088e-18 0.28
MCPT9_MOUSE Mcpt9 Mast cell protease 9 7.088e-18 0.28
SETD7_HUMAN SETD7 Histone-lysine N-methyltransferase SETD7 1.477e-17 0.29
CP2CJ_HUMAN CYP2C19 Cytochrome P450 2C19 3.199e-17 0.42
APJ_HUMAN APLNR Apelin receptor 1.11e-16 0.31
NMDE3_RAT Grin2c Glutamate receptor ionotropic, NMDA 2C 1.11e-16 0.40
STXA_SHIDY stxA Shiga toxin subunit A 1.11e-16 0.31
HIS1_MYCTU hisG ATP phosphoribosyltransferase 3.331e-16 0.36
S29A1_HUMAN SLC29A1 Equilibrative nucleoside transporter 1 9.992e-16 0.36
AA3R_HUMAN ADORA3 Adenosine receptor A3 1.11e-15 0.36
TYDP1_HUMAN TDP1 Tyrosyl-DNA phosphodiesterase 1 1.443e-15 0.34
TYSY_MOUSE Tyms Thymidylate synthase 1.554e-15 0.33
C4YTQ8_CANAW ATP-dependent molecular chaperone HSP82 2.331e-15 0.45
ISPD_ARATH ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic 6.55e-15 0.28
CD5R1_HUMAN CDK5R1 Cyclin-dependent kinase 5 activator 1 1.843e-14 0.35
RHOA_HUMAN RHOA Transforming protein RhoA 2.487e-14 0.31
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 2.787e-14 0.33
GP139_HUMAN GPR139 Probable G-protein coupled receptor 139 3.031e-14 0.32
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 3.042e-14 0.35
ATG4B_HUMAN ATG4B Cysteine protease ATG4B 3.275e-14 0.34
AOFB_MOUSE Maob Amine oxidase [flavin-containing] B 7.139e-14 0.29
DYR_HUMAN DHFR Dihydrofolate reductase 2.192e-13 0.56
PE2R1_RAT Ptger1 Prostaglandin E2 receptor EP1 subtype 2.229e-13 0.32
Q33BM1_RAT Gpr35 G protein-coupled receptor GPR35 2.329e-13 0.30
GBRA3_RAT Gabra3 Gamma-aminobutyric acid receptor subunit alpha-3 4.887e-13 0.37
PTGES_MOUSE Ptges Prostaglandin E synthase 5.476e-13 0.28
STK39_RAT Stk39 STE20/SPS1-related proline-alanine-rich protein kinase 5.514e-13 0.35
ACES_MOUSE Ache Acetylcholinesterase 7.09e-13 0.35
EST1_RABIT Liver carboxylesterase 1 1.024e-12 0.31
LIPP_PIG PNLIP Pancreatic triacylglycerol lipase 1.469e-12 0.37
OPRM_MACMU OPRM1 Mu-type opioid receptor 1.512e-12 0.31
CTDS1_HUMAN CTDSP1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 2.319e-12 0.44
ADA17_PIG ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 2.965e-12 0.32
TYTR_LEIDO TPR Trypanothione reductase 3.325e-12 0.30
HAOX1_MOUSE Hao1 Hydroxyacid oxidase 1 4.33e-12 0.29
SENP1_HUMAN SENP1 Sentrin-specific protease 1 5.412e-12 0.30
DCTP1_HUMAN DCTPP1 dCTP pyrophosphatase 1 9.273e-12 0.35
SMS1_HUMAN SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1.304e-11 0.28
NMDZ1_RAT Grin1 Glutamate receptor ionotropic, NMDA 1 1.309e-11 0.40
INHA_MYCTU inhA Enoyl-[acyl-carrier-protein] reductase [NADH] 1.791e-11 0.38
GBRA2_RAT Gabra2 Gamma-aminobutyric acid receptor subunit alpha-2 1.904e-11 0.37
I23O2_HUMAN IDO2 Indoleamine 2,3-dioxygenase 2 1.92e-11 0.31
GPR35_MOUSE Gpr35 G-protein coupled receptor 35 2.402e-11 0.30
CDK5_HUMAN CDK5 Cyclin-dependent-like kinase 5 2.441e-11 0.35
AGTR1_HUMAN AGTR1 Type-1 angiotensin II receptor 2.486e-11 0.31
CP1A2_HUMAN CYP1A2 Cytochrome P450 1A2 2.635e-11 0.39
SAE2_HUMAN UBA2 SUMO-activating enzyme subunit 2 3.108e-11 0.34
TSHR_HUMAN TSHR Thyrotropin receptor 3.495e-11 0.35
SAE1_HUMAN SAE1 SUMO-activating enzyme subunit 1 4.171e-11 0.34
PA21B_HUMAN PLA2G1B Phospholipase A2 6.319e-11 0.34
PPARG_HUMAN PPARG Peroxisome proliferator-activated receptor gamma 7.717e-11 0.35
RGS4_HUMAN RGS4 Regulator of G-protein signaling 4 7.828e-11 0.33
Q8IL11_PLAF7 M17 leucyl aminopeptidase 9.565e-11 0.33
AGTR1_BOVIN AGTR1 Type-1 angiotensin II receptor 9.845e-11 0.34
PYGL_HUMAN PYGL Glycogen phosphorylase, liver form 9.981e-11 0.33
PGH2_SHEEP PTGS2 Prostaglandin G/H synthase 2 1.233e-10 0.42
SUV91_HUMAN SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1.245e-10 0.28
PYGL_MOUSE Pygl Glycogen phosphorylase, liver form 1.257e-10 0.28
TNR6_RAT Fas Tumor necrosis factor receptor superfamily member 6 1.659e-10 0.34
GBRA5_RAT Gabra5 Gamma-aminobutyric acid receptor subunit alpha-5 1.911e-10 0.37
GRIA1_RAT Gria1 Glutamate receptor 1 2.043e-10 0.32
MMP13_HUMAN MMP13 Collagenase 3 2.293e-10 0.39
T2R14_HUMAN TAS2R14 Taste receptor type 2 member 14 2.327e-10 0.29
GBRB3_RAT Gabrb3 Gamma-aminobutyric acid receptor subunit beta-3 2.672e-10 0.37
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 2.809e-10 0.37
GBRA1_RAT Gabra1 Gamma-aminobutyric acid receptor subunit alpha-1 2.961e-10 0.37
STRP_STRP1 ska Streptokinase A 3.575e-10 0.37
MGLL_HUMAN MGLL Monoglyceride lipase 4.494e-10 0.35
GBRB2_RAT Gabrb2 Gamma-aminobutyric acid receptor subunit beta-2 4.536e-10 0.37
KAT2A_HUMAN KAT2A Histone acetyltransferase KAT2A 4.99e-10 0.34
PYGM_HUMAN PYGM Glycogen phosphorylase, muscle form 5.026e-10 0.33
NOD2_HUMAN NOD2 Nucleotide-binding oligomerization domain-containing protein 2 5.517e-10 0.43
KC1D_RAT Csnk1d Casein kinase I isoform delta 7.158e-10 0.37
Q8I2J3_PLAF7 M18 aspartyl aminopeptidase 7.326e-10 0.31
PYGL_RAT Pygl Glycogen phosphorylase, liver form 8.49e-10 0.28
IRAK4_HUMAN IRAK4 Interleukin-1 receptor-associated kinase 4 8.907e-10 0.42
DYR_STAAW folA Dihydrofolate reductase 1.045e-09 0.28
AK1C2_HUMAN AKR1C2 Aldo-keto reductase family 1 member C2 1.654e-09 0.32
GRK6_HUMAN GRK6 G protein-coupled receptor kinase 6 1.671e-09 0.30
P2RX4_HUMAN P2RX4 P2X purinoceptor 4 2.325e-09 0.34
GBRG2_RAT Gabrg2 Gamma-aminobutyric acid receptor subunit gamma-2 2.477e-09 0.37
IRAK1_HUMAN IRAK1 Interleukin-1 receptor-associated kinase 1 2.541e-09 0.36
SMCA2_HUMAN SMARCA2 Probable global transcription activator SNF2L2 2.944e-09 0.31
CH10_HUMAN HSPE1 10 kDa heat shock protein, mitochondrial 3.525e-09 0.31
CH60_HUMAN HSPD1 60 kDa heat shock protein, mitochondrial 3.525e-09 0.31
V1BR_RAT Avpr1b Vasopressin V1b receptor 3.688e-09 0.32
ACOD_HUMAN SCD Acyl-CoA desaturase 4.514e-09 0.32
TGM2_HUMAN TGM2 Protein-glutamine gamma-glutamyltransferase 2 5.745e-09 0.37
NORA_STAAU norA Quinolone resistance protein NorA 5.907e-09 0.29
ACRO_PIG ACR Acrosin 6.196e-09 0.30
MK08_HUMAN MAPK8 Mitogen-activated protein kinase 8 1.138e-08 0.38
MEP50_HUMAN WDR77 Methylosome protein 50 1.26e-08 0.39
ACES_HUMAN ACHE Acetylcholinesterase 1.269e-08 0.38
CSN5_HUMAN COPS5 COP9 signalosome complex subunit 5 1.322e-08 0.29
MK08_RAT Mapk8 Mitogen-activated protein kinase 8 1.399e-08 0.30
ANM5_HUMAN PRMT5 Protein arginine N-methyltransferase 5 1.545e-08 0.39
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 1.664e-08 0.37
PTR1_LEIMA PTR1 Pteridine reductase 1 1.97e-08 0.30
AOFA_BOVIN MAOA Amine oxidase [flavin-containing] A 2.372e-08 0.43
COLA_CLOPE colA Collagenase ColA 3.184e-08 0.32
GSK3B_MOUSE Gsk3b Glycogen synthase kinase-3 beta 3.526e-08 0.30
Q7ZJM1_9HIV1 pol Integrase 3.639e-08 0.42
MAZF_ECOLI mazF Endoribonuclease toxin MazF 4.535e-08 0.31
GSHR_HUMAN GSR Glutathione reductase, mitochondrial 4.633e-08 0.34
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 4.637e-08 0.38
ABC3A_HUMAN APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A 6.41e-08 0.36
TA2R_HUMAN TBXA2R Thromboxane A2 receptor 6.451e-08 0.38
CSK22_HUMAN CSNK2A2 Casein kinase II subunit alpha' 7.117e-08 0.31
UBP47_HUMAN USP47 Ubiquitin carboxyl-terminal hydrolase 47 7.196e-08 0.29
POLG_WNV Genome polyprotein 7.385e-08 0.35
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 8.17e-08 0.35
S22A6_RAT Slc22a6 Solute carrier family 22 member 6 9.328e-08 0.29
MMP13_RAT Mmp13 Collagenase 3 9.771e-08 0.30
S27A1_HUMAN SLC27A1 Long-chain fatty acid transport protein 1 9.919e-08 0.33
Q76353_9HIV1 Integrase 9.989e-08 0.36
KAT2B_HUMAN KAT2B Histone acetyltransferase KAT2B 1.016e-07 0.37
GPR35_HUMAN GPR35 G-protein coupled receptor 35 1.058e-07 0.38
PTGES_HUMAN PTGES Prostaglandin E synthase 1.069e-07 0.41
MITF_HUMAN MITF Microphthalmia-associated transcription factor 1.157e-07 0.34
ACES_ELEEL ache Acetylcholinesterase 1.161e-07 0.34
HSF1_MOUSE Hsf1 Heat shock factor protein 1 1.267e-07 0.41
FABI_BACSU fabI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI 1.47e-07 0.31
STE24_YEAST STE24 CAAX prenyl protease 1 1.599e-07 0.33
GSTM2_HUMAN GSTM2 Glutathione S-transferase Mu 2 1.641e-07 0.30
PGH2_RAT Ptgs2 Prostaglandin G/H synthase 2 1.812e-07 0.29
5HT3A_CAVPO HTR3A 5-hydroxytryptamine receptor 3A 1.858e-07 0.31
KCNK9_HUMAN KCNK9 Potassium channel subfamily K member 9 2.2e-07 0.32
MMP8_HUMAN MMP8 Neutrophil collagenase 2.211e-07 0.35
Q38C41_TRYB2 Phosphotransferase 2.287e-07 0.32
MRP1_HUMAN ABCC1 Multidrug resistance-associated protein 1 2.518e-07 0.36
XCT_HUMAN SLC7A11 Cystine/glutamate transporter 2.532e-07 0.28
NLRP3_HUMAN NLRP3 NACHT, LRR and PYD domains-containing protein 3 2.657e-07 0.32
HDA11_HUMAN HDAC11 Histone deacetylase 11 3.052e-07 0.35
ALDR_HUMAN AKR1B1 Aldo-keto reductase family 1 member B1 3.205e-07 0.36
MCL1_HUMAN MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 3.312e-07 0.44
CATL2_HUMAN CTSV Cathepsin L2 3.381e-07 0.33
MMP1_HUMAN MMP1 Interstitial collagenase 3.602e-07 0.35
KCMA1_HUMAN KCNMA1 Calcium-activated potassium channel subunit alpha-1 3.805e-07 0.31
UBE2N_HUMAN UBE2N Ubiquitin-conjugating enzyme E2 N 4.214e-07 0.37
RCE1_YEAST RCE1 CAAX prenyl protease 2 4.58e-07 0.34
DYR1A_RAT Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4.993e-07 0.41
EGLN1_HUMAN EGLN1 Egl nine homolog 1 5.406e-07 0.37
RFA1_HUMAN RPA1 Replication protein A 70 kDa DNA-binding subunit 5.53e-07 0.30
SYUA_HUMAN SNCA Alpha-synuclein 6.55e-07 0.34
AA1R_BOVIN ADORA1 Adenosine receptor A1 6.71e-07 0.35
CHLE_HUMAN BCHE Cholinesterase 7.157e-07 0.32
EDNRA_RAT Ednra Endothelin-1 receptor 7.337e-07 0.37
S12A2_HUMAN SLC12A2 Solute carrier family 12 member 2 7.383e-07 0.29
TMIG3_HUMAN TMIGD3 Transmembrane domain-containing protein TMIGD3 7.643e-07 0.35
SGMR2_HUMAN TMEM97 Sigma intracellular receptor 2 8.83e-07 0.31
NOX4_HUMAN NOX4 NADPH oxidase 4 9.003e-07 0.39
CP2D6_HUMAN CYP2D6 Cytochrome P450 2D6 9.519e-07 0.39
HDAC1_HUMAN HDAC1 Histone deacetylase 1 1.12e-06 0.40
PRIO_SHEEP PRNP Major prion protein 1.159e-06 0.31
TAU_HUMAN MAPT Microtubule-associated protein tau 1.267e-06 0.34
ERCC5_HUMAN ERCC5 DNA repair protein complementing XP-G cells 1.41e-06 0.31
MDR1B_MOUSE Abcb1b ATP-dependent translocase ABCB1 1.654e-06 0.35
CBPB1_HUMAN CPB1 Carboxypeptidase B 1.759e-06 0.31
EST2_HUMAN CES2 Cocaine esterase 1.814e-06 0.31
GALR3_HUMAN GALR3 Galanin receptor type 3 1.84e-06 0.31
EBNA1_EBVB9 EBNA1 Epstein-Barr nuclear antigen 1 1.868e-06 0.33
PD2R2_HUMAN PTGDR2 Prostaglandin D2 receptor 2 1.988e-06 0.38
MCHR1_HUMAN MCHR1 Melanin-concentrating hormone receptor 1 2.066e-06 0.34
NOD1_HUMAN NOD1 Nucleotide-binding oligomerization domain-containing protein 1 2.53e-06 0.43
AK1C1_HUMAN AKR1C1 Aldo-keto reductase family 1 member C1 2.712e-06 0.31
CAC1C_RABIT CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C 3.225e-06 0.34
PGH2_HUMAN PTGS2 Prostaglandin G/H synthase 2 3.409e-06 0.36
LUCI_AQULA Luciferin 4-monooxygenase 3.527e-06 0.30
PA2GX_HUMAN PLA2G10 Group 10 secretory phospholipase A2 3.96e-06 0.29
KLK7_HUMAN KLK7 Kallikrein-7 4.419e-06 0.34
FACE2_HUMAN RCE1 CAAX prenyl protease 2 4.488e-06 0.33
ATS5_HUMAN ADAMTS5 A disintegrin and metalloproteinase with thrombospondin motifs 5 4.727e-06 0.33
DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase 4.957e-06 0.28
PGH1_SHEEP PTGS1 Prostaglandin G/H synthase 1 5.112e-06 0.36
CP27B_MOUSE Cyp27b1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 5.652e-06 0.28
Q8IEK1_PLAF7 M1-family alanyl aminopeptidase 6.254e-06 0.29
RPA1_HUMAN POLR1A DNA-directed RNA polymerase I subunit RPA1 6.644e-06 0.29
PORCN_HUMAN PORCN Protein-serine O-palmitoleoyltransferase porcupine 6.738e-06 0.30
CAC1G_HUMAN CACNA1G Voltage-dependent T-type calcium channel subunit alpha-1G 7.079e-06 0.36
XDH_RAT Xdh Xanthine dehydrogenase/oxidase 7.299e-06 0.30
PTGDS_MOUSE Ptgds Prostaglandin-H2 D-isomerase 7.355e-06 0.29
AGP1_YEAST AGP1 General amino acid permease AGP1 7.705e-06 0.28
MEX5_CAEEL mex-5 Zinc finger protein mex-5 8.677e-06 0.32
GPR55_HUMAN GPR55 G-protein coupled receptor 55 9.618e-06 0.33
FEN1_HUMAN FEN1 Flap endonuclease 1 9.936e-06 0.31